BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0109.p (318 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776321.1| porphobilinogen deaminase [Herbaspirillum se... 625 e-177 ref|YP_001099316.1| porphobilinogen deaminase [Herminiimonas ars... 426 e-117 ref|YP_001352832.1| hydroxymethylbilane synthase [Janthinobacter... 416 e-114 ref|YP_004752065.1| porphobilinogen deaminase [Collimonas fungiv... 412 e-113 ref|YP_001858400.1| porphobilinogen deaminase [Burkholderia phym... 387 e-105 ref|YP_004416507.1| porphobilinogen deaminase [Pusillimonas sp. ... 384 e-105 gb|EGP44874.1| porphobilinogen deaminase [Achromobacter xylosoxi... 381 e-104 gb|EFV83446.1| HemC protein [Achromobacter xylosoxidans C54] 380 e-103 ref|YP_727364.1| porphobilinogen deaminase [Ralstonia eutropha H... 379 e-103 ref|YP_001900131.1| porphobilinogen deaminase [Ralstonia pickett... 375 e-102 >ref|YP_003776321.1| porphobilinogen deaminase [Herbaspirillum seropedicae SmR1] gb|ADJ64413.1| porphobilinogen deaminase protein [Herbaspirillum seropedicae SmR1] Length = 318 Score = 625 bits (1613), Expect = e-177, Method: Compositional matrix adjust. Identities = 316/318 (99%), Positives = 317/318 (99%) Query: 1 LKEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG 60 +KEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG Sbjct: 1 MKEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG 60 Query: 61 GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD 120 GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD Sbjct: 61 GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD 120 Query: 121 ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL 180 ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL Sbjct: 121 ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL 180 Query: 181 GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI 240 GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI Sbjct: 181 GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI 240 Query: 241 FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVR 300 FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLK R Sbjct: 241 FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKAR 300 Query: 301 GADDILAACKAQADAASA 318 GADDILAACKAQADAASA Sbjct: 301 GADDILAACKAQADAASA 318 >ref|YP_001099316.1| porphobilinogen deaminase [Herminiimonas arsenicoxydans] emb|CAL61189.1| Porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) [Herminiimonas arsenicoxydans] Length = 317 Score = 426 bits (1096), Expect = e-117, Method: Compositional matrix adjust. Identities = 223/318 (70%), Positives = 260/318 (81%), Gaps = 1/318 (0%) Query: 1 LKEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG 60 +K PP +VI SRESRLAMWQAE+VR++LA LYPQC+I ILG TTRGDQILDR LSKVG Sbjct: 1 MKFPPPKKLVIASRESRLAMWQAEHVREKLALLYPQCAIEILGMTTRGDQILDRTLSKVG 60 Query: 61 GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD 120 GKGLFVKELEVA+AE RADLAVH LKD+PM LPEGF LAA+LEREDPRDAFVSNDYA+LD Sbjct: 61 GKGLFVKELEVAIAERRADLAVHSLKDVPMSLPEGFALAAVLEREDPRDAFVSNDYASLD 