BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0037.p (331 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI0921 [M] COG1087 UDP-glucose 4-epimerase Bme Brucella melite... 368 e-102 BS_galE [M] COG1087 UDP-glucose 4-epimerase Bsu Bacillus subtilis 328 1e-89 VCA0774 [M] COG1087 UDP-glucose 4-epimerase Vch Vibrio cholerae 314 2e-85 YPO1139 [M] COG1087 UDP-glucose 4-epimerase Ype Yersinia pestis 313 3e-85 RSp1101 [M] COG1087 UDP-glucose 4-epimerase Rso Ralstonia solana... 313 4e-85 >BMEI0921 [M] COG1087 UDP-glucose 4-epimerase Bme Brucella melitensis Length = 335 Score = 368 bits (945), Expect = e-102, Method: Compositional matrix adjust. Identities = 172/241 (71%), Positives = 204/241 (84%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIR 60 M ILVTGGAGYIGSHTCV+L++AGHEV+V DNF NS PE++ R+++ITG+ GDIR Sbjct: 1 MTILVTGGAGYIGSHTCVQLIEAGHEVVVVDNFDNSHPEALHRIEKITGRAPRREPGDIR 60 Query: 61 NREQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIV 120 +R +E +++ KC AVIHFAGLKAVGES E+PL+YYD NV+GT+RLL+AM+ATGVK +V Sbjct: 61 DRALMEQMIKRHKCTAVIHFAGLKAVGESSEKPLLYYDCNVLGTLRLLQAMEATGVKKLV 120 Query: 121 FSSSATVYGDPQYLPLDEAHPLSASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNPV 180 FSSSATVYGDP LP+ E PLSA+NPYGR+K+VIEDMLRD Y + W IA+LRYFNPV Sbjct: 121 FSSSATVYGDPDKLPITEDQPLSATNPYGRTKLVIEDMLRDLYNSDNSWAIAILRYFNPV 180 Query: 181 GAHESGLIGEDPGGIPNNLIPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLAR 240 GAHESGLIGEDP GIPNNL+P +AQVA GRRE+LNIWG DYPTPDGTGVRD+IHV DLA Sbjct: 181 GAHESGLIGEDPKGIPNNLMPIIAQVATGRREKLNIWGNDYPTPDGTGVRDYIHVNDLAA 240 Query: 241 G 241 G Sbjct: 241 G 241 >BS_galE [M] COG1087 UDP-glucose 4-epimerase Bsu Bacillus subtilis Length = 339 Score = 328 bits (841), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 154/241 (63%), Positives = 192/241 (79%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIR 60 M ILVTGGAGYIGSHTCVELL +G+E++V DN NSS E++ RV++ITGK L+ + D+ Sbjct: 1 MAILVTGGAGYIGSHTCVELLNSGYEIVVLDNLSNSSAEALNRVKEITGKDLTFYEADLL 60 Query: 61 NREQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIV 120 +RE ++SV E + EAVIHFAGLKAVGESV PL YY NN+ GT L EAM+ GVK IV Sbjct: 61 DREAVDSVFAENEIEAVIHFAGLKAVGESVAIPLKYYHNNLTGTFILCEAMEKYGVKKIV 120 Query: 121 FSSSATVYGDPQYLPLDEAHPLSASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNPV 180 FSSSATVYG P+ P+ E PL A+NPYG++K+++E +LRD + A +W +ALLRYFNP Sbjct: 121 FSSSATVYGVPETSPITEDFPLGATNPYGQTKLMLEQILRDLHTADNEWSVALLRYFNPF 180 Query: 181 GAHESGLIGEDPGGIPNNLIPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLAR 240 GAH SG IGEDP GIPNNL+P+VAQVA+G+ E+L+++G DYPT DGTGVRD+IHVVDLA Sbjct: 181 GAHPSGRIGEDPNGIPNNLMPYVAQVAVGKLEQLSVFGNDYPTKDGTGVRDYIHVVDLAE 240 Query: 241 G 241 G Sbjct: 241 G 241 >VCA0774 [M] COG1087 UDP-glucose 4-epimerase Vch Vibrio cholerae Length = 338 Score = 314 bits (804), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 141/241 (58%), Positives = 190/241 (78%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIR 60 M +LVTGG GYIGSHTC+++++AG ++ DN NS + R++++ G V+GDIR Sbjct: 1 