BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0065.p (404 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2949 [GEPR] COG0477 Permeases of the major facilitator superf... 194 3e-49 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 159 1e-38 yhaU [GEPR] COG0477 Permeases of the major facilitator superfami... 148 2e-35 ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfam... 148 2e-35 ECs4005 [GEPR] COG0477 Permeases of the major facilitator superf... 148 2e-35 >lin2949 [GEPR] COG0477 Permeases of the major facilitator superfamily Lin Listeria innocua Length = 401 Score = 194 bits (493), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 123/399 (30%), Positives = 214/399 (53%), Gaps = 4/399 (1%) Query: 5 VRKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 V+ K+ +VL++L++G+ Y+D+ I + ++ + PS G++LS+FFLGY+L Sbjct: 4 VKGEKHSLMVLLVLFIGYTSVYVDKYTIGISLVTVSQDLGFDPSQKGLILSAFFLGYTLF 63 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGV-GEGAFPAASV 123 Q+P G+L +R G+RPV+ ISI++ LF + G +S+ LV+IRF+ G G +P + Sbjct: 64 QIPMGYLNNRIGARPVLAISIIIVGLFLIIFGFGYSLLFLVVIRFLSGAFGHAGYPPSVS 123 Query: 124 KGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALV 183 ++ + ++R S +++S+ + + PLLIA L+L GWR +++IGI V+F + Sbjct: 124 NYISLHIPLNKRGFAQSAMLASSGFAAFIGPLLIAQLLLSVGWRNTYYWIGIV-VIFIGL 182 Query: 184 YWFCVRPVRPGVGGAGAINKQA--FMALMKMPLMWQIVAVWFGLSIINKGLDTWMPTYLM 241 V P P + + K F L+K +W ++ ++ N GL +W+ +YL Sbjct: 183 LILLVVPKAPKIDKSTQKEKIKVPFSELLKDKQLWILLLSALFINAANYGLTSWLASYLN 242 Query: 242 TVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFFDGREKLLLIGSSLLTAVFVYCMYS 301 RG+++ V + L + ++ IGG+ + RFF G+E +++ S+L A VY +Y Sbjct: 243 EARGISISEVSYISSLAGLCILIAGVIGGYFISRFFKGKEPIVIFTFSVLGAFTVYGVYL 302 Query: 302 AASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLVGSGVGMVNLGGQLAGFISPLVI 361 + I CL F T + LP K+ + + + +N GG L GF +P++I Sbjct: 303 FDQLMLSIICLCLCNIFLIMAFTTLMGLPHKLFKQSHIATKYAAINSGGVLGGFFAPMII 362 Query: 362 GFLVSAFANYDYAFSFLIGAAFFSVLVSLFIRTHKSDSQ 400 G LV+A +Y AF FL S ++ L I+ S+ Sbjct: 363 GDLVNATNSYQSAFLFLALTFLVSGIIVLAIKKRSVISE 401 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 159 bits (401), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 126/411 (30%), Positives = 201/411 (48%), Gaps = 32/411 (7%) Query: 6 RKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLLQ 65 ++ K ++LV L++ ++YIDR ++ AA I EFHL ++G+++S+FF Y+LLQ Sbjct: 9 QRSKVRWLVAGLMWAAIAINYIDRTVLSAAAPHIQKEFHLSAVEMGVVMSAFFWSYALLQ 68 Query: 66 LPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGE-GAFPAASVK 124 LP G LADR+G + V+ ++L WSL T VTG+A SLV +R GVGE GA+P S Sbjct: 69 LPAGILADRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGEAGAYP--SNA 126 Query: 125 GVAEN-FSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALV 183 G+ F + ER ++++ S + +GS +A LIA L++ + W+ F G G+V+ +V Sbjct: 127 GITSRWFPKQERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVV 186 Query: 184 YWFCVRP---VRPGVGGAGAINKQA-----------FMALMKMPLMWQIVAVWFGLSIIN 229 + R GV A + Q M K+ + A+ G +IN Sbjct: 187 WALVFRDSPAEHEGVNAAELAHIQKGLPPARGADAPAMPWTKLLTHRNVWAMCIGFFMIN 246 Query: 230 KG---LDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFF-DGR----- 280 TW+PTYL+ RG+ L +G + LP ++ GW R + GR Sbjct: 247 YNSYFFITWLPTYLVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRVYASGRLSLTA 306 Query: 281 -EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLV 339 KL L+ ++ + ++ ++V VI C+A + + ALP + V Sbjct: 307 TRKLFLVIGLVMASSIGLAAFAQSAVVAVIL-LCIAKSGTTVAASQVWALPADVAPGNTV 365 Query: 340 GSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSF---LIGAAFFSVL 387 G+ N + G + P+V G +V A ++ A F LIG A + L Sbjct: 366 SMVAGLQNSVSNMGGVVGPIVTGAIVGATGSFIPALVFSAALIGLAILNYL 416 >yhaU [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 444 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 122/442 (27%), Positives = 207/442 (46%), Gaps = 53/442 (11%) Query: 6 RKGKY-KYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +KG + +YL+L+++++ V+Y DRA ++ A T++A E L +G + S+F Y L+ Sbjct: 10 KKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLM 69 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTG------MAWSVTSLVMIRFIFGVGEGAF 118 Q+PGGWL D++GS+ V S+ WSLFT + G +AW+ S+ +RF+ G E Sbjct: 70 QIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPS 129 Query: 119 PAASVKGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGV 178 A+ + VA F ER S++ S+ Y L