BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0106.p (791 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775897.1| two component hybrid sensor histidine kinase... 1551 0.0 ref|YP_002423327.1| PAS/PAC sensor hybrid histidine kinase [Meth... 269 1e-69 ref|YP_003070686.1| sensor hybrid histidine kinase with multiple... 269 1e-69 ref|YP_001927407.1| PAS/PAC sensor hybrid histidine kinase [Meth... 268 4e-69 ref|YP_002965559.1| sensor hybrid histidine kinase with multiple... 266 9e-69 ref|YP_001641699.1| PAS sensor protein [Methylobacterium extorqu... 265 3e-68 ref|YP_002542570.1| two component sensor kinase/response regulat... 234 5e-59 ref|YP_001414747.1| PAS/PAC sensor hybrid histidine kinase [Parv... 189 2e-45 ref|YP_001172466.1| sensor/response regulator hybrid [Pseudomona... 186 2e-44 gb|AEA83873.1| sensor/response regulator hybrid [Pseudomonas stu... 186 2e-44 >ref|YP_003775897.1| two component hybrid sensor histidine kinase/response regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ63989.1| two component hybrid sensor histidine kinase/response regulator protein [Herbaspirillum seropedicae SmR1] Length = 1278 Score = 1551 bits (4015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 764/783 (97%), Positives = 768/783 (98%), Gaps = 5/783 (0%) Query: 1 MADFSWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARS 60 MADFSWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARS Sbjct: 13 MADFSWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARS 72 Query: 61 MLYNDAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLAL 120 MLYNDAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLAL Sbjct: 73 MLYNDAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLAL 132 Query: 121 LAPPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDLLSDLMEQSP 180 LAPPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDLLSDLMEQSP Sbjct: 133 LAPPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDLLSDLMEQSP 192 Query: 181 SFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQAY 240 SFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPAR ALPELLDENLF+LLDRVYQTGQAY Sbjct: 193 SFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARMALPELLDENLFMLLDRVYQTGQAY 252 Query: 241 TERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLAEERLRIVD 300 TERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLAEERLRIVD Sbjct: 253 TERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLAEERLRIVD 312 Query: 301 RAGEIGIFEWFPDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPNLGTARIKEG 360 RAGEIGIFEWFPDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPNLGTARIKEG Sbjct: 313 RAGEIGIFEWFPDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPNLGTARIKEG 372 Query: 361 GSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSRYVGVAFDVTARKLMEQALAAS 420 GSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSRYVGVAFDVTARKLMEQALAAS Sbjct: 373 GSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSRYVGVAFDVTARKLMEQALAAS 432 Query: 421 EASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEKDVLGRPIHDVIL 480 EASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEKDVLGRPIHDVIL Sbjct: 433 EASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEKDVLGRPIHDVIL 492 Query: 481 QPSEETQSRTGCAVLRAAREGVSAHVDSENFLRVDGTSFPVQYQTHPVWQDGQLQGALCT 540 QPSEETQSRTGCAVLRAAREGVSAHVDSENFLRVDGTSFPVQYQTHPVWQDGQLQGALCT Sbjct: 493 