BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0004.p (232 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773453.1| response regulator for cobalt/zinc/cadmium r... 455 e-126 ref|YP_004753177.1| putative response regulator for cobalt zinc ... 331 6e-89 ref|YP_296024.1| two component heavy metal response transcriptio... 329 2e-88 ref|YP_583899.1| DNA-binding response regulator in two-component... 321 4e-86 ref|YP_002257372.1| response regulator protein for cobalt zinc c... 318 6e-85 emb|CAQ36419.1| response regulator protein for cobalt zinc cadmi... 317 6e-85 gb|AEG70968.1| response regulator protein for cobalt zinc cadmiu... 317 7e-85 ref|ZP_00945433.1| CzcR [Ralstonia solanacearum UW551] >gi|83724... 316 2e-84 emb|CCA81744.1| response regulator in two-component regulatory s... 316 2e-84 ref|NP_522050.1| response regulator for cobalt zinc cadmium resi... 315 3e-84 >ref|YP_003773453.1| response regulator for cobalt/zinc/cadmium resistance transcription regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ61545.1| response regulator for cobalt/zinc/cadmium resistance transcription regulator protein [Herbaspirillum seropedicae SmR1] Length = 235 Score = 455 bits (1170), Expect = e-126, Method: Compositional matrix adjust. Identities = 232/235 (98%), Positives = 232/235 (98%), Gaps = 3/235 (1%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW Sbjct: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS Sbjct: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM Sbjct: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREG---REVREERP 232 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREG REVREERP Sbjct: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREGREVREVREERP 235 >ref|YP_004753177.1| putative response regulator for cobalt zinc cadmium resistance transcription regulator protein [Collimonas fungivorans Ter331] gb|AEK62354.1| putative response regulator for cobalt zinc cadmium resistance transcription regulator protein [Collimonas fungivorans Ter331] Length = 223 Score = 331 bits (848), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 159/222 (71%), Positives = 191/222 (86%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M ILLVEDEPK+G+YLR+GL+ESG+VVDWV+TG DGLH A T DY LI+LDVMLPGM+GW Sbjct: 1 MRILLVEDEPKAGEYLRKGLSESGYVVDWVRTGADGLHCATTEDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++ ELR+TH TPVLFLTARDEV+DR+KGLELGADDYLVKPFA+ EL+AR+RTLLRRGP Sbjct: 61 QVISELRKTHSTPVLFLTARDEVDDRIKGLELGADDYLVKPFAFAELVARIRTLLRRGPI 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE DL+ D+ +DV++R+VTR G+RIDLT KEF+LL+++ +R EVLSR IASQVWDM Sbjct: 121 READLLHIADMEIDVMKRRVTRNGERIDLTTKEFSLLYLMAKRQSEVLSRSLIASQVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVR 222 NFDSDTNVVDVA+RRLR K+DE + L+HTV GMGYV E R Sbjct: 181 NFDSDTNVVDVAIRRLRIKIDEPYAPPLIHTVRGMGYVLEDR 222 >ref|YP_296024.1| two component heavy metal response transcriptional regulator [Ralstonia eutropha JMP134] gb|AAZ61180.1| two component heavy metal response transcriptional regulator, winged helix family [Ralstonia eutropha JMP134] Length = 224 Score = 329 bits (844), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 165/222 (74%), Positives = 187/222 (84%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M IL+VEDEPK+G+YLR+GLTES FVVD TG DGLH A +Y LIILDVMLPGM+GW Sbjct: 1 MKILVVEDEPKTGEYLRKGLTESSFVVDVAVTGGDGLHQATEHEYDLIILDVMLPGMSGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 D+LR+LR DTPVLFLTARDEVEDRV+GLELG DDYL KPFA+ ELLARVRTLLRRGP Sbjct: 61 DVLRQLRERKDTPVLFLTARDEVEDRVRGLELGGDDYLAKPFAFVELLARVRTLLRRGPV 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE D IE D+ +DV+R +VTRAGQRIDLT +EFALLH L RR GEVLSR IASQVWDM Sbjct: 121 READRIEIGDLEIDVIRHRVTRAGQRIDLTPREFALLHFLARRHGEVLSRTHIASQVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVR 222 NFDSDTNVVDVA+RRLRAK+D+ F KL+H+V G+GYV E+R Sbjct: 181 NFDSDTNVVDVAIRRLRAKMDDHFAPKLIHSVRGIGYVLEIR 222 >ref|YP_583899.1| DNA-binding response regulator in two-component regulatory system with AgrS [Cupriavidus metallidurans CH34] gb|ABF08630.1| DNA-binding response regulator in two-component regulatory system with AgrS [Cupriavidus metallidurans CH34] Length = 224 Score = 321 bits (823), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 158/224 (70%), Positives = 187/224 (83%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M