BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0002.p (778 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773452.1| hypothetical protein Hsero_0014 [Herbaspiril... 1480 0.0 ref|YP_001792318.1| PAS/PAC sensor-containing diguanylate cyclas... 485 e-134 ref|YP_003524202.1| diguanylate cyclase/phosphodiesterase with P... 382 e-103 emb|CBA26380.1| Uncharacterized signaling protein PA1727 [Curvib... 379 e-102 ref|YP_968413.1| PAS/PAC sensor-containing diguanylate cyclase/p... 377 e-102 ref|YP_004124695.1| diguanylate cyclase [Alicycliphilus denitrif... 374 e-101 ref|ZP_04763605.1| diguanylate cyclase/phosphodiesterase with PA... 374 e-101 ref|YP_003047860.1| PAS/PAC sensor-containing diguanylate cyclas... 373 e-101 ref|YP_003846945.1| diguanylate cyclase/phosphodiesterase with P... 372 e-100 ref|YP_003525419.1| diguanylate cyclase/phosphodiesterase with P... 372 e-100 >ref|YP_003773452.1| hypothetical protein Hsero_0014 [Herbaspirillum seropedicae SmR1] gb|ADJ61544.1| conserved hypothetical protein [Herbaspirillum seropedicae SmR1] Length = 726 Score = 1480 bits (3831), Expect = 0.0, Method: Compositional matrix adjust. Identities = 722/726 (99%), Positives = 724/726 (99%) Query: 53 MLRHGLVLPVWNLDQSDIMALLQGAMLDRQVVSIEVIDPEEKTLARRAEPQRSAGHLIHR 112 MLRHGLVLPVWNLDQSDIMALL+GAMLDRQVVSIEVIDPEEK LARRAEPQRSAGHLIHR Sbjct: 1 MLRHGLVLPVWNLDQSDIMALLKGAMLDRQVVSIEVIDPEEKALARRAEPQRSAGHLIHR 60 Query: 113 TAPLVMQQNQQDVSLGSLHIVVSDHQLQKKLAADKSFYALVLLAQAIVSLLIIGLLVYRR 172 TAPLVMQQNQQDVSLGSLHIVVSDHQLQKKLAADKSFYALVLLAQAIVSLLIIGLLVYRR Sbjct: 61 TAPLVMQQNQQDVSLGSLHIVVSDHQLQKKLAADKSFYALVLLAQAIVSLLIIGLLVYRR 120 Query: 173 ILGPIGKLTQATARIQRGSFEQGIDLPQQDEIGQLARHMEAMQASLKTLFDEQAAILGNI 232 ILGPIGKLTQATARIQRGSFEQGIDLPQQDEIGQLARHMEAMQASLKTLFDEQAAILGNI Sbjct: 121 ILGPIGKLTQATARIQRGSFEQGIDLPQQDEIGQLARHMEAMQASLKTLFDEQAAILGNI 180 Query: 233 PAGVLFVRKGKIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAA 292 PAGVLFVRKGKIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAA Sbjct: 181 PAGVLFVRKGKIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAA 240 Query: 293 GEIVLLRNASGASFPAELHTSLIDPARPGEQIWVVIDVSARLEAENRIDQLAFYDPVTQL 352 GEIVLLRNASGASFPAELHTSLIDPARPGEQIWVVIDVSARLEAENRIDQLAFYDPVTQL Sbjct: 241 GEIVLLRNASGASFPAELHTSLIDPARPGEQIWVVIDVSARLEAENRIDQLAFYDPVTQL 300 Query: 353 PNKKLFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSC 412 PNKKLFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVK DEMEQLLIECARRFSSC Sbjct: 301 PNKKLFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKADEMEQLLIECARRFSSC 360 Query: 413 ITAEQTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVN 472 ITAEQTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVN Sbjct: 361 ITAEQTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVN 420 Query: 473 LGINIVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAV 532 LGINIVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAV Sbjct: 421 LGINIVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAV 480 Query: 533 ARRQFIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLH 592 ARRQFIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLH Sbjct: 481 ARRQFIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLH 540 Query: 593 RICSDLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESM 652 RIC+DLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESM Sbjct: 541 RICTDLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESM 600 Query: 653 MVDHIEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAA 712 MVDHIEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAA Sbjct: 601 MVDHIEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAA 660 Query: 713 MASIIRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQFADLLN 772 MASIIRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQFADLLN Sbjct: 661 MASIIRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQFADLLN 720 Query: 773 TPGRFR 778 TPGRFR Sbjct: 721 TPGRFR 726 >ref|YP_001792318.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Leptothrix cholodnii SP-6] gb|ACB35553.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Leptothrix cholodnii SP-6] Length = 810 Score = 485 bits (1248), Expect = e-134, Method: Compositional matrix adjust. Identities = 278/755 (36%), Positives = 429/755 (56%), Gaps = 6/755 (0%) Query: 19 ALSLPVVVALTVLNGTRERQISADINKLVDEKVDMLRHGLVLPVWNLDQSDIMALLQGAM 78 L +P +V +T L R++QI ++ ++ +L LV+P WN D + + + AM Sbjct: 44 GLLVPALVGVTALTELRQKQIDQELVDKLENTAVLLGSSLVVPAWNYDIQGMTRITEAAM 103 Query: 79 LDRQVVSIEVIDPEEKTLARRAEPQRSAGHLIHRTAPLVMQQNQQDVS--LGSLHIVVSD 136 LD QVV I V DP L +P+R G + + + + D + GS+ I D Sbjct: 104 LDPQVVRITVRDPASAPLVSVEQPERRRGRSVVQRQDMRLSGQVIDKTEVAGSVEIEFDD 163 Query: 137 HQLQKKLAADKSFYALVLLAQAIVSLLIIGLLVYRRILGPIGKLTQATARIQRGSFEQGI 196 Q++ D+ YA +LL Q ++SL ++ ++ +L P+ L+ ++R+ G FE + Sbjct: 164 SLAQQQFKNDRQVYAFILLGQLLLSLGLMLAALHLWVLKPLTSLSAFSSRVAGGDFEHPL 223 Query: 197 DLPQQDEIGQLARHMEAMQASLKTLFDEQAAILGNIPAGVLFVRKGKIVFGNEAAQALLA 256 D + DEIG+LA M+ M+A LKT F EQ AIL NI GV+F R G I + A+ Sbjct: 224 DWSRPDEIGRLALQMDKMRADLKTSFAEQRAILTNIELGVIFERGGLIQLASRQAERSFG 283 Query: 257 RDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAAG---EIVLLRNASGASFPAELHTS 313 + G+ ++ E + + ARA+A + G E ++L G+ F A L Sbjct: 284 HPPGFMSGLPILAIYPEDARAGIASARAMAAIATGDGRHEEELMLHRRDGSQFWAHLRVR 343 Query: 314 LIDPARP-GEQIWVVIDVSARLEAENRIDQLAFYDPVTQLPNKKLFMDRLRRGLDRRRTS 372 +DPA+P IWV+ D+SAR E+ +++LAFYDP+TQLPN++L DRL + L S Sbjct: 344 QLDPAQPQAGCIWVIEDISARKAVEDEVNRLAFYDPLTQLPNRRLLRDRLAQALAASARS 403 Query: 373 GHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSCITAEQTVARMEGEKFALGTE 432 G GA+ +++ ++ +QLL +R + C+ TVAR+ G++F + + Sbjct: 404 GMHGALIFIDLDNFKSLNDTLGHARGDQLLKLVGQRLTHCVRESDTVARLGGDEFVVIVQ 463 Query: 433 IRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVNLGINIVRDEQYGASELVMQA 492 L EC E + ++ILDA P L + ++GI + D++ +L+ +A Sbjct: 464 DLGARLDECATQAEGVGEKILDALNQPYPLDGHVRHSTPSIGITLFADDRDSVDDLLKEA 523 Query: 493 ELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAVARRQFIVYYQPQVTYEGDVV 552 ++AM Q++ AGRN RFFD MQA+ QR+ LE ++R+++ F+++YQPQV G + Sbjct: 524 DMAMYQAKTAGRNTLRFFDADMQAMLVQRAALEEDMRESMRLSHFLLHYQPQVVGSGRIT 583 Query: 553 GAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLHRICSDLENWQREGLARDLVV 612 GAE L+RW HP+RG+V P FI LAED L+ +G VL C L +W + + L V Sbjct: 584 GAEVLLRWPHPLRGLVPPAEFIPLAEDTNLITALGHWVLETACKTLADWSAQDDMKHLSV 643 Query: 613 AINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESMMVDHIEDVITKMQALRSNEV 672 ++NVSA++F+ +FV I+ H +K+ELTES++V+ +ED++ KM AL+S V Sbjct: 644 SVNVSARQFRQPHFVAEVMSILERTGADPHLLKLELTESLLVEDVEDIVAKMSALKSRGV 703 Query: 673 SISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAAMASIIRSIIMLGQSLNLSII 732 SLDDFGTGYSSL++L R P+DQ+KIDQ+FVR++ D +I R ++ L SL L++I Sbjct: 704 GFSLDDFGTGYSSLAHLKRLPLDQLKIDQSFVRDILTDPNDLAIGRMVVALADSLGLTVI 763 Query: 733 AEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQF 767 AEGVE QR+ L GC YQGY +S+P+P E F Sbjct: 764 AEGVELAAQRELLAQIGCDAYQGYLFSRPLPREPF 798 >ref|YP_003524202.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Sideroxydans lithotrophicus ES-1] gb|ADE11815.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Sideroxydans lithotrophicus ES-1] Length = 694 Score = 382 bits (980), Expect = e-103, Method: Compositional matrix adjust. Identities = 209/535 (39%), Positives = 310/535 (57%), Gaps = 5/535 (0%) Query: 241 KGKIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVA--RAVARSSGAAGEIVLL 298 KG+I+ N+A ++G L A Y A ++ RS GE V Sbjct: 155 KGRILRVNKAFTESTGYSVDEIIGQTPRLLKSNRHDSAFYAAMWESITRSGSWQGE-VWD 213 Query: 299 RNASGASFPAELHTSLIDPARPGEQIWVVI--DVSARLEAENRIDQLAFYDPVTQLPNKK 356 R +G +P L + I A +V D+S R AE I LAFYDP+TQLPN++ Sbjct: 214 RRKNGEIYPKWLSITAIKDADGNVTNYVGTHTDISERKTAEEEIRNLAFYDPLTQLPNRR 273 Query: 357 LFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSCITAE 416 L DRL+ + + GA+ +++ ++ + LL + A+R +SC+ + Sbjct: 274 LLQDRLQHAMSSTERNRKGGALLFLDLDNFKSINDTLGHTAGDNLLQQVAQRLTSCVRED 333 Query: 417 QTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVNLGIN 476 TV+R+ G++F + E SNE+ E E + ++I+ P L + ++GI Sbjct: 334 DTVSRIGGDEFVVMLEYLSNEVLEAAAQAETIGEKIIAELNQPYYLGGQELYNTPSIGIT 393 Query: 477 IVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAVARRQ 536 + D + G +L QA++AM Q++ +GRN RFFDP MQ N R LE ELR+A+ +Q Sbjct: 394 LFDDNRNGYEDLFKQADIAMYQAKKSGRNTLRFFDPKMQGSINTRVALERELRKALDSQQ 453 Query: 537 FIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLHRICS 596 F ++YQ QV G G EAL+RW HP RG+V P FISLAE+ GL+ IG VL C Sbjct: 454 FRLHYQIQVDSSGLPFGVEALIRWLHPERGLVPPFEFISLAEETGLICPIGEWVLETACK 513 Query: 597 DLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESMMVDH 656 L+ W+R L +DL++++NVSA++F +FV + E + H V +K+ELTESM++D Sbjct: 514 QLKLWERHELTQDLIMSVNVSAKQFYQSDFVVKVLEAIHRHDVNPSLLKLELTESMLLDK 573 Query: 657 IEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAAMASI 716 IED I+ M AL++ V SLDDFGTGYSSL YL R P++Q+KID++FVR++ D++ +I Sbjct: 574 IEDTISTMNALKAVGVRFSLDDFGTGYSSLQYLKRLPLNQLKIDRSFVRDIAVDSSDEAI 633 Query: 717 IRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQFADLL 771 + +II + SLNL +IAEGVET++Q+ L +GC+ YQGY + KP+P EQ +L Sbjct: 634 VSTIIAMAHSLNLDVIAEGVETDEQKQILLNKGCIHYQGYLFGKPVPIEQLEVML 688 >emb|CBA26380.1| Uncharacterized signaling protein PA1727 [Curvibacter putative symbiont of Hydra magnipapillata] Length = 649 Score = 379 bits (972), Expect = e-102, Method: Compositional matrix adjust. Identities = 190/471 (40%), Positives = 292/471 (61%), Gaps = 2/471 (0%) Query: 299 RNASGASFPAELHTSLIDPARPGEQIWV--VIDVSARLEAENRIDQLAFYDPVTQLPNKK 356 R +G P LH + ++ +V V D++ R AE++I QLAFYDP+T LPN++ Sbjct: 165 RRKNGEIHPQWLHITAVNDETGAVSHFVATVTDITQRKAAEDQIRQLAFYDPLTGLPNRR 224 Query: 357 LFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSCITAE 416 + +DRLR L S H GA+ +++ ++ D+ + LL + A+R + E Sbjct: 225 MLIDRLRHALASSARSAHCGALLFIDLDHFKNLNDTLGHDKGDLLLQQVAQRLLDTVREE 284 Query: 417 QTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVNLGIN 476 TVAR+ G+++ + E A+ ++I+ P L+ F + ++G+ Sbjct: 285 DTVARLGGDEYVVMLEGLDEFHDIAASQATAVGEKIIAKLNWPYQLAGHEFHSTPSMGLT 344 Query: 477 IVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAVARRQ 536 + + +L+ QA+LAM Q++ AGRN RF+DP MQA +R++LEA++RQ + Q Sbjct: 345 LFNGHEVEVEDLLKQADLAMYQAKGAGRNGLRFYDPQMQAAVTKRAELEADIRQGILFGQ 404 Query: 537 FIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLHRICS 596 F++++QPQV G V+GAEAL+RW HP RG+VSP FI +AED G + +G +L C+ Sbjct: 405 FVLFFQPQVDKSGCVMGAEALLRWNHPTRGMVSPAEFIPVAEDSGQILTLGSWILEAACA 464 Query: 597 DLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESMMVDH 656 L W + R L +A+NVS+++F+ +F +++ H +K+ELTES++ D+ Sbjct: 465 QLVAWAADPETRALTLAVNVSSRQFRQQDFAQHILDMLDYTGANPHCLKLELTESLLADN 524 Query: 657 IEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAAMASI 716 ++DVI KM ALR+ V SLDDFGTGYSSLSYL R P+DQ+KIDQ+FVR++ D A+I Sbjct: 525 LDDVIVKMSALRARGVGFSLDDFGTGYSSLSYLKRLPLDQLKIDQSFVRDVLTDPNDAAI 584 Query: 717 IRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQF 767 +++I+ LG++L L +IAEGVET +QRDFL A GC YQGY YS+P+P ++F Sbjct: 585 VQTILALGKTLGLKVIAEGVETGEQRDFLVANGCNSYQGYLYSRPVPADEF 635 >ref|YP_968413.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Acidovorax citrulli AAC00-1] gb|ABM30639.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Acidovorax citrulli AAC00-1] Length = 1499 Score = 377 bits (967), Expect = e-102, Method: Compositional matrix adjust. Identities = 209/532 (39%), Positives = 300/532 (56%), Gaps = 4/532 (0%) Query: 243 KIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAAGEIVLLRNAS 302 +I F NE A+ L G + +L + Q+ + RA AGEIV Sbjct: 962 RITFWNEGAERLYGWTREEATGQSIAELLYQDTQEFLRATRATQEQGEWAGEIVQFHR-D 1020 Query: 303 GASFPAELHTSLI--DPARPGEQIWVVIDVSARLEAENRIDQLAFYDPVTQLPNKKLFMD 360 G E +LI + +P + + D+ R E I +LAFYD +T LPN+ L MD Sbjct: 1021 GRRLDVEGRWTLIQGEQGQPDAILAIDTDIGQRKATEREIQRLAFYDSLTGLPNRMLLMD 1080 Query: 361 RLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSCITAEQTVA 420 R+R L + GA+ +++ ++ D+ + LL + A R ++C+ + TVA Sbjct: 1081 RMRHALATAQRRRQGGALLFIDLDNFKTLNDTLGHDQGDVLLQQVAARLNTCVRSVDTVA 1140 Query: 421 RMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVNLGINIVRD 480 R+ G++F + E S E + ++IL P L + + ++G+ D Sbjct: 1141 RLGGDEFVVMIEGLSTHPGELAMSARTVGEKILAVLATPYVLQGYHYRSTPSIGVAPFGD 1200 Query: 481 EQYGA-SELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAVARRQFIV 539 + EL+ QA+LAM Q++ AGRN RFFDP MQA+ R++LE +LR A+AR QF++ Sbjct: 1201 GRTSTVGELLKQADLAMYQAKTAGRNTLRFFDPGMQAVVTARAELENDLRTALAREQFML 1260 Query: 540 YYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLHRICSDLE 599 +YQPQ+ G V G EALVRW HP RG+VSP FI LAE+ GL+ +GR VLH C+ L Sbjct: 1261 HYQPQIDRRGSVTGVEALVRWPHPQRGMVSPGEFIPLAEETGLVLPLGRWVLHTACAQLA 1320 Query: 600 NWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESMMVDHIED 659 WQ L +A+NVS+++F + FV + P+ +K+ELTES+ V+ +E Sbjct: 1321 RWQHVPGRGHLSMAVNVSSRQFHHEAFVEDVVRAITATGAPASRLKLELTESLFVEDMET 1380 Query: 660 VITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAAMASIIRS 719 I M ALRS+ V SLDDFGTGYSSLSYL R P+DQ+KIDQ+FVR++ D A+I+ + Sbjct: 1381 TIATMAALRSHGVGFSLDDFGTGYSSLSYLKRMPLDQLKIDQSFVRDLLADPNDAAIVDT 1440 Query: 720 IIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQFADLL 771 II L +SL L +IAEGVET +QR L GC YQGY++S+P+P D L Sbjct: 1441 IIALSRSLGLDVIAEGVETAEQRTRLEQAGCRAYQGYFFSRPLPETALEDFL 1492 >ref|YP_004124695.1| diguanylate cyclase [Alicycliphilus denitrificans BC] ref|YP_004385981.1| PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase [Alicycliphilus denitrificans K601] gb|ADU97807.1| diguanylate cyclase [Alicycliphilus denitrificans BC] gb|AEB82465.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) [Alicycliphilus denitrificans K601] Length = 1206 Score = 374 bits (960), Expect = e-101, Method: Compositional matrix adjust. Identities = 198/534 (37%), Positives = 322/534 (60%), Gaps = 5/534 (0%) Query: 243 KIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAAGEIVLLRNAS 302 +I F NE A+ + +G + L + ++ V + +GEIV R+ + Sbjct: 666 RITFWNEGAERMYGWSREEALGRSMASLLHHDPEDFLHATAQVLQHGDWSGEIVQ-RSRN 724 Query: 303 GASFPAELHTSLI--DPARPGEQIWVVIDVSARLEAENRIDQLAFYDPVTQLPNKKLFMD 360 G S E +L+ D P + + D+ R E I +LAF+DP+T LPN+ FM Sbjct: 725 GRSIEVEGRWTLVRNDQGEPESILAIDSDIGPRKSHEREIQRLAFFDPLTGLPNRAQFMQ 784 Query: 361 RLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSCITAEQTVA 420 R+ L R GA+ +++ ++ D+ ++LL A+R S+C+ + TVA Sbjct: 785 RMGHALATARRQHQGGALLFIDLDNFKTLNDTLGHDQGDRLLQLVAQRLSTCVRSVDTVA 844 Query: 421 RMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVNLGINIVRD 480 R+ G++F + E + A + + ++IL+ P +L+ ++ + ++GI + D Sbjct: 845 RLGGDEFVVLLEQLTAHAATLAEHANKVGEKILNVLCVPYALAGHQYRSTPSIGIALFDD 904 Query: 481 EQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAVARRQFIVY 540 +L+ QA+LAM Q++ AGR+ RFFDP MQ ++R+ LEA+LR A+++++F ++ Sbjct: 905 TPTSMGDLLKQADLAMYQAKNAGRSTLRFFDPGMQRAVDERATLEADLRNALSQQEFTLH 964 Query: 541 YQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLHRICSDLEN 600 YQPQV G ++G EAL+RW HP RG+VSP FI +AE+ GL+ +GR VLH+ C+ L Sbjct: 965 YQPQVDSRGGILGVEALLRWTHPQRGMVSPAQFIPVAEETGLILPLGRWVLHKACTLLAA 1024 Query: 601 WQR-EGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESMMVDHIED 659 WQ+ GLA L +A+NVS+++F+ FV ++ PS +K+ELTES++V+ + Sbjct: 1025 WQKFPGLAH-LTMAVNVSSRQFRDPGFVGDVARVLAVTGAPSAQLKLELTESLLVEDMVS 1083 Query: 660 VITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAAMASIIRS 719 I M+ALR++ V SLDDFGTGYSSL+YL R P++Q+KID++FVR++ D A+I+R+ Sbjct: 1084 TIATMEALRAHGVGFSLDDFGTGYSSLAYLKRMPLEQLKIDRSFVRDLLADENNAAIVRT 1143 Query: 720 IIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIPGEQFADLLNT 773 I+ L SL LS+IAEGVET++QR++L GC +YQGY++++P+ ++ LL + Sbjct: 1144 IVALAASLGLSVIAEGVETDEQRNWLTRAGCTVYQGYFFNRPLSSDRLDGLLRS 1197 >ref|ZP_04763605.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) [Acidovorax delafieldii 2AN] gb|EER59589.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) [Acidovorax delafieldii 2AN] Length = 1624 Score = 374 bits (959), Expect = e-101, Method: Compositional matrix adjust. Identities = 203/522 (38%), Positives = 306/522 (58%), Gaps = 3/522 (0%) Query: 243 KIVFGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVARSSGAAGEIVLLRNAS 302 +I++ N++A+ L + +G + E L + Q + GEIV R+ Sbjct: 1090 RIIYWNKSAERLYGWSQLQALGQSIETLLYDDPAQFRRATQTTVEQGEWTGEIVQ-RHRD 1148 Query: 303 GASFPAELHTSLI--DPARPGEQIWVVIDVSARLEAENRIDQLAFYDPVTQLPNKKLFMD 360 G+ E +L+ D R + + D+ R E I +LAFYDP+T LPN+ L MD Sbjct: 1149 GSPIDVEGRWTLVKDDAGRAHSVLAINTDIRERKATEREIQRLAFYDPLTGLPNRMLLMD 1208 Query: 361 RLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIECARRFSSCITAEQTVA 420 R+ + L + GA+ +++ ++ D+ + LL + A R ++C+ + TVA Sbjct: 1209 RIGQALATAQRRHQGGALLFIDLDNFKTLNDTLGHDQGDLLLQQVAHRLNNCVRSVDTVA 1268 Query: 421 RMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSAARFPCSVNLGINIVRD 480 R+ G++F + E S + E A+ +++L P +L ++ + ++GI Sbjct: 1269 RLGGDEFVVMLEELSPQPDELALDARAVGEKVLAMLAVPYALKGYQYRSTPSIGIAPFDG 1328 Query: 481 EQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQLEAELRQAVARRQFIVY 540 +Q EL+ QA+LAM Q++ AGRN RFFDPAMQ + R+ LE + R A+A +F+++ Sbjct: 1329 DQATVGELLKQADLAMYQAKTAGRNTLRFFDPAMQDVVTARAALEEDFRTALANDEFLLH 1388 Query: 541 YQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMDEIGRQVLHRICSDLEN 600 YQPQV G VG EALVRW HP RG+VSP FI LAE+ GL+ +GR VLH C+ L Sbjct: 1389 YQPQVNLAGQCVGVEALVRWAHPQRGLVSPAEFIPLAEETGLILSLGRWVLHTACTQLAL 1448 Query: 601 WQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSVKVELTESMMVDHIEDV 660 WQ + + +L +A+NVS+++F+ +FV ++ PS +K+ELTES++V+ +E Sbjct: 1449 WQDDPMLSELTMAVNVSSRQFRHASFVDDVARVLAITGAPSGLLKLELTESLLVEDMETT 1508 Query: 661 ITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFVREMQNDAAMASIIRSI 720 I M AL + V SLDDFGTGYSSLSYL R P+DQ+KIDQ+FVR++ D A+I+ +I Sbjct: 1509 IATMAALGAYGVGFSLDDFGTGYSSLSYLKRMPLDQLKIDQSFVRDLLTDPNDAAIVDTI 1568 Query: 721 IMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPI 762 I L +SL L +IAEGVET +QRD L GC LYQGY +S+P+ Sbjct: 1569 IGLSRSLGLEVIAEGVETPEQRDLLARAGCHLYQGYLFSRPL 1610 >ref|YP_003047860.1| PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase [Methylotenera mobilis JLW8] gb|ACT47333.