QPSEETQSRTGCAVLRAAREGVSAHVDSENFLRVDGTSFPVQYQTHPVWQDGQLQGALCT 552 Query: 541 FVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVNQALCRMLGRSEEEML 600 FVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVNQALCRMLGRSEEEML Sbjct: 553 FVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVNQALCRMLGRSEEEML 612 Query: 601 GMTLADVTHPDDVPMNMSLFNRCIEDGRSFTLEKRYLRPDGSTFWVSSDISRIVDGEGRP 660 GMTLADVTHPDDVPMNMSLFNRCIEDGRSFTLEKRYLRPDGSTFWVSSDISRIVDGEGRP Sbjct: 613 GMTLADVTHPDDVPMNMSLFNRCIEDGRSFTLEKRYLRPDGSTFWVSSDISRIVDGEGRP 672 Query: 661 QAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSRAEAALRQMQKMEAVGQLTGG 720 QAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSRAEAALRQMQKMEAVGQLTGG Sbjct: 673 QAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSRAEAALRQMQKMEAVGQLTGG 732 Query: 721 VAHDFNNVLQIIGGNLQLLQSDPRLDERSRQRVRIAIGAVSQAVFAIAGLCAPAALAAAQ 780 VAHDFNNVLQIIGGNLQLLQSDPRLDERSRQRVRIAIGAV + + L LA A+ Sbjct: 733 VAHDFNNVLQIIGGNLQLLQSDPRLDERSRQRVRIAIGAVDRGAKLSSQL-----LAFAR 787 Query: 781 HQP 783 QP Sbjct: 788 RQP 790 >ref|YP_002423327.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium chloromethanicum CM4] gb|ACK85399.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium chloromethanicum CM4] Length = 1092 Score = 269 bits (688), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 230/761 (30%), Positives = 344/761 (45%), Gaps = 51/761 (6%) Query: 6 WLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSMLYND 65 +L G G A ++ DW A+PLG+P W L+ + +L S P L+VWG A LYND Sbjct: 13 FLDGGGEAGALIRGIDWAATPLGSPETWPAALKTLVGVMLGSQQPMLIVWGEAHVTLYND 72 Query: 66 AFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLALLAPPQ 125 +A G+ HP ALG + W + L A A + P+ Sbjct: 73 GYAPMCGARHPRALGQSFDEV--WHDIWDQVGPILSRAYAGEATHMDDIALTMHRNGYPE 130 Query: 126 AATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDL--LSDLMEQSPSFK 183 + + V + E C+ AS +H + + L EQSPSF Sbjct: 131 ETHFAFGYTPVRI----EDGTVAGMFCACSETTASVRAGRQMHAERERFARLFEQSPSFV 186 Query: 184 AVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQAYTER 243 AV+ GP+HVF N+AY +L R V+G+P R ALPE+ + F LLD V+ TG+ +T Sbjct: 187 AVLDGPDHVFAFANAAYRQLIAHRDVLGRPVREALPEIEGQGFFELLDEVFSTGRTHTAH 246 Query: 244 GARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERM-----LAEERLRI 298 GA + + R + LDFV+QP+++A G + G+F++G+DVTER+ LAE R Sbjct: 247 GAPVTILRVPGGVPERRFLDFVYQPMRDAAGTITGVFVDGSDVTERITGNAALAESEARF 306 Query: 299 VDRAGEIGIFEWF--PDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPN---LG 353 A + + W PD ++ RR + + E A L + E HP+ Sbjct: 307 RTMADDAPVMMWVTGPDGACQYLN---RRWYDFTGQNEAQALGLGWL--EAVHPDDRGWS 361 Query: 354 TARIKEGGSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSR-----YVGVAFDVT 408 +R+ EY + R DG RW + PR + Y+G D+ Sbjct: 362 GETFLRANARHEGFSLEYRLRRRDGVYRW-----AIDTASPRFAADGSFLGYIGSVVDIE 416 Query: 409 ARKLMEQALAASEASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEK 468 R+ E ALA SE +R ++S + G + D + G A + Sbjct: 417 ERRAAELALAESEERLRLA-------VESGEIGLWDFDPRAGTLFWPPRIKAMFGLAPDA 469 Query: 469 DVLGRPIHDVILQPSEETQSRTGCAVLRAAREGVSAHVDSE--NFLRVDGTSFPVQYQTH 526 DV D L P + ++R A A A D E R DGT V + Sbjct: 470 DVTLDDFADG-LHPDD--RARVTAAFAAALDPVARAFYDEEFRAIGRADGTVRWVAAKGR 526 Query: 527 PVWQ-DGQLQGALCTFVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVN 585 V+ +G+ + + +D+T R+ + L + RL A+ + A+ +D + +N Sbjct: 527 GVFDAEGRCLRGVGSAIDITARKATEERLVEATRRLDAVLDNATQAIFMMDERQHCAYMN 586 Query: 586 