120 Query: 121 ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL 180 +LPDGA+VGTSSLRRQA+IAARYP+LV++PLRGNLDTRL KLD+G+YAAIILA AGL RL Sbjct: 121 DLPDGAIVGTSSLRRQALIAARYPKLVIRPLRGNLDTRLGKLDKGEYAAIILAAAGLKRL 180 Query: 181 GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI 240 G+ RIR+ LDP QSLP+PGQG + IEI R D++ LAPL+ E A AER+VSR Sbjct: 181 GMPQRIRAVLDPEQSLPAPGQGAMGIEIHADRADLQEWLAPLNHEATAQAVTAERTVSRN 240 Query: 241 FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVR 300 FG SCQIPLAA+AT++ + LRAMIATPDG A A+ G A APEALG Q+AELL + Sbjct: 241 FGGSCQIPLAAFATIENGTMRLRAMIATPDGKRVARADLNGAAHAPEALGGQIAELLHQQ 300 Query: 301 GADDILAACKAQADAASA 318 A+ IL +CK + DA +A Sbjct: 301 EANAILESCKTE-DAGNA 317 >ref|YP_001352832.1| hydroxymethylbilane synthase [Janthinobacterium sp. Marseille] gb|ABR88938.1| hydroxymethylbilane synthase [Janthinobacterium sp. Marseille] Length = 317 Score = 416 bits (1069), Expect = e-114, Method: Compositional matrix adjust. Identities = 220/314 (70%), Positives = 254/314 (80%) Query: 1 LKEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG 60 +K PP +VI SRESRLAMWQAE+VR++LA LYPQCSI ILG TTRGDQILDR LSKVG Sbjct: 1 MKFPPPKKLVIASRESRLAMWQAEHVREKLAILYPQCSIEILGMTTRGDQILDRTLSKVG 60 Query: 61 GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD 120 GKGLFVKELEVA+AE RADLAVH LKD+ M LP+GFELAA+LEREDPRDAFVSN++ L+ Sbjct: 61 GKGLFVKELEVAIAEQRADLAVHSLKDVAMTLPDGFELAAVLEREDPRDAFVSNEFDTLE 120 Query: 121 ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL 180 LP GA+VGTSSLRRQA+IAARYPQLV++PLRGNLD RL KLD G+YAAIILA AGL RL Sbjct: 121 ALPAGAIVGTSSLRRQALIAARYPQLVIRPLRGNLDRRLGKLDNGEYAAIILAAAGLKRL 180 Query: 181 GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI 240 GL ARIRS+L P QSLP+PGQG +AIEI R D+K LAPL+ A+ AER+VSR Sbjct: 181 GLTARIRSYLPPEQSLPAPGQGAMAIEILSERADLKEWLAPLNHTETALAVTAERTVSRN 240 Query: 241 FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVR 300 FG SCQIPLAA+AT+DG + LRA+IATPDG A+A+ G A APEALG Q+A+ L+ + Sbjct: 241 FGGSCQIPLAAFATIDGVNMRLRAIIATPDGSKMASADLSGAANAPEALGRQIADALQQQ 300 Query: 301 GADDILAACKAQAD 314 A ILA CK AD Sbjct: 301 DAAAILALCKTDAD 314 >ref|YP_004752065.1| porphobilinogen deaminase [Collimonas fungivorans Ter331] gb|AEK61242.1| Porphobilinogen deaminase [Collimonas fungivorans Ter331] Length = 313 Score = 412 bits (1059), Expect = e-113, Method: Compositional matrix adjust. Identities = 215/306 (70%), Positives = 252/306 (82%) Query: 5 PPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGL 64 PPS +VI SRES LAMWQAE+VR+RL+ALYP C+I ILG TTRGDQILDR LSKVGGKGL Sbjct: 6 PPSKLVIASRESPLAMWQAEHVRERLSALYPDCNIEILGMTTRGDQILDRTLSKVGGKGL 65 Query: 65 FVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPD 124 FVKELEVAMAEGRADLAVH LKDMPM+LP GF L+A+LEREDPRDAFVSNDYA+L++LP Sbjct: 66 FVKELEVAMAEGRADLAVHSLKDMPMELPPGFVLSAVLEREDPRDAFVSNDYASLEQLPA 125 Query: 125 GAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKA 184 GA+VGTSSLRRQA+IAAR+P L +KPLRGNL TRLAKLDRG+YAAIILA AGL RLGL Sbjct: 126 GAIVGTSSLRRQALIAARFPLLQIKPLRGNLGTRLAKLDRGEYAAIILAAAGLKRLGLAD 