L+ L +GW VF +G+ G Sbjct: 130 FPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGF 189 Query: 179 VFA-----LVYWFCVRP---------------------VRPGVGGAGAINKQAFMALMKM 212 V L++ P +PG A L+ Sbjct: 190 VLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSN 249 Query: 213 PLMWQIVAVWFGLSIINK---GLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIG 269 +M + V+FG IN TW P YL+ +G+++ VGL+ +P + G + + Sbjct: 250 RMM---LGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIP-ALCGFAGGVL 305 Query: 270 GWVMVRFFDGR-------EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFV 322 G V + R KL ++ LL + + C Y+ + V+ LA+F K F Sbjct: 306 GGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTL-VVMLMALAFFGKGF- 363 Query: 323 LATCIALP--TKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIG 380 + P + ++VG G+ N+ G +A ++PLVIG+LVS +++ A F+ Sbjct: 364 --GALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGC 421 Query: 381 AAFFSVLVSLFIRTHKSDSQMQ 402 +A +++ LF+ ++Q Sbjct: 422 SALMAMVCYLFVVGDIKRMELQ 443 >ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 444 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 122/442 (27%), Positives = 207/442 (46%), Gaps = 53/442 (11%) Query: 6 RKGKY-KYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +KG + +YL+L+++++ V+Y DRA ++ A T++A E L +G + S+F Y L+ Sbjct: 10 KKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLM 69 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTG------MAWSVTSLVMIRFIFGVGEGAF 118 Q+PGGWL D++GS+ V S+ WSLFT + G +AW+ S+ +RF+ G E Sbjct: 70 QIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPS 129 Query: 119 PAASVKGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGV 178 A+ + VA F ER S++ S+ Y L L+ L +GW VF +G+ G Sbjct: 130 FPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGF 189 Query: 179 VFA-----LVYWFCVRP---------------------VRPGVGGAGAINKQAFMALMKM 212 V L++ P +PG A L+ Sbjct: 190 VLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSN 249 Query: 213 PLMWQIVAVWFGLSIINK---GLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIG 269 +M + V+FG IN TW P YL+ +G+++ VGL+ +P + G + + Sbjct: 250 RMM---LGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIP-ALCGFAGGVL 305 Query: 270 GWVMVRFFDGR-------EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFV 322 G V + R KL ++ LL + + C Y+ + V+ LA+F K F Sbjct: 306 GGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTL-VVMLMALAFFGKGF- 363 Query: 323 LATCIALP--TKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIG 380 + P + ++VG G+ N+ G +A ++PLVIG+LVS +++ A F+ Sbjct: 364 --GALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGC 421 Query: 381 AAFFSVLVSLFIRTHKSDSQMQ 402 +A +++ LF+ ++Q Sbjct: 422 SALMAMVCYLFVVGDIKRMELQ 443 >ECs4005 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 444 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 122/442 (27%), Positives = 207/442 (46%), Gaps = 53/442 (11%) Query: 6 RKGKY-KYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +KG + +YL+L+++++ V+Y DRA ++ A T++A E L +G + S+F Y L+ Sbjct: 10 KKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLM 69 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTG------MAWSVTSLVMIRFIFGVGEGAF 118 Q+PGGWL D++GS+ V S+ WSLFT + G +AW+ S+ +RF+ G E Sbjct: 70 QIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPS 129 Query: 119 PAASVKGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGV 178 A+ + VA F ER S++ S+ Y L L+ L +GW VF +G+ G Sbjct: 130 FPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGF 189 Query: 179 VFA-----LVYWFCVRP---------------------VRPGVGGAGAINKQAFMALMKM 212 V L++ P +PG A L+ Sbjct: 190 VLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSN 249 Query: 213 PLMWQIVAVWFGLSIINK---GLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIG 269 +M + V+FG IN TW P YL+ +G+++ VGL+ +P + G + + Sbjct: 250 RMM---LGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIP-ALCGFAGGVL 305 Query: 270 GWVMVRFFDGR-------EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFV 322 G V + R KL ++ LL + + C Y+ + V+ LA+F K F Sbjct: 306 GGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTL-VVMLMALAFFGKGF- 363 Query: 323 LATCIALP--TKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIG 380 + P + ++VG G+ N+ G +A ++PLVIG+LVS +++ A F+ Sbjct: 364 --GALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGC 421 Query: 381 AAFFSVLVSLFIRTHKSDSQMQ 402 +A +++ LF+ ++Q Sbjct: 422 SALMAMVCYLFVVGDIKRMELQ 443