BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0083.p (498 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2009 [S] COG3333 Uncharacterized protein conserved in bacteria... 317 5e-86 FN2105 [S] COG3333 Uncharacterized protein conserved in bacteria... 281 3e-75 PM1681 [S] COG3333 Uncharacterized protein conserved in bacteria... 276 9e-74 PA2207 [S] COG3333 Uncharacterized protein conserved in bacteria... 262 2e-69 SMc00500 Non COG 257 4e-68 >BH2009 [S] COG3333 Uncharacterized protein conserved in bacteria Bha Bacillus halodurans Length = 504 Score = 317 bits (811), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 168/468 (35%), Positives = 275/468 (58%), Gaps = 2/468 (0%) Query: 1 MFANIYAAFGMVFDPYVLAVILGSSIFGLFMGAVPGLSATMAVALLVPVTFFMPPVPAIA 60 M + + VF+ L +L I G+ +G +PGLS T+A+AL++P TF MP A+ Sbjct: 1 MMEHFFYGLTQVFEWQNLLYMLLGVIAGIVVGGLPGLSVTIALALMLPFTFGMPASTAML 60 Query: 61 AMVSATAMAIFSGDIPGCLLRIPGTPSSAAYTDEAYAMTMKGQGEIALGASLVFSVIGGL 120 M+ + G I LL+ PGTP+SAA + +A++ +G+ AL SL SVIGGL Sbjct: 61 LMLGVYCAGTYGGSIGAILLKTPGTPASAATAADGFALSQQGKAGRALNISLYASVIGGL 120 Query: 121 FGTFVLILAAPALAELALKFSSFEYFWLVLLGLTCAIFIASDNPLKGFVSLFLGMFIASI 180 VL+ +P +A ALKF EYF L L GLT ++ + +KG ++ GM IA+I Sbjct: 121 VSGLVLLFVSPQIASFALKFGPPEYFMLALFGLTIVAGVSGQSLIKGLITACFGMLIATI 180 Query: 181 GMGNPAGAPRFTFDQPDLLGGVSLVPLMVGMFAMSEVLRFAVSRDFSMKVAESRVGNVFK 240 G+ G+PRFTF+Q L G+ L+P ++G+FA+SE++ + R + A + F Sbjct: 181 GLDPMTGSPRFTFEQTFLQSGIPLIPALIGLFAISEIMNQSAKRREKISTAVNFQHERFG 240 Query: 241 GMWGLMLKYPKSVLRGSVLGTLVGALPGAGADIAAWMSYAMSKKLSKEPEKFGTGHPEGI 300 W M + K++++ S +G ++GA+PG G IA+++S ++++SK+P++FG G E + Sbjct: 241 --WKHMFPFRKTIIKSSFIGVIIGAIPGTGGSIASFLSVNEAQRVSKKPKEFGNGSEESV 298 Query: 301 VESGAANNSALAGAWIPALVFGIPGDSITAIVIGVLYMKNLNPGPMIFVENPVSMYAIFI 360 + A NN IP + G+PGD ITA+++ L ++ L PGP +F + +Y + + Sbjct: 299 AAAEAGNNGTTGATLIPMMTLGVPGDVITAVLLSALLIQGLQPGPQLFQSHGDLVYTVMV 358 Query: 361 VFILANLLMLPLGFWCIKMAKRILSIPRGILMPLILLFCIVGSYATNNSVTDVGIMLVFG 420 FI+ N++M +G I+ ++ +P +L P++L+FC++GSYA N S V I +VFG Sbjct: 359 GFIVVNIIMFIVGKLAIRWFAKVTILPSSVLFPVVLMFCLIGSYAYNYSFHSVWIAIVFG 418 Query: 421 LLAYVMEENGFPVAPAVLGVVLGGMLEEHFVTSMIKADGQFLAFFERP 468 L+ Y++ + GFPV P ++G++LG M E +++ ++G F ERP Sbjct: 419 LIGYMLPKFGFPVIPILIGMILGPMAERSLRQALVLSEGSLFIFIERP 466 >FN2105 [S] COG3333 Uncharacterized protein conserved in bacteria Fnu Fusobacterium nucleatum Length = 494 Score = 281 bits (719), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 