BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0099.p (254 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777450.1| multidrug ABC transporter permease [Herbaspi... 502 e-140 ref|YP_001354982.1| ABC-2 type transporter protein [Janthinobact... 412 e-113 ref|YP_004751171.1| multidrug ABC transporter permease [Collimon... 409 e-112 ref|YP_001101303.1| ABC transporter membrane protein [Herminiimo... 403 e-110 emb|CBJ36649.1| putative ABC transporter permease protein, membr... 393 e-107 ref|YP_003751219.1| ABC transporter permease [Ralstonia solanace... 392 e-107 ref|ZP_04579894.1| ABC-2 type transporter [Oxalobacter formigene... 392 e-107 ref|YP_003744445.1| ABC transporter permease [Ralstonia solanace... 390 e-106 ref|YP_004229677.1| ABC transporter [Burkholderia sp. CCGE1001] ... 390 e-106 emb|CCA85321.1| putative ABC transporter permease protein,membra... 389 e-106 >ref|YP_003777450.1| multidrug ABC transporter permease [Herbaspirillum seropedicae SmR1] gb|ADJ65542.1| ABC-type multidrug transport system, permease component protein [Herbaspirillum seropedicae SmR1] Length = 254 Score = 502 bits (1293), Expect = e-140, Method: Compositional matrix adjust. Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MIGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPG 60 MIGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPG Sbjct: 1 MIGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPG 60 Query: 61 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVF 120 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVF Sbjct: 61 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVF 120 Query: 121 VVTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLA 180 VVTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLA Sbjct: 121 VVTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLA 180 Query: 181 GVFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAV 240 GVFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAV Sbjct: 181 GVFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAV 240 Query: 241 RMLKSGYKLRAGSH 254 RMLKSGYKLRAGSH Sbjct: 241 RMLKSGYKLRAGSH 254 >ref|YP_001354982.1| ABC-2 type transporter protein [Janthinobacterium sp. Marseille] gb|ABR90787.1| ABC-2 type transporter protein [Janthinobacterium sp. Marseille] Length = 251 Score = 412 bits (1058), Expect = e-113, Method: Compositional matrix adjust. Identities = 199/250 (79%), Positives = 223/250 (89%) Query: 1 MIGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPG 60 MIGF+TLFYKE+LRFWKVATQT+ API+TA+LYLLIFGHVL+D VQVYPGV YT FL+PG Sbjct: 1 MIGFQTLFYKEMLRFWKVATQTVAAPILTAVLYLLIFGHVLEDHVQVYPGVKYTAFLIPG 60 Query: 61 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVF 120 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLL PLSHWELF YV+AAVVRGL+VG GVF Sbjct: 61 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLPPLSHWELFSAYVMAAVVRGLVVGTGVF 120 Query: 121 VVTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLA 180 +VT WF + FVAP WIL+FA+LGA +LGTMGLIAGIWAEKFDQLAAFQNFLI+P TFL+ Sbjct: 121 IVTAWFADMSFVAPWWILIFAILGAAMLGTMGLIAGIWAEKFDQLAAFQNFLIMPATFLS 180 Query: 181 GVFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAV 240 GVFYS+HSLPPFWQ VSH NPFFYMIDGFRYGFFGQSD+ P+ S +VA F V L+ + + Sbjct: 181 