BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0156.p (372 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1411 [GEPR] COG0477 Permeases of the major facilitator superfa... 514 e-145 RSc1852 [GEPR] COG0477 Permeases of the major facilitator superf... 489 e-138 RSc1292 [GEPR] COG0477 Permeases of the major facilitator superf... 362 e-99 YPO3268 [GEPR] COG0477 Permeases of the major facilitator superf... 359 6e-99 NMA2168 [GEPR] COG0477 Permeases of the major facilitator superf... 342 6e-94 >VC1411 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 511 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 251/371 (67%), Positives = 299/371 (80%), Gaps = 2/371 (0%) Query: 1 VLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFILSM 60 +LDTTIANVSVS IAG+LG STSQGTYVITSYAVAEAI+VPLTGWLA+RFG++RVF+ Sbjct: 32 ILDTTIANVSVSNIAGSLGTSTSQGTYVITSYAVAEAISVPLTGWLASRFGSIRVFVTCF 91 Query: 61 VMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAPAAVGLWAMT 120 ++FG+FS LCG+ANS+ L+ FRVL G GGPLMPLSQTL++RIFPK K+ AA+G+W+MT Sbjct: 92 LLFGVFSLLCGLANSMSTLVMFRVLLGFVGGPLMPLSQTLMIRIFPKNKSHAAIGIWSMT 151 Query: 121 TLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIGWRMLKRYETKMSKLPIDRVGL 180 TLVAPI GPILGGVLCDQ SWPYIF+I +P A+ + W++LK++ETK + ID+VGL Sbjct: 152 TLVAPIMGPILGGVLCDQLSWPYIFFIKMPFAIAAALLCWKLLKKFETKTTHSKIDKVGL 211 Query: 181 VLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFFIAFLIWELTERNPIVDLRVFR 240 L+VVWVAALQLMLDEGK+ DWF S+ IV LAV AV+ FIAFLIWELTERNP+VDL+VFR Sbjct: 212 ALLVVWVAALQLMLDEGKDHDWFESSRIVFLAVIAVIGFIAFLIWELTERNPVVDLKVFR 271 Query: 241 HRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATWSGCISALTGILAVMTAPMVAK 300 HRG++ S+ T+ LAFGAFF V+TPLWLQ YMGYTAT SG +A GILAV AP+VA Sbjct: 272 HRGYSISMVTLSLAFGAFFSISVVTPLWLQIYMGYTATISGHATASMGILAVFLAPIVAN 331 Query: 301 MSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGWPLFLQGIGLPLFFVPLTGLAL 360 +S+ D R V GV WLG TF+R FNT DM+F QI WPLF QGIG+PLFFVPLT +AL Sbjct: 332 LSSKFDPRPFVFAGVMWLGLWTFMRGFNTVDMTFSQISWPLFFQGIGMPLFFVPLTAIAL 391 Query: 361 SSVNEKPPRRR 371 SV KP Sbjct: 392 GSV--KPHEME 400 >RSc1852 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 512 Score = 489 bits (1258), Expect = e-138, Method: Compositional matrix adjust. Identities = 241/366 (65%), Positives = 295/366 (80%) Query: 1 VLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFILSM 60 VLD TIANVSV I+G LG STSQGT+VITSYAVAEAI VPLTGWLA+RFGTVRVF ++M Sbjct: 32 VLDMTIANVSVPNISGNLGVSTSQGTWVITSYAVAEAILVPLTGWLASRFGTVRVFAVAM 91 Query: 61 VMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAPAAVGLWAMT 120 FGLFSALCG+A SLGML+A R+ QGLAGGPLMPLSQTLLLRIFPKEKA AA+GLW+MT Sbjct: 92 GCFGLFSALCGLALSLGMLVAARICQGLAGGPLMPLSQTLLLRIFPKEKAGAAIGLWSMT 151 Query: 121 TLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIGWRMLKRYETKMSKLPIDRVGL 