BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0076.p (255 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777774.1| short-chain alcohol dehydrogenase [Herbaspir... 508 e-142 ref|YP_001101419.1| short chain dehydrogenase [Herminiimonas ars... 362 3e-98 ref|YP_001355126.1| short chain dehydrogenase [Janthinobacterium... 355 3e-96 ref|ZP_08273770.1| FolM Alternative dihydrofolate reductase 1 [O... 345 3e-93 ref|YP_004229808.1| short-chain dehydrogenase/reductase SDR [Bur... 325 5e-87 ref|YP_002980030.1| short chain dehydrogenase [Ralstonia pickett... 314 1e-83 emb|CCA88443.1| short chain dehydrogenase [Ralstonia syzygii R24] 313 1e-83 emb|CCA80372.1| short chain dehydrogenase [blood disease bacteri... 313 2e-83 gb|AEG70500.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Ralst... 313 2e-83 ref|YP_001897646.1| short chain dehydrogenase [Ralstonia pickett... 313 2e-83 >ref|YP_003777774.1| short-chain alcohol dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ65866.1| short-chain alcohol dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 255 Score = 508 bits (1309), Expect = e-142, Method: Compositional matrix adjust. Identities = 252/255 (98%), Positives = 253/255 (99%) Query: 1 MTSPSSAGIALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRAL 60 MTSPSSAGIALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREI+ LGRRAL Sbjct: 1 MTSPSSAGIALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIETLGRRAL 60 Query: 61 AVQAELGDETQVRSLLPQAAPLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPV 120 AVQAELGDETQVRSLLPQAAPLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPV Sbjct: 61 AVQAELGDETQVRSLLPQAAPLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPV 120 Query: 121 LLAQALYEATPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRV 180 LLAQALYEATP GQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRV Sbjct: 121 LLAQALYEATPQGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRV 180 Query: 181 VGVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGG 240 VGVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGG Sbjct: 181 VGVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGG 240 Query: 241 QHLLPLSRDVMFVAK 255 QHLLPLSRDVMFVAK Sbjct: 241 QHLLPLSRDVMFVAK 255 >ref|YP_001101419.1| short chain dehydrogenase [Herminiimonas arsenicoxydans] emb|CAL63298.1| Putative short chain dehydrogenase [Herminiimonas arsenicoxydans] Length = 259 Score = 362 bits (929), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 183/251 (72%), Positives = 208/251 (82%), Gaps = 1/251 (0%) Query: 5 SSAGIALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQA 64 +S ALVTG ARRIGR IALALAQ GWDV VHY RS ++A V +IQ LG+RA+A+ Sbjct: 8 ASKKTALVTGGARRIGRTIALALAQRGWDVVVHYARSADDARATVADIQTLGQRAIALSC 67 Query: 65 ELGDETQVRSLLPQA-APLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLA 123 +L DET V+SLL +A A LG ISCVVNNASLFDYD AA F L HM N+ APVLLA Sbjct: 68 DLNDETAVKSLLRRASAQLGPISCVVNNASLFDYDSAADFSTASLDAHMHVNLVAPVLLA 127 Query: 124 QALYEATPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGV 183 QALYEATP QAVV+NLLDQKL+N NPDFLSYTLSKAALHSATT+LAQALAPKVRVVGV Sbjct: 128 QALYEATPAHGQAVVVNLLDQKLFNLNPDFLSYTLSKAALHSATTMLAQALAPKVRVVGV 187 Query: 184 APGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHL 243 APG+T+VSGDQ+E +F +AH+VTPLGR STP+DIAAAVC+VA A A+TGTTL+VDGGQHL Sbjct: 188 