QALCRMLGRSEEEMLGMTLADVTH---PDD--VPMNMSLFNRCIEDGRSFTLEKRYLRPD 640 +A R+ G S +E G L DV H PD P++ ++ + ++ ++ D Sbjct: 587 RAAERLTGYSLDETHGKALHDVVHHTRPDGSPYPLHECPIDQAFPENNQEQGQEIFVHRD 646 Query: 641 GSTFWVSSDISRIVDGEGRPQAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSR 700 GS + V+ S I D G P + + +I RA+ L N +LEQ+V E R Sbjct: 647 GSFYPVAFTASPIRDEGGTPIGTVIEARNIEGELRAKAQLEAFNASLEQQVAARTAELMR 706 Query: 701 AEAALRQMQKMEAVGQLTGGVAHDFNNVLQIIGGNLQLLQS 741 E ALRQ QKMEAVGQLTGG+AHDFNN+L I G+L+LLQ+ Sbjct: 707 TEEALRQSQKMEAVGQLTGGLAHDFNNLLTGITGSLELLQT 747 >ref|YP_003070686.1| sensor hybrid histidine kinase with multiple PAS/PAC and response regulator receiver domains [Methylobacterium extorquens DM4] emb|CAX26874.1| putative sensor hybrid histidine kinase with multiple PAS/PAC and response regulator receiver domains [Methylobacterium extorquens DM4] Length = 1092 Score = 269 bits (688), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 229/761 (30%), Positives = 344/761 (45%), Gaps = 51/761 (6%) Query: 6 WLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSMLYND 65 +L G G A ++ DW A+PLG+P W L+ + +L S P L+VWG A LYND Sbjct: 13 FLDGGGEAGALIRGIDWAATPLGSPEAWPAALKTLVGVMLGSQQPMLIVWGEAHVTLYND 72 Query: 66 AFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLALLAPPQ 125 +A G+ HP ALG P + W + L A A + P+ Sbjct: 73 GYAPMCGARHPRALGQPFDEV--WHDIWDQVGPILSRAYAGEATHMDDIALTMHRNGYPE 130 Query: 126 AATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDL--LSDLMEQSPSFK 183 + + V + E C+ AS +H + + L EQSPSF Sbjct: 131 ETHFAFGYTPVRI----EDGTVAGMFCACSETTASVRAGRQMHAERERFARLFEQSPSFV 186 Query: 184 AVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQAYTER 243 AV+ GP+H F N+AY +L R V+G+P R ALPE+ + F LLD V+ +G+ +T Sbjct: 187 AVLDGPDHAFAFANAAYRQLIAHRDVLGRPVREALPEIEGQGFFELLDEVFSSGRTHTAH 246 Query: 244 GARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERM-----LAEERLRI 298 GA + + R + LDFV+QP+++A G + G+F++G+DVTER+ LAE R Sbjct: 247 GAPVTILRVPGGVPERRFLDFVYQPMRDAAGTITGVFVDGSDVTERITGNAALAESEARF 306 Query: 299 VDRAGEIGIFEWF--PDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPN---LG 353 A + + W PD ++ RR + + E A L + E HP+ Sbjct: 307 RTMADDAPVMMWVTGPDGACQYLN---RRWYDFTGQNEAQALGLGWL--EAVHPDDRGWS 361 Query: 354 TARIKEGGSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSR-----YVGVAFDVT 408 +R+ EY + R DG RW + PR + Y+G D+ Sbjct: 362 GDTFLRANARHEGFSLEYRLRRRDGVYRW-----AIDTASPRFAADGSFLGYIGSVVDIE 416 Query: 409 ARKLMEQALAASEASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEK 468 R+ E ALA SE +R ++S + G + D + G A + Sbjct: 417 ERRAAELALAESEERLRLA-------VESGEIGLWDFDPRAGTLFWPPRIKAMFGLAPDA 469 Query: 469 DVLGRPIHDVILQPSEETQSRTGCAVLRAAREGVSAHVDSE--NFLRVDGTSFPVQYQTH 526 DV D L P + ++R A A A D E R DGT V + Sbjct: 470 DVTLDDFADG-LHPDD--RARVTAAFAAALDPVARAFYDEEFRAIGRADGTVRWVAAKGR 526 Query: 527 PVWQ-DGQLQGALCTFVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVN 585 V+ +G+ + + +D+T R+ + L + RL A+ + A+ +D + +N Sbjct: 527 GVFDAEGRCLRGVGSAIDITARKATEERLVEATRRLDAVLDNATQAIFMMDERQHCAYMN 586 Query: 586 QALCRMLGRSEEEMLGMTLADVTH---PDD--VPMNMSLFNRCIEDGRSFTLEKRYLRPD 640 +A R+ G S +E G L DV H PD P++ ++ + ++ ++ D Sbjct: 587 RAAERLTGYSLDETHGKALHDVVHHTRPDGSPYPLHECPIDQAFPENNQEQGQEIFVHRD 646 Query: 641 GSTFWVSSDISRIVDGEGRPQAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSR 700 GS + V+ S I D G P + + +I RA+ L N +LEQ+V E R Sbjct: 647 GSFYPVAFTASPIRDEGGMPIGTVIEARNIEGELRAKAQLEAFNASLEQQVAARTAELMR 706 Query: 701 AEAALRQMQKMEAVGQLTGGVAHDFNNVLQIIGGNLQLLQS 741 E ALRQ QKMEAVGQLTGG+AHDFNN+L I G+L+LLQ+ Sbjct: 707 TEEALRQSQKMEAVGQLTGGLAHDFNNLLTGITGSLELLQT 747 >ref|YP_001927407.