BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0131.p (222 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1984 [E] COG0135 Phosphoribosylanthranilate isomerase Rso Ral... 252 4e-67 PA3113 [E] COG0135 Phosphoribosylanthranilate isomerase Pae Pseu... 181 1e-45 NMA0890 [E] COG0135 Phosphoribosylanthranilate isomerase NmA Nei... 161 1e-39 TM0139 [E] COG0135 Phosphoribosylanthranilate isomerase Tma Ther... 160 2e-39 lin1670 [E] COG0135 Phosphoribosylanthranilate isomerase Lin Lis... 157 2e-38 >RSc1984 [E] COG0135 Phosphoribosylanthranilate isomerase Rso Ralstonia solanacearum Length = 230 Score = 252 bits (644), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 133/226 (58%), Positives = 160/226 (70%), Gaps = 16/226 (7%) Query: 3 HRTRIKICGLTREEDVRATVAAGADAMGLVFYPKSPRYVTPERAGELARAVPPFVSIVGL 62 HRTRIK+CGLT+ +DV VA GADA+GLVFYP SPRYV RA ELAR PFV++ GL Sbjct: 4 HRTRIKLCGLTQPDDVDHAVALGADAIGLVFYPPSPRYVATGRAAELARRAGPFVTVTGL 63 Query: 63 FVNPTLDEVQQVLAQAPLTVLQFHGDETPEQCAAIARAVVRPFMRAARIGSSTQPADLLE 122 FVN + D+V +VL Q PLT+LQFHGDETPEQCA IA V P++RA R+ T DL+E Sbjct: 64 FVNASADDVARVLDQVPLTLLQFHGDETPEQCAEIAGKVGLPWLRALRVQPGT---DLVE 120 Query: 123 YEQAYRSASPFFTGLLLDTLVEEYGGSGKVFDWSLIPKEL---------APRAVLSGGLS 173 + + +A GLLLD VE YGG G VFDW+LIP + APR VLSGGLS Sbjct: 121 FADRFAAAQ----GLLLDAFVEGYGGGGHVFDWTLIPPQWLSQSAPPSAAPRLVLSGGLS 176 Query: 174 VHNVTEAVAGVRPYAVDISSGVEAAKGIKDAARIEAFIQAVRLADA 219 NV A+ VRPYAVD+SSG+EAA+G+KD AR+ AF++AVR ADA Sbjct: 177 AQNVAGAIERVRPYAVDVSSGIEAARGVKDRARMTAFVRAVREADA 222 >PA3113 [E] COG0135 Phosphoribosylanthranilate isomerase Pae Pseudomonas aeruginosa Length = 211 Score = 181 bits (459), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 114/212 (53%), Positives = 141/212 (66%), Gaps = 12/212 (5%) Query: 5 TRIKICGLTREEDVRATVAAGADAMGLVFYPKSPRYVTPERAGELARAVPPFVSIVGLFV 64 RIKICG+TR ED A AAGADA+GLVFY KSPR V RA E+ RA+PPFV+ VGLFV Sbjct: 4 VRIKICGITRVEDALAAAAAGADAIGLVFYAKSPRAVDIHRAREIVRALPPFVTSVGLFV 63 Query: 65 NPTLDEVQQVLAQAPLTVLQFHGDETPEQCAAIARAVVRPFMRAARIGSSTQPADLLEYE 124 N + E+ ++L PL +LQFHGDE E C RP+++A R+ +P D + Sbjct: 64 NASRCELGEILDAVPLDLLQFHGDERAEDCEGHR----RPYLKALRM----KPGDDIVGR 115 Query: 125 QAYRSASPFFTGLLLDTLVEEY-GGSGKVFDWSLIPKELAPRAVLSGGLSVHNVTEAVAG 183 A A P G+LLDT VE GG+G FDWSL+P +L VL+GGL+ NV AV Sbjct: 116 AA---AYPGAAGILLDTYVEGVPGGTGAAFDWSLVPTDLGKPLVLAGGLTPDNVGRAVEQ 172 Query: 184 VRPYAVDISSGVEAAKGIKDAARIEAFIQAVR 215 V+PYAVD+S GVEA+KGIKDAAR+ AF+ AVR Sbjct: 173 VKPYAVDVSGGVEASKGIKDAARVRAFVDAVR 204 >NMA0890 [E] COG0135 Phosphoribosylanthranilate isomerase NmA Neisseria meningitidis Z2491 Length = 208 Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 90/212 (42%), Positives = 128/212 (60%), Gaps = 18/212 (8%) Query: 4 RTRIKICGLTREEDVRATVAAGADAMGLVFYPKSPRYVTPERAGELARAVPPFVSIVGLF 63 + R KICG+T ED AGADA+GLVFYP+SPR V +A ++ A+PPFVS+V LF Sbjct: 3 KIRTKICGITTPEDALYAAHAGADALGLVFYPQSPRAVDIIKAQKITAALPPFVSVVALF 62 Query: 64 VNPTLDEVQQVLAQAPLTVLQFHGDETPEQCAAIARAVVRPFMRAARIGSSTQPADLLEY 123 VN + ++++LA+ P+ ++QFHGDE C R RP+++A R+ +++ Sbjct: 63 VNESAQNIRRILAEVPIHIIQFHGDEDDAFC----RQFHRPYIKAIRVQTASD------- 111 Query: 124 EQAYRSASPFF---TGLLLDTLV-EEYGGSGKVFDWSLIPKELAPRAVLSGGLSVHNVTE 179 R+A+ F LL D EYGG+G FDW+L+ + VL+GGL+ NV E Sbjct: 112 ---IRNAADRFPDAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGGLTPENVDE 168 Query: 180 AVAGVRPYAVDISSGVEAAKGIKDAARIEAFI 211 A+ AVD+S GVEA+KG KD A++ AFI Sbjct: 169 AIRITGAEAVDVSGGVEASKGKKDPAKVAAFI 200 >TM0139 [E] COG0135 Phosphoribosylanthranilate isomerase Tma Thermotoga maritima Length = 205 Score = 160 bits (405), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 91/213 (42%), Positives = 125/213 (58%), Gaps = 13/213 (6%) Query: 5 TRIKICGLTREEDVRATVAAGADAMGLVFYPKSPRYVTPERAGELARAVPPFVSIVGLFV 64 R+KICG+T ED +V +GADA+G VFYPKS RY++PE A ++ +PPFV VG+FV Sbjct: 2 VRVKICGITNLEDALFSVESGADAVGFVFYPKSKRYISPEDARRISVELPPFVFRVGVFV 61 Query: 65 NPTLDEVQQVLAQAPLTVLQFHGDETPEQCAAIARAVVRPFMRAARIGSSTQPADLLEYE 124 N +++ V + L +Q HG+E E C IA ++ ++A + + L Y Sbjct: 62 NEEPEKILDVASYVQLNAVQLHGEEPIELCRKIAERIL--VIKAVGVSNERDMERALNYR 119 Query: 125 QAYRSASPFFTGLLLDTLVEEYGGSGKVFDWSLI--PKELAPRAVLSGGLSVHNVTEAVA 182 + +LLDT EYGGSGK FDWSLI ++ VLSGGL+ NV A+ Sbjct: 120 E---------FPILLDTKTPEYGGSGKTFDWSLILPYRDRFRYLVLSGGLNPENVRSAID 170 Query: 183 GVRPYAVDISSGVEAAKGIKDAARIEAFIQAVR 215 VRP+AVD+SSGVEA G KD I+ FI+ + Sbjct: 171 VVRPFAVDVSSGVEAFPGKKDHDSIKMFIKNAK 203 >lin1670 [E] COG0135 Phosphoribosylanthranilate isomerase Lin Listeria innocua Length = 203 Score = 157 bits (397), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 89/213 (41%), Positives = 125/213 (58%), Gaps = 20/213 (9%) Query: 7 IKICGLTREEDVRATVAAGADAMGLVFYPKSPRYVTPERAGELARAVPPFVSIVGLFVNP 66 +KICGL + DV+A V GAD +G VF KS R VT E+A +LA+ +PP + VG+FVNP Sbjct: 3 VKICGLKKSVDVKAAVENGADMIGFVF-AKSKRQVTIEQAHQLAKNIPPNIKKVGVFVNP 61 Query: 67 TLDEVQQVLAQAPLTVLQFHGDETPEQCAAIARAVVRPF-MRAARIGSSTQPADLLEYEQ 125 T DE+ + PL ++Q HG E EQ V++ F ++ ++ P ++ +Y Sbjct: 62 TEDELTAAIKGVPLDIVQLHGQEPTEQADRTDAEVIKAFPVKEGKL-----PNNINDYSN 116 Query: 126 AYRSASPFFTGLLLDTLVEEY-GGSGKVFDWSLIPKEL--APRAVLSGGLSVHNVTEAVA 182 AY +LLD EEY GGSGK FDW + +L + +++GGL+V NV EA+ Sbjct: 117 AY---------ILLDAPAEEYEGGSGKTFDWDKVNSDLLIKNKLIIAGGLNVENVKEAIN 167 Query: 183 GVRPYAVDISSGVEAAKGIKDAARIEAFIQAVR 215 PYAVDISSGVE G KD +I+ FI+ + Sbjct: 168 RFEPYAVDISSGVE-TNGEKDPEKIKIFIKTAK 199