BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0015.p (1110 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB0626 [J] COG4108 Peptide chain release factor RF-3 Nme Neisse... 878 0.0 NMA0836 [J] COG4108 Peptide chain release factor RF-3 NmA Neisse... 875 0.0 RSp1662 [J] COG4108 Peptide chain release factor RF-3 Rso Ralsto... 708 0.0 PA3903 [J] COG4108 Peptide chain release factor RF-3 Pae Pseudom... 696 0.0 HI1735 [J] COG4108 Peptide chain release factor RF-3 Hin Haemoph... 691 0.0 >NMB0626 [J] COG4108 Peptide chain release factor RF-3 Nme Neisseria meningitidis MC58 Length = 531 Score = 878 bits (2268), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/528 (78%), Positives = 470/528 (89%), Gaps = 1/528 (0%) Query: 582 IAREVKRRRTFGIISHPDAGKTTLTEKLLLFSGAIQLAGTVKARKSGRHATSDWMEIEKQ 641 I +V+RRRTF IISHPDAGKTTLTEKLLLFSGAIQ AGTVK +K+G+ ATSDWMEIEKQ Sbjct: 5 ILDQVRRRRTFAIISHPDAGKTTLTEKLLLFSGAIQSAGTVKGKKTGKFATSDWMEIEKQ 64 Query: 642 RGISVASSVMQFEYRDHVVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEEQTIK 701 RGISVASSVMQF+Y+DH VNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVE QTIK Sbjct: 65 RGISVASSVMQFDYKDHTVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEAQTIK 124 Query: 702 LLNVCRMRNTPIITFMNKLDRETRDSLELLDELESVLKIQCAPVTWPIGMGKNFRGVYHL 761 LLNVCR+R+TPI+TFMNK DRE RDSLELLDE+E++LKI+CAPVTWPIGMGKNF+GVYH+ Sbjct: 125 LLNVCRLRDTPIVTFMNKYDREVRDSLELLDEVENILKIRCAPVTWPIGMGKNFKGVYHI 184 Query: 762 LRDEIMLFKAGEERANGNVEIIKGIDNPKLAEMFPLEIEQLKMEVELVHGASHPFNLDDF 821 L DEI LF+AG ER +IIKGIDNP+L + FPLEI+QL+ E+ELV AS+ FNLD+F Sbjct: 185 LNDEIYLFEAGGERLPHEFDIIKGIDNPELEQRFPLEIQQLRDEIELVQAASNEFNLDEF 244 Query: 822 LAGVQTPVFFGSAINNFGVREILDALLDWAPGPGGRDATVREVKPTEEPFSGFVFKIQAN 881 LAG TPVFFGSAINNFG++EIL++L+DWAP P RDATVR V+P E FSGF+FKIQAN Sbjct: 245 LAGELTPVFFGSAINNFGIQEILNSLIDWAPAPKPRDATVRMVEPDEPKFSGFIFKIQAN 304 Query: 882 MDPAHRDRIAFLRVCSGRFERGMKLKHLRLNRDIKVSSVVTFMASSREQVEEAYAGDIIG 941 MDP HRDRIAFLRVCSG+FERGMK+KHLR+NR+I SSVVTFM+ RE VEEAYAGDIIG Sbjct: 305 MDPKHRDRIAFLRVCSGKFERGMKMKHLRINREIAASSVVTFMSHDRELVEEAYAGDIIG 364 Query: 942 LPNHGNMQIGDSFSEGEMLQFTGIPYFAPDFFRVARIRNPLKIKQLHKGLQQLGEEGAVQ 1001 +PNHGN+QIGDSFSEGE L FTGIP+FAP+ FR RI+NPLKIKQL KGLQQLGEEGAVQ Sbjct: 365 IPNHGNIQIGDSFSEGEQLAFTGIPFFAPELFRSVRIKNPLKIKQLQKGLQQLGEEGAVQ 