BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0014.p (210 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777708.1| TetR family transcription regulator protein ... 425 e-117 ref|YP_003048531.1| TetR family transcriptional regulator [Methy... 174 5e-42 ref|ZP_02465384.1| transcriptional regulator, TetR family protei... 166 3e-39 ref|YP_003395103.1| TetR family transcriptional regulator [Conex... 164 1e-38 ref|YP_001619463.1| TetR family transcriptional regulator [Soran... 162 2e-38 ref|ZP_08875872.1| TetR family transcriptional regulator [Saccha... 159 4e-37 ref|YP_633362.1| transcriptional regulator SocA3 [Myxococcus xan... 158 4e-37 ref|ZP_07276420.1| transcriptional regulator [Streptomyces sp. A... 158 5e-37 ref|YP_373847.1| TetR family transcriptional regulator [Burkhold... 158 6e-37 gb|EFV82965.1| transcriptional regulator [Achromobacter xylosoxi... 157 7e-37 >ref|YP_003777708.1| TetR family transcription regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ65800.1| TetR family transcription regulator protein [Herbaspirillum seropedicae SmR1] Length = 210 Score = 425 bits (1092), Expect = e-117, Method: Compositional matrix adjust. Identities = 209/210 (99%), Positives = 210/210 (100%) Query: 1 MIRTRGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFR 60 MIRTRGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFR Sbjct: 1 MIRTRGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFR 60 Query: 61 EVVEVYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISA 120 EVVEVYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISA Sbjct: 61 EVVEVYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISA 120 Query: 121 INCAPENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLAL 180 INCAPENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLAL Sbjct: 121 INCAPENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLAL 180 Query: 181 GARDGVSSARLAATLGPAMLPLESVLLGAR 210 GA+DGVSSARLAATLGPAMLPLESVLLGAR Sbjct: 181 GAKDGVSSARLAATLGPAMLPLESVLLGAR 210 >ref|YP_003048531.1| TetR family transcriptional regulator [Methylotenera mobilis JLW8] gb|ACT48004.1| transcriptional regulator, TetR family [Methylotenera mobilis JLW8] Length = 200 Score = 174 bits (442), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 82/201 (40%), Positives = 127/201 (63%), Gaps = 6/201 (2%) Query: 6 GRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVEV 65 GRPR+FDRD AL +AM +FW KGYEGTTM D+ IG KAPS+YAAFG+KD LF EVV + Sbjct: 5 GRPRTFDRDDALNKAMLIFWEKGYEGTTMTDIINVIGTKAPSVYAAFGNKDKLFNEVVNL 64 Query: 66 YARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCAP 125 YA + A PL+ L I + +++ L ++V +++ + P C+++ +A NC+P Sbjct: 65 YAEILKAGPLKALNDHSSIYDAIRSSLYSNVEIFTSSNN----PC--SCLIMTAANNCSP 118 Query: 126 ENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARDG 185 E+SEH L R + I R QA +G++ + A+ L ++Y +F++GLAL A+DG Sbjct: 119 EHSEHMSNLKNLRTNYKRAIEVRFQQAVADGQLISSANPQTLAEYYMTFVHGLALRAKDG 178 Query: 186 VSSARLAATLGPAMLPLESVL 206 V+ + L + A++ ++ +L Sbjct: 179 VNKSELLTSTDYALVTVKLML 199 >ref|ZP_02465384.1| transcriptional regulator, TetR family protein [Burkholderia thailandensis MSMB43] Length = 205 Score = 166 bits (419), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 87/201 (43%), Positives = 122/201 (60%), Gaps = 6/201 (2%) Query: 6 GRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVEV 65 GRPR FDRD AL++AM FW +GYEGT+M+DL E +G+ + +YAAFG K+ALF E V + Sbjct: 7 GRPREFDRDMALKRAMLAFWRRGYEGTSMSDLVEVMGIASARIYAAFGSKEALFHEAVTL 66 Query: 66 YARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCAP 125 Y + R L +R ++ MLR ++ Y+ + G P GCMVV +A NCA Sbjct: 