BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0124.p (548 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0663 [GEPR] COG0477 Permeases of the major facilitator superf... 669 0.0 BS_yusP [GEPR] COG0477 Permeases of the major facilitator superf... 229 1e-59 DR0258 [GEPR] COG0477 Permeases of the major facilitator superfa... 226 8e-59 DRA0061 [GEPR] COG0477 Permeases of the major facilitator superf... 213 9e-55 DR1327 [GEPR] COG0477 Permeases of the major facilitator superfa... 211 4e-54 >RSp0663 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 537 Score = 669 bits (1727), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/531 (65%), Positives = 428/531 (80%), Gaps = 3/531 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MALHT HS QVLPF+ES LA LGICFV++LVALDQT+VGTALPT+VAELKGF+LYAW Sbjct: 8 MALHTALPHSHTQVLPFKESLLAMLGICFVVVLVALDQTVVGTALPTVVAELKGFDLYAW 67 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSV+TVP+FGRLGD++GRKPFV+ASI+VF AS +CGMA SM FLV AR LQG Sbjct: 68 VATSYLLTSVVTVPVFGRLGDFYGRKPFVVASIVVFTLASVMCGMAGSMAFLVWARALQG 127 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT +A +ADLFPD RVRLRWQ++LS SFGIA A+GP+LGG++TQ LGWR VFY Sbjct: 128 IGGGMLVGTAYACIADLFPDARVRLRWQVLLSASFGIANAIGPTLGGWMTQALGWRSVFY 187 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 N+P GV+ L+F WRF+PH+R HAG++R DW GALLI+ +LG+LQL VE LP+ G++ Sbjct: 188 VNVPFGVLGLWFAWRFLPHLRQSLHAGRIRPDWQGALLITAALGALQLSVEWLPRHGLSL 247 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 +L L +S AAF LW WEQRA QP+LPFEM+RD ALA+LF+L+ L+GF+MF++L YAP Sbjct: 248 PVLGWLVLSAAAFAGLWWWEQRAEQPLLPFEMVRDPALATLFVLAALSGFSMFALLFYAP 307 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP++AGL+ITPLV CIT+ SI+NGR++TRIP P +M+ GFAL+A + G+ Sbjct: 308 LLFQGGFGMSPQQAGLVITPLVVCITLGSIINGRLVTRIPRPTVMLYAGFALLALALAGM 367 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 R T + L +ML G GLG VLPNLTVFAQQ+A R HLGIATALLQSLRM+GGM+ Sbjct: 368 AASSRATPQLALTLLMLLAGLGLGFVLPNLTVFAQQSAGRAHLGIATALLQSLRMVGGMI 427 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+ GTLVS+ Y AGV AL D A QWL+ +DPE+L++H+ Q+ LLAQ+ AGHDG+ Sbjct: 428 GTALVGTLVSERYAAGVGDALRADGATQWLRRLADPEILIDHEAQTALLAQMQSAGHDGA 487 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVMS 547 ALL AAR LV AIH+G+ +A V A+VGLW VRRVPP+ VEPV + Sbjct: 488 ALLGAARHVLVSAIHLGLIVAAVVAVVGLWRVRRVPPVAL---YHVEPVQT 535 >BS_yusP [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 541 Score = 229 bits (585), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 147/434 (33%), Positives = 238/434 (54%), Gaps = 38/434 (8%) Query: 34 RESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVATAYLLTSVITVPIFG 93 + + L T G+ + ALD TIVGTA+P IV +L G + W+ TAYLLTS VPI G Sbjct: 11 KRTLLIT-GLIIAMFFSALDGTIVGTAMPKIVGDLGGLSMMTWLTTAYLLTSTTIVPIAG 69 Query: 94 RLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFASVADL 153 +L D GR+ ++ +I+F+ ASALCGMAN+M L++ RGLQGIGGG+++ + DL Sbjct: 70 KLADLLGRRIVYVSGLIIFMAASALCGMANNMTELIIFRGLQGIGGGIMMPMAMIVIGDL 129 Query: 154 FPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFYCNLPIGVISLFFVWRFV 213 F + R ++Q + +G+A+ +GP +GG++ L W+WVFY NLP+G+I++ F+ R Sbjct: 130 FTGKQ-RAKFQGVFGAIYGLASVIGPQIGGWIVDSLNWKWVFYINLPVGIIAVIFIAR-- 