BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0366.p (497 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003778022.1| methylmalonate-semialdehyde dehydrogenase [H... 999 0.0 ref|YP_001887998.1| methylmalonate-semialdehyde dehydrogenase [B... 748 0.0 ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [C... 738 0.0 ref|YP_004687388.1| methylmalonate-semialdehyde dehydrogenase Mm... 719 0.0 ref|YP_004684127.1| methylmalonate-semialdehyde dehydrogenase Mm... 715 0.0 ref|YP_294475.1| methylmalonate-semialdehyde dehydrogenase [acyl... 712 0.0 ref|YP_728089.1| methylmalonate-semialdehyde dehydrogenase [Rals... 709 0.0 ref|YP_724792.1| methylmalonate-semialdehyde dehydrogenase [Rals... 709 0.0 ref|ZP_07673516.1| methylmalonate-semialdehyde dehydrogenase (ac... 706 0.0 ref|YP_002290472.1| methylmalonate-semialdehyde dehydrogenase [O... 706 0.0 >ref|YP_003778022.1| methylmalonate-semialdehyde dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ66114.1| methylmalonate-semialdehyde dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 497 Score = 999 bits (2583), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/497 (98%), Positives = 495/497 (99%) Query: 1 MEKIAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNT 60 MEKIAHYIGGQRVDT+SGRYADVFNPAQGVPVAQVALGTSDEVDAAV+AGVAAFPAWSNT Sbjct: 1 MEKIAHYIGGQRVDTRSGRYADVFNPAQGVPVAQVALGTSDEVDAAVKAGVAAFPAWSNT 60 Query: 61 PPLTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLK 120 PPLTRARVLFRFLHLIQQRADD ARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLK Sbjct: 61 PPLTRARVLFRFLHLIQQRADDFARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLK 120 Query: 121 GEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPS 180 GEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPS Sbjct: 121 GEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPS 180 Query: 181 ASLLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAK 240 ASLLIADLLKEAGLPDGVFNV+QGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAK Sbjct: 181 ASLLIADLLKEAGLPDGVFNVVQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAK 240 Query: 241 GKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAA 300 GKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVA+AVGSAGDELVAA Sbjct: 241 GKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVALAVGSAGDELVAA 300 Query: 301 LAERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEK 360 LAERA KLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEK Sbjct: 301 LAERARKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEK 360 Query: 361 GFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGG 420 GFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGG Sbjct: 361 GFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGG 420 Query: 421 VAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQR 480 VAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQR Sbjct: 421 VAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQR 480 Query: 481 WPNTASAGAEFAFPQMK 497 WPNTASAGAEFAFPQMK Sbjct: 481 WPNTASAGAEFAFPQMK 497 >ref|YP_001887998.