BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0197.p (605 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773735.1| adenylate cyclase [Herbaspirillum seropedica... 1149 0.0 ref|ZP_01915752.1| adenylate/guanylate cyclase [Limnobacter sp. ... 531 e-148 gb|EGW60103.1| adenylate/guanylate cyclase with Chase sensor [De... 462 e-128 emb|CBA30925.1| hypothetical protein Csp_C25990 [Curvibacter put... 456 e-126 ref|YP_004158173.1| adenylate/guanylate cyclase with chase senso... 445 e-122 ref|ZP_08505392.1| Adenylate/guanylate cyclase with Chase sensor... 437 e-120 ref|YP_002947055.1| adenylate/guanylate cyclase with Chase senso... 436 e-120 ref|YP_003523160.1| adenylate/guanylate cyclase with Chase senso... 431 e-118 ref|YP_546237.1| adenylate/guanylate cyclase [Methylobacillus fl... 410 e-112 ref|ZP_05062227.1| adenylate/guanylate cyclase [gamma proteobact... 409 e-111 >ref|YP_003773735.1| adenylate cyclase [Herbaspirillum seropedicae SmR1] gb|ADJ61827.1| adenylate cyclase protein [Herbaspirillum seropedicae SmR1] Length = 757 Score = 1149 bits (2973), Expect = 0.0, Method: Compositional matrix adjust. Identities = 571/575 (99%), Positives = 573/575 (99%) Query: 12 MLRRLRTAFATYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQPDLDP 71 MLRRLRTAFATYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQPDLDP Sbjct: 1 MLRRLRTAFATYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQPDLDP 60 Query: 72 RIVIVDIDEKSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLA 131 RIVIVDIDEKSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLA Sbjct: 61 RIVIVDIDEKSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLA 120 Query: 132 QLADGPLKDVPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPP 191 QLADGPLKDVPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPP Sbjct: 121 QLADGPLKDVPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPP 180 Query: 192 AFSVADLGGRALDVTHWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHF 251 AFSVADLGGRALDVTHWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHF Sbjct: 181 AFSVADLGGRALDVTHWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHF 240 Query: 252 YESLALATARVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHL 311 YESLALATARVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHL Sbjct: 241 YESLALATARVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHL 300 Query: 312 TTLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPV 371 TTLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPV Sbjct: 301 TTLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPV 360 Query: 372 YPGVEIHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLAT 431 YPGVEIHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLAT Sbjct: 361 YPGVEIHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLAT 420 Query: 432 AAGLGGLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAP 491 AAGLGGLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAP Sbjct: 421 AAGLGGLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAP 480 Query: 492 ELVAEMAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIR 551 ELVAEMAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIR Sbjct: 481 ELVAEMAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIR 540 Query: 552 GNRGTLDKYIGDAVMAFWGAPLALPDHAARAXNSS 586 GNRGTLDKYIGDAVMAFWGAPLALPDHAARA ++ Sbjct: 541 GNRGTLDKYIGDAVMAFWGAPLALPDHAARAVATA 575 >ref|ZP_01915752.1| adenylate/guanylate cyclase [Limnobacter sp. MED105] gb|EDM82997.1| adenylate/guanylate cyclase [Limnobacter sp. MED105] Length = 754 Score = 531 bits (1367), Expect = e-148, Method: Compositional matrix adjust. Identities = 288/560 (51%), Positives = 391/560 (69%), Gaps = 19/560 (3%) Query: 33 LTGLATAQVMALLPNRLVERMDLFFYDLRMRV-AQ-PDLDPRIVIVDIDEKSIAELGRWP 90 T +A V+ P+ +V+R+D YD+R+R AQ P+LDPRIVIVDIDE+S++E+GRWP Sbjct: 24 FTAVALLHVLGFAPSEVVKRLDYLVYDVRLRAEAQLPELDPRIVIVDIDEQSLSEVGRWP 83 Query: 91 WSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKDVPQFARQLQA 150 WSRDV+A+LV ++T A +VGFD+VFAEP S L D +++ P QLQ Sbjct: 84 WSRDVVAKLVVELTDRLGAAAVGFDIVFAEPQQSDALLAL----DTIIENKPALGSQLQE 139 Query: 151 LKP----QMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPPAFSVADLGGRALDVT 206 ++ Q D DA+LA+ L +PVV+GY L+ +A A++ G LPP F + LG +LD T Sbjct: 140 MRSGIQAQFDRDAQLAQVLADRPVVLGYYLNQDATALS-GALPPALFKKSQLGELSLDST 198 Query: 207 HWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHFYESLALATARVALDG 266 W+ YG N+P LQ A GG+FNP+ D+DG +R++PL+AQ + +Y+S AL T R AL Sbjct: 199 SWQGYGGNIPVLQKNAE-GGYFNPIVDEDGTVRSIPLIAQFNDAYYQSFALGTLRRALGN 257 Query: 267 RRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHLTTLVSYRGKGGPNGG 326 ++ P+F EG DYGA+ IA+ + L IPVER L T V +R KGGPN G Sbjct: 258 PQVIPVFP-------EGVPDDYGAVELIALRSPEVELDIPVERGLLTRVHFRAKGGPNAG 310 Query: 327 AFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPVYPGVEIHANLIASII 386 +RYV A DV+ G ++GRI+L+GTT PGL DLR+TPVNP YPGVE+HAN+I+ ++ Sbjct: 311 GYRYVSAADVLAGALKPEDIEGRIVLIGTTAPGLLDLRSTPVNPAYPGVEVHANVISGML 370 Query: 387 DGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLATAAGLGGLNFWLYDSA 446 D +K RP+++ G + VLAVG +L +++P+L WS+++ LA +N LY A Sbjct: 371 DSIYKLRPEYSQGLLFITVLAVGFVLSVMMPILSATWSLLVALAVLVASVAINSVLYFQA 430 Query: 447 GMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAPELVAEMAANPASYNM 506 G+VLP+A LLLV ++F+ ++ +GYL E R+++ +V+LFGEYVAPELV+EMA++P Y+M Sbjct: 431 GLVLPVAVVLLLVLAIFMFDVAYGYLAESRSKRQMVDLFGEYVAPELVSEMASDPTRYSM 490 Query: 507 EGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIRGNRGTLDKYIGDAVM 566 EGE RELTV+FSDVRGFTTISESLQPNELREYIN YLT MSE IR +RGTLDKYIGDA+M Sbjct: 491 EGESRELTVLFSDVRGFTTISESLQPNELREYINEYLTVMSEIIRSHRGTLDKYIGDAIM 550 Query: 567 AFWGAPLALPDHAARAXNSS 586 AFWGAP+A +HA A ++ Sbjct: 551 AFWGAPIADAEHAELATKAA 570 >gb|EGW60103.1| adenylate/guanylate cyclase with Chase sensor [Dechlorosoma suillum PS] Length = 737 Score = 462 bits (1190), Expect = e-128, Method: Compositional matrix adjust. Identities = 266/540 (49%), Positives = 351/540 (65%), Gaps = 15/540 (2%) Query: 44 