424 Query: 1002 VFKPVTGSDLILGAVGVLQFEVVASRLLNEYGVDAVFEGTSISSARWISCDDKKKLADFE 1061 VFKP++G+DLILGAVGVLQFEVV SRL NEYGV+AVF+ SI SARW+SCDDKKKLA+FE Sbjct: 425 VFKPMSGADLILGAVGVLQFEVVTSRLANEYGVEAVFDSASIWSARWVSCDDKKKLAEFE 484 Query: 1062 KSSAGANLAIDAAGNMAYLASSGVNLRLTQERWPEITFHATREHAAKL 1109 K++AG NLAIDA GN+AYLA + VNL LTQERWP+I FH TREH+ KL Sbjct: 485 KANAG-NLAIDAGGNLAYLAPNRVNLGLTQERWPDIVFHETREHSVKL 531 >NMA0836 [J] COG4108 Peptide chain release factor RF-3 NmA Neisseria meningitidis Z2491 Length = 531 Score = 875 bits (2260), Expect = 0.0, Method: Compositional matrix adjust. Identities = 413/528 (78%), Positives = 470/528 (89%), Gaps = 1/528 (0%) Query: 582 IAREVKRRRTFGIISHPDAGKTTLTEKLLLFSGAIQLAGTVKARKSGRHATSDWMEIEKQ 641 I +V+RRRTF IISHPDAGKTTLTEKLLLFSGAIQ AGTVK +K+G+ ATSDWM+IEKQ Sbjct: 5 ILDQVRRRRTFAIISHPDAGKTTLTEKLLLFSGAIQSAGTVKGKKTGKFATSDWMDIEKQ 64 Query: 642 RGISVASSVMQFEYRDHVVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEEQTIK 701 RGISVASSVMQF+Y+DH VNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVE QTIK Sbjct: 65 RGISVASSVMQFDYKDHTVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEAQTIK 124 Query: 702 LLNVCRMRNTPIITFMNKLDRETRDSLELLDELESVLKIQCAPVTWPIGMGKNFRGVYHL 761 LLNVCR+RNTPI+TFMNK DRE RDSLELLDE+E++L+I+CAPVTWPIGMGKNF+GVYH+ Sbjct: 125 LLNVCRLRNTPIVTFMNKYDREVRDSLELLDEVENILQIRCAPVTWPIGMGKNFKGVYHI 184 Query: 762 LRDEIMLFKAGEERANGNVEIIKGIDNPKLAEMFPLEIEQLKMEVELVHGASHPFNLDDF 821 L DEI LF+AG ER +IIKGIDNP+L + FPLEI+QL+ E+ELV AS+ FNLD+F Sbjct: 185 LNDEIYLFEAGGERLPHEFDIIKGIDNPELEQRFPLEIQQLRDEIELVQAASNEFNLDEF 244 Query: 822 LAGVQTPVFFGSAINNFGVREILDALLDWAPGPGGRDATVREVKPTEEPFSGFVFKIQAN 881 LAG TPVFFGSAINNFG++EIL++L++WAP P RDATVR V+P E FSGF+FKIQAN Sbjct: 245 LAGELTPVFFGSAINNFGIQEILNSLIEWAPAPKPRDATVRMVEPDEPKFSGFIFKIQAN 304 Query: 882 MDPAHRDRIAFLRVCSGRFERGMKLKHLRLNRDIKVSSVVTFMASSREQVEEAYAGDIIG 941 MDP HRDRIAFLRVCSG+FERGMK+KHLR+NR+I SSVVTFM+ RE VEEAYAGDIIG Sbjct: 305 MDPKHRDRIAFLRVCSGKFERGMKMKHLRINREIAASSVVTFMSHDRELVEEAYAGDIIG 364 Query: 942 LPNHGNMQIGDSFSEGEMLQFTGIPYFAPDFFRVARIRNPLKIKQLHKGLQQLGEEGAVQ 1001 +PNHGN+QIGDSFSEGE L FTGIP+FAP+ FR RI+NPLKIKQL KGLQQLGEEGAVQ Sbjct: 365 IPNHGNIQIGDSFSEGEQLTFTGIPFFAPELFRSVRIKNPLKIKQLQKGLQQLGEEGAVQ 424 Query: 1002 