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium populi BJ001] gb|ACB82872.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium populi BJ001] Length = 1086 Score = 268 bits (684), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 233/766 (30%), Positives = 346/766 (45%), Gaps = 59/766 (7%) Query: 5 SWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSMLYN 64 S+L G G A ++ DW A+PLG P W L+ + +L S P L+VWG A LYN Sbjct: 6 SFLAGGGAAGALMRGLDWAATPLGPPETWPAALKTLVGVMLGSQQPMLIVWGEAHVTLYN 65 Query: 65 DAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLALLAPP 124 D +A G+ HP ALG P + W + +++ + + AG E + Sbjct: 66 DGYAPMCGARHPKALGRPFDEV--W----HDIWDQVEPILSRAYAGEATHMEDITFTMHR 119 Query: 125 QA--ATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTA----LLHTDLLSDLMEQ 178 + P+ D +G+ C + A + + L EQ Sbjct: 120 NGYPEETHFAFGYTPVRGED----GTVAGMFCACSETTAAVRAGRQMQAERERFARLFEQ 175 Query: 179 SPSFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQ 238 +PSF AV+ GP HVF N+AY L R ++G+P R ALPE+ + F LLD VY TG+ Sbjct: 176 APSFVAVLDGPHHVFAFANAAYRGLVAHRDILGKPVRAALPEVEGQGFFELLDEVYATGR 235 Query: 239 AYTERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERM-----LAE 293 ++T GA + L R + LDFV+QP+++A G + G+F++G+DVTER+ LAE Sbjct: 236 SHTAHGAPVTLLRVPGGVPEQRFLDFVYQPMRDASGTITGVFVDGSDVTERITGNAALAE 295 Query: 294 ERLRIVDRAGEIGIFEWFPDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGM-IDEQFHPN- 351 R A + + W D+ R W G+ T AQ +G+ E HP+ Sbjct: 296 SEARFRTMADDAPVMMWVTDAD--GACQYLNRRW-YEFTGQ-TEAQALGLGWLEAVHPDD 351 Query: 352 --LGTARIKEGGSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSR-----YVGVA 404 +R+ EY + R DG RW + PR + Y+G Sbjct: 352 RGWSGETFLTANARHEGFSLEYRLRRRDGAYRW-----AIDTASPRFAADGRFLGYIGSV 406 Query: 405 FDVTARKLMEQALAASEASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGY 464 D+ R+ E ALA SE +R ++S + G + D + G Sbjct: 407 VDIEERRAAELALAESEERLRLA-------VESGEIGLWDFDPRAGTLFWPPRIKAMFGL 459 Query: 465 AAEKDVLGRPIHDVILQPSEETQSRTGCAVLRAAREGVSAHVDSENFLRV---DGTSFPV 521 A E DV + D + ++R A A G A D E F V DGT V Sbjct: 460 APEADVT---LEDFSEGLHPDDRARVTAAFAAALDPGTRAFYD-EEFRTVGGADGTIRWV 515 Query: 522 QYQTHPVWQ-DGQLQGALCTFVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGR 580 + V+ +G + + +D+T R+ + L + RL A+ + A+ +D + Sbjct: 516 AAKGRGVFDAEGHCLRGVGSAIDITARKATEERLVEATRRLDAVLDNATQAIFMMDERQH 575 Query: 581 YLRVNQALCRMLGRSEEEMLGMTLADVTH---PDD--VPMNMSLFNRCIEDGRSFTLEKR 635 +N+A R+ G + EE G L DV H PD P++ ++ + E+ Sbjct: 576 CAYMNRAAERLTGYTLEETRGQALHDVVHHTRPDGSPYPLHECPIDQAFPENNQEQGEEI 635 Query: 636 YLRPDGSTFWVSSDISRIVDGEGRPQAMIAVSTDITERRRAEEALRELNDTLEQRVVEEI 695 ++ DGS + V+ S I D G P + + +I RA+ L N +LEQ+V Sbjct: 636 FVHRDGSFYPVAFTASPIRDEGGAPIGTVIEARNIEAELRAKAQLEAFNASLEQQVAART 695 Query: 696 LERSRAEAALRQMQKMEAVGQLTGGVAHDFNNVLQIIGGNLQLLQS 741 E R E ALRQ QKMEAVGQLTGG+AHDFNN+L I G+L+LLQ+ Sbjct: 696 AELMRTEEALRQSQKMEAVGQLTGGLAHDFNNLLTGITGSLELLQT 741 >ref|YP_002965559.1| sensor hybrid histidine kinase with multiple PAS/PAC and response regulator receiver domains [methylobacterium extorquens AM1] gb|ACS42282.1| putative sensor hybrid histidine kinase with multiple PAS/PAC and response regulator receiver domains [Methylobacterium extorquens AM1] Length = 1086 Score = 266 bits (681), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 229/761 (30%), Positives = 344/761 (45%), Gaps = 51/761 (6%) Query: 6 WLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSMLYND 65 +L G G A ++ DW A+PLG+P W L+ + +L S P L+VWG A LYND Sbjct: 7 FLDGGGEAGALIRGIDWAATPLGSPEAWPAALKTLVGVMLGSQQPMLIVWGEAHVTLYND 66 Query: 66 AFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLALLAPPQ 125 +A G+ HP ALG + W + L A A + P+ Sbjct: 67 GYAPMCGARHPRALGQAFDEV--WHDIWDQVGPILSRAYAGEGTHMDDIALTMHRNGYPE 124 Query: 126 AATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDL--LSDLMEQSPSFK 183 + + V + E C+ AS +H + + L EQSPSF Sbjct: 125 ETHFAFGYTPVRI----EDGTVAGMFCACSETTASVRAGRQMHAERERFARLFEQSPSFV 180 Query: 184 AVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQAYTER 243 AV+ GP+H F N+AY +L R V+G+P R ALPE+ + F LLD V+ TG+ +T Sbjct: 181 AVLDGPDHAFAFANAAYRQLIAHRDVLGRPVREALPEIEGQGFFELLDDVFSTGRTHTAH 240 Query: 244 GARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERM-----LAEERLRI 298 GA + + R + LDFV+QP+++A G + G+F++G+DVTER+ LAE R Sbjct: 241 GAPVTILRVPGGMPERRFLDFVYQPMRDAAGTITGVFVDGSDVTERITGNAALAESEARF 300 Query: 299 VDRAGEIGIFEWF--PDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPN---LG 353 A + + W PD ++ RR + + E A L + E HP+ Sbjct: 301 RTMADDAPVMMWVTGPDGACQYLN---RRWYDFTGQNEAQALGLGWL--EAVHPDDRGWS 355 Query: 354 TARIKEGGSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSR-----YVGVAFDVT 408 +R+ EY + R DG RW + PR + Y+G D+ Sbjct: 356 GDTFLRANARHEGFSLEYRLRRRDGVYRW-----AIDTASPRFAADGSFLGYIGSVVDIE 410 Query: 409 ARKLMEQALAASEASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEK 468 R+ E ALA SE +R ++S + G + D + G A + Sbjct: 411 ERRAAELALAESEERLRLA-------VESGEIGLWDFDPRAGTLFWPPRIKAMFGLAPDA 463 Query: 469 DVLGRPIHDVILQPSEETQSRTGCAVLRAAREGVSAHVDSE--NFLRVDGTSFPVQYQTH 526 DV D L P + ++R A A A D E R DGT V + Sbjct: 464 DVTLDDFADG-LHPDD--RARVTAAFAAALDPVARAFYDEEFRAIGRADGTVRWVAAKGR 520 Query: 527 PVWQ-DGQLQGALCTFVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVN 585 V+ +G+ + + +D+T R+ + L + RL A+ + A+ +D + +N Sbjct: 521 GVFDAEGRCLRGVGSAIDITARKATEERLVEATRRLDAVLDNATQAIFMMDERQHCAYMN 580 Query: 586 QALCRMLGRSEEEMLGMTLADVTH---PDD--VPMNMSLFNRCIEDGRSFTLEKRYLRPD 640 +A R+ G S +E G L DV H PD P++ ++ + ++ ++ D Sbjct: 581 RAAERLTGYSLDETHGKALHDVVHHTRPDGSPYPLHECPIDQAFPENNQEQGQEIFVHRD 640 Query: 641 GSTFWVSSDISRIVDGEGRPQAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSR 700 GS + V+ S I D G P + + +I RA+ L N +LEQ+V+ E R Sbjct: 641 GSFYPVAFTASPIRDEGGTPIGTVIEARNIEGELRAKAQLEAFNASLEQQVLARTAELMR 700 Query: 701 AEAALRQMQKMEAVGQLTGGVAHDFNNVLQIIGGNLQLLQS 741 E ALRQ QKMEAVGQLTGG+AHDFNN+L I G+L+LLQ+ Sbjct: 701 TEEALRQSQKMEAVGQLTGGLAHDFNNLLTGITGSLELLQT 741 >ref|YP_001641699.1| PAS sensor protein [Methylobacterium extorquens PA1] gb|ABY32628.1| PAS sensor protein [Methylobacterium extorquens PA1] Length = 1086 Score = 265 bits (676), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 229/761 (30%), Positives = 342/761 (44%), Gaps = 51/761 (6%) Query: 6 WLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSMLYND 65 +L G G A ++ DW A+PLG+P W L+ + +L S P L+VWG A LYND Sbjct: 7 FLDGGGEAGALIRGIDWAATPLGSPEAWPAALKTLVGVMLGSQQPMLIVWGEAHVTLYND 66 Query: 66 AFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAPQQAECLALLAPPQ 125 +A G+ HP ALG + W + L A A + P+ Sbjct: 67 GYAPMCGARHPRALGQAFDEV--WHDIWDQVGPILSRAYAGEGTHMDDIALTMHRNGYPE 124 Query: 126 AATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDL--LSDLMEQSPSFK 183 + + V + E C+ AS +H + + L EQSPSF Sbjct: 125 ETHFAFGYTPVRI----EDGTVAGMFCACSETTASVRAGRQMHAERERFARLFEQSPSFV 180 Query: 184 AVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQAYTER 243 AV+ GP+H F N+AY +L R V+G+P R ALPE+ + F LLD V+ TG+ +T Sbjct: 181 AVLDGPDHAFAFANAAYRQLIAHRDVLGRPVREALPEIEGQGFFELLDDVFSTGRTHTAH 240 Query: 244 GARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERM-----LAEERLRI 298 GA + + R + LDFV+QP+++A G + G+F++G+DVTER+ LAE R Sbjct: 241 GAPVTILRVPGGMPERRFLDFVYQPMRDAAGTITGVFVDGSDVTERITGNAALAESEARF 300 Query: 299 VDRAGEIGIFEWF--PDSGRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPN---LG 353 A + + W PD ++ RR + + E A L + E HP+ Sbjct: 301 RTMADDAPVMMWVTGPDGACQYLN---RRWYDFTGQNEAQALGLGWL--EAVHPDDRGWS 355 Query: 354 TARIKEGGSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTGSR-----YVGVAFDVT 408 +R+ EY + R DG RW + PR + Y+G D+ Sbjct: 356 GDTFLRANARHEGFSLEYRLRRRDGVYRW-----AIDTASPRFAADGSFLGYIGSVVDIE 410 Query: 409 ARKLMEQALAASEASVRANNAFVRQLLDSTDQGFFSIDSAGIITLCNAAFLQLLGYAAEK 468 R+ E ALA SE +R ++S + G + D + G A Sbjct: 411 ERRAAELALAESEERLRLA-------VESGEIGLWDFDPRAGTLFWPPRIKAMFGLAPGA 463 Query: 469 DVLGRPIHDVILQPSEETQSRTGCAVLRAAREGVSAHVDSE--NFLRVDGTSFPVQYQTH 526 DV D L P + ++R A A A D E R DGT V + Sbjct: 464 DVTLDDFADG-LHPDD--RARVTAAFAAALDPVARAFYDEEFRAIGRADGTVRWVAAKGR 520 Query: 527 PVWQ-DGQLQGALCTFVDLTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVN 585 V+ +G+ + + +D+T R+ + L + RL A+ + A+ +D + +N Sbjct: 521 GVFDAEGRCLRGVGSAIDITARKATEERLVEATRRLDAVLDNATQAIFMMDERQHCAYMN 580 Query: 586 QALCRMLGRSEEEMLGMTLADVTH---PDD--VPMNMSLFNRCIEDGRSFTLEKRYLRPD 640 +A R+ G S +E G L DV H PD P++ ++ + ++ ++ D Sbjct: 581 RAAERLTGYSLDETHGKALHDVVHHTRPDGSPYPLHECPIDQAFPENNQEQGQEIFVHRD 640 Query: 641 GSTFWVSSDISRIVDGEGRPQAMIAVSTDITERRRAEEALRELNDTLEQRVVEEILERSR 700 GS + V+ S I D G P + + +I RA+ L N +LEQ+V E R Sbjct: 641 GSFYPVAFTASPIRDEGGTPIGTVIEARNIEGELRAKAQLEAFNASLEQQVAARTAELMR 700 Query: 701 AEAALRQMQKMEAVGQLTGGVAHDFNNVLQIIGGNLQLLQS 741 E ALRQ QKMEAVGQLTGG+AHDFNN+L I G+L+LLQ+ Sbjct: 701 TEEALRQSQKMEAVGQLTGGLAHDFNNLLTGITGSLELLQT 741 >ref|YP_002542570.1| two component sensor kinase/response regulator hybrid [Agrobacterium vitis S4] gb|ACM39385.1| two component sensor kinase/response regulator hybrid [Agrobacterium vitis S4] Length = 701 Score = 234 bits (597), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 192/600 (32%), Positives = 278/600 (46%), Gaps = 45/600 (7%) Query: 197 NSAYFKLFGDR--PVIGQPARTALPELLDENLFVLLDRVYQTGQAYTERGARLFLRRGVD 254 NSAY G R G+P A PEL N V+ +V G+ + R + RG Sbjct: 68 NSAYADFAGQRHSAFPGRPISEAWPELAALNSRVV--KVVLGGRTLSFRDRHAVIERGAG 125 Query: 255 SHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLAEERLRIVDRAGEIGIFEWFPDS 314 + L+ F P+ +A G G+ + D TER+ E+RL I +AG +G FEWFP S Sbjct: 126 P--EDVWLNLDFSPLLDANGIPAGVLVILKDTTERVRVEQRLEIAQQAGGVGTFEWFPAS 183 Query: 315 GRLSVSDRFRRLWGLPPEGEVTAAQLVGMIDEQFHPNLGTARIKEGGSRNPLEYTEYHIT 374 G L VS +R++WGL P+ +T L+ ++ G AR+ G NPLEY EY Sbjct: 184 GELHVSQEYRKVWGLDPDIRITDDLLISLLHPDDRAVSGPARL---GQSNPLEYAEYRRI 240 Query: 375 RPD-GQQRWLARKGEVVQDDPRTGSRYVGVAFDVTARKLMEQALAASEASVRANNAFVRQ 433 P G RW+AR+G+V+ + R+VG+AFD+T RK E L SE R Sbjct: 241 DPKTGDTRWIARRGQVISSERSGRRRFVGIAFDITDRKQAEVTLQKSEERWRG------- 293 Query: 434 LLDSTDQGFFSI----DSAG-----IITLCNAAFLQLLGYAAEKDVLGRPIHDVILQPSE 484 L + +GFF+ D+ G + N AF + G A + +G+P+ + I + Sbjct: 294 LFEQMHEGFFTAEVVRDAEGRVIDFVFIDINPAFERQTGLIAAQ-TIGQPVREAIPGVQD 352 Query: 485 ETQSRTGCAVLRA-AREGVSAHVDSENFLRVDGTSFPVQYQTHPVWQDGQLQGALCTFVD 543 E + G V AR+ E ++ G + Y+ H + AL F+D Sbjct: 353 ELIATYGEIVDTGQARQ-------FEVYIPALGNRW---YEAHARKVGPERFAAL--FLD 400 Query: 544 LTERRRGLQALSWSENRLRAIFNQASVCFSELDLQGRYLRVNQALCRMLGRSEEEMLGMT 603 +T R+ + + SE R R + G N + G S E++ G Sbjct: 401 ITIRKAAEKRVFESEERFRTLSQSMPNHVWTARSDGSLDWFNDQVFAYSGMSAEQLTGNG 460 Query: 604 LADVTHPDDVPMNMSLFNRCIEDGRSFTLEKRYLRPDGSTFWVSSDISRIVDGEGRPQAM 663 A + HPDD+ + + R + +E R R DG+ W + I G Sbjct: 461 WAAMVHPDDIDIAAQEWTEARAAARQYQVEFRLRRHDGAYRWHIARAVPIKPEGGGVAHW 520 Query: 664 IAVSTDITERRRAEEALRELNDTLEQRVVEEILERSRAEAALRQMQKMEAVGQLTGGVAH 723 I +TDI +++ AE AL LE RV E + + AL+Q QKME +G+LTGGVAH Sbjct: 521 IGTNTDIHDQKEAEAALEISAAKLEARVEERTAQLLEMQNALQQSQKMETIGKLTGGVAH 580 Query: 724 DFNNVLQIIGGNLQLLQSDPRLDERSRQRVRIAIGAVSQAVFAIAGLCAPAALAAAQHQP 783 DFNN+LQ+I GNL LL D +ER+ +RV A+ V + G A LA + QP Sbjct: 581 DFNNLLQVISGNLNLLAKDVAGNERAERRVTNALAGVIR-----GGKLASQLLAFGRRQP 635 >ref|YP_001414747.1| PAS/PAC sensor hybrid histidine kinase [Parvibaculum lavamentivorans DS-1] gb|ABS65090.1| PAS/PAC sensor hybrid histidine kinase [Parvibaculum lavamentivorans DS-1] Length = 966 Score = 189 bits (480), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 146/440 (33%), Positives = 209/440 (47%), Gaps = 41/440 (9%) Query: 6 WLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSMLYND 65 +L A+ I+ + DW A+PLG + W L+AT+ IL SP P + +WGG M+YND Sbjct: 8 FLLAGSEASDIIASFDWAATPLGPMSSWPSSLKATIGLILRSPVPIVTLWGGDGIMIYND 67 Query: 66 AFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGAP----QQAECLALL 121 A++ G HP G+ + GWP E A + + LAG Q L Sbjct: 68 AYSIFAGGRHPGIFGSKVRD--GWP----EVADFNDNVMKVGLAGGTLAYRDQELTLYRN 121 Query: 122 APPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDLLSDLMEQSPS 181 P+ D S +P E +P A V+ T R + + L + EQ+P Sbjct: 122 GEPEQVWMNLDYSPLP-DETGKPVGVIAI-VVETTRRVEAERQLERGFETLRRMFEQAPG 179 Query: 182 FKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRVYQTGQAYT 241 F A++ GPEH F VN+AY +L G R +G+P R ALPE++D+ LLDRV T Q Y Sbjct: 180 FVAILAGPEHTFVMVNNAYMQLIGHRDTLGKPIREALPEIVDQGFASLLDRVRDTQQPYI 239 Query: 242 ERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLA-------EE 294 RG R+ L+R + LDFVF P+ A V GIF++G+DVTER LA EE Sbjct: 240 GRGIRVLLQREPGMAPEERYLDFVFHPVAAARSDVRGIFVQGHDVTERRLAEIALRESEE 299 Query: 295 RLRIVDRAGEIGIFEWFPD-SGR-LSVSDRFRRLWGLPPEG--EVTAAQLVGMID-EQFH 349 R R+V + + + W D +G+ + ++D RR W + EG + A V D + H Sbjct: 300 RFRLVAESAPVML--WMGDETGKCIYLNDALRRFWNVTAEGVADFNWATTVHPDDSDTLH 357 Query: 350 PNLGTARIKEGGSRNPLEYTEYHITRPDGQQRWLARKGEVVQDDPRTG-----SRYVGVA 404 A + E R DG+ R + + PR G S +GV Sbjct: 358 GPFSAAM-----EAHTAFSVEVRFRRADGEYRIIRTNAQ-----PRFGPDGKFSGMIGVN 407 Query: 405 FDVTARKLMEQALAASEASV 424 DVT + E+AL A+ A++ Sbjct: 408 VDVTEMRRAEEALHAANANL 427 Score = 169 bits (427), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 113/328 (34%), Positives = 167/328 (50%), Gaps = 30/328 (9%) Query: 451 ITLCNAAFLQLLGYAAEKDVLGRPIHDVI--------------LQPSEETQSRTGCAVLR 496 + N A++QL+G+ +D LG+PI + + ++ +++ G VL Sbjct: 191 FVMVNNAYMQLIGH---RDTLGKPIREALPEIVDQGFASLLDRVRDTQQPYIGRGIRVLL 247 Query: 497 AAREGVSAHVDSENFLRVDGTSFPVQYQTHPVWQ-DGQLQGALCTFVDLTERRRGLQALS 555 G++ E +L + HPV ++G D+TERR AL Sbjct: 248 QREPGMAPE---ERYL---------DFVFHPVAAARSDVRGIFVQGHDVTERRLAEIALR 295 Query: 