BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0165.p (448 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775529.1| signal transduction containing EAL and modif... 916 0.0 ref|YP_001353014.1| signal transduction protein [Janthinobacteri... 472 e-131 ref|YP_001100394.1| EAL domain-containing protein [Herminiimonas... 464 e-128 ref|YP_412027.1| diguanylate phosphodiesterase [Nitrosospira mul... 421 e-115 ref|XP_002539661.1| conserved hypothetical protein [Ricinus comm... 306 6e-81 ref|YP_286500.1| EAL [Dechloromonas aromatica RCB] >gi|71848534|... 302 8e-80 ref|YP_004294711.1| diguanylate phosphodiesterase metal dependen... 293 3e-77 ref|YP_001231726.1| diguanylate phosphodiesterase [Geobacter ura... 293 5e-77 ref|YP_004694045.1| diguanylate phosphodiesterase with metal dep... 290 3e-76 ref|YP_004694190.1| diguanylate phosphodiesterase with metal dep... 286 4e-75 >ref|YP_003775529.1| signal transduction containing EAL and modified HD-GYP domains protein [Herbaspirillum seropedicae SmR1] gb|ADJ63621.1| signal transduction containing EAL and modified HD-GYP domains protein [Herbaspirillum seropedicae SmR1] Length = 448 Score = 916 bits (2367), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/448 (100%), Positives = 448/448 (100%) Query: 1 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI 60 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI Sbjct: 1 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI 60 Query: 61 AHASELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVREL 120 AHASELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVREL Sbjct: 61 AHASELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVREL 120 Query: 121 VKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKV 180 VKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKV Sbjct: 121 VKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKV 180 Query: 181 ETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFI 240 ETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFI Sbjct: 181 ETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFI 240 Query: 241 KRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTM 300 KRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTM Sbjct: 241 KRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTM 300 Query: 301 SPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVST 360 SPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVST Sbjct: 301 SPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVST 360 Query: 361 EIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNS 420 EIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNS Sbjct: 361 EIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNS 420 Query: 421 ISNNNIGAQASMHMSPPPEGFIDDDDDD 448 ISNNNIGAQASMHMSPPPEGFIDDDDDD Sbjct: 421 ISNNNIGAQASMHMSPPPEGFIDDDDDD 448 >ref|YP_001353014.1| signal transduction protein [Janthinobacterium sp. Marseille] gb|ABR89716.1| signal transduction protein [Janthinobacterium sp. Marseille] Length = 425 Score = 472 bits (1214), Expect = e-131, Method: Compositional matrix adjust. Identities = 238/407 (58%), Positives = 303/407 (74%), Gaps = 1/407 (0%) Query: 17 DFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVIGNLQ 76 +F+LARQPIL+ +Q L+ YELLFR A+ GPANV DD+ ATA+VIAHASELG+ NVIGN Sbjct: 18 EFFLARQPILNNDQDLVAYELLFRRASSGPANVVDDLAATASVIAHASELGIGNVIGNSL 77 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GF NVDAAVLM DF+ FLP+DKVVLEILETV +T ELV RV ELV G+ FALDDV++ S Sbjct: 78 GFFNVDAAVLMCDFVNFLPSDKVVLEILETVEITHELVERVSELVAQGFTFALDDVISHS 137 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 +++LLPL+KIIKID+ + ++L KL+ HF+ K LLAEKVET +QF C+ GF Y Sbjct: 138 DALKDLLPLIKIIKIDITGMSTTELGKLADHFRLEDKLLLAEKVETQEQFEACMKLGFHY 197 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P+IL GKKL S++ IM L+ L++ + D EI R IK+D +L LTLLRL NT Sbjct: 198 FQGYYFARPVILSGKKLAPSQLAIMQLMALIMADADTAEIERNIKKDASLVLTLLRLANT 257 Query: 257 PVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLEL 316 P G + IDSLGQAL VLGRRQL+RWLQI+L+A +K +H SPL+ LA TRGK+LEL Sbjct: 258 PGVGVTQRIDSLGQALTVLGRRQLQRWLQIILYAEHNK-GSHFTSPLLQLATTRGKLLEL 316 Query: 317 ITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFYGVA 376 IT ++RP R M++ AFTVGIMSL+D LF SME +L Q++V E+ +ALL R GFYG Sbjct: 317 ITEKLRPDNRSMADTAFTVGIMSLMDTLFSQSMEEILDQVSVVEEVTDALLYRKGFYGDL 376 Query: 377 LRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISN 423 L+L E EQ ++ A + L +LQLS +D + + AFEW N++S Sbjct: 377 LKLAEYIEQIEKTGALLIPTLQKLQLSIEDLYALQLAAFEWSNNVSG 423 >ref|YP_001100394.1| EAL domain-containing protein [Herminiimonas arsenicoxydans] emb|CAL62271.1| Conserved hypothetical protein; putative EAL domain [Herminiimonas arsenicoxydans] Length = 425 Score = 464 bits (1193), Expect = e-128, Method: Compositional matrix adjust. Identities = 233/406 (57%), Positives = 299/406 (73%), Gaps = 1/406 (0%) Query: 17 DFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVIGNLQ 76 +F+LARQPIL+ EQ+L+ YELLFR A GPANV DD+ ATA+VIAHASELG+ NVIG Sbjct: 19 EFFLARQPILNSEQNLVAYELLFRRALSGPANVVDDLAATASVIAHASELGIVNVIGASL 78 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GF NVDAAVLM DF+ FLP +KVVLEILETV VTPELV RV EL G+ FALDDV++ + Sbjct: 79 GFFNVDAAVLMRDFVNFLPCEKVVLEILETVEVTPELVARVAELSAQGFTFALDDVISHT 138 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 + +++LLPLVKIIKID+ + +++ KL +F+R K LLAEKVET++QF DC+ GF Y Sbjct: 139 EALQKLLPLVKIIKIDITGMTKAEIAKLVDYFRRDDKLLLAEKVETIEQFQDCMDLGFHY 198 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P+IL GKKL S++ +M L+ L++ + D +I IK+D +L LTLLRL NT Sbjct: 199 FQGYYFARPVILSGKKLAPSQLAVMQLMALIMADADTADIEAIIKKDASLVLTLLRLTNT 258 Query: 257 PVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLEL 316 P G + IDSL QAL VLGRRQL+RWLQI+L+A K SPL+ LA TRGK+LEL Sbjct: 259 PGLGVTRRIDSLSQALTVLGRRQLQRWLQIILYAEHHKGSQFN-SPLLQLATTRGKLLEL 317 Query: 317 ITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFYGVA 376 IT ++RPG+R M++ AFTVGIMSL+D LFG SM+ +L Q+ V ++ ALL R GFYG Sbjct: 318 ITEKLRPGQRAMADTAFTVGIMSLMDTLFGQSMQQILEQVAVVDDVSSALLARRGFYGDL 377 Query: 377 LRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSIS 422 L+L E EQ ++ A + L +LQLS +D + + AFEW N +S Sbjct: 378 LKLAEYIEQIEKTGALLVPTLQKLQLSIEDLYALQLAAFEWSNIVS 423 >ref|YP_412027.1| diguanylate phosphodiesterase [Nitrosospira multiformis ATCC 25196] gb|ABB74635.1| diguanylate phosphodiesterase (EAL domain) [Nitrosospira multiformis ATCC 25196] Length = 424 Score = 421 bits (1081), Expect = e-115, Method: Compositional matrix adjust. Identities = 217/417 (52%), Positives = 288/417 (69%), Gaps = 1/417 (0%) Query: 5 SSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHAS 64 ++ +S Q +F+LARQPIL + Q+LI YELLFR A +D A++IAH S Sbjct: 5 TAPHISSVGQVKEFFLARQPILDQNQNLIAYELLFRRAGVRAPVSAEDTRGAASIIAHTS 64 Query: 65 ELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAG 124 ELG+ NV G+ GF NV++ +LM D + FLP +KVV E +T ++TPELV RV EL KAG Sbjct: 65 ELGIENVTGSALGFFNVNSTLLMGDLVNFLPAEKVVFEFPQTDKITPELVRRVAELAKAG 124 Query: 125 YVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQ 184 Y FALDDV+ S+ I+ LLP V+IIKID + + L L FK+A+K LLA+KVETL+ Sbjct: 125 YRFALDDVITLSEYIKPLLPFVEIIKIDTSVMTYADLAMLVRQFKQARKVLLADKVETLE 184 Query: 185 QFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDV 244 QF +C GFDY+QGYYFAKP +L GKKL S++ IM L+TL+ R+ D EI + IK++V Sbjct: 185 QFQNCHELGFDYYQGYYFAKPALLSGKKLATSQLAIMELMTLVARDADTIEIEQRIKKEV 244 Query: 245 ALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLM 304 +L L+LLRLVNTP G K I SL +AL+VLGRRQL+RWLQI ++ D Q SPL+ Sbjct: 245 SLCLSLLRLVNTPAMGVTKSIHSLSEALMVLGRRQLQRWLQIQIYVGPDP-QIQFGSPLL 303 Query: 305 ILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIRE 364 +LAATRGK+LEL+ +++P R M+++AFTVGI+SL+DALFG ME +LRQI +S EI E Sbjct: 304 LLAATRGKLLELVAQKLQPANRSMADIAFTVGILSLLDALFGQHMERILRQIVLSEEITE 363 Query: 365 ALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSI 421 ALL RTGFYG L+L E E+ + + LL L L ++ + + AFEW NS+ Sbjct: 364 ALLYRTGFYGDLLKLAEYLEKPGEAGRLLVPLLARLGLPIEELYPFQLEAFEWSNSL 420 >ref|XP_002539661.1| conserved hypothetical protein [Ricinus communis] gb|EEF22722.1| conserved hypothetical protein [Ricinus communis] Length = 272 Score = 306 bits (783), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 147/255 (57%), Positives = 193/255 (75%) Query: 17 DFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVIGNLQ 76 +FYL RQPIL R Q L GYELLFR+A GPA+V +D++ATAAVIAHAS+LG+ IG+ Sbjct: 18 EFYLGRQPILDRNQALFGYELLFRNAPVGPAHVTNDLSATAAVIAHASQLGMEKTIGDAL 77 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GF+NVDA+VLMSD FLP DKVVLEIL TV++T ++V R+REL G+ FALDDV ES Sbjct: 78 GFVNVDASVLMSDIFSFLPRDKVVLEILNTVQITADVVSRIRELAGHGFRFALDDVTGES 137 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 E+ LLPLV +K+D+ + L KL+ F++ +K+L+AEKVET ++F +C+ GFDY Sbjct: 138 AEVAALLPLVDYVKMDMRNIALDTLSKLAPRFRQEKKKLVAEKVETREEFKNCLDLGFDY 197 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P+I+ GKKL S++ +M L+TL+ + DN +I R IKRDV+L+L LLRLVNT Sbjct: 198 FQGYYFARPVIMSGKKLSPSQLAVMELMTLVTSDADNHDIERAIKRDVSLALNLLRLVNT 257 Query: 257 PVYGFQKFIDSLGQA 271 P G ++ IDSL QA Sbjct: 258 PAVGARQRIDSLSQA 272 >ref|YP_286500.1| EAL [Dechloromonas aromatica RCB] gb|AAZ48030.1| EAL protein [Dechloromonas aromatica RCB] Length = 417 Score = 302 bits (774), Expect = 8e-80, Method: Compositional matrix adjust. Identities = 175/424 (41%), Positives = 260/424 (61%), Gaps = 15/424 (3%) Query: 1 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI 60 M++ ++DQ +L RQ IL REQ L YELLFR+ + A V D V ATA VI Sbjct: 1 MNEAAADQ---------LFLGRQAILDREQRLHAYELLFRNGSRNFAEVTDGVQATATVI 51 Query: 61 AHA-SELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRE 119 A+A +ELG+ +G +GFINVD L SD + LP VVLEILETV + ++ R + Sbjct: 52 ANAFTELGIEAALGQHRGFINVDEQFLFSDMLELLPRHAVVLEILETVPPSDAVIERCKA 111 Query: 120 LVKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEK 179 L AG+ ALDDV+ + ELL LV+I+K+D+ + +L++L + K K+LLAEK Sbjct: 112 LKAAGFTLALDDVIQLEPQFAELLALVEIVKVDIQPLSRVQLMQLVMKLKPMGKQLLAEK 171 Query: 180 VETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRF 239 V++ +Q C+ GF FQGYYFAKP I+ GKKL+ S++ +M L+ LL+ + D E+ Sbjct: 172 VDSREQMEQCLKLGFTLFQGYYFAKPTIIAGKKLDHSQLSLMKLMGLLLGDADTSELEAA 231 Query: 240 IKRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHT 299 +K + L++ LLR+ N+ G + I SLG A+ VLGRRQL+RWLQ+L+FA+ Q+ T Sbjct: 232 LKPEPGLTVNLLRMTNSVGAGGTERITSLGHAITVLGRRQLQRWLQLLVFASGG--QSPT 289 Query: 300 MSPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVS 359 +PL+ +AATRG+++EL+ + PG +++ AF VGIMSL+ L G + ++ + ++ Sbjct: 290 ENPLLQMAATRGRLMELLAGELSPGDNALADRAFMVGIMSLMPVLVGQPIADIVAPLGLA 349 Query: 360 TEIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQ-LSADDFFEAEKHAFEWG 418 T++R+AL +G G LR+ E +E + + AE+ L EL L A+ A +W Sbjct: 350 TDVRDALCAGSGPLGALLRIAESSE--NGNLAELATALTELPGLGPKAINRAQTQALQWA 407 Query: 419 NSIS 422 N I Sbjct: 408 NEIG 411 >ref|YP_004294711.1| diguanylate phosphodiesterase metal dependent hydrolase domain [Nitrosomonas sp. AL212] gb|ADZ26549.1| diguanylate phosphodiesterase metal dependent hydrolase domain [Nitrosomonas sp. AL212] Length = 412 Score = 293 bits (751), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 166/408 (40%), Positives = 261/408 (63%), Gaps = 6/408 (1%) Query: 18 FYLARQPILSREQHLIGYELLFRSA-AFGPANVKDDVTATAAVIAHA-SELGLSNVIGNL 75 F+L RQPIL R Q+L+ +ELLFR A ++ +D++A+A VI +A +LG+ NV+G Sbjct: 4 FFLGRQPILDRNQNLVAFELLFRQEEADEEISISNDLSASANVIINAYCQLGIQNVLGKQ 63 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 +GFIN D ++MSD I LP+ V+LEI ET +T + + R EL + GY FALD+VVA Sbjct: 64 RGFINADPGLVMSDIISLLPSKHVILEIKETTALTADFMQRCSELKQKGYQFALDNVVAI 123 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFD 195 ++++++LLPLV ++K++V+E++ ++L KL R LLA KVET +Q ++C+ GF Sbjct: 124 NEKVKQLLPLVSVVKVNVLELETNELSKLVTELNRWPVLLLALKVETREQESNCMKLGFQ 183 Query: 196 YFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVN 255 FQG+YFAKP +L K+ + K+ ++ LLTL++ + D EI + K LS L+R+VN Sbjct: 184 MFQGFYFAKPEVLSVKRADPGKLSLLKLLTLVMGDNDIEEIEKEFKHQPGLSYNLMRMVN 243 Query: 256 TPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLE 315 + G + I+S+ A++++GR+QL+RW+Q+LL+ D+ + + LM AA RGK++E Sbjct: 244 SVASGLPQKINSIKHAIMIMGRKQLQRWVQLLLYT-ADQSNENMSNALMQTAAARGKLME 302 Query: 316 LITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFYGV 375 LI T RP + E AF VGI+SL++ L G+ M+ ++ ++ + ++ +ALL R G G Sbjct: 303 LIATAERPYDKNHQERAFMVGILSLLNVLLGIEMQKIVDKLEIPDDMSQALLNREGRLGQ 362 Query: 376 ALRLVECTEQRDQDQAEMQRLLDELQ-LSADDFFEAEKHAFEWGNSIS 422 L+L+E E+ D +Q +L EL LS D + E A W N I+ Sbjct: 363 ELKLIEANEK--GDVTAIQLILAELDFLSLSDLADIEIQAIGWANRIN 408 >ref|YP_001231726.1| diguanylate phosphodiesterase [Geobacter uraniireducens Rf4] gb|ABQ27153.1| diguanylate phosphodiesterase [Geobacter uraniireducens Rf4] Length = 412 Score = 293 bits (749), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 165/413 (39%), Positives = 261/413 (63%), Gaps = 15/413 (3%) Query: 18 FYLARQPILSREQHLIGYELLFRSA-AFGPANVKDDVTATAAVIAHA-SELGLSNVIGNL 75 ++L RQPIL R+Q +IG+ELLFRSA + AN+ D A+A+VI +A ++ G V+G Sbjct: 6 YFLGRQPILDRDQQIIGFELLFRSAESLLSANISDSFQASASVIVNALTDFGTKEVLGRH 65 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 +GF NV+ +LM+D + LP ++VV+E+LET+ + +++ R R+L K G+ ALDD Sbjct: 66 KGFFNVNLDMLMNDTLELLPKEQVVIELLETIEINTDVIKRCRDLKKLGFTLALDDH-EY 124 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFD 195 S E L PL+ I+K+D++E + L + + KR LAEKVET +Q++ C GF+ Sbjct: 125 SAAYEPLYPLIDIVKLDILENSCASLSEALMPLKRWPLTFLAEKVETAEQYSFCSAHGFE 184 Query: 196 YFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVN 255 FQGYYFA P++L+ +++ +++ + LL ++R+V+ EI K++ L+ LLRLVN Sbjct: 185 LFQGYYFAHPVVLKQNRVDIAQLTLTKLLEQVLRDVELREIEETFKQNPNLTYNLLRLVN 244 Query: 256 TPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLE 315 + G ++ I +L AL+VLG +QLKRW+ + LFA+ K SPL+++AATRGK++E Sbjct: 245 SVAIGLRERIKTLRHALMVLGLQQLKRWIMLALFAS--KSVHGVFSPLLVIAATRGKLME 302 Query: 316 LITTR-----IRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRT 370 L+ + + P S+ AF GI+SLVD+LF +SME ++RQ+ ++ +IR+ALL R Sbjct: 303 LLVKKQPTLIVDP---DFSDRAFMTGILSLVDSLFEVSMEEMVRQLNLADDIRQALLTRE 359 Query: 371 GFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISN 423 G G+ L+L E EQ D A++ LL + + D A+ W NS+++ Sbjct: 360 GPLGMILQLTEKLEQADFAGADL--LLKQTDIHLDHLLRAQMETINWTNSLTD 410 >ref|YP_004694045.1| diguanylate phosphodiesterase with metal dependent hydrolase domain [Nitrosomonas sp. Is79A3] gb|AEJ00646.1| diguanylate phosphodiesterase with metal dependent hydrolase domain [Nitrosomonas sp. Is79A3] Length = 422 Score = 290 bits (743), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 163/417 (39%), Positives = 248/417 (59%), Gaps = 16/417 (3%) Query: 18 FYLARQPILSREQHLIGYELLFRSAAFG-PANVKDDVTATAAVIAHA-SELGLSNVIGNL 75 F L RQPIL R +L+ +ELLFR ANV D++A+A VI +A + G+ NV+G+ Sbjct: 4 FCLGRQPILDRNHNLVAFELLFRQEETEETANVTSDLSASANVIVNAYGKFGIHNVLGHQ 