BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0022.0525.p         (503 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           15,459,386 sequences; 5,307,515,862 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|YP_003778167.1| methylmalonate-semialdehyde dehydrogenase [H...  1027   0.0  
ref|YP_004755057.1| methylmalonate-semialdehyde dehydrogenase [C...   866   0.0  
ref|YP_001355332.1| methylmalonate-semialdehyde dehydrogenase [J...   826   0.0  
ref|YP_001101643.1| methylmalonate-semialdehyde dehydrogenase, o...   814   0.0  
ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [C...   801   0.0  
ref|ZP_02883952.1| methylmalonate-semialdehyde dehydrogenase [Bu...   783   0.0  
ref|ZP_06840865.1| methylmalonate-semialdehyde dehydrogenase [Bu...   776   0.0  
ref|YP_004231781.1| methylmalonate-semialdehyde dehydrogenase [B...   775   0.0  
ref|YP_001889521.1| methylmalonate-semialdehyde dehydrogenase [B...   774   0.0  
ref|YP_001897528.1| methylmalonate-semialdehyde dehydrogenase [B...   773   0.0  

>ref|YP_003778167.1| methylmalonate-semialdehyde dehydrogenase [Herbaspirillum
           seropedicae SmR1]
 gb|ADJ66259.1| methylmalonate-semialdehyde dehydrogenase protein [Herbaspirillum
           seropedicae SmR1]
          Length = 503

 Score = 1027 bits (2656), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60
           MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA
Sbjct: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60

Query: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120
           ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL
Sbjct: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120

Query: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180
           LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD
Sbjct: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180

Query: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240
           PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT
Sbjct: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240

Query: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300
           ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA
Sbjct: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300

Query: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360
           DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK
Sbjct: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360

Query: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420
           VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL
Sbjct: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420

Query: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480
           FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY
Sbjct: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480

Query: 481 KSIMQRWSATIGKGAEFTMPVAK 503
           KSIMQRWSATIGKGAEFTMPVAK
Sbjct: 481 KSIMQRWSATIGKGAEFTMPVAK 503


>ref|YP_004755057.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans
           Ter331]
 gb|AEK64234.1| methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein
           [Collimonas fungivorans Ter331]
          Length = 506

 Score =  866 bits (2238), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 419/500 (83%), Positives = 463/500 (92%)

Query: 4   PHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWAETA 63
           P I H+ING+++ S SGR QDVFNPATGA +A+V L SV+EVN+AVAAASAAA  WA+TA
Sbjct: 7   PLIQHYINGKVAESTSGRLQDVFNPATGAVSARVVLGSVEEVNSAVAAASAAASGWADTA 66

Query: 64  PLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKT 123
           PLKRARV+F+FKEL+EQ+HDALA AIT EHGKVFSDAKGEVTRGLEIVEFA G+P LLKT
Sbjct: 67  PLKRARVMFRFKELMEQHHDALAAAITREHGKVFSDAKGEVTRGLEIVEFACGVPHLLKT 126

Query: 124 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSP 183
           QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAP+AIATGN+F+LKPSERDPSP
Sbjct: 127 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNTFILKPSERDPSP 186

Query: 184 SLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKATERA 243
           SLM+AELF +AGLPDGVFNVVQGDK+AVD LL+HP+V+AVSFVGSTPIAEYIY++   R 
Sbjct: 187 SLMMAELFHQAGLPDGVFNVVQGDKLAVDTLLQHPDVKAVSFVGSTPIAEYIYQEGARRK 246

Query: 244 GTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVADKL 303
           G +PLR QALGGAKNHLVVMPDA+LDQAVDAL+GAAYGSAGERCMAISVAVAVG+VADKL
Sbjct: 247 GAYPLRVQALGGAKNHLVVMPDADLDQAVDALMGAAYGSAGERCMAISVAVAVGNVADKL 306

Query: 304 VEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPG 363
           +EALIPRVKALK+KNGME DAEMGP+V+A HK K+E YI+ GV AGAKLLVDGRGLKV G
Sbjct: 307 IEALIPRVKALKIKNGMEADAEMGPVVSAVHKEKIEAYIEGGVAAGAKLLVDGRGLKVAG 366