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Methylotenera mobilis JLW8] Length = 976 Score = 373 bits (957), Expect = e-101, Method: Compositional matrix adjust. Identities = 190/494 (38%), Positives = 295/494 (59%), Gaps = 6/494 (1%) Query: 287 RSSGAAGEIVLLRNASGASFPAELHTSLIDPA--RPGEQIWVVIDVSARLEAENRIDQLA 344 R +G+ ++ R +G +P L + + A + + + D+S A RI+ LA Sbjct: 477 RETGSWSGEIINRRKNGEIYPEHLTITAVKDADGQTTNYVGMFTDISVAKAASERIENLA 536 Query: 345 FYDPVTQLPNKKLFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLLIE 404 F+DP+T LPN++LF DRL + L SG+ GA+ +++ ++ D + LL + Sbjct: 537 FFDPLTNLPNRRLFSDRLTQALVNSTRSGNYGALVFLDLDHFKSLNDTLGHDYGDMLLKQ 596 Query: 405 CARRFSSCITAEQTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSLSA 464 A R S+C+ +VAR+ G++F L E S E EA+ +IL + P L + Sbjct: 597 VALRLSNCVREGDSVARLGGDEFVLLVENLSANDVEAAHQIEAIGDKILMSLNQPYQLQS 656 Query: 465 ARFPCSVNLGINIVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRSQL 524 + + ++GI++ Q + +L+ A++AM Q++ AGRN RFFDP MQ N R L Sbjct: 657 HEYLSTPSIGISLFNGHQESSEDLLKHADIAMYQAKKAGRNTLRFFDPLMQETINMRVDL 716 Query: 525 EAELRQAVARRQFIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGLMD 584 E EL++A+ ++QF +YYQ Q+ G GAEAL+RW+HP RGI+SP FI +AE+ GL+ Sbjct: 717 ERELKKAIEQKQFELYYQVQMNSAGQPSGAEALIRWRHPERGIISPIQFIPVAEETGLIT 776 Query: 585 EIGRQVLHRICSDLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSHSV 644 +IG VL++ C L+ WQ + ++D +AINVSA++F +F + + +R H+ + + Sbjct: 777 QIGEWVLNQACLQLQAWQLDQASKDFSLAINVSAKQFLQPDFANQVKNSIRSFHIDNTKL 836 Query: 645 KVELTESMMVDHIEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQTFV 704 K+ELTESM++D+IE VI M L + SLDDFGTGYSSL YL P+ Q+KIDQ+FV Sbjct: 837 KLELTESMLIDNIEYVIHTMNTLGEIGIQFSLDDFGTGYSSLQYLKMLPLSQLKIDQSFV 896 Query: 705 REMQNDAAMASIIRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPIP- 763 R++ D + +I+ +II + SL L++IAEGVET++Q L+A GC YQGY++S+P+ Sbjct: 897 RDLATDNSNKTIVLTIITMAHSLGLNVIAEGVETDEQLQLLNAHGCGNYQGYYFSEPLSI 956 Query: 764 ---GEQFADLLNTP 774 Q+ N P Sbjct: 957 NEFNHQYMQFKNNP 970 >ref|YP_003846945.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Gallionella capsiferriformans ES-2] gb|ADL55181.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Gallionella capsiferriformans ES-2] Length = 1013 Score = 372 bits (955), Expect = e-100, Method: Compositional matrix adjust. Identities = 185/443 (41%), Positives = 280/443 (63%) Query: 329 DVSARLEAENRIDQLAFYDPVTQLPNKKLFMDRLRRGLDRRRTSGHAGAVFVMEIHRADL 388 D++A AE+ I +LAFYDP+T LPN++L DRL L + + GA+ +++ Sbjct: 569 DITANKAAESEIKKLAFYDPLTLLPNRRLLTDRLNHALASSARNRNIGALLFIDLDNFKT 628 Query: 389 SYGSVKVDEMEQLLIECARRFSSCITAEQTVARMEGEKFALGTEIRSNELAECIRYCEAL 448 ++ D + LL + A R SCI + T+AR+ G++F + E S + E + Sbjct: 629 LNDTLGHDMGDALLKQVALRLKSCIREDDTLARLGGDEFVVILENLSELAMDAATKAELI 688 Query: 449 AQRILDAFTDPQSLSAARFPCSVNLGINIVRDEQYGASELVMQAELAMVQSRAAGRNVFR 508 ++IL A L++ + + ++G+ + EL+ QA++AM QS+ +GRN R Sbjct: 689 GEKILAALNQVYPLASQEYHGAASIGVTLFAGHALSIDELMKQADIAMYQSKKSGRNTLR 748 Query: 509 FFDPAMQALANQRSQLEAELRQAVARRQFIVYYQPQVTYEGDVVGAEALVRWQHPIRGIV 568 FFD Q + N+R++LE ELR+AV ++Q ++YQ Q+ G + AEAL+RW HP+RG++ Sbjct: 749 FFDLDTQKIINERAELEIELRKAVDKKQLHLHYQIQLNSVGTPLSAEALIRWVHPVRGLI 