186 Query: 214 PHIRHMQHAGKMRLDWPG---------ALLISLSLG-------SLQLLVELLPKRGVTSG 257 ++ Q G + D G +LL++LS G S Q+L G Sbjct: 187 -GLQGRQQTGPINFDIAGIFTMIVGVVSLLLALSFGGKDYAWDSWQIL-----------G 234 Query: 258 MLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAPL 317 + L + + +F + E +A +PILP + ++R L L+ MF + + P Sbjct: 235 LFALALIGIVSFIIV---ESKAKEPILPMYLFKNRTFTFLNLIGFFMSIGMFGAITFVPF 291 Query: 318 LFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIP-NPNLMMNLGFALIAASCLGI 376 QG G+S E+G ++TP++ + + SI+ G+++ +I P ++ G ++A L + Sbjct: 292 FMQGIVGVSASESGTIMTPMMISMIITSIIGGQLVYKIGIKPQIIT--GMLVMAGGFLLL 349 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 D T K + M G G+GLV+P LT+ Q++ ++E LG+ T+ Q R IGG Sbjct: 350 TTLDLDTSKLVATSFMAIIGLGMGLVMPILTLALQESFSKEELGVVTSSSQFFRSIGGTF 409 Query: 437 GTAITGTLVSQMYG 450 G + G +++ G Sbjct: 410 GITMLGAVMNARSG 423 >DR0258 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 544 Score = 226 bits (577), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 175/512 (34%), Positives = 264/512 (51%), Gaps = 20/512 (3%) Query: 29 QVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVATAYLLTSVIT 88 L RE LA GI V+ L +L+ T+VG+A+P ++++L GF LYAW TAY LT+ +T Sbjct: 13 NTLSEREKLLAFAGILTVLFLSSLNMTVVGSAMPRVISDLGGFHLYAWAFTAYSLTTTVT 72 Query: 89 VPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFA 148 +PI G L D +GR+P ++ I+VF S G SM L+ R +QGIGGG L+ F Sbjct: 73 IPIVGTLSDRYGRRPLILLGIVVFALGSMGLGFVQSMEQLIALRAIQGIGGGTLMAMSFT 132 Query: 149 SVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFYCNLPIGVISLFF 208 ++ADLF P R R+Q +GI++ VGP +GGFLT GWR VF+ NLP +++LFF Sbjct: 133 AIADLF-TPIERGRYQGYTGAVWGISSVVGPLVGGFLTDHFGWRSVFFLNLPFALLALFF 191 Query: 209 VWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTSGMLVLLAVSVAA 268 +WRF + K D GA L++ ++ +L L V +L + Sbjct: 192 IWRFFRLPAPTPGSVKGGFDALGATLLAGAVTTLTLAVSWGGGTYAWDSPRILGLLGATL 251 Query: 269 FYALWKWEQRAAQP--ILPFEMLRDRALASLFLLSVLAGF----AMFSMLMYAPLLFQGG 322 W A Q IL +LRDR + LL+ LAGF M++ ++Y PL QG Sbjct: 252 ALGAWYAAHSARQERAILDLGLLRDRGI----LLASLAGFLVSAGMYAAILYLPLYMQGV 307 Query: 323 FGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGIVLCDRV 382 G S +GL + PL+ + + S ++G++++R ++ +G AL+A+ L + + Sbjct: 308 RGSSASGSGLALAPLMGGMILTSTLSGQLVSRTGRYKRLI-VGGALVASLALVLSSTLSL 366 Query: 383 TGKGFL-LAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGMLGTAIT 441 + +L + +M+ G GLG V LT+ Q AA R+ LG AT Q R IGG L ++ Sbjct: 367 STPLWLAVTMMILLGLGLGPVNSQLTLAVQNAAPRQKLGSATGGNQFFRQIGGTLAVSLF 426 Query: 442 GTLVSQMYGAGVEKALEG---DHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDG--S 496 G LV+ + L A ++P +L + +L L + GH + Sbjct: 427 GALVNAHLSHDLSAKLPAAVRRLPAPMQDAIANPNLLTSERATHLLGWALKKMGHHEMLA 486 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMV 528 +++A R +VGAI + A LVGL V Sbjct: 487 PIMQALRGVMVGAIDQ--VFLVSAGLVGLAFV 516 >DRA0061 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 643 Score = 213 bits (542), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 161/444 (36%), Positives = 234/444 (52%), Gaps = 31/444 (6%) Query: 22 DSAH--SSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVAT 79 D AH + ++L R G+ + L ALDQTIV ALP IV+EL G LY+WV