BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0151.p (376 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1148 Non COG 393 e-109 PA2630 [S] COG2850 Uncharacterized conserved protein Pae Pseudom... 259 5e-69 STM1229 [S] COG2850 Uncharacterized conserved protein Sty Salmon... 216 5e-56 ycfD [S] COG2850 Uncharacterized conserved protein Eco Escherich... 213 7e-55 ZycfD [S] COG2850 Uncharacterized conserved protein EcZ Escheric... 213 7e-55 >RSc1148 Non COG Length = 409 Score = 393 bits (1009), Expect = e-109, Method: Compositional matrix adjust. Identities = 205/389 (52%), Positives = 264/389 (67%), Gaps = 14/389 (3%) Query: 1 MAGMKKLDLLGGITPAQFLRDYWHKKPLLIRNAIP-----GFSAPLPRQELFDLARRDDV 55 +A + LLGG++P F+R +W KKPLLIR A+ PL L LARR+DV Sbjct: 17 LAAGRPAQLLGGLSPRDFMRTHWQKKPLLIRQALSPEDMRALHFPLSPDALIKLARREDV 76 Query: 56 ESRLITHREGGWDMQHGPFNK--LPPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDAR 113 ESRLI G W HGPFN+ LP K + WTLLVQGVNL PA DAL+++FRF+PDAR Sbjct: 77 ESRLIAQTRGRWTFNHGPFNERPLPSRKARNWTLLVQGVNLVEPAVDALMQRFRFIPDAR 136 Query: 114 LDDLMISYASDGGGVGPHFDSYDVFLLQAHGQRRWRISAQDDLTLEEGVPLKILSHFQAE 173 LDD+MIS+A+DGGGVGPHFDSYDVFLLQAHG+RRWRIS+Q+DLTL +PLKIL++F E Sbjct: 137 LDDVMISFATDGGGVGPHFDSYDVFLLQAHGRRRWRISSQNDLTLVPDLPLKILANFTPE 196 Query: 174 EEFVLEPGDMLYLPPHYAHDGVAVGECMTYSIGFRAPTYQELGESFLEFMMDTI----DL 229 EEF+LEPGDMLYLPPHYAHDGVA G+CMTYS+GFR+P+Y+EL FL F+ T+ D Sbjct: 197 EEFILEPGDMLYLPPHYAHDGVAEGDCMTYSVGFRSPSYRELAGHFLGFLSQTLEDNPDF 256 Query: 230 PGRYADPDLKTSARPAELQADMIARIRDELNKIRFTDDDITIFLGQHLSEPKPSVFFEAP 289 GRY DP+ K RP EL M+ + +LN +R+T + + F G +L+EPK V F Sbjct: 257 EGRYTDPEQKPVERPGELPTAMVRALAQKLNALRWTPELVGEFFGAYLTEPKDHVEFVTQ 316 Query: 290 PQELSFARFFQGTKKRGLVLHRKTRMLYRGSHVFINGESFQVSRQDKAILARLADHRMLE 349 P+ LS ARF +K G+VL +T+ LY +ING++F+ S A L+ L+D R Sbjct: 317 PR-LSLARFTARARKEGIVLDARTQALYDAQRFWINGDTFEPSDTLLAWLSALSDQRGAS 375 Query: 350 KNDFDQASE--DLLEALHQWHESGWIEFV 376 D A++ DL++ LH W+E GW++ Sbjct: 376 AEAVDAAADLPDLMDTLHAWYEEGWLQLA 404 >PA2630 [S] COG2850 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 389 Score = 259 bits (663), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 158/390 (40%), Positives = 223/390 (57%), Gaps = 17/390 (4%) Query: 1 MAGMKKLDLLGGITPAQFLRDYWHKKPLLIRNAIPGFSAPLPRQELFDLARRDDVESRLI 60 M L LLGG+T A+FLRDYW +KPLL+R AIP F +PL EL L+ + VESR++ Sbjct: 1 MNADTPLQLLGGLTAAEFLRDYWQRKPLLVRQAIPDFESPLSADELAGLSLEESVESRIV 60 Query: 61 -THREGGWDMQHGPFNK--LPPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDL 117 H + W+M+ GPF + L ++ WTLLVQ V+ P LL QFRF+P R+DD+ Sbjct: 61 LEHGKTPWEMRRGPFQEEDYQHLPEQDWTLLVQAVDQFVPEVAQLLEQFRFLPSWRIDDV 