BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0412.p (302 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003778068.1| hydroxymethylglutaryl-CoA lyase [Herbaspiril... 615 e-174 ref|YP_001351814.1| hydroxymethylglutaryl-CoA lyase [Janthinobac... 514 e-144 emb|CAL60339.2| Hydroxymethylglutaryl-CoA lyase (HMG-CoA lyase) ... 504 e-141 ref|YP_004754893.1| hydroxymethylglutaryl-CoA lyase [Collimonas ... 472 e-131 ref|ZP_06843685.1| pyruvate carboxyltransferase [Burkholderia sp... 456 e-126 ref|YP_001098468.1| putative hydroxymethylglutaryl-CoA lyase [He... 449 e-124 ref|YP_440871.1| hydroxymethylglutaryl-CoA lyase [Burkholderia t... 448 e-124 ref|YP_001633348.1| hydroxymethylglutaryl-CoA lyase [Bordetella ... 446 e-123 ref|ZP_02372445.1| hydroxymethylglutaryl-CoA lyase [Burkholderia... 446 e-123 ref|YP_106960.1| hydroxymethylglutaryl-CoA lyase [Burkholderia p... 446 e-123 >ref|YP_003778068.1| hydroxymethylglutaryl-CoA lyase [Herbaspirillum seropedicae SmR1] gb|ADJ66160.1| hydroxymethylglutaryl-CoA lyase protein [Herbaspirillum seropedicae SmR1] Length = 302 Score = 615 bits (1587), Expect = e-174, Method: Compositional matrix adjust. Identities = 301/302 (99%), Positives = 302/302 (100%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA Sbjct: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 TSAEVMHGITR+PGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES Sbjct: 61 TSAEVMHGITRRPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI Sbjct: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC Sbjct: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR Sbjct: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 Query: 301 AG 302 AG Sbjct: 301 AG 302 >ref|YP_001351814.1| hydroxymethylglutaryl-CoA lyase [Janthinobacterium sp. Marseille] gb|ABR88598.1| hydroxymethylglutaryl-CoA lyase [Janthinobacterium sp. Marseille] Length = 309 Score = 514 bits (1325), Expect = e-144, Method: Compositional matrix adjust. Identities = 249/299 (83%), Positives = 272/299 (90%) Query: 2 NLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMAT 61 +LP VKI+EVGPRDGLQNE+ TISAE KIELVNRL+ AGFPNVEAASFVSPKWVPQMAT Sbjct: 6 SLPASVKIIEVGPRDGLQNEQQTISAETKIELVNRLSQAGFPNVEAASFVSPKWVPQMAT 65 Query: 62 SAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAESI 121 S+EVM GITR+PG +YSALVPNMKGFEAAL AGVDEVVIF AASEAFSQKNINCSIAESI Sbjct: 66 SSEVMAGITRRPGTLYSALVPNMKGFEAALAAGVDEVVIFAAASEAFSQKNINCSIAESI 125 Query: 122 DRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTIG 181 RF +VA+AAK+H RLR A+SCAFGCPYQGEV ++VADVVR+ RELGCDEIDIADTIG Sbjct: 126 ARFRDVAQAAKQHHLRLRGALSCAFGCPYQGEVTADSVADVVRQLRELGCDEIDIADTIG 185 Query: 182 VATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGCP 241 VATP V+ VM+ AI EF I+ LSGHFHDTYGQALANIYASL+ GISIYHASVAGLGGCP Sbjct: 186 VATPRHVQAVMQRAIGEFPIDRLSGHFHDTYGQALANIYASLEVGISIYHASVAGLGGCP 245 Query: 242 YAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 YAKGATGNVATEDVLYMM G GIETG+DLDAVV+AGQFIS+QLGR++VSRAGNAIAAKR Sbjct: 246 YAKGATGNVATEDVLYMMQGFGIETGIDLDAVVDAGQFISEQLGRKAVSRAGNAIAAKR 304 >emb|CAL60339.2| Hydroxymethylglutaryl-CoA lyase (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase) [Herminiimonas arsenicoxydans] Length = 305 Score = 504 bits (1299), Expect = e-141, Method: Compositional matrix adjust. Identities = 242/299 (80%), Positives = 272/299 (90%) Query: 2 NLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMAT 61 +LPK VKI+EVGPRDGLQNE+ TISA+VKIELVNRL+ AGF N+EAASFVSPKWVPQMAT Sbjct: 5 SLPKAVKIIEVGPRDGLQNEQQTISADVKIELVNRLSQAGFVNIEAASFVSPKWVPQMAT 64 Query: 62 SAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAESI 121 SAEVM GITR+PG +YSALVPNMKGFEAAL AGVDEVVIF AASEAFSQKNINCSIAES+ Sbjct: 65 SAEVMAGITRRPGTLYSALVPNMKGFEAALAAGVDEVVIFAAASEAFSQKNINCSIAESV 124 Query: 122 DRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTIG 181 +RF +VARAAKE++ RLR A+SCAFGCPYQGEV ++VA VV++ R+LGCDEIDIADTIG Sbjct: 125 ERFRDVARAAKENKLRLRGALSCAFGCPYQGEVSADSVASVVQQLRDLGCDEIDIADTIG 184 Query: 182 VATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGCP 241 VATP V+ VM+ A +EF IE LSGHFHDTYGQALANIYASL+ GI+IYHASVAGLGGCP Sbjct: 185 VATPRHVQAVMQRAAQEFPIEKLSGHFHDTYGQALANIYASLEVGITIYHASVAGLGGCP 244 Query: 242 YAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 YAKGATGNVATEDVLYM+ GLGI TG+DLD VV+AGQFIS QLGR++VSRAGNA+AAKR Sbjct: 245 YAKGATGNVATEDVLYMLRGLGIATGIDLDKVVDAGQFISAQLGRKAVSRAGNALAAKR 303 >ref|YP_004754893.1| hydroxymethylglutaryl-CoA lyase [Collimonas fungivorans Ter331] gb|AEK64070.1| Hydroxymethylglutaryl-CoA lyase [Collimonas fungivorans Ter331] Length = 307 Score = 472 bits (1215), Expect = e-131, Method: Compositional matrix adjust. Identities = 237/300 (79%), Positives = 265/300 (88%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 M P KVKIVEVGPRDGLQNEK+TI A+VKI LV++L AGF N+EAASFVSPKWVPQMA Sbjct: 6 MTFPSKVKIVEVGPRDGLQNEKETIPADVKIALVDQLTKAGFVNIEAASFVSPKWVPQMA 65 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 TS+EVM I RKPGVVYSALVPNMKG EAAL AG DE+VIFGAASEAFSQKNINCSIAES Sbjct: 66 TSSEVMAAIQRKPGVVYSALVPNMKGLEAALAAGADEMVIFGAASEAFSQKNINCSIAES 125 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 I+RF EVA+ AK+ KRLR ++SCAFGCPYQGEV + +V DV+ R R+LGCDEIDIADTI Sbjct: 126 IERFREVAQVAKQEGKRLRGSISCAFGCPYQGEVGIASVVDVLHRLRDLGCDEIDIADTI 185 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GVATP KV VM+ ++EF IE LSGHFHDTYGQALANIYASL+ GISIYH+SVAGLGGC Sbjct: 186 GVATPNKVHAVMQRLVQEFPIERLSGHFHDTYGQALANIYASLEVGISIYHSSVAGLGGC 245 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 PYAKGATGNV++EDVLY+M GLGIETG+DLDAVV+AGQFIS LGR++VSRAGNAIAAKR Sbjct: 246 PYAKGATGNVSSEDVLYLMQGLGIETGIDLDAVVDAGQFISAHLGRKAVSRAGNAIAAKR 305 >ref|ZP_06843685.1| pyruvate carboxyltransferase [Burkholderia sp. Ch1-1] gb|EFG68769.1| pyruvate carboxyltransferase [Burkholderia sp. Ch1-1] Length = 308 Score = 456 bits (1172), Expect = e-126, Method: Compositional matrix adjust. Identities = 222/299 (74%), Positives = 247/299 (82%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 M LP++VKIVEVGPRDGLQNEK+ + KIEL+NRL+AAGF NVEAASFVSPKWVPQMA Sbjct: 1 MALPQQVKIVEVGPRDGLQNEKEFVPTATKIELINRLSAAGFRNVEAASFVSPKWVPQMA 60 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 A+VM GI R+PG +YS L PN++GFE AL A DE+VIFGAASEAFSQKNINCSIAES