BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0175.p (434 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA1433 [L] COG2256 ATPase related to the helicase subunit of th... 612 e-175 NMB1258 [L] COG2256 ATPase related to the helicase subunit of th... 610 e-174 RSc2338 [L] COG2256 ATPase related to the helicase subunit of th... 605 e-173 PA2613 [L] COG2256 ATPase related to the helicase subunit of the... 522 e-148 PM0257 [L] COG2256 ATPase related to the helicase subunit of the... 476 e-134 >NMA1433 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase NmA Neisseria meningitidis Z2491 Length = 436 Score = 612 bits (1579), Expect = e-175, Method: Compositional matrix adjust. Identities = 308/438 (70%), Positives = 360/438 (82%), Gaps = 9/438 (2%) Query: 1 MADLFAQEPAAPLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGK 60 M DLFA+EP APLAE LRP TLD+V+GQ HL+GEGKPLR+A + GKPHSM+ WGPPGVGK Sbjct: 1 MTDLFAREPYAPLAERLRPHTLDDVVGQEHLIGEGKPLRVAVEGGKPHSMLLWGPPGVGK 60 Query: 61 TTLARLTATAFECEFIALSAVFSGVKDIRAAMEQAEQNLAMGKHTILFVDEIHRFNKSQQ 120 TTLAR+ A +F +F+ +SAVFSGVKDIR A+++AE L G+ TILFVDE+HRFNK+QQ Sbjct: 61 TTLARILAQSFNAQFLPVSAVFSGVKDIREAIDKAEIALQQGRATILFVDEVHRFNKAQQ 120 Query: 121 DALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDEELKQLLKRAQDKALG 180 DA LP+ ESGL+TFIGATTENPSFEVN ALLSRAQVYVL+ L+ ++LK+L+ K L Sbjct: 121 DAFLPHVESGLLTFIGATTENPSFEVNPALLSRAQVYVLQPLSSDDLKKLIA----KVLA 176 Query: 181 DLEFDQQATDT-----IIGYADGDARRFLNLLEQTDTAARTTGTRLVTAEFLQNALTLNS 235 E+ + +T ++ DGDARR LNLLEQ AA T + +TAEFL ++L Sbjct: 177 LPEYQEFTIETDAQKLLVNTVDGDARRLLNLLEQLLRAADTRRLKNLTAEFLADSLGAQI 236 Query: 236 RRFDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGL 295 RRFDKGG++FY+QISALHKSVRGSHP+AALYW RMLDGG DPRYL+RRIVR+AWEDIGL Sbjct: 237 RRFDKGGESFYNQISALHKSVRGSHPNAALYWFCRMLDGGTDPRYLARRIVRIAWEDIGL 296 Query: 296 ADPRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKS 355 ADPRA+QIANDAA T+ERLGSPEGELAL QAV+YLA AAKSNAGY AYN R FVK++ S Sbjct: 297 ADPRALQIANDAAATFERLGSPEGELALAQAVLYLAAAAKSNAGYKAYNQMRHFVKENAS 356 Query: 356 REVPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPDGIEEPGWYQPVPRGLEI 415 EVPVHLRNAPTKLMKELGYG EYRYAHDEPNAYAAGE+Y+PDG++EP +YQPVPRGLEI Sbjct: 357 DEVPVHLRNAPTKLMKELGYGREYRYAHDEPNAYAAGESYMPDGLDEPDFYQPVPRGLEI 416 Query: 416 KIGEKLATLRQWDEEARK 433 KIGEKLA L+ DEE K Sbjct: 417 KIGEKLAWLKSLDEEVLK 434 >NMB1258 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Nme