BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0417.p (386 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003778071.1| major facilitator superfamily permease [Herb... 261 2e-67 ref|YP_001351878.1| major facilitator transporter [Janthinobacte... 134 3e-29 ref|ZP_08276151.1| major facilitator superfamily MFS1 [Oxalobact... 131 2e-28 ref|YP_001098523.1| major facilitator superfamily permease [Herm... 130 4e-28 ref|YP_004754882.1| putative permease [Collimonas fungivorans Te... 107 3e-21 ref|YP_001792230.1| major facilitator transporter [Leptothrix ch... 77 5e-12 ref|ZP_08839888.1| hypothetical protein HMPREF0178_02662 [Biloph... 73 9e-11 ref|ZP_07943205.1| major facilitator superfamily transporter [Bi... 71 3e-10 ref|YP_003120622.1| major facilitator superfamily protein [Chiti... 71 3e-10 ref|ZP_08862796.1| major facilitator superfamily transporter [Ru... 70 7e-10 >ref|YP_003778071.1| major facilitator superfamily permease [Herbaspirillum seropedicae SmR1] gb|ADJ66163.1| permease of the major facilitator superfamily protein [Herbaspirillum seropedicae SmR1] Length = 400 Score = 261 bits (666), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 129/131 (98%), Positives = 129/131 (98%) Query: 1 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC 60 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC Sbjct: 16 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC 75 Query: 61 GGIGAVGSFPLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASS 120 GGIGAVGSFPLAAWITGHYGARHSSLYAGL LL SLPLLALAPGLWTLMAVCTLYGAASS Sbjct: 76 GGIGAVGSFPLAAWITGHYGARHSSLYAGLVLLLSLPLLALAPGLWTLMAVCTLYGAASS 135 Query: 121 CFDVAINALGA 131 CFDVAINALGA Sbjct: 136 CFDVAINALGA 146 >ref|YP_001351878.1| major facilitator transporter [Janthinobacterium sp. Marseille] gb|ABR91191.1| transporter of the MFS superfamily [Janthinobacterium sp. Marseille] Length = 390 Score = 134 bits (337), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 75/147 (51%), Positives = 99/147 (67%), Gaps = 3/147 (2%) Query: 1 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC 60 M+T+ + P+ + R A PFLF+LLGV++++WAARIPAIRD LQL+ A L +VLL Sbjct: 7 MSTESLLSVAPRFAR-LRSAATPFLFILLGVIYASWAARIPAIRDALQLNPAQLGMVLLG 65 Query: 61 GGIGAVGSFPLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASS 120 GG GAV SFPLAAW+ G +G R ++ Y+GL L+ LP LALAP + L+ V GA S Sbjct: 66 GGFGAVASFPLAAWLVGRFGGRRAAWYSGLGLIVVLPALALAPSMTWLVIVAVALGAGSG 125 Query: 121 CFDVAINALGAPRPSAKRAGPSCRCCM 147 CFDVAINA+G + K+AG S + Sbjct: 126 CFDVAINAIGTEQE--KQAGRSTMSLL 150 >ref|ZP_08276151.1| major facilitator superfamily MFS1 [Oxalobacteraceae bacterium IMCC9480] gb|EGF30374.1| major facilitator superfamily MFS1 [Oxalobacteraceae bacterium IMCC9480] Length = 371 Score = 131 bits (329), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 100/248 (40%), Positives = 136/248 (54%), Gaps = 27/248 (10%) Query: 19 KIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGH 78 +IA+P LF+LLG VF+TWAARIPA+RD LQL AA L LVLLC G+GAV SFPLAAW+ Sbjct: 5 RIALPILFILLGAVFATWAARIPALRDALQLGAAELGLVLLCSGVGAVLSFPLAAWLLAR 64 Query: 79 YGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALGAPRPSAKR 138 +GARH++L++GLALL +P LALAP + LM G+A+SCFDVA+NA+GA + Sbjct: 65 HGARHAALWSGLALLMLVPCLALAPRMGWLMLAMFGMGSAASCFDVAVNAIGAEVE--RV 122 Query: 139 AGPS---------CRCCMAGS--ASAPSLVHWSPAPWPAWAWRRCGISCSRRR-CWPG-R 185 AG S C +G+ SA + +H +P W C +S W + Sbjct: 123 AGRSIMSMLHAWFCLGTFSGALLGSAMAGLHVTP------LWHFCLLSAGFLLPLWLSYQ 176 Query: 186 SMPVARPCPMTVRSTIRSASSSRCRMA-IWWCWA*SPFAAPSWKGRWPTGAAST*RTTSA 244 ++P R P VR + + I +C A + W G + T + A Sbjct: 177 ALPADRIVPGAVRQQFALPHGALVALGMIAFCGAMIEGSIGDWSGIYLTD-----QLGVA 231 Query: 245 PAMAPRPW 252 P +AP + Sbjct: 232 PGVAPLGY 239 >ref|YP_001098523.1| major facilitator superfamily permease [Herminiimonas arsenicoxydans] emb|CAL60394.1| Putative Permease of the major facilitator superfamily [Herminiimonas arsenicoxydans] Length = 384 Score = 130 bits (327), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 75/128 (58%), Positives = 90/128 (70%), Gaps = 4/128 (3%) Query: 21 AIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYG 80 A PFLF+LLGV++++WAARIPAIRD LQL A L +VLL GG GAV SFPLAAW+ G +G Sbjct: 20 ATPFLFILLGVIYASWAARIPAIRDVLQLSPAQLGMVLLGGGFGAVASFPLAAWLVGRFG 79 Query: 81 ARHSSLYAGLALLFSLPLLALAPG-LWTLMAVCTLYGAASSCFDVAINALGAPRPSAKRA 139 R ++ YAGL L+ LP LALAP LW ++A L GAAS CFDVAINA+G K A Sbjct: 80 GRRAAWYAGLGLIVVLPALALAPNMLWLVIAAIVL-GAASGCFDVAINAIGTAHE--KLA 136 Query: 140 GPSCRCCM 147 G S + Sbjct: 137 GRSTMSLL 144 >ref|YP_004754882.1| putative permease [Collimonas fungivorans Ter331] gb|AEK64059.1| Putative Permease of the major facilitator superfamily [Collimonas fungivorans Ter331] Length = 402 Score = 107 bits (268), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 69/114 (60%), Positives = 83/114 (72%), Gaps = 2/114 (1%) Query: 30 GVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYGARHSSLYAG 89 GV++++W +RIPA+RD LQLD A+L+L LL GGIGAV SFPLAAW+ GHYGAR + YAG Sbjct: 47 GVIYASWVSRIPALRDHLQLDPASLSLFLLGGGIGAVSSFPLAAWLIGHYGARRACWYAG 106 Query: 90 LALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALGAPRPSAKRAGPSC 143 LALL ++P LALAP L LM G SS F+VAINALGA + K AG S Sbjct: 107 LALLLAIPCLALAPSLPLLMLAMLYLGVCSSSFNVAINALGA--EAEKIAGRSI 158 >ref|YP_001792230.1| major facilitator transporter [Leptothrix cholodnii SP-6] gb|ACB35465.1| major facilitator superfamily MFS_1 [Leptothrix cholodnii SP-6] Length = 401 Score = 77.0 bits (188), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 44/106 (41%), Positives = 61/106 (57%) Query: 25 LFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYGARHS 84 LF LGV+ W A IP+++ LD A+L+LVL C IGAV S +A + G GAR + Sbjct: 37 LFGALGVLGGVWGAHIPSLKSVYGLDEASLSLVLFCAAIGAVSSLFVAGRVIGRLGARRT 96 Query: 85 SLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALG 130 +L