BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0002.p (561 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_972314.1| diguanylate cyclase [Acidovorax citrulli AAC00-... 431 e-118 ref|YP_004236358.1| diguanylate cyclase [Acidovorax avenae subsp... 421 e-115 ref|YP_349279.1| diguanylate cyclase [Pseudomonas fluorescens Pf... 416 e-114 ref|YP_002873133.1| putative GGDEF domain signaling protein [Pse... 399 e-109 ref|ZP_08402673.1| putative GGDEF domain signaling protein [Rubr... 393 e-107 ref|NP_903805.1| hypothetical protein CV_4135 [Chromobacterium v... 370 e-100 ref|YP_001099097.1| hypothetical protein HEAR0777 [Herminiimonas... 360 4e-97 ref|YP_001342170.1| diguanylate cyclase [Marinomonas sp. MWYL1] ... 350 3e-94 ref|ZP_08824988.1| diguanylate cyclase [Thiorhodococcus drewsii ... 344 3e-92 ref|ZP_08506621.1| GGDEF family protein [Methyloversatilis unive... 324 3e-86 >ref|YP_972314.1| diguanylate cyclase [Acidovorax citrulli AAC00-1] gb|ABM34540.1| diguanylate cyclase [Acidovorax citrulli AAC00-1] Length = 591 Score = 431 bits (1109), Expect = e-118, Method: Compositional matrix adjust. Identities = 245/558 (43%), Positives = 340/558 (60%), Gaps = 6/558 (1%) Query: 6 LRVRHFKTQLLTFFGGL-IAFWLAVVGGYFVGEEAGA-VVNNRGEALYSTAVAASQLLSV 63 LR + QL +FG L +A L V G+++G A + G+ L++TA +A+ LL+ Sbjct: 31 LRPSSLRGQLTLWFGALTLASVLGV--GFYLGRIATQDLARFAGDLLHTTARSATDLLAT 88 Query: 64 EVEERSLEIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDG 123 + ER+LEIDLL + L + + L RK+AH+EY WIGI G+V+ AT G Sbjct: 89 NLRERALEIDLLRQLPLFTQGDLGGEAMRRALDQRKDAHSEYAWIGIASPEGRVLQATGG 148 Query: 124 ILLGEKISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAV 183 +L+GEK+ RPWF+ + GDVH+AVLLAK LP+++ +QPLRFIDFA+P+ D NG + Sbjct: 149 LLVGEKVDQRPWFRDATTRLFVGDVHDAVLLAKRLPERRLDQPLRFIDFAAPIVDANGTL 208 Query: 184 LGVLGAHASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLPDGQRPA 243 GV+GAHA W WV++ V D + +E+ I + G++LYPF G +RLPD + Sbjct: 209 RGVIGAHAHWYWVTETVEAVAVDRAAGPGIEVLIADRSGNVLYPFRLAGQSRLPDRAAAS 268 Query: 244 ERFEVSNWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVA 303 R+E WA +YL S VP+ S L W+IVVRQPA A P R LR +L +LGL A Sbjct: 269 ARYERLTWADGTEYLSSTVPLPSVAGADLGWRIVVRQPADEALAPARALRRQLALLGLAA 328 Query: 304 GLLMVMGAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDPRGAGSAELAQLCSTFHTMT 363 LL + A+ A + +P+E LA A + RR+ +PD G + E+AQL +F +MT Sbjct: 329 ALLCGLVAYRLAARFSRPLELLARAAHAIERREGVPRYPD--GTDTLEVAQLNRSFQSMT 386 Query: 364 ESLLDREQKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSAA 423 SLL+REQ+L LN SLE+QV RT L AN +L LA DPLTGL NRR F+E L A Sbjct: 387 ASLLEREQELSRLNTSLENQVRERTLALHQANQELENLAVRDPLTGLYNRRRFDEALQAY 446 Query: 424 FQQMKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARYGGE 483 + + H + +++VD D FK+VNDT GH+ GD VL+ LA +++ +R+TD +AR+GGE Sbjct: 447 TARCRELGHRFALMIVDADHFKRVNDTHGHQTGDAVLRHLAGVITGCVRSTDFIARFGGE 506 Query: 484 EFVVLLAPVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAVRRA 543 EFVVL+ E+ VA+KIR V FP V +T+S+GLA + RA Sbjct: 507 EFVVLMPEPRDREEGRFVAEKIRLAVGHTPFPGVGHLTVSIGLAFCHGGGEPLATILERA 566 Query: 544 DGALYKAKEKGRNCVITA 561 D ALY+AKE+GR+ V A Sbjct: 567 DKALYQAKEEGRDRVCVA 584 >ref|YP_004236358.1| diguanylate cyclase [Acidovorax avenae subsp. avenae ATCC 19860] gb|ADX47791.1| diguanylate cyclase [Acidovorax avenae subsp. avenae ATCC 19860] Length = 568 Score = 421 bits (1083), Expect = e-115, Method: Compositional matrix adjust. Identities = 247/558 (44%), Positives = 340/558 (60%), Gaps = 6/558 (1%) Query: 6 LRVRHFKTQLLTFFGGL-IAFWLAVVGGYFVGEEAGA-VVNNRGEALYSTAVAASQLLSV 63 LR + QL +FG L +A L V G+++G A + G+ L++TA +A+ LL+ Sbjct: 12 LRPPSLRGQLTLWFGALTLASVLGV--GFYLGRIATRDLARFAGDLLHTTARSATDLLAT 69 Query: 64 EVEERSLEIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDG 123 + ER+LEIDLL + L + + L RK+AH+EY WIGI GQV+ AT G Sbjct: 70 NLRERALEIDLLRKLPLFTQGDLGGDAMRRALDQRKDAHSEYAWIGISSPEGQVLQATGG 129 Query: 124 ILLGEKISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAV 183 IL+GEK+ RPWF+ + GDVH+AVLLAK LP+++ +QPLRFIDFA+P+ D NG + Sbjct: 130 ILVGEKVDQRPWFREASTHLFVGDVHDAVLLAKRLPERRLDQPLRFIDFAAPIVDANGTL 189 Query: 184 LGVLGAHASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLPDGQRPA 243 GV+GAHA W WV++ V D + +E+ I + G++LYPF G TRLPD P+ Sbjct: 190 RGVIGAHAHWYWVTETVEAVAVDRAAGHGIEVLIADRSGNVLYPFRLAGQTRLPDRAGPS 249 Query: 244 ERFEVSNWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVA 303 R+E WA +YL S V + S L W+IVVRQPA A P R L +L +LGL A Sbjct: 250 ARYERLTWADGTEYLSSTVALPSVAGADLGWRIVVRQPADEALAPARALGRQLALLGLAA 309 Query: 304 GLLMVMGAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDPRGAGSAELAQLCSTFHTMT 363 LL + A+ A + +P+E LA A + RR+ + +PD G + E+AQL +F +MT Sbjct: 310 ALLCGLVAYRLAARFSRPLELLARAARAIERREGEPRYPD--GTDTLEVAQLNRSFQSMT 367 Query: 364 ESLLDREQKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSAA 423 SLL+REQ+L LN SLE+QV RT L AN +L LA DPLTGL NRR F+E L A Sbjct: 368 ASLLEREQELSRLNTSLENQVRERTLALHQANQELENLAVRDPLTGLYNRRRFDEALQAY 427 Query: 424 FQQMKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARYGGE 483 + + H + +++VD D FK+VNDT GH+ GD VL+ LA +++ +R+TD VAR+GGE Sbjct: 428 SARCRELGHRFALMIVDADHFKRVNDTHGHQTGDAVLRHLAGVITGCMRSTDFVARFGGE 487 Query: 484 EFVVLLAPVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAVRRA 543 EFVVL+ E+ +VA+KIR V FP V +T+S+GLA + RA Sbjct: 488 EFVVLMPEPRDREEGRLVAEKIRLAVGHTPFPGVGHLTVSIGLAFCHGGGEPLASILERA 547 Query: 544 DGALYKAKEKGRNCVITA 561 D ALY+AK +GR+ V A Sbjct: 548 DKALYQAKGEGRDRVCVA 565 >ref|YP_349279.1| diguanylate cyclase [Pseudomonas fluorescens Pf0-1] gb|ABA75288.1| putative GGDEF domain regulatory protein [Pseudomonas fluorescens Pf0-1] Length = 559 Score = 416 bits (1070), Expect = e-114, Method: Compositional matrix adjust. Identities = 241/552 (43%), Positives = 332/552 (60%), Gaps = 15/552 (2%) Query: 11 