179/500 (35%), Positives = 281/500 (56%), Gaps = 17/500 (3%) Query: 3 ANIYAAFGMVFDPYVLAVILGSSIFGLFMGAVPGLSATMAVALLVPVTFFMPPVPAIAAM 62 +++ + P L + S G+ +GA+PGLSA M VALL+P+TF M P + + Sbjct: 2 SDVLFGYAAALTPINLVAAVISVTIGITIGALPGLSAAMGVALLIPITFGMDPSTGLITL 61 Query: 63 VSATAMAIFSGDIPGCLLRIPGTPSSAAYTDEAYAMTMKGQGEIALGASLVFSVIGGLFG 122 AIF G I L+R PGTP++AA + Y +T +G+ ALG +++ S IGG+ Sbjct: 62 AGVYCGAIFGGSISAILIRTPGTPAAAATAIDGYELTKQGKAGTALGTAIIASFIGGILS 121 Query: 123 TFVLILAAPALAELALKFSSFEYFWLVLLGLTCAIFIASDNPLKGFVSLFLGMFIASIGM 182 L L AP LA+LAL F EYFWL + GLT ++ + +KG +S LG+ ++++GM Sbjct: 122 AIPLYLFAPRLAKLALLFGPAEYFWLSIFGLTIIAGASTKSIVKGLISGALGLMLSTVGM 181 Query: 183 GNPAGAPRFTFDQPDLLGGVSLVPLMVGMFAMSEVLRFAVSR--------DFSMKVAESR 234 G PRFTF P LL G+ ++G+F+MS+VL A + +F KV S+ Sbjct: 182 DPMLGNPRFTFGVPALLSGIPFTAALIGLFSMSQVLMLAEKKIKQAGNMVEFDNKVLLSK 241 Query: 235 VGNVFKGMWGLMLKYPKSVLRGSVLGTLVGALPGAGADIAAWMSYAMSKKLSKEPEKFGT 294 +L+ + LR +V+G+++G LPGAGA IAA++ Y +K+ SK+ E FG Sbjct: 242 ---------KQILEILPTSLRSTVIGSIIGILPGAGASIAAFLGYNEAKRFSKKKELFGH 292 Query: 295 GHPEGIVESGAANNSALAGAWIPALVFGIPGDSITAIVIGVLYMKNLNPGPMIFVENPVS 354 G EGI S AANN+ G+ IP GIPG+S+TA+++G L ++ L PGP +F + Sbjct: 293 GSIEGIAGSEAANNAVTGGSLIPTFTLGIPGESVTAVLLGGLMIQGLQPGPDLFTVHGKI 352 Query: 355 MYAIFIVFILANLLMLPLGFWCIKMAKRILSIPRGILMPLILLFCIVGSYATNNSVTDVG 414 Y F F++ N+ ML LG + K+ R+ I L+PLI ++GSYA +N ++DV Sbjct: 353 TYTFFAGFVIVNIFMLILGLFGSKLFARVSRISDSYLIPLIFSLSVIGSYAIHNQMSDVW 412 Query: 415 IMLVFGLLAYVMEENGFPVAPAVLGVVLGGMLEEHFVTSMIKADGQFLAFFERPIAGTLG 474 +M VFG++ Y +++ A VL ++LG + E S+I + F+ ++ L Sbjct: 413 VMFVFGIIGYFVQKFELNSASIVLALILGPIGESGLRRSLILNHNNYSILFQSTVSKVLL 472 Query: 475 VITLLLWLLPLALKLLRRKT 494 ++TL P+ + L++++ Sbjct: 473 LLTLFSLFSPIIMSKLKKRS 492 >PM1681 [S] COG3333 Uncharacterized protein conserved in bacteria Pmu Pasteurella multocida Length = 498 Score = 276 bits (706), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 171/477 (35%), Positives = 275/477 (57%), Gaps = 12/477 (2%) Query: 1 MFANIYAAFGMVFDPYVLAVILGSSIFGLFMGAVPGLSATMAVALLVPVTFFMPPVPAIA 60 MF I A F F I G+ G++PGL+ + + L +P+T+ + + + Sbjct: 1 MFDQIIAGFNEFFTWGSFLYINLGLFLGIVFGSIPGLTVMLCLVLFLPITYSLNAIHSFM 60 Query: 61 AMVSATAMAIFSGDIPGCLLRIPGTPSSAAYTDEAYAMTMKGQGEIALGASLVFSVIGGL 120 ++ + G I L++ PGTP +AA + + +G + AL +L S +GG+ Sbjct: 61 FLLGIYCAGSYGGSISAILIKTPGTPHAAATMLDGNPLANRGMAQKALNVALYASFVGGI 120 Query: 121 FGTFVLILAAPALAELALKFSSFEYFWLVLLGLTCAIFIASDNPLKGFVSLFLGMFIASI 180 