BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0080.p (762 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775922.1| isocitrate dehydrogenase [Herbaspirillum ser... 1528 0.0 ref|YP_002008279.1| isocitrate dehydrogenase [nadp] (oxalosuccin... 1244 0.0 ref|YP_004682080.1| hypothetical protein CNE_2c18920 [Cupriavidu... 1229 0.0 ref|YP_841443.1| isocitrate dehydrogenase [NADP] [Ralstonia eutr... 1224 0.0 ref|YP_298398.1| isocitrate dehydrogenase NADP-dependent, monome... 1223 0.0 ref|YP_157459.1| isocitrate dehydrogenase isozyme 2, monomeric t... 1215 0.0 gb|AAZ39189.1| monomeric isocitrate dehydrogenase [Janthinobacte... 1207 0.0 ref|YP_001155150.1| isocitrate dehydrogenase, NADP-dependent [Po... 1207 0.0 emb|CAD32551.1| isocitrate dehydrogenase isozyme 2 [Cupriavidus ... 1204 0.0 ref|YP_003604457.1| isocitrate dehydrogenase, NADP-dependent [Bu... 1203 0.0 >ref|YP_003775922.1| isocitrate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64014.1| isocitrate dehydrogenase (NADP) protein [Herbaspirillum seropedicae SmR1] Length = 742 Score = 1528 bits (3957), Expect = 0.0, Method: Compositional matrix adjust. Identities = 738/742 (99%), Positives = 741/742 (99%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 +TTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD Sbjct: 1 MTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE Sbjct: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG Sbjct: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE Sbjct: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS Sbjct: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR Sbjct: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE Sbjct: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTLDGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRAR 480 EYGSHDKTFEIAQAGVARIVTLDGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRAR Sbjct: 421 EYGSHDKTFEIAQAGVARIVTLDGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRAR 480 Query: 481 LSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDT 540 LSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDT Sbjct: 481 LSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDT 540 Query: 541 ISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENH 600 ISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENH Sbjct: 541 ISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENH 600 Query: 601 LRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRG 660 LRWDSLGEFLALAVSIEEVGIKTGN++AKILAKTLDAATGKLLDNNKSPSPKTGELDNRG Sbjct: 601 LRWDSLGEFLALAVSIEEVGIKTGNSKAKILAKTLDAATGKLLDNNKSPSPKTGELDNRG 660 Query: 661 SHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLP 720 SHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLP Sbjct: 661 SHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLP 720 Query: 721 DREKTFAVMRPSTTLNQALETL 742 DREKTFAVMRPS TLNQALETL Sbjct: 721 DREKTFAVMRPSATLNQALETL 742 >ref|YP_002008279.1| isocitrate dehydrogenase [nadp] (oxalosuccinate decarboxylase) (idh) [Cupriavidus taiwanensis LMG 19424] emb|CAQ72225.1| Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) [Cupriavidus taiwanensis LMG 19424] Length = 745 Score = 1244 bits (3220), Expect = 0.0, Method: Compositional matrix adjust. Identities = 593/743 (79%), Positives = 658/743 (88%), Gaps = 1/743 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 ++T PTIIYTLTDEAP LAT + LPI++ FT AGI+V SDISVA RIL EFP++LT+ Sbjct: 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISVAGRILGEFPDFLTE 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 EQ+VPDNLA LG LTQ PD NIIKLPNISAS+ QL +AIRELQ +GYK+PDYPE+P T+E Sbjct: 61 EQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKTDE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKA+QKRY+K GSAVNPVLREGNSDRRAP AVKNYARKHPHSM +WSMASRTHVAHM Sbjct: 121 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMGEWSMASRTHVAHMKH 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKS+TLD+A DVKM+L+TKSG+TIVLKPK+SLQ GEIIDSMFMSKKALCA+YEE Sbjct: 181 GDFYHGEKSMTLDRARDVKMELITKSGKTIVLKPKVSLQDGEIIDSMFMSKKALCAFYEE 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 Q +DA +T ++LS+HVKATMMKVSHPIVFGHAV+ +YK+ F KH LF E+GVN NNG+ Sbjct: 241 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +YEKI +LP +K+ E++ DL A RP LAMVDSAKGI+NLHAPNDVIVDASMPAMIR Sbjct: 301 NLYEKIESLPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A G+ +DTKA++PESTFARIYQE+INFCKTNG FDPTTMGTVPNVGLMAQKAE Sbjct: 361 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFEIA+ GVA IV L G+VLL QNVE+GDIWRMCQVKDA +RDWVKLAVTRA Sbjct: 421 EYGSHDKTFEIAEDGVANIVDLATGEVLLTQNVEQGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R SGMPAVFWLDPYRPHEAELIKKV TYLKDHD +G DIQIMSQVRAMRYTLERVIRGLD Sbjct: 481 RNSGMPAVFWLDPYRPHEAELIKKVETYLKDHDTSGLDIQIMSQVRAMRYTLERVIRGLD 540 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV EN Sbjct: 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLALAVS+E+VGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR Sbjct: 601 HLRWDSLGEFLALAVSLEDVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 660 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GS FYLA+YWAQELAAQ DDAELA +FAPLA+ L +NEQKIV EL +VQG+ VDIGGYY Sbjct: 661 GSQFYLAMYWAQELAAQSDDAELAAKFAPLARTLTDNEQKIVGELAAVQGQPVDIGGYYQ 720 Query: 720 PDREKTFAVMRPSTTLNQALETL 742 PD K A MRPS TLN AL ++ Sbjct: 721 PDAAKLSAAMRPSQTLNAALASV 743 >ref|YP_004682080.1| hypothetical protein CNE_2c18920 [Cupriavidus necator N-1] gb|AEI80848.1| isocitrate dehydrogenase [NADP] [Cupriavidus necator N-1] Length = 757 Score = 1229 bits (3179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 588/743 (79%), Positives = 652/743 (87%), Gaps = 1/743 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 ++ PTIIYTLTDEAP LAT + LPI++ FT AGI+V SDISVA RIL EFPE+LT+ Sbjct: 13 MSNQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISVAGRILGEFPEFLTE 72 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 Q+VPDNLA LG LTQ PD NIIKLPNISAS+ QL +AIRELQ +GYK+PDYPE+P T+E Sbjct: 73 AQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKTDE 132 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKA+QKRY+K GSAVNPVLREGNSDRRAP AVKN+ARKHPHSM +WSMASRTHVAHM Sbjct: 133 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNFARKHPHSMGEWSMASRTHVAHMKH 192 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKS+TLDKA DVKM+LVTKSG+TIVLKPK+SL GEIIDSMFMSKKALC +YEE Sbjct: 193 GDFYHGEKSMTLDKARDVKMELVTKSGKTIVLKPKVSLLDGEIIDSMFMSKKALCDFYEE 252 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 Q +DA +T ++LS+HVKATMMKVSHPIVFGHAV+ +YK+ F KH LF E+GVN NNG+ Sbjct: 253 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 312 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +YEKI LP +K+ E++ DL A RP LAMVDSAKGI+NLHAPNDVIVDASMPAMIR