FKTQLLTFFGGLIAFWLAVVGGYFVGEEAGAVVNN-RGEALYSTAVAASQLLSVEVEERS 69 ++ L +F GL L VG ++VG+ A + G AL STA +A+ LL ++ ER Sbjct: 6 LRSHLTLWFAGLSLLTLLSVG-FYVGDIATEQMKRASGNALLSTARSAAALLGEQLRERQ 64 Query: 70 LEIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDGILLGEK 129 LE+ LL+R+ L L +P +L+ +QLR EA EY W+G+ D +G+V A +G+L+G+ Sbjct: 65 LEVYLLSRAPHLERGDLDNPAILKSMQLRTEARTEYAWMGVTDAQGRVHQAVNGLLVGQA 124 Query: 130 ISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAVLGVLGA 189 + RPWF+AGL G Y GD HEAVLLAK LP +PLRFIDFA+P+ + +G V+GVLGA Sbjct: 125 VQQRPWFQAGLRGEYTGDPHEAVLLAKLLPGLPNGEPLRFIDFAAPIRNADGQVIGVLGA 184 Query: 190 HASWDWVSDAV-VKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLPDGQRPAERFEV 248 HA W WV+ V + ++ +E I++ G +LYP VG Q PA+ Sbjct: 185 HAHWSWVTHIVESAAMSHKGAEPDIEALIIDHDGKVLYPEALVGQ------QMPAKDPNS 238 Query: 249 SNWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVAGLLMV 308 W YL S V V + L W I VRQP A +P R L YKL++LG+ A + Sbjct: 239 PGWVVGNGYLTSEVTVPTPTGTALSWSIAVRQPLDTALQPARLLFYKLLLLGVFAAVAFG 298 Query: 309 MGAFYFARKLCKPIEALAEVAEQVLRRDRKVIFP--DPRGAGSAELAQLCSTFHTMTESL 366 + A+Y A L +PIE LA A++V FP P E+AQL + MT+SL Sbjct: 299 LVAYYLALYLSRPIEQLARSAQKVQNNQPGAHFPLRHP----VREIAQLGQSIDAMTQSL 354 Query: 367 LDREQKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSAAFQQ 426 L +E++L+E N SLE V RT L LAN +L LAT D LTG+ NRR F+E+L+ Sbjct: 355 LAKERELQETNASLEATVAQRTAALTLANAELLNLATHDGLTGVYNRRRFDEKLTEYSLL 414 Query: 427 MKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARYGGEEFV 486 +RT P+ +L++D D FK++NDT GH AGD VL++LA L+ S+R+TD VARYGGEEF Sbjct: 415 FRRTGRPFALLLIDADHFKRINDTHGHAAGDDVLRQLAQLIQISIRSTDFVARYGGEEFA 474 Query: 487 VLLAPVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAVRRADGA 546 VLL + + IVA+KIR +A+A+FP+V +T+S+G++ A D T V+RAD Sbjct: 475 VLLPEIAKPDTPDIVAEKIRSAIAEADFPAVGPVTVSIGVSLADPADNTPTTLVKRADQQ 534 Query: 547 LYKAKEKGRNCV 558 LYKAK GRN V Sbjct: 535 LYKAKAAGRNQV 546 >ref|YP_002873133.1| putative GGDEF domain signaling protein [Pseudomonas fluorescens SBW25] emb|CAY49790.1| putative GGDEF domain signaling protein [Pseudomonas fluorescens SBW25] Length = 547 Score = 399 bits (1025), Expect = e-109, Method: Compositional matrix adjust. Identities = 226/549 (41%), Positives = 325/549 (59%), Gaps = 9/549 (1%) Query: 11 FKTQLLTFFGGLIAFWLAVVGGYFVGEEAGAVVNN-RGEALYSTAVAASQLLSVEVEERS 69 ++ L +F GL L VG ++VG A V G L STA + + LL+V++ ER Sbjct: 6 LRSHLTLWFAGLSLLTLLSVG-FYVGHIATEQVKQASGNTLLSTARSTAALLAVQLRERQ 64 Query: 70 LEIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDGILLGEK 129 LE+ LL+++ L P +L +++LR ++ EY W+G+ D G+V A +G+L+ + Sbjct: 65 LEVSLLSKAPLFRQGNLDAPDILTLMELRTQSRAEYAWMGVADAEGKVHQAVNGLLVNQS 124 Query: 130 ISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAVLGVLGA 189 + RPWF+AG+ G YAGD HEAVLLAK LP +PLRFIDFA+P+ + G +GVLGA Sbjct: 125 VQQRPWFQAGMRGEYAGDPHEAVLLAKLLPGATNGEPLRFIDFAAPIRNAQGETIGVLGA 184 Query: 190 HASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLPDGQRPAERFEVS 249 HA W WV+ V + + LE IV+ G +LYP + + +P A + S Sbjct: 185 HAHWRWVTQIVDSAVMQKDALPDLEALIVDFDGKVLYP-QVLAGEPMPQ----ANLGKAS 239 Query: 250 NWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVAGLLMVM 309 W++ Y+ + V V S K+ W IVVRQP +A +P R L YKL++LG++A L+ + Sbjct: 240 GWSTGNGYVTASVAVPSPSNAKVSWYIVVRQPLDIALQPARVLLYKLLLLGVIAALVFGL 299 Query: 310 GAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDPRGAGSAELAQLCSTFHTMTESLLDR 369 A+Y A L +PIE L A+QV FP E+AQL + MT+SLL + Sbjct: 300 VAYYLASTLSRPIERLVRSAKQVQDNQPGAAFPQEHPV--LEIAQLGRSLTGMTQSLLSK 357 Query: 370 EQKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSAAFQQMKR 429 E++L++ N SLE V RT +L AN +L +LAT D LTG+ NRR F+E+L+ +R Sbjct: 358 ERQLQDANASLEATVAQRTADLTQANAELLKLATHDALTGVYNRRRFDEKLAENSLLFQR 417 Query: 430 TSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARYGGEEFVVLL 489 T + +L++D D+FK+VND++GH GD VL +LA L+ + R TD VARYGGEEF VLL Sbjct: 418 TGRTFALLLIDADYFKRVNDSYGHAIGDDVLCQLAALIKNTTRATDFVARYGGEEFAVLL 477 Query: 490 APVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAVRRADGALYK 549 V + +VA+KIR V A FP+V +T+S+G+ A +D ++RAD LY+ Sbjct: 478 PEVEEPDSPDVVAEKIRVAVEAAVFPTVGHVTVSIGVGVAEPSDRDTSALLKRADMQLYE 537 Query: 550 AKEKGRNCV 558 AK GRN V Sbjct: 538 AKAAGRNRV 546 >ref|ZP_08402673.1| putative GGDEF domain signaling protein [Rubrivivax benzoatilyticus JA2] gb|EGJ11006.1| putative GGDEF domain signaling protein [Rubrivivax benzoatilyticus JA2] Length = 562 Score = 393 bits (1010), Expect = e-107, Method: Compositional matrix adjust. Identities = 231/551 (41%), Positives = 312/551 (56%), Gaps = 3/551 (0%) Query: 11 FKTQLLTFFGGLIAFWLAVVGGYFVGEEAGAVVNNRGEALYSTAVAASQLLSVEVEERSL 70 F+ +L GGL L VG Y N G L A +A+ L+ ++ER Sbjct: 9 FRLRLTLGAGGLALCTLLGVGLYAARLATQERQNFVGLQLLGAARSAAIGLATRLQERER 68 Query: 71 EIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDGILLGEKI 130 E+++L+R +L L +V + L LRKE + EY W+G+ L G+V++AT G+L+G + Sbjct: 69 EVEILSRVPSLAESPLDSERVARSLALRKETNTEYAWMGVASLDGRVVNATGGLLVGADV 128 Query: 131 SMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAVLGVLGAH 190 RPWF AGL G+Y GDVH+A LLA L + +PLRFID A+PV G V GVL AH Sbjct: 129 RTRPWFAAGLKGSYTGDVHQAALLATLLEPRPGGEPLRFIDLAAPVIGPAGQVRGVLAAH 188 Query: 191 ASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLPDGQRPAERFEVSN 250 WDW+++AV K +R+ E+ I+ G +LYP G TRLP ERF + Sbjct: 189 VHWDWIANAVRKAVREDPRATDTEVIILGRDGTVLYPLRAPG-TRLPQAL-GRERFGMQE 246 Query: 251 WASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVAGLLMVMG 310 YL++ V L W +V+RQP+A A PV QLR +L +GL LL+ Sbjct: 247 EPGGASYLVARASVPVTQHSDLGWSVVLRQPSAAATAPVAQLRDRLFAIGLATSLLVAAL 306 Query: 311 AFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDPRGAGSAELAQLCSTFHTMTESLLDRE 370 A+ A ++ +P+E L A +R R PR GS EL+ L MTE+LLDRE Sbjct: 307 AYVLAARVSRPLERLV-TAVMSVREGRGGQANFPRDGGSPELSALSDAVREMTETLLDRE 365 Query: 371 QKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSAAFQQMKRT 430 +L + N LE V RT +L AN +LA LA +D LTGLANRR FE+R + + +R+ Sbjct: 366 ARLAQANAHLEQTVAERTCQLSQANEELARLAAQDALTGLANRRAFEQRAAEEEARCRRS 425 Query: 431 SHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARYGGEEFVVLLA 490 +G+L++D+D FK VND FGH GD+VLQ++A LL + R TDLVAR GGEEF VLL Sbjct: 426 GTGFGLLLLDIDHFKDVNDRFGHATGDQVLQQIARLLESATRETDLVARLGGEEFAVLLP 485 Query: 491 PVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAVRRADGALYKA 550 + VA+KIR+ + A F V +T+SVG A ND A+RRAD ALYKA Sbjct: 486 ELGESADTLRVAEKIRQAIQAAHFGPVGEVTVSVGCAKGDGNDTPVQLALRRADEALYKA 545 Query: 551 KEKGRNCVITA 561 K+ GRN + A Sbjct: 546 KQAGRNRCVAA 556 >ref|NP_903805.1| hypothetical protein CV_4135 [Chromobacterium violaceum ATCC 12472] gb|AAQ61796.1| conserved hypothetical protein [Chromobacterium violaceum ATCC 12472] Length = 585 Score = 370 bits (949), Expect = e-100, Method: Compositional matrix adjust. Identities = 228/561 (40%), Positives = 328/561 (58%), Gaps = 21/561 (3%) Query: 11 FKTQLLTFFGGLIAFWLAVVGGYFVGEEAGAVVNNRGEALYSTAVAASQLLSVEVEERSL 70 F+ +L FGGL + + +V ++GEA+ S A ++ + + ER Sbjct: 32 FRLRLAILFGGLFLASALLAAACLDQVLSDRIVRDQGEAMNSLAANIAKAIESNLRERHR 91 Query: 71 EIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDGILLGEKI 130 E+ LLA++ T V L V Q L+ K+A+ Y WIGI D G+++ A G+L+G+ Sbjct: 92 EVLLLAQTPTYVRVPLDGDDVRQSLERTKQAYKYYAWIGITDAEGKIVSAAGGMLVGQSA 151 Query: 131 SMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPN-QPLRFIDFASPVYDRNGAVLGVLGA 189 + RPWF G + GD+H+AVLLAK LP + P +PLRF+DFASPVYD +G + GVL Sbjct: 152 AKRPWFIHGRHAPFVGDIHQAVLLAKLLPNRSPQGEPLRFVDFASPVYDPSGKLRGVLAT 211 Query: 190 HASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLPDGQRPAERFEVS 249 HA WDWV D + +++ + LE FIV+ + ++L PFE VG + P + F + Sbjct: 212 HALWDWVEDIIRERL---PARSGLETFIVDRQNNLLSPFEAVGRMQAPAPMPSGQTFRLG 268 Query: 250 NWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVAGLLMVM 309 W G YL S V+ A LDW++V+RQP A + +LR L++LGL A L++ Sbjct: 269 PWPGGGNYLYSESRVREA---GLDWRVVIRQPRQQALTALNRLRGALMLLGLAASALLMA 325 Query: 310 GAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPD--PRGAGSAELAQLCSTFHTMTESLL 367 + A +P+E LA VAE+V R D + PD RG G+ EL QL MT +LL Sbjct: 326 AVYRLAASFSRPLEQLAGVAERVGRGDEQ---PDWEIRG-GTQELRQLSDAMRNMTATLL 381 Query: 368 DREQKLRELNESLEHQVDVRTNELKLAN-------LKLAELATEDPLTGLANRRYFEERL 420 RE++L ++N +LE V RT +L+ +N +LA+LA D LTGL NR E+L Sbjct: 382 ARERQLADVNANLEQMVADRTEQLRESNRLLVQKAAQLAQLARNDALTGLHNRMAANEQL 441 Query: 421 SAAFQQMKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARY 480 + R+ PY VL++DVD FK+VNDT GH+AGD+VL+ +A +L + R TD VAR+ Sbjct: 442 QEEHLRHGRSGAPYAVLLLDVDHFKRVNDTHGHDAGDRVLRHIADILRRAARATDFVARF 501 Query: 481 GGEEFVVLLAPVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAV 540 GGEEF++LL P T + A ++A+KIR V +++ P V +T+S+GLA D + AV Sbjct: 502 GGEEFLLLL-PETDADGAAVLAEKIRASVEQSQAPDVGRVTLSIGLATVVPADSQPEMAV 560 Query: 541 RRADGALYKAKEKGRNCVITA 561 +RAD ALY+AK