Query: 364 HEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTA 423
            E+GFF+GG+LFD VT EMKIYQEEIFGPVLC+VRVPDFA+AV LINAHE+GNGV+LFT+
Sbjct: 367 LEQGFFLGGSLFDQVTPEMKIYQEEIFGPVLCIVRVPDFAAAVNLINAHEFGNGVALFTS 426

Query: 424 DGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSI 483
           DGNTA EFSRRI+VGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSI
Sbjct: 427 DGNTAREFSRRIEVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSI 486

Query: 484 MQRWSATIGKGAEFTMPVAK 503
           MQRW  TI KGAEFTMPVAK
Sbjct: 487 MQRWPQTISKGAEFTMPVAK 506


>ref|YP_001355332.1| methylmalonate-semialdehyde dehydrogenase [Janthinobacterium sp.
           Marseille]
 gb|ABR88793.1| methylmalonate-semialdehyde dehydrogenase [Janthinobacterium sp.
           Marseille]
          Length = 505

 Score =  826 bits (2134), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 403/499 (80%), Positives = 457/499 (91%), Gaps = 1/499 (0%)

Query: 6   IDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWAETAPL 65
           I H+ING+++ +  GR QDVFNPATG A+A+V LAS  +V A VA A AAAPAWA+TAPL
Sbjct: 7   IKHYINGRLTETAGGRQQDVFNPATGEASAQVVLASDADVQAVVATAKAAAPAWADTAPL 66

Query: 66  KRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKTQF 125
           KRAR+LFKFK+LIE++HD LA AIT EHGKVFSDAKGEVTRGLE+VEFA G+PQLLKTQF
Sbjct: 67  KRARILFKFKDLIEKHHDDLAAAITREHGKVFSDAKGEVTRGLEVVEFACGVPQLLKTQF 126

Query: 126 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSPSL 185
           TDNIGGGIDNWNLRQPLGVTAGITPFNFP MVP+WMAP+A+ATGN+F+LKPSERDPSPSL
Sbjct: 127 TDNIGGGIDNWNLRQPLGVTAGITPFNFPFMVPMWMAPVALATGNTFILKPSERDPSPSL 186

Query: 186 MLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRK-ATERAG 244
           M+AEL ++AGLPDGVFNV+QGDK+AVD LL+HP+V+AVSFVGSTPIAEYIY   A  + G
Sbjct: 187 MVAELLQQAGLPDGVFNVLQGDKLAVDGLLQHPDVKAVSFVGSTPIAEYIYATGAARKGG 246

Query: 245 TFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLV 304
           ++PLR QALGGAKNHLVVMPDANL+QAVDALIGAAYGSAGERCMAISVAVAVG +ADKLV
Sbjct: 247 SYPLRVQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGDIADKLV 306

Query: 305 EALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPGH 364
            ALIPRVK+LKVKNGME DAEMGP+V+AAHKAK+EGYI +GV AGAKLLVDGRGLKV GH
Sbjct: 307 AALIPRVKSLKVKNGMEADAEMGPVVSAAHKAKIEGYIDAGVKAGAKLLVDGRGLKVAGH 366

Query: 365 EEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTAD 424
           ++GFF+GG LFDHVT EM IYQEEIFGPVLCV+RVP+FA+A++LIN HE+GNGVSLFT+D
Sbjct: 367 DKGFFLGGCLFDHVTPEMTIYQEEIFGPVLCVLRVPNFAAALELINRHEFGNGVSLFTSD 426

Query: 425 GNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSIM 484
           GNTA EFSRR++VGMVGINVPIPVPMAWHSFGGWKRS+FGDTHAYGEEGI+FYTRYKSIM
Sbjct: 427 GNTAREFSRRVEVGMVGINVPIPVPMAWHSFGGWKRSMFGDTHAYGEEGIKFYTRYKSIM 486

