BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0084.p (330 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775918.1| D-lactate dehydrogenase [Herbaspirillum sero... 660 0.0 ref|YP_001637534.1| NAD-binding D-isomer specific 2-hydroxyacid ... 404 e-110 ref|YP_002420091.1| NAD-binding D-isomer specific 2-hydroxyacid ... 398 e-109 ref|ZP_05029329.1| D-isomer specific 2-hydroxyacid dehydrogenase... 390 e-106 ref|YP_002005574.1| fermentative d-lactate dehydrogenase, NAD-de... 386 e-105 ref|ZP_08425149.1| lactate dehydrogenase family dehydrogenase [L... 385 e-105 ref|YP_298338.1| D-lactate dehydrogenase [Ralstonia eutropha JMP... 382 e-104 ref|YP_726178.1| D-lactate dehydrogenase [Ralstonia eutropha H16... 379 e-103 ref|YP_001866017.1| D-isomer specific 2-hydroxyacid dehydrogenas... 377 e-102 ref|NP_484102.1| D-lactate dehydrogenase [Nostoc sp. PCC 7120] >... 376 e-102 >ref|YP_003775918.1| D-lactate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64010.1| D-lactate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 330 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/330 (99%), Positives = 330/330 (100%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV Sbjct: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI Sbjct: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD Sbjct: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT Sbjct: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT Sbjct: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 Query: 301 EEAIGQIMQTTIENLSAFAAGDNLGERLVA 330 EEAIGQIMQTTIENLSAFAAGD+LGERLVA Sbjct: 301 EEAIGQIMQTTIENLSAFAAGDDLGERLVA 330 >ref|YP_001637534.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Methylobacterium extorquens PA1] gb|ABY28463.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Methylobacterium extorquens PA1] Length = 335 Score = 404 bits (1038), Expect = e-110, Method: Compositional matrix adjust. Identities = 203/330 (61%), Positives = 251/330 (76%), Gaps = 1/330 (0%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 M+ AVFSA+ Y++ LL NA H+L + LE GTA LAAG AV+ FVND + V Sbjct: 1 MRVAVFSAKNYERALLDDLNAGQEHDLTYFDALLEPGTASLAAGFTAVSVFVNDSVNRDV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 L +LA+ G + V TR TGFNHID+ AA G+ V RV +YSP SVAEFAVGLL A+NRK+ Sbjct: 61 LRQLAQGGTKLVATRCTGFNHIDLEAAEEFGIRVVRVVNYSPNSVAEFAVGLLLALNRKV 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTREGNF LDGLMG DL +TV VIGTGKIG +F RIMAGFGC+++G DVHR+P+ Sbjct: 121 HRAYNRTREGNFRLDGLMGFDLVDRTVAVIGTGKIGTIFGRIMAGFGCRVIGFDVHRSPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 F+ +GGRYVE + A DVIS+HCPLT T ++V+A++L K G +L+NTSRGGL+DT Sbjct: 181 FERIGGRYVEAAGVEEA-DVISMHCPLTPETYHIVDARTLGRVKKGALLINTSRGGLIDT 239 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +AAI ALKSGRL GLAIDVYEQEA LF++DLSST+I DDVIQRL+SFPNVIVTGHQAFFT Sbjct: 240 DAAIDALKSGRLGGLAIDVYEQEAELFYRDLSSTVIPDDVIQRLISFPNVIVTGHQAFFT 299 Query: 301 EEAIGQIMQTTIENLSAFAAGDNLGERLVA 330 +EA+G I+ TT++++S AG L + A Sbjct: 300 QEALGTILGTTLKSISELEAGHPLTNEVAA 329 >ref|YP_002420091.