120 Query: 118 MISYASDGGGVGPHFDSYDVFLLQAHGQRRWRIS--AQDDLTLEEGVPLKILSHFQAEEE 175 MISYA+ GGGVGPHFD+YDVFLLQ HG+RRW++ D L E L+IL+ F+ +E Sbjct: 121 MISYAAPGGGVGPHFDNYDVFLLQGHGRRRWKVGQMCSSDSPLREHADLRILADFEQSDE 180 Query: 176 FVLEPGDMLYLPPHYAHDGVAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYAD 235 +VLEPGDMLYLPP AH G+A ECMTYSIGFRAP+ E+ F +F+ + RY D Sbjct: 181 WVLEPGDMLYLPPRLAHYGIAEDECMTYSIGFRAPSAAEVLTHFTDFLGQFLSDEERYTD 240 Query: 236 PDLK-TSARPAELQADMIARIRDELNKIRFTDDDITIFLGQHLSEPK--PSVFFEAPPQE 292 L+ P ++Q D + R++ + + + + + GQ ++EP+ V E P+E Sbjct: 241 AGLQPVGDDPHQIQRDALERLQGLIQEHMSDERLLLTWFGQFMTEPRYPELVAGEEIPEE 300 Query: 293 LSFARFFQGTKKRGLVLHRKTRMLYR----GSHVFINGESFQVSRQDKAILARLADHRML 348 F G LV + R+ + G +F +G+S + Q K +L + L Sbjct: 301 ELFGALEDGAL---LVRNPSARLAWSEIDIGLVLFASGQSVLLPGQLKELLKLVCSADAL 357 Query: 349 EKNDFDQ--ASEDLLEALHQWHESGWIEFV 376 + Q A +D + L + + G +EF Sbjct: 358 HLENLGQWLADDDARKLLAELVKQGSLEFA 387 >STM1229 [S] COG2850 Uncharacterized conserved protein Sty Salmonella typhimurium LT2 Length = 373 Score = 216 bits (551), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 126/347 (36%), Positives = 192/347 (55%), Gaps = 10/347 (2%) Query: 18 FLRDYWHKKPLLIRNAIPGFSAPLPRQELFDLARRDDVESRLITHREGGWDMQHGPFNKL 77 FL +W K+P++++ F PL EL LA +++SRL++H++G W + HGPF Sbjct: 12 FLERHWQKRPVVLKRGFSNFIDPLSPDELAGLAMESEIDSRLVSHQDGKWQVSHGPFESY 71 Query: 78 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYASDGGGVGPHFDSYDV 137 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 72 DHLGESNWSLLVQAVNHWHEPTAALMRPFRALPDWRIDDLMISFSVPGGGVGPHLDQYDV 131 Query: 138 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSHFQAEEEFVLEPGDMLYLPPHYAHDG 194 F++Q G+RRWR+ + L + + P L + F+A + LEPGD+LY+PP + H+G Sbjct: 132 FIIQGTGRRRWRVG--EKLQMRQHCPHPDLLQVEPFEAIIDEELEPGDILYIPPGFPHEG 189 Query: 195 VAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYADPDLKTSARPAELQADMIAR 254 A+ M YS+GFRAP +EL F ++++ Y+DPD+ + PA++ + + Sbjct: 190 YALENAMNYSVGFRAPNSRELISGFADYVLQRELGNTYYSDPDMPSRKHPADILPQEMDK 249 Query: 255 IRDELNKIRFTDDDITIFLGQHLSEPKPSVFFEAPPQELSFARFFQGTKKRGLVLHR--K 312 +R+ + + +LG+ LS+ + + APP+ K+G VL R Sbjct: 250 LRNMMLDLINQPAHFQQWLGEFLSQSRHELDI-APPEPPYQPDEIYDALKQGEVLVRLGG 308 Query: 313 TRMLYRGSHVFINGESFQVSRQDKAILARLADHRMLEKNDFDQASED 359 R+L G V+ NGE ++ + L LA H L +F A ED Sbjct: 309 LRVLRIGDEVYANGE--KIDSPHRPALEALASHIALTAENFGDALED 353 >ycfD [S] COG2850 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 376 Score = 213 bits (542), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 124/347 (35%), Positives = 194/347 (55%), Gaps = 10/347 (2%) Query: 18 