BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0123.p (1073 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777808.1| cobalt-zinc-cadmium resistance cation efflux... 2147 0.0 ref|YP_004753172.1| RND divalent metal cation efflux transporter... 1714 0.0 ref|ZP_07673472.1| cobalt-zinc-cadmium resistance protein CzcA [... 1698 0.0 ref|YP_001353482.1| CzcA family heavy metal efflux protein [Jant... 1697 0.0 ref|YP_003846726.1| heavy metal efflux pump, CzcA family [Gallio... 1688 0.0 ref|YP_001099897.1| RND divalent metal cation efflux transporter... 1676 0.0 ref|YP_004682537.1| cation efflux system protein CzcA [Cupriavid... 1673 0.0 ref|YP_841919.1| cation/multidrug efflux pump [Ralstonia eutroph... 1665 0.0 ref|YP_001899332.1| CzcA family heavy metal efflux pump [Ralston... 1664 0.0 ref|YP_145595.1| cation efflux system transmembrane protein [Ral... 1659 0.0 >ref|YP_003777808.1| cobalt-zinc-cadmium resistance cation efflux system transmembrane protein [Herbaspirillum seropedicae SmR1] gb|ADJ65900.1| cobalt-zinc-cadmium resistance cation efflux system transmembrane protein [Herbaspirillum seropedicae SmR1] Length = 1073 Score = 2147 bits (5564), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1065/1073 (99%), Positives = 1069/1073 (99%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE Sbjct: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQ ARSQ Sbjct: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQLARSQ 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIK QLRLVPG Sbjct: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKPQLRLVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA Sbjct: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE Sbjct: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV Sbjct: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR Sbjct: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM Sbjct: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV Sbjct: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK Sbjct: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSRE+LLEAIQDEVAKIP Sbjct: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREELLEAIQDEVAKIP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTA KISAVLEKIPGATEVKIE Sbjct: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTASKISAVLEKIPGATEVKIE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA Sbjct: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 Query: 781 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG 840 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG Sbjct: 781 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG 840 Query: 841 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM 900 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM Sbjct: 841 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM 900 Query: 901 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS 960 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS Sbjct: 901 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS 960 Query: 961 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1020 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL Sbjct: 961 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1020 Query: 1021 SSTALTLLVLPLLYKLAHDKDEEDNPAGPLSRPPFWKFWLRQSSTVKGNHHGY 1073 SSTALTLLVLPLLYKLAHDKDEEDNPAGP SRPPFWKFW++QSST+KGNHHGY Sbjct: 1021 SSTALTLLVLPLLYKLAHDKDEEDNPAGPPSRPPFWKFWVKQSSTLKGNHHGY 1073 >ref|YP_004753172.1| RND divalent metal cation efflux transporter [Collimonas fungivorans Ter331] gb|AEK62349.1| RND divalent metal cation efflux transporter [Collimonas fungivorans Ter331] Length = 1057 Score = 1714 bits (4440), Expect = 0.0, Method: Compositional matrix adjust. Identities = 843/1045 (80%), Positives = 947/1045 (90%), Gaps = 1/1045 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFERIIRFAIE RWLV+LAV M A G+Y+YQKLPIDAVPDITNVQVQINTSAPGYSPLE Sbjct: 1 MFERIIRFAIEQRWLVMLAVFAMAALGIYNYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQR+++PIET+MSGLP+L+Q RSLSRYGLSQVTVIFKDGTDIYFARQ+VNERIQ+AR + Sbjct: 61 TEQRVTFPIETVMSGLPHLQQTRSLSRYGLSQVTVIFKDGTDIYFARQMVNERIQEARGK 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP G+ P MGPIS+GLGEIYLWTVE++D A+K DG+ YTATDLREIQDW+IK QLR V G Sbjct: 121 LPAGVTPAMGPISSGLGEIYLWTVEAKDGAKKADGSAYTATDLREIQDWIIKPQLRNVSG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEIN+IGGFAKEY VAP EKLASYG+T+ I+ AL++NNSNVGAGYIE+RGEQ LIRA Sbjct: 181 VTEINSIGGFAKEYQVAPVPEKLASYGLTLQDIVTALDRNNSNVGAGYIEKRGEQLLIRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQV SI+D+ NI+L NV+GVPIRIRD+ EV IGRELRTGAATENGREVVLGTVFMLIGE Sbjct: 241 PGQVQSIEDMRNIILGNVQGVPIRIRDIGEVAIGRELRTGAATENGREVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQAV RKM +INRSLP GVEAVTVYDRTVLVDKAI TVKKNL+EGA+LV+A+LF+ Sbjct: 301 NSRAVSQAVDRKMVDINRSLPPGVEAVTVYDRTVLVDKAINTVKKNLLEGAILVIAILFM 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGNIRAAIITAMVIPL+MLFTFTGMV KVSANLLSLGALDFGIIIDGAVVIVENCVRR Sbjct: 361 FLGNIRAAIITAMVIPLSMLFTFTGMVQYKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQAHHGR LTRSERFHEVFAA+KEARRPL+FGQ+IIM+VYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQAHHGRPLTRSERFHEVFAASKEARRPLLFGQVIIMVVYLPIFALTGVEGKMFNPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 A TVV AL+GAMILS+TFIPAA+ALFIG++VAE EN LM AKR Y P+L+ +M K +V Sbjct: 481 ALTVVIALVGAMILSITFIPAAVALFIGKRVAETENFLMRGAKRFYAPVLEWVMLRKAMV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 L A ++L+ G++A+RLGSEFVPSLNEGDMAIQALRIPGTSL+QSLEMQKQIE TLK++ Sbjct: 541 LGGALVVLLLSGLLATRLGSEFVPSLNEGDMAIQALRIPGTSLTQSLEMQKQIESTLKRQ 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPE+ERVFARTGTAE+ASDPMPPNISDGYIMLKP+ WP+PKKSR +LL AIQ+ KIP Sbjct: 601 FPEIERVFARTGTAEIASDPMPPNISDGYIMLKPETDWPKPKKSRPELLAAIQEAANKIP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSD+AVK+FGDDM VLNDTA K+S VL KI GA EVKIE Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDIAVKIFGDDMAVLNDTADKVSTVLGKISGAAEVKIE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QT+GLPMLTV IDR+KTARYGLNV+D+QD VATAIGGKEAGT+FQGDRRF IVVRLP++ Sbjct: 721 QTSGLPMLTVNIDRDKTARYGLNVADVQDVVATAIGGKEAGTLFQGDRRFDIVVRLPEEL 780 Query: 781 RTDLEAIRRLPIALPPQEGAT-RVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVR 839 R+DLEA RRLPI+LP G R +Y+PL EVASL +APGPNQISRE+GKRRIVVSANVR Sbjct: 781 RSDLEAFRRLPISLPRSAGGEGRTNYIPLSEVASLELAPGPNQISRENGKRRIVVSANVR 840 Query: 840 GRDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFA 899 GRD+G FVAE E +LQ VK+P+GYWT+WGGQFE LQSA+QRLQIVIPVALL+VF LLFA Sbjct: 841 GRDIGSFVAETEAKLQQQVKIPSGYWTSWGGQFEQLQSASQRLQIVIPVALLLVFTLLFA 900 Query: 900 MFSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIR 959 MF N+KDGLLVF+GIPFALTGGI+AL +RGIP+SISAAVGFIAL GVAVLNGLVMI+FIR Sbjct: 901 MFGNIKDGLLVFSGIPFALTGGIVALWLRGIPLSISAAVGFIALCGVAVLNGLVMIAFIR 960 Query: 960 SLREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGI 1019 SLREEGR LDAAI EGA+TRLRPVLMTALVASLGFVPMA+ATGTGAEVQRPLATVVIGGI Sbjct: 961 SLREEGRGLDAAIREGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGI 1020 Query: 1020 LSSTALTLLVLPLLYKLAHDKDEED 1044 LSST LTLLVLP+LY+L H +DE++ Sbjct: 1021 LSSTILTLLVLPILYQLFHRRDEDE 1045 >ref|ZP_07673472.1| cobalt-zinc-cadmium resistance protein CzcA [Ralstonia sp. 5_7_47FAA] gb|EFP68171.1| cobalt-zinc-cadmium resistance protein CzcA [Ralstonia sp. 5_7_47FAA] Length = 1058 Score = 1698 bits (4397), Expect = 0.0, Method: Compositional matrix adjust. Identities = 838/1046 (80%), Positives = 944/1046 (90%), Gaps = 1/1046 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFERIIRFAIE RWL++LAVLGM A GVY+Y KLPIDAVPDITNVQVQINT+APGYSPLE Sbjct: 1 MFERIIRFAIEQRWLIILAVLGMAALGVYNYGKLPIDAVPDITNVQVQINTAAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQRI+YPIET+M+GLP LEQ RSLSRYGLSQVTVIFKDGTDIYFARQLVN+RIQ+A+ + Sbjct: 61 TEQRITYPIETVMAGLPGLEQTRSLSRYGLSQVTVIFKDGTDIYFARQLVNQRIQEAKER 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP G+ P MGPISTGLGEIYLWTVE+ D ARKPDG YT TDLREIQDWV+K QLR V G Sbjct: 121 LPGGVTPAMGPISTGLGEIYLWTVEAEDGARKPDGAAYTPTDLREIQDWVVKPQLRNVTG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEIN+IGG+AKEYLVAPS E+LASYG+T+ ++ AL+KNNSNVGAGYIERRGEQYL+RA Sbjct: 181 VTEINSIGGYAKEYLVAPSLERLASYGLTLTDLVSALDKNNSNVGAGYIERRGEQYLVRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQV S+DDI ++++ +G PIRIRDVA+V+IGRELRTGAATENG+EVVLGTVFMLIGE Sbjct: 241 PGQVKSLDDIRDVIVGTAQGQPIRIRDVADVDIGRELRTGAATENGKEVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQAV +KM EINR+LP GV+AVTVYDRTVLVDKAIATVKKNL+EGA LV+A+LF+ Sbjct: 301 NSRAVSQAVDKKMAEINRTLPAGVKAVTVYDRTVLVDKAIATVKKNLLEGATLVIAILFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGNIRAA+ITAMVIPLAMLFTFTGMVS K+SANL+SLGALDFGIIIDGAVVIVENCVRR Sbjct: 361 FLGNIRAAVITAMVIPLAMLFTFTGMVSYKISANLMSLGALDFGIIIDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQ HH R LTRSERFHEVFAAA+EARRPL+FGQLIIMIVYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQEHHKRELTRSERFHEVFAAAREARRPLLFGQLIIMIVYLPIFALTGVEGKMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+ AM+LS+TF+PAA+ALFIG KVAEKEN LM WAK Y+PML+ + N PVV Sbjct: 481 AFTVVLALLAAMVLSMTFVPAAVALFIGRKVAEKENRLMEWAKHRYQPMLEASLANTPVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFA I+ C VASRLGSEFVP+LNEGD+AIQ+LRIPGTSLSQSLEMQKQ+E TLK K Sbjct: 541 LTFACIAIVFCLAVASRLGSEFVPNLNEGDIAIQSLRIPGTSLSQSLEMQKQVESTLKAK 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPE+ER+FARTGTAE+ASDPMPPNISDGYIMLKPQ QWP+PKK++E+LL AIQ E +IP Sbjct: 601 FPEIERIFARTGTAEIASDPMPPNISDGYIMLKPQAQWPKPKKTKEELLSAIQAEAERIP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSDVA+K+FGDD VLN+TAGK++AVL+ I GATEVKIE Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDVAIKIFGDDNDVLNETAGKVAAVLQGIQGATEVKIE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPML+V IDR+K ARYGLN+SD+QD VA AIGGKEAGT FQGDRRF I+VRLPD Sbjct: 721 QTTGLPMLSVNIDRQKAARYGLNMSDVQDAVAIAIGGKEAGTFFQGDRRFYILVRLPDAV 780 Query: 781 RTDLEAIRRLPIALPPQ-EGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVR 839 R DLEA+RRLP+ LP G ++ +Y+PL EVASL +APGPNQ+SRE+GKRRIV+SANVR Sbjct: 781 RGDLEALRRLPVPLPKNGAGESKTTYIPLSEVASLDLAPGPNQVSRENGKRRIVISANVR 840 Query: 840 GRDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFA 899 GRD+G FV EAE ++ VK+P GYW TWGG FE LQSAT RLQIV+PVALL+VFVLLFA Sbjct: 841 GRDIGSFVPEAEAAIERQVKIPTGYWITWGGTFEQLQSATTRLQIVVPVALLLVFVLLFA 900 Query: 900 MFSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIR 959 MF+NVKDGLLVFTGIPFALTGGILAL +RGIP+SISAAVGFIALSGVAVLNGLVM+SFIR Sbjct: 901 MFNNVKDGLLVFTGIPFALTGGILALWLRGIPLSISAAVGFIALSGVAVLNGLVMLSFIR 960 Query: 960 SLREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGI 1019 SLREEG++LD AI GA+TRLRPVLMTALVASLGFVPMA+ATGTGAEVQRPLATVVIGGI Sbjct: 961 SLREEGQSLDTAIRTGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGI 1020 Query: 1020 LSSTALTLLVLPLLYKLAHDKDEEDN 1045 LSSTALTLLVLP+LY+LAH KDE ++ Sbjct: 1021 LSSTALTLLVLPVLYRLAHRKDEAED 1046 >ref|YP_001353482.1| CzcA family heavy metal efflux protein [Janthinobacterium sp. Marseille] gb|ABR89736.1| heavy metal efflux pump, CzcA family [Janthinobacterium sp. Marseille] Length = 1051 Score = 1697 bits (4396), Expect = 0.0, Method: Compositional matrix adjust. Identities = 829/1044 (79%), Positives = 948/1044 (90%), Gaps = 1/1044 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFER+I FAI RWLV+LAV GM A+G+Y+YQKLPIDAVPDITNVQVQINT+APGYSPLE Sbjct: 1 MFERLISFAIAQRWLVMLAVSGMAAFGIYNYQKLPIDAVPDITNVQVQINTAAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQRI+YPIET+M+GLP+LEQ RSLSRYGLSQ+TVIFKDGTDIYFARQ+++ERIQ+AR Sbjct: 61 TEQRITYPIETVMAGLPHLEQTRSLSRYGLSQITVIFKDGTDIYFARQMISERIQEARQN 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LPPGI P MGPISTGLGEIYLWTVE+++ A+KPDG+ YT TDLREIQDW+IK QLR VPG Sbjct: 121 LPPGITPAMGPISTGLGEIYLWTVEAKEGAKKPDGSAYTPTDLREIQDWIIKPQLRNVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEINTIGGFAKEY VAP AE+LASYG+ + I+ ALE+NN NVGAGYIE+RGEQ LIRA Sbjct: 181 VTEINTIGGFAKEYQVAPVAERLASYGLNLQDIVTALERNNGNVGAGYIEKRGEQLLIRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQV SI DIGNI+L NV+GVPIRIRDV EV+IGRELRTGAATENGREVVLGTVFMLIG+ Sbjct: 241 PGQVQSIADIGNIILGNVQGVPIRIRDVGEVQIGRELRTGAATENGREVVLGTVFMLIGQ 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQAV +KM EINRSLP+GV+AVTVYDRTVLVDKAI TVKKNL+EGA+LV+ VLF+ Sbjct: 301 NSRTVSQAVDKKMVEINRSLPEGVQAVTVYDRTVLVDKAINTVKKNLLEGAVLVIVVLFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGN RAA+ITAMVIPL+MLFTF+GMV+ KVSANL+SLGALDFGII+DGAVVIVENCVRR Sbjct: 361 FLGNFRAALITAMVIPLSMLFTFSGMVTYKVSANLMSLGALDFGIIVDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQA GR L RSERF EVFAAAKEARRPLIFGQLIIM+VYLP+FAL+GVEG+MF PM Sbjct: 421 LAHAQAGKGRPLNRSERFQEVFAAAKEARRPLIFGQLIIMVVYLPIFALSGVEGRMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAMILS+TFIPAA+ALFIG+KVAEKEN+LM AKR Y P L +M NKPVV Sbjct: 481 AFTVVIALVGAMILSITFIPAAVALFIGDKVAEKENVLMQAAKRWYAPALDYVMANKPVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFA L+L+ G++A+R+GSEFVP+LNEGD+AIQ+LRIPGTSL+QS+EMQKQ+E LKQ Sbjct: 541 LTFAFVLVLLSGLLATRMGSEFVPNLNEGDIAIQSLRIPGTSLTQSVEMQKQLEVALKQA 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 PE+ER+ +RTGTAE+ASDPMPPNISDG +MLKP+ WPEPKKSR++LL+AI+D VAK+P Sbjct: 601 HPEIERIVSRTGTAEIASDPMPPNISDGLVMLKPEADWPEPKKSRDELLQAIRDTVAKLP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSDVAVK+FGDDM+VLNDTA +I+ VL KIPGA EVK+E Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDVAVKLFGDDMEVLNDTAARIATVLGKIPGAAEVKVE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTV IDREKTARYGLNV+D+QDT+ATA GGKEAGT+FQGDRRF I+VRLP+ Sbjct: 721 QTTGLPMLTVNIDREKTARYGLNVADVQDTIATATGGKEAGTLFQGDRRFDILVRLPENV 780 Query: 781 RTDLEAIRRLPIALP-PQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVR 839 R DLEAI+RLP+ LP Q GA R SY+PLGEVA+L +APGPNQ+SRE+GKRRIVVSANVR Sbjct: 781 RNDLEAIKRLPLPLPREQGGAARTSYIPLGEVATLDVAPGPNQVSRENGKRRIVVSANVR 840 Query: 840 GRDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFA 899 GRD+G FV++AE+Q++ VK+PAGYW +WGGQFE LQSAT+RLQ+VIPVAL +VF LLF Sbjct: 841 GRDIGSFVSDAEQQIEQQVKIPAGYWMSWGGQFEQLQSATERLQLVIPVALALVFTLLFV 900 Query: 900 MFSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIR 959 MF