185 Query: 185 RIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGAS 244 RI + ++P QSLP+PGQG +AIEI R D++ +LAPL+ P + AER++SR FG S Sbjct: 186 RITAPIEPEQSLPAPGQGAMAIEIRADRADLQEILAPLNHLPTELAVTAERTLSRAFGGS 245 Query: 245 CQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVRGADD 304 CQ+PLAA+AT+DG ++ LRAMIATPDGL A A+A G A APE LG +A L+ + A Sbjct: 246 CQVPLAAFATIDGDQMRLRAMIATPDGLRVAVADASGAADAPEVLGETIAAALEAQDAGA 305 Query: 305 ILAACK 310 ILA CK Sbjct: 306 ILALCK 311 >ref|YP_001858400.1| porphobilinogen deaminase [Burkholderia phymatum STM815] sp|B2JEN9.1|HEM3_BURP8 RecName: Full=Porphobilinogen deaminase; Short=PBG; AltName: Full=Hydroxymethylbilane synthase; Short=HMBS; AltName: Full=Pre-uroporphyrinogen synthase gb|ACC71354.1| porphobilinogen deaminase [Burkholderia phymatum STM815] Length = 327 Score = 387 bits (995), Expect = e-105, Method: Compositional matrix adjust. Identities = 214/322 (66%), Positives = 243/322 (75%), Gaps = 4/322 (1%) Query: 1 LKEFPPSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVG 60 L PP+ +VI SRESRLAMWQAE+VR L LYP C + ILG TTRGDQILDR LSKVG Sbjct: 6 LAPTPPATLVIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRTLSKVG 65 Query: 61 GKGLFVKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALD 120 GKGLFVKELE A+A+GRADLAVH LKD+PM+LPEGF L+ I+EREDPRDAFVSN Y +L Sbjct: 66 GKGLFVKELENALADGRADLAVHSLKDVPMELPEGFVLSTIMEREDPRDAFVSNQYDSLA 125 Query: 121 ELPDGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRL 180 LP G+VVGTSSLRR+AM+ ARYP+LVVKPLRGNLDTRL KLDRGDYAAIILA AGL RL Sbjct: 126 ALPAGSVVGTSSLRREAMLRARYPELVVKPLRGNLDTRLGKLDRGDYAAIILAAAGLKRL 185 Query: 181 GLKARIRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRI 240 GL RIRS LDPA SLP+ GQG L IEI GR+D+ LAPLH E A AER VSR Sbjct: 186 GLGERIRSLLDPADSLPAAGQGALGIEIRAGRDDLAAWLAPLHHEHTAAAVEAERMVSRT 245 Query: 241 FGASCQIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEA---LGAQVAELL 297 G SC++PLAAYAT LHLR ++ATPDG +A+A PAA +A LG +VA L Sbjct: 246 LGGSCEVPLAAYATWHDGALHLRGIVATPDGERVLSAQASAPAATTDAALELGREVASQL 305 Query: 298 KVRGADDIL-AACKAQADAASA 318 + +GA DI+ A A AASA Sbjct: 306 EAQGALDIVRALSTASGPAASA 327 >ref|YP_004416507.1| porphobilinogen deaminase [Pusillimonas sp. T7-7] gb|AEC19883.1| porphobilinogen deaminase [Pusillimonas sp. T7-7] Length = 315 Score = 384 bits (987), Expect = e-105, Method: Compositional matrix adjust. Identities = 192/301 (63%), Positives = 230/301 (76%) Query: 6 PSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGLF 65 P+ +VI +R SRLA+WQAE+VRDRL LYPQC +S+L TTRGDQILDR+LSKVGGKGLF Sbjct: 5 PAKLVIATRASRLALWQAEHVRDRLQTLYPQCQVSLLTMTTRGDQILDRSLSKVGGKGLF 64 Query: 66 VKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPDG 125 VKELE A+ +GRADLAVH LKD+P+D+ F L+ ILER+DPRDAFVSNDY++LD+LP G Sbjct: 65 VKELETALLDGRADLAVHSLKDVPVDMQSPFALSVILERDDPRDAFVSNDYSSLDDLPAG 124 Query: 126 AVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKAR 185 +VVGTSSLRR+A I RYPQL V+PLRGNLDTRL KLDRGDYAAIILA AGL RLGL+AR Sbjct: 125 SVVGTSSLRREAQIRQRYPQLQVQPLRGNLDTRLGKLDRGDYAAIILASAGLRRLGLEAR 