Query: 485 QRWSATIGKGAEFTMPVAK 503
           QRW  +IGKGAEF MP +K
Sbjct: 487 QRWPESIGKGAEFAMPTSK 505


>ref|YP_001101643.1| methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein
           [Herminiimonas arsenicoxydans]
 emb|CAL63522.1| methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH)
           [Herminiimonas arsenicoxydans]
          Length = 506

 Score =  814 bits (2103), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 395/498 (79%), Positives = 449/498 (90%)

Query: 6   IDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWAETAPL 65
           I+H+ING ++ +  G  Q VFNPATG  +A V LAS  +V  AVAAA AAAPAWAE APL
Sbjct: 9   IEHYINGNLTNTVGGGQQPVFNPATGEISANVVLASDADVQTAVAAAKAAAPAWAEMAPL 68

Query: 66  KRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKTQF 125
           KRAR+LFKFK+LIE++H+ LA AIT EHGKVFSDAKGEVTRGLE+VEFA G+PQLLKTQF
Sbjct: 69  KRARILFKFKDLIERHHNDLAAAITREHGKVFSDAKGEVTRGLEVVEFACGVPQLLKTQF 128

Query: 126 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSPSL 185
           +DNIGGGIDNWNLRQPLGVTAGITPFNFP MVP+WMAP+A+ATGN+F+LKPSERDPSPSL
Sbjct: 129 SDNIGGGIDNWNLRQPLGVTAGITPFNFPFMVPMWMAPVALATGNTFILKPSERDPSPSL 188

Query: 186 MLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKATERAGT 245
           M+AEL  +AGLPDGVFNV+QGDK AVD LL+HP+++AVSFVGSTPIAEYIY+    R G+
Sbjct: 189 MVAELLHQAGLPDGVFNVLQGDKRAVDGLLQHPDIKAVSFVGSTPIAEYIYQAGAARKGS 248

Query: 246 FPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE 305
           +PLR QALGGAKNHLVVMPDANL+QAVDALIGAAYGSAGERCMAISVAVAVGSVADKLV 
Sbjct: 249 YPLRVQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVA 308

Query: 306 ALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPGHE 365
           ALIPRVK+LKVKNGME DAEMGP+V+AAHKAK+EGYI++G+ +GAKLLVDGRGL V GH 
Sbjct: 309 ALIPRVKSLKVKNGMESDAEMGPVVSAAHKAKIEGYIEAGIKSGAKLLVDGRGLTVDGHS 368

Query: 366 EGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTADG 425
            GFF+GG LFD+VT EM IYQEEIFGPVLCVVRVPDF++A+ LINAHE+GNGV+LFT+DG
Sbjct: 369 NGFFLGGCLFDNVTPEMTIYQEEIFGPVLCVVRVPDFSAALDLINAHEFGNGVALFTSDG 428

Query: 426 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSIMQ 485
           NTA EFSRR+++GMVGINVPIPVPMAWHSFGGWKRS+FGDTHAYGEEGI+FYTRYKSIMQ
Sbjct: 429 NTAREFSRRVEIGMVGINVPIPVPMAWHSFGGWKRSMFGDTHAYGEEGIKFYTRYKSIMQ 488

Query: 486 RWSATIGKGAEFTMPVAK 503
           RW  +I KGAEF MP +K
Sbjct: 489 RWPESISKGAEFAMPTSK 506


>ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans
           Ter331]
 gb|AEK59928.1| Methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans
           Ter331]
          Length = 499

 Score =  801 bits (2069), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 385/503 (76%), Positives = 429/503 (85%), Gaps = 4/503 (0%)

Query: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60
           M++P I+HFI+G  +   S R  DVFNPATGA  A+VALAS QEV+  VA+A AA PAWA
Sbjct: 1   MNIPQINHFISGTQATGRSERYSDVFNPATGAVVAQVALASTQEVDKVVASACAAFPAWA 60

Query: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120
           ET+PL+RAR++FKFKEL+EQ+HD LA  IT EHGKVFSDAKGEV RG+E+VEFA GIP L
Sbjct: 61  ETSPLRRARIMFKFKELLEQHHDQLAALITREHGKVFSDAKGEVVRGIEVVEFACGIPHL 120