Sbjct: 313 NLYEKIEALPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 372 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A G+ +DTKA++PESTFARIYQE+INFCKTNG FDPTTMGTVPNVGLMAQKAE Sbjct: 373 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 432 Query: 421 EYGSHDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFEIA+ GVA IV L G+VLL Q+VE+GDIWRMCQVKDA +RDWVKLAVTRA Sbjct: 433 EYGSHDKTFEIAEDGVANIVDLATGEVLLTQDVEQGDIWRMCQVKDAPIRDWVKLAVTRA 492 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R SGMPAVFWLDPYRPHEAELIKKV YLK +D TG DIQIMSQVRAMRYTLERVIRGLD Sbjct: 493 RNSGMPAVFWLDPYRPHEAELIKKVEAYLKGYDTTGLDIQIMSQVRAMRYTLERVIRGLD 552 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV EN Sbjct: 553 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 612 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLALAVS+E+VGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTG+LDNR Sbjct: 613 HLRWDSLGEFLALAVSLEDVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGQLDNR 672 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GS FYLA+YWAQELA Q DDAELA +FAPLAK L +NEQKIV EL +VQGK VDIGGYY+ Sbjct: 673 GSQFYLAMYWAQELAVQSDDAELATKFAPLAKTLTDNEQKIVGELGAVQGKPVDIGGYYM 732 Query: 720 PDREKTFAVMRPSTTLNQALETL 742 P+ +K A MRPS TLN AL T+ Sbjct: 733 PEADKLSAAMRPSQTLNAALSTV 755 >ref|YP_841443.1| isocitrate dehydrogenase [NADP] [Ralstonia eutropha H16] emb|CAJ96713.1| isocitrate dehydrogenase [NADP] [Ralstonia eutropha H16] Length = 745 Score = 1224 bits (3168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 583/743 (78%), Positives = 653/743 (87%), Gaps = 1/743 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 ++T PTIIYTLTDEAP LAT + LPI++ FT AGI+V SDISVA RIL EFPE+LT+ Sbjct: 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISVAGRILGEFPEFLTE 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 Q+VPDNLA LG LTQ PD NIIKLPNISAS+ QL +AIRELQ +GYK+PDYPE+P +E Sbjct: 61 AQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKNDE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKA+QKRY+K GSAVNPVLREGNSDRRAP AVKN+ARKHPHSM +WSMASRTHVAHM Sbjct: 121 EKAIQKRYSKCLGSAVNPVLREGNSDRRAPAAVKNFARKHPHSMGEWSMASRTHVAHMKH 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKS+TLD+A DVKM+LVTKSG+TIVLKPK+SL GEIIDSMFMSKKALC +YEE Sbjct: 181 GDFYHGEKSMTLDRARDVKMELVTKSGKTIVLKPKVSLLDGEIIDSMFMSKKALCDFYEE 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 Q +DA +T ++LS+HVKATMMKVSHPIVFGHAV+ +YK+ F KH LF E+GVN NNG+ Sbjct: 241 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +YEKI LP +K+ E++ DL A RP LAMVDSAKGI+NLHAPNDVIVDASMPAMIR Sbjct: 301 NLYEKIEALPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A G+ +DTKA++PESTFARIYQE+INFCKTNG FDPTTMGTVPNVGLMAQKAE Sbjct: 361 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFEIA+ GVA IV L G+VLL Q+VE+GDIWRMCQVKDA +RDWVKLAVTRA Sbjct: 421 EYGSHDKTFEIAEDGVANIVDLATGEVLLTQDVEQGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R SGMPAVFWLDPYRPHEAELIKKV TYLKD+D G DIQIMSQVRAMRYTLERVIRGLD Sbjct: 481 RNSGMPAVFWLDPYRPHEAELIKKVETYLKDYDTNGLDIQIMSQVRAMRYTLERVIRGLD 540 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV EN Sbjct: 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLALAVS+E+VGIKTGNA+AKILA+TLDAATGKLLDNNKSPSPKTG+LDNR Sbjct: 601 HLRWDSLGEFLALAVSLEDVGIKTGNAKAKILARTLDAATGKLLDNNKSPSPKTGQLDNR 660 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GS