LLPNRLVERMDLFFYDLRMRVAQPD-LDPRIVIVDIDEKSIAELGRWPWSRDVIAQLVRQ 102 L + L+ +D YD R+R+ QP D R+V+VDIDEKS+AE+GRWPWSRD +++LV+Q Sbjct: 25 LYQHPLLSHLDAITYDARLRLTQPGGQDSRVVVVDIDEKSLAEVGRWPWSRDKVSRLVQQ 84 Query: 103 MTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKDVPQFARQLQALKPQMDYDARLA 162 +T Y Q VGFDVVFAEPD SSG L ++ LK F L +L+ +DYD + A Sbjct: 85 LTDHYGVQLVGFDVVFAEPDESSGLRVLERMGATSLKGDAAFLASLSSLRGSLDYDGQFA 144 Query: 163 EALRGQPVVMGYNLSNEAGAIAKGQLPPPAFSVADLGGRALDVTHWRAYGANLPQLQAAA 222 L+G+PVV+G+ +SN I +G LPP GR + T WR YG NLP QAAA Sbjct: 145 ATLKGRPVVLGFYMSN---GIPQGALPPAVLPAGTFQGRNILFTSWRGYGGNLPAFQAAA 201 Query: 223 RAGGFFNPVPDDDGLIRAVPLMAQVGEHFYESLALATARVALDGRRIKPIFLQRQDVLFE 282 AGG FNP+ D DG+ R VP++ + G +YESL+LA R+ L ++P + + Sbjct: 202 PAGGHFNPLVDFDGISRRVPMLVEHGGQYYESLSLAMVRLLLGNVPVRPGYAEGGGGSGY 261 Query: 283 GQLRDYGALAGIAVETRPQPLFIPVERHLTTLVSYRGKGGPNGGAFRYVPAVDVIRGTYP 342 L + + T L IPV+ ++ TLV YRG G+F Y+ A DV++G Sbjct: 262 AGLE------WLDLPTPRGALRIPVDENVATLVPYRG----GQGSFVYLSAADVLQGRVA 311 Query: 343 HAQLDGRIMLVGTTVPGLNDLRATPVNPVYPGVEIHANLIASIIDGDFKARPDFAVGYDL 402 A L G+++LVGTT PGL DLRATPV YPGVEIHANLIA ++DG K +P +A+G+D+ Sbjct: 312 PASLQGKVVLVGTTAPGLMDLRATPVGEAYPGVEIHANLIAGMLDGSLKHKPPYALGFDV 371 Query: 403 LQVLAVGVLLGLLLPMLGPLWSIVLTLATAAGLGGLNFWLYDSAGMVLPLATALLLVASL 462 +QVL VG+LL LLLP L P + +LT A AG+ GLN L+ S G+ LP+A LLL+ +L Sbjct: 372 VQVLLVGLLLSLLLPSLSPSRATLLTGAVLAGVVGLNLALWQS-GLALPVAGVLLLILAL 430 Query: 463 FICNLGWGYLFEYRNRKAIVNLFGEYVAPELVAEMAANPASYNMEGEIRELTVMFSDVRG 522 + N+ WGY E +++ + LFG+YV PELV EMA +P Y+MEG ELTV+FSD+RG Sbjct: 431 YAMNMSWGYFVESHSKRQLTQLFGQYVPPELVDEMARDPERYSMEGRNAELTVLFSDIRG 490 Query: 523 FTTISESLQPNELREYINVYLTAMSEDIRGNRGTLDKYIGDAVMAFWGAPLALPDHAARA 582 FT+ISE L P +L IN YL AM+ IR +RGTLDKYIGDA+MAFWGAP+A PDHA A Sbjct: 491 FTSISEGLDPKDLAHLINEYLGAMTTVIRHHRGTLDKYIGDAIMAFWGAPVADPDHARHA 550 >emb|CBA30925.1| hypothetical protein Csp_C25990 [Curvibacter putative symbiont of Hydra magnipapillata] Length = 749 Score = 456 bits (1172), Expect = e-126, Method: Compositional matrix adjust. Identities = 233/565 (41%), Positives = 347/565 (61%), Gaps = 6/565 (1%) Query: 23 YWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQP-DLDPRIVIVDIDEK 81 +W R + L+ A + +L +++R+D YD R+R P +D RIVIVDIDEK Sbjct: 7 HWPRIAVTLIPLIFALLHAVGVLQLSVLQRLDDIIYDTRLRATMPKSMDERIVIVDIDEK 66 Query: 82 SIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKDV 141 S+A +GRWPW R+ +A LV ++ ++ +G DVVFAEPD SSG +L +LA L D Sbjct: 67 SLASVGRWPWGRNKLADLVNKLFTEHKIAILGVDVVFAEPDDSSGLQQLKELAKSELSDQ 126 Query: 142 PQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPPAFSVADLGGR 201 P F +LQ L P++DYD A L G+P+V+GY +N+ + G LP P F L GR Sbjct: 127 PVFLAKLQDLSPRLDYDGVFASVLAGKPIVLGYFFTNDPQGRSSGVLPSPVFLEEALAGR 186 Query: 202 ALDVTHWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHFYESLALATAR 261 L+ W AYG+N+ L AAA G FN D DG++R+VPL+A ++ESL+LA R Sbjct: 187 TLEAPEWTAYGSNISSLAAAAPMAGHFNSFTDPDGVVRSVPLVAHYKNAYFESLSLAMFR 246 Query: 262 VALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHLTTLVSYRGKG 321 + RI P + ++ L + + + + + + L IPV+R L+ +RG G Sbjct: 247 AIVGMPRITPSY-SKETFLPKA----FQGVDKMLLVQGDKTLGIPVDRRGGALIPFRGAG 301 Query: 322 GPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPVYPGVEIHANL 381 GG+F+YV A DV++ +L +I+L+GTT GL D+R TPV YPGVE HAN+ Sbjct: 302 NAQGGSFQYVSAADVLQNRIATGKLKDKIVLLGTTALGLFDMRVTPVGEAYPGVETHANM 361 Query: 382 IASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLATAAGLGGLNFW 441 +++++DG +PD+A+GY+L+ ++ G++L + LP+L L +++L+ L +N W Sbjct: 362 LSALLDGHVLVKPDYAMGYELVVLVISGLVLAIGLPLLSALRAVILSTGVLVCLLLMNIW 421 Query: 442 LYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAPELVAEMAANP 501 Y G+VLPLA AL + + F N+ +GY E R+++ + NLFG YV PELV EM +P Sbjct: 422 PYLGYGLVLPLAGALAMTVTAFALNMSYGYFVESRSKRDLANLFGTYVPPELVDEMVQDP 481 Query: 502 ASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIRGNRGTLDKYI 561 SY+M+ RE+TVMF D+RGFT +SE+++P +L++ + + ++ IR NRGT+DKY+ Sbjct: 482 DSYSMKAMNREMTVMFCDMRGFTNMSEAMEPLQLQQMLTGVFSRLTSVIRANRGTIDKYM 541 Query: 562 GDAVMAFWGAPLALPDHAARAXNSS 586 GD VMAFWGAP+ DHA A +S Sbjct: 542 GDCVMAFWGAPVESEDHAQLAVKAS 566 >ref|YP_004158173.1| adenylate/guanylate cyclase with chase sensor [Variovorax paradoxus EPS] gb|ADU40062.1| adenylate/guanylate cyclase with Chase sensor [Variovorax paradoxus EPS] Length = 750 Score = 445 bits (1145), Expect = e-122, Method: Compositional matrix adjust. Identities = 245/583 (42%), Positives = 347/583 (59%), Gaps = 32/583 (5%) Query: 18 TAFATYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQP-DLDPRIVIV 76 A +W R ++ L+ LA A L +ER+D YD+R+R P LD R+VIV Sbjct: 2 NALQRHWPRIVITLLPVLLALAHATGLWQLSTLERLDHLIYDMRLRATMPRTLDTRVVIV 61 Query: 77 DIDEKSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADG 136 D+D+ S+A G+WPW+RD +A+L ++ Q +GFDV+F EPD SSG RL Q+A G Sbjct: 62 DVDDASLARQGQWPWARDTMARLTTELLVRQQVAVLGFDVMFLEPDRSSGLQRLRQIASG 121 Query: 137 PLKDVPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPP-PAFSV 195 PL+++ A +++ L P +D+D A AL + V +GY + AKGQLP P Sbjct: 122 PLRNMTGLAAEIERLAPTLDHDITFAAALHNRRVALGYYFTRTPVPSAKGQLPSAPLLPP 181 Query: 196 ADLGGRALDVTHWRAYGANLPQLQAAARAGGFFNPVPDD--DGLIRAVPLMAQV-GEH-- 250 A T W +GA+LP L AA GF N + + DG+IR+VPL+A+ GEH Sbjct: 182 DTFPKGACYATAWSGFGASLPMLAEAAPVAGFLNTLIGETGDGVIRSVPLIARYEGEHAN 241 Query: 251 --FYESLALATARVALDGRRIKPIF-----LQRQDVLFEGQLRDYGALAGIAVETRPQPL 303 +YESLALA R+A ++P+ +QR D L G+LR Sbjct: 242 PGYYESLALAVYRLANGSPPVRPLLAPGGAMQRLDSLALGRLR----------------- 284 Query: 304 FIPVERHLTTLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDL 363 IPV+++ + V +RG GG +GG+FRYV A DV+ G +L +I+L+G T PGL DL Sbjct: 285 -IPVDQNASMQVPFRGPGGADGGSFRYVAAADVVEGRLAPGELKDKIVLMGATAPGLQDL 343 Query: 364 RATPVNPVYPGVEIHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLW 423 RATPV +PGVE+HAN+++ ++D A PD+A GY++L VL G +L L +L Sbjct: 344 RATPVGAAFPGVEVHANIVSGLLDQRLLAVPDYAPGYEVLTVLVAGFVLAFGLSLLSAPR 403 Query: 424 SIVLTLATAAGLGGLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVN 483 +++L TAA L GLN WLY +VLPLA+AL++ A F N+ WGY E R R+ +V Sbjct: 404 AVLLGAGTAAVLIGLNTWLYIGHSLVLPLASALVMTALAFALNMSWGYFVESRARRGLVR 463 Query: 484 LFGEYVAPELVAEMAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYL 543 LFG YV P+LV EM P SY+M E +++TV+F D+R FT +SE + P EL+ ++N Sbjct: 464 LFGTYVPPQLVDEMLVRPGSYSMRAESKQMTVLFCDMRDFTRLSEQMAPAELQAFLNTVF 523 Query: 544 TAMSEDIRGNRGTLDKYIGDAVMAFWGAPLALPDHAARAXNSS 586 + ++ I +RGT+DKY+GD VMAFWGAP+ PDHAA A ++ Sbjct: 524 SRLTNVISAHRGTVDKYMGDCVMAFWGAPIDTPDHAALAVRAA 566 >ref|ZP_08505392.1| Adenylate/guanylate cyclase with Chase sensor [Methyloversatilis universalis FAM5] gb|EGK71068.1| Adenylate/guanylate cyclase with Chase sensor [Methyloversatilis universalis FAM5] Length = 745 Score = 437 bits (1124), Expect = e-120, Method: Compositional matrix adjust. Identities = 247/562 (43%), Positives = 344/562 (61%), Gaps = 7/562 (1%) Query: 22 TYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQPDL-DPRIVIVDIDE 80 ++ R+ L LVL + L ++ +D YD ++ + P + D R+VI+DIDE Sbjct: 3 SHLLRYGLGLVLMAVLLGHAARLYQLPVLGNLDHIAYDTKLHLTMPRVRDERVVILDIDE 62 Query: 81 KSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKD 140 +S+AE+GRWPW R+ +A L+ + Y +G DVVFAEPDTSSG L LA GPL Sbjct: 63 RSLAEIGRWPWGRERLAGLMDTLFDHYGVMLLGVDVVFAEPDTSSGLATLDALAKGPLAG 122 Query: 141 VPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPPAFSVADLGG 200 F L L+P++DYD+ A +L +PV++GY S+ + + G LP P G Sbjct: 123 DAGFRAALDELRPKLDYDSLFATSLDKRPVLLGYYFSDRSDGQSSGALPDPVLPAGTFRG 182 Query: 201 RALDVTHWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHFYESLALATA 260 R + + ++GANLP+ Q+AA G FNP+PD DGL R VP++ + +YESL+LA Sbjct: 183 RNIAFASFNSFGANLPRFQSAAMGAGHFNPMPDFDGLNRRVPMLVEHKGAYYESLSLAIV 242 Query: 261 RVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHLTTLVSYRGK 320 R L R+ P + + F RDYG L + + + L IPV+ ++ L+ YRG Sbjct: 243 RTLLGSPRLVPGYAEGG--FFGVSARDYGGLEWLELPSARGTLRIPVDENVAALIPYRGP 300 Query: 321 GGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPVYPGVEIHAN 380 G +F Y DV+ G P L G++ L+GTT PGL DLRATPV YPGVEIHAN Sbjct: 301 QG----SFAYYSLADVLAGKTPVEALKGKVALLGTTAPGLLDLRATPVGSTYPGVEIHAN 356 Query: 381 LIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLATAAGLGGLNF 440 LIA ++DG K RP + G+D++ +L VG LL LLP L PL + +L+ T L G+NF Sbjct: 357 LIAGMLDGRIKHRPQYVTGFDVVVLLLVGGLLLWLLPRLSPLNATLLSGGTLVLLVGMNF 416 Query: 441 WLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAPELVAEMAAN 500 + A VLP+A LLLV L+ N+ +GY FE R+++ +FG+YV PELV EM+ N Sbjct: 417 AFWQYADFVLPVAAGLLLVVGLYALNMSYGYFFESRSKRQFARMFGQYVPPELVEEMSRN 476 Query: 501 PASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIRGNRGTLDKY 560 P +Y+M+G ELT++FSD+RGFT+ISE L+P EL + +N YL AM+ I+ RGTLDKY Sbjct: 477 PENYSMDGRNAELTILFSDIRGFTSISEGLEPKELTQLMNEYLGAMTFVIQDQRGTLDKY 536 Query: 561 IGDAVMAFWGAPLALPDHAARA 582 IGDA+MAFWGAP++ DHA+ Sbjct: 537 IGDAIMAFWGAPVSDTDHASHG 558 >ref|YP_002947055.1| adenylate/guanylate cyclase with Chase sensor [Variovorax paradoxus S110] gb|ACS21789.1| adenylate/guanylate cyclase with Chase sensor [Variovorax paradoxus