Sbjct: 61 DGADVMAGIERRPGTIYSVLTPNLRGFEGALAARADEIVIFGAASEAFSQKNINCSIAES 120 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 IDRFA VA+AAKEH R+R +VSCA GCPYQGEVP+ +VADVV RF LGCDEIDIADTI Sbjct: 121 IDRFAPVAQAAKEHGVRIRGSVSCALGCPYQGEVPVASVADVVERFAALGCDEIDIADTI 180 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GV TP + R V E R F + LSGHFHDTYGQALANIYA+L GI IYHASVAGLGGC Sbjct: 181 GVGTPKRTREVFEAVTRVFPRKRLSGHFHDTYGQALANIYAALLEGIEIYHASVAGLGGC 240 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAK 299 PYAKGATGNVATEDVLY+MNGLGIETG+DL VV G FIS +GR +VSRAG A+ AK Sbjct: 241 PYAKGATGNVATEDVLYLMNGLGIETGIDLAQVVAIGDFISTSIGRPNVSRAGKALLAK 299 >ref|YP_001098468.1| putative hydroxymethylglutaryl-CoA lyase [Herminiimonas arsenicoxydans] Length = 269 Score = 449 bits (1154), Expect = e-124, Method: Compositional matrix adjust. Identities = 215/267 (80%), Positives = 242/267 (90%) Query: 34 VNRLAAAGFPNVEAASFVSPKWVPQMATSAEVMHGITRKPGVVYSALVPNMKGFEAALEA 93 +NRL+ AGF N+EAASFVSPKWVPQMATSAEVM GITR+PG +YSALVPNMKGFEAAL A Sbjct: 1 MNRLSQAGFVNIEAASFVSPKWVPQMATSAEVMAGITRRPGTLYSALVPNMKGFEAALAA 60 Query: 94 GVDEVVIFGAASEAFSQKNINCSIAESIDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGE 153 GVDEVVIF AASEAFSQKNINCSIAES++RF +VARAAKE++ RLR A+SCAFGCPYQGE Sbjct: 61 GVDEVVIFAAASEAFSQKNINCSIAESVERFRDVARAAKENKLRLRGALSCAFGCPYQGE 120 Query: 154 VPLEAVADVVRRFRELGCDEIDIADTIGVATPGKVRPVMETAIREFHIEGLSGHFHDTYG 213 V ++VA VV++ R+LGCDEIDIADTIGVATP V+ VM+ A +EF IE LSGHFHDTYG Sbjct: 121 VSADSVASVVQQLRDLGCDEIDIADTIGVATPRHVQAVMQRAAQEFPIEKLSGHFHDTYG 180 Query: 214 QALANIYASLQTGISIYHASVAGLGGCPYAKGATGNVATEDVLYMMNGLGIETGVDLDAV 273 QALANIYASL+ GI+IYHASVAGLGGCPYAKGATGNVATEDVLYM+ GLGI TG+DLD V Sbjct: 181 QALANIYASLEVGITIYHASVAGLGGCPYAKGATGNVATEDVLYMLRGLGIATGIDLDKV 240 Query: 274 VEAGQFISQQLGRRSVSRAGNAIAAKR 300 V+AGQFIS QLGR++VSRAGNA+AAKR Sbjct: 241 VDAGQFISAQLGRKAVSRAGNALAAKR 267 >ref|YP_440871.1| hydroxymethylglutaryl-CoA lyase [Burkholderia thailandensis E264] ref|ZP_02386296.1| hydroxymethylglutaryl-CoA lyase [Burkholderia thailandensis Bt4] ref|ZP_05588736.1| hydroxymethylglutaryl-CoA lyase [Burkholderia thailandensis E264] gb|ABC38657.1| hydroxymethylglutaryl-CoA lyase [Burkholderia thailandensis E264] Length = 310 Score = 448 bits (1153), Expect = e-124, Method: Compositional matrix adjust. Identities = 221/300 (73%), Positives = 247/300 (82%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 M LP+ VKIVEVGPRDGLQNE+ + +VKIELVNRL+ AGF NVEAASFVSPKWVPQMA Sbjct: 1 MTLPQSVKIVEVGPRDGLQNEQAFVPTDVKIELVNRLSRAGFRNVEAASFVSPKWVPQMA 60 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 A+VM GI R+ G VYSAL PN+KGFE AL A DEVVIFGAASEAFSQ+NINCSIAES Sbjct: 61 DGADVMAGIERRAGTVYSALTPNLKGFENALAARADEVVIFGAASEAFSQRNINCSIAES 120 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 I RF VARAAK+ RLRA+VSCA GCPYQG+VP+ AV DVV R LGCDEIDIADTI Sbjct: 121 IARFEPVARAAKDAGVRLRASVSCALGCPYQGDVPIAAVVDVVERLAALGCDEIDIADTI 180 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GV TPG+ R V++ A + F E LSGHFHDTYGQALANIYA+L G++I+HASVAGLGGC Sbjct: 181 GVGTPGRTRAVLDAAAKVFARERLSGHFHDTYGQALANIYAALLEGVAIFHASVAGLGGC 240 