FYLA+YWAQELA Q +DAELA +FAPLA+ L +NEQKIV EL +VQG+ VDIGGYY+ Sbjct: 661 GSQFYLAMYWAQELAGQSEDAELAAKFAPLARTLTDNEQKIVGELGAVQGQPVDIGGYYM 720 Query: 720 PDREKTFAVMRPSTTLNQALETL 742 P+ +K A MRPS TLN AL T+ Sbjct: 721 PEADKLSAAMRPSQTLNAALSTV 743 >ref|YP_298398.1| isocitrate dehydrogenase NADP-dependent, monomeric type [Ralstonia eutropha JMP134] gb|AAZ63554.1| Isocitrate dehydrogenase NADP-dependent, monomeric type [Ralstonia eutropha JMP134] Length = 747 Score = 1223 bits (3164), Expect = 0.0, Method: Compositional matrix adjust. Identities = 586/747 (78%), Positives = 656/747 (87%), Gaps = 3/747 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 ++T PTIIYTLTDEAP LAT + LPI++ FT A ++VV SDISVA RIL EFPE+LT+ Sbjct: 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIRTFTKPADVNVVTSDISVAGRILGEFPEFLTE 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 EQ+VPDNLA LG LTQ PD NIIKLPNISAS+ QL +AI+ELQS+G+K+PDYPE+P T+E Sbjct: 61 EQRVPDNLAELGKLTQDPDTNIIKLPNISASLFQLTSAIKELQSKGFKVPDYPEDPKTDE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKA+QKRY+KV GSAVNPVLREGNSDRRAP AVKNYARKHPHSM +WSMASRTHVAHM Sbjct: 121 EKAIQKRYSKVLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMGEWSMASRTHVAHMKH 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKS+TLDKA +V+M+L TKSG+TIVLKPK+SLQ GEIIDSMFMSKKAL A+YE+ Sbjct: 181 GDFYHGEKSITLDKAREVRMELATKSGKTIVLKPKVSLQDGEIIDSMFMSKKALLAFYED 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 QM+DA +T ++LS+HVKATMMKVSHPIVFGHAV+ +YKD F KH KLF E+GVN NNG+ Sbjct: 241 QMEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGLV 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +Y KI LP++KK EV+ D+ A RP LAMVDSAKGI+NLHAPNDVIVDASMPAMIR Sbjct: 301 DLYTKIEQLPESKKEEVIRDMHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A G+T+DTK L+PESTFARIYQE+INFCKTNGAFDP TMGTVPNVGLMAQKAE Sbjct: 361 IGGKMWGADGRTKDTKCLIPESTFARIYQEIINFCKTNGAFDPVTMGTVPNVGLMAQKAE 420 Query: 421 EYGSHDKTFEIAQAGVARIV-TLDGQVL--LEQNVEEGDIWRMCQVKDAAVRDWVKLAVT 477 EYGSHDKTFEIA+ G ARIV G+VL L Q VE+GDIWRMCQVKDA +RDWVKLAVT Sbjct: 421 EYGSHDKTFEIAEDGEARIVDNATGEVLSALTQKVEQGDIWRMCQVKDAPIRDWVKLAVT 480 Query: 478 RARLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRG 537 RAR SGMPAVFWLD YRPHEAELIKKV TYLKD+D G DIQIMSQVRAMRYTLERVIRG Sbjct: 481 RARNSGMPAVFWLDAYRPHEAELIKKVETYLKDYDTKGLDIQIMSQVRAMRYTLERVIRG 540 Query: 538 LDTISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVG 597 LDTISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHVQQLV Sbjct: 541 LDTISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVE 600 Query: 598 ENHLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELD 657 ENHLRWDSLGEFLALAVS+EE+GIK+GNA+AK+LAKTLDAATGKLLDN KSPSPKTG+LD Sbjct: 601 ENHLRWDSLGEFLALAVSLEELGIKSGNAKAKVLAKTLDAATGKLLDNAKSPSPKTGQLD 660 Query: 658 NRGSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGY 717 NRGS FYLA+YWAQELAAQ +DA LA FAPLAK L +NE+ IV EL+ VQGK VDIGGY Sbjct: 661 NRGSQFYLAMYWAQELAAQTEDAALAATFAPLAKQLTDNEKTIVGELSDVQGKPVDIGGY 720 Query: 718 YLPDREKTFAVMRPSTTLNQALETL*G 744 Y+PD EK A+MRPS TLN AL+++ G Sbjct: 721 YMPDAEKLSAIMRPSKTLNAALDSVQG 747 >ref|YP_157459.1| isocitrate dehydrogenase isozyme 2, monomeric type, NADP-specific [Aromatoleum aromaticum EbN1] emb|CAI06558.1| Isocitrate dehydrogenase isozyme 2,monomeric type, NADP-specific [Aromatoleum aromaticum EbN1] Length = 745 Score = 1215 bits (3144), Expect = 0.0, Method: Compositional matrix adjust. Identities = 581/740 (78%), Positives = 645/740 (87%), Gaps = 1/740 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 +TT +PTIIYTLTDEAP LAT+SLLPI++ F AGI++ +SDISVAARILAEF +YLTD Sbjct: 1 MTTKSPTIIYTLTDEAPLLATYSLLPIIETFAQPAGINIAKSDISVAARILAEFSDYLTD 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 QKVPDNLA LG LTQ PD NIIKLPNISA++ QL AI ELQ +GY +P+YPE P T+E Sbjct: 61 AQKVPDNLAELGRLTQDPDTNIIKLPNISAAVQQLTTAIAELQQKGYAIPNYPETPKTDE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EK +++RY K GSAVNPVLREGNSDRRAP AVK YARKHPHSM +WSMASRTHVAHM Sbjct: 121 EKIIKQRYGKALGSAVNPVLREGNSDRRAPAAVKRYARKHPHSMGEWSMASRTHVAHMKS 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKS+TLD+A DVKMDL+T SG+TIVLKPK++L GEIIDSMFMSK ALCA+YEE Sbjct: 181 GDFYHGEKSMTLDRARDVKMDLITNSGKTIVLKPKVALLDGEIIDSMFMSKNALCAFYEE 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 QM+DA +T ++ S+HVKATMMKVSHPIVFGHAV+ +YK+ F KH KLF E+GVN NNGMS Sbjct: 241 QMEDARKTGVMFSLHVKATMMKVSHPIVFGHAVKIFYKEAFEKHGKLFDELGVNVNNGMS 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +YEKI LP++K+ E++ DL A RP LAMVDSAKGITNLHAPNDVIVDASMPAMIR Sbjct: 301 NLYEKIAPLPESKRDEIVRDLHACHEHRPELAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A GK +DTKA++PESTFARIYQEMINFCKTNG FDP TMGTVPNVGLMAQ+AE Sbjct: 361 IGGKMWGADGKPKDTKAVMPESTFARIYQEMINFCKTNGNFDPRTMGTVPNVGLMAQQAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFEI +AG ARIV + G+VLL QNVEEGDIWRMCQ KDAA+RDWVKLAV RA Sbjct: 421 EYGSHDKTFEIPEAGEARIVDIATGEVLLVQNVEEGDIWRMCQAKDAAIRDWVKLAVNRA 480 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R SGMP +FWLDPYRPHEAELIKKV TYLKDHD TG DIQIMSQVRAMRYTLERVIRGLD Sbjct: 481 RNSGMPTLFWLDPYRPHEAELIKKVETYLKDHDTTGLDIQIMSQVRAMRYTLERVIRGLD 540 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHVQQLV EN Sbjct: 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEEN 600 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLAL S+E++GIKTGN +AK+LA+TLD ATGKLLDN+KSPS KTGELDNR Sbjct: 601 HLRWDSLGEFLALTASLEDMGIKTGNDKAKLLARTLDEATGKLLDNDKSPSRKTGELDNR 660 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GSHFYLALYWAQ LAAQ DDAEL +FAP+AKALAENEQKIV+EL++ QG+ DIGGYYL Sbjct: 661 GSHFYLALYWAQALAAQDDDAELKSRFAPMAKALAENEQKIVDELHAPQGRPADIGGYYL 720 Query: 720 PDREKTFAVMRPSTTLNQAL 739 PD KT AVMRPS T N L Sbjct: 721 PDPAKTRAVMRPSATFNAIL 740 >gb|AAZ39189.1| monomeric isocitrate dehydrogenase [Janthinobacterium lividum] Length = 743 Score = 1207 bits (3123), Expect = 0.0, Method: Compositional matrix adjust. Identities = 575/743 (77%), Positives = 645/743 (86%), Gaps = 1/743 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 + T IIYTLTDEAP LAT+SLLPI+KKFTA AG+DVV SDISVAAR+LAEFPE+LTD Sbjct: 1 MATQKSKIIYTLTDEAPLLATYSLLPIIKKFTAPAGVDVVSSDISVAARVLAEFPEFLTD 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 QKVP+ LA LG LTQ+PD NIIKLPNISAS QL A +RELQ RGYKLPDYPE+ T+E Sbjct: 61 AQKVPNTLAELGKLTQNPDTNIIKLPNISASQGQLIACVRELQGRGYKLPDYPEDAKTDE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 +KAL+ RY K GS+VNPVLREGNSDRRAP AVK YARKHPHSM +WS +S+THV+HMH Sbjct: 121 DKALKARYGKCIGSSVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSQSSQTHVSHMHH 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKSLTL+KA DVKM+LVT SG+TIVLKPK+SLQAGEIIDSMFMSKKAL +YE+ Sbjct: 181 GDFYHGEKSLTLEKARDVKMELVTASGKTIVLKPKVSLQAGEIIDSMFMSKKALLEFYEK 