BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0293.p (304 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774656.1| regulator of the two-component system protei... 499 e-139 ref|YP_003775687.1| two component response regulator protein [He... 223 3e-56 ref|YP_002890202.1| response regulator receiver modulated diguan... 159 4e-37 ref|YP_315781.1| response regulator receiver modulated diguanyla... 154 2e-35 ref|YP_003167130.1| response regulator receiver modulated diguan... 153 3e-35 ref|YP_003845931.1| response regulator receiver modulated diguan... 150 3e-34 ref|YP_003846773.1| response regulator receiver modulated diguan... 149 5e-34 ref|YP_003165410.1| response regulator receiver modulated diguan... 147 2e-33 ref|ZP_08505536.1| Putative response regulator [Methyloversatili... 146 3e-33 ref|YP_004696329.1| response regulator receiver modulated diguan... 144 1e-32 >ref|YP_003774656.1| regulator of the two-component system protein [Herbaspirillum seropedicae SmR1] gb|ADJ62748.1| regulator of the two-component system protein [Herbaspirillum seropedicae SmR1] Length = 317 Score = 499 bits (1285), Expect = e-139, Method: Compositional matrix adjust. Identities = 250/255 (98%), Positives = 251/255 (98%) Query: 1 MLTFIEPTLFDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRI 60 MLTFIEPTLFDKLRSAQALPSPGGVRLTIM+LCAQDNPDMAELIHLVQADPALSGRIIRI Sbjct: 1 MLTFIEPTLFDKLRSAQALPSPGGVRLTIMRLCAQDNPDMAELIHLVQADPALSGRIIRI 60 Query: 61 VNVLNAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFA 120 VNVLNAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFA Sbjct: 61 VNVLNAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFA 120 Query: 121 MACSAQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPARLAMEQ 180 MACSAQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPAR AMEQ Sbjct: 121 MACSAQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPARRAMEQ 180 Query: 181 SLFGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAE 240 SLFGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAE Sbjct: 181 SLFGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAE 240 Query: 241 LGCGPAQQAQAGACR 255 LGCGPAQQAQA R Sbjct: 241 LGCGPAQQAQAALAR 255 >ref|YP_003775687.1| two component response regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ63779.1| two component response regulator protein [Herbaspirillum seropedicae SmR1] Length = 310 Score = 223 bits (568), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 116/242 (47%), Positives = 162/242 (66%), Gaps = 2/242 (0%) Query: 1 MLTFIEPTLFDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRI 60 M T+++P F +++ ++ LP+P GVRL IMQ+C Q++ + EL+ VQ DP L+GR+I+I Sbjct: 1 MSTYVDPQTFREMQDSEVLPAPSGVRLKIMQMCQQEDIALPELVAQVQGDPVLAGRLIQI 60 Query: 61 VNVLNAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFA 120 N+ N + R +ASV+++ LL+VGL AVRQ+ALA+SL E+ CA F AFW+ S A Sbjct: 61 ANIPNINKGRMVASVNVELLLMVGLHAVRQMALAISLTESARRGDCAEFDYDAFWSRSTA 120 Query: 121 MACSAQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALL-TRALDAPARLAME 179 MAC+ QA+ L+VAP EMFT GLLA IG+L LASA+P Y LL A DA R+ E Sbjct: 121 MACAGQALGDLLQVAPPAEMFTIGLLAGIGQLGLASARPKRYGELLLAGAKDAQLRV-QE 179 Query: 180 QSLFGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMA 239 + FGF+HL +AAA+MQDW P +FC+AVLH+ P G RQ ++ L LA +A Sbjct: 180 RESFGFDHLALAAAMMQDWHFPRIFCEAVLHHRDPAASGLEEDDRQQKVTRLLELAGCVA 239 Query: 240 EL 241 ++ Sbjct: 240 DV 241 >ref|YP_002890202.1| response regulator receiver modulated diguanylate cyclase [Thauera sp. MZ1T] gb|ACR01825.1| response regulator receiver modulated diguanylate cyclase [Thauera sp. MZ1T] Length = 642 Score = 159 bits (403), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 93/246 (37%), Positives = 140/246 (56%), Gaps = 3/246 (1%) Query: 5 IEPTLFDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRIVNVL 64 I+ + +L++A LPSP GV L I++L + +AEL +++ DPA GR+I+ N L Sbjct: 5 IDMKRYAQLKAAGDLPSPRGVALAIIRLTQAPDVSLAELGRVIKGDPAFVGRLIKAANGL 64 Query: 65 NAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFAMACS 124 A+ R I SV ++L+++GL AVR LAL SL T +C F P FW+ + MA S Sbjct: 65 IAENRRAIVSVQ-EALMVLGLPAVRTLALGFSLLSTYRKGTCQGFDYPRFWSSALLMAIS 123 Query: 125 AQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPA--RLAMEQSL 182 QA+T ++RV E F+ GLLA +G+L+LA+ P +S LL PA ++ +E Sbjct: 124 MQALTQRVRVVAPDEAFSLGLLARVGELSLATLYPEAFSRLLAELKRDPALQQVVLEDQA 183 Query: 183 FGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAELG 242 F NH + AA++ DW +PD V +E P + G +R+ IV L LA+A+A+L Sbjct: 184 FAMNHRELGAAMLADWGVPDALVQPVRFHEQPELAGYAEDSREAGIVQCLVLARAVAQLC 243 Query: 243 CGPAQQ 248 P + Sbjct: 244 LAPDSE 249 >ref|YP_315781.1| response regulator receiver modulated diguanylate cyclase [Thiobacillus denitrificans ATCC 25259] gb|AAZ97976.1| Putative diguanylate cyclase (GGDEF domain) [Thiobacillus denitrificans ATCC 25259] Length = 632 Score = 154 bits (388), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 85/242 (35%), Positives = 139/242 (57%), Gaps = 6/242 (2%) Query: 8 TLFDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRIVNVLNAQ 67 T D+L+ + LPSP GV L +++L +DN + E+ +VQ DPALSGR+I++ N +A Sbjct: 2 TQLDQLKLSGQLPSPRGVALAVLELSRRDNATLGEIARVVQTDPALSGRLIKLAN--SAS 59 Query: 68 RV-RPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFAMACSAQ 126 + RP+ SV ++++ G+ VRQLAL SL + +C F +W+HS MA S Q Sbjct: 60 HIARPVVSVQ-EAVVRQGMSTVRQLALGFSLLDQFRNGACTAFDYQEYWSHSLLMALSLQ 118 Query: 127 AVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPAR--LAMEQSLFG 184 A+ +++ VA E+F GLLA +G+L LA+A P Y A+L P++ + +E+S Sbjct: 119 ALGARVHVAAADELFICGLLAQVGRLALATAYPAEYDAVLHAHRTDPSKSLITLERSRLE 178 Query: 185 FNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAELGCG 244 +H+ + +M DW +P +F + HY+ P +R + ++ L L+ +A+L G Sbjct: 179 IDHIELGIVMMTDWGMPRVFTIPLAHYQDPEYTSFPHDSRANSLMLMLRLSHRLADLALG 238 Query: 245 PA 246 A Sbjct: 239 SA 240 >ref|YP_003167130.1| response regulator receiver modulated diguanylate cyclase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gb|ACV35201.1| response regulator receiver modulated diguanylate cyclase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length = 639 Score = 153 bits (387), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 79/242 (32%), Positives = 141/242 (58%), Gaps = 3/242 (1%) Query: 1 MLTFIEPTLFDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRI 60 M++F++P +D L++ LPSP GV +I++L +D+ + +L+ LVQ+DPA++GR+++ Sbjct: 1 MISFVDPDRYDTLKATGKLPSPKGVAFSIIKLLQRDDFRVPDLVQLVQSDPAIAGRLLKF 60 Query: 61 VNVLNAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFA 