BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0171.p (318 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2342 [O] COG0492 Thioredoxin reductase Rso Ralstonia solanace... 498 e-141 VC1182 [O] COG0492 Thioredoxin reductase Vch Vibrio cholerae 480 e-135 YPO1374 [O] COG0492 Thioredoxin reductase Ype Yersinia pestis 477 e-134 trxB [O] COG0492 Thioredoxin reductase Eco Escherichia coli K12 471 e-133 ZtrxB [O] COG0492 Thioredoxin reductase EcZ Escherichia coli O15... 471 e-133 >RSc2342 [O] COG0492 Thioredoxin reductase Rso Ralstonia solanacearum Length = 318 Score = 498 bits (1282), Expect = e-141, Method: Compositional matrix adjust. Identities = 236/316 (74%), Positives = 278/316 (87%), Gaps = 3/316 (0%) Query: 6 KHAKVLILGSGPAGYSAAVYAARANLNPVLITGVEQGGQLMTTTDVENWPGDPLGVQGPE 65 KHAKVLILGSGPAGY+AA+YAARANLNP+LITG+ QGGQLMTTT+VENWP D G+QGPE Sbjct: 3 KHAKVLILGSGPAGYTAAIYAARANLNPMLITGLAQGGQLMTTTEVENWPADREGLQGPE 62 Query: 66 LMQRLLQHAERFKTEIIFDHIHTTKLSERPFRLIGDSGEYTADALIIATGASAQYLGLPS 125 LMQR L+HAERF T+++FDHIHT L+E+P RL+GDSGEYT DALII+TGASAQYLGLPS Sbjct: 63 LMQRFLEHAERFSTDVVFDHIHTAHLTEKPIRLVGDSGEYTCDALIISTGASAQYLGLPS 122 Query: 126 EQAFMGRGVSACATCDGFFYRGKEVAVVGGGNTAVEEALYLSNIASKVTIIHRRDKFRAE 185 E+ F GRGVSACATCDGFFY+G+EVAVVGGGNTAVEEALYL+NIASKVT+IHRRDKFRAE Sbjct: 123 EETFSGRGVSACATCDGFFYKGQEVAVVGGGNTAVEEALYLANIASKVTLIHRRDKFRAE 182 Query: 186 PILIDRLLHKVSEGKIAIQWHHTLDEVVGDDSGVTGIKIKSTQDDAI--TEIPVHGLFIA 243 PIL+DRLL + +GKI I+++ LDEV+GDDSGVTG++++ +A E+ + G+FIA Sbjct: 183 PILVDRLLEQQKKGKIEIKYNTVLDEVLGDDSGVTGVRLRGVNGNATGAEEVRLAGVFIA 242 Query: 244 IGHKPNTSIFEGQLAM-QNGYLKTRTGTEGFATATSIDGVFAAGDVQDHVYRQAITSAGT 302 IGHKPNT +F+GQL M + GYL+T++G G ATAT+I GVFAAGDVQDH+YRQAITSAGT Sbjct: 243 IGHKPNTDLFKGQLDMNETGYLRTQSGLVGNATATNIPGVFAAGDVQDHIYRQAITSAGT 302 Query: 303 GCMAALDAQRYLEGLE 318 GCMAALDAQRYLE E Sbjct: 303 GCMAALDAQRYLENQE 318 >VC1182 [O] COG0492 Thioredoxin reductase Vch Vibrio cholerae Length = 318 Score = 480 bits (1235), Expect = e-135, Method: Compositional matrix adjust. Identities = 223/310 (71%), Positives = 265/310 (85%) Query: 6 KHAKVLILGSGPAGYSAAVYAARANLNPVLITGVEQGGQLMTTTDVENWPGDPLGVQGPE 65 KH+K+LILGSGPAGY+AAVYAARANL PVL+TG++QGGQL TTT+VENWPGD G+ GP Sbjct: 5 KHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPA 64 Query: 66 LMQRLLQHAERFKTEIIFDHIHTTKLSERPFRLIGDSGEYTADALIIATGASAQYLGLPS 125 LM+R+ +HAERF TEI+FDHI++ LS RPFRL GDS EYT DALII+TGASA+YLGL S Sbjct: 65 