BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0116.p (438 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1559 [S] COG1295 Predicted membrane protein Rso Ralstonia sol... 288 2e-77 NMB0524 [S] COG1295 Predicted membrane protein Nme Neisseria men... 194 2e-49 NMA0700 [S] COG1295 Predicted membrane protein NmA Neisseria men... 194 4e-49 STM4027 [S] COG1295 Predicted membrane protein Sty Salmonella ty... 188 2e-47 YPO0028 [S] COG1295 Predicted membrane protein Ype Yersinia pestis 185 2e-46 >RSc1559 [S] COG1295 Predicted membrane protein Rso Ralstonia solanacearum Length = 441 Score = 288 bits (736), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 148/288 (51%), Positives = 200/288 (69%) Query: 1 VAGSLTFTTILSLVPMLTIALALFTAFPLFSTFRASLEAYFVENLMPKGVANTILGYLNQ 60 VAGSLTFTT+LSLVP+LT+A ALFTAFP+F +FRA++E Y NL+P ++ IL YLNQ Sbjct: 35 VAGSLTFTTVLSLVPILTVAFALFTAFPMFQSFRAAIEGYLFSNLVPGNISRPILTYLNQ 94 Query: 61 FAAKSARISAVGGVVLILTSVLTMSTIESVFNQIWRVKKSRPLVQRVLVYWAIITLGPLL 120 F+ + ++A G V L++TSV+TM T+E+ N IWRV++ RPL QRVLV+WA+++ GP+L Sbjct: 95 FSHNAKGLTAAGLVGLVVTSVMTMLTVENALNAIWRVRQRRPLAQRVLVFWALVSFGPVL 154 Query: 121 IGVSISVTSYLSTATGGAVKSLPWLGASFYTLVSLMFSTLAYTLLYSTVPNQTVDWRDAL 180 IG S+SV+SYL + + G V LP+ LV ++ S +A+ +LY VPN V WRDA Sbjct: 155 IGASLSVSSYLVSVSAGYVAKLPYGLGVVVGLVPILLSAIAFAMLYVFVPNTLVAWRDAF 214 Query: 181 AGGLLAGIGLEIAKRLFAVYILKFPTYTMVYGTVAVLPIFLVWIYMMWMITLFGALLTAA 240 GL+A + EIAKR F Y+ +FPTYT VYGT A LPIFL+WIY+ W++TL GA + A Sbjct: 215 LAGLVAAVAFEIAKRGFGYYVARFPTYTAVYGTFAALPIFLLWIYVSWLVTLLGATIAAT 274 Query: 241 LPVVRYERWWHVASPGAEFIDAIKVLRFLHAARVGVESAVVSMDEVRR 288 LP++R W A PG+EF DA+ +L LH AR + +D RR Sbjct: 275 LPIIRQGYWQRRAFPGSEFFDALGILLLLHRARDHAPRTLGELDIGRR 322 >NMB0524 [S] COG1295 Predicted membrane protein Nme Neisseria meningitidis MC58 Length = 406 Score = 194 bits (494), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 128/384 (33%), Positives = 207/384 (53%), Gaps = 29/384 (7%) Query: 2 AGSLTFTTILSLVPMLTIALALFTAFPLFSTFRASLEAYFVENLMPKGVANTILGYLNQF 61 A S+TFTT+L+LVP+LT+ +A+ + FP+F + S ++ + ++P+G A+ + Y+N F Sbjct: 35 AASMTFTTLLALVPVLTVMVAVASIFPVFDRWSDSFVSFVNQTIVPQG-ADMVFDYINAF 93 Query: 62 AAKSARISAVGGVVLILTSVLTMSTIESVFNQIWRVKKSRPLVQRVLVYWAIITLGPLLI 121 ++ R++A+G V+L++TS++ + TI++ FN+IWRV RP + + LVYWA++T GPL + Sbjct: 94 