BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0506.p (206 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774478.1| TetR family transcription regulator protein ... 417 e-115 ref|YP_293277.1| regulatory protein, TetR [Ralstonia eutropha JM... 275 4e-72 ref|YP_004847640.1| TetR family transcriptional regulator [Pseud... 259 2e-67 ref|ZP_03697361.1| transcriptional regulator, TetR family [Lutie... 258 4e-67 ref|NP_902893.1| transcription regulator, TetR family [Chromobac... 252 2e-65 ref|YP_002795326.1| transcription regulator, TetR Family [Lariba... 248 5e-64 ref|YP_001022887.1| TetR family transcriptional regulator [Methy... 157 1e-36 ref|ZP_08401385.1| TetR family transcriptional regulator [Rubriv... 155 3e-36 ref|YP_996561.1| TetR family transcriptional regulator [Verminep... 154 7e-36 ref|YP_521685.1| TetR family transcriptional regulator [Rhodofer... 150 8e-35 >ref|YP_003774478.1| TetR family transcription regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ62570.1| TetR family transcription regulator protein [Herbaspirillum seropedicae SmR1] Length = 206 Score = 417 bits (1073), Expect = e-115, Method: Compositional matrix adjust. Identities = 204/206 (99%), Positives = 205/206 (99%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 MSIFGKLSFKDQAFKLRENAILDAAT+VLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK Sbjct: 1 MSIFGKLSFKDQAFKLRENAILDAATSVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD Sbjct: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF Sbjct: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 Query: 181 SKMSNEDIIKYMLHVAFKGFEQDAPR 206 SKM NEDIIKYMLHVAFKGFEQDAPR Sbjct: 181 SKMGNEDIIKYMLHVAFKGFEQDAPR 206 >ref|YP_293277.1| regulatory protein, TetR [Ralstonia eutropha JMP134] gb|AAZ65420.1| regulatory protein, TetR [Ralstonia eutropha JMP134] Length = 204 Score = 275 bits (702), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 133/199 (66%), Positives = 159/199 (79%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 M I GKLSFKDQ F+LRE+AILDA T +L KG+DLMTMDDVAG VGISKP LYKHFKSK Sbjct: 1 MGILGKLSFKDQTFRLREDAILDATTRILADKGFDLMTMDDVAGEVGISKPILYKHFKSK 60 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 ++L+G MIRLIDGAID L QL A +L A+L WALRVRLEGGLPFLPSTS VR+ Sbjct: 61 DDLVGAAMIRLIDGAIDFLEQLPQQETAMGRLRALLAWALRVRLEGGLPFLPSTSPHVRE 120 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 ML N+ YV RV KLNG L+ LV EA+K+G+LDAALP DV+L+SYY+RTCDPAV+YL+ + Sbjct: 121 MLTHNLGYVTRVFKLNGILKGLVGEAKKSGDLDAALPDDVILFSYYSRTCDPAVEYLRLY 180 Query: 181 SKMSNEDIIKYMLHVAFKG 199 +K+ +E I+ +ML V F G Sbjct: 181 AKLDDERIVAHMLDVCFHG 199 >ref|YP_004847640.1| TetR family transcriptional regulator [Pseudogulbenkiania sp. NH8B] dbj|BAK77226.1| transcriptional regulator, TetR family [Pseudogulbenkiania sp. NH8B] Length = 203 Score = 259 bits (662), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 122/203 (60%), Positives = 159/203 (78%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 MSI KLSFKDQAFKLRE A+LDA T +L SKG+DLMTMDDVAG GISKPSLYKHFKSK Sbjct: 1 MSILSKLSFKDQAFKLREQAVLDATTKLLASKGFDLMTMDDVAGEAGISKPSLYKHFKSK 60 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 E+L E MIRL+DGA++ L L+ +++L ++LEWALRVRL+GGLPFLPS+S VR Sbjct: 61 EDLATEVMIRLLDGALEYLDGLDAGMSGKERLGSLLEWALRVRLQGGLPFLPSSSPQVRA 120 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 ML RN++YV RV +L+ QL+ +V +A+ AGE+ LP+DV+LY+YY+RTCDPAVDY++ + Sbjct: 121 MLTRNIRYVTRVYQLHKQLQGMVDKAKAAGEIRDDLPTDVILYAYYSRTCDPAVDYMKDY 180 Query: 181 SKMSNEDIIKYMLHVAFKGFEQD 