VFKPVTGSDLILGAVGVLQFEVVASRLLNEYGVDAVFEGTSISSARWISCDDKKKLADFE 1061 VFKP++G+DLILGAVGVLQFEVV SRL NEYGV+AVF+ SI SARW+SCDDKKKLA+FE Sbjct: 425 VFKPMSGADLILGAVGVLQFEVVTSRLANEYGVEAVFDNASIWSARWVSCDDKKKLAEFE 484 Query: 1062 KSSAGANLAIDAAGNMAYLASSGVNLRLTQERWPEITFHATREHAAKL 1109 K++AG NLAIDA GN+AYLA + VNL LTQERWP+I FH TREH+ KL Sbjct: 485 KANAG-NLAIDAGGNLAYLAPNRVNLGLTQERWPDIVFHETREHSVKL 531 >RSp1662 [J] COG4108 Peptide chain release factor RF-3 Rso Ralstonia solanacearum Length = 533 Score = 708 bits (1827), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/535 (63%), Positives = 421/535 (78%), Gaps = 13/535 (2%) Query: 577 VSTDLIAREVKRRRTFGIISHPDAGKTTLTEKLLLFSGAIQLAGTVKARKSGRHATSDWM 636 VST + +E++RRRTF IISHPDAGKTTLTEKLL F GAIQ+AG V+ARK+ RHATSDWM Sbjct: 3 VST--LQQEIRRRRTFAIISHPDAGKTTLTEKLLWFGGAIQMAGAVRARKASRHATSDWM 60 Query: 637 EIEKQRGISVASSVMQFEYR----DHVVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAA 692 E+EKQRGISV SSVMQF YR D++VNLLDTPGH+DFSEDTYR LTAVDSA+MVID+ Sbjct: 61 ELEKQRGISVTSSVMQFPYRNDGGDYIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSV 120 Query: 693 KGVEEQTIKLLNVCRMRNTPIITFMNKLDRETRDSLELLDELESVLKIQCAPVTWPIGMG 752 GVE QTIKLLNVCR+R+TPI+TF+NKLDRE R +ELLDE+E+VL+IQCAP+TWPIGMG Sbjct: 121 NGVEAQTIKLLNVCRLRSTPILTFINKLDREGRAPIELLDEIENVLQIQCAPMTWPIGMG 180 Query: 753 KNFRGVYHLLRDEIMLFKAGEERANG-NVEIIKGIDNPKLAEMFPLEIEQLKMEVELVHG 811 K+FRGVYHL+ D + LF E G +I+G+DNP+L + + E+L++++ELV G Sbjct: 181 KSFRGVYHLVNDTVQLFDPKAETEKGATAGMIQGLDNPELDRVLGSQAEELRIDIELVRG 240 Query: 812 ASHPFNLDDFLAGVQTPVFFGSAINNFGVREILDALLDWAPGPGGRDATVREVKPTEEPF 871 ASH F+ D FLAG Q PV+FGSA+NNFGV+ +LDAL+ +P P R REV P E+ F Sbjct: 241 ASHTFDKDLFLAGKQCPVYFGSAVNNFGVQSLLDALVGLSPEPLARATQTREVAPLEDKF 300 Query: 872 SGFVFKIQANMDPAHRDRIAFLRVCSGRFERGMKLKHLRLNRDIKVSSVVTFMASSREQV 931 +GFVFKIQANMDP HRDRIAF+RVCSGRFERGMKL + + + +++ +TFMA R Sbjct: 301 TGFVFKIQANMDPKHRDRIAFVRVCSGRFERGMKLLQVSTGKTVAINNAITFMAQDRNTT 360 Query: 932 EEAYAGDIIGLPNHGNMQIGDSFSEGEMLQFTGIPYFAPDFFRVARIRNPLKIKQLHKGL 991 EEAYAGDIIG+PNHG +++GD+F+EGE L+FTGIP FAP++FR AR+ NPLK KQL KGL Sbjct: 361 EEAYAGDIIGVPNHGTIRLGDAFTEGEPLRFTGIPSFAPEYFRRARLNNPLKTKQLQKGL 420 Query: 992 QQLGEEGAVQVFKPVTGSDLILGAVGVLQFEVVASRLLNEYGVDAVFEGTSISSARWISC 1051 QQL EEGA Q+F+P+ +DL+LGAVG LQF+VVA RL EYGVDA+FE ++ARW+ Sbjct: 