GRN V A Sbjct: 561 KRADQALYRAKAAGRNRVEAA 581 >ref|YP_001099097.1| hypothetical protein HEAR0777 [Herminiimonas arsenicoxydans] emb|CAL60970.1| conserved hypothetical protein [Herminiimonas arsenicoxydans] Length = 568 Score = 360 bits (924), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 205/558 (36%), Positives = 323/558 (57%), Gaps = 12/558 (2%) Query: 9 RHFKTQLLTFFGGLIAFWLAVVGGYFVGEEAGA-VVNNRGEALYSTAVAASQLLSVEVEE 67 R F+ Q+ FG +I+ ++++ +++ + A ++ + E L AA+ +L+ + E Sbjct: 8 RTFRVQMALLFG-VISLFISLPAYFYISNQHKAQLIEYKRETLKGVTNAAATILTESLAE 66 Query: 68 RSLEIDLLARSLTL-VSD-RLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDGIL 125 R EI LL ++ + SD R+AD V L+ K+++ Y WIGI + G V AT L Sbjct: 67 RHREIVLLTQTPSYQKSDFRMAD--VRASLERVKQSYAHYSWIGIANAEGLVQSATSSHL 124 Query: 126 LGEKISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAVLG 185 G +S RPWF+ GL G + GD+HEA+LLAK LP PNQP+RFIDF++P++D +G V G Sbjct: 125 EGADVSKRPWFQEGLKGPFVGDLHEALLLAKLLPNPSPNQPIRFIDFSAPIFDASGRVKG 184 Query: 186 VLGAHASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDILYPFEKVGATRLP--DGQRPA 243 VL AHA W W V +++FI+N KG+++YP + R+P D + Sbjct: 185 VLAAHAHWQWAGSLVGTMAPIHAQRDGIDLFILNHKGEVIYPEKIPEKLRVPSLDTLSNS 244 Query: 244 ERFEVSNWASEGQYLMSVVPVKSAMQLK-LDWKIVVRQPAALAFEPVRQLRYKLIVLGLV 302 + +W + YL + VK+ +K L W++VVRQ V+ L + L Sbjct: 245 ADKKFVSWGEDKLYLTTSAAVKTPASVKSLGWQVVVRQVDTSVLTEVKNLERVNLFTMLT 304 Query: 303 AGLLMVMGAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDPRGAGSAELAQLCSTFHTM 362 + + + A+ A ++ +P+E L A ++ +++V F + A EL +L M Sbjct: 305 SSIAFLFLAWIVANRISRPVEDLTRTARRIESGEKEVGFAEKFWA--RELQRLSDALRGM 362 Query: 363 TESLLDREQKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSA 422 + +L+ + + L + N+ LE +V RT EL+ N+ L +LA D LTGLANR + ERL+ Sbjct: 363 SNTLIQQREALAQSNQELEAKVSARTAELQELNITLEQLARTDALTGLANRMHTNERLAE 422 Query: 423 AFQQMKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESLRNTDLVARYGG 482 F + KR+ PY +LM+DVDFFK+VND +GH GD+VL+ +A +LS ++R TD V R+GG Sbjct: 423 EFARFKRSKIPYCILMLDVDFFKRVNDIYGHGVGDEVLKHVASILSATVRKTDFVGRHGG 482 Query: 483 EEFVVLLAPVTSEEQAFIVADKIREIVAKAEFPSVKSITISVGLAAASINDPTQDDAVRR 542 EEF+ +L P+T A +VA+KIR + V ++T+S+G+ ++ND +D AV R Sbjct: 483 EEFLSIL-PMTDSSAAMVVAEKIRNTIESTPIGPVGNLTVSIGVQEVTVNDINEDVAVTR 541 Query: 543 ADGALYKAKEKGRNCVIT 560 AD +Y+AK+ GRN VI+ Sbjct: 542 ADECMYQAKKSGRNKVIS 559 >ref|YP_001342170.1| diguanylate cyclase [Marinomonas sp. MWYL1] gb|ABR72235.1| diguanylate cyclase [Marinomonas sp. MWYL1] Length = 556 Score = 350 bits (899), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 193/515 (37%), Positives = 304/515 (59%), Gaps = 7/515 (1%) Query: 47 GEALYSTAVAASQLLSVEVEERSLEIDLLARSLTLVSDRLADPKVLQM-LQLRKEAHNEY 105 GE+L + + + S +LS + ER E+ LL++ +L + D LQ + K ++ +Y Sbjct: 44 GESLVNLSQSISNMLSANLMEREREVVLLSKRTSLYETQ--DLSGLQYAIDQIKSSYKDY 101 Query: 106 LWIGIGDLRGQVIHATDGILLGEKISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQ 165 WIG ++ G V+ +++G+L +S RPWF +G +G + G+VH+A+LL LP+ K Sbjct: 102 AWIGFANIDGVVLASSNGVLKEADVSQRPWFISGRSGPFIGNVHKALLLENLLPKTKDGS 161 Query: 166 PLRFIDFASPVYDRNGAVLGVLGAHASWDWVSDAVVKKIRDPQSDQQLEIFIVNSKGDIL 225 P+RF+DFA+PV +G + GV+ HA W WV + ++ + D + ++IFI++++ +L Sbjct: 162 PIRFVDFAAPVIGESGELKGVVATHADWAWVKEVLLSSLTDTSKRKNIDIFIIDNEHRVL 221 Query: 226 YP-FEKVGATRLPDGQRPAERFEVSNWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAAL 284 YP + +P +F+ W + +YL S+V V+S L W+IVVRQP ++ Sbjct: 222 YPDYHFPNDIEVPKTLPKDGQFKSLLWQDDKEYLTSLVSVRSPESTDLAWQIVVRQPLSI 281 Query: 285 AFEPVRQLRYKLIVLGLVAGLLMVMGAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDP 344 A V ++ L+ G+ A LL ++ A+ FA L +P+E LA A+ + + DRKV F Sbjct: 282 AMSAVNEVHKLLLFFGVFATLLCMLLAYQFAGTLSRPLERLALTAKSIQQGDRKVTFQS- 340 Query: 345 RGAGSAELAQLCSTFHTMTESLLDREQKLRELNESLEHQVDVRTNELKLANLKLAELATE 404 + E+A L + M SLL REQ L ++N LE +V RT EL+ +N L +A + Sbjct: 341 -DSKLIEVASLSRSLQEMMSSLLTREQSLMQMNVMLETKVKNRTAELEASNRSLEAIARK 399 Query: 405 DPLTGLANRRYFEERLSAAFQQMKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLA 464 DPLT + NR +E L ++Q + + P+ V+M+D D FK+VND+FGH GD VLQK+A Sbjct: 400 DPLTHIYNRLALDEALHKEYRQAQESKCPFAVIMIDADHFKRVNDSFGHTVGDLVLQKIA 459 Query: 465 VLLSESLRNTDLVARYGGEEFVVLLAPVTSEEQAFIVADKIREIVAKAEFPSVKSITISV 524 LL+ + + +VAR+GGEEF VLL P + ++A +A+ IRE + K E +T S Sbjct: 460 KLLTVQVGDKGIVARFGGEEFTVLL-PNMNADEAKNIAEMIREALEKEEMSDGLYVTASF 518 Query: 525 GLAAASINDPTQDDAVRRADGALYKAKEKGRNCVI 559 G+A I+D + + RAD ALYKAKE+GRN V+ Sbjct: 519 GVAMYEIDDSHYEQVLNRADAALYKAKEQGRNRVV 553 >ref|ZP_08824988.1| diguanylate cyclase [Thiorhodococcus drewsii AZ1] gb|EGV28437.1| diguanylate cyclase [Thiorhodococcus drewsii AZ1] Length = 593 Score = 344 bits (882), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 205/554 (37%), Positives = 315/554 (56%), Gaps = 13/554 (2%) Query: 11 FKTQLLTFFGGLIAFWLAVVGGYFVGEEAGAVVNNRGEALYSTAVAASQLLSVEVEERSL 70 + +L FGG+ G A +++ GE + + + +S + ER Sbjct: 23 IRFRLTLMFGGVSLILGITSTGLIEHLAARSMIALSGERTREISRSIANSISQSLIERLR 82 Query: 71 EIDLLARSLTLVSDRLADPKVLQMLQLRKEAHNEYLWIGIGDLRGQVIHATDGILLGEKI 130 EI L++RS L S +P V +++ KE++ Y W+G+ D G+V+ AT +L G+ + Sbjct: 83 EITLMSRSPLLTSGDWTNPAVRTIIEAAKESYTPYAWMGVADTSGRVVIATGHLLEGKDV 142 Query: 131 SMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQKPNQPLRFIDFASPVYDRNGAVLGVLGAH 190 S RPWF G G + GDVH+A+LL +L P+ PLRFIDFA+P+ D G LG++ H Sbjct: 143 SQRPWFVHGRTGPFLGDVHQALLLEHYLQNADPDVPLRFIDFAAPIRDPEGQWLGIVATH 202 Query: 191 ASWDWVSDAVVKKIRDPQSD-QQLEIFIVNSKGDILYPFEKVGATRLPDGQRPAERFEVS 249 A+W+WV DAV+ + P++ Q +E+ +V+ +G +LYP + G + P + + Sbjct: 203 ANWNWV-DAVISEGMSPENTAQDIEVLLVDQEGYVLYPIQGDGQLHSLGQRLPKSGYAIL 261 Query: 250 NWASEGQYLMSVVPVKSAMQLKLDWKIVVRQPAALAFEPVRQLRYKLIVLGLVAGLLMVM 309 +W + +YL + V++ L W IVVRQP +A V LRY +++LG+ LL+V Sbjct: 262 DWDNR-RYLTAQTIVRAPGTDTLSWHIVVRQPVEVALGSVADLRYHMLLLGVFMSLLLVF 320 Query: 310 GAFYFARKLCKPIEALAEVAEQVLRRDRKVIFPDPRGAGSAELAQLCSTFHTMTESLLDR 