203 S++DI+ +M + F G +D Sbjct: 181 GHYSDDDIVAHMRSMIFTGIAKD 203 >ref|ZP_03697361.1| transcriptional regulator, TetR family [Lutiella nitroferrum 2002] gb|EEG09847.1| transcriptional regulator, TetR family [Lutiella nitroferrum 2002] Length = 203 Score = 258 bits (658), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 121/203 (59%), Positives = 159/203 (78%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 MSI KLSFKDQAFKLRE A+LDA T +L SKG+DLMTMDDVAG GISKPSLYKHFKSK Sbjct: 1 MSILSKLSFKDQAFKLREQAVLDATTKLLASKGFDLMTMDDVAGEAGISKPSLYKHFKSK 60 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 E+L E MIRL+DGA++ L L+ +++L ++LEWALRVRL+GGLPFLPS+S VR Sbjct: 61 EDLATEVMIRLLDGALEYLDGLDAGMSGKERLGSLLEWALRVRLQGGLPFLPSSSPQVRA 120 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 ML RN++YV RV +L+ QL+ +V +++ AGE+ LP+DV+LY+YY+RTCDPAVDY++ + Sbjct: 121 MLTRNIRYVTRVYQLHKQLQGMVDKSKAAGEIRDDLPTDVILYAYYSRTCDPAVDYMKDY 180 Query: 181 SKMSNEDIIKYMLHVAFKGFEQD 203 S++DI+ +M + F G +D Sbjct: 181 GHYSDDDIVAHMRTMIFTGIAKD 203 >ref|NP_902893.1| transcription regulator, TetR family [Chromobacterium violaceum ATCC 12472] gb|AAQ60889.1| probable transcription regulator, TetR Family [Chromobacterium violaceum ATCC 12472] Length = 211 Score = 252 bits (643), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 122/199 (61%), Positives = 153/199 (76%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 M I G+LSFKDQAFKLRE A+LDA T +L SKG+DLMTMDDVAG GISKPSLYKHFKSK Sbjct: 1 MGILGRLSFKDQAFKLREQAVLDATTRMLASKGFDLMTMDDVAGEAGISKPSLYKHFKSK 60 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 +EL E MIRL+D A D LA+ +L +L WALRVRLEGGLPFLPS S VR Sbjct: 61 DELATEVMIRLLDDAQDFLARQAPELSPLARLRDLLAWALRVRLEGGLPFLPSASPQVRA 120 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 ML R+++YV R +KL+ L+ +V++A++ GEL A +P+DV+LYSYY+RTCDPAV+YL+ + Sbjct: 121 MLTRSLRYVSRAIKLHKTLQGIVEQAKRQGELRADMPTDVILYSYYSRTCDPAVEYLRVY 180 Query: 181 SKMSNEDIIKYMLHVAFKG 199 K +EDI+++ML V F G Sbjct: 181 GKYPDEDIVRHMLEVCFDG 199 >ref|YP_002795326.1| transcription regulator, TetR Family [Laribacter hongkongensis HLHK9] gb|ACO74317.1| Probable transcription regulator, TetR Family [Laribacter hongkongensis HLHK9] Length = 203 Score = 248 bits (632), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 113/200 (56%), Positives = 153/200 (76%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 MSI G+LSFKDQAF+LRE A+LDA T +L SKG+DLMTMDDVA G+SKPSLYKHF+SK Sbjct: 1 MSIMGRLSFKDQAFRLREQAVLDATTTLLASKGFDLMTMDDVAEGAGLSKPSLYKHFRSK 60 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 E L E MIRL+D A++ L + + + +L+ ++EWALR RLEGGLPFLPSTS VRD Sbjct: 61 EALATEVMIRLLDRALEHLDAQDPVMDGKARLDNLMEWALRTRLEGGLPFLPSTSPHVRD 120 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 MLM +V+Y +R+ +L+ QL++LV++A+ G + LP+DV+LY+YY+RTCDPAVDY++ F Sbjct: 121 MLMHSVRYSLRIYRLHTQLQQLVEQARTEGSIRNDLPTDVLLYAYYSRTCDPAVDYMKDF 180 Query: 181 SKMSNEDIIKYMLHVAFKGF 200 + +++II M + F G Sbjct: 181 GRYDDDEIIACMRSIMFSGI 200 >ref|YP_001022887.1| TetR family transcriptional regulator [Methylibium petroleiphilum PM1] gb|ABM96652.1| transcriptional regulator, TetR family [Methylibium petroleiphilum PM1] Length = 204 Score = 157 bits (396), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 81/203 (39%), Positives = 128/203 (63%), Gaps = 10/203 (4%) Query: 4 FGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSKEEL 63 K SF++Q + RE+AI+ + +L KG++ MT+D+VA VGI+K SLYKHF SKEEL Sbjct: 1 MAKTSFREQMLRAREDAIVSSVNRLLAEKGFEAMTVDEVAADVGIAKASLYKHFTSKEEL 60 Query: 64 