180 T+VAP+ GPILGG LCD+YSWP+IF+IN+P+A+ C + W+ML RYE+ +++ PID+VGL Sbjct: 152 TIVAPVLGPILGGYLCDEYSWPWIFYINLPIAVGCAWAAWKMLARYESPIARNPIDKVGL 211 Query: 181 VLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFFIAFLIWELTERNPIVDLRVFR 240 L+V+WV +LQ+MLDEGK+ DWFAS+ I LAV A + F AFLIWEL +P V+LRVFR Sbjct: 212 ALLVLWVGSLQIMLDEGKQLDWFASSTIAGLAVVAAIGFAAFLIWELHAEHPAVNLRVFR 271 Query: 241 HRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATWSGCISALTGILAVMTAPMVAK 300 HRGF+ASV TI LAFGAFFG+ VLTP WLQ +MGYTA +G +A +G A+ AP+ A Sbjct: 272 HRGFSASVLTISLAFGAFFGANVLTPQWLQSFMGYTALEAGKTTAWSGFFALFAAPIAAG 331 Query: 301 MSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGWPLFLQGIGLPLFFVPLTGLAL 360 + +DARKLV GV WLG IT R TTDM+++Q+ PL G+G+P FFVP TGLA+ Sbjct: 332 LGGKVDARKLVFGGVIWLGIITLWRTVATTDMTYWQVAVPLMAMGLGIPFFFVPTTGLAM 391 Query: 361 SSVNEK 366 +SV+E+ Sbjct: 392 ASVDEE 397 >RSc1292 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 518 Score = 362 bits (928), Expect = e-99, Method: Compositional matrix adjust. Identities = 182/369 (49%), Positives = 254/369 (68%), Gaps = 2/369 (0%) Query: 1 VLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFILSM 60 VLD++IANVS+ I+G LG + +QGT+VITS+AVA AI+VPLTGWL RFG VR+F+ S+ Sbjct: 32 VLDSSIANVSIPAISGDLGVAPNQGTWVITSFAVANAISVPLTGWLTQRFGQVRLFVTSI 91 Query: 61 VMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAPAAVGLWAMT 120 ++F L S CG+A ++G LIA R+LQG GP++PLSQ+LLL +P K+ A+ LW MT Sbjct: 92 LLFVLSSWACGLAPNMGTLIAARILQGAVAGPMIPLSQSLLLSTYPPAKSSMALALWGMT 151 Query: 121 TLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIGWRMLKRYETKMSKLPIDRVGL 180 TLVAPI GPI GG + D +WP+IF+IN+PV ++ Y W + K E+ LPIDR+GL Sbjct: 152 TLVAPIMGPIFGGWISDNMTWPWIFYINIPVGILAAYATWVIYKDRESPTRALPIDRIGL 211 Query: 181 VLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFFIAFLIWELTERNPIVDLRVFR 240 L+V+WV +LQLMLD GKE DWF S EIV L V AVV F FL+WELTE +P+VDL +F+ Sbjct: 212 ALLVIWVGSLQLMLDRGKELDWFNSAEIVTLTVVAVVGFAFFLVWELTEDHPVVDLTLFK 271 Query: 241 HRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATWSGCISALTGILAVMTAPMVAK 300 R F+A V I +A+G FFG++V+ PLWLQ +GYTAT +G + A GI A++ +P++ K Sbjct: 272 GRNFSAGVVAISVAYGLFFGNLVILPLWLQTIVGYTATDAGLVMAPVGIFAILLSPVIGK 331 Query: 301 MSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGWPLFLQGIGLPLFFVPLTGLAL 360 +DAR + + ++R+ T + + + P +QG + +FF+PLT + L Sbjct: 332 NLPKMDARWVATTAFITFALVFWMRSRFTIQVDTWTLMVPTLIQGAAMAMFFIPLTSIIL 391 Query: 361 SSVNEKPPR 369 S + +P R Sbjct: 392 SGL--RPER 398 >YPO3268 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 511 Score = 359 bits (921), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 188/371 (50%), Positives = 249/371 (67%), Gaps = 4/371 (1%) Query: 1 VLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFILSM 60 VLD+TIANV++ TIAG LG+S SQGT+VITS+ VA AI++P+TGWLA R G