67 YEQGDGGFADRALSEETDVRAAIERMLRDAIATYTKR----GHP--HGCMVVSAATNCAA 120 Query: 126 ENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARDG 185 EN + L+ R R I RL A +G++ D+ AL DFY + L+G+++ +RDG Sbjct: 121 ENEGVVEWLAAHRRARTQSIAERLRLATEQGQLAPGTDIKALADFYATQLHGISVQSRDG 180 Query: 186 VSSARLAATLGPAMLPLESVL 206 VS RL A++GPAM+PL L Sbjct: 181 VSKERLLASIGPAMMPLAMAL 201 >ref|YP_003395103.1| TetR family transcriptional regulator [Conexibacter woesei DSM 14684] gb|ADB51728.1| transcriptional regulator, TetR family [Conexibacter woesei DSM 14684] Length = 205 Score = 164 bits (414), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 85/202 (42%), Positives = 125/202 (61%), Gaps = 6/202 (2%) Query: 5 RGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVE 64 RGRPR+FDRD AL++AM+VFW +GYEG ++ADLT +G+ +PSLYAAFG K+ LFRE V Sbjct: 4 RGRPRTFDRDAALRRAMEVFWERGYEGVSLADLTTEMGIASPSLYAAFGSKEGLFREAVA 63 Query: 65 VYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCA 124 +Y R L R ++AMLR + Y T PG P GCMVV++A N + Sbjct: 64 LYGTLEGGATARALAVQSTARAAIEAMLRDNAAGY----TTPGRP--TGCMVVLAATNVS 117 Query: 125 PENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARD 184 P N D ++++R R ++RAR+ + +G++ + DV AL + + L+GL+ ARD Sbjct: 118 PANQGIGDFMAEQRRTAREDVRARIARGVADGDVGPETDVDALAAYVATVLHGLSFEARD 177 Query: 185 GVSSARLAATLGPAMLPLESVL 206 GVS L A + AM+ ++++ Sbjct: 178 GVSCDTLNAIVDRAMVTWDALV 199 >ref|YP_001619463.1| TetR family transcriptional regulator [Sorangium cellulosum 'So ce 56'] emb|CAN98983.1| transcriptional regulator, TetR family [Sorangium cellulosum 'So ce 56'] Length = 206 Score = 162 bits (411), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 92/205 (44%), Positives = 126/205 (61%), Gaps = 6/205 (2%) Query: 1 MIRTRGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFR 60 M+ RGRPRSFDRD AL++AM+VFW +GYEGT+++DLT A+G+ +PSLYAAFG K+ALFR Sbjct: 1 MMVGRGRPRSFDRDAALRRAMEVFWERGYEGTSLSDLTAAMGINSPSLYAAFGCKEALFR 60 Query: 61 EVVEVYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISA 120 E V +Y+ A R + R ++AMLR +V Y+ PG P+ GCM+V++A Sbjct: 61 EAVALYSEVEGAATNRAMSDEPTARRAVEAMLRGNVEGYA----APGKPS--GCMIVLAA 114 Query: 121 INCAPENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLAL 180 PEN L+ R + +R RL + EG++ A D AL FYT+ L GL+L Sbjct: 115 TLGTPENERVRAYLAGCRRAALDALRRRLDRGVVEGDVPAGTDTAALAAFYTTVLQGLSL 174 Query: 181 GARDGVSSARLAATLGPAMLPLESV 205 ARDG S L A + AM E++ Sbjct: 175 QARDGASREALQAIVDCAMAAWETL 199 >ref|ZP_08875872.1| TetR family transcriptional regulator [Saccharopolyspora spinosa NRRL 18395] Length = 212 Score = 159 bits (401), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 85/202 (42%), Positives = 121/202 (59%), Gaps = 6/202 (2%) Query: 5 RGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVE 64 RGRPRSFDR+ AL+ AM +FW +GYE +++DLT A+G+ +PSLYAAFG K+ALFRE + Sbjct: 4 RGRPRSFDREAALRTAMNLFWERGYEAASLSDLTGAMGISSPSLYAAFGSKEALFREAIG 63 Query: 65 VYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCA 124 +Y A R LQ R ++AMLR + Y ST +GCMVV++A NC Sbjct: 64 LYNSADEAVGERSLQRQPTARRAIEAMLRDNADAYVDPSTP------RGCMVVLAATNCT 117 Query: 125 PENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARD 184 PEN D L++ R +RARL + +G++ AD+ + FY + L GL++ ARD Sbjct: 118 PENGRIRDYLAECRRDDFRAVRARLDRGITDGDVPPGADLETIASFYLTVLQGLSIQARD 177 Query: 185 GVSSARLAATLGPAMLPLESVL 206 G S + A + AML + ++ Sbjct: 178 GSSRETMHAVIDCAMLAWDGMV 199 >ref|YP_633362.1| transcriptional regulator SocA3 [Myxococcus xanthus DK 1622] gb|ABF88556.1| transcriptional regulator SocA3 [Myxococcus xanthus DK 1622] Length = 194 Score = 158 bits (400), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 84/195 (43%), Positives = 124/195 (63%), Gaps = 6/195 (3%) Query: 6 GRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVEV 65 GRPR FDRD+AL +AM+VFW++GYEGT++ DL +A+GV PSLY+ FG K+ LFRE VE+ Sbjct: 2 GRPRGFDRDEALVEAMRVFWARGYEGTSIQDLVDAMGVNKPSLYSIFGCKEELFREAVEL 61 Query: 66 YARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCAP 125 Y R R L+ R ++ MLRA+ R Y+ S P +GCM+V+S++ +P Sbjct: 62 YDRLEGIHTTRSLEDAPSARAAVEEMLRANARAYTA-SDKP-----RGCMIVLSSLLGSP 115 Query: 126 ENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARDG 185 EN L++ R + ++ RL + +G++ A A+V L FYT+ L GL++ +RDG Sbjct: 116 ENERVRTFLAENRLRGERALKQRLERGILDGDLPASAEVGMLAAFYTTVLEGLSIQSRDG 175 Query: 186 VSSARLAATLGPAML 200 S+ +LAA + AML Sbjct: 176 ASAKKLAAIIDAAML 190 >ref|ZP_07276420.1| transcriptional regulator [Streptomyces sp. AA4] gb|EFL04789.1| transcriptional regulator [Streptomyces sp. AA4] Length = 214 Score = 158 bits (400), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 90/195 (46%), Positives = 120/195 (61%), Gaps = 6/195 (3%) Query: 5 RGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVE 64 RGRPR+FDR+ AL QAM VFW +GY+G ++A+LTEA+G+K PSLYAAFGDK+ALFRE +E Sbjct: 4 RGRPRAFDREHALTQAMLVFWERGYDGASLAELTEAMGIKPPSLYAAFGDKEALFREAIE 63 Query: 65 VYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCA 124 Y +R L R ++A+LR + Y PG P KGCMVV++A NC Sbjct: 64 HYQSVYGRHTMRALTEEPTARAAVEALLRDNACAY----VEPGHP--KGCMVVLAATNCT 117 Query: 125 PENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARD 184 P N+ L+ R + R+ +R RL + EG++ A D+ AL YT+ GL L ARD Sbjct: 118 PANASVWKFLAASRDEVRSRLRERLRRGVEEGDLAATVDIDALSALYTTVFYGLTLQARD 177 Query: 185 GVSSARLAATLGPAM 199 GVS L A + A+ Sbjct: 178 GVSLDSLMAVIDLAL 192 >ref|YP_373847.1| TetR family transcriptional regulator [Burkholderia sp. 383] gb|ABB13203.1| transcriptional regulator, TetR family [Burkholderia sp. 383] Length = 201 Score = 158 bits (399), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 85/197 (43%), Positives = 120/197 (60%), Gaps = 6/197 (3%) Query: 6 GRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVEV 65 GRPR FDRD AL++AM FW GYEGT+M+DL EA+G+ + +YAAFG K+ALF+E V + Sbjct: 3 GRPREFDRDMALKRAMLAFWRHGYEGTSMSDLVEAMGIASARIYAAFGSKEALFQEAVAL 62 Query: 66 YARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCAP 125 Y + R +R ++ MLR +V Y+ + G P GCMVV +A N + Sbjct: 63 YEQGEGGFADRAFAEETDVRAAVERMLRDAVAAYTRR----GQP--HGCMVVSAATNYSA 116 Query: 126 ENSEHSDALSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLALGARDG 185 EN + L+ R R I RL A +G++ D+ AL DFY + L+G+++ +RDG Sbjct: 117 ENEGVMEWLAAHRRARTQSIVERLQLAAEQGQLARGTDIKALADFYATQLHGISVQSRDG 176 Query: 186 VSSARLAATLGPAMLPL 202 VS RL A++GPAM+PL Sbjct: 177 VSKERLLASIGPAMMPL 193 >gb|EFV82965.1| transcriptional regulator [Achromobacter xylosoxidans C54] Length = 214 Score = 157 bits (398), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 90/205 (43%), Positives = 122/205 (59%), Gaps = 14/205 (6%) Query: 5 RGRPRSFDRDQALQQAMQVFWSKGYEGTTMADLTEAIGVKAPSLYAAFGDKDALFREVVE 64 RGRPR+FDR QAL++AM+VFWSKGYEG ++ DLT A+G+ +PSLY AFG K+ LFRE V+ Sbjct: 4 RGRPRNFDRAQALRKAMEVFWSKGYEGASLTDLTAAMGINSPSLYGAFGSKEGLFREAVQ 63 Query: 65 VYARTVSAEPLRLLQAGKGIREDLQAMLRASVRMYSGKSTVPGLPAGKGCMVVISAINCA 124 +Y T A R L AG RE + ML A+ + T PG P GC++V+ A Sbjct: 64 LYRDTDGAASRRALAAGATAREGVCGMLLAAAERF----TAPGAP--PGCLIVLG----A 113 Query: 125 PENSEHSDA----LSQRRHKRRNEIRARLLQAQREGEIRADADVTALGDFYTSFLNGLAL 180 P +E D L R + ++ I ARL A GE+ A AD+ L FYT+ L+G+++ Sbjct: 114 PSGAESHDGVGVFLGDNRREMQSRILARLTAAASAGELPAGADLKGLAAFYTTILHGMSI 173 Query: 181 GARDGVSSARLAATLGPAMLPLESV 205 ARDG S L A AM +++ Sbjct: 174 QARDGASRKTLQAVARQAMCAWDAL 198