BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0237.p (223 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776448.1| cobalt/zinc/cadmium resistance two component... 449 e-124 ref|YP_553567.1| hypothetical protein Bxe_B1748a [Burkholderia x... 382 e-104 ref|YP_001888667.1| two component heavy metal response winged he... 379 e-103 ref|YP_003607270.1| transcriptional regulator [Burkholderia sp. ... 355 3e-96 ref|YP_004750844.1| DNA-binding heavy metal response regulator [... 355 4e-96 ref|ZP_03265149.1| two component heavy metal response transcript... 355 4e-96 ref|NP_891076.1| response regulatory protein [Bordetella bronchi... 345 3e-93 ref|YP_003331826.1| winged helix family two component transcript... 337 9e-91 ref|YP_003881005.1| DNA-binding heavy metal response regulator [... 334 4e-90 ref|YP_002989299.1| two component heavy metal response transcrip... 333 9e-90 >ref|YP_003776448.1| cobalt/zinc/cadmium resistance two component response regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ64540.1| cobalt/zinc/cadmium resistance two component response regulator protein [Herbaspirillum seropedicae SmR1] Length = 223 Score = 449 bits (1154), Expect = e-124, Method: Compositional matrix adjust. Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW Sbjct: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT Sbjct: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM Sbjct: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP Sbjct: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 >ref|YP_553567.1| hypothetical protein Bxe_B1748a [Burkholderia xenovorans LB400] ref|ZP_06842747.1| two component heavy metal response transcriptional regulator, winged helix family [Burkholderia sp. Ch1-1] gb|ABE34217.1| Hypothetical protein Bxe_B1748a [Burkholderia xenovorans LB400] gb|EFG69706.1| two component heavy metal response transcriptional regulator, winged helix family [Burkholderia sp. Ch1-1] Length = 223 Score = 382 bits (980), Expect = e-104, Method: Compositional matrix adjust. Identities = 183/221 (82%), Positives = 207/221 (93%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M+ILVIEDDPKTGDYL+KGLRESGYAVDLAR G DGLHMALE YDLVVLDVMLPG+DGW Sbjct: 1 MSILVIEDDPKTGDYLKKGLRESGYAVDLARTGTDGLHMALENAYDLVVLDVMLPGIDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 ++M ALR++RDLPV+FLTARDHV DRIRGL+LGADDYLVKPFSFTELVLRIRTLLRRGVT Sbjct: 61 EIMRALRARRDLPVIFLTARDHVSDRIRGLELGADDYLVKPFSFTELVLRIRTLLRRGVT 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 RE++V+EIADL+LD +R KVTR+GV I LTNKEFMLLHLL++RQGEALSR+ IAS++WDM Sbjct: 121 RESDVFEIADLKLDVLRRKVTREGVEIPLTNKEFMLLHLLVRRQGEALSRTQIASEVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSE 221 NFDSDTNVVDVAIKRLRAK+D PF+KKLIHTVRS+GY F + Sbjct: 181 NFDSDTNVVDVAIKRLRAKVDHPFEKKLIHTVRSIGYTFGD 221 >ref|YP_001888667.1| two component heavy metal response