MKVLVTGGMGYIGSHTCIQMIQAGMTPVILDNLYNSKVTVLDRIEKVIGVRPQFVQGDIR 60 Query: 61 NREQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIV 120 ++ L ++++ EAV+HFAGLKAVGESV++PL YYDNNV GT+ L+ AM+ GVK++V Sbjct: 61 DKALLVDLMQQHNIEAVVHFAGLKAVGESVQKPLEYYDNNVNGTLVLVAAMREAGVKSLV 120 Query: 121 FSSSATVYGDPQYLPLDEAHPLSASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNPV 180 FSSSATVYG+P +P+ E+ P A+NPYGRSK+++E+ L D+ +A+PDW I LLRYFNPV Sbjct: 121 FSSSATVYGEPTSVPITESFPTKAANPYGRSKLMVEECLTDFQKANPDWSITLLRYFNPV 180 Query: 181 GAHESGLIGEDPGGIPNNLIPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLAR 240 G+H SG +GEDP GIPNNL+PFV QVA+GRRE L+++G DYPT DGTGVRD+IHV+DLA Sbjct: 181 GSHPSGELGEDPQGIPNNLMPFVTQVAVGRREYLSVFGSDYPTKDGTGVRDYIHVMDLAD 240 Query: 241 G 241 G Sbjct: 241 G 241 >YPO1139 [M] COG1087 UDP-glucose 4-epimerase Ype Yersinia pestis Length = 338 Score = 313 bits (803), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 154/256 (60%), Positives = 191/256 (74%), Gaps = 2/256 (0%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIR 60 M +LVTGG+GYIGSHTCV+L++AG++ ++ DN CNS + R+ +TG T L GDIR Sbjct: 1 MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIR 60 Query: 61 NREQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIV 120 +R L+S+ AVIHFAGLKAVGESV +PL YY+NNV GT+ LLEAM+A VK ++ Sbjct: 61 DRTLLDSIFAAHPIHAVIHFAGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLI 120 Query: 121 FSSSATVYGDPQYLPLDEAHPL-SASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNP 179 FSSSATVYGD +P E+ P S S+PYGRSK+++E +L+D A P W + +LRYFNP Sbjct: 121 FSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQILQDVQLADPQWNMTILRYFNP 180 Query: 180 VGAHESGLIGEDPGGIPNNLIPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLA 239 VGAH SGL+GEDP GIPNNL+PF+AQVA+GRRE L I+G YPTPDGTGVRD+IHVVDLA Sbjct: 181 VGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNGYPTPDGTGVRDYIHVVDLA 240 Query: 240 RGXHGRARLHPRGGPG 255 G H A G PG Sbjct: 241 DG-HVAAMKTLHGKPG 255 >RSp1101 [M] COG1087 UDP-glucose 4-epimerase Rso Ralstonia solanacearum Length = 341 Score = 313 bits (801), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 148/240 (61%), Positives = 187/240 (77%) Query: 2 NILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIRN 61 IL+TG GYI SHT VELL AG++VI DN CNSS + R++QIT KT V+GD+R+ Sbjct: 4 TILLTGATGYIASHTWVELLDAGYQVIGLDNLCNSSAAVLARIEQITAKTPKFVQGDVRD 63 Query: 62 REQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIVF 121 R L+ + + AVIHFA LK+VGESV++PL YYDNN+ G V L AM V+ +VF Sbjct: 64 RRLLDDLFASTRISAVIHFAALKSVGESVQKPLAYYDNNMGGLVTLCAAMAHANVRQLVF 123 Query: 122 SSSATVYGDPQYLPLDEAHPLSASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNPVG 181 SSSATVYG+P +P+ E+ PLSA+NPYG++K++ E +LRD ++ W+IA LRYFNPVG Sbjct: 124 SSSATVYGNPHTVPITESFPLSATNPYGQTKLMGEQVLRDLEVSNGAWRIAYLRYFNPVG 183 Query: 182 AHESGLIGEDPGGIPNNLIPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLARG 241 AH SGLIGEDP GIPNNL+P+VAQVA GRRE+L+++GGD+PTPDGTGVRD+IHVVDLARG Sbjct: 184 AHHSGLIGEDPRGIPNNLMPYVAQVAAGRREQLSVFGGDWPTPDGTGVRDYIHVVDLARG 243