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 ++ DAF+T ++ S+HVKATMMKVSHPIVFGH VR +YKD F KHA LF ++GVN NNGMS Sbjct: 241 EIDDAFKTGVMFSLHVKATMMKVSHPIVFGHCVRIFYKDAFAKHAALFDKLGVNVNNGMS 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +Y+KI TLP ++K EVL DL A A RP LAMVDSAKGITN H+PND+IVDASMPAMIR Sbjct: 301 NLYDKIETLPASQKDEVLKDLHACHANRPELAMVDSAKGITNFHSPNDIIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A G+ +D KA++PESTFARIYQEMI FCK +G FDP TMGTVPNVGLMAQ+AE Sbjct: 361 IGGKMWGADGRPKDVKAVMPESTFARIYQEMIGFCKWHGNFDPKTMGTVPNVGLMAQQAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTLD-GQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFE+ + G+A I L+ G+VLL Q VEEGDIWRMCQVKDA +RDWVKLAVTRA Sbjct: 421 EYGSHDKTFEVPEGGIANITDLETGEVLLTQTVEEGDIWRMCQVKDAPIRDWVKLAVTRA 480 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R SGMPAVFWLD YRPHE E+IKKV YLKDHD G DIQIMSQ RAMRYTLER RGLD Sbjct: 481 RNSGMPAVFWLDSYRPHENEVIKKVQVYLKDHDTKGLDIQIMSQTRAMRYTLERAFRGLD 540 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPI+ELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV EN Sbjct: 541 TISVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLALAVS+E++GIKTGNA+AKILAKTLD ATGKLLDNNKSPSP+TGELDNR Sbjct: 601 HLRWDSLGEFLALAVSLEDMGIKTGNAKAKILAKTLDEATGKLLDNNKSPSPRTGELDNR 660 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GSHFYLA+YWAQ LAAQKDDAELA FAP+AKALA+NE+KIV EL +VQGK+ DIGGYYL Sbjct: 661 GSHFYLAMYWAQALAAQKDDAELAAHFAPVAKALADNEEKIVAELKAVQGKETDIGGYYL 720 Query: 720 PDREKTFAVMRPSTTLNQALETL 742 PD KT AVMRPS +LN L+++ Sbjct: 721 PDPAKTEAVMRPSASLNAVLDSI 743 >ref|YP_001155150.1| isocitrate dehydrogenase, NADP-dependent [Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1] gb|ABP33586.1| isocitrate dehydrogenase, NADP-dependent [Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1] Length = 744 Score = 1207 bits (3123), Expect = 0.0, Method: Compositional matrix adjust. Identities = 570/733 (77%), Positives = 643/733 (87%) Query: 8 IIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTDEQKVPDN 67 IIYTLTDEAP LAT + LPI++ FTA AG+++V SDISVAARILAEF E LT EQKVPDN Sbjct: 8 IIYTLTDEAPLLATCAFLPIIRTFTAPAGVEIVNSDISVAARILAEFSECLTTEQKVPDN 67 Query: 68 LAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEEEKALQKR 127 LA LG +T PD NIIKLPNISAS+ QL AAI+ELQS+GYK+P++PE+P T+EEK+++ R Sbjct: 68 LAELGKMTLMPDTNIIKLPNISASVPQLLAAIKELQSKGYKIPNFPEDPKTDEEKSIRTR 127 Query: 128 YAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHGGDFYAGE 187 Y+K GS+VNPVLREGNSDRRAP AVK YARK+PHSM +WS ASRTHV+HMHGGDFY+ E Sbjct: 128 YSKCLGSSVNPVLREGNSDRRAPPAVKRYARKNPHSMGEWSQASRTHVSHMHGGDFYSSE 187 Query: 188 KSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEEQMQDAFE 247 KS+T+ KA DVKMDLVTKSG+TIVLKPK+SL AGEIIDSM MSKKALC +YE++++DA++ Sbjct: 188 KSMTMTKACDVKMDLVTKSGKTIVLKPKVSLLAGEIIDSMNMSKKALCEFYEKEIEDAYK 247 Query: 248 TDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMSGVYEKIN 307 T ++LS+HVKATMMKVSHPIVFGHAV+ +YKD F KHAKLF E+GVN NNGMS +YEKI Sbjct: 248 TGMMLSLHVKATMMKVSHPIVFGHAVKIFYKDAFEKHAKLFEELGVNANNGMSSLYEKIK 307 Query: 308 TLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIRAGGKMWN 367 TLP++K+ E++ DL A RP LAMVDSAKGITNLH+P+DVIVDASMPAMIR GGKMW Sbjct: 308 TLPESKREEIIQDLHACHEHRPALAMVDSAKGITNLHSPSDVIVDASMPAMIRVGGKMWG 367 Query: 368 AAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAEEYGSHDK 427 A G+ DTKA++PESTFARIYQEMINFCKT+G