556 WSENRLRAIFNQASVCFSELDLQGRYLRVNQALCRMLGRSEEEMLGMTLADVTHPDDVPM 615 SE R R + A V D G+ + +N AL R + E + A HPDD Sbjct: 296 ESEERFRLVAESAPVMLWMGDETGKCIYLNDALRRFWNVTAEGVADFNWATTVHPDDSDT 355 Query: 616 NMSLFNRCIEDGRSFTLEKRYLRPDGSTFWVSSDISRIVDGEGRPQAMIAVSTDITERRR 675 F+ +E +F++E R+ R DG + ++ +G+ MI V+ D+TE RR Sbjct: 356 LHGPFSAAMEAHTAFSVEVRFRRADGEYRIIRTNAQPRFGPDGKFSGMIGVNVDVTEMRR 415 Query: 676 AEEALRELNDTLEQRVVEEILERSRAEAALRQMQKMEAVGQLTGGVAHDFNNVLQIIGGN 735 AEEAL N LEQRV E+ ERS+AE AL Q QKMEA+G+LTGGVAHDFNN+LQ++ GN Sbjct: 416 AEEALHAANANLEQRVAREVAERSKAEDALWQAQKMEAIGKLTGGVAHDFNNLLQVVSGN 475 Query: 736 LQLLQSDPRLDERSRQRVRIAIGAVSQA 763 LQLL D +ER+++R+ A+ V + Sbjct: 476 LQLLLKDLDGNERAQRRITNALAGVDRG 503 >ref|YP_001172466.1| sensor/response regulator hybrid [Pseudomonas stutzeri A1501] gb|ABP79624.1| probable sensor/response regulator hybrid [Pseudomonas stutzeri A1501] Length = 994 Score = 186 bits (471), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 119/314 (37%), Positives = 173/314 (55%), Gaps = 27/314 (8%) Query: 2 ADFSWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSM 61 A S+L G ++ DW+++PLG W L+ +LLSPTP +L+WG M Sbjct: 12 ASHSFLPDGGELGTLIRRFDWSSTPLGPLRDWPQSLKTVTAMLLLSPTPIVLLWGERGIM 71 Query: 62 LYNDAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGA--PQQAECLA 119 +YNDA++ GS HP LG+ + GWP E A + LAG + + LA Sbjct: 72 IYNDAYSGFAGSRHPQLLGSEVRL--GWP----EVADFNDHVMKVGLAGGTLSYKDQELA 125 Query: 120 LLAPPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDL------LS 173 L + A A +L P++ DE QAQ +GV+ + + + L +L L Sbjct: 126 LYRNGRPARAWMNLDYSPVF--DE--QAQPAGVIAMVVETT--ERVLAERELQGQQARLQ 179 Query: 174 DLMEQSPSFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRV 233 + EQ+P A++RGPEHVFE VN AY +L G+R +IG+P R ALPE+ + +LDRV Sbjct: 180 QMFEQAPGMMAMLRGPEHVFEMVNPAYCRLVGEREIIGKPVRDALPEVERQGFIEILDRV 239 Query: 234 YQTGQAYTERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLA- 292 Y++G+A+ G + L+R + + VLDFVFQP+ + +G V GIF+EG+DVTER A Sbjct: 240 YRSGEAFVGSGIHIGLQRTRGAAEEDRVLDFVFQPVTDIDGNVGGIFVEGHDVTERARAD 299 Query: 293 ------EERLRIVD 300 E+RLR +D Sbjct: 300 LALRENEQRLRFLD 313 >gb|AEA83873.1| sensor/response regulator hybrid [Pseudomonas stutzeri DSM 4166] Length = 993 Score = 186 bits (471), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 119/314 (37%), Positives = 173/314 (55%), Gaps = 27/314 (8%) Query: 2 ADFSWLRGAGPAAQILTASDWTASPLGAPAQWSPMLRATLNQILLSPTPSLLVWGGARSM 61 A S+L G ++ DW+++PLG W L+ +LLSPTP +L+WG M Sbjct: 12 ASHSFLPDGGELGTLIRRFDWSSTPLGPLRDWPQSLKTVTAMLLLSPTPIVLLWGERGIM 71 Query: 62 LYNDAFAACLGSAHPAALGAPLTTIAGWPGTDAESAGRLQSAVLASLAGA--PQQAECLA 119 +YNDA++ GS HP LG+ + GWP E A + LAG + + LA Sbjct: 72 IYNDAYSGFAGSRHPQLLGSEVRL--GWP----EVADFNDHVMKVGLAGGTLSYKDQELA 125 Query: 120 LLAPPQAATARWDLSCVPLWELDEPAQAQASGVLCTFLRASGVQTALLHTDL------LS 173 L + A A +L P++ DE QAQ +GV+ + + + L +L L Sbjct: 126 LYRNGRPARAWMNLDYSPVF--DE--QAQPAGVIAMVVETT--ERVLAERELQGQQARLQ 179 Query: 174 DLMEQSPSFKAVVRGPEHVFERVNSAYFKLFGDRPVIGQPARTALPELLDENLFVLLDRV 233 + EQ+P A++RGPEHVFE VN AY +L G+R +IG+P R ALPE+ + +LDRV Sbjct: 180 QMFEQAPGMMAMLRGPEHVFEMVNPAYCRLVGEREIIGKPVRDALPEVERQGFIEILDRV 239 Query: 234 YQTGQAYTERGARLFLRRGVDSHFDGAVLDFVFQPIKNAEGKVDGIFIEGNDVTERMLA- 292 Y++G+A+ G + L+R + + VLDFVFQP+ + +G V GIF+EG+DVTER A Sbjct: 240 YRSGEAFVGSGIHIGLQRTRGAAEEDRVLDFVFQPVTDIDGNVGGIFVEGHDVTERARAD 299 Query: 293 ------EERLRIVD 300 E+RLR +D Sbjct: 300 LALRENEQRLRFLD 313