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Methylobacterium chloromethanicum CM4] gb|ACK82163.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Methylobacterium chloromethanicum CM4] Length = 335 Score = 398 bits (1022), Expect = e-109, Method: Compositional matrix adjust. Identities = 200/330 (60%), Positives = 249/330 (75%), Gaps = 1/330 (0%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 M+ AVFSA+ Y++ LL N H+L + LE GTA LAAG AV+ FVND + V Sbjct: 1 MRVAVFSAKNYERALLDDLNVGQEHDLTYFDALLEPGTASLAAGFTAVSVFVNDSVNRDV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 L +LA+ G + V TR TGFNHID+ AA G+ V RV +YSP SVAEFAVGLL A+NRK+ Sbjct: 61 LRQLAQGGTKLVATRCTGFNHIDLEAAEEFGIRVVRVVNYSPNSVAEFAVGLLLALNRKV 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTREGNF LDGLMG DL +TV VIGTGKIG +F RIMAGFGC+++G DVHR+P+ Sbjct: 121 HRAYNRTREGNFRLDGLMGFDLVDRTVAVIGTGKIGTIFGRIMAGFGCRVIGFDVHRSPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 F+ +GGRYV+ + A DVIS+HCPLT T ++V+A++L K G +L+NTSRGGL+DT Sbjct: 181 FERIGGRYVDAAGVEEA-DVISMHCPLTPETYHIVDARTLGRVKKGALLINTSRGGLIDT 239 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +AAI ALKSGRL GLAIDVYEQEA LF++DLSST+I DDVIQRL+SFPNVIVTGHQAFFT Sbjct: 240 DAAIDALKSGRLGGLAIDVYEQEAELFYRDLSSTVIPDDVIQRLISFPNVIVTGHQAFFT 299 Query: 301 EEAIGQIMQTTIENLSAFAAGDNLGERLVA 330 +EA+ I+ TT++++S AG L + A Sbjct: 300 QEALETILGTTLKSISELEAGHPLTNEVAA 329 >ref|ZP_05029329.1| D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, putative [Microcoleus chthonoplastes PCC 7420] gb|EDX72754.1| D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, putative [Microcoleus chthonoplastes PCC 7420] Length = 339 Score = 390 bits (1003), Expect = e-106, Method: Compositional matrix adjust. Identities = 186/321 (57%), Positives = 234/321 (72%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AVF+ + YD+ L NA + H+LVF + RL T LA G AV F+ND L Sbjct: 1 MKVAVFNTKSYDRNFLETTNANYNHDLVFFEPRLTQETTALAVGFSAVCVFINDQLDKTT 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 L LA G + + TRS GFNHID+ AA G+TV RV YSPY+VAE VGL+ +NRKI Sbjct: 61 LRVLAAQGTKLIATRSAGFNHIDLNAAAEFGITVVRVPAYSPYAVAEHTVGLILTLNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R REGNF LDG MG DLHG+TVG+IGTGKIG L A+I+ GFGCQ+L D++ NPD Sbjct: 121 HRAYNRVREGNFSLDGFMGFDLHGRTVGIIGTGKIGFLVAQILHGFGCQLLAYDLYPNPD 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 +ALG +YV+ ELFA SD+ISLHCPLT TR+L+NAQSLA K G +L+NTSRG L+DT Sbjct: 181 CEALGVKYVDLQELFATSDIISLHCPLTPQTRHLINAQSLAQMKSGVMLINTSRGALIDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +A I ALKS ++ L +DVYEQE++LFF+DLS+ +I DDV QRL++FPNV++TGHQAFFT Sbjct: 241 QAVIDALKSRKIGYLGLDVYEQESNLFFEDLSTEVIEDDVFQRLLTFPNVLITGHQAFFT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 E+A+ I QTT+ N+S +G Sbjct: 301 EDALQNIAQTTLSNISDVESG 321 >ref|YP_002005574.1| fermentative d-lactate dehydrogenase, NAD-dependent [Cupriavidus taiwanensis LMG 19424] emb|CAQ69507.1| fermentative D-lactate dehydrogenase, NAD-dependent [Cupriavidus taiwanensis LMG 19424] Length = 331 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 195/330 (59%), Positives = 244/330 (73%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 M+ AVFSA+ YD+ L ANA GH+L + + L+ T LAAG AV FVND V Sbjct: 1 MEIAVFSAKSYDRQHLDAANAVEGHQLKYFEVPLDTETVGLAAGHGAVCIFVNDRADATV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LE L G R V R TGFN++D+ AA+ALG+ V RV DYSP SVAE AV LL AVNRKI Sbjct: 61 LEALGRGGTRLVALRCTGFNNVDLKAAQALGVKVVRVVDYSPNSVAEHAVALLMAVNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTR+ NF L+GLMG DL GKTV VIGTGKIG +FA+IM GFGC ++G D + +P+ Sbjct: 121 HRAYNRTRDFNFSLEGLMGFDLCGKTVAVIGTGKIGRVFAKIMVGFGCNVIGYDKYPSPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 F+ALGGRY + E+ A++D ISLHCPLT T +++NA++L+ AKPG +L+NTSRGGL+DT Sbjct: 181 FEALGGRYADEGEIGASADCISLHCPLTPETHHIINAETLSRAKPGALLINTSRGGLIDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 EA IAAL+SG+L GLAIDVYEQEA LFF+DLS TII D V+Q+LV+FPNVIVTGHQAF T Sbjct: 241 EAVIAALRSGQLGGLAIDVYEQEAGLFFRDLSGTIIDDSVLQQLVTFPNVIVTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAGDNLGERLVA 330 EA+ I +TT+ +++ F G +L + A Sbjct: 301 REAVMTICETTLRSVTEFERGKSLTNEVSA 330 >ref|ZP_08425149.1| lactate dehydrogenase family dehydrogenase [Lyngbya majuscula 3L] gb|EGJ35696.1| lactate dehydrogenase family dehydrogenase [Lyngbya majuscula 3L] Length = 332 Score = 385 bits (988), Expect = e-105, Method: Compositional matrix adjust. Identities = 176/321 (54%), Positives = 234/321 (72%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AVFS + YD+ L N+ +GHEL F + L+ T LA+GC AV FVND L G V Sbjct: 1 MKVAVFSTKVYDRQFLEAVNSQYGHELTFFEPHLDTQTTILASGCPAVCVFVNDSLNGQV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LEKLA+ G R + R GFN++DV A L + V RV YSPY++AE +GL+ A+NRKI Sbjct: 61 LEKLAQQGTRLIALRCAGFNNVDVTKATELDMIVVRVPAYSPYAIAEHTIGLMLALNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R REGNF LDGL+G D+HG+TVG++GTGKIGV+ A+I+ G GCQ++ D + NPD Sbjct: 121 HRAYSRVREGNFSLDGLLGFDMHGRTVGIVGTGKIGVVVAQILNGMGCQLVAYDPYPNPD 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 ALG +YVE ELFA SD+++LHCPLT +L+N+++L KPG +L+NTSRGGL+DT Sbjct: 181 CQALGVKYVELAELFAISDIVTLHCPLTTENYHLINSEALEQMKPGVMLINTSRGGLIDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +A IAALKS ++ LA+DVYE+E+ LFF+DLS+ +I DD+ QRL++FPNVI+T HQAF T Sbjct: 241 KAIIAALKSKKIGYLALDVYEEESELFFEDLSNEVIQDDIFQRLLTFPNVIITAHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 