BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0100.p (229 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1662 [U] COG2095 Multiple antibiotic transporter Ccr Caulobact... 109 5e-24 STM1521 [U] COG2095 Multiple antibiotic transporter Sty Salmonel... 100 3e-21 marC [U] COG2095 Multiple antibiotic transporter Eco Escherichia... 97 4e-20 ECs2136 [U] COG2095 Multiple antibiotic transporter Ecs Escheric... 96 6e-20 ZydeB [U] COG2095 Multiple antibiotic transporter EcZ Escherichi... 95 1e-19 >CC1662 [U] COG2095 Multiple antibiotic transporter Ccr Caulobacter vibrioides Length = 228 Score = 109 bits (272), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 74/206 (35%), Positives = 122/206 (59%), Gaps = 6/206 (2%) Query: 16 LLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSHVLTFFGISLP 75 L I+NP+G A +F +G SR ++AR + + +L+ ++ +G ++L FFG+S+ Sbjct: 22 LFSIVNPVGAALIFDQAMGGRSRPERLKLARAIGFYAFLVLLGSLLLGGYILNFFGVSIG 81 Query: 76 IVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFYPMSFPLTVGP 135 +RV GGL+VA+ W LL D Q+ +V +T D +F+P++ P T GP Sbjct: 82 ALRVAGGLVVAIRAWGLLMDPEQNED--RKVNQTESAQSHHDV----AFFPLTMPFTTGP 135 Query: 136 GTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYAHKLVHLMGRLGTMVV 195 G+I+ +I L + PT A+L AAL A++++LCY+ + +++ L+G G V+ Sbjct: 136 GSISVAIALSSQRPTEGDAVAPFFIGASLAAALVAVLVWLCYSASGQVMRLLGPSGARVL 195 Query: 196 LRLSAFILLCIGIQIFWSGMSALLAE 221 RL AF+LLCIG+QI SG+ L+A+ Sbjct: 196 SRLVAFLLLCIGVQIIASGVENLVAK 221 >STM1521 [U] COG2095 Multiple antibiotic transporter Sty Salmonella typhimurium LT2 Length = 221 Score = 100 bits (249), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 68/215 (31%), Positives = 117/215 (54%), Gaps = 13/215 (6%) Query: 6 LKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSH 65 KA+ L V LLP+ NPL +F L GN++ + R + ++ + +++ A + G Sbjct: 5 FKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYYAGQL 64 Query: 66 VLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFY 125 V+ FGIS+P +R+ GGL+VA G+++L + P AK+ E+L D+ +F Sbjct: 65 VMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESPE--AKSKSEELADEPTANIAFV 122 Query: 126 PMSFPLTVGPGTI------AASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNY 179 P++ P T GPGTI A+++ G P DWVI V + A+ A++++ C Sbjct: 123 PLAMPSTAGPGTIAMIISSASTVRHGGEFP----DWVIMVAPPIIFLAV-AVILWGCLRS 177 Query: 180 AHKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSG 214 + ++ L+G+ G + RL F+L+C+G+Q +G Sbjct: 178 SGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIING 212 >marC [U] COG2095 Multiple antibiotic transporter Eco Escherichia coli K12 Length = 221 Score = 96.7 bits (239), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 67/212 (31%), Positives = 118/212 (55%), Gaps = 5/212 (2%) Query: 6 LKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSH 65 KA+ L V LLP+ NPL +F L GN++ + R + ++ + +++ A + G Sbjct: 5 FKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQL 64 Query: 66 VLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFY 125 V+ FGIS+P +R+ GGL+VA G+++L Q +I + AK+ E+L D+ +F Sbjct: 65 VMDTFGISIPGLRIAGGLIVAFIGFRMLFP--QQKAIDSPEAKSKSEELEDEPSANIAFV 122 Query: 126 PMSFPLTVGPGTIAASITLGA--NTPTRLLDWVISVGSAALGAALTALVIFLCYNYAHKL 183 P++ P T GPGTIA I+ + + DWV+ V + L L A++++ + + Sbjct: 123 PLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMV-APPLIFFLVAVILWGSLRSSGAI 181 Query: 184 VHLMGRLGTMVVLRLSAFILLCIGIQIFWSGM 215 + L+G+ G + RL F+L+C+G+Q +G+ Sbjct: 182 MRLVGKGGIEAISRLMGFLLVCMGVQFIINGI 213 >ECs2136 [U] COG2095 Multiple antibiotic transporter Ecs Escherichia coli O157:H7 Length = 221 Score = 95.9 bits (237), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 67/212 (31%), Positives = 118/212 (55%), Gaps = 5/212 (2%) Query: 6 LKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSH 65 KA+ L V LLP+ NPL +F L GN++ + R + ++ + +++ A + G Sbjct: 5 FKAIGLGLVVLLPLANPLTTVALFLGLAGNMNGAERNRQSLMASVYVFAIMMVAYYAGQL 64 Query: 66 VLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFY 125 V+ FGIS+P +R+ GGL+VA G+++L Q +I + AK+ E+L D+ +F Sbjct: 65 VMDTFGISIPGLRIAGGLIVAFIGFRML--FPQQKAIDSPEAKSKSEELEDEPSANIAFV 122 Query: 126 PMSFPLTVGPGTIAASITLGA--NTPTRLLDWVISVGSAALGAALTALVIFLCYNYAHKL 183 P++ P T GPGTIA I+ + + DWV+ V + L L A++++ + + Sbjct: 123 PLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMV-APPLIFFLVAVILWGSLRSSGAI 181 Query: 184 VHLMGRLGTMVVLRLSAFILLCIGIQIFWSGM 215 + L+G+ G + RL F+L+C+G+Q +G+ Sbjct: 182 MRLVGKGGIEAISRLMGFLLVCMGVQFIINGI 213 >ZydeB [U] COG2095 Multiple antibiotic transporter EcZ Escherichia coli O157:H7 EDL933 Length = 221 Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 67/212 (31%), Positives = 118/212 (55%), Gaps = 5/212 (2%) Query: 6 LKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSH 65 KA+ L V LLP+ NPL +F L GN++ + R + ++ + +++ A + G Sbjct: 5 FKAIGLGLVVLLPLANPLTTVALFLGLAGNMNGAERNRQSLMASVYVFAIMMVAYYAGQL 64 Query: 66 VLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFY 125 V+ FGIS+P +R+ GGL+VA G+++L Q +I + AK+ E+L D+ +F Sbjct: 65 VMDTFGISIPGLRIAGGLIVAFIGFRML--FPQXKAIDSPEAKSKSEELEDEPSANIAFV 122 Query: 126 PMSFPLTVGPGTIAASITLGA--NTPTRLLDWVISVGSAALGAALTALVIFLCYNYAHKL 183 P++ P T GPGTIA I+ + + DWV+ V + L L A++++ + + Sbjct: 123 PLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMV-APPLIFFLVAVILWGSLRSSGAI 181 Query: 184 VHLMGRLGTMVVLRLSAFILLCIGIQIFWSGM 215 + L+G+ G + RL F+L+C+G+Q +G+ Sbjct: 182 MRLVGKGGIEAISRLMGFLLVCMGVQFIINGI 213