120 N R RPI S+ +++ +G VR L ++ S+ + CA F AFW HS A Sbjct: 61 ANAAAFGRTRPIVSLQR-AIVALGAFRVRDLVISFSVMHSHTSGQCAAFDYAAFWGHSLA 119 Query: 121 MACSAQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPARLA-ME 179 + Q + +++ E+FT GLLA +G+L +AS P Y+ +L +A A + LA +E Sbjct: 120 TGIACQELAHFAQISS-EEIFTIGLLARVGELAMASLYPDEYATVLLKAQGAQSELASLE 178 Query: 180 QSLFGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMA 239 + F +HL + A ++ +W +P++ A H+E P V +R + +L+ A+++A Sbjct: 179 RERFAMDHLQLGATMLAEWGMPEILIRAAYHHEEPDVADFADGSRLQTLTHSLNFARSLA 238 Query: 240 EL 241 E+ Sbjct: 239 EV 240 >ref|YP_003845931.1| response regulator receiver modulated diguanylate cyclase [Gallionella capsiferriformans ES-2] gb|ADL54167.1| response regulator receiver modulated diguanylate cyclase [Gallionella capsiferriformans ES-2] Length = 632 Score = 150 bits (379), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 82/223 (36%), Positives = 130/223 (58%), Gaps = 9/223 (4%) Query: 10 FDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRIVNVLNAQRV 69 F+ ++ +LPSP GV L I+QL +D+ + ++ L+ +DPAL+G I+++ N+L + Sbjct: 9 FEAFKAHGSLPSPRGVALQIIQLADRDDTTIGQIARLIGSDPALAGNIVKVANLLTHRGS 68 Query: 70 RPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFAMACSAQAVT 129 RPIASV+ D++ + G+++VRQLAL+LSL + +CA F FWAHS +AQ + Sbjct: 69 RPIASVA-DAVTIQGIKSVRQLALSLSLVDAHRHGACAGFDYQKFWAHSVCTGIAAQQIV 127 Query: 130 SQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPARLAMEQSLFGFNHLN 189 ++++V E F GLL+ IG+L LA+ P Y+ +LT A E + FG +H Sbjct: 128 AKMQVGVADEAFLLGLLSKIGRLALATVFPAEYARVLT----ADNLTEAEHAAFGIDHNQ 183 Query: 190 IAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTL 232 I A ++ DW +P LF + L+ E P E + + E W L Sbjct: 184 ITAGMLADWGMPKLFQEISLYIERP----EASEFHEGERNWRL 222 >ref|YP_003846773.1| response regulator receiver modulated diguanylate cyclase [Gallionella capsiferriformans ES-2] gb|ADL55009.1| response regulator receiver modulated diguanylate cyclase [Gallionella capsiferriformans ES-2] Length = 635 Score = 149 bits (376), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 89/227 (39%), Positives = 129/227 (56%), Gaps = 9/227 (3%) Query: 10 FDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRIVNVLNAQRV 69 F L++ LPSP GV L I+QL ++N ++ L+ +DPAL+GRII++ N+L + Sbjct: 9 FADLKANGNLPSPRGVALQIIQLADKENTTTQQIARLISSDPALAGRIIKVANLLVHREG 68 Query: 70 RPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFAMACSAQAVT 129 RPIAS+ MD++ + G+++VRQLAL+LSL +C F FWAHS +AQ + Sbjct: 69 RPIASI-MDAVTVQGIKSVRQLALSLSLVADFRSGACCGFDYQKFWAHSVCTGIAAQQIA 127 Query: 130 SQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRA-LDAPARLAMEQSLFGFNHL 188 +++ V E F GLL+ IG+L L++ YS +L A D + L E + FG NH Sbjct: 128 AKMHVGVADEAFLLGLLSQIGRLALSTLFAEEYSQVLEHATTDNLSEL--ESNAFGINHN 185 Query: 189 NIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWT-LHL 234 I A ++ DW +P LF D LH E P E + + E W LHL Sbjct: 186 QITALMLSDWGMPALFQDIALHIEQP----ESSEFHEGERNWRLLHL 228 >ref|YP_003165410.1| response regulator receiver modulated diguanylate cyclase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gb|ACV33481.1| response regulator receiver modulated diguanylate cyclase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length = 632 Score = 147 bits (371), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 82/233 (35%), Positives = 130/233 (55%), Gaps = 3/233 (1%) Query: 10 FDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRIVNVLNAQRV 69 ++LR + LPSP GV L IM++ ++ + E+ +VQ+DPALS R++R+ N A R Sbjct: 4 IEQLRLSGRLPSPKGVALAIMEITRREETTLDEVARVVQSDPALSSRLLRLSNA--AARG 61 Query: 70 RPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFAMACSAQAVT 129 RP+ S+S ++++ +G+ VR+LA+A SL + C +F P FW+HS MA ++Q + Sbjct: 62 RPVVSIS-EAVMRLGMATVRRLAMAFSLVDQYLEGPCPSFDYPGFWSHSLFMAVASQELG 120 Query: 130 SQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPARLAMEQSLFGFNHLN 189 L A E+F GLLA +G L L + P Y+ LLT + A + +E+ G +H Sbjct: 121 RLLPAASPDELFACGLLAQVGSLALVTVYPADYARLLTESCHGVALMELERRRLGVDHSE 180 Query: 190 IAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAELG 242 A+M D IP + V ++E P G +R ++V A+ MA+LG Sbjct: 181 FTVAIMADCGIPKALTEPVYYHEVPETSGFAEGSRPYQLVNLFFQARRMADLG 233 >ref|ZP_08505536.1| Putative response regulator [Methyloversatilis universalis FAM5] gb|EGK71212.1| Putative response regulator [Methyloversatilis universalis FAM5] Length = 642 Score = 146 bits (369), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 89/244 (36%), Positives = 136/244 (55%), Gaps = 3/244 (1%) Query: 1 MLTFIEPTLFDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRI 60 M I+ F+++++A LPSP G+ L+I ++ + + +AEL LVQ DPAL GR++R Sbjct: 1 MNDLIDTRRFEEIKAAGELPSPKGIALSIARMSQRGDASLAELARLVQGDPALVGRLVRA 60 Query: 61 VNVLNAQRVRPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFA 120 N A RP+ ++ D+L ++G+ AVR LAL SL + C +F FW S Sbjct: 61 ANGSLASGARPVVALR-DALAVLGMAAVRNLALGFSLISSSGEGLCRSFPYARFWTGSVI 119 Query: 121 MACSAQAVTSQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAP-ARLAME 179 A + Q + +LR A + E F+ GLLA IG L LAS P YS +L A P A L +E Sbjct: 120 RAIAMQKILMRLRTAGVEESFSVGLLAGIGALGLASVFPAQYSRVLDEARGDPVALLDLE 179 Query: 180 QSLFGFNHLNIAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMA 239 + F +H+ ++AA++ DW +P F AVL +E + + +R+ + L LA+A+ Sbjct: 180 RQAFAMSHVELSAAMLADWGMPRFFVAAVLRHEGALTLPAEDGSREYGLTLALGLARAI- 238 Query: 240 ELGC 243 E C Sbjct: 239 ETAC 242 >ref|YP_004696329.1| response regulator receiver modulated diguanylate cyclase [Nitrosomonas sp. Is79A3] gb|AEJ02930.1| response regulator receiver modulated diguanylate cyclase [Nitrosomonas sp. Is79A3] Length = 645 Score = 144 bits (364), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 79/233 (33%), Positives = 130/233 (55%), Gaps = 2/233 (0%) Query: 10 FDKLRSAQALPSPGGVRLTIMQLCAQDNPDMAELIHLVQADPALSGRIIRIVNVLNAQRV 69 D+L+ LPSP GV L +++ C +++ + E+ L+Q DPALSGR+I+ N N QR Sbjct: 6 IDQLKIGTLLPSPKGVALALLEACQREDVTINEITKLIQTDPALSGRLIQRANATN-QRS 64 Query: 70 RPIASVSMDSLLLVGLQAVRQLALALSLAETRAPASCANFSLPAFWAHSFAMACSAQAVT 129 R I+SV +++ VGL V+QLA+ SL + +C F+ FW+HS MA + Q + Sbjct: 65 RAISSV-FEAVPHVGLTVVKQLAMGFSLIDQYQEGACKGFNYQEFWSHSLLMAIAMQELG 123 Query: 130 SQLRVAPLGEMFTTGLLANIGKLTLASAQPTGYSALLTRALDAPARLAMEQSLFGFNHLN 189 RV+ E+F GL+ IG L LA+ P Y+ L+ + +EQ +H Sbjct: 124 KTTRVSAPDELFACGLMMRIGCLALATIYPDKYTELIAKQSPGITLNELEQQYLQTDHNE 183 Query: 190 IAAALMQDWKIPDLFCDAVLHYETPVVIGEIAATRQDEIVWTLHLAQAMAELG 242 + AA++ ++ +P +F + + ++E P G +R +IV L+LA+ +A+ G Sbjct: 184 LTAAMLINFGVPRIFVEPIYYHEIPTESGFSEGSRPYQIVHLLYLAKQIADFG 236