Neisseria meningitidis MC58 Length = 436 Score = 610 bits (1572), Expect = e-174, Method: Compositional matrix adjust. Identities = 307/438 (70%), Positives = 359/438 (81%), Gaps = 9/438 (2%) Query: 1 MADLFAQEPAAPLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGK 60 M DLFA+EP APLAE LRP TLD+V+GQ HL+GEGKPLR+A + GKPHSM+ WGPPGVGK Sbjct: 1 MTDLFAREPDAPLAERLRPHTLDDVVGQEHLIGEGKPLRVAVEGGKPHSMLLWGPPGVGK 60 Query: 61 TTLARLTATAFECEFIALSAVFSGVKDIRAAMEQAEQNLAMGKHTILFVDEIHRFNKSQQ 120 TTLAR+ A +F +F+ +SAVFSGVKDIR A+++AE L G+ TILFVDE+HRFNK+QQ Sbjct: 61 TTLARILAQSFNAQFLPVSAVFSGVKDIREAIDKAEIALQQGRATILFVDEVHRFNKAQQ 120 Query: 121 DALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDEELKQLLKRAQDKALG 180 DA LP+ ESGL+TFIGATTENPSFEVN ALLSRAQVYVL+ L+ ++LK+L+ K L Sbjct: 121 DAFLPHVESGLLTFIGATTENPSFEVNPALLSRAQVYVLQPLSSDDLKKLIA----KVLA 176 Query: 181 DLEFDQQATDT-----IIGYADGDARRFLNLLEQTDTAARTTGTRLVTAEFLQNALTLNS 235 E+ + +T ++ ADGDARR LNLLEQ AA T + +TAEFL ++L Sbjct: 177 LPEYQEFTIETDAQKLLVNTADGDARRLLNLLEQLLRAADTRRLKNLTAEFLADSLGAQI 236 Query: 236 RRFDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGL 295 RRFDKGG++FY+QISALHKSVRGSHP+AALYW RMLDGG DPRYL+RRIVR+AWEDIGL Sbjct: 237 RRFDKGGESFYNQISALHKSVRGSHPNAALYWFCRMLDGGTDPRYLARRIVRIAWEDIGL 296 Query: 296 ADPRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKS 355 ADPRA QIANDAA T+ERLGSPEGELAL QAV+YLA AAKSNAGY AYN R FVK++ S Sbjct: 297 ADPRAFQIANDAAATFERLGSPEGELALAQAVLYLAAAAKSNAGYKAYNQMRHFVKENAS 356 Query: 356 REVPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPDGIEEPGWYQPVPRGLEI 415 EVPVHLRNAPTKLMKELGYG EYRYAHDEPNAY+AGE+Y+PDG++EP +YQPVPRGLEI Sbjct: 357 DEVPVHLRNAPTKLMKELGYGREYRYAHDEPNAYSAGESYMPDGLDEPDFYQPVPRGLEI 416 Query: 416 KIGEKLATLRQWDEEARK 433 KIGEKL L+ DEE K Sbjct: 417 KIGEKLEWLKSLDEEVLK 434 >RSc2338 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Rso Ralstonia solanacearum Length = 449 Score = 605 bits (1560), Expect = e-173, Method: Compositional matrix adjust. Identities = 314/435 (72%), Positives = 348/435 (80%), Gaps = 7/435 (1%) Query: 2 ADLFAQEPAA--PLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVG 59 A LF P A PLAE LRP ++DEVIGQ HLLG KPLR+AF SG+PHSMI WGPPGVG Sbjct: 3 ASLFPDAPPAHMPLAERLRPHSVDEVIGQQHLLGPSKPLRVAFASGEPHSMILWGPPGVG 62 Query: 60 KTTLARLTATAFECEFIALSAVFSGVKDIRAAMEQAEQNLAMGKHTILFVDEIHRFNKSQ 119 KTTLARL A AF+ EFIALSAV SGVKDIR A+E+AEQ A G+ T++FVDE+HRFNKSQ Sbjct: 63 