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia phytofirmans PsJN] gb|ACD18628.1| methylmalonate-semialdehyde dehydrogenase [Burkholderia phytofirmans PsJN] Length = 501 Score = 748 bits (1930), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/498 (76%), Positives = 438/498 (87%), Gaps = 5/498 (1%) Query: 1 MEKIAHYIGGQRVDTKSGRYAD---VFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAW 57 +E I+H+I GQR T S R A+ VFNPA G VAQVA+G+++++ AAV A AAFPAW Sbjct: 4 LETISHFINGQR--TASLRNAETQAVFNPALGEAVAQVAMGSAEDIHAAVGAAAAAFPAW 61 Query: 58 SNTPPLTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQ 117 S PPL RAR+L ++L L+QQ D +A+++ REHGKT DA+GEVARG+E+VEFA GIP Sbjct: 62 SARPPLARARILAKYLQLMQQHTDTLAQMLTREHGKTLDDARGEVARGLEVVEFAVGIPH 121 Query: 118 MLKGEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSER 177 +LKGE++DQI+RGIDAWS+RQ LGVVAGITPFNFPAMVPMWMFPIA+ACGN FVLKPSER Sbjct: 122 LLKGEFSDQISRGIDAWSIRQPLGVVAGITPFNFPAMVPMWMFPIALACGNTFVLKPSER 181 Query: 178 DPSASLLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARG 237 DPS SLL A+LLKEAGLPDGVFNV+QGDK VDALLDHP+V+A+SFVGSTPIAEY+YAR Sbjct: 182 DPSCSLLHAELLKEAGLPDGVFNVVQGDKAVVDALLDHPEVQAVSFVGSTPIAEYVYARA 241 Query: 238 SAKGKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDEL 297 SA GKR QALGGAKNH+VVMPDADM +A DAL+GAA+GSAGERCMAISVAVAVG GD L Sbjct: 242 SANGKRAQALGGAKNHLVVMPDADMAMATDALIGAAFGSAGERCMAISVAVAVGDVGDRL 301 Query: 298 VAALAERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPG 357 VAALAER LKI++G A GAEMGPV+TAAA+ERIE LIG GV +GATLVVDGR Y+VPG Sbjct: 302 VAALAERTRALKIDDGTAPGAEMGPVITAAARERIESLIGAGVADGATLVVDGRDYRVPG 361 Query: 358 FEKGFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTR 417 E GFFVGGTL DHVTPEMTVY+EEIFGPVLCV+R P++A+AVELINAHEYGNGVAV+TR Sbjct: 362 RESGFFVGGTLFDHVTPEMTVYREEIFGPVLCVVRVPNVAAAVELINAHEYGNGVAVFTR 421 Query: 418 DGGVAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAV 477 DGGVAREF RQ+++GMVGVNVP+PVPMAF+SFGGWKRSLFGDHH+YGPEGVRFYTR KAV Sbjct: 422 DGGVAREFTRQVQIGMVGVNVPVPVPMAFNSFGGWKRSLFGDHHIYGPEGVRFYTRHKAV 481 Query: 478 MQRWPNTASAGAEFAFPQ 495 MQRWP+T +AGAEFAFPQ Sbjct: 482 MQRWPDTITAGAEFAFPQ 499 >ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK59928.1| Methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 499 Score = 738 bits (1905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/495 (69%), Positives = 406/495 (82%) Query: 3 KIAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNTPP 62 +I H+I G + +S RY+DVFNPA G VAQVAL ++ EVD V + AAFPAW+ T P Sbjct: 5 QINHFISGTQATGRSERYSDVFNPATGAVVAQVALASTQEVDKVVASACAAFPAWAETSP 64 Query: 63 LTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLKGE 122 L RAR++F+F L++Q D +A +I REHGK FSDA+GEV RGIE+VEFA GIP +LK Sbjct: 65 LRRARIMFKFKELLEQHHDQLAALITREHGKVFSDAKGEVVRGIEVVEFACGIPHLLKTS 124 Query: 123 YTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPSAS 182 +TD I GID W++RQ LGVVAGITPFNFP MVPMWMFP+AIACGNCF+LKPSERDPSAS Sbjct: 125 HTDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVAIACGNCFILKPSERDPSAS 184 Query: 183 LLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAKGK 242 LLIADLLK+AGLPDGVFNV+QGDK VDALL HP V+A+SFVGSTPIAEYIY G+ +GK Sbjct: 185 LLIADLLKQAGLPDGVFNVVQGDKTAVDALLAHPDVQALSFVGSTPIAEYIYTEGARRGK 244 Query: 243 RVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAALA 302 RVQALGGAKNH+VVMPDAD++ AVDAL+GAAYGSAGERCMAISVAVAVG D LV LA Sbjct: 245 RVQALGGAKNHLVVMPDADLEQAVDALIGAAYGSAGERCMAISVAVAVGDVADRLVQQLA 304 Query: 303 ERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEKGF 362 +RA LKI G A +EMGP+VT K ++E + +GVEEGA L+VDGRG V G E GF Sbjct: 305 QRAAALKIGNGDQADSEMGPLVTGVHKAKVEAYVAKGVEEGAKLLVDGRGISVAGHENGF 364 Query: 363 FVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGGVA 422 FVGGTL DHVTPEMT+YKEEIFGPVL V+R PD+ASAVEL+NAHE+GNGV+++T DGGVA Sbjct: 365 FVGGTLFDHVTPEMTIYKEEIFGPVLSVVRVPDLASAVELVNAHEFGNGVSLFTSDGGVA 424 Query: 423 REFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQRWP 482 R F RQI+VGMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EG+RFYTR K++MQRWP Sbjct: 425 RAFSRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGIRFYTRYKSIMQRWP 484 Query: 483 NTASAGAEFAFPQMK 497 ++ + GAEF P K Sbjct: 485 DSIAKGAEFTMPVAK 499 >ref|YP_004687388.1| methylmalonate-semialdehyde dehydrogenase MmsA [Cupriavidus necator N-1] gb|AEI78907.1| methylmalonate-semialdehyde dehydrogenase MmsA [Cupriavidus necator N-1] Length = 659 Score = 719 bits (1856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/494 (70%), Positives = 403/494 (81%) Query: 4 IAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNTPPL 63 I H I G++ S R AD++NPA G A+VALGT+ +V AV A AAFPAW++TPPL Sbjct: 166 IGHSIAGRQTRGASQRLADIYNPATGEVAARVALGTTQDVADAVAAAQAAFPAWADTPPL 225 Query: 64 TRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLKGEY 123 RAR+LF+F L+ Q DD+A +I REHGK FSDA+GEV RGIE+VEFA GIP +LK ++ Sbjct: 226 RRARILFKFKELLDQHHDDLAALITREHGKVFSDAKGEVTRGIEVVEFACGIPNLLKTDF 285 Query: 124 TDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPSASL 183 TD I GID W++RQ LGVVAGITPFNFP MVPMWMFP+AIACGN FVLKPSERDPS SL Sbjct: 286 TDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVAIACGNTFVLKPSERDPSPSL 345 Query: 184 LIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAKGKR 243 LIADLL++AGLPDGVFNV+QGDK VDALL HP V+A+SFVGSTPIAEYIY G+ GKR Sbjct: 346 LIADLLRQAGLPDGVFNVVQGDKEAVDALLAHPDVQALSFVGSTPIAEYIYTEGTKHGKR 405 Query: 244 VQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAALAE 303 VQALGGAKNH+VVMPDAD+ AVDAL+GAAYGSAGERCMAISVAVAVG D+LV LAE Sbjct: 406 VQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGDVADKLVPRLAE 465 Query: 304 RAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEKGFF 363 RA LKI GM + AEMGP+VTAA K ++EG I +GVEEGATLV DGRG+ VPG E GF+ Sbjct: 466 RASSLKIRNGMESDAEMGPLVTAAHKAKVEGYIAKGVEEGATLVTDGRGHTVPGHENGFY 525 Query: 364 VGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGGVAR 423 VGGTL D+V P+MT+YKEEIFGPVL V+R D A AV LINAHE+GNGV+ YT DGG+AR Sbjct: 526 VGGTLFDNVKPDMTIYKEEIFGPVLSVVRVHDFAEAVALINAHEFGNGVSCYTSDGGIAR 585 Query: 424 EFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQRWPN 483 F RQI++GMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EGVRFYTR K+VMQRWP+ Sbjct: 586 AFARQIQIGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRYKSVMQRWPD 645 Query: 484 TASAGAEFAFPQMK 497 + + GAEF P K Sbjct: 646 SIAKGAEFTMPVAK 659 >ref|YP_004684127.1| methylmalonate-semialdehyde dehydrogenase MmsA [Cupriavidus necator N-1] gb|AEI75646.1| methylmalonate-semialdehyde dehydrogenase