369 A A +P++ LA+VA ++ + F R EL +L S+ MT +L +R Sbjct: 321 LANRVAISFSQPLQKLAQVAYRIDHGEETFNF-TVRPFKLRELNELVSSIRGMTATLFER 379 Query: 370 EQKLRELNESLEHQVDVRTNELKLANLKLAELATEDPLTGLANRRYFEERLSAAFQQMKR 429 + L ++N SLE ++ RT +L+ ANL+LA LAT D LTG+ANRR F+E L +++ KR Sbjct: 380 KHALEQVNRSLEDRIRERTAQLREANLQLAALATTDGLTGVANRRRFDEILEQEWERAKR 439 Query: 430 TSHPYGVLMVDVDFFKKVNDTFGHEAGDKVLQKLAVLLSESL-RNTDLVARYGGEEFVVL 488 P +LM+D+DFFK+ ND +GH+ GD L+++ L+ +S+ R D VARYGGEEF + Sbjct: 440 AGTPLSLLMIDIDFFKQYNDHYGHQTGDTCLREVGRLVRDSIHRAGDAVARYGGEEFAAV 499 Query: 489 LAPVTSEEQAFIVADKIREIVAKAEFPSVKS----ITISVGLAAASINDPTQDDA--VRR 542 L P T EE A A + + + P +S +T SVG AA+ I PT+D + + R Sbjct: 500 L-PGTPEEGALSFARALCQSMHARALPHARSPVGVLTFSVG-AASMIPKPTEDASLLIAR 557 Query: 543 ADGALYKAKEKGRN 556 AD ALY+AK GRN Sbjct: 558 ADQALYQAKRNGRN 571 >ref|ZP_08506621.1| GGDEF family protein [Methyloversatilis universalis FAM5] gb|EGK69748.1| GGDEF family protein [Methyloversatilis universalis FAM5] Length = 558 Score = 324 bits (830), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 191/520 (36%), Positives = 302/520 (58%), Gaps = 7/520 (1%) Query: 42 VVNNRGEALYSTAVAASQLLSVEVEERSLEIDLLARSLTLVSDRLADPKVLQMLQLRKEA 101 ++ +RGEAL+ AVA + +++ + ER E++LLAR+ L + L+ +++ Sbjct: 39 LLEDRGEALHEQAVAVAAVIAENLNERRREVELLARTPLFRKAPLDSVEFQPSLERLQKS 98 Query: 102 HNEYLWIGIGDLRGQVIHATDGILLGEKISMRPWFKAGLAGAYAGDVHEAVLLAKHLPQQ 161 + Y WIG+ D+ G V +T G+L+G +S RPWF G G + GDVH+A+LL++ L + Sbjct: 99 YPAYSWIGLTDVDGVVRASTGGLLMGADVSQRPWFTGGQKGPHLGDVHDALLLSRLLRPE 158 Query: 162 KPNQPLRFIDFASPVYDRNGAVLGVLGAHASWDWVSDAVVKKIRDPQSDQ-QLEIFIVNS 220 P+RFIDF+ PV+D +G + GVLGAHA W W + V++ ++ +D+ LE IVN Sbjct: 159 PDGAPIRFIDFSVPVFDDSGRLRGVLGAHAHWRWAGE-VLQVLKSRDTDRGGLEYLIVNR 217 Query: 221 KGDILYPFEKVGATRLPDGQRPAERFEVSNWASEGQYLMSVVPVKSAM-QLKLDWKIVVR 279 +G +++P L + R + + W + +Y+ ++ PV+ + + L W++VVR Sbjct: 218 QGRVIHPERDAMPLSLAERLR-TQPVVIDRWGGQTEYVTTLAPVRDIVPEAPLGWQVVVR 276 Query: 280 QPAALAFEPVRQLRYKLIVLGLVAGLLMVMGAFYFARKLCKPIEALAEVAEQVLRRDRKV 339 QP V +LR+ +++ L+AGL + + A++ A +L P+E LA A ++ + D Sbjct: 277 QPLHTVIADVAELRHAVLLFSLMAGLTLCLLAWWAAGRLSTPLEHLALQARRIEQGDESA 336 Query: 340 IFPDPRGAGSAELAQLCSTFHTMTESLLDREQKLRELNESLEHQVDVRTNELKLANLKLA 399 + E+ L +M +L+ R + L N +LE +V+ RT EL N +L Sbjct: 337 ELAIT--GSTREVVHLGEALRSMAATLIHRREALEASNHALEARVEERTAELARLNDELR 394 Query: 400 ELATEDPLTGLANRRYFEERLSAAFQQMKRTSHPYGVLMVDVDFFKKVNDTFGHEAGDKV 459 E A D LTGL NR ERL F +MKR Y VL++D+D+FK++NDT GH AGD V Sbjct: 395 EQARRDVLTGLPNRLAANERLREEFVRMKRMRTAYAVLVLDIDYFKRINDTHGHPAGDAV 454 Query: 460 LQKLAVLLSESLRNTDLVARYGGEEFVVLLAPVTSEEQAFIVADKIREIVAKAEFPSVKS 519 L+ ++ +L +LR +D VAR+GGEEF++LL P T A V +K+R V + +V + Sbjct: 455 LRHVSGVLRGALRESDFVARFGGEEFLILL-PATPLNDAVAVGEKVRCAVESSPTAAVGA 513 Query: 520 ITISVGLAAASINDPTQDDAVRRADGALYKAKEKGRNCVI 559 +T+S+GLA A +D AVR AD LY+AK GRN +I Sbjct: 514 VTLSIGLAMADPTHQDEDVAVRAADALLYQAKSAGRNRLI 553