421 QQLAEEGATQMFRPLASNDLVLGAVGTLQFDVVAHRLEYEYGVDAIFEPHECATARWLKG 480 Query: 1052 --DDKKKLADFEKSSAGANLAIDAAGNMAYLASSGVNLRLTQERWPEITFHATRE 1104 +D KL D AG N+A+D AG+ YLA S VNLRLTQER+P+I F TRE Sbjct: 481 KPEDIDKLID----KAGHNVAVDGAGDYVYLAPSQVNLRLTQERFPDIQFMETRE 531 >PA3903 [J] COG4108 Peptide chain release factor RF-3 Pae Pseudomonas aeruginosa Length = 527 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/527 (61%), Positives = 413/527 (78%), Gaps = 9/527 (1%) Query: 583 AREVKRRRTFGIISHPDAGKTTLTEKLLLFSGAIQLAGTVKARKSGRHATSDWMEIEKQR 642 A EV +RRTF IISHPDAGKTT+TEKLLL AI +AGTVK+RKS RHATSDWME+EKQR Sbjct: 5 AAEVAKRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQR 64 Query: 643 GISVASSVMQFEYRDHVVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEEQTIKL 702 GIS+ +SVMQF YR+H++NLLDTPGH+DFSEDTYR LTAVDSALMV+D KGVE +TI L Sbjct: 65 GISITTSVMQFPYREHMINLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIAL 124 Query: 703 LNVCRMRNTPIITFMNKLDRETRDSLELLDELESVLKIQCAPVTWPIGMGKNFRGVYHLL 762 + VCR+R+TPI++F+NKLDR+ RD +ELLDE+E+VLKI+ AP+TWPIG K+F+GVYHL Sbjct: 125 MEVCRLRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYKDFKGVYHLA 184 Query: 763 RDEIMLFKAGEERANGNVEIIKGIDNPK----LAEMFPLEIEQLKMEVELVHGASHPFNL 818 D I+++ G ++I+ +D+ + L +++ +E+L ELV GA H F+ Sbjct: 185 DDRIIVYVPGHGHERIETKVIEKLDSDEARAHLGDLYDNFVEEL----ELVQGACHEFDK 240 Query: 819 DDFLAGVQTPVFFGSAINNFGVREILDALLDWAPGPGGRDATVREVKPTEEPFSGFVFKI 878 D FL G TPVFFG+A+ NFGV ++LD ++DWAP P R R V+PTEE FSGFVFKI Sbjct: 241 DAFLKGEMTPVFFGTALGNFGVDQVLDCIVDWAPQPLSRATHERSVEPTEEKFSGFVFKI 300 Query: 879 QANMDPAHRDRIAFLRVCSGRFERGMKLKHLRLNRDIKVSSVVTFMASSREQVEEAYAGD 938 QANMDP HRDRIAF+R+CSG++E+GMK++H+RL +D+K++ +TF +S REQ+EEAYAGD Sbjct: 301 QANMDPKHRDRIAFMRICSGKYEKGMKMRHVRLGKDVKIADALTFFSSEREQLEEAYAGD 360 Query: 939 IIGLPNHGNMQIGDSFSEGEMLQFTGIPYFAPDFFRVARIRNPLKIKQLHKGLQQLGEEG 998 IIGL NHG +QIGD+FSEGE FTGIP+FAP+ FR R+++PLK KQL +GLQ+L EEG Sbjct: 361 IIGLHNHGTIQIGDTFSEGENFGFTGIPHFAPELFRRVRLKDPLKSKQLRQGLQELAEEG 420 Query: 999 AVQVFKPVTGSDLILGAVGVLQFEVVASRLLNEYGVDAVFEGTSISSARWISCDDKKKLA 1058 A QVF P +D+ILGAVGVLQF+VVASRL EY V+ +E ++ SARWI CDD+KKL Sbjct: 421 ATQVFFPERNNDIILGAVGVLQFDVVASRLKEEYKVECAYEAINVWSARWIECDDEKKLK 480 Query: 1059 DFEKSSAGANLAIDAAGNMAYLASSGVNLRLTQERWPEITFHATREH 