IGETMIRLIDGAI---DQLA---QLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAP 117 M+R+++ A+ + LA QL IA +LEA+ W L V+L G +P LP+ ++ Sbjct: 61 AAAAMVRVLERALAFTEILATDDQLRPIA----RLEAVARWTLEVQLAGEMPSLPAQNST 116 Query: 118 VRDMLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYL 177 +R+ LM N Y+ R+ +++ +L + AQ GE+D LP++VVLY+ +AR CDP + L Sbjct: 117 LRNALMANRGYLDRLFEVSDRLGAWITAAQADGEIDRQLPAEVVLYTLFARACDPVLGLL 176 Query: 178 QKFSKMSNEDIIKYMLHVAFKGF 200 + + S+ II+++L F+G Sbjct: 177 KAGGQHSDAQIIEWLLRTCFRGL 199 >ref|ZP_08401385.1| TetR family transcriptional regulator [Rubrivivax benzoatilyticus JA2] gb|EGJ09718.1| TetR family transcriptional regulator [Rubrivivax benzoatilyticus JA2] Length = 202 Score = 155 bits (392), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 76/201 (37%), Positives = 127/201 (63%), Gaps = 1/201 (0%) Query: 4 FGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSKEEL 63 +LSF++Q ++RE+AI+ + +L KG+DLMT+D+VA VGI+K SLYKHF SKE L Sbjct: 1 MARLSFREQVLRVREDAIVASVNRLLAEKGFDLMTVDEVAADVGIAKASLYKHFPSKEAL 60 Query: 64 IGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRDMLM 123 M+RL++ + + + A D+L ++ WAL +++ G +P LPS ++ +R L+ Sbjct: 61 AAAAMVRLLEQT-HSIVESQDAERAIDRLASVTRWALHLQIAGEMPSLPSQNSTLRAELL 119 Query: 124 RNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKFSKM 183 N YV +++++ +L + + +AQ G++D ALP +V LY+ +AR CDP YL+ + Sbjct: 120 ANKAYVDLLMEVSDRLGEWIVQAQADGDIDPALPPEVALYTIFARACDPVPAYLKAGGRY 179 Query: 184 SNEDIIKYMLHVAFKGFEQDA 204 S+E I++++L V G A Sbjct: 180 SDEQIVEWVLAVCMNGLRPRA 200 >ref|YP_996561.1| TetR family transcriptional regulator [Verminephrobacter eiseniae EF01-2] gb|ABM57543.1| transcriptional regulator, TetR family [Verminephrobacter eiseniae EF01-2] Length = 210 Score = 154 bits (389), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 83/200 (41%), Positives = 119/200 (59%) Query: 1 MSIFGKLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSK 60 +++ K+SFK Q ++ RE AIL +A +LG K +DLMTMDDVA AVGI+K SLYKHF SK Sbjct: 8 LTVPPKVSFKAQMYQAREAAILASACRLLGEKAFDLMTMDDVANAVGIAKASLYKHFGSK 67 Query: 61 EELIGETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRD 120 E L M++++ LA L A +KL A+L W+L L +P LP + +R Sbjct: 68 EALCTAAMVQMLGRVQTYLASLPAQTPALEKLHALLRWSLEQLLGNQMPLLPGRHSGLRA 127 Query: 121 MLMRNVKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKF 180 +LM N Y + L+ Q+ + EAQ G +D LP VV Y+ YAR CDPA+ L++ Sbjct: 128 VLMANQDYRAGLRALSEQIGAWITEAQAQGLIDPGLPLVVVQYTLYARACDPALCLLKEG 187 Query: 181 SKMSNEDIIKYMLHVAFKGF 200 + S+ +I++ +L F G Sbjct: 188 GQYSDAEIVELVLRTCFDGL 207 >ref|YP_521685.1| TetR family transcriptional regulator [Rhodoferax ferrireducens T118] gb|ABD68154.1| transcriptional regulator, TetR family [Rhodoferax ferrireducens T118] Length = 205 Score = 150 bits (380), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 77/195 (39%), Positives = 118/195 (60%) Query: 6 KLSFKDQAFKLRENAILDAATAVLGSKGYDLMTMDDVAGAVGISKPSLYKHFKSKEELIG 65 + SFK Q + RE AI+ A +L KG++ MT+D+VA GI+K SLYKHF SKEEL Sbjct: 8 RTSFKQQMLQAREEAIIQTANRLLAEKGFEAMTVDEVALQAGIAKASLYKHFASKEELAA 67 Query: 66 ETMIRLIDGAIDQLAQLEHIAGARDKLEAMLEWALRVRLEGGLPFLPSTSAPVRDMLMRN 125 R++ A D + L A DKL A+L W L V+L G +P LPS ++ +R L+ N Sbjct: 68 AATARVMRRARDFIRALPEQAPPLDKLRAVLRWTLEVKLAGDMPSLPSRNSTLRTALIGN 127 Query: 126 VKYVMRVLKLNGQLEKLVKEAQKAGELDAALPSDVVLYSYYARTCDPAVDYLQKFSKMSN 185 + ++++ +L ++ AQ AG L+ ALP+ VLY+++AR CDPA+++L+ + + Sbjct: 128 QDCMEGWMEVSDRLRAWIEAAQAAGALNPALPAVAVLYTFFARACDPALEFLRIGGRYQD 187 Query: 186 EDIIKYMLHVAFKGF 200 E I+ +L F+G Sbjct: 188 EQIVTLVLSTCFEGL 202