winged helix family transcriptional regulator [Burkholderia phytofirmans PsJN] gb|ACD19297.1| two component heavy metal response transcriptional regulator, winged helix family [Burkholderia phytofirmans PsJN] Length = 223 Score = 379 bits (974), Expect = e-103, Method: Compositional matrix adjust. Identities = 182/221 (82%), Positives = 205/221 (92%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M ILVIEDDPKTGDYL+KGLRESGYAVDLAR G DGLHMALE YDLVVLDVMLPG+DGW Sbjct: 1 MTILVIEDDPKTGDYLKKGLRESGYAVDLARTGTDGLHMALENAYDLVVLDVMLPGIDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 ++M ALR++RDLPV+FLTARDHV DRIRGL+LGADDYLVKPFSFTELVLRIRTLLRRGV Sbjct: 61 EIMRALRTRRDLPVIFLTARDHVSDRIRGLELGADDYLVKPFSFTELVLRIRTLLRRGVI 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 RE++V+EIADL+LD +R KVTR+GV I LTNKEFMLLHLL++RQGEALSR+ IAS++WDM Sbjct: 121 RESDVFEIADLKLDVLRRKVTREGVEIPLTNKEFMLLHLLVRRQGEALSRTQIASEVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSE 221 NFDSDTNVVDVAIKRLRAK+D PF+KKLIHTVRS+GY F + Sbjct: 181 NFDSDTNVVDVAIKRLRAKVDHPFEKKLIHTVRSIGYTFGD 221 >ref|YP_003607270.1| transcriptional regulator [Burkholderia sp. CCGE1002] gb|ADG17759.1| two component transcriptional regulator, winged helix family [Burkholderia sp. CCGE1002] Length = 223 Score = 355 bits (911), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 176/221 (79%), Positives = 206/221 (93%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M+ILVIEDDPKTGDYL+KGLRE+GYAVDLAR G DGLH+ALE DY+LVVLDVMLPG+DGW Sbjct: 1 MSILVIEDDPKTGDYLKKGLRENGYAVDLARTGTDGLHLALEHDYELVVLDVMLPGIDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 ++M ALR++RDL V+FLTARD V DRIRGL+LGADDYLVKPFSFTELVLRIRTLLRRGV Sbjct: 61 EIMRALRARRDLRVIFLTARDQVSDRIRGLELGADDYLVKPFSFTELVLRIRTLLRRGVI 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 RE++V+E+ADL+LD +R +VTR+GV+I LTNKEFMLLHLL++R+GEALSRS IAS++WDM Sbjct: 121 RESDVFEVADLKLDVLRRRVTREGVDIPLTNKEFMLLHLLVRREGEALSRSQIASEVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSE 221 NFDSDTNVVDVAIKRLRAK+D PF+KKLIHTVRS+GY F + Sbjct: 181 NFDSDTNVVDVAIKRLRAKVDHPFEKKLIHTVRSIGYTFGD 221 >ref|YP_004750844.1| DNA-binding heavy metal response regulator [Collimonas fungivorans Ter331] gb|AEK60021.1| DNA-binding heavy metal response regulator [Collimonas fungivorans Ter331] Length = 226 Score = 355 bits (910), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 181/226 (80%), Positives = 208/226 (92%), Gaps = 3/226 (1%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M+ILVIEDDPKTG YL+KGLRESGYAVDL RNG+DGLHMALE YDLVVLDVMLPG DGW Sbjct: 1 MSILVIEDDPKTGAYLKKGLRESGYAVDLVRNGSDGLHMALENSYDLVVLDVMLPGTDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 ++M ALR+KRDLPV+FLTARDHV+DRIRGL+LGADDYLVKPFSFTEL+LRIRTLLRRGV Sbjct: 61 KIMGALRAKRDLPVIFLTARDHVNDRIRGLELGADDYLVKPFSFTELLLRIRTLLRRGVV 120 Query: 121 REA---EVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQI 177 RE+ + +++ADLQLD +R KVTRQG +I LTNKEF+LLHLL+KR+GE LSR+VIAS++ Sbjct: 121 RESHELDFFQVADLQLDLLRRKVTRQGTDIVLTNKEFLLLHLLVKRKGEPLSRTVIASEV 180 Query: 178 WDMNFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 WDMNFDSDTNVVDVAIKRLRAKID PF+ KLIHTVRS+GYMF+E+P Sbjct: 181 WDMNFDSDTNVVDVAIKRLRAKIDNPFEHKLIHTVRSIGYMFAEDP 226 >ref|ZP_03265149.1| two component heavy metal response transcriptional regulator, winged helix family [Burkholderia sp. H160] gb|EEA03227.1| two component heavy metal response transcriptional regulator, winged helix family [Burkholderia sp. H160] Length = 223 Score = 355 bits (910), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 176/221 (79%), Positives = 206/221 (93%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M+ILVIEDDPKTGDYL+KGLRE+GYAVDLAR G DGLH+ALE DY+LVVLDVMLPG+DGW Sbjct: 1 MSILVIEDDPKTGDYLKKGLRENGYAVDLARTGTDGLHLALEHDYELVVLDVMLPGIDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 ++M ALR++RDL V+FLTARD V DRIRGL+LGADDYLVKPFSFTELVLRIRTLLRRGV Sbjct: 61 EIMRALRARRDLRVIFLTARDQVSDRIRGLELGADDYLVKPFSFTELVLRIRTLLRRGVI 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 RE++V+E+ADL+LD +R +VTR+GV+I LTNKEFMLLHLL++R+GEALSRS IAS++WDM Sbjct: 121 RESDVFEVADLKLDVLRRRVTREGVDIPLTNKEFMLLHLLVRREGEALSRSQIASEVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSE 221 NFDSDTNVVDVAIKRLRAK+D PF+KKLIHTVRS+GY F + Sbjct: 181 NFDSDTNVVDVAIKRLRAKVDHPFEKKLIHTVRSIGYTFGD 221 >ref|NP_891076.1| response regulatory protein [Bordetella bronchiseptica RB50] emb|CAE34905.1| response regulatory protein [Bordetella bronchiseptica RB50] Length = 223 Score = 345 bits (885), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 168/223 (75%), Positives = 192/223 (86%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 MAILVIEDD KTGDYL+KGL ESGY+VDLARNG DGLH EQ YD++VLDVMLPG DGW Sbjct: 1 MAILVIEDDLKTGDYLKKGLLESGYSVDLARNGIDGLHRLREQRYDVLVLDVMLPGKDGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 QV+ +R D+PV+FLTARDHV DRIRGL+LGADDYLVKPFSF ELVLRI+T+LRRG Sbjct: 61 QVIEEVRQDSDVPVIFLTARDHVADRIRGLRLGADDYLVKPFSFAELVLRIQTMLRRGAA 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 R AE ++ADL+LD VR KVTR G +I LTNKEFMLLHLLI+RQGEALSR++IAS++WDM Sbjct: 121 RAAETLQVADLRLDPVRRKVTRGGASIVLTNKEFMLLHLLIRRQGEALSRTIIASEVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 NFDSDTNVVDVAIKRLRAK+DAPF KLI TVR +GY +E+P Sbjct: 181 NFDSDTNVVDVAIKRLRAKVDAPFPLKLIQTVRGIGYALAEQP 223 >ref|YP_003331826.1| winged helix family two component transcriptional regulator [Dickeya dadantii Ech586] gb|ACZ75121.1| two component transcriptional regulator, winged helix family [Dickeya dadantii Ech586] Length = 223 Score = 337 bits (863), Expect = 9e-91, Method: Compositional matrix adjust. Identities = 165/223 (73%), Positives = 190/223 (85%), Gaps = 2/223 (0%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M ILV+EDD TGDYL+KGL