MmsA [Cupriavidus necator N-1] Length = 505 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/497 (70%), Positives = 404/497 (81%) Query: 1 MEKIAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNT 60 + +I H+IGG R+ADVFNPA G A+VALGT+ +V AV A AAFPAW++T Sbjct: 9 LAEIHHFIGGAVRRAGGQRHADVFNPATGEVAARVALGTTQDVADAVAAAQAAFPAWADT 68 Query: 61 PPLTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLK 120 PPL RAR+LF+F L+ Q DD+A +I REHGK FSDA+GEV RGIE+VEFA GIP +LK Sbjct: 69 PPLRRARILFKFKELLDQHHDDLAALITREHGKVFSDAKGEVTRGIEVVEFACGIPNLLK 128 Query: 121 GEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPS 180 ++TD I GID W++RQ LGVVAGITPFNFP MVPMWMFP+AIACGN FVLKPSERDPS Sbjct: 129 TDFTDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVAIACGNTFVLKPSERDPS 188 Query: 181 ASLLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAK 240 SLLIADLL++AGLPDGVFNV+QGDK VDALL HP V+A+SFVGSTPIAEYIY G+ Sbjct: 189 PSLLIADLLRQAGLPDGVFNVVQGDKEAVDALLAHPDVQALSFVGSTPIAEYIYTEGTKH 248 Query: 241 GKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAA 300 GKRVQALGGAKNH+VVMPDAD+ AVDAL+GAAYGSAGERCMAISVAVAVG D+LV Sbjct: 249 GKRVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGDVADKLVPR 308 Query: 301 LAERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEK 360 LAERA LKI GM + AEMGP+VT A K ++EG I +GV+EGATLV DGRG++V G E Sbjct: 309 LAERARTLKIRNGMESDAEMGPLVTGAHKAKVEGYIAKGVQEGATLVTDGRGHKVDGHEN 368 Query: 361 GFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGG 420 GF+VGGTL D+V P+MT+YKEEIFGPVL V+R D A AV LINAHEYGNGV+ YT DGG Sbjct: 369 GFYVGGTLFDNVKPDMTIYKEEIFGPVLSVVRVHDFAEAVSLINAHEYGNGVSCYTSDGG 428 Query: 421 VAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQR 480 +AR F RQI+VGMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EGVRFYTR K+VMQR Sbjct: 429 IARAFARQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRYKSVMQR 488 Query: 481 WPNTASAGAEFAFPQMK 497 WP++ + GAEF P K Sbjct: 489 WPDSIAKGAEFTMPVAK 505 >ref|YP_294475.1| methylmalonate-semialdehyde dehydrogenase [acylating] [Ralstonia eutropha JMP134] gb|AAZ59631.1| methylmalonate-semialdehyde dehydrogenase (acylating) [Ralstonia eutropha JMP134] Length = 505 Score = 712 bits (1837), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/495 (71%), Positives = 404/495 (81%) Query: 3 KIAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNTPP 62 +I HYIGG S R+ADVFNPA G A+VALGT+ EV AV A AAFPAW++TPP Sbjct: 11 EIHHYIGGTVRPGASARFADVFNPATGEVAARVALGTAQEVSDAVAAAKAAFPAWADTPP 70 Query: 63 LTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLKGE 122 L RAR+LF+F L+ + DD+A +I REHGK FSDA+GEV RG+EIVEFA GIP +LK + Sbjct: 71 LRRARILFKFKELLDKHHDDLAALITREHGKVFSDAKGEVTRGVEIVEFACGIPNLLKTD 130 Query: 123 YTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPSAS 182 +TD + GID W++RQ LGVVAGITPFNFP MVPMWMFP+A+ACGN FVLKPSERDPS S Sbjct: 131 FTDNVGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERDPSPS 190 Query: 183 LLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAKGK 242 LLIADLLK+AGLPDGVFNV+QGDKV VDALL +P V+A+SFVGSTPIAEYIY G+ GK Sbjct: 191 LLIADLLKQAGLPDGVFNVVQGDKVAVDALLANPDVQALSFVGSTPIAEYIYTEGTKHGK 250 Query: 243 RVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAALA 302 RVQALGGAKNH+VVMPDAD+ AVDAL+GA YGSAGERCMAISVAVAVG D+LV LA Sbjct: 251 RVQALGGAKNHLVVMPDADLDQAVDALIGAGYGSAGERCMAISVAVAVGDVADKLVPRLA 310 Query: 303 ERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEKGF 362 ERA LKI GM A AEMGP+VT A K ++EG I +GVEEGATLV DGRG++V G E GF Sbjct: 311 ERAAALKIRNGMEADAEMGPLVTGAHKAKVEGYIAKGVEEGATLVTDGRGHKVEGHENGF 370 Query: 363 FVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGGVA 422 +VGGTL DHVTP+MT+YKEEIFGPVL V+R D A AV LINAHEYGNGV+ YT DGG+A Sbjct: 371 YVGGTLFDHVTPDMTIYKEEIFGPVLSVVRVHDFAEAVALINAHEYGNGVSCYTSDGGIA 430 Query: 423 REFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQRWP 482 R F RQI++GMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EGVRFYTR K+VMQRWP Sbjct: 431 RAFARQIQIGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRYKSVMQRWP 490 Query: 483 NTASAGAEFAFPQMK 497 ++ GAEF P K Sbjct: 491 DSIGKGAEFMMPVAK 505 >ref|YP_728089.1| methylmalonate-semialdehyde dehydrogenase [Ralstonia eutropha H16] emb|CAJ94721.1| Methylmalonate-semialdehyde dehydrogenase [Ralstonia eutropha H16] Length = 508 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/494 (70%), Positives = 403/494 (81%) Query: 4 IAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNTPPL 63 I H I G++ S R AD++NPA G A+VALGT+ +V AV A AAFPAW++TPPL Sbjct: 15 IGHSIAGRQTRGASQRLADIYNPATGEVAARVALGTTQDVADAVAAAHAAFPAWADTPPL 74 Query: 64 TRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLKGEY 123 RAR+LF+F L+ Q DD+A +I REHGK FSDA+GEV RGIE+VEFA GIP +LK ++ Sbjct: 75 RRARILFKFKELLDQHHDDLAALITREHGKVFSDARGEVTRGIEVVEFACGIPSLLKTDF 134 Query: 124 TDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPSASL 183 TD I GID W++RQ LGVVAGITPFNFP MVPMWMFP+A+ACGN FVLKPSERDPS SL Sbjct: 135 TDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERDPSPSL 194 Query: 184 LIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAKGKR 243 LIADLL++AGLPDGVFNV+QGDK VDALL HP V+A+SFVGSTPIAEYIY G+ GKR Sbjct: 195 LIADLLRQAGLPDGVFNVVQGDKEAVDALLAHPDVQALSFVGSTPIAEYIYTEGTKHGKR 254 Query: 244 VQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAALAE 303 VQALGGAKNH+VVMPDAD+ AVDAL+GAAYGSAGERCMAISVAVAVG D+LV LAE Sbjct: 255 VQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGDVADKLVPRLAE 314 Query: 304 RAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEKGFF 363 RA LKI GM + AEMGP+VTAA K ++EG I +GVEEGATLV DGRG+ VPG E GF+ Sbjct: 315 RASSLKIRNGMESDAEMGPLVTAAHKAKVEGYIAKGVEEGATLVTDGRGHTVPGHENGFY 374 Query: 364 VGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGGVAR 423 VGGTL DHV P+MT+YKEEIFGPVL V+R D A AV LINAHE+GNGV+ YT DGG+AR Sbjct: 375 VGGTLFDHVKPDMTIYKEEIFGPVLSVVRVHDFAEAVALINAHEFGNGVSCYTSDGGIAR 434 Query: 424 EFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQRWPN 483 F RQI++GMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EGVRFYTR K+VMQRWP+ Sbjct: 435 AFARQIQIGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRYKSVMQRWPD 494 Query: 484 TASAGAEFAFPQMK 497 + + GAEF P K Sbjct: 495 SIAKGAEFTMPVAK 508 >ref|YP_724792.1| methylmalonate-semialdehyde dehydrogenase [Ralstonia eutropha H16] emb|CAJ91424.1| Methylmalonate-semialdehyde dehydrogenase [Ralstonia eutropha H16] Length = 505 