S110] Length = 758 Score = 436 bits (1122), Expect = e-120, Method: Compositional matrix adjust. Identities = 252/582 (43%), Positives = 347/582 (59%), Gaps = 27/582 (4%) Query: 18 TAFATYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQP-DLDPRIVIV 76 TA +W R + L+ LA A L ++R+D YD R+R P LDPRIVIV Sbjct: 2 TALRRHWPRIAITLLPVLLALAHATGLWRLDAIDRLDHLIYDTRLRATMPGTLDPRIVIV 61 Query: 77 DIDEKSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADG 136 D+D+ S+ G+WPWSRD +A+L R++T QA ++GFDV+F EPD SSG +L Q+A G Sbjct: 62 DVDDASLTRQGQWPWSRDKLARLTRELTGRQQAAALGFDVMFVEPDRSSGLDKLRQIARG 121 Query: 137 PLKDVPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAKGQLPPPAFSVA 196 PL+++P A ++ L P +D DA A A++GQ V +GY + AKG+LPP A Sbjct: 122 PLREMPGLAAEIDRLAPTLDNDAIFAAAMQGQRVALGYYFTRTEKPGAKGRLPPAPVLQA 181 Query: 197 DL--GGRALDVTHWRAYGANLPQLQAAARAGGFFNP--VPDDDGLIRAVPLMAQV-GEH- 250 + GR T W +GA+LP L AA A GF N + + DG+IRAVPL+A+ G+ Sbjct: 182 EAFPPGRGY-ATAWNGFGASLPVLADAAPAAGFLNTLVMSNGDGVIRAVPLIARYEGDRA 240 Query: 251 ---FYESLALATARVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRP---QPLF 304 +YESL LA R+A ++P F G G A + L Sbjct: 241 RPGYYESLGLAVYRLASGSPPVRPAFAP-------------GGSGGAAPPLQSLLVGGLR 287 Query: 305 IPVERHLTTLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLR 364 IPV + V +RG GG +GG+FRYV A DV+ G +L RI+LVG T PGL DLR Sbjct: 288 IPVNEAASMQVPFRGPGGAHGGSFRYVSAGDVLEGRLAPGELKDRIVLVGATAPGLQDLR 347 Query: 365 ATPVNPVYPGVEIHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWS 424 ATPV +PGVE+HAN++++++D A PD+A GY++L VLA G++L L L +L + Sbjct: 348 ATPVGAAFPGVEVHANIVSAMLDHRLLAVPDYAPGYEVLSVLAAGLVLALGLSLLPAPRA 407 Query: 425 IVLTLATAAGLGGLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNL 484 +VL +AT A L G+N WLY +VLPLA+AL + F N+GWGY E R R+ +V L Sbjct: 408 VVLAIATLAALVGVNAWLYQRHSLVLPLASALTMAVLAFAFNMGWGYFIESRARRGLVRL 467 Query: 485 FGEYVAPELVAEMAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLT 544 FG YV P+LV EM P Y+M E + +TVMF D+R FT +SE + P EL+ ++N Sbjct: 468 FGTYVPPQLVKEMLVTPGRYSMRAESKHMTVMFCDMRNFTRLSEQMAPAELQAFLNNVFN 527 Query: 545 AMSEDIRGNRGTLDKYIGDAVMAFWGAPLALPDHAARAXNSS 586 ++ I +RGT+DKY+GD VMAFWGAP+ P+HA A ++ Sbjct: 528 RLTSVISTHRGTVDKYMGDCVMAFWGAPIDTPEHATLAVRAA 569 >ref|YP_003523160.1| adenylate/guanylate cyclase with Chase sensor [Sideroxydans lithotrophicus ES-1] gb|ADE10773.1| adenylate/guanylate cyclase with Chase sensor [Sideroxydans lithotrophicus ES-1] Length = 725 Score = 431 bits (1109), Expect = e-118, Method: Compositional matrix adjust. Identities = 233/538 (43%), Positives = 331/538 (61%), Gaps = 15/538 (2%) Query: 49 LVERMDLFFYDLRMRVAQPD-LDPRIVIVDIDEKSIAELGRWPWSRDVIAQLVRQMTQTY 107 V+ +D YD R+ + P D RIVI+DIDEKS+ E GRWPW R+ +A ++ ++ Y Sbjct: 12 FVQFIDAKLYDYRLLLTLPKKADDRIVILDIDEKSLKEEGRWPWGRNKMAVMMDELFDHY 71 Query: 108 QAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKDVPQFARQLQALKPQMDYDARLAEALRG 167 VGFDVVFAE D SSG L L K V QF L +KP ++YD AE ++ Sbjct: 72 GVAVVGFDVVFAEKDNSSGLNVLQDLGRSQFKGVAQFQSVLAQIKPHLEYDKLFAEKIKN 131 Query: 