63 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 +GFIN D ++MSD I LP+ +VLE+ E+ +TPE + R +EL + GY FALD+++A Sbjct: 64 RGFINADPDLIMSDIISLLPSKHIVLEVKESASITPEFLQRCKELKQKGYQFALDNIIAI 123 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFD 195 + ++E LLPLV ++K+DV+ ++ L KL KR LLA KVE +Q C GF Sbjct: 124 NSKVELLLPLVSVVKVDVLALNQDALTKLVGELKRWPVLLLALKVENREQETYCRLLGFQ 183 Query: 196 YFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDN----------GEIVRFIKRDVA 245 FQGYYFAKP ++ K+ + K+ ++ LL L++RN D GEI KR Sbjct: 184 MFQGYYFAKPEVMSVKRADPGKVSLLKLLALVMRNNDGASENDSNSSIGEIENEFKRQPG 243 Query: 246 LSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMI 305 LS LLR+VN+ G + I+S+ A+ ++G +QL+ W+Q+LL+ + E + + + L Sbjct: 244 LSYNLLRMVNSGTDGLPQKINSIKHAIKLMGCKQLQSWIQLLLYTSNQSEDSAS-TALTQ 302 Query: 306 LAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREA 365 A RGK++ELI T RP + E A+ VGI+SL+D G+ M+ ++ ++ VS +I +A Sbjct: 303 TAVARGKLMELIATIERPHDKNHQERAYMVGILSLLDEFLGIEMQQIVDKLGVSDDISQA 362 Query: 366 LLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQ-LSADDFFEAEKHAFEWGNSI 421 L+ R G G AL+L+E E+ + + +L EL LS ++ E A W N + Sbjct: 363 LMSRHGRLGQALKLIEAKEK--GEITSIHSILSELDFLSLNELSNIETQAIGWANRL 417 >ref|YP_004694190.1| diguanylate phosphodiesterase with metal dependent hydrolase domain [Nitrosomonas sp. Is79A3] gb|AEJ00791.1| diguanylate phosphodiesterase with metal dependent hydrolase domain [Nitrosomonas sp. Is79A3] Length = 412 Score = 286 bits (733), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 165/408 (40%), Positives = 253/408 (62%), Gaps = 6/408 (1%) Query: 18 FYLARQPILSREQHLIGYELLFRSAAFG-PANVKDDVTATAAVIAHA-SELGLSNVIGNL 75 F+L RQPIL R Q+L+ +ELLFR ANV +D++A+A VI +A +LG+ NV+G Sbjct: 4 FFLGRQPILDRNQNLVAFELLFRQEETDESANVINDLSASANVIINAYCQLGIQNVLGKQ 63 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 +GFIN D ++MSD I LP VVLEI E +T E + R EL K GY FALD+VVA Sbjct: 64 RGFINADPDLVMSDIISLLPAKHVVLEIKEIALITEEFMQRCNELKKKGYQFALDNVVAM 123 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFD 195 + ++E+LLPLV ++K+D++ ++ +L +L R LLA KVE +Q C+ GF Sbjct: 124 NTKVEQLLPLVSVVKVDILALEKKELAELVTELNRWPVLLLALKVENREQETYCMQLGFQ 183 Query: 196 YFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVN 255 FQGYYFA+P +L K+ + K+ ++ LLTL++ + D EI + K LS L+R+VN Sbjct: 184 MFQGYYFARPEVLAVKRADPGKLSLLKLLTLVMGDSDIEEIEKEFKHQPGLSYNLMRMVN 243 Query: 256 TPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLE 315 + G + I+S+ A+++LGR+QL+RW+Q+LL+ + + + + LM AA RGK++E Sbjct: 244 SVASGVPQKINSIKHAIMILGRKQLQRWIQLLLYTANQSDDSMS-NALMQTAAARGKLME 302 Query: 316 LITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFYGV 375 L+ T RP + E AF VGI+SL+D L G+ M+ ++ ++ + ++ +ALL R G G Sbjct: 303 LVATTERPHDKNHQERAFMVGILSLLDVLLGIEMQQIVEKLGIPEDMSQALLAREGRLGH 362 Query: 376 ALRLVECTEQRDQDQAEMQRLLDELQ-LSADDFFEAEKHAFEWGNSIS 422 L+L+E E+ + + +Q ++ EL LS + + E A W N I Sbjct: 363 ELKLIEANEKGEVNT--VQSIITELGFLSLSELADIEIQAIGWANRIG 408