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/497 (70%), Positives = 403/497 (81%) Query: 1 MEKIAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNT 60 + +I H+IGG R ADVFNPA G A+VALGT+ +V AV A AAFPAW++T Sbjct: 9 LAEIHHFIGGAVRRAGGQRLADVFNPATGEVAARVALGTTQDVADAVAAAHAAFPAWADT 68 Query: 61 PPLTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLK 120 PPL RAR+LF+F L+ Q DD+A +I REHGK FSDA+GEV RGIE+VEFA GIP +LK Sbjct: 69 PPLRRARILFKFKELLDQHHDDLAALITREHGKVFSDARGEVTRGIEVVEFACGIPNLLK 128 Query: 121 GEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPS 180 ++TD I GID W++RQ LGVVAGITPFNFP MVPMWMFP+A+ACGN FVLKPSERDPS Sbjct: 129 TDFTDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVALACGNTFVLKPSERDPS 188 Query: 181 ASLLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAK 240 SLLIADLL++AGLPDGVFNV+QGDK VDALL HP V+A+SFVGSTPIAEYIY G+ Sbjct: 189 PSLLIADLLRQAGLPDGVFNVVQGDKEAVDALLAHPDVQALSFVGSTPIAEYIYTEGTKH 248 Query: 241 GKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAA 300 GKRVQALGGAKNH+VVMPDAD+ AVDAL+GAAYGSAGERCMAISVAVAVG D+LV Sbjct: 249 GKRVQALGGAKNHLVVMPDADLDQAVDALIGAAYGSAGERCMAISVAVAVGDVADKLVPR 308 Query: 301 LAERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEK 360 LAERA LKI GM + AEMGP+VTAA K ++EG I +GVEEGA LV DGRG+ VPG E Sbjct: 309 LAERASSLKIRNGMESDAEMGPLVTAAHKAKVEGYIAKGVEEGAMLVTDGRGHTVPGHEN 368 Query: 361 GFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGG 420 GF+VGGTL DHV P+MT+YKEEIFGPVL V+R D A AV LINAHEYGNGV+ YT DGG Sbjct: 369 GFYVGGTLFDHVKPDMTIYKEEIFGPVLSVVRVHDFAEAVALINAHEYGNGVSCYTSDGG 428 Query: 421 VAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQR 480 +AR F RQI+VGMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EGVRFYTR K+VMQR Sbjct: 429 IARAFARQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRYKSVMQR 488 Query: 481 WPNTASAGAEFAFPQMK 497 WP++ + GAEF P K Sbjct: 489 WPDSIAKGAEFTMPVAK 505 >ref|ZP_07673516.1| methylmalonate-semialdehyde dehydrogenase (acylating) [Ralstonia sp. 5_7_47FAA] gb|EFP68075.1| methylmalonate-semialdehyde dehydrogenase (acylating) [Ralstonia sp. 5_7_47FAA] Length = 507 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/494 (70%), Positives = 397/494 (80%) Query: 4 IAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNTPPL 63 ++HYIGGQR R ADVFNPA G AQV LG EVDAAV A AA P W+ T PL Sbjct: 14 VSHYIGGQRHAGSGTRSADVFNPATGAVSAQVLLGGKSEVDAAVAAAHAAAPDWAETSPL 73 Query: 64 TRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLKGEY 123 R+RVLF+F L+ Q D +A I REHGK FSDA+GEV RGIE+VEFA GIP +LK E+ Sbjct: 74 KRSRVLFKFKELLDQNHDALAAAITREHGKVFSDAKGEVTRGIEVVEFACGIPNLLKTEF 133 Query: 124 TDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPSASL 183 TD I GID W++RQ LGVVAGITPFNFP MVPMWM P+A+ACGN F+LKPSERDP+ SL Sbjct: 134 TDNIGGGIDNWNLRQPLGVVAGITPFNFPFMVPMWMAPVALACGNTFILKPSERDPTPSL 193 Query: 184 LIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAKGKR 243 +IADLLK+AGLPDGVFNV+QG K VDALL+HP V+AISFVGSTPIAEYIYA G+ +GKR Sbjct: 194 MIADLLKQAGLPDGVFNVVQGGKDAVDALLEHPNVQAISFVGSTPIAEYIYAEGTKRGKR 253 Query: 244 VQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAALAE 303 VQALGGAKNH+VVMPDAD+ AVDAL+GA YGSAGERCMAISVAVAVG D+LV LAE Sbjct: 254 