FDPTTMGTVPNVGLMAQ+AEEYGSHDK Sbjct: 368 ADGRLHDTKAVIPESTFARIYQEMINFCKTHGNFDPTTMGTVPNVGLMAQQAEEYGSHDK 427 Query: 428 TFEIAQAGVARIVTLDGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRARLSGMPAV 487 TFEI +AGVARIV DG VLLEQNVEEGDIWRMCQ KDA +RDWVKLAV RARLS PAV Sbjct: 428 TFEIPEAGVARIVADDGTVLLEQNVEEGDIWRMCQCKDAPIRDWVKLAVNRARLSNTPAV 487 Query: 488 FWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDTISVTGNI 547 FWLD YRPHEAELIKKVNTYLKD+DLTG DIQIMSQ RAMRYTLERVIRG DTISVTGNI Sbjct: 488 FWLDEYRPHEAELIKKVNTYLKDYDLTGVDIQIMSQTRAMRYTLERVIRGKDTISVTGNI 547 Query: 548 LRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENHLRWDSLG 607 LRDYLTDLFPIMELGTSAKMLSIVPLMAGGG+FETGAGGSAPKHVQQLV ENHLRWDSLG Sbjct: 548 LRDYLTDLFPIMELGTSAKMLSIVPLMAGGGLFETGAGGSAPKHVQQLVEENHLRWDSLG 607 Query: 608 EFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRGSHFYLAL 667 EFLALAVS+E++G KTGN + KILA+TLD ATG LLDNNKSPSP+TGELDNRGS FYLA+ Sbjct: 608 EFLALAVSLEDIGDKTGNNKVKILARTLDEATGTLLDNNKSPSPRTGELDNRGSQFYLAM 667 Query: 668 YWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLPDREKTFA 727 YWA+ LAAQ +D EL FAPLAKAL+ENE+KI E +VQGK VDIGGY++ D EK A Sbjct: 668 YWAKALAAQTEDKELQAYFAPLAKALSENEEKITAEFKAVQGKPVDIGGYFVADPEKCKA 727 Query: 728 VMRPSTTLNQALE 740 VMRPS T N AL+ Sbjct: 728 VMRPSQTFNAALK 740 >emb|CAD32551.1| isocitrate dehydrogenase isozyme 2 [Cupriavidus necator] Length = 745 Score = 1204 bits (3114), Expect = 0.0, Method: Compositional matrix adjust. Identities = 575/743 (77%), Positives = 647/743 (87%), Gaps = 1/743 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 ++T PTIIYTLTDEAP LAT + LPI++ FT AGI+V SDIS+A RIL EFPE+LT+ Sbjct: 1 MSTQQPTIIYTLTDEAPLLATSAFLPIIQTFTKPAGINVTTSDISMAGRILGEFPEFLTE 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 Q+VPDNLA LG LTQ PD NIIKLPNISAS+ QL +AIRELQ +GYK+PDYPE+P +E Sbjct: 61 AQRVPDNLAELGKLTQLPDTNIIKLPNISASVHQLVSAIRELQGKGYKVPDYPEDPKNDE 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKA+QKRY+K GSAVNPVLREGNSD RAP AVKN+ARKHPHSM +WSMASRTHVAHM Sbjct: 121 EKAIQKRYSKCLGSAVNPVLREGNSDPRAPAAVKNFARKHPHSMGEWSMASRTHVAHMKH 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 DFY GEKS+TLD+A DVKM+LVTKSG+TIVLKPK+SL GEIIDSMFMSKKALC +YEE Sbjct: 181 RDFYHGEKSMTLDRARDVKMELVTKSGKTIVLKPKVSLLDGEIIDSMFMSKKALCDFYEE 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 Q +DA +T ++LS+HVKATMMKVSHPIVFGHAV+ +YK+ F KH LF E+GVN NNG+ Sbjct: 241 QFEDARKTGVMLSLHVKATMMKVSHPIVFGHAVKIFYKEAFAKHGALFDELGVNVNNGLV 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +YEKI LP +K+ E++ DL A RP LAMVDSAKGI+NLHAPNDVIVDASMPAMIR Sbjct: 301 NLYEKIEALPSSKREEIIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 GGKMW A G+ +DTKA++PESTFARIYQE+INFCKTNG FDPTTMGTVPNVGLMAQKAE Sbjct: 361 IGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGNFDPTTMGTVPNVGLMAQKAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFEIA+ GV IV L G+VLL Q+VE+GDIWRM QVKDA +RDWVKLAVTRA Sbjct: 421 EYGSHDKTFEIAEDGVVNIVDLATGEVLLTQDVEQGDIWRMLQVKDAPIRDWVKLAVTRA 480 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R SGMPAVFWLDPYRPHEAELIKKV TYL D+D G DIQIMSQVRAMRYTLERVIRGLD Sbjct: 481 RNSGMPAVFWLDPYRPHEAELIKKVETYLIDYDTNGLDIQIMSQVRAMRYTLERVIRGLD 540 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV +N Sbjct: 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEDN 600 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLALAVS+E+VGIKTGN +AKILA+TLDAATGKLLDNNKSPSPKTG+LDNR Sbjct: 601 HLRWDSLGEFLALAVSLEDVGIKTGNGKAKILARTLDAATGKLLDNNKSPSPKTGQLDNR 660 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GS FYLA+YWAQELA Q +DAELA +FAPLA+ L +NEQKIV EL +VQG+ VDIGGYY+ Sbjct: 661 GSQFYLAMYWAQELAGQLEDAELAAKFAPLARTLTDNEQKIVGELGAVQGQPVDIGGYYM 720 Query: 720 PDREKTFAVMRPSTTLNQALETL 742 P+ +K A MRPS TLN AL T+ Sbjct: 721 PEADKLSAAMRPSQTLNAALSTV 743 >ref|YP_003604457.