KTTLARLMADAFDAEFIALSAVLSGVKDIRDAVERAEQFRAHGRRTLVFVDEVHRFNKSQ 122 Query: 120 QDALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDEELKQLLKRAQDKAL 179 QDA LP+ ESGL TFIGATTENPSFEVN ALLSRA VYVLKSL+D+ELKQL +RA+ + L Sbjct: 123 QDAFLPHVESGLFTFIGATTENPSFEVNGALLSRAAVYVLKSLSDDELKQLAERARQE-L 181 Query: 180 GDLEFDQQATDTIIGYADGDARRFLNLLEQTDTAART-TGTRLVTA---EFLQNALTLNS 235 G LE+ A D ++ ADGD R+ LN +E AAR G+ V A L +AL+ N Sbjct: 182 GGLEWAPAAVDAVVASADGDGRKLLNNIEIVTRAARAQAGSETVPAIDEALLASALSENL 241 Query: 236 RRFDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGL 295 RRFDKGGD FYDQISALHKSVRGS PDAALYW RMLDGGADPRYL+RRIVRMAWEDIGL Sbjct: 242 RRFDKGGDAFYDQISALHKSVRGSDPDAALYWFCRMLDGGADPRYLARRIVRMAWEDIGL 301 Query: 296 ADPRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKS 355 ADPRA +I DAA TYERLGSPEGELAL QA+IYLA+A KSNAGYNAYNAARAFV DKS Sbjct: 302 ADPRAARITLDAAETYERLGSPEGELALAQALIYLAIAPKSNAGYNAYNAARAFVGHDKS 361 Query: 356 REVPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPDGIEEPGWYQPVPRGLEI 415 R VPVHLRNAPT+LMKELGYGH YRYAHDEP AYAAGETY PD + GWY P PRGLE Sbjct: 362 RAVPVHLRNAPTRLMKELGYGHAYRYAHDEPEAYAAGETYFPDDLSPQGWYVPTPRGLEG 421 Query: 416 KIGEKLATLRQWDEE 430 KIG+KL LR+ D + Sbjct: 422 KIGDKLRHLRELDAQ 436 >PA2613 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Pae Pseudomonas aeruginosa Length = 441 Score = 522 bits (1345), Expect = e-148, Method: Compositional matrix adjust. Identities = 269/432 (62%), Positives = 318/432 (73%), Gaps = 8/432 (1%) Query: 3 DLFAQEPAA-PLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGKT 61 DLF EP A PLA LRP LDE +GQ HLL GKPLR A + G HSMIFWGPPGVGKT Sbjct: 2 DLFRSEPVAQPLAARLRPANLDEYVGQEHLLARGKPLREALEQGALHSMIFWGPPGVGKT 61 Query: 62 TLARLTATAFECEFIALSAVFSGVKDIRAAMEQAEQNLAM-GKHTILFVDEIHRFNKSQQ 120 TLARL A + F +SAV SGVK+IR A+E A+Q+ A G+ TILFVDE+HRFNKSQQ Sbjct: 62 TLARLLAQVSDAHFETISAVLSGVKEIRQAVEVAKQHAAQYGRRTILFVDEVHRFNKSQQ 121 Query: 121 DALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDEELKQLLKRA--QDKA 178 DA LPY E G + FIGATTENPSFE+N+ALLSRA+VYVLKSL + L++L+ RA +DK Sbjct: 122 DAFLPYVEDGTLIFIGATTENPSFELNNALLSRARVYVLKSLDEAALRKLVGRALNEDKG 181 Query: 179 LGD--LEFDQQATDTIIGYADGDARRFLNLLEQTDTAARTTGTRLVTAEFLQNALTLNSR 236 LG L +++ ++ ADGD RR LNLLE A ++ E LQN L R Sbjct: 182 LGKRKLRLPEESFQVLLAAADGDGRRLLNLLENAADLAEDGSE--ISPELLQNLLGDTRR 239 Query: 237 RFDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGLA 296 RFDKGG+ FYDQISALHKSVRGS+PDAALYW RMLDGG