REQANRLTAIGSVMLVVTSLMLIRTIDNTFNRIWRVNSQRPWMMQFLVYWALLTFGPLSL 153 Query: 122 GVSISVTSYLSTATGGAVKSLPWLGASFYTLVSLMFSTLAYTLLYSTVPNQTVDWRDALA 181 GV IS A + W GA T +L F TL LY VPN+ V R A Sbjct: 154 GVGISFMVGSVQDAALASGAPQWSGA-LRTAATLTFMTLLLWGLYRFVPNRFVPARQAFV 212 Query: 182 GGLLAGIGLEIAKRLFAVYILKFPTYTMVYGTVAVLPIFLVWIYMMWMITLFGALLTAAL 241 G L LE A+ LF Y+ F Y +YG A +P FL+W+ ++W + L GA+LT++L Sbjct: 213 GALATAFCLETARSLFTWYMGNFDGYRSIYGAFAAVPFFLLWLNLLWTLVLGGAVLTSSL 272 Query: 242 PVVRYERWWHVASPGAEFIDAIKVLRFLHAARVGVESAVVSMDEVRRATRLGLGELQQLL 301 + E + F D +K+L L AA+ E + + E RR +G EL +LL Sbjct: 273 SYWQGEAFRRGFDSRGRFDDVLKILLLLDAAQ--KEGKALPVQEFRRHINMGYDELGELL 330 Query: 302 ARMSEEGWVASVKPGNSRRSSWNRRITDDMDRWTLVANPSTIQLARVYRLFVFDPAVLAQ 361 +++ G++ S + G W L +I+L +++LFV+ P + + Sbjct: 331 EKLARHGYIYSGRQG-----------------WVLKTGADSIELNELFKLFVYRPLPVER 373 Query: 362 AGEEEGLVHRVEGAIDAVLAQSLE 385 V A+DAV+ L+ Sbjct: 374 --------DHVNQAVDAVMTPCLQ 389 >NMA0700 [S] COG1295 Predicted membrane protein NmA Neisseria meningitidis Z2491 Length = 408 Score = 194 bits (493), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 128/384 (33%), Positives = 207/384 (53%), Gaps = 29/384 (7%) Query: 2 AGSLTFTTILSLVPMLTIALALFTAFPLFSTFRASLEAYFVENLMPKGVANTILGYLNQF 61 A S+TFTT+L+LVP+LT+ +A+ + FP+F + S ++ + ++P+G A+ + Y+N F Sbjct: 35 AASMTFTTLLALVPVLTVMVAVASIFPVFDRWSDSFVSFVNQTIVPQG-ADMVFDYINAF 93 Query: 62 AAKSARISAVGGVVLILTSVLTMSTIESVFNQIWRVKKSRPLVQRVLVYWAIITLGPLLI 121 ++ R++A+G V+L++TS++ + TI++ FN+IWRV RP + + LVYWA++T GPL + Sbjct: 94 REQANRLTAIGSVMLVVTSLMLIRTIDNTFNRIWRVNSQRPWMMQFLVYWALLTFGPLSL 153 Query: 122 GVSISVTSYLSTATGGAVKSLPWLGASFYTLVSLMFSTLAYTLLYSTVPNQTVDWRDALA 181 GV IS A + W GA T +L F TL LY VPN+ V R A Sbjct: 154 GVGISFMVGSVQDAALASGAPQWSGA-LRTAATLTFMTLLLWGLYRFVPNRFVPARQAFV 212 Query: 182 GGLLAGIGLEIAKRLFAVYILKFPTYTMVYGTVAVLPIFLVWIYMMWMITLFGALLTAAL 241 G L LE A+ LF Y+ F Y +YG A +P FL+W+ ++W + L GA+LT++L Sbjct: 213 GALATAFCLETARSLFTWYMGNFDGYRSIYGAFAAVPFFLLWLNLLWTLVLGGAVLTSSL 272 Query: 242 PVVRYERWWHVASPGAEFIDAIKVLRFLHAARVGVESAVVSMDEVRRATRLGLGELQQLL 301 + E + F D +K+L L AA+ E + + E RR +G EL +LL Sbjct: 273 SYWQGEAFRRGFDSRGRFDDVLKILLLLDAAQ--KEGKALPVQEFRRHINMGYDELGELL 330 Query: 302 ARMSEEGWVASVKPGNSRRSSWNRRITDDMDRWTLVANPSTIQLARVYRLFVFDPAVLAQ 361 +++ G++ S + G W L +I+L +++LFV+ P + + Sbjct: 331 