VR+F+ S Sbjct: 26 VLDSTIANVAIPTIAGDLGSSNSQGTWVITSFGVANAISIPVTGWLAKRVGEVRLFLWST 85 Query: 61 VMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAPAAVGLWAMT 120 +F L S LCGM+NSLGMLI FRV+QGL GPL+PLSQ+LLL +P K A+ LW+MT Sbjct: 86 GLFVLASWLCGMSNSLGMLIFFRVIQGLVAGPLIPLSQSLLLNNYPPAKRSMALALWSMT 145 Query: 121 TLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIGWRMLKRYETKMSKLPIDRVGL 180 +VAPI GPILGG + D Y W +IF+IN+P+ L+ + LK ETK PID +GL Sbjct: 146 IVVAPIFGPILGGYISDNYHWGWIFFINIPIGLVVVLLAGSTLKGRETKTEIRPIDTIGL 205 Query: 181 VLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFFIAFLIWELTERNPIVDLRVFR 240 VL+VV + ALQ+MLD+GKE DWF STEI++L V AVV ++WELT+ +P++DL +F+ Sbjct: 206 VLLVVGIGALQIMLDQGKELDWFNSTEIIVLTVVAVVAITFLIVWELTDDHPVIDLSLFK 265 Query: 241 HRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATWSGCISALTGILAVMTAPMVAK 300 R FT + LA+ +FG++VL P LQ GYTATW+G SA GIL V+ +P++ + Sbjct: 266 SRNFTIGCLCLSLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGILPVLLSPLIGR 325 Query: 301 MSTTIDARKLVCIGVTWLGFITFLRAFN-TTDMSFFQIGWPLFLQGIGLPLFFVPLTGLA 359 + ID R+LV + RA+ M F WP F QG + FF+PLT + Sbjct: 326 FAHRIDMRQLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFFQGFAIACFFMPLTTIT 385 Query: 360 LSSVNEKPPRR 370 LS + PP R Sbjct: 386 LSGL---PPER 393 >NMA2168 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 516 Score = 342 bits (878), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 178/364 (48%), Positives = 241/364 (66%) Query: 1 VLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFILSM 60 VLDTTIANV+V IAG LGA+T+QGT+VITS+AVA A++VPLTG+LA R G V++F + Sbjct: 34 VLDTTIANVAVPVIAGNLGAATTQGTWVITSFAVANAVSVPLTGFLAKRIGEVKLFTAAA 93 Query: 61 VMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAPAAVGLWAMT 120 V F + S LCG+A +L L+ FR+LQG GPL+PLSQ+LL+ +P K A+ LWAMT Sbjct: 94 VGFVITSWLCGIAPNLQSLVVFRILQGFIAGPLIPLSQSLLMASYPPAKRTLALALWAMT 153 Query: 121 TLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIGWRMLKRYETKMSKLPIDRVGL 180 +VAP+ GPILGG + + W +IF+IN+P+ +I +I W+ LK ET+ K+P D VGL Sbjct: 154 VVVAPVLGPILGGWISGNWHWGWIFFINIPIGIISAWITWKHLKCRETETVKMPTDYVGL 213 Query: 181 VLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFFIAFLIWELTERNPIVDLRVFR 240 LMVV + ALQ+MLD GKE DWFAS EI+ L V A+V F++WEL E+ PIVDL +F+ Sbjct: 214 TLMVVGIGALQMMLDRGKELDWFASGEIITLGVVALVCLSYFIVWELGEKYPIVDLSLFK 273 Query: 241 HRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATWSGCISALTGILAVMTAPMVAK 300 R FT + L F + G++ L PL LQ +GYT+TW+G +A GIL V +P++ + Sbjct: 274 DRNFTVGIIATSLGFMVYMGTLTLLPLVLQTNLGYTSTWAGLAAAPVGILPVFLSPLIGR 333 Query: 301 MSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGWPLFLQGIGLPLFFVPLTGLAL 360 ID R LV F + R DM + WP F QG+G+ +FF+PLT + L Sbjct: 334 FGNKIDMRLLVTASFLTFAFTFYWRTDFYADMDIGNVIWPQFWQGVGVAMFFLPLTTITL 393 Query: 361 SSVN 364 S + Sbjct: 394 SHMK 397