Query: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180
           LKT  TDNIGGGIDNWNLRQPLGV AGITPFNFPVMVP+WM P+AIA GN F+LKPSERD
Sbjct: 121 LKTSHTDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVAIACGNCFILKPSERD 180

Query: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240
           PS SL++A+L K+AGLPDGVFNVVQGDK AVDALL HP+VQA+SFVGSTPIAEYIY +  
Sbjct: 181 PSASLLIADLLKQAGLPDGVFNVVQGDKTAVDALLAHPDVQALSFVGSTPIAEYIYTEGA 240

Query: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300
            R      R QALGGAKNHLVVMPDA+L+QAVDALIGAAYGSAGERCMAISVAVAVG VA
Sbjct: 241 RRGK----RVQALGGAKNHLVVMPDADLEQAVDALIGAAYGSAGERCMAISVAVAVGDVA 296

Query: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360
           D+LV+ L  R  ALK+ NG + D+EMGPLVT  HKAKVE Y+  GV+ GAKLLVDGRG+ 
Sbjct: 297 DRLVQQLAQRAAALKIGNGDQADSEMGPLVTGVHKAKVEAYVAKGVEEGAKLLVDGRGIS 356

Query: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420
           V GHE GFF+GGTLFDHVT EM IY+EEIFGPVL VVRVPD ASAV+L+NAHE+GNGVSL
Sbjct: 357 VAGHENGFFVGGTLFDHVTPEMTIYKEEIFGPVLSVVRVPDLASAVELVNAHEFGNGVSL 416

Query: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480
           FT+DG  A  FSR+IQVGMVGINVPIPVPMAWHSFGGWKRSLFGD HAYGEEGIRFYTRY
Sbjct: 417 FTSDGGVARAFSRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGIRFYTRY 476

Query: 481 KSIMQRWSATIGKGAEFTMPVAK 503
           KSIMQRW  +I KGAEFTMPVAK
Sbjct: 477 KSIMQRWPDSIAKGAEFTMPVAK 499


>ref|ZP_02883952.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia graminis
           C4D1M]
 gb|EDT10612.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia graminis
           C4D1M]
          Length = 507

 Score =  783 bits (2022), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 383/503 (76%), Positives = 432/503 (85%), Gaps = 5/503 (0%)

Query: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60
           +S+  I H+I G ++   SGR +DVFNPATG  T  VALASV+EV+AAV +A AA  AW+
Sbjct: 10  LSVQQIGHYIGGALAAPGSGRFKDVFNPATGKVTGSVALASVEEVDAAVKSAKAAFAAWS 69

Query: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120
           ETAPLKRAR+LF+FKEL+ ++HD LA  IT EHGKVF+DA+GEV RG+E+VEFA GIP L
Sbjct: 70  ETAPLKRARILFRFKELLNRHHDELAMLITREHGKVFTDAQGEVVRGIEVVEFACGIPNL 129

Query: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180
           LKT FTD IGGGIDNWNLRQPLGV AGITPFNFPVMVP+WM P+A+A GN+FVLKPSERD
Sbjct: 130 LKTDFTDQIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERD 189

Query: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240
           PS SL +AEL K AGLPDGVFNVV GDKVAVDAL+EHP+V A+SFVGSTPIAEYI+ +A+
Sbjct: 190 PSASLRIAELLKEAGLPDGVFNVVNGDKVAVDALIEHPDVAALSFVGSTPIAEYIHGEAS 249

Query: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300
           +R      R QALGGAKNHLVVMPDA+LDQAVDALIGAAYGSAGERCMAISVAVAVG+VA
Sbjct: 250 KRGK----RVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGNVA 305

Query: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360
           D+L+E L+PRVK+L +KNG   DAEMGPLVTA HKAKV GYI SGV+ GA L+VDGR   
Sbjct: 306 DRLIEKLVPRVKSLVIKNGENLDAEMGPLVTAEHKAKVAGYIASGVEEGATLIVDGRTHA 365