APGITLVSGDQSEAEFARAHKVTPLGRSSTPDDIAAAVCFVAEAPAITGTTLVVDGGQHL 247 Query: 244 LPLSRDVMFVA 254 +PL RDVMFVA Sbjct: 248 VPLQRDVMFVA 258 >ref|YP_001355126.1| short chain dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR90775.1| Uncharacterized conserved protein [Janthinobacterium sp. Marseille] Length = 259 Score = 355 bits (912), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 178/246 (72%), Positives = 206/246 (83%), Gaps = 1/246 (0%) Query: 10 ALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGDE 69 ALVTGAARRIGR IALALAQ GWDV VHY+RS EA V +I ALG+RA+A+Q +L DE Sbjct: 13 ALVTGAARRIGRTIALALAQGGWDVVVHYSRSESEAQATVADIIALGQRAIALQCDLADE 72 Query: 70 TQVRSLLPQAAP-LGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQALYE 128 V++LL +AA LG ISCVVNNASLFDYD AA F L HM N+ AP+LLAQAL++ Sbjct: 73 AAVKTLLRRAATQLGPISCVVNNASLFDYDSAADFSVATLDAHMHTNLAAPILLAQALHQ 132 Query: 129 ATPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVAPGLT 188 ATP G QAVV+NLLDQKL+N NPDFLSYTLSKAALH+ATT+LAQALAPKVRVVGVAPG+T Sbjct: 133 ATPEGAQAVVVNLLDQKLFNLNPDFLSYTLSKAALHTATTMLAQALAPKVRVVGVAPGIT 192 Query: 189 MVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHLLPLSR 248 +VSGDQ+E +F +AH+VTPLGR STP+DIA AV +V A+A+TGTTLLVDGGQHL+PL R Sbjct: 193 LVSGDQSEAEFERAHKVTPLGRSSTPDDIAHAVRFVVEAQAMTGTTLLVDGGQHLIPLQR 252 Query: 249 DVMFVA 254 DVMFVA Sbjct: 253 DVMFVA 258 >ref|ZP_08273770.1| FolM Alternative dihydrofolate reductase 1 [Oxalobacteraceae bacterium IMCC9480] gb|EGF32766.1| FolM Alternative dihydrofolate reductase 1 [Oxalobacteraceae bacterium IMCC9480] Length = 258 Score = 345 bits (886), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 172/250 (68%), Positives = 201/250 (80%), Gaps = 4/250 (1%) Query: 9 IALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGD 68 +ALVTGAA+RIGR IALALA+ GWDV VHY RS EA T V EI+ LGRRA A+Q +L D Sbjct: 8 VALVTGAAKRIGRTIALALAERGWDVIVHYGRSAGEAATTVHEIEQLGRRAWALQCDLTD 67 Query: 69 ETQVRSLLPQA----APLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQ 124 E V+ LLP A P R++CVVNNASLF+ D A F L HM AN+ AP+LLAQ Sbjct: 68 EQAVKKLLPDAIACCGPQSRLACVVNNASLFEQDGPADFSLAVLDEHMHANLAAPILLAQ 127 Query: 125 ALYEATPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVA 184 AL+ ATP G+Q+VVINLLDQKL+N NPDFLSYTLSKAAL +AT +LAQALAPK+RVVGVA Sbjct: 128 ALHAATPDGEQSVVINLLDQKLFNMNPDFLSYTLSKAALQTATVMLAQALAPKLRVVGVA 187 Query: 185 PGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHLL 244 PG+T++SGDQ++ F KAH++TPLGR STPEDIA AVCYVA A A+TGTTLLVDGGQHL+ Sbjct: 188 PGITLISGDQSQASFEKAHKITPLGRSSTPEDIADAVCYVAGAHAMTGTTLLVDGGQHLI 247 Query: 245 PLSRDVMFVA 254 PL RD+MFVA Sbjct: 248 PLQRDIMFVA 257 >ref|YP_004229808.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. CCGE1001] gb|ADX56748.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. CCGE1001] Length = 272 Score = 325 bits (832), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 167/252 (66%), Positives = 196/252 (77%), Gaps = 7/252 (2%) Query: 9 IALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGD 68 + L+TGAARRIGR +AL A GWDVAVHY SR EA+ +V EI ALGRRA+A+ AELGD Sbjct: 18 VVLITGAARRIGRALALGFAAQGWDVAVHYGASRREAEEVVGEITALGRRAVALHAELGD 77 Query: 69 ETQVRSLLPQA-APLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQALY 127 ETQV LLP A LGR +C+VNNAS F+ D A + G E LL+ + N+GAP++LA+ LY Sbjct: 78 ETQVAGLLPACTAALGRPACIVNNASRFEEDTARNVGYELLLKLTAMNLGAPLVLARMLY 137 Query: 128 