FLRDYWHKKPLLIRNAIPGFSAPLPRQELFDLARRDDVESRLITHREGGWDMQHGPFNKL 77 FL +W K+P++++ F P+ EL LA +V+SRL++H++G W + HGPF Sbjct: 15 FLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESY 74 Query: 78 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYASDGGGVGPHFDSYDV 137 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 75 DHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDV 134 Query: 138 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSHFQAEEEFVLEPGDMLYLPPHYAHDG 194 F++Q G+RRWR+ + L +++ P L + F+A + LEPGD+LY+PP + H+G Sbjct: 135 FIIQGTGRRRWRVGEK--LQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEG 192 Query: 195 VAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYADPDLKTSARPAELQADMIAR 254 A+ M YS+GFRAP +EL F ++++ Y+DPD+ A PA++ + + Sbjct: 193 YALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDK 252 Query: 255 IRDELNKIRFTDDDITIFLGQHLSEPKPSVFFEAPPQELSFARFFQGTKKRGLVLHR--K 312 +R+ + ++ + + G+ +S+ + + APP+ K+G VL R Sbjct: 253 LREMMLELINQPEHFKQWFGEFISQSRHELDI-APPEPPYQPDEIYDALKQGEVLVRLGG 311 Query: 313 TRMLYRGSHVFINGESFQVSRQDKAILARLADHRMLEKNDFDQASED 359 R+L G V+ NGE ++ + L LA + L +F A ED Sbjct: 312 LRVLRIGDDVYANGE--KIDSPHRPALDALASNIALTAENFGDALED 356 >ZycfD [S] COG2850 Uncharacterized conserved protein EcZ Escherichia coli O157:H7 EDL933 Length = 376 Score = 213 bits (541), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 124/347 (35%), Positives = 194/347 (55%), Gaps = 10/347 (2%) Query: 18 FLRDYWHKKPLLIRNAIPGFSAPLPRQELFDLARRDDVESRLITHREGGWDMQHGPFNKL 77 FL +W K+P++++ F P+ EL LA +V+SRL++H++G W + HGPF Sbjct: 15 FLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESY 74 Query: 78 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYASDGGGVGPHFDSYDV 137 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 75 DHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDV 134 Query: 138 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSHFQAEEEFVLEPGDMLYLPPHYAHDG 194 F++Q G+RRWR+ + L +++ P L + F+A + LEPGD+LY+PP + H+G Sbjct: 135 FIIQGTGRRRWRVGEK--LQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEG 192 Query: 195 VAVGECMTYSIGFRAPTYQELGESFLEFMMDTIDLPGRYADPDLKTSARPAELQADMIAR 254 A+ M YS+GFRAP +EL F ++++ Y+DPD+ A PA++ + + Sbjct: 193 YALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDK 252 Query: 255 IRDELNKIRFTDDDITIFLGQHLSEPKPSVFFEAPPQELSFARFFQGTKKRGLVLHR--K 312 +R+ + ++ + + G+ +S+ + + APP+ K+G VL R Sbjct: 253 LREMMLELINQPEHFKQWFGEFISQSRHELDI-APPEPPYQPDEIYDALKQGDVLVRLGG 311 Query: 313 TRMLYRGSHVFINGESFQVSRQDKAILARLADHRMLEKNDFDQASED 359 R+L G V+ NGE ++ + L LA + L +F A ED Sbjct: 312 LRVLRIGDDVYTNGE--KIDSPHRPALDALASNIALTAENFGDALED 356