Query: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420
           V   EEGFFIGGTLFD+V T+MKIY+EEIFGPVL VVRVPDFASAV+LINAHE+GNGVSL
Sbjct: 366 V-AKEEGFFIGGTLFDNVGTQMKIYKEEIFGPVLAVVRVPDFASAVELINAHEFGNGVSL 424

Query: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480
           FT+DG  A  F R+IQVGMVGINVPIPVPMAWHSFGGWKRSLFGD HAYGEEG+RFYTRY
Sbjct: 425 FTSDGGVARAFGRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRY 484

Query: 481 KSIMQRWSATIGKGAEFTMPVAK 503
           KSIMQRW  +I KGAEFTMPVAK
Sbjct: 485 KSIMQRWPDSIAKGAEFTMPVAK 507


>ref|ZP_06840865.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia sp. Ch1-1]
 gb|EFG71585.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia sp. Ch1-1]
          Length = 507

 Score =  776 bits (2004), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 383/503 (76%), Positives = 427/503 (84%), Gaps = 5/503 (0%)

Query: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60
           +S+  + H+I G  +   SGR +DVFNPATG  T  VALASV+EV+AAV  A AA  AW+
Sbjct: 10  LSVQQLGHYIGGAPAAPTSGRFKDVFNPATGKVTGSVALASVEEVDAAVQVAKAAFSAWS 69

Query: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120
           ETAPLKRAR+LF+FKEL+ Q+HD LA  IT EHGKVF+DA+GEV RG+E+VEFA GIP L
Sbjct: 70  ETAPLKRARILFRFKELLNQHHDELAMLITREHGKVFTDAQGEVVRGIEVVEFACGIPNL 129

Query: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180
           LKT FTD IGGGIDNWNLRQ LGV AGITPFNFPVMVP+WM P+A+A GN+FVLKPSERD
Sbjct: 130 LKTDFTDQIGGGIDNWNLRQALGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERD 189

Query: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240
           PS SL +AEL K AGLPDGVFNVV GDKVAVDAL++HP+V A+SFVGSTPIAEYI+ +A+
Sbjct: 190 PSASLRIAELLKEAGLPDGVFNVVNGDKVAVDALIDHPDVAALSFVGSTPIAEYIHTEAS 249

Query: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300
           +R      R QALGGAKNHLVVMPDA+LDQAVDALIGAAYGSAGERCMAISVAVAVG+VA
Sbjct: 250 KRGK----RVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGNVA 305

Query: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360
           DKL+E L PRVK+L +KNG   DAEMGPLVTA HKAKV GYI SG   GAKL+VDGR   
Sbjct: 306 DKLIEKLAPRVKSLVIKNGENLDAEMGPLVTAEHKAKVAGYIASGEAEGAKLIVDGRVHP 365

Query: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420
           V   EEGFFIGGTLFD+V TEMKIY+EEIFGPVL VVRVPDFASAV+LINAHE+GNGVSL
Sbjct: 366 V-ADEEGFFIGGTLFDNVGTEMKIYKEEIFGPVLAVVRVPDFASAVELINAHEFGNGVSL 424

Query: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480
           FT+DG  A  F R+IQVGMVGINVPIPVPMAWHSFGGWKRSLFGD HAYGEEG+RFYTRY
Sbjct: 425 FTSDGGVARAFGRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRY 484

Query: 481 KSIMQRWSATIGKGAEFTMPVAK 503
           KSIMQRW  +I KGAEFTMPVAK
Sbjct: 485 KSIMQRWPDSIAKGAEFTMPVAK 507


>ref|YP_004231781.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia sp.
           CCGE1001]
 gb|ADX58721.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia sp.
           CCGE1001]
          Length = 507

 Score =  775 bits (2001), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 379/503 (75%), Positives = 428/503 (85%), Gaps = 5/503 (0%)

Query: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60
           +S+  + H+I G +    SGR +DVFNPAT   T  VALASV+EV+AAV +A AA PAW+
Sbjct: 10  LSVRQLGHYIGGAVVAPASGRFKDVFNPATAKVTGSVALASVEEVDAAVKSAKAAFPAWS 69

