BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0451.p (209 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774526.1| 2-keto-4-hydroxyglutarate aldolase/-keto-3-d... 409 e-112 ref|YP_004752110.1| 4-Hydroxy-2-oxoglutarate aldolase [Collimona... 330 6e-89 emb|CAL61266.2| bifunctional KHG/KDPG aldolase [Includes: 4-hydr... 327 8e-88 ref|ZP_08274008.1| 4-Hydroxy-2-oxoglutarate aldolase [Oxalobacte... 322 3e-86 ref|YP_001354000.1| 2-dehydro-3-deoxyphosphogluconate aldolase [... 318 3e-85 ref|YP_001099393.1| 4-hydroxy-2-oxoglutarate aldolase / 2-dehydr... 306 1e-81 ref|ZP_04720967.1| keto-hydroxyglutarate-aldolase/keto-deoxy-pho... 235 4e-60 ref|ZP_06569421.1| keto-hydroxyglutarate-aldolase/keto-deoxy-pho... 235 4e-60 ref|ZP_06149119.1| keto-hydroxyglutarate-aldolase/keto-deoxy-pho... 234 5e-60 ref|ZP_06130903.1| keto-hydroxyglutarate-aldolase/keto-deoxy-pho... 234 7e-60 >ref|YP_003774526.1| 2-keto-4-hydroxyglutarate aldolase/-keto-3-deoxy-6-phosphogluconate aldolase [Herbaspirillum seropedicae SmR1] gb|ADJ62618.1| 2-keto-4-hydroxyglutarate aldolase/-keto-3-deoxy-6-phosphogluconate aldolase protein [Herbaspirillum seropedicae SmR1] Length = 209 Score = 409 bits (1052), Expect = e-112, Method: Compositional matrix adjust. Identities = 208/208 (100%), Positives = 208/208 (100%) Query: 1 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV 60 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV Sbjct: 1 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV 60 Query: 61 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA 120 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA Sbjct: 61 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA 120 Query: 121 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS 180 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS Sbjct: 121 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS 180 Query: 181 WLTPKAAIEAGDWDKITEIAKAASALKK 208 WLTPKAAIEAGDWDKITEIAKAASALKK Sbjct: 181 WLTPKAAIEAGDWDKITEIAKAASALKK 208 >ref|YP_004752110.1| 4-Hydroxy-2-oxoglutarate aldolase [Collimonas fungivorans Ter331] gb|AEK61287.1| 4-Hydroxy-2-oxoglutarate aldolase [Collimonas fungivorans Ter331] Length = 203 Score = 330 bits (847), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 169/202 (83%), Positives = 181/202 (89%) Query: 8 MRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPDAIVGV 67 MRASPVIPVIAID EHAVPLA+ALVAGGIRVLE+TLRT HGLPAIRAIAE VP AIVGV Sbjct: 1 MRASPVIPVIAIDDIEHAVPLAKALVAGGIRVLEVTLRTAHGLPAIRAIAEQVPGAIVGV 60 Query: 68 GTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAAREAGFRQ 127 GTLT +EF A+RDAGAVFGVSPGLTPALI AAK SGLPLLPGVMTPSEVMAAREAGFRQ Sbjct: 61 GTLTQADEFVAARDAGAVFGVSPGLTPALIAAAKSSGLPLLPGVMTPSEVMAAREAGFRQ 120 Query: 128 LKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWLTPKAA 187 LKLFPAVPAGGVGMLN IAGPL DV+FCPTGGI+ ETAP FLACKNV CVGGSWLTPK Sbjct: 121 LKLFPAVPAGGVGMLNAIAGPLGDVTFCPTGGISLETAPDFLACKNVACVGGSWLTPKDV 180 Query: 188 IEAGDWDKITEIAKAASALKKA 209 +++GDW +IT +A AAS L+KA Sbjct: 181 LKSGDWARITALAAAASKLRKA 202 >emb|CAL61266.2| bifunctional KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase) (Phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)] [Herminiimonas arsenicoxydans] Length = 206 Score = 327 bits (837), Expect = 8e-88, Method: Compositional matrix adjust. Identities = 162/203 (79%), Positives = 179/203 (88%) Query: 5 LEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPDAI 64 LEIMR SPVIPVIAID HAVPLARALVAGGIRVLE+TLRT++GL AIR IAE VP+AI Sbjct: 4 LEIMRCSPVIPVIAIDDLSHAVPLARALVAGGIRVLEVTLRTQYGLAAIREIAEQVPEAI 63 Query: 65 VGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAAREAG 124 +GVGTLT E+F A+RDAGA+FGVSPGLT LIE A+ SGLPLLPGVMTPSEVM AREAG Sbjct: 64 LGVGTLTRHEDFAAARDAGAIFGVSPGLTKELIEGARSSGLPLLPGVMTPSEVMRAREAG 123 Query: 125 FRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWLTP 184 FRQ+KLFPAVPAGGVGMLN IAGPL D+ FCPTGGI+QETA QFLACKNV CVGGSWLTP Sbjct: 124 FRQVKLFPAVPAGGVGMLNAIAGPLPDMLFCPTGGISQETAAQFLACKNVACVGGSWLTP 183 Query: 185 KAAIEAGDWDKITEIAKAASALK 207 K A+ AGDW ++T +AKAASAL+ Sbjct: 184 KDALAAGDWARVTALAKAASALR 206 >ref|ZP_08274008.1| 4-Hydroxy-2-oxoglutarate aldolase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32528.1| 4-Hydroxy-2-oxoglutarate aldolase [Oxalobacteraceae bacterium IMCC9480] Length = 220 Score = 322 bits (824), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 163/197 (82%), Positives = 172/197 (87%) Query: 1 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV 60 M L IMR SPVIPVIAID +HAVPLARALVAGGIRVLE+TLRT HGL AIRAIA V Sbjct: 12 MPDLLHIMRVSPVIPVIAIDDLDHAVPLARALVAGGIRVLEVTLRTVHGLAAIRAIAGQV 71 Query: 61 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA 120 PDAI+GVGTLT PEEF A+RDAGAVFGVSPGLTPALI AA+ SGLPLLPGVMTPSEVMAA Sbjct: 72 PDAILGVGTLTLPEEFAAARDAGAVFGVSPGLTPALIAAARSSGLPLLPGVMTPSEVMAA 131 Query: 121 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS 180 REAGFRQLKLFPAVPAGGVGML IAGPL DV FCPTGGI+ TAPQFLACKNV CVGGS Sbjct: 132 REAGFRQLKLFPAVPAGGVGMLGAIAGPLGDVMFCPTGGISLATAPQFLACKNVACVGGS 191 Query: 181 WLTPKAAIEAGDWDKIT 197 WLTPK A+ +GDW +IT Sbjct: 192 WLTPKDAMLSGDWARIT 208 >ref|YP_001354000.1| 2-dehydro-3-deoxyphosphogluconate aldolase [Janthinobacterium sp. Marseille] gb|ABR89009.1| 2-dehydro-3-deoxyphosphogluconate aldolase [Janthinobacterium sp. Marseille] Length = 206 Score = 318 bits (815), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 159/193 (82%), Positives = 171/193 (88%) Query: 5 LEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPDAI 64 LEIMRASPVIPVIAID HAVPLARALVAGGIRVLE+TLRT+HGL AIRAIAE VP+AI Sbjct: 4 LEIMRASPVIPVIAIDDLTHAVPLARALVAGGIRVLEVTLRTQHGLAAIRAIAEQVPEAI 63 Query: 65 VGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAAREAG 124 +GVGTLT E+F A+RDAGAVFGVSPGLT LI+ + SGLPLLPGVMTPSEVMAAREAG Sbjct: 64 LGVGTLTRSEDFAAARDAGAVFGVSPGLTRELIQGSLASGLPLLPGVMTPSEVMAAREAG 123 Query: 125 FRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWLTP 184 F QLKLFPAVPAGGVGMLN IAGPL DV FCPTGGI+QETA QFLACKNV CVGGSWLTP Sbjct: 124 FHQLKLFPAVPAGGVGMLNAIAGPLPDVLFCPTGGISQETAAQFLACKNVACVGGSWLTP 183 Query: 185 KAAIEAGDWDKIT 197 K A+ AGDW ++T Sbjct: 184 KDALAAGDWGRVT 196 >ref|YP_001099393.1| 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [Herminiimonas arsenicoxydans] Length = 192 Score = 306 bits (784), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 151/192 (78%), Positives = 169/192 (88%) Query: 16 VIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPDAIVGVGTLTSPEE 75 +IAID HAVPLARALVAGGIRVLE+TLRT++GL AIR IAE VP+AI+GVGTLT E+ Sbjct: 1 MIAIDDLSHAVPLARALVAGGIRVLEVTLRTQYGLAAIREIAEQVPEAILGVGTLTRHED 60 Query: 76 FTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAAREAGFRQLKLFPAVP 135 F A+RDAGA+FGVSPGLT LIE A+ SGLPLLPGVMTPSEVM AREAGFRQ+KLFPAVP Sbjct: 61 FAAARDAGAIFGVSPGLTKELIEGARSSGLPLLPGVMTPSEVMRAREAGFRQVKLFPAVP 120 Query: 136 AGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWLTPKAAIEAGDWDK 195 AGGVGMLN IAGPL D+ FCPTGGI+QETA QFLACKNV CVGGSWLTPK A+ AGDW + Sbjct: 121 AGGVGMLNAIAGPLPDMLFCPTGGISQETAAQFLACKNVACVGGSWLTPKDALAAGDWAR 180 Query: 196 ITEIAKAASALK 207 +T +AKAASAL+ Sbjct: 181 VTALAKAASALR 192 >ref|ZP_04720967.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae DGI18] ref|ZP_04723029.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae FA6140] ref|ZP_04734580.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae PID24-1] ref|ZP_05106996.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae 1291] gb|EEH62210.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae 1291] Length = 212 Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 123/205 (60%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 5 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 64 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AIVG GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 65 AIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 124 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 125 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 184 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 185 TPKEAVKNKDWDTITRLAKEAAALK 209 >ref|ZP_06569421.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae DGI2] ref|ZP_06643162.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Neisseria gonorrhoeae F62] gb|EFE04157.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae DGI2] gb|EFF39521.1| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Neisseria gonorrhoeae F62] Length = 226 Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 123/205 (60%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 19 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 78 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AIVG GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 79 AIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 138 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 139 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 198 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 199 TPKEAVKNKDWDTITRLAKEAAALK 223 >ref|ZP_06149119.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae PID332] ref|ZP_06153586.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae SK-93-1035] gb|EEZ54941.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae PID332] gb|EEZ59408.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae SK-93-1035] Length = 212 Score = 234 bits (597), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 122/205 (59%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 5 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 64 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AI+G GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 65 AIIGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 124 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 125 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 184 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 185 TPKEAVKNKDWDTITRLAKEAAALK 209 >ref|ZP_06130903.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae FA19] gb|EEZ45543.1| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Neisseria gonorrhoeae FA19] Length = 226 Score = 234 bits (597), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 122/205 (59%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 19 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 78 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AI+G GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 79 AIIGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 138 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 139 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 198 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 199 TPKEAVKNKDWDTITRLAKEAAALK 223