BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0054.p (457 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0075 [GEPR] COG0477 Permeases of the major facilitator superf... 623 e-178 PA0229 [GEPR] COG0477 Permeases of the major facilitator superfa... 598 e-170 STM2654 [GEPR] COG0477 Permeases of the major facilitator superf... 581 e-165 kgtP [GEPR] COG0477 Permeases of the major facilitator superfami... 561 e-159 ECs3454 [GEPR] COG0477 Permeases of the major facilitator superf... 560 e-159 >RSp0075 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 437 Score = 623 bits (1606), Expect = e-178, Method: Compositional matrix adjust. Identities = 304/430 (70%), Positives = 360/430 (83%), Gaps = 1/430 (0%) Query: 6 QASTPLSAA-EYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDPTSQLLNT 64 QAS + A + R+RIFAI+GASSGNLVEWFDFYVY+FC++YFAPAFFP G+ T+QL+NT Sbjct: 7 QASQAVMAPHDTRRRIFAIVGASSGNLVEWFDFYVYAFCSLYFAPAFFPSGNTTTQLMNT 66 Query: 65 AGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVMPTYATIGAWAPA 124 AGVFAAGFLMRPIGGWLFGRIAD+HGR+ +M+ISVLMMCGGSL +AV+P YA IGA AP Sbjct: 67 AGVFAAGFLMRPIGGWLFGRIADRHGRRNAMMISVLMMCGGSLVIAVLPIYAQIGALAPF 126 Query: 125 LLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFGMQQ 184 LLL+ARLFQGLSVGGEYGTSATYMSEVA GRRGFFASFQYVTLIGGQL A+LVL +QQ Sbjct: 127 LLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLCALLVLVILQQ 186 Query: 185 WLTKAELMAWGWRVPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKRAF 244 L+ AEL AWGWR+PFV+GA+ ALV++YLR SL ET S +R+ K AGT++G QHK AF Sbjct: 187 VLSTAELKAWGWRIPFVVGALSALVSLYLRRSLDETQSTASREAKHAGTIRGAWQHKGAF 246 Query: 245 LNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAISDK 304 L V+GFTAGGSL+FYTFTTYMQKYLVNTAGM+ K A+ VMT ALFVYM LQP+FGA+SD+ Sbjct: 247 LRVIGFTAGGSLIFYTFTTYMQKYLVNTAGMNTKTASNVMTAALFVYMALQPVFGALSDR 306 Query: 305 IGRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMF 364 IGRR SM+ F ++ T P++ L V++P A L AL I+SFYTSISGLIKAEMF Sbjct: 307 IGRRMSMILFGVGAVLFTVPLMRALGSVTNPYAAFGLVTAALAIISFYTSISGLIKAEMF 366 Query: 365 PPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGIESAFYWYVSALCLVALIISLRMPD 424 PPEVRA+GVGLSYA+ NA+FGGSAE+VAL KSAG ES FYWYV+ LC V+LI+S MPD Sbjct: 367 PPEVRAMGVGLSYAIANAVFGGSAEYVALWFKSAGRESTFYWYVTTLCAVSLIVSYTMPD 426 Query: 425 PQRDGHLKGD 434 P ++G+L+ + Sbjct: 427 PSKEGYLRHE 436 >PA0229 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 432 Score = 598 bits (1541), Expect = e-170, Method: Compositional matrix adjust. Identities = 306/423 (72%), Positives = 358/423 (84%) Query: 12 SAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDPTSQLLNTAGVFAAG 71 S E RKRIFAI+GASSGNLVEWFDFYVY+FCAIYFAPAFFP +PT QLLNTAGVFAAG Sbjct: 9 SNEERRKRIFAIVGASSGNLVEWFDFYVYAFCAIYFAPAFFPSDNPTVQLLNTAGVFAAG 68 Query: 72 FLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVMPTYATIGAWAPALLLLARL 131 FLMRPIGGW+FGRIADKHGRKT+MLISV+MMC GSLA+A MPTYA+IG APALLLLAR+ Sbjct: 69 FLMRPIGGWMFGRIADKHGRKTAMLISVVMMCAGSLAIACMPTYASIGTLAPALLLLARM 128 Query: 132 FQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFGMQQWLTKAEL 191 FQGLSVGGEYGTSATYMSEVA G+RGFFASFQYVTLIGGQLLAVLV+ +QQ L++ EL Sbjct: 129 FQGLSVGGEYGTSATYMSEVALKGQRGFFASFQYVTLIGGQLLAVLVVVILQQLLSEDEL 