N+KDGLLVF+GIPFALTGGI+AL +R IP+SISAAVGFIALSGVAVLNGLVMISFIR Sbjct: 901 MFGNMKDGLLVFSGIPFALTGGIIALWLRDIPISISAAVGFIALSGVAVLNGLVMISFIR 960 Query: 960 SLREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGI 1019 SLREEG L AA+ EGA+TRLRPVLMTALVASLGFVPMA+ATGTGAEVQRPLATVVIGGI Sbjct: 961 SLREEGHALAAAVREGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGI 1020 Query: 1020 LSSTALTLLVLPLLYKLAHDKDEE 1043 LSST LTLLVLPLLY++A+ K+EE Sbjct: 1021 LSSTMLTLLVLPLLYRMAYRKEEE 1044 >ref|YP_003846726.1| heavy metal efflux pump, CzcA family [Gallionella capsiferriformans ES-2] gb|ADL54962.1| heavy metal efflux pump, CzcA family [Gallionella capsiferriformans ES-2] Length = 1060 Score = 1688 bits (4371), Expect = 0.0, Method: Compositional matrix adjust. Identities = 804/1047 (76%), Positives = 953/1047 (91%), Gaps = 3/1047 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFE+IIRFA E RWLVLL V GM A GVY+YQKLPIDAVPDITNVQVQINT+APGYSPLE Sbjct: 1 MFEKIIRFATEQRWLVLLMVFGMAALGVYNYQKLPIDAVPDITNVQVQINTAAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 AEQRI+YPIET+M+GLP L+Q RSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQA+ + Sbjct: 61 AEQRITYPIETVMAGLPGLQQTRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQAKGK 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP G++PGMGPISTGLGEI++WTVE+ + A+K DGTPYT TDLREIQDW+IK QLR VPG Sbjct: 121 LPAGVEPGMGPISTGLGEIFMWTVEAGEGAKKADGTPYTPTDLREIQDWIIKPQLRNVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEINTIGG+AKE+ VAP +KL ++G+T+ ++ A+E+NN+NVGAGYIE+RGEQYLIRA Sbjct: 181 VTEINTIGGYAKEFQVAPLPDKLVAHGLTLQDMVAAIERNNANVGAGYIEKRGEQYLIRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQVA+I+DIGNI++ + +GVPIRIRDVAEV IG+ELRTGAATENGREVVLGTVFMLIGE Sbjct: 241 PGQVATIEDIGNIIVGSRQGVPIRIRDVAEVGIGKELRTGAATENGREVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQAVA+++EEINR+LP+GV A TVYDRT+LVDKAI TVKKNLVEGALLVVA+LF+ Sbjct: 301 NSRTVSQAVAKRLEEINRTLPQGVVAQTVYDRTILVDKAINTVKKNLVEGALLVVAILFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGNIRAAIITA+VIPLAMLFTFTGMVSNKVSANL+SLGALDFGIIIDGAVVIVENCVRR Sbjct: 361 FLGNIRAAIITALVIPLAMLFTFTGMVSNKVSANLMSLGALDFGIIIDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQ+ GR LTR+ERFHEVFAAA+EARRPL++GQLIIM+VYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQSKAGRALTRNERFHEVFAAAREARRPLLYGQLIIMVVYLPIFALTGVEGKMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAMILSV+FIPAA+AL IG+KV+EKE+ LM WAKR Y PML +M NKP+V Sbjct: 481 AFTVVTALLGAMILSVSFIPAAVALLIGDKVSEKESRLMEWAKRGYAPMLNRVMLNKPIV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LT A +++ ++A+R+GSEFVPSLNEGD+A+QALRIPGTSL+Q+LEMQ ++E+T+KQ Sbjct: 541 LTIAAVAVILSALLATRMGSEFVPSLNEGDIALQALRIPGTSLTQALEMQTELERTIKQ- 599 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPEV+R+FA+ GTAE+A+DPMPPN +D ++MLKPQ +WP+PK+S+ L+ A+Q+ V K+P Sbjct: 600 FPEVDRIFAKLGTAEIATDPMPPNAADNFVMLKPQSEWPDPKRSKADLVNAMQEAVTKVP 659 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEF+QPIQ+RFNEL+SGVRSDVAVKVFGDDM +N TAG+I+ VLEK+PGAT VK+E Sbjct: 660 GNNYEFTQPIQMRFNELLSGVRSDVAVKVFGDDMDTMNRTAGEIAEVLEKVPGATAVKVE 719 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLT+ IDREK AR G+NV D+Q+ +A A+GG+EAG +FQGDRRF I+VRLP++ Sbjct: 720 QTTGLPMLTIHIDREKIARLGVNVGDVQEAIAIAVGGREAGVLFQGDRRFNIIVRLPERL 779 Query: 781 RTDLEAIRRLPIALPPQE--GATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANV 838 R+D+EA+++LPI LP E G TR SY+ LG+VA+ +APGPNQISRE+GKRR+VV+ANV Sbjct: 780 RSDMEAMKQLPINLPMDEAGGQTRRSYLQLGDVATFEVAPGPNQISRENGKRRVVVTANV 839 Query: 839 RGRDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLF 898 RGRD+G FVAEAE+++Q AVKVPAGYWTTWGG FE LQSA +RLQIV+PVALL+VF+LLF Sbjct: 840 RGRDIGSFVAEAEQKIQQAVKVPAGYWTTWGGTFEQLQSAAKRLQIVVPVALLLVFMLLF 899 Query: 899 AMFSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFI 958 AMF+NVKDGLLVFTG+PFALTGGILAL +R IP+SISA VGFIALSGVAVLNGLVMI+FI Sbjct: 900 AMFNNVKDGLLVFTGVPFALTGGILALWLRDIPLSISAGVGFIALSGVAVLNGLVMIAFI 959 Query: 959 RSLREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGG 1018 R+LREEG++LD AIHEGA+TRLRPVLMTALVASLGF+PMA+ATGTGAEVQRPLATVVIGG Sbjct: 960 RTLREEGKSLDTAIHEGALTRLRPVLMTALVASLGFIPMAIATGTGAEVQRPLATVVIGG 1019 Query: 1019 ILSSTALTLLVLPLLYKLAHDKDEEDN 1045 ILSSTALTLLVLP+LY+LAH K+EE++ Sbjct: 1020 ILSSTALTLLVLPILYRLAHRKEEEED 1046 >ref|YP_001099897.1| RND divalent metal cation efflux transporter [Herminiimonas arsenicoxydans] emb|CAL61772.1| Cobalt-zinc-cadmium resistance protein CzcA (Cation efflux system protein CzcA) [Herminiimonas arsenicoxydans] Length = 1045 Score = 1676 bits (4341), Expect = 0.0, Method: Compositional matrix adjust. Identities = 818/1025 (79%), Positives = 928/1025 (90%), Gaps = 1/1025 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFER+IRFAIE