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 PYAKGATGNVATEDVLYMM GL I+TGVDLD VV AG FIS +GR +VSRAG A+ AK+ Sbjct: 241 PYAKGATGNVATEDVLYMMRGLNIDTGVDLDQVVAAGDFISNAIGRANVSRAGRALLAKQ 300 >ref|YP_001633348.1| hydroxymethylglutaryl-CoA lyase [Bordetella petrii DSM 12804] emb|CAP45081.1| hydroxymethylglutaryl-CoA lyase [Bordetella petrii] Length = 302 Score = 446 bits (1148), Expect = e-123, Method: Compositional matrix adjust. Identities = 215/301 (71%), Positives = 244/301 (81%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 M LP +VKIVEV PRDGLQNEK+ IS ++K+ELV+RL AAGFPN+EA SFVSPKWVPQMA Sbjct: 1 MPLPSRVKIVEVSPRDGLQNEKELISTDIKVELVDRLTAAGFPNIEATSFVSPKWVPQMA 60 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 + +VM I RKPGV+YS L PNMKG E AL A DEVVIFGAASEAFSQKNINCSIAES Sbjct: 61 DATDVMARIQRKPGVIYSVLTPNMKGLEGALAAKADEVVIFGAASEAFSQKNINCSIAES 120 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 I RF VA AA+ RLR ++SCA GCPYQGEVP+EAV DV RR+ LGCDEID+ADTI Sbjct: 121 ITRFEPVAEAARAAGVRLRGSISCALGCPYQGEVPIEAVVDVARRYVALGCDEIDVADTI 180 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GV TP +VR VM + +SGHFHDTYGQALANI A+L+TGISI+H SVAGLGGC Sbjct: 181 GVGTPQRVRDVMTAVTQVVDPGRVSGHFHDTYGQALANILAALETGISIFHTSVAGLGGC 240 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 PYAKGATGNVATEDVLYM+ GLGI TG+D DAVV+ GQ++S L R+ SRAGNA+AAKR Sbjct: 241 PYAKGATGNVATEDVLYMLRGLGINTGIDFDAVVDIGQWMSAHLNRKGGSRAGNAVAAKR 300 Query: 301 A 301 A Sbjct: 301 A 301 >ref|ZP_02372445.1| hydroxymethylglutaryl-CoA lyase [Burkholderia thailandensis TXDOH] Length = 310 Score = 446 bits (1148), Expect = e-123, Method: Compositional matrix adjust. Identities = 220/300 (73%), Positives = 246/300 (82%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 M LP+ VKIVEVGPRDGLQNE+ + +VKI LVNRL+ AGF NVEAASFVSPKWVPQMA Sbjct: 1 MTLPQSVKIVEVGPRDGLQNEQAFVPTDVKIALVNRLSRAGFRNVEAASFVSPKWVPQMA 60 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 A+VM GI R+ G VYSAL PN+KGFE AL A DEVVIFGAASEAFSQ+NINCSIAES Sbjct: 61 DGADVMAGIERRAGTVYSALTPNLKGFENALAARADEVVIFGAASEAFSQRNINCSIAES 120 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 I RF VARAAK+ RLRA+VSCA GCPYQG+VP+ AV DVV R LGCDEIDIADTI Sbjct: 121 IARFEPVARAAKDAGVRLRASVSCALGCPYQGDVPIAAVVDVVERLAALGCDEIDIADTI 180 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GV TPG+ R V++ A + F E LSGHFHDTYGQALANIYA+L G++I+HASVAGLGGC Sbjct: 181 GVGTPGRTRAVLDAAAKVFARERLSGHFHDTYGQALANIYAALLEGVAIFHASVAGLGGC 240 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 PYAKGATGNVATEDVLYMM GL I+TGVDLD VV AG FIS +GR +VSRAG A+ AK+ Sbjct: 241 PYAKGATGNVATEDVLYMMRGLNIDTGVDLDQVVAAGDFISNAIGRANVSRAGRALLAKQ 300 >ref|YP_106960.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei K96243] ref|YP_331957.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1710b] ref|YP_001057406.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 668] ref|YP_001064650.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1106a] ref|ZP_02409558.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 14] ref|ZP_02445567.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 91] ref|ZP_02453875.