LMERMKEHAERFDTEIVFDHINSVDLSSRPFRLTGDSQEYTCDALIISTGASAKYLGLES 124 Query: 126 EQAFMGRGVSACATCDGFFYRGKEVAVVGGGNTAVEEALYLSNIASKVTIIHRRDKFRAE 185 E+AF GRGVSACATCDGFFYR ++VAVVGGGNTAVEEALYLSNIAS+V ++HRRD FR+E Sbjct: 125 EEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLVHRRDSFRSE 184 Query: 186 PILIDRLLHKVSEGKIAIQWHHTLDEVVGDDSGVTGIKIKSTQDDAITEIPVHGLFIAIG 245 ILIDRL+ KV+ G I + H TLDEV+GD+ GVTG+++K TQ D + V G+FIAIG Sbjct: 185 KILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVFIAIG 244 Query: 246 HKPNTSIFEGQLAMQNGYLKTRTGTEGFATATSIDGVFAAGDVQDHVYRQAITSAGTGCM 305 H+PN+ IFEGQL M+NGY+ ++G EG AT TSI+GVFAAGDV DH YRQAITSAGTGCM Sbjct: 245 HQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCM 304 Query: 306 AALDAQRYLE 315 AALDA+RYL+ Sbjct: 305 AALDAERYLD 314 >YPO1374 [O] COG0492 Thioredoxin reductase Ype Yersinia pestis Length = 320 Score = 477 bits (1227), Expect = e-134, Method: Compositional matrix adjust. Identities = 223/315 (70%), Positives = 266/315 (84%) Query: 3 TTPKHAKVLILGSGPAGYSAAVYAARANLNPVLITGVEQGGQLMTTTDVENWPGDPLGVQ 62 +T KH+K++ILGSGPAGY+AAVYAARANL PVLITG+E+GGQL TTT+VENWPGDP G+ Sbjct: 2 STAKHSKLIILGSGPAGYTAAVYAARANLKPVLITGMEKGGQLTTTTEVENWPGDPEGLT 61 Query: 63 GPELMQRLLQHAERFKTEIIFDHIHTTKLSERPFRLIGDSGEYTADALIIATGASAQYLG 122 GP LM+R+ +HAE+F+TEIIFDHI + L RPFRL GD EYT DALIIATGASA+YLG Sbjct: 62 GPALMERMHEHAEKFQTEIIFDHISSVDLQNRPFRLFGDGAEYTCDALIIATGASARYLG 121 Query: 123 LPSEQAFMGRGVSACATCDGFFYRGKEVAVVGGGNTAVEEALYLSNIASKVTIIHRRDKF 182 + SE+AF G+GVSACATCDGFFYR ++VAVVGGGNTAVEEALYL+NIA++V +IHRRD F Sbjct: 122 MASEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLANIAAEVHLIHRRDTF 181 Query: 183 RAEPILIDRLLHKVSEGKIAIQWHHTLDEVVGDDSGVTGIKIKSTQDDAITEIPVHGLFI 242 R+E ILIDRL+ KV G I + TLDEV+GDD GVTG+++KST D E+ V G+FI Sbjct: 182 RSEKILIDRLMEKVKNGNIVLHTDRTLDEVLGDDMGVTGVRLKSTHSDETEELAVAGVFI 241 Query: 243 AIGHKPNTSIFEGQLAMQNGYLKTRTGTEGFATATSIDGVFAAGDVQDHVYRQAITSAGT 302 AIGH PNT IF QLA++NGY+K ++G +G AT TSI GVFAAGDV DH+YRQAITSAGT Sbjct: 242 AIGHSPNTGIFSDQLALENGYIKVQSGLQGNATQTSIPGVFAAGDVMDHIYRQAITSAGT 301 Query: 303 GCMAALDAQRYLEGL 317 GCMAALDA+RYL+GL Sbjct: 302 GCMAALDAERYLDGL 316 >trxB [O] COG0492 Thioredoxin reductase Eco Escherichia coli K12 Length = 321 Score = 471 bits (1212), Expect = e-133, Method: Compositional matrix adjust. Identities = 225/315 (71%), Positives = 266/315 (84%), Gaps = 1/315 (0%) Query: 4 TPKHAKVLILGSGPAGYSAAVYAARANLNPVLITGVEQGGQLMTTTDVENWPGDPLGVQG 