BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0003.0062.p         (247 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

mhpD [Q] COG3971 2-keto-4-pentenoate hydratase Eco Escherichia c...    62   9e-10
ZmhpD [Q] COG3971 2-keto-4-pentenoate hydratase EcZ Escherichia ...    60   4e-09
Rv3536c [Q] COG3971 2-keto-4-pentenoate hydratase Mtu Mycobacter...    60   5e-09
MT3640 [Q] COG3971 2-keto-4-pentenoate hydratase MtC Mycobacteri...    60   5e-09

>mhpD [Q] COG3971 2-keto-4-pentenoate hydratase Eco Escherichia coli K12
          Length = 271

 Score = 62.4 bits (150), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 53/168 (31%), Positives = 78/168 (46%), Gaps = 20/168 (11%)

Query: 88  LEVELALRVGRDYDPGEQLPDEAELRTVFDAILPAIEVVETRLGHPPCTNPWA-----GM 142
           +E E+AL + RD    +   DE  L    + +LPA+EVV +R+        W+      +
Sbjct: 106 IEAEIALVLNRDLPATDITFDE--LYNAIEWVLPALEVVGSRI------RDWSIQFVDTV 157

Query: 143 ADLQSHGALVTGAPQALPDVLSLRQIEASLSIDGQQVSHTTG----GNPADLWPLLGWLA 198
           AD  S G  V G P   P  L L+     ++ + ++VS   G    G+P +      WLA
Sbjct: 158 ADNASCGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAV---WLA 214

Query: 199 LHCARRGQPWRAGQIITTGSCTGLQMARGGRRVEAALHGIGAVWLDFA 246
              A  G+P R G II TG+   +     G R EA + GIG+V   F+
Sbjct: 215 RKMASLGEPLRTGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFS 262


>ZmhpD [Q] COG3971 2-keto-4-pentenoate hydratase EcZ Escherichia coli
           O157:H7 EDL933
          Length = 269

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 52/161 (32%), Positives = 75/161 (46%), Gaps = 20/161 (12%)

Query: 88  LEVELALRVGRDYDPGEQLPDEAELRTVFDAILPAIEVVETRLGHPPCTNPWA-----GM 142
           +E E+AL + RD    +   DE  L    + +LPA+EVV +R+        W+      +
Sbjct: 104 IEAEIALVLNRDLPATDITFDE--LYNAIEWVLPALEVVGSRI------RDWSIQFVDTV 155

Query: 143 ADLQSHGALVTGAPQALPDVLSLRQIEASLSIDGQQVSHTTG----GNPADLWPLLGWLA 198
           AD  S G  V G P   P  L L+     ++ + ++VS   G    G+P +      WLA
Sbjct: 156 ADNASCGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAV---WLA 212

Query: 199 LHCARRGQPWRAGQIITTGSCTGLQMARGGRRVEAALHGIG 239
              A  G+P RAG II TG+   +     G R EA + GIG
Sbjct: 213 RKMASLGEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIG 253


>Rv3536c [Q] COG3971 2-keto-4-pentenoate hydratase Mtu Mycobacterium
           tuberculosis H37Rv
          Length = 261

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 48/144 (33%), Positives = 67/144 (46%), Gaps = 14/144 (9%)

Query: 109 EAELRTVFDAILPAIEVVETRLGH---PPCTNPWAGMADLQSHGALVTGAPQALPDVLSL 165
           E ++    +A++PAIE+++TR+       C      +AD  S    V GA +  P  L +
Sbjct: 124 EDDVLAATEALVPAIELIDTRIKDWQIKICDT----IADNASAAGFVLGAARVPPADLDV 179

Query: 166 RQIEASLSIDGQQV----SHTTGGNPADLWPLLGWLALHCARRGQPWRAGQIITTGSCTG 221
           R I+A L+ +G+ V    S    GNPA     + WLA      G   R G I+  GSCT 
Sbjct: 180 RAIDAKLTRNGEVVAEGRSDAVLGNPA---TAVAWLAGKVESFGVRLRKGDIVLPGSCTF 236

Query: 222 LQMARGGRRVEAALHGIGAVWLDF 245
              AR G    A   G+G V L F
Sbjct: 237 AVEARAGDEFVADFTGLGLVRLSF 260


>MT3640 [Q] COG3971 2-keto-4-pentenoate hydratase MtC Mycobacterium
           tuberculosis CDC1551
          Length = 261

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 48/144 (33%), Positives = 67/144 (46%), Gaps = 14/144 (9%)

Query: 109 EAELRTVFDAILPAIEVVETRLGH---PPCTNPWAGMADLQSHGALVTGAPQALPDVLSL 165
           E ++    +A++PAIE+++TR+       C      +AD  S    V GA +  P  L +
Sbjct: 124 EDDVLAATEALVPAIELIDTRIKDWQIKICDT----IADNASAAGFVLGAARVPPADLDV 179

Query: 166 RQIEASLSIDGQQV----SHTTGGNPADLWPLLGWLALHCARRGQPWRAGQIITTGSCTG 221
           R I+A L+ +G+ V    S    GNPA     + WLA      G   R G I+  GSCT 
Sbjct: 180 RAIDAKLTRNGEVVAEGRSDAVLGNPA---TAVAWLAGKVESFGVRLRKGDIVLPGSCTF 236

Query: 222 LQMARGGRRVEAALHGIGAVWLDF 245
              AR G    A   G+G V L F
Sbjct: 237 AVEARAGDEFVADFTGLGLVRLSF 260