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 9] ref|ZP_02469499.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei B7210] ref|ZP_02479897.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 7894] ref|ZP_02488199.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei NCTC 13177] ref|ZP_02496301.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 112] ref|ZP_02504335.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei BCC215] ref|ZP_03457140.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 576] ref|YP_002894999.1| hydroxymethylglutaryl-CoA lyase, (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase) [Burkholderia pseudomallei MSHR346] ref|ZP_04816908.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1106b] ref|ZP_04888666.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1655] ref|ZP_04894512.1| HMGL-like protein [Burkholderia pseudomallei Pasteur 52237] ref|ZP_04902623.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei S13] ref|ZP_04951343.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1710a] emb|CAH34322.1| putative hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei K96243] gb|ABA47965.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1710b] gb|ABN83562.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 668] gb|ABN89809.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1106a] gb|EDO91350.1| HMGL-like protein [Burkholderia pseudomallei Pasteur 52237] gb|EDS85635.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei S13] gb|EDU09650.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1655] gb|EEC31356.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 576] gb|ACQ95728.1| hydroxymethylglutaryl-CoA lyase, (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase) [Burkholderia pseudomallei MSHR346] gb|EES27533.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1106b] gb|EET08362.1| hydroxymethylglutaryl-CoA lyase [Burkholderia pseudomallei 1710a] Length = 311 Score = 446 bits (1146), Expect = e-123, Method: Compositional matrix adjust. Identities = 220/300 (73%), Positives = 245/300 (81%) Query: 1 MNLPKKVKIVEVGPRDGLQNEKDTISAEVKIELVNRLAAAGFPNVEAASFVSPKWVPQMA 60 M LP+ VKIVEVGPRDGLQNE+ + VKIELVNRL+ AGF NVEAASFVSPKWVPQMA Sbjct: 1 MTLPQSVKIVEVGPRDGLQNEQTFVPTGVKIELVNRLSQAGFRNVEAASFVSPKWVPQMA 60 Query: 61 TSAEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 120 A+VM GI R+ G +YSAL PN+KG E AL A DEVVIFGAASEAFS++NINCSIAES Sbjct: 61 DGADVMAGIARRAGTIYSALTPNLKGVENALAARADEVVIFGAASEAFSRRNINCSIAES 120 Query: 121 IDRFAEVARAAKEHRKRLRAAVSCAFGCPYQGEVPLEAVADVVRRFRELGCDEIDIADTI 180 I RF VARAAK+ RLRA+VSCA GCPYQG+VPLEAV DVV R LGCDEIDIADTI Sbjct: 121 IARFEPVARAAKDAGVRLRASVSCALGCPYQGDVPLEAVVDVVERLAALGCDEIDIADTI 180 Query: 181 GVATPGKVRPVMETAIREFHIEGLSGHFHDTYGQALANIYASLQTGISIYHASVAGLGGC 240 GV TPG+ R V++ + F E LSGHFHDTYGQALANIYA+L GI+I+HASVAGLGGC Sbjct: 181 GVGTPGRTRAVLDAVAKAFPRERLSGHFHDTYGQALANIYAALLEGIAIFHASVAGLGGC 240 Query: 241 PYAKGATGNVATEDVLYMMNGLGIETGVDLDAVVEAGQFISQQLGRRSVSRAGNAIAAKR 300 PYAKGATGNVATEDVLYMM GL IETGVDLD VV AG FIS +GR ++SRAG A+ AK+ Sbjct: 241 PYAKGATGNVATEDVLYMMRGLNIETGVDLDQVVAAGDFISNAIGRANISRAGRALLAKQ 300