E A+ I +TT+ N++ F G Sbjct: 301 ENALHNIAETTLSNITNFEQG 321 >ref|YP_298338.1| D-lactate dehydrogenase [Ralstonia eutropha JMP134] gb|AAZ63494.1| 6-phosphogluconate dehydrogenase, NAD-binding protein:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein [Ralstonia eutropha JMP134] Length = 330 Score = 382 bits (982), Expect = e-104, Method: Compositional matrix adjust. Identities = 194/321 (60%), Positives = 238/321 (74%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AVFSA+ YD+ L AN A GH+L F L+ TA LAAG AV FVND V Sbjct: 1 MKAAVFSAKPYDREYLDAANVAEGHQLDFFDVPLDINTAGLAAGHGAVCIFVNDVADAAV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 L+ L G + R TGFN++D+ AA +LG+ V RV YSP SVAE AV LL A+NRKI Sbjct: 61 LDALRRGGTSLIALRCTGFNNVDLGAAASLGMKVVRVVTYSPNSVAEHAVALLLAINRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTR+ NF LDGLMG D GKTV V+GTGKIG +FARIM GFGC+++G D + +P+ Sbjct: 121 HRAYNRTRDFNFSLDGLMGFDFCGKTVAVVGTGKIGRVFARIMLGFGCEVIGYDAYPSPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 F+ALGGRY + E+ A++D+ISLHCPLT T +++NA +LA AKPG +LVNTSRGGL+DT Sbjct: 181 FEALGGRYAQPGEIGASADIISLHCPLTPQTHHIINADALARAKPGALLVNTSRGGLLDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 AAI AL+S +L GLA+DVYEQEA LFF+DLSSTII DDV+QRLVSFPNVIVTGHQAF T Sbjct: 241 AAAIDALQSRQLGGLALDVYEQEADLFFRDLSSTIIADDVMQRLVSFPNVIVTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 EA+ I QTT+ +++ F +G Sbjct: 301 REAVSTICQTTLRSMTEFESG 321 >ref|YP_726178.1| D-lactate dehydrogenase [Ralstonia eutropha H16] ref|YP_726179.1| D-lactate dehydrogenase [Ralstonia eutropha H16] emb|CAJ92810.1| D-Lactate dehydrogenase [Ralstonia eutropha H16] emb|CAJ92811.1| D-Lactate dehydrogenase [Ralstonia eutropha H16] Length = 331 Score = 379 bits (972), Expect = e-103, Method: Compositional matrix adjust. Identities = 188/324 (58%), Positives = 240/324 (74%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 M+ AVFSA+ YD+ L ANAA GH+L + + L+ T LAAG AV FVND V Sbjct: 1 MEIAVFSAKSYDRQHLDAANAAEGHQLKYFEVPLDNETVGLAAGHGAVCIFVNDRADATV 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LE L G + V R TGFN++D+ AA+ALG+ V RV DYSP +VAE A LL AVNRKI Sbjct: 61 LEALGRGGTKLVALRCTGFNNVDLKAAQALGIKVVRVVDYSPNAVAEHAAALLMAVNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA RTR+ NF L+GLMG DL GKTV VIGTGKIG +FA+IM GFGC ++G D + +P+ Sbjct: 121 HRAYNRTRDFNFSLEGLMGFDLCGKTVAVIGTGKIGRVFAKIMVGFGCNVIGYDKYPSPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 F+ALGGRY + E+ A++D ISLHCPLT T +++NA++L+ AKPG +L+NTSRGGL+DT Sbjct: 181 FEALGGRYADEGEIGASADCISLHCPLTPETHHIINAETLSRAKPGALLINTSRGGLIDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 EA I AL+SG+L GLAIDVYEQEA LFF+DLS I+ D V+Q+L++FPNVIVTGHQAF T Sbjct: 241 EAVIGALRSGQLGGLAIDVYEQEAGLFFRDLSGIIVDDSVLQQLITFPNVIVTGHQAFLT 300 Query: 301 EEAIGQIMQTTIENLSAFAAGDNL 324 EA+ I +TT+ +++ F +G L Sbjct: 301 REAVTTICETTLRSVTEFESGKPL 324 >ref|YP_001866017.