E+GYAVDLARNG DGL ALE YD ++LDVMLPGL+GW Sbjct: 1 MRILVVEDDGSTGDYLKKGLTEAGYAVDLARNGTDGLFNALEHSYDAIILDVMLPGLNGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 Q++ LR K D+PVLFLTARD + DRI GL+LGADDYL+KPFSFTELVLRIRTLLRRGV Sbjct: 61 QIIEMLRKKSDVPVLFLTARDQLHDRIHGLELGADDYLIKPFSFTELVLRIRTLLRRGVV 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 REA+ Y +ADL+LD +R K TRQ V I LTNKEFMLLHLL++R+GE LSR++IASQ+WDM Sbjct: 121 READHYAVADLRLDVLRRKATRQEVVIPLTNKEFMLLHLLVRREGEVLSRTLIASQVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 NFDSDTNVVDVA+KRLRAKID PFD KLIHTVR +GY+ EP Sbjct: 181 NFDSDTNVVDVAVKRLRAKIDKPFDIKLIHTVRGIGYVC--EP 221 >ref|YP_003881005.1| DNA-binding heavy metal response regulator [Dickeya dadantii 3937] gb|ADM96448.1| DNA-binding heavy metal response regulator [Dickeya dadantii 3937] Length = 223 Score = 334 bits (857), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 164/223 (73%), Positives = 188/223 (84%), Gaps = 2/223 (0%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M ILVIEDD TGDYL+KGL E+GYAVDLARNG DGL ALE YD ++LDVMLPGL+GW Sbjct: 1 MRILVIEDDAGTGDYLKKGLTEAGYAVDLARNGTDGLFNALEHGYDAIILDVMLPGLNGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 Q++ LR K D+PVLFLTARD + DRI GL+LGADDYL+KPFSFTELVLR+RTLLRRG Sbjct: 61 QIIEMLRKKSDVPVLFLTARDQLHDRIHGLELGADDYLIKPFSFTELVLRMRTLLRRGAV 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 REA+ Y +ADLQLD +R K TRQ I LTNKEFMLLHLL++R+GE LSR++IASQ+WDM Sbjct: 121 READHYVVADLQLDVLRRKATRQDTAIPLTNKEFMLLHLLVRREGEVLSRTLIASQVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 NFDSDTNVVDVA+KRLRAKID PFD KLIHTVR +GY+ EP Sbjct: 181 NFDSDTNVVDVAVKRLRAKIDKPFDVKLIHTVRGIGYVC--EP 221 >ref|YP_002989299.1| two component heavy metal response transcriptional regulator, winged helix family [Dickeya dadantii Ech703] gb|ACS87477.1| two component heavy metal response transcriptional regulator, winged helix family [Dickeya dadantii Ech703] Length = 223 Score = 333 bits (855), Expect = 9e-90, Method: Compositional matrix adjust. Identities = 164/223 (73%), Positives = 190/223 (85%), Gaps = 2/223 (0%) Query: 1 MAILVIEDDPKTGDYLRKGLRESGYAVDLARNGADGLHMALEQDYDLVVLDVMLPGLDGW 60 M ILV+EDD TGDYL+KGL E+GYAVDLAR+G +GL ALE YD ++LDVMLPGL GW Sbjct: 1 MRILVVEDDVSTGDYLKKGLTEAGYAVDLARSGTEGLFNALEHGYDAIILDVMLPGLSGW 60 Query: 61 QVMSALRSKRDLPVLFLTARDHVDDRIRGLQLGADDYLVKPFSFTELVLRIRTLLRRGVT 120 Q++ LR K D+PVLFLTARD + DRIRGL+LGADDYL+KPFSFTELVLRIRTLLRRGV Sbjct: 61 QLIEMLRKKSDVPVLFLTARDQLHDRIRGLELGADDYLIKPFSFTELVLRIRTLLRRGVV 120 Query: 121 REAEVYEIADLQLDHVRHKVTRQGVNIALTNKEFMLLHLLIKRQGEALSRSVIASQIWDM 180 REA+ Y +ADL+LD +R K TRQ V I LTNKEFMLLHLL++R+GE LSR++IASQ+WDM Sbjct: 121 READHYAVADLRLDVLRRKATRQEVVIPLTNKEFMLLHLLVRREGEVLSRTLIASQVWDM 180 Query: 181 NFDSDTNVVDVAIKRLRAKIDAPFDKKLIHTVRSVGYMFSEEP 223 NFDSDTNVVDVA+KRLRAKID PFD KLIHTVR +GY+ EP Sbjct: 181 NFDSDTNVVDVAVKRLRAKIDKPFDIKLIHTVRGIGYVC--EP 221