VQALGGAKNHLVVMPDADLDQAVDALIGAGYGSAGERCMAISVAVAVGDVADKLVPRLAE 313 Query: 304 RAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEKGFF 363 RA LKI GM A +EMGP+VTAA K ++EG I +GVEEGA LVVDGRG+ V G +GFF Sbjct: 314 RARALKIGNGMQADSEMGPLVTAAHKAKVEGYIAKGVEEGAELVVDGRGHTVDGHAEGFF 373 Query: 364 VGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGGVAR 423 GGTL DHV P MT+YKEEIFGPVL V+R D+A AV+LINAHE+GNGV+ YT DGGVAR Sbjct: 374 TGGTLFDHVKPGMTIYKEEIFGPVLSVVRVHDLAEAVDLINAHEFGNGVSCYTSDGGVAR 433 Query: 424 EFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQRWPN 483 F RQI+VGMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EGVRFYTR K+VMQRWP+ Sbjct: 434 AFARQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGVRFYTRYKSVMQRWPD 493 Query: 484 TASAGAEFAFPQMK 497 + + GAEF P K Sbjct: 494 SIAKGAEFVMPTAK 507 >ref|YP_002290472.1| methylmalonate-semialdehyde dehydrogenase [Oligotropha carboxidovorans OM5] ref|YP_004631597.1| methylmalonate semialdehyde dehydrogenase IolA [Oligotropha carboxidovorans OM5] gb|ACI94607.1| methylmalonate-semialdehyde dehydrogenase [Oligotropha carboxidovorans OM5] gb|AEI01781.1| methylmalonate semialdehyde dehydrogenase IolA [Oligotropha carboxidovorans OM4] gb|AEI05356.1| methylmalonate semialdehyde dehydrogenase IolA [Oligotropha carboxidovorans OM5] Length = 505 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/497 (69%), Positives = 405/497 (81%) Query: 1 MEKIAHYIGGQRVDTKSGRYADVFNPAQGVPVAQVALGTSDEVDAAVRAGVAAFPAWSNT 60 + I+H+I G+ SGR +DVFNPA G A+V+LG++ +VDAAV A AAFP WS T Sbjct: 9 VNTISHWINGKPFAATSGRTSDVFNPAIGAVSARVSLGSAADVDAAVDAAKAAFPEWSET 68 Query: 61 PPLTRARVLFRFLHLIQQRADDIARIIVREHGKTFSDAQGEVARGIEIVEFAAGIPQMLK 120 PPL RAR+LF+F L+ + D +A +I REHGK FSDA+GEV RGIE+VEFA GIP +LK Sbjct: 69 PPLRRARILFKFKELLDRNHDKLAELITREHGKVFSDAKGEVIRGIEVVEFACGIPTLLK 128 Query: 121 GEYTDQIARGIDAWSMRQALGVVAGITPFNFPAMVPMWMFPIAIACGNCFVLKPSERDPS 180 E+TD I GID W++RQ LGVVAGITPFNFP MVPMWM P+A+ACGN FVLKPSERDPS Sbjct: 129 SEFTDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMVPVALACGNTFVLKPSERDPS 188 Query: 181 ASLLIADLLKEAGLPDGVFNVLQGDKVTVDALLDHPQVKAISFVGSTPIAEYIYARGSAK 240 SLLIA+LLKEAGLPDGVFNV+QGDK+ VD LL+HP V+A+SFVGSTPIAEYIY G+++ Sbjct: 189 PSLLIAELLKEAGLPDGVFNVVQGDKIAVDTLLEHPDVEALSFVGSTPIAEYIYKEGTSR 248 Query: 241 GKRVQALGGAKNHMVVMPDADMQLAVDALMGAAYGSAGERCMAISVAVAVGSAGDELVAA 300 GKRVQALGGAKNH+VVMPDA++ VDAL+GAAYGSAGERCMAISVAV VG DELV Sbjct: 249 GKRVQALGGAKNHLVVMPDANLDQVVDALIGAAYGSAGERCMAISVAVTVGDVADELVPR 308 Query: 301 LAERAGKLKINEGMAAGAEMGPVVTAAAKERIEGLIGRGVEEGATLVVDGRGYQVPGFEK 360 LAERA LKI GM + AEMGP+VT+ + ++EG I +G EGATLVVDGRG++V G EK Sbjct: 309 LAERARTLKIRNGMDSEAEMGPLVTSIHQAKVEGYIAKGQGEGATLVVDGRGHEVEGHEK 368 Query: 361 GFFVGGTLLDHVTPEMTVYKEEIFGPVLCVLRCPDIASAVELINAHEYGNGVAVYTRDGG 420 GF+VGGTL DHVTP MT+YK+EIFGPVL V+R D+A AVELINAHE+GNGV+ YT DGG Sbjct: 369 GFYVGGTLFDHVTPNMTIYKDEIFGPVLSVVRVRDLAEAVELINAHEFGNGVSCYTSDGG 428 Query: 421 VAREFVRQIEVGMVGVNVPLPVPMAFSSFGGWKRSLFGDHHMYGPEGVRFYTRAKAVMQR 480 VAR F RQI+VGMVG+NVP+PVPMA+ SFGGWKRSLFGDHH YG EG+RFYTR K++MQR Sbjct: 429 VARAFSRQIKVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGIRFYTRYKSIMQR 488 Query: 481 WPNTASAGAEFAFPQMK 497 WP++ GAEF P K Sbjct: 489 WPSSIGKGAEFTMPVAK 505