DP Y++RR+VRMA E++G A Sbjct: 240 RFDKGGEAFYDQISALHKSVRGSNPDAALYWFARMLDGGCDPLYIARRVVRMASEEVGNA 299 Query: 297 DPRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKSR 356 DPRA+ + A ERLGSPEGELA+ QA++YLA A KSNA Y+A+NAA V + SR Sbjct: 300 DPRALGLCLSAWDVQERLGSPEGELAVAQAIVYLACAPKSNAVYSAFNAAMRDVAESGSR 359 Query: 357 EVPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPDGIEEPGWYQPVPRGLEIK 416 EVP+HLRNAPTKLMK LGYG EYRYAHDEP+AYAAGE Y P+ +E +YQPVPRGLE+K Sbjct: 360 EVPLHLRNAPTKLMKSLGYGEEYRYAHDEPDAYAAGEDYFPEDLEPRRYYQPVPRGLELK 419 Query: 417 IGEKLATLRQWD 428 I +KL L + D Sbjct: 420 IRDKLEHLAELD 431 >PM0257 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Pmu Pasteurella multocida Length = 445 Score = 476 bits (1226), Expect = e-134, Method: Compositional matrix adjust. Identities = 239/435 (54%), Positives = 307/435 (70%), Gaps = 6/435 (1%) Query: 5 FAQEPAAPLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGKTTLA 64 FAQ+ PLA +RP T + GQSHL+GEGKPLR A +G HSMI WGPPG GKTTLA Sbjct: 8 FAQQAFQPLAARMRPTTFAQYCGQSHLIGEGKPLRKALDAGHVHSMILWGPPGTGKTTLA 67 Query: 65 RLTATAFECEFIALSAVFSGVKDIRAAMEQAEQNLAMGKHTILFVDEIHRFNKSQQDALL 124 + A + +SAV SG+K+IR A+E+A++N + TILFVDE+HRFNKSQQDA L Sbjct: 68 EIIAHQIHADVERISAVTSGIKEIREAIERAKENRLAERRTILFVDEVHRFNKSQQDAFL 127 Query: 125 PYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDEELKQLLKRA---QDKALGD 181 P+ E G + FIGATTENPSFE+N+ALLSRA+VY+LKSL+ +E+ ++LK+A +++ LG Sbjct: 128 PHIEDGTIIFIGATTENPSFELNNALLSRAKVYILKSLSTQEITEVLKQALLDEERGLGK 187 Query: 182 LEF--DQQATDTIIGYADGDARRFLNLLE-QTDTAARTTGTRLVTAEFLQNALTLNSRRF 238 + F ++ + + Y +GDAR LN LE D A T + +T L+N L RF Sbjct: 188 VRFVLEENVLECLAEYVNGDARLALNSLELMADMAEETEAGKALTLSLLKNVLGERQARF 247 Query: 239 DKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGLADP 298 DK GD FYD ISALHKSVRGS PDAALYW R+L G DP Y++RR++ +A ED+G ADP Sbjct: 248 DKQGDRFYDAISALHKSVRGSAPDAALYWYARILAAGGDPLYVARRLLAIASEDVGNADP 307 Query: 299 RAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKSREV 358 RAMQ+A A + R+G+ EGE A+ QA++YLAVA KSNA Y A+N A+ VK+ EV Sbjct: 308 RAMQVALAAWDCFTRVGAAEGERAIAQAIVYLAVAPKSNAVYRAFNQAKQHVKETPDYEV 367 Query: 359 PVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPDGIEEPGWYQPVPRGLEIKIG 418 P HLRNAPT LMK LGYG YRYAHDE +AYAAGE Y P+ +++ +Y P RG+EIKI Sbjct: 368 PAHLRNAPTHLMKTLGYGEAYRYAHDEEHAYAAGENYFPEALKDTQYYFPTHRGMEIKIK 427 Query: 419 EKLATLRQWDEEARK 433 EKL LRQ D++++K Sbjct: 428 EKLDWLRQQDQQSKK 442