184 Query: 186 IRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGASC 245 IRS L+P QSLP+ GQG L IEI E R D++ LAPL D + AER+VSR+ G SC Sbjct: 185 IRSHLNPEQSLPAAGQGALGIEILESRSDMQTWLAPLSDPDTTACALAERAVSRVLGGSC 244 Query: 246 QIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVRGADDI 305 Q+PLAA+A DG L +R ++A PDG A+ G + E LG ++A L GA I Sbjct: 245 QVPLAAFAQRDGNTLMVRGLVAEPDGSRIIRAQVSGDVSQAEELGVRIANELLEEGARII 304 Query: 306 L 306 L Sbjct: 305 L 305 >gb|EGP44874.1| porphobilinogen deaminase [Achromobacter xylosoxidans AXX-A] Length = 309 Score = 381 bits (979), Expect = e-104, Method: Compositional matrix adjust. Identities = 195/298 (65%), Positives = 228/298 (76%) Query: 9 IVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGLFVKE 68 +VI +R SRLA+WQAE+VRDRL LYP C++ +L TTRGDQILDR LSKVGGKGLFVKE Sbjct: 1 MVIATRASRLALWQAEHVRDRLRTLYPACAVELLTLTTRGDQILDRTLSKVGGKGLFVKE 60 Query: 69 LEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPDGAVV 128 LE A+ +GRADLAVHCLKDMP+DL FEL A+L+R DPRDAFVSN Y L +LP GAVV Sbjct: 61 LENALLDGRADLAVHCLKDMPVDLQAPFELCAVLDRADPRDAFVSNRYDTLADLPAGAVV 120 Query: 129 GTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRS 188 GTSSLRR++ I ARYPQLVVKPLRGNLDTRL KLDRG+Y AI+LA AGLNRLGL RIR Sbjct: 121 GTSSLRRESQIRARYPQLVVKPLRGNLDTRLGKLDRGEYDAIVLAAAGLNRLGLTDRIRC 180 Query: 189 FLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGASCQIP 248 LDPA LP+ GQG L IEI + R+D++ LAPL+D A +S AER+VSR G SCQ+P Sbjct: 181 LLDPADCLPAAGQGALTIEIRDDRDDMRAWLAPLNDATATSISLAERAVSRRLGGSCQVP 240 Query: 249 LAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVRGADDIL 306 LAAYA +DG +L LRA++A+PDG AE GP +A+G VA L GA IL Sbjct: 241 LAAYAEIDGGKLTLRALVASPDGTRTLRAERSGPVDQAQAIGEAVAAELFDAGAQAIL 298 >gb|EFV83446.1| HemC protein [Achromobacter xylosoxidans C54] Length = 314 Score = 380 bits (977), Expect = e-103, Method: Compositional matrix adjust. Identities = 198/311 (63%), Positives = 234/311 (75%), Gaps = 2/311 (0%) Query: 6 PSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGLF 65 P +VI +R SRLA+WQAE+VRDRL LYP C++ +L TTRGDQILDR LSKVGGKGLF Sbjct: 4 PQRLVIATRASRLALWQAEHVRDRLRTLYPACAVELLTLTTRGDQILDRTLSKVGGKGLF 63 Query: 66 VKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPDG 125 VKELE A+ +GRADLAVHCLKDMP+D+ FEL A+L+R DPRDAFVSN YA L +LP G Sbjct: 64 VKELETALLDGRADLAVHCLKDMPVDMQAPFELCAVLDRADPRDAFVSNRYATLADLPAG 123 Query: 126 AVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKAR 185 AVVGTSSLRR++ I ARYPQL+VKPLRGNLDTRL KLDRG+Y AI+LA AGLNRLGL R Sbjct: 124 AVVGTSSLRRESQIRARYPQLLVKPLRGNLDTRLGKLDRGEYDAIVLAAAGLNRLGLTDR 183 Query: 186 IRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGASC 245 I S LDPA+SLP+ GQG L IEI + R+D++ LAPL+D A +S AER+VSR G SC Sbjct: 184 ISSLLDPAESLPAAGQGALTIEIRDDRDDMRAWLAPLNDAGATSISLAERAVSRRLGGSC 243 Query: 246 QIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKVRGADDI 305 Q+PLAAYA + L LRA++A+PDG A GP A +A+G VA L GA I Sbjct: 244 QVPLAAYAEIADDTLTLRALVASPDGTRMLRAHGSGPVAQAQAIGEAVAAELFDAGAQAI 303 Query: 306 LAACKAQADAA 316 L + Q DAA Sbjct: 304 