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia sp. CCGE1002] gb|ADG14946.1| isocitrate dehydrogenase, NADP-dependent [Burkholderia sp. CCGE1002] Length = 746 Score = 1203 bits (3113), Expect = 0.0, Method: Compositional matrix adjust. Identities = 575/743 (77%), Positives = 645/743 (86%), Gaps = 1/743 (0%) Query: 1 VTTGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTD 60 +TT PTIIYTLTDEAP LAT + LPI++ FT AGI+V SDISVA RIL EFPE+LT+ Sbjct: 1 MTTQQPTIIYTLTDEAPLLATAAFLPIIRTFTRPAGIEVETSDISVAGRILGEFPEFLTE 60 Query: 61 EQKVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEE 120 Q+VPDNLA LG LT PD NIIKLPNISAS+ QL +AI+ELQ++GYK+PDYPE+P T+ Sbjct: 61 AQRVPDNLAELGRLTSLPDTNIIKLPNISASVPQLTSAIKELQAKGYKVPDYPEDPKTDA 120 Query: 121 EKALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHG 180 EKA+++RY+K GSAVNPVLREGNSDRRAP AVKNYARKHPHSM +WSMASRTHVA M Sbjct: 121 EKAIRQRYSKCLGSAVNPVLREGNSDRRAPAAVKNYARKHPHSMTEWSMASRTHVATMRH 180 Query: 181 GDFYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEE 240 GDFY GEKS+TLD+A DVKM+LVTK+G+TIVLKPK++L+ GEIIDSMFMSKKAL A+YE+ Sbjct: 181 GDFYHGEKSMTLDRARDVKMELVTKNGKTIVLKPKVALEDGEIIDSMFMSKKALLAFYED 240 Query: 241 QMQDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMS 300 QM+DA +T ++LS+HVKATMMK+SHPIVFGHAV+ +YKD F KH KLF E+GVN NNG+ Sbjct: 241 QMEDARKTGMMLSLHVKATMMKISHPIVFGHAVKVFYKDAFAKHGKLFEELGVNVNNGLV 300 Query: 301 GVYEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIR 360 +YEKI LP++++ EV+ DL A RP LAMVDSAKGI+NLHAPNDVIVDASMPAMIR Sbjct: 301 NLYEKIEALPESQREEVIRDLHACHEHRPELAMVDSAKGISNLHAPNDVIVDASMPAMIR 360 Query: 361 AGGKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAE 420 AGGKMW A G+ +DTKA++PESTFARIYQE+INFCKTNGAFDP TMGTVPNVGLMAQKAE Sbjct: 361 AGGKMWGADGRPKDTKAVIPESTFARIYQEIINFCKTNGAFDPVTMGTVPNVGLMAQKAE 420 Query: 421 EYGSHDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRA 479 EYGSHDKTFE+ + G ARIV L G+VLL QNVE+GDIWRMC+VKDAA+RDWVKLAVTR Sbjct: 421 EYGSHDKTFEVPEDGEARIVDLASGEVLLTQNVEQGDIWRMCEVKDAAIRDWVKLAVTRV 480 Query: 480 RLSGMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLD 539 R S PAVFWLDPYRPHEAELIKKV YLKD+D TG DIQIMSQVRAMRYTLERV+RGLD Sbjct: 481 RNSRTPAVFWLDPYRPHEAELIKKVEAYLKDYDTTGLDIQIMSQVRAMRYTLERVVRGLD 540 Query: 540 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGEN 599 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV EN Sbjct: 541 TISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEEN 600 Query: 600 HLRWDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNR 659 HLRWDSLGEFLALAVS+EE+GIKTGN RAKILAKTLD ATGKLLDNN+SPSPKTGELDNR Sbjct: 601 HLRWDSLGEFLALAVSLEELGIKTGNNRAKILAKTLDTATGKLLDNNRSPSPKTGELDNR 660 Query: 660 GSHFYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYL 719 GS FYLA+YWAQELAAQ DDA LA QFAPLA L NEQ IV EL SVQG DIGGYY Sbjct: 661 GSQFYLAMYWAQELAAQTDDAALAAQFAPLATQLTANEQVIVAELASVQGAPADIGGYYK 720 Query: 720 PDREKTFAVMRPSTTLNQALETL 742 PD K VMRPS T N+AL+ + Sbjct: 721 PDFNKLEEVMRPSRTFNEALKAV 743