EATPPG------QQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVV 181 +ATPP Q++VVIN+LDQKLYN NPD+LSYTLSKAAL +AT LAQALAPKVRVV Sbjct: 138 DATPPAALTDETQRSVVINVLDQKLYNMNPDYLSYTLSKAALQTATVALAQALAPKVRVV 197 Query: 182 GVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQ 241 G+APGLTM SGDQT E F AH+VTPLGR S PEDI AA Y+A A VTGTTL+VDGGQ Sbjct: 198 GLAPGLTMQSGDQTAESFAAAHRVTPLGRASRPEDIVAAALYLADATGVTGTTLVVDGGQ 257 Query: 242 HLLPLSRDVMFV 253 HL+PL RDVMF+ Sbjct: 258 HLVPLPRDVMFL 269 >ref|YP_002980030.1| short chain dehydrogenase [Ralstonia pickettii 12D] gb|ACS61358.1| short-chain dehydrogenase/reductase SDR [Ralstonia pickettii 12D] Length = 272 Score = 314 bits (804), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 164/251 (65%), Positives = 195/251 (77%), Gaps = 4/251 (1%) Query: 9 IALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGD 68 IALVTGA RR+GR IALALA+ GWDVAVH +RSR EAD + EI A+GRRA+ +QA+L D Sbjct: 22 IALVTGAGRRVGRVIALALARHGWDVAVHCHRSRTEADAVAAEITAMGRRAVVLQADLSD 81 Query: 69 ETQVRSLLPQ-AAPLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQALY 127 E L+ +A LG +C+VNNASLF YD A SF L HM NV AP+LL++ L+ Sbjct: 82 EAAAGRLIADCSAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLSRELH 141 Query: 128 EA-TPPG--QQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVA 184 A T G + VVINLLDQKL N NPDFLSYTLSKAAL +AT LAQALAP +RVVGVA Sbjct: 142 RALTADGAEHRGVVINLLDQKLDNLNPDFLSYTLSKAALSTATMQLAQALAPALRVVGVA 201 Query: 185 PGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHLL 244 PG+TMVSGDQ++ F +AHQ+TPLG+ STPEDIA AVCY+A+ARAVTGTTL VDGGQHL+ Sbjct: 202 PGITMVSGDQSQGGFARAHQMTPLGQSSTPEDIAEAVCYLATARAVTGTTLFVDGGQHLM 261 Query: 245 PLSRDVMFVAK 255 PL+RDVMF+ + Sbjct: 262 PLARDVMFLTE 272 >emb|CCA88443.1| short chain dehydrogenase [Ralstonia syzygii R24] Length = 267 Score = 313 bits (803), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 163/254 (64%), Positives = 195/254 (76%), Gaps = 7/254 (2%) Query: 9 IALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGD 68 IALVTGAARR+GR IALALA+ GWD+AVH +RSR EADT+ EI A+GRRA +QA+L D Sbjct: 14 IALVTGAARRVGRVIALALARQGWDIAVHCHRSRAEADTVAAEIAAMGRRAAVLQADLSD 73 Query: 69 ETQVRSLLPQA-APLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQALY 127 E L+ A LG +C+VNNASLF YD A SF L HM NV AP+LL++ L+ Sbjct: 74 EAAAGRLIADCIAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLSRELH 133 Query: 128 EA------TPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVV 181 A + + VVINLLDQKL N NPDFLSYTLSKAAL +ATT LAQALAP +RVV Sbjct: 134 RALTAEDGSARDVRGVVINLLDQKLNNLNPDFLSYTLSKAALATATTQLAQALAPALRVV 193 Query: 182 GVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQ 241 GVAPG+T+VSGDQ+ +F +AHQ+TPLG+ STPEDIA AVCY+A+ARAVTGTTL VDGGQ Sbjct: 194 GVAPGITLVSGDQSASEFARAHQMTPLGQSSTPEDIAEAVCYLATARAVTGTTLFVDGGQ 253 Query: 242 HLLPLSRDVMFVAK 255 HL+PL+RDVMF+ + Sbjct: 254 HLMPLARDVMFLTE 267 >emb|CCA80372.1| short chain dehydrogenase [blood disease bacterium R229] Length = 267 Score = 313 bits (802), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 163/254 (64%), Positives = 195/254 (76%), Gaps = 7/254 (2%) Query: 9 IALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGD 68 IALVTGAARR+GR IALALA+ GWD+AVH +RSR EADT+ EI A+GRRA +QA+L D Sbjct: 14 IALVTGAARRVGRVIALALARQGWDIAVHCHRSRAEADTVAAEIAAMGRRAAVLQADLSD 73 Query: 69 ETQVRSLLPQA-APLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQALY 127 E L+ A LG +C+VNNASLF YD A SF L HM NV AP+LL++ L+ Sbjct: 74 EAAAGRLIADCIAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLSRELH 133 Query: 128 EA------TPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVV 181 A + + VVINLLDQKL N NPDFLSYTLSKAAL +ATT LAQALAP +RVV Sbjct: 134 RALTAEDGSARDVRGVVINLLDQKLNNLNPDFLSYTLSKAALATATTQLAQALAPVLRVV 193 Query: 182 GVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQ 241 GVAPG+T+VSGDQ+ +F +AHQ+TPLG+ STPEDIA AVCY+A+ARAVTGTTL VDGGQ Sbjct: 194 GVAPGITLVSGDQSASEFARAHQMTPLGQSSTPEDIAEAVCYLATARAVTGTTLFVDGGQ 253 Query: 242 HLLPLSRDVMFVAK 255 HL+PL+RDVMF+ + Sbjct: 254 HLMPLARDVMFLTE 267 >gb|AEG70500.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Ralstonia solanacearum Po82] Length = 271 Score = 313 bits (802), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 164/261 (62%), Positives = 197/261 (75%), Gaps = 7/261 (2%) Query: 2 TSPSSAGIALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALA 61 +SP IALVTGAARR+GR IALALA+ GWDVAVH +RSR EADT+ EI A+GRRA Sbjct: 11 SSPVPPRIALVTGAARRVGRVIALALARQGWDVAVHCHRSRAEADTVAAEITAMGRRATV 70 Query: 62 VQAELGDETQVRSLLPQA-APLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPV 120 +QA+L DE L+ A LG +C+VNNASLF YD A SF L HM NV AP+ Sbjct: 71 LQADLSDEAATGRLIADCIAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPL 130 Query: 121 LLAQALYEA------TPPGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQAL 174 LL++ L+ A + G + VVINLLDQKL N NPDFLSYTLSKAAL +AT LAQAL Sbjct: 131 LLSRELHRALTAEDGSARGVRGVVINLLDQKLDNLNPDFLSYTLSKAALATATMQLAQAL 190 Query: 175 APKVRVVGVAPGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTT 234 AP +RVVGVAPG+T+VSGDQ+ F +AHQ+TPLG+ STPEDIA AVC++A++RAVTGTT Sbjct: 191 APVLRVVGVAPGITLVSGDQSSSGFARAHQMTPLGQSSTPEDIAEAVCFLATSRAVTGTT 250 Query: 235 LLVDGGQHLLPLSRDVMFVAK 255 L VDGGQHL+PL+RDVMF+ + Sbjct: 251 LFVDGGQHLMPLARDVMFLTE 271 >ref|YP_001897646.1| short chain dehydrogenase [Ralstonia pickettii 12J] ref|ZP_07674891.1| oxidoreductase, short chain dehydrogenase/reductase family [Ralstonia sp. 5_7_47FAA] gb|ACD25214.1| short-chain dehydrogenase/reductase SDR [Ralstonia pickettii 12J] gb|EFP66489.1| oxidoreductase, short chain dehydrogenase/reductase family [Ralstonia sp. 5_7_47FAA] Length = 272 Score = 313 bits (802), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 164/251 (65%), Positives = 194/251 (77%), Gaps = 4/251 (1%) Query: 9 IALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIQALGRRALAVQAELGD 68 IALVTGA RR+GR IALALA+ GWDVAVH +RSR EAD + EI A+GRRA +QA+L D Sbjct: 22 IALVTGAGRRVGRVIALALARHGWDVAVHCHRSRTEADAVAAEITAMGRRAAVLQADLSD 81 Query: 69 ETQVRSLLPQ-AAPLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLAQALY 127 E L+ +A LG +C+VNNASLF YD A SF L HM NV AP+LL++ L+ Sbjct: 82 EAAAGRLIADCSAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRTNVAAPLLLSRELH 141 Query: 128 EA-TPPG--QQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVA 184 A T G + VVINLLDQKL N NPDFLSYTLSKAAL +AT LAQALAP +RVVGVA Sbjct: 142 RALTADGAEHRGVVINLLDQKLDNLNPDFLSYTLSKAALSTATMQLAQALAPALRVVGVA 201 Query: 185 PGLTMVSGDQTEEQFGKAHQVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHLL 244 PG+TMVSGDQ++ F +AHQ+TPLG+ STPEDIA AVCY+A+ARAVTGTTL VDGGQHL+ Sbjct: 202 PGITMVSGDQSQGGFARAHQMTPLGQSSTPEDIAEAVCYLATARAVTGTTLFVDGGQHLM 261 Query: 245 PLSRDVMFVAK 255 PL+RDVMF+ + Sbjct: 262 PLARDVMFLTE 272