168 QPVVMGYNLSNEAGAIAK---GQLPPPAFSVADLGGRALDVTHWRAYGANLPQLQAAARA 224 + VV+GY SN K G LP P F GR + W +YGANLP+LQ++A Sbjct: 132 RNVVLGYYFSNSERGHDKSRSGVLPEPVFPAGTFKGRPISFMQWDSYGANLPELQSSAAL 191 Query: 225 GGFFNPVPDDDGLIRAVPLMAQVGEHFYESLALATARVALDGRRIKPIFLQRQDVLFEGQ 284 G FNPV D DG++R +P++ + +YESL+LA R AL ++ P + +D Sbjct: 192 AGHFNPVVDFDGVVRRIPMIVEYDGAYYESLSLAVVRAALGMPKLLPGYAAGKD------ 245 Query: 285 LRDYGALAGIAVETRPQPLFIPVERHLTTLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHA 344 ++YG L + +++ L IPV+ ++ LV YRG G FRY+ A DV+ P A Sbjct: 246 -KNYGGLEWLTLQSAQGDLRIPVDAEVSALVPYRGARG----TFRYISATDVLHERIPKA 300 Query: 345 QLDGRIMLVGTTVPGLNDLRATPVNPVYPGVEIHANLIASIIDGDFKARPDFAVGYDLLQ 404 L RI+LVGT+ PGL D+R+TPV VYPGVE+HAN+I+ ++D D K P + +G ++L Sbjct: 301 DLQNRIVLVGTSAPGLMDMRSTPVGEVYPGVEVHANMISGMLDQDLKQNPPYVLGANVLM 360 Query: 405 VLAVGVLLGLLLPMLGPLWSIVLTLATAAGLGGLNFWLYDSAGMVLPLATALLLVASLFI 464 +L VGV+L LLLP+L P++ +L+ A +N +L++ + LPLA L++V +LF Sbjct: 361 LLLVGVILALLLPLLSPVYGTLLSAGLLAFEVLVNGYLWEYGNIALPLAGGLIMVFALFA 420 Query: 465 CNLGWGYLFEYRNRKAIVNLFGEYVAPELVAEMAANPASYNMEGEIRELTVMFSDVRGFT 524 N+ +GY R ++ I +LFG+YV E+V EM+ NP +MEGE RE+T++F+DVRGFT Sbjct: 421 LNMTYGYFTTERTKRQITSLFGQYVPSEVVDEMSKNPEQVSMEGESREMTILFTDVRGFT 480 Query: 525 TISESLQPNELREYINVYLTAMSEDIRGNRGTLDKYIGDAVMAFWGAPLALPDHAARA 582 TISE L+P EL + +N +LT +S + +RGT+DKY+GD +MAFWGAPL HA A Sbjct: 481 TISEGLEPRELSQLMNEFLTPLSRVVYSHRGTIDKYMGDCIMAFWGAPLPDVRHAYHA 538 >ref|YP_546237.1| adenylate/guanylate cyclase [Methylobacillus flagellatus KT] gb|ABE50396.1| adenylate/guanylate cyclase [Methylobacillus flagellatus KT] Length = 741 Score = 410 bits (1054), Expect = e-112, Method: Compositional matrix adjust. Identities = 250/574 (43%), Positives = 341/574 (59%), Gaps = 20/574 (3%) Query: 15 RLRTAFATYWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQP-DLDPRI 73 R+ +F+ + R LL ++ T + A V+ +E M+ F YD R+R+ P D D RI Sbjct: 2 RIPRSFSHHHIRLLLGVLATAILLAHVVGAFRLDFMEAMERFAYDTRIRLLAPEDHDDRI 61 Query: 74 VIVDIDEKSIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQL 133 VIVDIDE S+ + G WPWSR +AQL+ + YQ + V FDVVFAE D SSG L + Sbjct: 62 VIVDIDEASLQQEGHWPWSRKRLAQLLDLLFDHYQVRLVAFDVVFAEKDHSSGLAALQAM 121 Query: 134 ADGPLKDVPQFARQLQALKPQMDYDARLAEALRGQPVVMGYNLSNEAGAIAK-GQLPPPA 192 P++ + A+ P +D+D + A+++RG+ VV+GY + G LPPP Sbjct: 122 RQAQFTQRPEWVPLIDAILPALDHDRQFADSMRGRNVVLGYYFRHGTDMGRNIGMLPPPV 181 Query: 193 FSVADLGGRALDVTHWRAYGANLPQLQAAARAGGFFNPVPDDDGLIRAVPLMAQVGEHFY 252 L GR + YGANLP LQ A A G FNP PD+DG+ R VPL+ Y Sbjct: 182 MQADMLAGRHVAYLQASGYGANLPILQQQAAAAGHFNPDPDEDGITRRVPLLVAYQGGMY 241 Query: 253 ESLALATARVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAVETRPQPLFIPVERHLT 312 E+L+LA R L ++ P F Y + + + R IPV+ +L Sbjct: 242 EALSLAVVRRVLGNVQVAPGFTDSMQ---------YAGMEWLELGQRK----IPVDANLN 288 Query: 313 TLVSYRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPVY 372 TL+ YRGK G +F YV A DV+ G QL RI+L+GTT PGL DLRATPV VY Sbjct: 289 TLIPYRGKQG----SFSYVSATDVLHGRVSPQQLQNRIVLIGTTAPGLMDLRATPVQSVY 344 Query: 373 PGVEIHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLATA 432 PGVEIHA+LI+ ++DG+ +P + G + L ++ +GV L +L+P + P+ + VL LAT Sbjct: 345 PGVEIHASLISGMLDGNILQQPGYTRGAEFLLLMLLGVGLSILIPRMSPVPATVLALATW 404 Query: 433 AGLGGLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAPE 492 A L G N + AG+VLPLA+ALLLV L++ N+ +GY E R+R+ + LFG+YV P Sbjct: 405 ALLTGFNLMAW-QAGIVLPLASALLLVLLLYVLNMSYGYFIESRSRRHLAQLFGQYVPPA 463 Query: 493 LVAEMAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIRG 552 LVAEM P +EGE RE+TV+F D+R FT ISE+L P L + +N YLTAM+ I Sbjct: 464 LVAEMVERPHQLGLEGESREMTVLFCDIRDFTRISEALDPQALAKLMNEYLTAMTRVIHQ 523 Query: 553 NRGTLDKYIGDAVMAFWGAPLALPDHAARAXNSS 586 +RGT+DKY+GDA+MAFWGAPL HAA A N++ Sbjct: 524 HRGTIDKYMGDAIMAFWGAPLHDDRHAANAVNAA 557 >ref|ZP_05062227.1| adenylate/guanylate cyclase [gamma proteobacterium HTCC5015] gb|EDY85899.1| adenylate/guanylate cyclase [gamma proteobacterium HTCC5015] Length = 734 Score = 409 bits (1050), Expect = e-111, Method: Compositional matrix adjust. Identities = 241/566 (42%), Positives = 350/566 (61%), Gaps = 31/566 (5%) Query: 23 YWARWLLALVLTGLATAQVMALLPNRLVERMDLFFYDLRMRVAQPD-LDPRIVIVDIDEK 81 + R LL+L+L L AQ + +++ ++ YDLR+ +PD +D RIVI+D+DEK Sbjct: 5 FSVRILLSLILVALFIAQAGPWMNIQIISSLENIAYDLRLNATRPDTVDDRIVILDLDEK 64 Query: 82 SIAELGRWPWSRDVIAQLVRQMTQTYQAQSVGFDVVFAEPDTSSGYGRLAQLADGPLKDV 141 S++E+GRWPWSR +A+L+ Q+ + Y + +GFD+VFAE D SSG L LA+G LKDV Sbjct: 65 SLSEVGRWPWSRHHMAELLDQLFEHYNIRVIGFDMVFAEADESSGLNVLQTLANGALKDV 124 Query: 142 PQFARQLQALKPQMDYDARLAEALRGQPVVMGY--NLSNEAGAIAKGQLPPPAFSVADLG 199 P+F ++ Q L+ + YD R A++L+ +PV+MGY NL++E K + PP+ Sbjct: 125 PEFTQEFQTLRQSLKYDQRFADSLKDRPVIMGYVFNLNSED----KYNILPPSLGEV--- 177 Query: 200 GRALDVTHWRAYGANLPQLQAAARAGGFF-NPVPDDDGLIRAVPLMAQVGEHFYESLALA 258 G L Y NL LQ A GGFF NP D+DG+ R VPL+ YESLA+A Sbjct: 178 GDGLHFIQPEGYTGNLEILQKNAAGGGFFDNPRVDEDGIFRRVPLLQSHDGELYESLAMA 237 Query: 259 TARVALDGRRIKPIFLQRQDVLFEGQLRDYGALAGIAV--ETRPQPLFIPVERHLTTLVS 316 T R+AL + R + +G +Y A+ I + E R I V+++ + LV Sbjct: 238 TTRMALGFPEM------RIETYSDGG--NYQAIESITLGDEYR-----INVDKNTSVLVP 284 Query: 317 YRGKGGPNGGAFRYVPAVDVIRGTYPHAQLDGRIMLVGTTVPGLNDLRATPVNPVYPGVE 376 YRG+ G +F YV AVD ++ + L G+I+L+GT+ PGL DLR+TPV YPGVE Sbjct: 285 YRGRQG----SFPYVSAVDALKQRVDQSALQGKIVLLGTSAPGLLDLRSTPVEKNYPGVE 340 Query: 377 IHANLIASIIDGDFKARPDFAVGYDLLQVLAVGVLLGLLLPMLGPLWSIVLTLATAAGLG 436 +HAN+I+ I+D K +P + +G ++L +L +G+ + + +L PLWS TL Sbjct: 341 VHANVISGILDNRIKHQPSYTLGVEVLVLLVLGIAMIAITALLSPLWSTAFTLGLMLVTI 400 Query: 437 GLNFWLYDSAGMVLPLATALLLVASLFICNLGWGYLFEYRNRKAIVNLFGEYVAPELVAE 496 N ++ AG+V+P+A LLL+ LFI ++ +G+ E R ++A+ LFG+Y+ PELV E Sbjct: 401 AFNMLAWE-AGLVVPIANTLLLLLGLFILHMSYGFFIESRGKRALAKLFGQYIPPELVDE 459 Query: 497 MAANPASYNMEGEIRELTVMFSDVRGFTTISESLQPNELREYINVYLTAMSEDIRGNRGT 556 M+A+P ++G+ RE+TV+FSDVRGFTTISE L P EL + +N +LT M+ I +RGT Sbjct: 460 MSADPTEIVLDGQSREMTVLFSDVRGFTTISEGLDPKELTQLMNSFLTPMTRIIHHHRGT 519 Query: 557 LDKYIGDAVMAFWGAPLALPDHAARA 582 +DKY+GDAVMAFWGAPL HA A Sbjct: 520 IDKYMGDAVMAFWGAPLDDAYHAKNA 545