T Sbjct: 12 DPAHYINYAELLDLRTKKFIVFGVLLALFLSALDQTIVSAALPRIVSELNGLNLYSWVTT 71 Query: 80 AYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMA----------NSMLFLV 129 AYLL+S VPI+G+L D +GRKP ++ I+VF+ SALCG++ + M+ LV Sbjct: 72 AYLLSSAALVPIYGKLSDLYGRKPVLVFGIVVFLIGSALCGLSGEPFLGNLFGSPMMQLV 131 Query: 130 LARGLQGIGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGL 189 + RGLQGIG L FA VADLF +PR R ++Q + FG+++ VGP LGGFLT L Sbjct: 132 VFRGLQGIGAAALATVAFAIVADLF-EPRERAKYQGLFGAVFGLSSVVGPLLGGFLTDQL 190 Query: 190 GWRWVFYCNLPIGVISLFFVWRFVPHIRHMQHAGKMR--LDWPGALLISLSLGSLQLLVE 247 WRWVFY N+PIG+++L ++ +P + A +R +D+ GA+LI + ++ LL+ Sbjct: 191 SWRWVFYVNVPIGLVALAVIFARMPRL-----ASGLRGSVDYLGAVLIVIF--TVPLLLA 243 Query: 248 LLPKRGVTSG-----MLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSV 302 L T+G ML L S+AA A WE+R PI+P + D +A Sbjct: 244 LTWGADGTAGWTDAKMLGLFGTSLAALLAFIFWERRHESPIVPLTLFADPTIAWTMTSRF 303 Query: 303 LAGFAMFSMLMYAPLLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMM 362 L G +++ L G S AGL PL + + +G + R + ++ Sbjct: 304 LLGAGFLGAVLFLTLYLVNVAGFSATGAGLATLPLTLGFVIGAQGSGLLAARSGHYKSLL 363 Query: 363 NLGF--ALIAASCLGIVLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLG 420 + A++A L V D T G L A M G GLG + T+ AQ A A +G Sbjct: 364 VGAYVVAVLAFWWLSTVQVD--TPYGLLAARMFLVGLGLGPSVSLFTLAAQNAVAPYQIG 421 Query: 421 IATALLQSLRMIGGMLGTAITGTL 444 + T++ + +GG +G A+ G + Sbjct: 422 VVTSVGTFFQQLGGTIGIALFGAI 445 >DR1327 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 477 Score = 211 bits (536), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 158/438 (36%), Positives = 230/438 (52%), Gaps = 23/438 (5%) Query: 34 RESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVATAYLLTSVITVPIFG 93 R LAT+G+ + L AL+ ++V TA+P+++ +L G LYA YLLTS + P++G Sbjct: 14 RARLLATVGLIVGVFLNALESSVVATAMPSVINDLHGQSLYALPFAMYLLTSTVGSPLWG 73 Query: 94 RLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFASVADL 153 R D GRK + ++F+ SALCG A SM +L+ AR LQG+G G L+ V +L Sbjct: 74 RASDLVGRKRLYLVGAVLFLVGSALCGAAQSMGWLIGARALQGLGAGALLTLSMTIVGEL 133 Query: 154 FPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFYCNLPIGVISLFFVWRFV 213 + + R R Q +S +GI+ GP LGG+LT+ L WRW FY +LP G+++LF V RF+ Sbjct: 134 Y-SLQERSRVQAFISAVWGISGLAGPLLGGWLTETLSWRWTFYVSLPFGLLALFMVSRFL 192 Query: 214 PHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTSGMLVLLAVSVAAFYALW 273 + A +LDW GA L +L G L G+ + L+ + VA Sbjct: 193 HETGERRAA---QLDWAGAALFTLGSG--------LTIWGLEMKLWSLVGLGVATLVGAV 241 Query: 274 KWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAPLLFQGGFGLSPREAGLL 333 E R P+LP LR+R A F + L G A F ++ Y PL QG G AG + Sbjct: 242 LLELRHPAPLLPMRALRERTPAVAFAGNFLGGAAYFGVIAYLPLYAQGVSGKGATAAGAI 301 Query: 334 ITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGIVLCDR----VTGKGFLL 389 +TP++ T+ SI++ ++I IP L +GFAL+ L + VT Sbjct: 302 LTPMLVGWTLTSILSAQLIRFIPLARL-SQIGFALLTLMFLALTFTVHSPLWVTS----- 355 Query: 390 AVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGMLGTAITGTLV-SQM 448 A+ A G G+G + +L + AQQAA+R LG T+ + R +GG LGTA+ L+ S Sbjct: 356 ALGFAVGMGMGFSMLSLLLAAQQAASRGELGAVTSGVMFARQMGGALGTALMALLIGSHA 415 Query: 449 YGAGVEKALEGDHAAQWL 466 G G + EG A +L Sbjct: 416 IGVGGIELAEGLRRAYFL 433