188 Query: 192 MAWGWRVPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKRAFLNVVGFT 251 AWGWR+PFV+GA+ A++A++LR SL ET+S ++K++GT L +HKRAF V+GFT Sbjct: 189 RAWGWRIPFVIGAITAVIALWLRRSLNETASKSTLERKESGTFAELFKHKRAFFTVLGFT 248 Query: 252 AGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAISDKIGRRNSM 311 AGGSL+FYTFTTYMQKYLVNTAGM K A+ VMT AL YM++QP+FG +SD+IGR+ SM Sbjct: 249 AGGSLIFYTFTTYMQKYLVNTAGMSAKTASAVMTFALLAYMLMQPLFGMLSDRIGRKTSM 308 Query: 312 LCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFPPEVRAL 371 L F G + T PIL LK VSSP +A L ILAL IVS YTSISGLIKAEMFPPEVRAL Sbjct: 309 LWFGTLGTLCTLPILLALKTVSSPYMAFFLIILALAIVSLYTSISGLIKAEMFPPEVRAL 368 Query: 372 GVGLSYAVGNAIFGGSAEFVALSLKSAGIESAFYWYVSALCLVALIISLRMPDPQRDGHL 431 GVG+SYAVGNAIFGGSAE+VAL LKS G+E+ FYWYVSA+CL+AL++ + +PD ++ +L Sbjct: 369 GVGVSYAVGNAIFGGSAEYVALGLKSVGMENVFYWYVSAMCLLALLVCVSLPDLRKVSYL 428 Query: 432 KGD 434 + Sbjct: 429 NDE 431 >STM2654 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 433 Score = 581 bits (1497), Expect = e-165, Method: Compositional matrix adjust. Identities = 297/432 (68%), Positives = 349/432 (80%), Gaps = 11/432 (2%) Query: 3 DTTQASTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDPTSQLL 62 D A P E R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QLL Sbjct: 9 DKNNAEAP----EMRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLL 64 Query: 63 NTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVMPTYATIGAWA 122 TAGVFAAGFLMRPIGGWLFGRIAD+ GRK SMLISV MMC GSL +A +P Y TIG WA Sbjct: 65 QTAGVFAAGFLMRPIGGWLFGRIADRRGRKASMLISVCMMCMGSLVIACLPGYDTIGTWA 124 Query: 123 PALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFGM 182 PALLL+ARLFQGLSVGGEYGTSATYMSEVA GR+GFFASFQYVTLIGGQLLA+LV+ + Sbjct: 125 PALLLIARLFQGLSVGGEYGTSATYMSEVALEGRKGFFASFQYVTLIGGQLLALLVVVIL 184 Query: 183 QQWLTKAELMAWGWRVPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKR 242 QQ L AEL AWGWR+PF LGAV A+VA++LR L ETS R K+AG+LKGL ++++ Sbjct: 185 QQVLDDAELRAWGWRIPFALGAVLAVVALWLRRQLDETSKHETRALKEAGSLKGLWRNRK 244 Query: 243 AFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAIS 302 AFL V+GFTA GSL FYTFTTYMQKYLVNTAGM VA+G+MT AL V+M++QP+FGA+S Sbjct: 245 AFLMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALCVFMLVQPLFGALS 304 Query: 303 DKIGRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAE 362 DKIGRR SMLCF + T PIL L++V+SP A AL I AL IVSFYTSISG++KAE Sbjct: 305 DKIGRRTSMLCFGALATLFTVPILSALQNVTSPYAAFALVICALLIVSFYTSISGILKAE 364 Query: 363 MFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGIESAFYWYVSALCLVALIISLRM 422 MFP +VRALGVGLSYAV NA+FGGSAE+VALSLKS G+ES+F+WYV+A+ ++A ++SL + Sbjct: 365 MFPAQVRALGVGLSYAVANALFGGSAEYVALSLKSVGMESSFFWYVTAMAVLAFLVSLML 424 Query: 423 PDPQRDGHLKGD 434 H KG Sbjct: 425 -------HRKGK 429 >kgtP [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 432 Score = 561 bits (1446), Expect = e-159, Method: Compositional matrix adjust. Identities = 293/433 (67%), Positives = 349/433 (80%), Gaps = 7/433 (1%) Query: 2 SDTTQASTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDPTSQL 61 T A + L++++ R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QL Sbjct: 3 ESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQL 62 Query: 62 LNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVMPTYATIGAW 121 L TAGVFAAGFLMRPIGGWLFGRIADKHGRK SML+SV MMC GSL +A +P Y TIG W Sbjct: 63 LQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTW 122 Query: 122 APALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFG 181 APALLLLARLFQGLSVGGEYGTSATYMSEVA GR+GF+ASFQYVTLIGGQLLA+LV+ Sbjct: 123 APALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVV 182 Query: 182 MQQWLTKAELMAWGWRVPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHK 241 +Q + A L WGWR+PF LGAV A+VA++LR L ETS R K+AG+LKGL +++ Sbjct: 183 LQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNR 242 Query: 242 RAFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAI 301 RAF+ V+GFTA GSL FYTFTTYMQKYLVNTAGM VA+G+MT ALFV+M++QP+ GA+ Sbjct: 243 RAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGAL 302 Query: 302 SDKIGRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKA 361 SDKIGRR SMLCF + T PIL L++VSSP A L + AL IVSFYTSISG++KA Sbjct: 303 SDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKA 362 Query: 362 EMFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGIESAFYWYVSALCLVALIISLR 421 EMFP +VRALGVGLSYAV NAIFGGSAE+VALSLKS G+E+AF+WYV+ + +VA ++SL Sbjct: 363 EMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLM 422 Query: 422 MPDPQRDGHLKGD 434 + H KG Sbjct: 423 L-------HRKGK 428 >ECs3454 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 432 Score = 560 bits (1442), Expect = e-159, Method: Compositional matrix adjust. Identities = 292/433 (67%), Positives = 349/433 (80%), Gaps = 7/433 (1%) Query: 2 SDTTQASTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDPTSQL 61 T A + L++++ R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QL Sbjct: 3 ESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQL 62 Query: 62 LNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVMPTYATIGAW 121 L TAGVFAAGFLMRPIGGWLFGRIADKHGRK SML+SV MMC GSL +A +P Y TIG W Sbjct: 63 LQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTW 122 Query: 122 APALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFG 181 APALLLLARLFQGLSVGGEYGTSATYMSEVA GR+GF+ASFQYVTLIGGQLLA+LV+ Sbjct: 123 APALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVV 182 Query: 182 MQQWLTKAELMAWGWRVPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHK 241 +Q + + L WGWR+PF LGAV A+VA++LR L ETS R K+AG+LKGL +++ Sbjct: 183 LQHTMEDSALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNR 242 Query: 242 RAFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAI 301 RAF+ V+GFTA GSL FYTFTTYMQKYLVNTAGM VA+G+MT ALFV+M++QP+ GA+ Sbjct: 243 RAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGAL 302 Query: 302 SDKIGRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKA 361 SDKIGRR SMLCF + T PIL L++VSSP A L + AL IVSFYTSISG++KA Sbjct: 303 SDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKA 362 Query: 362 EMFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGIESAFYWYVSALCLVALIISLR 421 EMFP +VRALGVGLSYAV NAIFGGSAE+VALSLKS G+E+AF+WYV+ + +VA ++SL Sbjct: 363 EMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLM 422 Query: 422 MPDPQRDGHLKGD 434 + H KG Sbjct: 423 L-------HRKGK 428