63 T KH+K+LILGSGPAGY+AAVYAARANL PVLITG+E+GGQL TTT+VENWPGDP + G Sbjct: 3 TTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTG 62 Query: 64 PELMQRLLQHAERFKTEIIFDHIHTTKLSERPFRLIGDSGEYTADALIIATGASAQYLGL 123 P LM+R+ +HA +F+TEIIFDHI+ L RPFRL GD+GEYT DALIIATGASA+YLGL Sbjct: 63 PLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGL 122 Query: 124 PSEQAFMGRGVSACATCDGFFYRGKEVAVVGGGNTAVEEALYLSNIASKVTIIHRRDKFR 183 PSE+AF GRGVSACATCDGFFYR ++VAV+GGGNTAVEEALYLSNIAS+V +IHRRD FR Sbjct: 123 PSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFR 182 Query: 184 AEPILIDRLLHKVSEGKIAIQWHHTLDEVVGDDSGVTGIKIKSTQD-DAITEIPVHGLFI 242 AE ILI RL+ KV G I + + TL+EV GD GVTG++++ TQ+ D I + V GLF+ Sbjct: 183 AEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFV 242 Query: 243 AIGHKPNTSIFEGQLAMQNGYLKTRTGTEGFATATSIDGVFAAGDVQDHVYRQAITSAGT 302 AIGH PNT+IFEGQL ++NGY+K ++G G AT TSI GVFAAGDV DH+YRQAITSAGT Sbjct: 243 AIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGT 302 Query: 303 GCMAALDAQRYLEGL 317 GCMAALDA+RYL+GL Sbjct: 303 GCMAALDAERYLDGL 317 >ZtrxB [O] COG0492 Thioredoxin reductase EcZ Escherichia coli O157:H7 EDL933 Length = 321 Score = 471 bits (1212), Expect = e-133, Method: Compositional matrix adjust. Identities = 225/315 (71%), Positives = 266/315 (84%), Gaps = 1/315 (0%) Query: 4 TPKHAKVLILGSGPAGYSAAVYAARANLNPVLITGVEQGGQLMTTTDVENWPGDPLGVQG 63 T KH+K+LILGSGPAGY+AAVYAARANL PVLITG+E+GGQL TTT+VENWPGDP + G Sbjct: 3 TTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTG 62 Query: 64 PELMQRLLQHAERFKTEIIFDHIHTTKLSERPFRLIGDSGEYTADALIIATGASAQYLGL 123 P LM+R+ +HA +F+TEIIFDHI+ L RPFRL GD+GEYT DALIIATGASA+YLGL Sbjct: 63 PLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGL 122 Query: 124 PSEQAFMGRGVSACATCDGFFYRGKEVAVVGGGNTAVEEALYLSNIASKVTIIHRRDKFR 183 PSE+AF GRGVSACATCDGFFYR ++VAV+GGGNTAVEEALYLSNIAS+V +IHRRD FR Sbjct: 123 PSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFR 182 Query: 184 AEPILIDRLLHKVSEGKIAIQWHHTLDEVVGDDSGVTGIKIKSTQD-DAITEIPVHGLFI 242 AE ILI RL+ KV G I + + TL+EV GD GVTG++++ TQ+ D I + V GLF+ Sbjct: 183 AEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFV 242 Query: 243 AIGHKPNTSIFEGQLAMQNGYLKTRTGTEGFATATSIDGVFAAGDVQDHVYRQAITSAGT 302 AIGH PNT+IFEGQL ++NGY+K ++G G AT TSI GVFAAGDV DH+YRQAITSAGT Sbjct: 243 AIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGT 302 Query: 303 GCMAALDAQRYLEGL 317 GCMAALDA+RYL+GL Sbjct: 303 GCMAALDAERYLDGL 317