Query: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120
           ETAP+KRAR+LFKFKEL+ ++HD LA  IT EHGKVF+DA+GEV RG+E+VEFA GIP L
Sbjct: 70  ETAPIKRARILFKFKELLNRHHDELAMLITREHGKVFTDAQGEVVRGIEVVEFACGIPNL 129

Query: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180
           LKT FTD IGGGIDNWNLRQ LGV AGITPFNFPVMVP+WM P+A+A GN+FVLKPSERD
Sbjct: 130 LKTDFTDQIGGGIDNWNLRQALGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERD 189

Query: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240
           PS SL +AEL K AGLPDGVFNVV GDKVAVDAL++HP+V A+SFVGSTPIAEYI+ +A+
Sbjct: 190 PSASLRIAELLKEAGLPDGVFNVVNGDKVAVDALIDHPDVAALSFVGSTPIAEYIHTEAS 249

Query: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300
           +R      R QALGGAKNHLVVMPDA+LDQAVDALIGAAYGSAGERCMAISVAVAVG+VA
Sbjct: 250 KRGK----RVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGNVA 305

Query: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360
           DKL+E L+PRVK+L +KNG   DAEMGPLVTA HKAKV GYI SGV+ GA L+VDGR   
Sbjct: 306 DKLIEKLVPRVKSLVIKNGEHLDAEMGPLVTAEHKAKVAGYIASGVEEGANLIVDGRAHP 365

Query: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420
           V G E GFFIGGTLFD+V T MKIY+EEIFGPVL VVRVPD ASAV+LINAHE+GNGVSL
Sbjct: 366 VAG-EAGFFIGGTLFDNVGTHMKIYKEEIFGPVLAVVRVPDVASAVELINAHEFGNGVSL 424

Query: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480
           FT+DG  A  F R+IQVGMVGINVPIPVPMAWHSFGGWK+SLFGD HAYGEEG+RFYTRY
Sbjct: 425 FTSDGGVARAFGRQIQVGMVGINVPIPVPMAWHSFGGWKKSLFGDHHAYGEEGVRFYTRY 484

Query: 481 KSIMQRWSATIGKGAEFTMPVAK 503
           KSIMQRW  +I KGAEFTMPVAK
Sbjct: 485 KSIMQRWPDSIAKGAEFTMPVAK 507


>ref|YP_001889521.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia
           phytofirmans PsJN]
 gb|ACD20150.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia
           phytofirmans PsJN]
          Length = 507

 Score =  774 bits (1998), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 386/503 (76%), Positives = 430/503 (85%), Gaps = 5/503 (0%)

Query: 1   MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60
           +S+  + H+I G  +   SGR +DVFNPATG  T  VALASV+EV+AAV AA AA PAW+
Sbjct: 10  LSVQQLGHYIGGAPAAPTSGRFKDVFNPATGKVTGSVALASVEEVDAAVQAARAAFPAWS 69

Query: 61  ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120
           ETAPLKRAR+LF+FKEL+ Q+HD LA  IT EHGKVF+DA+GEV RG+E+VEFA GIP L
Sbjct: 70  ETAPLKRARILFRFKELLNQHHDELAMLITREHGKVFTDAQGEVVRGIEVVEFACGIPNL 129

Query: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180
           LKT FTD IGGGIDNWNLRQ LGV AGITPFNFPVMVP+WM P+A+A GN+FVLKPSERD
Sbjct: 130 LKTDFTDQIGGGIDNWNLRQALGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERD 189

Query: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240
           PS SL LAEL K AGLPDGVFNVV GDKVAVDAL++HP+V A+SFVGSTPIAEYI+ +A+
Sbjct: 190 PSASLRLAELLKEAGLPDGVFNVVNGDKVAVDALIDHPDVAALSFVGSTPIAEYIHTEAS 249

Query: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300
           +R      R QALGGAKNHLVVMPDA+LDQAVDALIGAAYGSAGERCMAISVAVAVG+VA
Sbjct: 250 KRGK----RVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGNVA 305