RWLV+LAV GM G+Y+YQKLPIDAVPDITNVQVQINTSAPGYSPLE Sbjct: 1 MFERLIRFAIEQRWLVMLAVAGMAGLGIYNYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQRI++PIET+M+GLPNLEQ RSLSRYGLSQVTVIFKDGTDIYFARQ+VNERIQ+AR Sbjct: 61 TEQRITFPIETVMAGLPNLEQTRSLSRYGLSQVTVIFKDGTDIYFARQMVNERIQEARQN 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LPPGI P MGPISTGLGEIYLWTVE+++ A+K DG+ YT DLREIQDW+IK QLR V G Sbjct: 121 LPPGIAPAMGPISTGLGEIYLWTVEAKEGAKKADGSAYTPADLREIQDWIIKPQLRNVSG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEIN+IGGFAKEY VAP E+LASYG+++ ++ ALE+NN NVGAGYIE+RGEQ LIRA Sbjct: 181 VTEINSIGGFAKEYQVAPVPERLASYGLSLQDVVTALERNNGNVGAGYIEKRGEQLLIRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQV S+DDI NI+L NV+GV IRIRDV EVEIGRELRTGAATENGREVVLGTVFMLIG+ Sbjct: 241 PGQVQSMDDIRNIILGNVQGVAIRIRDVGEVEIGRELRTGAATENGREVVLGTVFMLIGQ 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQAV RKM EINR+LP GV+A+TVYDRTVLVDKAI+TVKKNL+EGA+LV+AVLF+ Sbjct: 301 NSRTVSQAVDRKMVEINRTLPAGVQAITVYDRTVLVDKAISTVKKNLLEGAVLVIAVLFI 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGN RAAIITAMVIPL+MLFTFTGMV+ VSANL+SLGALDFGII+DGAVVIVENCVRR Sbjct: 361 FLGNFRAAIITAMVIPLSMLFTFTGMVNYHVSANLMSLGALDFGIIVDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQAHHGR LTR+ERFHEVFAAAKEARRPLIFGQLIIM VYLP+FALTGVEG+MF PM Sbjct: 421 LAHAQAHHGRALTRTERFHEVFAAAKEARRPLIFGQLIIMAVYLPIFALTGVEGRMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAMILS+TFIPAAIALFIG KV EKEN LM A+ Y L ++M NKPVV Sbjct: 481 AFTVVIALVGAMILSITFIPAAIALFIGGKVEEKENRLMQQARTWYASALDSVMLNKPVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFA L+++ G++A+R+GSEFVP+LNEGD AIQALRIPGTSL+QS+ MQ+Q+EK LK+K Sbjct: 541 LTFAAVLVVLSGLLATRMGSEFVPNLNEGDFAIQALRIPGTSLTQSVAMQQQLEKLLKEK 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 PE+ER+FARTGTAE+ASDPMPPNISDGYIMLKPQ+QWPEP K+R++LL +Q VA +P Sbjct: 601 HPEIERIFARTGTAEIASDPMPPNISDGYIMLKPQDQWPEPVKTRDELLAVVQKTVASLP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 G++YEFSQPIQLRFNELISGVRSDVAVK+FGDDM VLNDTA K++AV+ KIPGA EVK+E Sbjct: 661 GSNYEFSQPIQLRFNELISGVRSDVAVKLFGDDMDVLNDTASKVAAVMGKIPGAAEVKVE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTV IDREKTARYGLN++D+QDTVATAIGGKEAGT+FQGDRRF I+VRLPD Sbjct: 721 QTTGLPMLTVNIDREKTARYGLNIADVQDTVATAIGGKEAGTLFQGDRRFNIIVRLPDHI 780 Query: 781 RTDLEAIRRLPIALPPQEGAT-RVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVR 839 R DLEAIRRLPI+LP +G+ R SY+PLGEV +L +APGPNQISREDGKRRIV+S NVR Sbjct: 781 RNDLEAIRRLPISLPRAQGSEGRTSYIPLGEVVTLDVAPGPNQISREDGKRRIVISTNVR 840 Query: 840 GRDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFA 899 GRD+G FVA+AE +++ V +P+GYWTTWGGQFE LQSATQRL+IVIPV LL+VFVLLFA Sbjct: 841 GRDIGSFVADAEAKIRQQVNIPSGYWTTWGGQFEQLQSATQRLKIVIPVTLLLVFVLLFA 900 Query: 900 MFSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIR 959 MF N+KDGLLVF+GIPFALTGGI+AL +R IPMSISAAVGFIALSGVAVLNGLVMISFIR Sbjct: 901 MFGNIKDGLLVFSGIPFALTGGIIALWLRDIPMSISAAVGFIALSGVAVLNGLVMISFIR 960 Query: 960 SLREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGI 1019 SLREEGR+L+ A+ +GA+TRLRPVLMTALVASLGF+PMA+ATGTGAEVQRPLATVVIGGI Sbjct: 961 SLREEGRSLEEAVRDGALTRLRPVLMTALVASLGFIPMAIATGTGAEVQRPLATVVIGGI 1020 Query: 1020 LSSTA 1024 LSSTA Sbjct: 1021 LSSTA 1025 >ref|YP_004682537.1| cation efflux system protein CzcA [Cupriavidus necator N-1] gb|AEI81305.1| cation efflux system protein CzcA [Cupriavidus necator N-1] Length = 1058 Score = 1673 bits (4333), Expect = 0.0, Method: Compositional matrix adjust. Identities = 806/1042 (77%), Positives = 925/1042 (88%), Gaps = 1/1042 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFER+IRFAIE RWLVLLAVLGM A G+YSY +LPIDAVPDITNVQVQINT+APGYSPLE Sbjct: 1 MFERLIRFAIEQRWLVLLAVLGMAALGLYSYTRLPIDAVPDITNVQVQINTAAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQRI+YP+ET+M+GLP LEQ RSLSRYGLSQVTVIF+DGTDI+FARQLVN+RIQ+AR + Sbjct: 61 TEQRITYPVETVMAGLPGLEQTRSLSRYGLSQVTVIFRDGTDIHFARQLVNQRIQEARDK 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP GI P MGPISTGLGEIYLWTVE+ ARKPDGTPYT +DLREIQDWVI+ QLR VPG Sbjct: 121 LPAGITPAMGPISTGLGEIYLWTVEADPGARKPDGTPYTLSDLREIQDWVIRPQLRNVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTE+N IGG A+ Y+VAPS E++ASYG+++ ++ ALEKNN NVGAGYIERRGEQYL+R Sbjct: 181 VTEVNAIGGHARAYVVAPSLERMASYGLSLADVVSALEKNNDNVGAGYIERRGEQYLVRV 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQV S+DDI ++++ +G PIR+RDVA V+ G ELRTGAATENGREVVLGTVFMLIGE Sbjct: 241 PGQVRSLDDIRDVIVGTAQGQPIRVRDVATVQTGGELRTGAATENGREVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQA RKM EINR+LPKGV+AVTVYDRT LVDKAIATVKKNL+EGA+LV+A+LF+ Sbjct: 301 NSRTVSQAADRKMAEINRTLPKGVQAVTVYDRTTLVDKAIATVKKNLLEGAVLVIAILFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGN+RAA+ITA+VIPL+MLFTFTGMV ++SANL+SLGALDFGII+DGAVVIVENCVRR Sbjct: 361 FLGNLRAALITALVIPLSMLFTFTGMVQYRISANLMSLGALDFGIIVDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQ HGR LTR ER HEVFAAA+EARRPL++GQLIIM+VYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQERHGRPLTRGERLHEVFAAAREARRPLLYGQLIIMVVYLPIFALTGVEGKMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAM+LSVTF+PAA+ALFIG +VAE+EN LM WA+R Y +L+ + PVV Sbjct: 481 AFTVVLALLGAMVLSVTFVPAAVALFIGNRVAERENRLMAWARRRYAVLLERSLAATPVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFAG + +C + +RLGSEFVPSLNEGD+AIQALRIPGTSL+QS+ MQ+Q+E LK K Sbjct: 541 LTFAGVAVALCLAIGTRLGSEFVPSLNEGDLAIQALRIPGTSLTQSVAMQQQVETALKAK 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPE+ER+FARTGTAE+ASDPMPPNISDGYIMLKP QWPEP+++R++L+ AI+DEV K+P Sbjct: 601 FPEIERIFARTGTAEIASDPMPPNISDGYIMLKPVSQWPEPRRTRDELIAAIRDEVGKLP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSDVAVKVFGDD VL TA +I+AVL+ IPGA EVK+E Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDVAVKVFGDDNAVLEQTANRIAAVLQGIPGAAEVKVE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTV+IDR K ARYGLN+SDIQD VA IGGK +GT F GDRRF IVVRLPD Sbjct: 721 QTTGLPMLTVQIDRNKAARYGLNLSDIQDAVAIGIGGKVSGTFFSGDRRFDIVVRLPDAV 780 Query: 781 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG 840 R D+EA+RRLP+ L P+E A R SY+PL EVAS+ IAPGPNQ+SRE+GKRRIVVSANVRG Sbjct: 781 REDVEALRRLPVPL-PKEAAARTSYIPLSEVASVEIAPGPNQVSRENGKRRIVVSANVRG 839 Query: 841 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM 900 RD+G FV EAE +++ V++PAGYWT+WGG FE LQSAT RL+IV+P+AL MVFVLLFAM Sbjct: 840 RDIGSFVPEAEAAIRARVQIPAGYWTSWGGTFEQLQSATARLRIVVPLALGMVFVLLFAM 899 Query: 901 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS 960 F NVKDGLLVFTGIPFALTGGILAL +RGIP+SISAAVGFIAL GVAVLNGLVM+SFIRS Sbjct: 900 FGNVKDGLLVFTGIPFALTGGILALWLRGIPLSISAAVGFIALCGVAVLNGLVMLSFIRS 959 Query: 961 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1020 LRE+G LDAAI +GA+TRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL Sbjct: 960 LREDGHGLDAAIRDGALTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1019 Query: 1021 SSTALTLLVLPLLYKLAHDKDE 1042 SSTALTLLVLP+LY+LAH DE Sbjct: 1020 SSTALTLLVLPVLYRLAHRNDE 1041 >ref|YP_841919.1| cation/multidrug efflux pump [Ralstonia eutropha H16] emb|CAJ97189.1| Cation/multidrug efflux pump [Ralstonia eutropha H16] Length = 1058 Score = 1665 bits (4313), Expect = 0.0, Method: Compositional matrix adjust. Identities = 802/1042 (76%), Positives = 924/1042 (88%), Gaps = 1/1042 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFER+IRFAIE RWLVLLAVLGM A G+YSY +LPIDAVPDITNVQVQINT+APGYSPLE Sbjct: 1 MFERLIRFAIEQRWLVLLAVLGMAALGLYSYTRLPIDAVPDITNVQVQINTAAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQRI+YP+ET M+GLP LEQ RSLSRYGLSQVTVIF+DGT I+FARQLVN+RIQ+AR + Sbjct: 61 TEQRITYPVETAMAGLPGLEQTRSLSRYGLSQVTVIFRDGTGIHFARQLVNQRIQEARDK 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP GI P MGPISTGLGEIYLWTVE+ ARKPDGTPYT +DLREIQDWVI+ QLR VPG Sbjct: 121 LPAGITPAMGPISTGLGEIYLWTVEADPGARKPDGTPYTLSDLREIQDWVIRPQLRNVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTE+N IGG A+ Y+VAPS E++ASYG+++ ++ ALEKNN NVGAGYIERRGEQYL+R Sbjct: 181 VTEVNAIGGHARAYVVAPSLERMASYGLSLADVVSALEKNNDNVGAGYIERRGEQYLVRV 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQV S++DI ++++ +G+PIR+RDVA V+ G ELRTGAATENGREVVLGTVFMLIGE Sbjct: 241 PGQVRSLEDIRDVIVGTAQGLPIRVRDVATVQTGGELRTGAATENGREVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VSQAV RKM EINR+L KGV+AVTVYDRT LVDKAIATVKKNL+EGA+LV+A+LF+ Sbjct: 301 NSRTVSQAVDRKMAEINRTLSKGVQAVTVYDRTTLVDKAIATVKKNLLEGAVLVIAILFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGN+RAA+ITA+VIPL+MLFTFTGMV ++SANL+SLGALDFGII+DGAVVIVENCVRR Sbjct: 361 FLGNLRAALITALVIPLSMLFTFTGMVHYRISANLMSLGALDFGIIVDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQ HG LTRSER HEVFAAA+EARRPL++GQLIIM+VYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQERHGHPLTRSERLHEVFAAAREARRPLLYGQLIIMVVYLPIFALTGVEGKMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAM+LSVTF+PAA+A FIG +VAE+EN LM WA+R Y +L+ + PVV Sbjct: 481 AFTVVLALLGAMVLSVTFVPAAVAQFIGNRVAERENRLMAWARRRYAVLLERSLAATPVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFAG + +C +A+RLGSEFVPSLNEGD+AIQALRIPGTSL+QS+ MQ+Q+E LK + Sbjct: 541 LTFAGVAVALCLAIATRLGSEFVPSLNEGDLAIQALRIPGTSLTQSVAMQQQVETALKAR 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPE+ER+FARTGTAE+ASDPMPPNISDGYIMLKP QWPEP+++R+QL+ AI+DEV K+P Sbjct: 601 FPEIERIFARTGTAEIASDPMPPNISDGYIMLKPMSQWPEPRRTRDQLIAAIRDEVGKLP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSDVAVKVFGDD VL TA +I+AVL+ IPGA EV++E Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDVAVKVFGDDNAVLEQTANRIAAVLQGIPGAAEVRVE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTV+IDR K