IL++EDEPK+G+YLR+GLTES FVVD TG DGLH+A DY L+ILDVMLPGMNGW Sbjct: 1 MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++L+ELR DTPVLFLTARDEVEDRVKGLELG DDYL KPFA+ ELLAR RTLLRRGP+ Sbjct: 61 EVLKELREHKDTPVLFLTARDEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPT 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE + IE +D+ +D+LR +V+R G RIDL+ +EFALLH L RR GEVLSR QIAS VWDM Sbjct: 121 REAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFLARRHGEVLSRTQIASHVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREG 224 NFDSDTNVVDVA+RRLRAK+D+ + KL+H+V G+GYV E R+ Sbjct: 181 NFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS 224 >ref|YP_002257372.1| response regulator protein for cobalt zinc cadmium resistance [Ralstonia solanacearum IPO1609] ref|YP_003747719.1| response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA [Ralstonia solanacearum CFBP2957] emb|CAQ59256.1| response regulator protein for cobalt zinc cadmium resistance [Ralstonia solanacearum IPO1609] emb|CBJ53303.1| response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA [Ralstonia solanacearum CFBP2957] Length = 224 Score = 318 bits (814), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 61 QVIRELRRRKATPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 220 >emb|CAQ36419.1| response regulator protein for cobalt zinc cadmium resistance [Ralstonia solanacearum MolK2] Length = 224 Score = 317 bits (813), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 61 QVIRELRRRKPTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 220 >gb|AEG70968.1| response regulator protein for cobalt zinc cadmium resistance [Ralstonia solanacearum Po82] Length = 246 Score = 317 bits (813), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 23 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAIEHDYDLIVLDVMLPGMDGW 82 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 83 QVIRELRRRKPTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 142 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 143 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 202 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 203 NFDSNTNVVDVAIRRLRAKVDDPFEPKLIHTLRGMGYVLD 242 >ref|ZP_00945433.1| CzcR [Ralstonia solanacearum UW551] gb|EAP72081.1| CzcR [Ralstonia solanacearum UW551] Length = 248 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 25 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 84 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 85 QVIRELRRRKATPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 144 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 145 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 204 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 205 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 244 >emb|CCA81744.1| response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA [blood disease bacterium R229] emb|CCA87692.1| response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA [Ralstonia syzygii R24] Length = 224 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 152/221 (68%), Positives = 188/221 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARV T+LRRGP Sbjct: 61 QVIRELRRHKTTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVHTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE +++E D+ +D ++R+VTRAG+RIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEILEIADLTIDTIKRRVTRAGRRIDLTAKEYALLHLLARRTGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEV 221 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLDT 221 >ref|NP_522050.1| response regulator for cobalt zinc cadmium resistance transcription regulator protein [Ralstonia solanacearum GMI1000] emb|CAD17640.1| probable response regulator for cobalt zinc cadmium resistance transcription regulator protein [Ralstonia solanacearum GMI1000] Length = 224 Score = 315 bits (807), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 152/220 (69%), Positives = 188/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARV T+LRRGP Sbjct: 61 QVIRELRRRKTTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVHTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE +++E D+ +D ++R+VTRAG+RIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEVLEIADLTIDTIKRRVTRAGRRIDLTAKEYALLHLLARRTGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 220