LD--ELQQDAA 312 >ref|YP_727364.1| porphobilinogen deaminase [Ralstonia eutropha H16] emb|CAJ93996.1| porphobilinogen deaminase [Ralstonia eutropha H16] Length = 337 Score = 379 bits (974), Expect = e-103, Method: Compositional matrix adjust. Identities = 199/316 (62%), Positives = 235/316 (74%), Gaps = 3/316 (0%) Query: 6 PSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGLF 65 P +VI SRESRLA+WQAE+VR L YP C +SILG TTRGDQILDR LSKVGGKGLF Sbjct: 18 PQKLVIASRESRLALWQAEHVRAALQQYYPACDVSILGMTTRGDQILDRTLSKVGGKGLF 77 Query: 66 VKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPDG 125 VKELE AM EGRADLAVH LKD+PM+LPEGF L A++EREDPRDA VS+ YA+LDE+P G Sbjct: 78 VKELEFAMDEGRADLAVHSLKDVPMELPEGFALTAVMEREDPRDALVSSAYASLDEMPAG 137 Query: 126 AVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKAR 185 VVGTSSLRR+A + +RYPQLV+KPLRGNLDTRL KLDRG+Y AIILA AGL RLGL R Sbjct: 138 TVVGTSSLRREAALRSRYPQLVIKPLRGNLDTRLGKLDRGEYGAIILAAAGLKRLGLGER 197 Query: 186 IRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGASC 245 IR+ + SLP+ GQG L IEI R ++ + LAPL+ +P A+ +AER+VSR+ G SC Sbjct: 198 IRALIPIDVSLPAAGQGALGIEILANRPELAQWLAPLNHQPTALAVSAERAVSRMLGGSC 257 Query: 246 QIPLAAYATLDGQRLHLRAMIATPDGLHAAAAEAEGPA---AAPEALGAQVAELLKVRGA 302 Q+PLAA+A +G +L L A +A PDG A A A GPA AA EALG A L +GA Sbjct: 258 QVPLAAHARWEGDQLKLDAFVALPDGTRAIRAAASGPAVDLAAAEALGQACARDLLAQGA 317 Query: 303 DDILAACKAQADAASA 318 + ILAA D A + Sbjct: 318 EAILAALADSGDPAGS 333 >ref|YP_001900131.1| porphobilinogen deaminase [Ralstonia pickettii 12J] ref|ZP_07676324.1| hydroxymethylbilane synthase [Ralstonia sp. 5_7_47FAA] gb|ACD27699.1| porphobilinogen deaminase [Ralstonia pickettii 12J] gb|EFP65228.1| hydroxymethylbilane synthase [Ralstonia sp. 5_7_47FAA] Length = 338 Score = 375 bits (962), Expect = e-102, Method: Compositional matrix adjust. Identities = 206/316 (65%), Positives = 241/316 (76%), Gaps = 4/316 (1%) Query: 6 PSNIVIVSRESRLAMWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGLF 65 P+ +VI SRESRLA+WQAE+VR L YP C +SILG TTRGDQILDR+L+KVGGKGLF Sbjct: 23 PTKLVIASRESRLALWQAEHVRAALQKYYPACDVSILGMTTRGDQILDRSLAKVGGKGLF 82 Query: 66 VKELEVAMAEGRADLAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPDG 125 VKELEVA+AEGRADLAVH LKD+PM+LPEGF L+AILEREDPRDAF+SNDYA L LP G Sbjct: 83 VKELEVALAEGRADLAVHSLKDVPMELPEGFALSAILEREDPRDAFISNDYADLASLPAG 142 Query: 126 AVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKAR 185 AVVGTSSLRR+A + AR+P LV++PLRGNLDTRL KLDRGDYAAIILA AGL RLGL R Sbjct: 143 AVVGTSSLRREASLRARFPHLVIQPLRGNLDTRLGKLDRGDYAAIILAAAGLKRLGLVDR 202 Query: 186 IRSFLDPAQSLPSPGQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGASC 245 IRS + P +SLP+ GQG L IEI R D++ LAPLHDEP A+ AER+VSRI G SC Sbjct: 203 IRSTIAPEESLPAAGQGALGIEIRADRADVRACLAPLHDEPTALAVTAERAVSRILGGSC 262 Query: 246 QIPLAAYATL-DGQRLHLRAMIATPDGLHAAAAEAEGPA---AAPEALGAQVAELLKVRG 301 Q+PLA++A DG L LRA +A+ DG AA+ E A +ALG +VA+ + G Sbjct: 263 QVPLASFAQWSDGGTLRLRAFVASQDGTRKLAADGEATPSTLAEADALGVRVAQQMLAGG 322 Query: 302 ADDILAACKAQADAAS 317 A DILA A A A+ Sbjct: 323 ARDILAMLGADAPPAT 338