Query: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360
           DKL+E L+PRVK+L +KNG   DAEMGPLVTA HKAKV GYI SG   GAKL+VDGR   
Sbjct: 306 DKLIEKLVPRVKSLVIKNGEHLDAEMGPLVTAEHKAKVTGYIASGEAEGAKLIVDGRAHP 365

Query: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420
           V  +EEGFF+GGTLFDHV TEMKIY+EEIFGPVL VVRVPDFASAV LINAHE+GNGVSL
Sbjct: 366 VT-NEEGFFVGGTLFDHVGTEMKIYKEEIFGPVLAVVRVPDFASAVDLINAHEFGNGVSL 424

Query: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480
           FT+DG  A  F R+IQVGMVGINVPIPVPMAWHSFGGWKRSLFGD HAYGEEG+RFYTRY
Sbjct: 425 FTSDGGVARAFGRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRY 484

Query: 481 KSIMQRWSATIGKGAEFTMPVAK 503
           KSIMQRW  +I KGAEFTMPVAK
Sbjct: 485 KSIMQRWPDSIAKGAEFTMPVAK 507


>ref|YP_001897528.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia
           phytofirmans PsJN]
 gb|ACD18304.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia
           phytofirmans PsJN]
          Length = 512

 Score =  773 bits (1997), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 389/498 (78%), Positives = 434/498 (87%), Gaps = 4/498 (0%)

Query: 6   IDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWAETAPL 65
           + HFING+     SGR  DVFNPA G+ +A+V LASV EV+AAVAAA AA PAW+ETAP+
Sbjct: 19  LTHFINGKTFEGTSGRFGDVFNPAQGSVSARVPLASVAEVDAAVAAAKAAFPAWSETAPI 78

Query: 66  KRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKTQF 125
           KRARVLFKFKEL++++HD LA+ IT EHGKVFSDAKGEV RG+EIVEFA GIP LLKT F
Sbjct: 79  KRARVLFKFKELLDRHHDELAELITREHGKVFSDAKGEVMRGIEIVEFACGIPNLLKTDF 138

Query: 126 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSPSL 185
           TD IGGGIDNWNLRQPLGV AGITPFNFP+MVP WM P+AIA GN+FVLKPSERDPS S 
Sbjct: 139 TDQIGGGIDNWNLRQPLGVVAGITPFNFPMMVPCWMFPVAIACGNTFVLKPSERDPSCSN 198

Query: 186 MLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKATERAGT 245
            LAEL K AGLPDGVFNVV GDKVAVDALL HPEV A+SFVGSTPIAEYIY + T+    
Sbjct: 199 RLAELLKEAGLPDGVFNVVHGDKVAVDALLVHPEVSALSFVGSTPIAEYIYTEGTKHGK- 257

Query: 246 FPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE 305
              R QALGGAKNHLVVMPDA+LDQAVDALIGAAYGSAGERCMAISVAVAVG +AD+L+E
Sbjct: 258 ---RVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGHIADELIE 314

Query: 306 ALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPGHE 365
            L PRVK+LK+ NGME DAEMGPLVTA H+ KV GYI SGV+AGAKL+VDGRG +V GHE
Sbjct: 315 RLTPRVKSLKILNGMESDAEMGPLVTAVHREKVVGYIDSGVEAGAKLVVDGRGHQVSGHE 374

Query: 366 EGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTADG 425
           +GFF+GGTLFD+V+T+MKIY+EEIFGPVLCVVRVPDFASAV+LINA+E+ NGVSLFT+DG
Sbjct: 375 KGFFLGGTLFDNVSTDMKIYREEIFGPVLCVVRVPDFASAVELINANEFANGVSLFTSDG 434

Query: 426 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSIMQ 485
             A  FSR+IQ+GMVGINVPIPVPMAWHSFGGWK+SLFGD HAYGEEG+RFYTRYKSIMQ
Sbjct: 435 GVARAFSRQIQIGMVGINVPIPVPMAWHSFGGWKKSLFGDHHAYGEEGVRFYTRYKSIMQ 494

Query: 486 RWSATIGKGAEFTMPVAK 503
           RW  +I KGAEFTMPVAK
Sbjct: 495 RWPDSIAKGAEFTMPVAK 512