GVFYSVHSLPPFWQTVSHMNPFFYMIDGFRYGFFGQSDVNPLVSSTVVAFFLVLLAGVGM 240 Query: 241 RMLKSGYKLR 250 +LKSGYKLR Sbjct: 241 SLLKSGYKLR 250 >ref|YP_004751171.1| multidrug ABC transporter permease [Collimonas fungivorans Ter331] gb|AEK60348.1| ABC-type multidrug transport system, permease component [Collimonas fungivorans Ter331] Length = 252 Score = 409 bits (1052), Expect = e-112, Method: Compositional matrix adjust. Identities = 197/250 (78%), Positives = 223/250 (89%) Query: 1 MIGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPG 60 MIGF+TLFYKE+LRFWKVATQTI API+TA+LYLLIFGH L+D ++VYPGV YT FL+PG Sbjct: 2 MIGFQTLFYKEVLRFWKVATQTIGAPILTAMLYLLIFGHTLKDHIEVYPGVQYTAFLIPG 61 Query: 61 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVF 120 LVMMSVLQNAFAN+SSSL QSK+TGNLVFVLLTPLSHWEL+G YVLA+VVRG+ VG GVF Sbjct: 62 LVMMSVLQNAFANTSSSLTQSKMTGNLVFVLLTPLSHWELYGAYVLASVVRGVAVGLGVF 121 Query: 121 VVTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLA 180 V+T WFG+L FVAP WI++FA LGA +LGTMGLIAG+WA+KFDQLA FQNFLI+P TFLA Sbjct: 122 VITAWFGNLSFVAPWWIVIFAFLGAALLGTMGLIAGVWADKFDQLAVFQNFLIMPATFLA 181 Query: 181 GVFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAV 240 GVFYSI SLPPFWQAVSH NPFFYMIDGFRYGFFGQSDI P+ SL I+ +F LS +AV Sbjct: 182 GVFYSIKSLPPFWQAVSHLNPFFYMIDGFRYGFFGQSDINPLISLLIICIFLALLSAVAV 241 Query: 241 RMLKSGYKLR 250 +MLK GYKLR Sbjct: 242 QMLKRGYKLR 251 >ref|YP_001101303.1| ABC transporter membrane protein [Herminiimonas arsenicoxydans] emb|CAL63182.1| ABC transporter, permease component [Herminiimonas arsenicoxydans] Length = 251 Score = 403 bits (1036), Expect = e-110, Method: Compositional matrix adjust. Identities = 198/250 (79%), Positives = 220/250 (88%) Query: 1 MIGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPG 60 M GF+TL YKE+LRFWKVATQT+ API+TA+LYLLIFGHVL++ VQVYPGVNYT FLVPG Sbjct: 1 MSGFQTLLYKEVLRFWKVATQTVAAPILTAVLYLLIFGHVLKNHVQVYPGVNYTTFLVPG 60 Query: 61 LVMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVF 120 LVMMSVLQNAFAN+SSSLIQSKITGNLVFVLLTPLSHWE FG YVLAA+VRGL VG GVF Sbjct: 61 LVMMSVLQNAFANASSSLIQSKITGNLVFVLLTPLSHWEFFGAYVLAAMVRGLAVGCGVF 120 Query: 121 VVTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLA 180 +VT WF + FVAP WI +F +LGA +LGT+GLIAG+WAEKFDQLAAFQNF+IVP TFL+ Sbjct: 121 LVTAWFADMSFVAPWWIAIFVILGAALLGTLGLIAGMWAEKFDQLAAFQNFVIVPATFLS 180 Query: 181 GVFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAV 240 GVFYSIHSLPP WQ VSHFNPFFYMIDGFRYGFFGQSD+ P+TS VA F + LS AV Sbjct: 181 GVFYSIHSLPPVWQTVSHFNPFFYMIDGFRYGFFGQSDVNPLTSCLAVAGFLLLLSGFAV 240 Query: 241 RMLKSGYKLR 250 +LKSGYKLR Sbjct: 241 YLLKSGYKLR 250 >emb|CBJ36649.1| putative ABC transporter permease protein, membrane component [Ralstonia solanacearum CMR15] Length = 262 Score = 393 bits (1010), Expect = e-107, Method: Compositional matrix adjust. Identities = 189/248 (76%), Positives = 219/248 (88%) Query: 3 GFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPGLV 62 GFRTL YKE+LRFWKV+ QT+ AP++TALLYLLIFGHVL+D VQV+ ++YT FL+PGLV Sbjct: 14 GFRTLLYKEVLRFWKVSFQTVAAPVLTALLYLLIFGHVLEDHVQVFGQISYTAFLIPGLV 73 Query: 63 MMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVFVV 122 MMSVLQNAFANSSSSLIQSKITGNLVF++L PLSHWE+FG YV+A+V+RGL VGAGV VV Sbjct: 74 MMSVLQNAFANSSSSLIQSKITGNLVFIMLPPLSHWEMFGAYVVASVIRGLAVGAGVLVV 133 Query: 123 TVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLAGV 182 T WF HL F PLWI+VFA+LGA +LGT+GLIAGIWAEKFDQLAAFQNFLIVP TFLAGV Sbjct: 134 TAWFAHLHFAQPLWIIVFAILGAAVLGTLGLIAGIWAEKFDQLAAFQNFLIVPATFLAGV 193 Query: 183 FYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAVRM 242 FYSIHSLPPFWQAVSH NPFFYMIDGFRYGFFG SD+ TSLG++ + V + +A++M Sbjct: 194 FYSIHSLPPFWQAVSHANPFFYMIDGFRYGFFGVSDVPVATSLGVMVIALVVVGGIALQM 253 Query: 243 LKSGYKLR 250 L++GYKLR Sbjct: 254 LRTGYKLR 261 >ref|YP_003751219.1| ABC transporter permease [Ralstonia solanacearum PSI07] emb|CBJ49910.1| putative ABC transporter permease protein, membrane component [Ralstonia solanacearum PSI07] emb|CCA81351.1| putative ABC transporter permease protein,membrane component [blood disease bacterium R229] Length = 262 Score = 392 bits (1008), Expect = e-107, Method: Compositional matrix adjust. Identities = 188/248 (75%), Positives = 219/248 (88%) Query: 3 GFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPGLV 62 GFRTL YKE+LRFWKV+ QT+ AP++TALLYLLIFGHVL+D VQV+ ++YT FL+PGLV Sbjct: 14 GFRTLLYKEVLRFWKVSFQTVAAPVLTALLYLLIFGHVLEDHVQVFGQISYTAFLIPGLV 73 Query: 63 MMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVFVV 122 MMSVLQNAFANSSSSLIQSKITGNLVF++L PLSHWE+FG YV+A+V+RGL VGAGV VV Sbjct: 74 MMSVLQNAFANSSSSLIQSKITGNLVFIMLPPLSHWEMFGAYVVASVIRGLAVGAGVLVV 133 Query: 123 TVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLAGV 182 T WF HL F PLWI+VFA+LGA +LGT+GLIAG+WAEKFDQLAAFQNFLIVP TFLAGV Sbjct: 134 TAWFAHLHFAQPLWIIVFAILGAAVLGTLGLIAGVWAEKFDQLAAFQNFLIVPATFLAGV 193 Query: 183 FYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAVRM 242 FYSIHSLPPFWQAVSH NPFFYMIDGFRYGFFG SD+ TSLG++ + V + +A++M Sbjct: 194 FYSIHSLPPFWQAVSHANPFFYMIDGFRYGFFGVSDVPVATSLGVMVIALVVVGGIALQM 253 Query: 243 LKSGYKLR 250 L++GYKLR Sbjct: 254 LRTGYKLR 261 >ref|ZP_04579894.1| ABC-2 type transporter [Oxalobacter formigenes OXCC13] gb|EEO30867.1| ABC-2 type transporter [Oxalobacter formigenes OXCC13] Length = 253 Score = 392 bits (1006), Expect = e-107, Method: Compositional matrix adjust. Identities = 187/247 (75%), Positives = 221/247 (89%) Query: 4 FRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPGLVM 63 FRTLFYKEILRFWKVATQTITAP++TALLYLLIFGH L+D VQVYPGV YT FLVPGLVM Sbjct: 6 FRTLFYKEILRFWKVATQTITAPVLTALLYLLIFGHALEDYVQVYPGVGYTAFLVPGLVM 65 Query: 64 MSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVFVVT 123 MS+LQN+FANSSSSLIQSKI G+LVF+LL+P+SHWEL+ Y+LA++VRGL+VG GVFVVT Sbjct: 66 MSLLQNSFANSSSSLIQSKINGSLVFILLSPISHWELYLAYMLASIVRGLVVGIGVFVVT 125 Query: 124 VWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLAGVF 183 +WF F +PLWI++FALLG+ ILGTMG+IAGIWA+K++QLA FQNFLI+P TFL+GVF Sbjct: 126 IWFAQPSFYSPLWIVLFALLGSAILGTMGIIAGIWADKYEQLATFQNFLIMPATFLSGVF 185 Query: 184 YSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAVRML 243 YSIH+LPP WQ +S FNPFFYM+DGFRYGFFG SDI P+TSL IV++FFV L+ LAV +L Sbjct: 186 YSIHTLPPVWQRISEFNPFFYMVDGFRYGFFGHSDINPLTSLIIVSIFFVFLAFLAVHLL 245 Query: 244 KSGYKLR 250 + GYKLR Sbjct: 246 QKGYKLR 252 >ref|YP_003744445.1| ABC transporter permease [Ralstonia solanacearum CFBP2957] emb|CBJ41801.1| putative ABC transporter permease protein, membrane component [Ralstonia solanacearum CFBP2957] Length = 262 Score = 390 bits (1001), Expect = e-106, Method: Compositional matrix adjust. Identities = 188/249 (75%), Positives = 218/249 (87%) Query: 2 IGFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPGL 61 IGFRTL YKE+LRFWKV+ QT+ AP++TALLYLLIFGHVL+D VQV+ ++YT FL+PGL Sbjct: 13 IGFRTLLYKEVLRFWKVSFQTVAAPVLTALLYLLIFGHVLEDHVQVFGQISYTAFLIPGL 72 Query: 62 VMMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVFV 121 VMMSVLQNAFANSSSSLIQSKITGNLVF++L PLS WE+FG YV+A+V+RGL VGAGV Sbjct: 73 VMMSVLQNAFANSSSSLIQSKITGNLVFIMLPPLSDWEMFGAYVVASVIRGLAVGAGVLA 132 Query: 122 VTVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLAG 181 VT WF HL F PLWI+VFA+LGA +LGT+GLIAGIWAEKFDQLAAFQNFLIVP TFLAG Sbjct: 133 VTAWFAHLHFAQPLWIIVFAILGAAVLGTLGLIAGIWAEKFDQLAAFQNFLIVPATFLAG 192 Query: 182 VFYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAVR 241 VFYSIHSLPPFWQAVSH NPFFYMIDGFRYGFFG SD+ TSLG++ + V + +A++ Sbjct: 193 VFYSIHSLPPFWQAVSHANPFFYMIDGFRYGFFGVSDVPVATSLGVMVIALVVVGGIALQ 252 Query: 242 MLKSGYKLR 250 ML++GYKLR Sbjct: 253 MLRTGYKLR 261 >ref|YP_004229677.1| ABC transporter [Burkholderia sp. CCGE1001] gb|ADX56617.1| ABC-2 type transporter [Burkholderia sp. CCGE1001] Length = 254 Score = 390 bits (1001), Expect = e-106, Method: Compositional matrix adjust. Identities = 193/248 (77%), Positives = 216/248 (87%) Query: 3 GFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPGLV 62 GF TLFYKEILRFWKV+ QT+ API+TALLYL IFGH L++ VQVYPGV YT FLVPGLV Sbjct: 6 GFGTLFYKEILRFWKVSFQTVLAPIITALLYLTIFGHALRNHVQVYPGVEYTSFLVPGLV 65 Query: 63 MMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVFVV 122 MMSVLQNAFANSSSSLIQSKITGNLVFVLL PLSH+E+F YVLAAV RGL VG GVF+V Sbjct: 66 MMSVLQNAFANSSSSLIQSKITGNLVFVLLPPLSHYEMFAAYVLAAVARGLAVGFGVFIV 125 Query: 123 TVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLAGV 182 T+WF + F APL+I++FA+ GAGILGT+GLIAGIWAEKFDQLAAFQNFLI+PLTFL+GV Sbjct: 126 TIWFVPVSFAAPLYIILFAICGAGILGTLGLIAGIWAEKFDQLAAFQNFLIMPLTFLSGV 185 Query: 183 FYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAVRM 242 FYS H+LPP W+ VS NPFFYMIDGFRYGFFG SDI P+ SL IVA FFV L+ +A+RM Sbjct: 186 FYSTHTLPPVWREVSRLNPFFYMIDGFRYGFFGMSDINPLASLAIVAGFFVVLAVVAMRM 245 Query: 243 LKSGYKLR 250 L SGYKLR Sbjct: 246 LASGYKLR 253 >emb|CCA85321.1| putative ABC transporter permease protein,membrane component [Ralstonia syzygii R24] Length = 262 Score = 389 bits (1000), Expect = e-106, Method: Compositional matrix adjust. Identities = 187/248 (75%), Positives = 218/248 (87%) Query: 3 GFRTLFYKEILRFWKVATQTITAPIVTALLYLLIFGHVLQDRVQVYPGVNYTGFLVPGLV 62 GFRTL YKE+LRFWKV+ QT+ AP++TALLYLLIFGHVL+D VQV+ ++YT FL+PGLV Sbjct: 14 GFRTLLYKEVLRFWKVSFQTVAAPVLTALLYLLIFGHVLEDHVQVFGQISYTAFLIPGLV 73 Query: 63 MMSVLQNAFANSSSSLIQSKITGNLVFVLLTPLSHWELFGGYVLAAVVRGLMVGAGVFVV 122 MMSVLQNAFANSSSSLIQSKITGNLVF++L PLSHWE+FG YV+A+V+RGL VGAGV VV Sbjct: 74 MMSVLQNAFANSSSSLIQSKITGNLVFIMLPPLSHWEMFGAYVVASVIRGLAVGAGVLVV 133 Query: 123 TVWFGHLDFVAPLWILVFALLGAGILGTMGLIAGIWAEKFDQLAAFQNFLIVPLTFLAGV 182 T WF HL F PLWI+VFA+LGA +LGT+GLIAG+WAEKFDQLAAFQNFLIVP TFLAGV Sbjct: 134 TAWFAHLHFAQPLWIIVFAILGAAVLGTLGLIAGVWAEKFDQLAAFQNFLIVPATFLAGV 193 Query: 183 FYSIHSLPPFWQAVSHFNPFFYMIDGFRYGFFGQSDIAPMTSLGIVAVFFVALSTLAVRM 242 FYSIHSLP FWQAVSH NPFFYMIDGFRYGFFG SD+ TSLG++ + V + +A++M Sbjct: 194 FYSIHSLPAFWQAVSHANPFFYMIDGFRYGFFGVSDVPVATSLGVMVIALVVVGGIALQM 253 Query: 243 LKSGYKLR 250 L++GYKLR Sbjct: 254 LRTGYKLR 261