1105 +F K A NL++D G++ YLA + VNL L +ERWP+I F ATREH Sbjct: 481 EF-KDKAFENLSVDGGGHLTYLAPTRVNLSLMEERWPDIRFRATREH 526 >HI1735 [J] COG4108 Peptide chain release factor RF-3 Hin Haemophilus influenzae Length = 527 Score = 691 bits (1782), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/522 (61%), Positives = 409/522 (78%), Gaps = 2/522 (0%) Query: 585 EVKRRRTFGIISHPDAGKTTLTEKLLLFSGAIQLAGTVKARKSGRHATSDWMEIEKQRGI 644 EV +RRTF IISHPDAGKTT+TEK+LL+ AIQ AG+VK + S HA SDWME+EKQRGI Sbjct: 7 EVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQTAGSVKGKGSAAHAKSDWMEMEKQRGI 66 Query: 645 SVASSVMQFEYRDHVVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEEQTIKLLN 704 S+ +SVMQF Y D +VNLLDTPGH+DFSEDTYR LTAVDS LMVID+AKGVEE+TIKL+ Sbjct: 67 SITTSVMQFPYNDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLME 126 Query: 705 VCRMRNTPIITFMNKLDRETRDSLELLDELESVLKIQCAPVTWPIGMGKNFRGVYHLLRD 764 V R+R+TPIITFMNKLDR+ RD +ELLDE+E+VLKI+CAP+TWPIG GK F+GVYHL +D Sbjct: 127 VTRLRDTPIITFMNKLDRDIRDPIELLDEVENVLKIRCAPITWPIGCGKLFKGVYHLAKD 186 Query: 765 EIMLFKAGEERANGNVEIIKGIDNPKLAEMFPLEI-EQLKMEVELVHGASHPFNLDDFLA 823 E L+++G+ V ++KG++NP+L ++ +QL+ E+ELV GAS+ F D F+ Sbjct: 187 ETYLYQSGQGSTIQAVRVVKGLNNPELDVAVGDDLAQQLREELELVQGASNEFEQDAFIK 246 Query: 824 GVQTPVFFGSAINNFGVREILDALLDWAPGPGGRDATVREVKPTEEPFSGFVFKIQANMD 883 G TPVFFG+A+ NFGV LD L WAP P R A R V+ EE FSGFVFKIQANMD Sbjct: 247 GELTPVFFGTALGNFGVDHFLDGLTQWAPKPQSRQADTRTVESAEEKFSGFVFKIQANMD 306 Query: 884 PAHRDRIAFLRVCSGRFERGMKLKHLRLNRDIKVSSVVTFMASSREQVEEAYAGDIIGLP 943 P HRDR+AF+RV SG++E+GMKLKH+R+ +D+ +S +TFMA R EEAYAGDIIGL Sbjct: 307 PKHRDRVAFMRVVSGKYEKGMKLKHVRIGKDVVISDALTFMAGDRAHAEEAYAGDIIGLH 366 Query: 944 NHGNMQIGDSFSEGEMLQFTGIPYFAPDFFRVARIRNPLKIKQLHKGLQQLGEEGAVQVF 1003 NHG +QIGD+F++GE L+FTGIP FAP+ FR R+++PLK KQL KGL QL EEGAVQVF Sbjct: 367 NHGTIQIGDTFTQGETLKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVF 426 Query: 1004 KPVTGSDLILGAVGVLQFEVVASRLLNEYGVDAVFEGTSISSARWISCDDKKKLADFEKS 1063 +P+ +DLI+GAVGVLQF+VV SRL EY V+A++E ++++ARW+ C D+KK +F++ Sbjct: 427 RPLLNNDLIVGAVGVLQFDVVVSRLKTEYNVEAIYENVNVATARWVECADEKKFEEFKRK 486 Query: 1064 SAGANLAIDAAGNMAYLASSGVNLRLTQERWPEITFHATREH 1105 + NLA+D N+ Y+A + VNL L QER+P++ F+ TREH Sbjct: 487 NE-QNLALDGGDNLTYIAPTMVNLNLAQERYPDVVFYKTREH 527