GL + + L P ++ LM C +G + S +DVAINA G Sbjct: 97 ALVTGLVMAAAQATALLWPSVYFLMFACLFFGTSMSIYDVAINAEG 142 >ref|ZP_08839888.1| hypothetical protein HMPREF0178_02662 [Bilophila sp. 4_1_30] gb|EGW44537.1| hypothetical protein HMPREF0178_02662 [Bilophila sp. 4_1_30] Length = 380 Score = 72.8 bits (177), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 46/115 (40%), Positives = 68/115 (59%), Gaps = 6/115 (5%) Query: 14 HQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAA 73 Q +IA +L+LGV S+WAA +P + +L LD A L ++LLC G+G++ S P Sbjct: 15 EQITTRIA----YLILGVGVSSWAALVPYAKTRLGLDEAVLGMLLLCVGVGSLLSMPFTG 70 Query: 74 WITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCT-LYGAASSCFDVAIN 127 I+G +G R L +G+ L LPLLA +W LMA+C L+GA+ DV++ Sbjct: 71 LISGRFGCRKVILVSGVIFLAMLPLLASVESIW-LMALCLFLFGASIGMMDVSLT 124 >ref|ZP_07943205.1| major facilitator superfamily transporter [Bilophila wadsworthia 3_1_6] gb|EFV45624.1| major facilitator superfamily transporter [Bilophila wadsworthia 3_1_6] Length = 380 Score = 71.2 bits (173), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 46/115 (40%), Positives = 67/115 (58%), Gaps = 6/115 (5%) Query: 14 HQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAA 73 Q +IA +L+LGV S+WAA +P + +L LD A L ++LLC G+G++ S P Sbjct: 15 EQITTRIA----YLVLGVGVSSWAALVPYAKARLGLDEAVLGMLLLCVGVGSLLSMPFTG 70 Query: 74 WITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCT-LYGAASSCFDVAIN 127 I+G +G R L +G L LPLLA +W LMA+C L+GA+ DV++ Sbjct: 71 LISGRFGCRKVILVSGFIFLAMLPLLASVESVW-LMALCLFLFGASIGMMDVSLT 124 >ref|YP_003120622.1| major facilitator superfamily protein [Chitinophaga pinensis DSM 2588] gb|ACU58421.1| major facilitator superfamily MFS_1 [Chitinophaga pinensis DSM 2588] Length = 385 Score = 71.2 bits (173), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 45/123 (36%), Positives = 68/123 (55%), Gaps = 2/123 (1%) Query: 7 IPALPQNHQAWR--KIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIG 64 + L +H R +IA+ LF L G+ FS+WA+RIPAI+ +L L L +LL IG Sbjct: 2 LQELTVSHSQKRITRIAVSALFFLTGLCFSSWASRIPAIQHKLNLSEGELGGMLLALPIG 61 Query: 65 AVGSFPLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDV 124 ++ S P+A + YG+R+ + AGL F LP L L W L + L+G + ++ Sbjct: 62 SILSMPVAGILVSRYGSRYVLMTAGLLYAFILPTLGLTSTAWQLFSCLILFGFCGNLANI 121 Query: 125 AIN 127 A+N Sbjct: 122 AVN 124 >ref|ZP_08862796.1| major facilitator superfamily transporter [Ruegeria sp. TW15] Length = 378 Score = 69.7 bits (169), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 47/113 (41%), Positives = 63/113 (55%), Gaps = 2/113 (1%) Query: 16 AWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWI 75 AWR +A +F+L G +F WA+RIPA+RD+L+L L LL GAV SFP+ + Sbjct: 7 AWRAVAA--MFILNGALFGIWASRIPAVRDRLELSHEALGYGLLFMAAGAVCSFPITGKL 64 Query: 76 TGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINA 128 T +GA + + SL LLA A G W L A ++GA DVA+NA Sbjct: 65 TDRFGAVAITRIIAVLYTASLILLAFANGFWALTAFLFVFGAFHGSMDVAMNA 117