ARYGLN+SDIQD VA IGGK +GT F GDRRF IVVRLPD Sbjct: 721 QTTGLPMLTVQIDRNKAARYGLNLSDIQDAVAIGIGGKVSGTFFSGDRRFDIVVRLPDAV 780 Query: 781 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG 840 R D+EA+RRLP+ L P+E A R SY+PL EVAS+ IAPGPNQ+SRE+GKRRIVVSANVRG Sbjct: 781 REDVEALRRLPVPL-PKEAAARTSYIPLSEVASVDIAPGPNQVSRENGKRRIVVSANVRG 839 Query: 841 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM 900 RD+G FV EAE +++ V++PAGYWT+WGG FE LQSAT RL++V+P+AL +VFVLLFAM Sbjct: 840 RDIGSFVPEAEAAIRARVQIPAGYWTSWGGTFEQLQSATARLRVVVPLALGLVFVLLFAM 899 Query: 901 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS 960 F NVKDGLLVFTGIPFALTGGILAL +RGIP+SISAAVGFIAL GVAVLNGLVM+SFIRS Sbjct: 900 FGNVKDGLLVFTGIPFALTGGILALWLRGIPLSISAAVGFIALCGVAVLNGLVMLSFIRS 959 Query: 961 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1020 LREEG LDAAI +GA+TRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL Sbjct: 960 LREEGHGLDAAIRDGALTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1019 Query: 1021 SSTALTLLVLPLLYKLAHDKDE 1042 SSTALTLLVLP+LY+LAH DE Sbjct: 1020 SSTALTLLVLPVLYRLAHRNDE 1041 >ref|YP_001899332.1| CzcA family heavy metal efflux pump [Ralstonia pickettii 12J] sp|P94177.1|CZCA_ALCSC RecName: Full=Cation efflux system protein CzcA dbj|BAA11061.1| CzcA [Alcaligenes sp.] gb|ACD26900.1| heavy metal efflux pump, CzcA family [Ralstonia pickettii 12J] Length = 1063 Score = 1664 bits (4309), Expect = 0.0, Method: Compositional matrix adjust. Identities = 819/1043 (78%), Positives = 934/1043 (89%), Gaps = 1/1043 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFERII FAI+ RWLVLLAV GM G++SY +LPIDAVPDITNVQVQ+NTSAPGYSPLE Sbjct: 1 MFERIISFAIQQRWLVLLAVFGMAGLGIFSYNRLPIDAVPDITNVQVQVNTSAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQR++YPIE +M+GLP LEQ RSLSRYGLSQVTVIFKDGTD+YFARQLVN+RIQ+A+ Sbjct: 61 TEQRVTYPIEVVMAGLPGLEQTRSLSRYGLSQVTVIFKDGTDVYFARQLVNQRIQEAKDN 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP G+ P MGPISTGLGEIYLWTVE+ + ARK DGT YT TDLREIQDWV++ QLR VPG Sbjct: 121 LPEGVVPAMGPISTGLGEIYLWTVEAEEGARKADGTAYTPTDLREIQDWVVRPQLRNVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEINTIGGF K+YLVAPS E+LASYG+T+ ++ AL KNN NVGAGYIERRGEQYL+RA Sbjct: 181 VTEINTIGGFNKQYLVAPSLERLASYGLTLTDVVNALNKNNDNVGAGYIERRGEQYLVRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQVAS DDI NI++ +G PIRIRD+ +VEIG+ELRTGAATENG+EVVLGTVFMLIGE Sbjct: 241 PGQVASEDDIRNIIVGTAQGQPIRIRDIGDVEIGKELRTGAATENGKEVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VS+AV K+ INR++P+GV+ VTVYDRT LVDKAIATVKKNL+EGA+LV+ +LF+ Sbjct: 301 NSRAVSKAVDEKVASINRTMPEGVKIVTVYDRTRLVDKAIATVKKNLLEGAVLVIVILFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGNIRAA+ITA +IPLAMLFTFTGMV+ K+SANL+SLGALDFGIIIDGAVVIVENCVRR Sbjct: 361 FLGNIRAALITATIIPLAMLFTFTGMVNYKISANLMSLGALDFGIIIDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQ HHGR LTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQEHHGRPLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPIFALTGVEGKMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAMILSVTF+PAA+ALFIGE+VAEKEN LMLWAKR YEP+L+ + N VV Sbjct: 481 AFTVVLALLGAMILSVTFVPAAVALFIGERVAEKENRLMLWAKRRYEPLLEKSLANTAVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFA I++C +A+RLGSEF+P+LNEGD+AIQALRIPGTSLSQS+EMQK IE TLK K Sbjct: 541 LTFAAVSIVLCVAIAARLGSEFIPNLNEGDIAIQALRIPGTSLSQSVEMQKTIETTLKAK 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPE+ERVFARTGTAE+ASDPMPPNISDGYIMLKP++ WPEPKK+ +LL AIQ+E KIP Sbjct: 601 FPEIERVFARTGTAEIASDPMPPNISDGYIMLKPEKDWPEPKKTHAELLSAIQEEAGKIP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSDVAVK+FGDD VL++TA K+SAVL+ IPGA EVK+E Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDVAVKIFGDDNNVLSETAKKVSAVLQGIPGAQEVKVE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTV+IDREK ARYGLN+SD+QD VAT +GG+++GT FQGDRRF IVVRLP+ Sbjct: 721 QTTGLPMLTVKIDREKAARYGLNMSDVQDAVATGVGGRDSGTFFQGDRRFDIVVRLPEAV 780 Query: 781 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG 840 R ++EA+RRLPI LP A R +++PL EVA+L +APGPNQISRE+GKRRIV+SANVRG Sbjct: 781 RGEVEALRRLPIPLPKGVDA-RTTFIPLSEVATLEMAPGPNQISRENGKRRIVISANVRG 839 Query: 841 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM 900 RD+G FV EAE +QS VK+PAGYW TWGG FE LQSAT RLQ+V+PVALL+VFVLLFAM Sbjct: 840 RDIGSFVPEAEAAIQSQVKIPAGYWMTWGGTFEQLQSATTRLQVVVPVALLLVFVLLFAM 899 Query: 901 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS 960 F+N+KDGLLVFTGIPFALTGGILAL +RGIPMSI+AAVGFIAL GVAVLNGLVM+SFIRS Sbjct: 900 FNNIKDGLLVFTGIPFALTGGILALWIRGIPMSITAAVGFIALCGVAVLNGLVMLSFIRS 959 Query: 961 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1020 LREEG +LD+A+ GA+TRLRPVLMTALVASLGFVPMA+ATGTGAEVQRPLATVVIGGIL Sbjct: 960 LREEGHSLDSAVRVGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIL 1019 Query: 1021 SSTALTLLVLPLLYKLAHDKDEE 1043 SSTALTLLVLP+LY+LAH KDE+ Sbjct: 1020 SSTALTLLVLPVLYRLAHRKDED 1042 >ref|YP_145595.1| cation efflux system transmembrane protein [Ralstonia metallidurans CH34] ref|YP_581789.1| heavy metal resistance protein CzcA [Cupriavidus metallidurans CH34] sp|P13511.3|CZCA_RALME RecName: Full=Cobalt-zinc-cadmium resistance protein CzcA; AltName: Full=Cation efflux system protein CzcA emb|CAI11244.1| cation efflux system transmembrane protein [Cupriavidus metallidurans CH34] gb|ABF12839.1| CzcA, efflux chemoosmotic pump, three components cation proton antiporter efflux system involved in Cd(II), Zn(II), Co(II) resistance [Cupriavidus metallidurans CH34] Length = 1063 Score = 1659 bits (4296), Expect = 0.0, Method: Compositional matrix adjust. Identities = 818/1043 (78%), Positives = 932/1043 (89%), Gaps = 1/1043 (0%) Query: 1 MFERIIRFAIEHRWLVLLAVLGMGAYGVYSYQKLPIDAVPDITNVQVQINTSAPGYSPLE 60 MFERII FAI+ RWLVLLAV GM G++SY +LPIDAVPDITNVQVQ+NTSAPGYSPLE Sbjct: 1 MFERIISFAIQQRWLVLLAVFGMAGLGIFSYNRLPIDAVPDITNVQVQVNTSAPGYSPLE 60 Query: 61 AEQRISYPIETLMSGLPNLEQVRSLSRYGLSQVTVIFKDGTDIYFARQLVNERIQQARSQ 120 EQR +YPIE +M+GLP LEQ RSLSRYGLSQVTVIFKDGTD+YFARQLVN+RIQ+A+ Sbjct: 61 TEQRATYPIEVVMAGLPGLEQTRSLSRYGLSQVTVIFKDGTDVYFARQLVNQRIQEAKDN 120 Query: 121 LPPGIDPGMGPISTGLGEIYLWTVESRDDARKPDGTPYTATDLREIQDWVIKLQLRLVPG 180 LP G+ P MGPISTGLGEIYLWTVE+ + ARK DGT YT TDLREIQDWV++ QLR VPG Sbjct: 121 LPEGVVPAMGPISTGLGEIYLWTVEAEEGARKADGTAYTPTDLREIQDWVVRPQLRNVPG 180 Query: 181 VTEINTIGGFAKEYLVAPSAEKLASYGMTMDTIIKALEKNNSNVGAGYIERRGEQYLIRA 240 VTEINTIGGF K+YLVAPS E+LASYG+T+ ++ AL KNN NVGAGYIERRGEQYL+RA Sbjct: 181 VTEINTIGGFNKQYLVAPSLERLASYGLTLTDVVNALNKNNDNVGAGYIERRGEQYLVRA 240 Query: 241 PGQVASIDDIGNIVLANVKGVPIRIRDVAEVEIGRELRTGAATENGREVVLGTVFMLIGE 300 PGQVAS DDI NI++ +G PIRIRD+ +VEIG+ELRTGAATENG+EVVLGTVFMLIGE Sbjct: 241 PGQVASEDDIRNIIVGTAQGQPIRIRDIGDVEIGKELRTGAATENGKEVVLGTVFMLIGE 300 Query: 301 NSRKVSQAVARKMEEINRSLPKGVEAVTVYDRTVLVDKAIATVKKNLVEGALLVVAVLFV 360 NSR VS+AV K+ INR++P+GV+ VTVYDRT LVDKAIATVKKNL+EGA+LV+ +LF+ Sbjct: 301 NSRAVSKAVDEKVASINRTMPEGVKIVTVYDRTRLVDKAIATVKKNLLEGAVLVIVILFL 360 Query: 361 FLGNIRAAIITAMVIPLAMLFTFTGMVSNKVSANLLSLGALDFGIIIDGAVVIVENCVRR 420 FLGNIRAA+ITA +IPLAMLFTFTGMV+ K+SANL+SLGALDFGIIIDGAVVIVENCVRR Sbjct: 361 FLGNIRAALITATIIPLAMLFTFTGMVNYKISANLMSLGALDFGIIIDGAVVIVENCVRR 420 Query: 421 LAHAQAHHGRTLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPMFALTGVEGKMFTPM 480 LAHAQ HHGR LTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLP+FALTGVEGKMF PM Sbjct: 421 LAHAQEHHGRPLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPIFALTGVEGKMFHPM 480 Query: 481 AFTVVAALIGAMILSVTFIPAAIALFIGEKVAEKENILMLWAKRLYEPMLKTIMENKPVV 540 AFTVV AL+GAMILSVTF+PAA+ALFIGE+VAEKEN LMLWAKR YEP+L+ + N VV Sbjct: 481 AFTVVLALLGAMILSVTFVPAAVALFIGERVAEKENRLMLWAKRRYEPLLEKSLANTAVV 540 Query: 541 LTFAGALILVCGVVASRLGSEFVPSLNEGDMAIQALRIPGTSLSQSLEMQKQIEKTLKQK 600 LTFA I++C +A+RLGSEF+P+LNEGD+AIQALRIPGTSLSQS+EMQK IE TLK K Sbjct: 541 LTFAAVSIVLCVAIAARLGSEFIPNLNEGDIAIQALRIPGTSLSQSVEMQKTIETTLKAK 600 Query: 601 FPEVERVFARTGTAEVASDPMPPNISDGYIMLKPQEQWPEPKKSREQLLEAIQDEVAKIP 660 FPE+ERVFARTGTAE+ASD MPPNISDGYIMLKP++ WPEPKK+ +LL AIQ+E KIP Sbjct: 601 FPEIERVFARTGTAEIASDLMPPNISDGYIMLKPEKDWPEPKKTHAELLSAIQEEAGKIP 660 Query: 661 GNSYEFSQPIQLRFNELISGVRSDVAVKVFGDDMKVLNDTAGKISAVLEKIPGATEVKIE 720 GN+YEFSQPIQLRFNELISGVRSDVAVK+FGDD VL++TA K+SAVL+ IPGA EVK+E Sbjct: 661 GNNYEFSQPIQLRFNELISGVRSDVAVKIFGDDNNVLSETAKKVSAVLQGIPGAQEVKVE 720 Query: 721 QTTGLPMLTVEIDREKTARYGLNVSDIQDTVATAIGGKEAGTMFQGDRRFGIVVRLPDQA 780 QTTGLPMLTV+IDREK ARYGLN+SD+QD VAT +GG+++GT FQGDRRF IVVRLP+ Sbjct: 721 QTTGLPMLTVKIDREKAARYGLNMSDVQDAVATGVGGRDSGTFFQGDRRFDIVVRLPEAV 780 Query: 781 RTDLEAIRRLPIALPPQEGATRVSYVPLGEVASLTIAPGPNQISREDGKRRIVVSANVRG 840 R ++EA+RRLPI LP A R +++PL EVA+L +APGPNQISRE+GKRRIV+SANVRG Sbjct: 781 RGEVEALRRLPIPLPKGVDA-RTTFIPLSEVATLEMAPGPNQISRENGKRRIVISANVRG 839 Query: 841 RDLGGFVAEAERQLQSAVKVPAGYWTTWGGQFENLQSATQRLQIVIPVALLMVFVLLFAM 900 RD+G FV EAE +QS VK+PAGYW TWGG FE LQSAT RLQ+V+PVALL+VFVLLFAM Sbjct: 840 RDIGSFVPEAEAAIQSQVKIPAGYWMTWGGTFEQLQSATTRLQVVVPVALLLVFVLLFAM 899 Query: 901 FSNVKDGLLVFTGIPFALTGGILALAMRGIPMSISAAVGFIALSGVAVLNGLVMISFIRS 960 F+N+KDGLLVFTGIPFALTGGILAL +RGIPMSI+AAVGFIAL GVAVLNGLVM+SFIRS Sbjct: 900 FNNIKDGLLVFTGIPFALTGGILALWIRGIPMSITAAVGFIALCGVAVLNGLVMLSFIRS 959 Query: 961 LREEGRTLDAAIHEGAMTRLRPVLMTALVASLGFVPMALATGTGAEVQRPLATVVIGGIL 1020 LREEG +LD+A+ GA+TRLRPVLMTALVASLGFVPMA+ATGTGAEVQRPLATVVIGGIL Sbjct: 960 LREEGHSLDSAVRVGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIL 1019 Query: 1021 SSTALTLLVLPLLYKLAHDKDEE 1043 SSTALTLLVLP+LY+LAH KDE+ Sbjct: 1020 SSTALTLLVLPVLYRLAHRKDED 1042