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [Nostoc punctiforme PCC 73102] gb|ACC81074.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [Nostoc punctiforme PCC 73102] Length = 334 Score = 377 bits (969), Expect = e-102, Method: Compositional matrix adjust. Identities = 180/321 (56%), Positives = 231/321 (71%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AVFS + YD+ L+ N+ HELVF + RL TA LAAG AV FV+D + Sbjct: 1 MKVAVFSTKVYDRQFLSTVNSPTQHELVFFEPRLNRDTAILAAGFPAVCVFVHDQVDAPT 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 L+ LA G R V R GFN++D+ AA LG+TV RV YSPY VAE AVGL+ ++NRKI Sbjct: 61 LKLLASRGTRLVVLRCAGFNNVDLQAAADLGITVVRVPAYSPYGVAEHAVGLILSLNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R REGNF LDGL+G +LH +TVG++GTGKIG++ +IM GFGC +L DV+RNP+ Sbjct: 121 HRAYNRVREGNFSLDGLLGFNLHERTVGIVGTGKIGLILGQIMKGFGCNLLAYDVYRNPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 +ALGG+YVE ELFA SD+ISLHCPLT T +L+NA+++ KPG +L+NTSRG L+DT Sbjct: 181 LEALGGKYVELPELFANSDIISLHCPLTPETHHLINAEAIEQIKPGVMLINTSRGALIDT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +A I LKSG++ L +DVYEQE+ LFF+DLS II DD+ QRL +FPNV++TGHQAFFT Sbjct: 241 QAVIEGLKSGKIGYLGVDVYEQESELFFEDLSGEIIQDDIFQRLTTFPNVLITGHQAFFT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 EA+ I +TT N++ G Sbjct: 301 AEALHNIAETTFANIADVENG 321 >ref|NP_484102.1| D-lactate dehydrogenase [Nostoc sp. PCC 7120] dbj|BAB77582.1| D-lactate dehydrogenase [Nostoc sp. PCC 7120] Length = 341 Score = 376 bits (966), Expect = e-102, Method: Compositional matrix adjust. Identities = 177/321 (55%), Positives = 231/321 (71%) Query: 1 MKTAVFSARRYDQTLLARANAAHGHELVFLQDRLEAGTAQLAAGCQAVAAFVNDDLGGVV 60 MK AVFS + YD+ L ANA HEL F + RL TA LAAG AV FV+D + Sbjct: 1 MKVAVFSTKAYDRQFLEAANAPKHHELAFFEPRLNQDTAILAAGFPAVCVFVHDQVDAAT 60 Query: 61 LEKLAELGVRFVTTRSTGFNHIDVAAARALGLTVARVADYSPYSVAEFAVGLLQAVNRKI 120 LE LA G R + R GFN++D+ AA LG+TV RV YSPY VAE AVGL+ ++NRKI Sbjct: 61 LEILASRGTRLIVLRCAGFNNVDLKAANKLGVTVVRVPAYSPYGVAEHAVGLILSLNRKI 120 Query: 121 ARASMRTREGNFELDGLMGVDLHGKTVGVIGTGKIGVLFARIMAGFGCQILGSDVHRNPD 180 RA R REGNF LDGL+G +++G+TVG+IGTGKIG++ +IM GFGC++L DV+RNP+ Sbjct: 121 HRAYNRVREGNFALDGLLGFNINGRTVGIIGTGKIGLILGQIMKGFGCRLLAYDVYRNPE 180 Query: 181 FDALGGRYVERTELFAASDVISLHCPLTEATRYLVNAQSLALAKPGCILVNTSRGGLVDT 240 ++LGG YVE ELFA SD+ISLHCPL T +L+NA+++ KPG +L+NTSRG L+ T Sbjct: 181 MESLGGEYVELPELFANSDIISLHCPLMPQTHHLINAEAIEQVKPGVMLINTSRGALIHT 240 Query: 241 EAAIAALKSGRLRGLAIDVYEQEASLFFQDLSSTIITDDVIQRLVSFPNVIVTGHQAFFT 300 +A I LK+G++ L +DVYEQE+ LFF+DLS II DD+ QRL +FPNV++TGHQAFFT Sbjct: 241 QAVIEGLKTGKIGSLGVDVYEQESELFFEDLSGEIIQDDIFQRLTTFPNVLITGHQAFFT 300 Query: 301 EEAIGQIMQTTIENLSAFAAG 321 E+A+ I +TT+ N++ G Sbjct: 301 EDALRNIAETTLNNIADIEQG 321