EKLARHGYIYSGRQG-----------------WVLKTGADSIELNELFKLFVYRPLPVER 373 Query: 362 AGEEEGLVHRVEGAIDAVLAQSLE 385 V A+DAV+ L+ Sbjct: 374 --------DHVNQAVDAVMMPCLQ 389 >STM4027 [S] COG1295 Predicted membrane protein Sty Salmonella typhimurium LT2 Length = 290 Score = 188 bits (477), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 103/250 (41%), Positives = 146/250 (58%), Gaps = 21/250 (8%) Query: 1 VAGSLTFTTILSLVPMLTIALALFTAFPLFSTFRASLEAYFVENLMPKGVANTILGYLNQ 60 +AG+L + ++LSLVP++ + ALF AFP+FS L + N MP + I Y+ Q Sbjct: 35 LAGNLAYVSLLSLVPLIAVVFALFAAFPMFSDVSIQLRHFIFANFMP-ATGDVIQRYIEQ 93 Query: 61 FAAKSARISAVGGVVLILTSVLTMSTIESVFNQIWRVKKSRPLVQRVLVYWAIITLGPLL 120 F A S +++AVG LI+T++L M I+S N IWR K++RP V VYW I+TLGPLL Sbjct: 94 FVANSNKMTAVGACGLIVTALLLMYAIDSALNTIWRSKRTRPKVYSFAVYWMILTLGPLL 153 Query: 121 IGVSISVTSYL---------STATGGAVKSLPWLGASFYTLVSLMFSTLAYTLLYSTVPN 171 GVS++++SYL +T + LP L+ S +++ LLYS VP Sbjct: 154 AGVSLAISSYLLSLRWASDLNTVIDNVLHILP-----------LLLSWISFWLLYSIVPT 202 Query: 172 QTVDWRDALAGGLLAGIGLEIAKRLFAVYILKFPTYTMVYGTVAVLPIFLVWIYMMWMIT 231 V RDAL G +A + E K+ FA+YI FP+Y ++YG +AV+PI VW+Y W I Sbjct: 203 TRVPNRDALVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIV 262 Query: 232 LFGALLTAAL 241 L GA +T L Sbjct: 263 LLGAEITVTL 272 >YPO0028 [S] COG1295 Predicted membrane protein Ype Yersinia pestis Length = 294 Score = 185 bits (469), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 102/248 (41%), Positives = 151/248 (60%), Gaps = 1/248 (0%) Query: 1 VAGSLTFTTILSLVPMLTIALALFTAFPLFSTFRASLEAYFVENLMPKGVANTILGYLNQ 60 +AG L + ++LSLVP++T+ ALF AFP+F+ L+A+ N MP + I YL Q Sbjct: 35 LAGHLAYVSLLSLVPLITVIFALFAAFPMFAEISIKLKAFIFANFMP-ATGDIIQNYLEQ 93 Query: 61 FAAKSARISAVGGVVLILTSVLTMSTIESVFNQIWRVKKSRPLVQRVLVYWAIITLGPLL 120 F A S R++ VG LI+T++L + +++SV N IWR K R LV VYW ++TLGP+L Sbjct: 94 FVANSNRMTVVGTCGLIVTALLLIYSVDSVLNIIWRSKIQRSLVFSFAVYWMVLTLGPIL 153 Query: 121 IGVSISVTSYLSTATGGAVKSLPWLGASFYTLVSLMFSTLAYTLLYSTVPNQTVDWRDAL 180 +G S+ ++SYL + A + + + L+ S +++ LLYS VP V RDAL Sbjct: 154 VGASMVISSYLLSLHWLAHARVDSMIDEILRVFPLLISWVSFWLLYSVVPTVRVPARDAL 213 Query: 181 AGGLLAGIGLEIAKRLFAVYILKFPTYTMVYGTVAVLPIFLVWIYMMWMITLFGALLTAA 240 G L+A + E+ K+ FA+YI FP+Y ++YG +AV+PI +W+Y W I L GA +T Sbjct: 214 IGALVAALLFELGKKGFAMYITLFPSYQLIYGVLAVIPILFLWVYWSWCIVLLGAEITVT 273 Query: 241 LPVVRYER 248 L R ER Sbjct: 274 LGEYRAER 281