VL+ AP +A++ALK S EYF + GLT ++ ++ LKG +S LG+F++ I Sbjct: 121 VSALVLLFLAPEVAKVALKMGSPEYFLICAFGLTIIAGVSGESLLKGIISGCLGLFLSFI 180 Query: 181 GMGNPAGAP-RFTFDQPDLLGGVSLVPLMVGMFAMSEVLRFAVSRDF----SMKVAESRV 235 GM +G+ RF FD +L GG LV +++G+FA+ E++ RD + +V ++ Sbjct: 181 GMDLISGSTMRFAFDNINLYGGFDLVVVLIGLFALIEIIN--KGRDLKSHGNKQVEPPKL 238 Query: 236 --GNVFKGMWGLMLKYPKSVLRGSVLGTLVGALPGAGADIAAWMSYAMSKKLSKEPEKFG 293 G V K W L+ PK + GS+ G LVG +PG GA IA+++SY S+K+SK+PE+FG Sbjct: 239 DKGTVSKSEW---LRLPKPLAIGSLSGILVGIIPGTGASIASFLSYDFSRKVSKKPEEFG 295 Query: 294 TGHPEGIVESGAANNSALAGAWIPALVFGIPGDSITAIVIGVLYMKNLNPGPMIFVENPV 353 G EGI + ANN+ A +P L GIPGD+ A+++G L + L PGP +F + Sbjct: 296 KGSVEGIAAAECANNAITGTALVPLLTLGIPGDAAVALMLGALMINGLTPGPNLFQNHGT 355 Query: 354 SMYAIFIVFILANLLMLPLGFWCIKMAKRILSIPRGILMPLILLFCIVGSYATNNSVTDV 413 ++YAI I I N+ ML G + +K +++ IP+ IL+P+I +FC G+Y+ S+ DV Sbjct: 356 AVYAIMIGLIFVNIFMLIQGKYLLKFFAKVVKIPQQILIPIIAVFCFAGAYSLKESMFDV 415 Query: 414 GIMLVFGLLAYVMEENGFPVAPAVLGVVLGGMLEEHFVTSMIKADGQFLAFFERPIA 470 G LVFG++AY+M++ GF P +LG+VLG + E++ +++ +DG + F ERP + Sbjct: 416 GAALVFGIIAYLMDKLGFSAVPTLLGLVLGALTEKNLRRALLISDGDWTLFLERPFS 472 >PA2207 [S] COG3333 Uncharacterized protein conserved in bacteria Pae Pseudomonas aeruginosa Length = 506 Score = 262 bits (669), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 174/496 (35%), Positives = 276/496 (55%), Gaps = 7/496 (1%) Query: 2 FANIYAAFGMVFDPYVLAVILGSSIFGLFMGAVPGLSATMAVALLVPVTFFMPPVPAIAA 61 F ++ +V + L +++ + G+ +G +PGL A VALL+P+TF M PV AI Sbjct: 4 FDSLMQGMSLVLSAHHLGLMVIGVLLGILVGVLPGLGAPNGVALLLPLTFSMSPVSAIIL 63 Query: 62 MVSATAMAIFSGDIPGCLLRIPGTPSSAAYTDEAYAMTMKGQGEIALGASLVFSVIGGLF 121 + A+F G I L IPG PSS A T + Y M GQ AL A+ +++G L Sbjct: 64 LSCMYWGALFGGSITSILFNIPGEPSSVATTFDGYPMARNGQAGEALTAAFTSALLGALV 123 Query: 122 GTFVLILAAPALAELALKFSSFEYFWLVLLGLTCAIFIASDNPLKGFVSLFLGMFIASIG 181 G +L + +A AL FSS E+F + LL I ++ + PLK V++ +G +A++G Sbjct: 124 GVLLLTFLSTHIARFALAFSSPEFFAVYLLAFCTFIGMSRNPPLKTLVAMTIGFAMAAVG 183 Query: 182 MGNPAGAPRFTFDQPDLLGGVSLVPLMVGMFAMSEVLRFAVSRDFSMKVAESRVGN-VFK 240 M +G R TFDQP LL G+S ++G+F + E+L V + +R+ V Sbjct: 184 MDTVSGDLRLTFDQPWLLSGLSFELAVIGLFGIGEIL-CTVEEGLVFRGERARITPMVIL 242 Query: 241 GMWGLMLKYPKSVLRGSVLGTLVGALPGAGADIAAWMSYAMSKKLSKEPEKFGTGHPEGI 300 W + +Y + LR +++G +G PG G A++MSY+++++ SK E FG G EG+ Sbjct: 243 RTWARLPRYWLTWLRSALVGCWMGVTPG-GPTAASFMSYSLARRFSKNRENFGNGEVEGV 301 Query: 301 VESGAANNSALAGAWIPALVFGIPGDSITAIVIGVLYMKNLNPGPMIFVENPVSMYAIFI 