808 Query: 569 SPTTFISLAEDMGLMDEIGRQVLHRICSDLENWQREGLARDLVVAINVSAQEFKVDNFVY 628 SP FI LAED GL+ IG+ VL C+ L +WQ E +DL +A+NVSA++F NFV Sbjct: 809 SPAHFIPLAEDTGLILPIGQWVLDTACAQLHSWQDERFTQDLTLAVNVSAKQFHQKNFVA 868 Query: 629 RFREIMREHHVPSHSVKVELTESMMVDHIEDVITKMQALRSNEVSISLDDFGTGYSSLSY 688 +E ++ H + +K+ELTESM+V++IED+I M ALR + SLDDFGTGYSSL Y Sbjct: 869 LVKETVQRHAINPKLLKLELTESMLVENIEDIIVTMNALREMGIQFSLDDFGTGYSSLQY 928 Query: 689 LGRFPIDQIKIDQTFVREMQNDAAMASIIRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQ 748 L R P++Q+KIDQ+FVRE+ + ++ +I+R+I+ + +SLNL++IAEGVETE+Q L Sbjct: 929 LKRLPLNQLKIDQSFVRELSSSSSDRAIVRTIVAMAESLNLNVIAEGVETEEQHTLLQDI 988 Query: 749 GCLLYQGYWYSKPIPGEQFADLL 771 GC YQGY + KP+P EQ +L Sbjct: 989 GCNYYQGYLFGKPMPIEQLDAIL 1011 >ref|YP_003525419.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Sideroxydans lithotrophicus ES-1] gb|ADE13032.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [Sideroxydans lithotrophicus ES-1] Length = 814 Score = 372 bits (954), Expect = e-100, Method: Compositional matrix adjust. Identities = 205/554 (37%), Positives = 318/554 (57%), Gaps = 11/554 (1%) Query: 228 ILGNIPAGVLFVRKGKIV-FGNEAAQALLARDDRRLVGVAAEDLFVESVQQAVYVARAVA 286 +L ++P G+ ++ + N+ LL ++G+ + + +++ ++ A Sbjct: 265 LLSHLPVGIFHYNTDLVITYCNDRLAELLHNSVEHVIGLDMKLVKDQAILPSLRKALEGE 324 Query: 287 RSSGAAGEIVLLRNASGASF----PAELHTSLIDPARPGEQIWVVIDVSARLEAENRIDQ 342 RS+ + +A G ++ P H I I +V D++ AE +I+ Sbjct: 325 RSNFEGHYLATYSDAEGWAYITCTPFHDHNGQIAGG-----IAIVQDITEHKAAEEKINN 379 Query: 343 LAFYDPVTQLPNKKLFMDRLRRGLDRRRTSGHAGAVFVMEIHRADLSYGSVKVDEMEQLL 402 LAFYDP+T LPN++L +DRL+ L SG GA+ +++ ++ D + LL Sbjct: 380 LAFYDPLTGLPNRRLLLDRLQHALASSARSGREGALLFIDLDNFKALNDTLGHDMGDLLL 439 Query: 403 IECARRFSSCITAEQTVARMEGEKFALGTEIRSNELAECIRYCEALAQRILDAFTDPQSL 462 + A+R +SC+ ++AR+ G++F + E E EA+ ++IL P L Sbjct: 440 RQVAQRLASCVREGDSIARLGGDEFVVMLEDLGGHDLEAAAQTEAVGEKILAMLGLPYQL 499 Query: 463 SAARFPCSVNLGINIVRDEQYGASELVMQAELAMVQSRAAGRNVFRFFDPAMQALANQRS 522 A + C+ ++G + + EL+ +A++AM Q++ AGRN RFFD MQ R Sbjct: 500 VAHEYRCTPSIGATLFSGHELAKEELLKRADIAMYQAKQAGRNTVRFFDQQMQDAVTARV 559 Query: 523 QLEAELRQAVARRQFIVYYQPQVTYEGDVVGAEALVRWQHPIRGIVSPTTFISLAEDMGL 582 LE EL +A+ R+QF ++YQ QV G +GAEAL+RW HP RG+V P FI +AE+ L Sbjct: 560 ALEGELHKALDRQQFRLHYQIQVDASGRPLGAEALIRWMHPERGLVPPDQFIGMAEETDL 619 Query: 583 MDEIGRQVLHRICSDLENWQREGLARDLVVAINVSAQEFKVDNFVYRFREIMREHHVPSH 642 + IG+ V+ C+ L+ WQ+ RDLV+A+NVSA +F +FV++ R ++ H + Sbjct: 620 ILPIGQWVMDTACAQLKTWQQHAPTRDLVLAVNVSATQFHQLDFVFQVRATVQRHAIDPK 679 Query: 643 SVKVELTESMMVDHIEDVITKMQALRSNEVSISLDDFGTGYSSLSYLGRFPIDQIKIDQT 702 +K+ELTESM++++IED I M AL+ V SLDDFGTGYSSL YL R P+DQIKIDQ+ Sbjct: 680 LLKLELTESMLLENIEDTIRTMNALKEIGVQFSLDDFGTGYSSLQYLKRLPLDQIKIDQS 739 Query: 703 FVREMQNDAAMASIIRSIIMLGQSLNLSIIAEGVETEQQRDFLHAQGCLLYQGYWYSKPI 762 FVR++ +D+ I+ +II + Q+L L +IAEGVETE+QR FL GC +QGY + KP+ Sbjct: 740 FVRDIASDSNDREIVGTIIAMAQNLYLDVIAEGVETEEQRQFLQDNGCTHFQGYLFGKPV 799 Query: 763 PGEQFADLLNTPGR 776 P EQF +L P R Sbjct: 800 PVEQFEAMLQ-PDR 812