360 + A++SA A +P L GIPG + A+++G L + L+PGP +FVE ++ + Sbjct: 302 IAPETADHSAGTSALLPMLTLGIPGSATAAVMLGGLMIWGLHPGPTLFVEQHDFVWGLIA 361 Query: 361 VFILANLLMLPLGFWCIKMAKRILSIPRGILMPLILLFCIVGSYATNNSVTDVGIMLVFG 420 L N++ L + + + IL IP I+ P+I++ C +G+Y+ +N++ DV +ML+FG Sbjct: 362 SMYLGNVVSLIVVLATVPLFASILRIPFAIVAPIIVMVCAIGAYSVHNAMLDVVLMLLFG 421 Query: 421 LLAYVMEENGFPVAPAVLGVVLGGMLEEHFVTSMIKADGQFLAFFERP-IAGTLG-VITL 478 L Y+ ++ G+P+AP VL VLG E+ F SM+ +DGQ F+ P +AG G + + Sbjct: 422 ALGYLFKKLGYPIAPLVLAAVLGDKAEDAFRQSMLFSDGQLSVFWSNPLVAGLTGAALAM 481 Query: 479 LLW--LLPLALKLLRR 492 LLW L A L RR Sbjct: 482 LLWPLLARCAGALFRR 497 >SMc00500 Non COG Length = 505 Score = 257 bits (657), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 173/490 (35%), Positives = 283/490 (57%), Gaps = 9/490 (1%) Query: 5 IYAAFGMVFDPYVLAVILGSSIFGLFMGAVPGLSATMAVALLVPVTFFMPPVPAIAAMVS 64 I + G++F +AV++ ++ G+ +GA+PGL ++ ++LL+P T+ + P ++ M+S Sbjct: 4 ILQSLGVIFSLSGVAVLVTGALLGIVIGALPGLGPSIGLSLLIPFTYNLGPELSMLLMIS 63 Query: 65 ATAMAIFSGDIPGCLLRIPGTPSSAAYTDEAYAMTMKGQGEIALGASLVFSVIGGLFGTF 124 A + G I LL PGT ++AA + Y+M +G+ A+ SL S +GG+ G Sbjct: 64 LYTSAEYGGSISAILLSTPGTAAAAATAIDGYSMARQGKANEAISISLTASTVGGVLGGL 123 Query: 125 VLILAAPALAELALKFSSFEYFWLVLLGLTCAIFIASDNPLKGFVSLFLGMFIASIGMGN 184 L+L A LA LALKF YF + + GL+ ++ + +KG G+ +A++G+ Sbjct: 124 ALLLLAMPLASLALKFGPAGYFAVGVFGLSSVAALSGGSLVKGLACAAFGLALATVGIDP 183 Query: 185 PAGAPRFTFDQPDLLGGVSLVPLMVGMFAMSEVLRFAVSRDFSMKVAESRVGNVF--KGM 242 AG PRFTF L GV + ++G+FA+SE L SR S + +VG+VF + Sbjct: 184 IAGTPRFTFGLFQLYEGVPFLAALIGLFAVSEALAMVESRVVSAPSIKDKVGHVFMSAAL 243 Query: 243 WGLMLKYPKSVLRGSVLGTLVGALPGAGADIAAWMSYAMSKKLSKEPEKFGTGHPEGIVE 302 W + S+L GSV+GTL+G LPG G +IA W++ ++ + PE+FG G GI Sbjct: 244 WK---ETWHSMLSGSVIGTLLGILPGVGGNIACWVARDYARARDRHPEEFGNGSANGIAA 300 Query: 303 SGAANNSALAGAWIPALVFGIPGDSITAIVIGVLYMKNLNPGPMIFVENPVSMYAIFIVF 362 AANN+ + GA +P L G+PG TAI++G L M L+PGP +F E P +YAI Sbjct: 301 PEAANNATVGGALVPLLALGVPGSPTTAIMVGALIMHGLHPGPQLFNEAPSLVYAILFGT 360 Query: 363 ILANLLMLPLGFWCIKMAKRILSIPRGILMPLILLFCIVGSYATNNSVTDVGIMLVFGLL 422 I+A+L+ G + + R++ +P ++ I+ F ++G++A N + DV +ML FG++ Sbjct: 361 IIASLVQYAAGSLFLPLMARVMRLPDAVIAVGIMAFAVLGAFAIRNLMFDVYLMLGFGVV 420 Query: 423 AYVMEENGFPVAPAVLGVVLGGMLEEHFVTSMIKADGQFLAFFERPIAGTLGVITLLLWL 482 Y+M++ FPVAP +L +VLG ++E ++ T+++ + G + F PI+ +I L+L L Sbjct: 421 GYLMKKLRFPVAPVILAMVLGYLVESNYRTALVSSQGDYTIFVTDPIS----LIFLILSL 476 Query: 483 LPLALKLLRR 492 + L L RR Sbjct: 477 VSLLTPLWRR 486