BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0173.p (241 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773743.1| cAMP phosphodiesterase-like protein [Herbasp... 486 e-136 ref|YP_003523161.1| beta-lactamase domain protein [Sideroxydans ... 293 2e-77 ref|ZP_08505393.1| Beta-lactamase domain protein [Methyloversati... 285 5e-75 gb|EGW60104.1| beta-lactamase domain protein [Dechlorosoma suill... 282 3e-74 ref|YP_003165936.1| beta-lactamase domain-containing protein [Ca... 281 5e-74 ref|YP_286557.1| Beta-lactamase-like [Dechloromonas aromatica RC... 279 3e-73 ref|YP_003048045.1| beta-lactamase domain-containing protein [Me... 274 1e-71 ref|YP_004295182.1| cyclic-AMP phosphodiesterase [Nitrosomonas s... 269 3e-70 ref|YP_003050376.1| beta-lactamase domain-containing protein [Me... 268 5e-70 ref|YP_003848317.1| cyclic-AMP phosphodiesterase class-II [Galli... 264 1e-68 >ref|YP_003773743.1| cAMP phosphodiesterase-like protein [Herbaspirillum seropedicae SmR1] gb|ADJ61835.1| cAMP phosphodiesterases protein [Herbaspirillum seropedicae SmR1] Length = 257 Score = 486 bits (1252), Expect = e-136, Method: Compositional matrix adjust. Identities = 240/241 (99%), Positives = 240/241 (99%) Query: 1 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT 60 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT Sbjct: 17 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT 76 Query: 61 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP 120 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP Sbjct: 77 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP 136 Query: 121 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELA 180 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRI QLRYLIIEAAFANRERELA Sbjct: 137 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIVQLRYLIIEAAFANRERELA 196 Query: 181 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILE 240 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILE Sbjct: 197 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILE 256 Query: 241 L 241 L Sbjct: 257 L 257 >ref|YP_003523161.1| beta-lactamase domain protein [Sideroxydans lithotrophicus ES-1] gb|ADE10774.1| beta-lactamase domain protein [Sideroxydans lithotrophicus ES-1] Length = 254 Score = 293 bits (749), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 134/241 (55%), Positives = 178/241 (73%), Gaps = 2/241 (0%) Query: 1 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT 60 +RTTS+L+D D+LIDAGTG+GDL+L + IDHVF+TH+HLDHIACLPL++DSVG MR Sbjct: 16 LRTTSMLLDHDVLIDAGTGIGDLSLAEMCVIDHVFVTHSHLDHIACLPLLVDSVGFMRDQ 75 Query: 61 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP 120 P+ +HAT TL+I+R+H+FNW IWPDF+ IPS QP LR+ I G+TV +G R IT LP Sbjct: 76 PLVIHATDETLDILRQHVFNWEIWPDFTEIPSLHQPILRYERIVLGETVDMGGRKITPLP 135 Query: 121 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELA 180 A H VPAVGYQ+ + ++ SL F+GDTT C LW+ +NRI L YLI+E AF+N E+ELA Sbjct: 136 ANHVVPAVGYQIDSGKT--SLVFTGDTTTCDALWEEVNRIRNLEYLIVETAFSNAEKELA 193 Query: 181 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILE 240 ++SKHLCP+LL EEL L+ P++ +TH KP +++ EI+ P+ML+ G I E Sbjct: 194 VVSKHLCPSLLAEELCKLKLNPKIYITHLKPGEIELTMQEISDCVGNFVPKMLQNGQIFE 253 Query: 241 L 241 Sbjct: 254 F 254 >ref|ZP_08505393.1| Beta-lactamase domain protein [Methyloversatilis universalis FAM5] gb|EGK71069.1| Beta-lactamase domain protein [Methyloversatilis universalis FAM5] Length = 255 Score = 285 bits (729), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 133/241 (55%), Positives = 176/241 (73%), Gaps = 2/241 (0%) Query: 1 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT 60 +RTTSLL+DDDILIDAGTGVGDL++ L IDHVF+TH+HLDHIACLPLMID+VG++R Sbjct: 17 LRTTSLLVDDDILIDAGTGVGDLSIAELARIDHVFVTHSHLDHIACLPLMIDTVGELRTR 76 Query: 61 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP 120 P+T+ +A TLE++R+HIFNW IWPDF+ IPS E+PF+ F + G + +G R+I LP Sbjct: 77 PLTVWTSAPTLEVLRRHIFNWSIWPDFTEIPSVERPFMCFRELRVGDEIDMGNRAIRVLP 136 Query: 121 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELA 180 A HTVPAVGY V+ G +LAFSGDTTVC W A+N + LR+LIIE AF +R+R+LA Sbjct: 137 AQHTVPAVGYAVRG--PGGTLAFSGDTTVCDEFWDAVNALPDLRHLIIETAFPDRDRQLA 194 Query: 181 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILE 240 ++S+HLCP +L EL+ L+ ++ +TH KPSQ+ EIA + PRML + + Sbjct: 195 VMSRHLCPDMLAGELEKLRHEADIYITHLKPSQMDITMREIAETLGSRSPRMLRNNHVFD 254 Query: 241 L 241 Sbjct: 255 F 255 >gb|EGW60104.1| beta-lactamase domain protein [Dechlorosoma suillum PS] Length = 257 Score = 282 bits (722), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 141/243 (58%), Positives = 176/243 (72%), Gaps = 4/243 (1%) Query: 1 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMR-P 59 +RTTS+L+D D+L+DAGTGV DL+L L AIDH+F+TH+HLDHIA LPL+ID+V DMR Sbjct: 17 LRTTSMLVDHDVLVDAGTGVADLSLAELGAIDHIFLTHSHLDHIASLPLLIDTVMDMRIG 76 Query: 60 TPITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALG-QRSITA 118 P+T+HA+ ATL I+R+H+FNW +WPDFS IPS E P L+F +E GQ V LG RSITA Sbjct: 77 RPVTVHASEATLAILRQHVFNWLVWPDFSEIPSREAPCLQFQAMELGQRVDLGCGRSITA 136 Query: 119 LPAAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERE 178 LPA HTVPAVGY + + SLAFSGDTT W +N +A LRYLIIE AF+N+ER Sbjct: 137 LPAEHTVPAVGYLL--DSGSNSLAFSGDTTSNDSFWPRVNEVANLRYLIIETAFSNKERA 194 Query: 179 LALLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTI 238 LA+ SKHLCP+LL EEL L EV +TH KP Q+++ EI G +PRML+ + Sbjct: 195 LAIASKHLCPSLLAEELAKLARPAEVFITHLKPGQIEQTMQEIEEGVAGFKPRMLQNNQV 254 Query: 239 LEL 241 EL Sbjct: 255 FEL 257 >ref|YP_003165936.1| beta-lactamase domain-containing protein [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gb|ACV34007.1| beta-lactamase domain protein [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length = 255 Score = 281 bits (720), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 137/240 (57%), Positives = 172/240 (71%), Gaps = 2/240 (0%) Query: 2 RTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPTP 61 RTTS+L+DDD+LIDAGTGV DL+L L IDHVF+TH+HLDHIA LPL++DSV D+R P Sbjct: 18 RTTSMLVDDDLLIDAGTGVADLSLAELAVIDHVFLTHSHLDHIASLPLLVDSVSDLRDKP 77 Query: 62 ITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALPA 121 +T++ATA TL II KHIFNW IWPDF VIPS E+ +R+ +I GQ+V LG R+ITALPA Sbjct: 78 LTVYATAETLAIIGKHIFNWVIWPDFRVIPSPEEAVMRYRSIALGQSVRLGGRTITALPA 137 Query: 122 AHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELAL 181 HTVPAVGYQ+ + SL F+GDTT+ W +N IA LR+L+IE AF N ER LA Sbjct: 138 EHTVPAVGYQL--DSGSGSLVFTGDTTINDAFWPVVNSIANLRFLLIETAFPNHERRLAE 195 Query: 182 LSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILEL 241 +SKHLCP++L EL L EV V+H KP Q + AEI + + +PRML+ + E Sbjct: 196 VSKHLCPSMLATELTKLTIAAEVYVSHLKPGQSELTMAEIESCAGSFKPRMLQHNQVFEF 255 >ref|YP_286557.1| Beta-lactamase-like [Dechloromonas aromatica RCB] gb|AAZ48087.1| Beta-lactamase-like protein [Dechloromonas aromatica RCB] Length = 255 Score = 279 bits (713), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 135/240 (56%), Positives = 168/240 (70%), Gaps = 2/240 (0%) Query: 2 RTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPTP 61 RTTS L+D DILIDAGTGVG+L++ + AIDHVF+THAHLDHI LPLMIDSVGD R P Sbjct: 18 RTTSFLVDHDILIDAGTGVGELSIAEMAAIDHVFLTHAHLDHIVSLPLMIDSVGDRRRKP 77 Query: 62 ITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALPA 121 + ++ T A L+ +R+HIFNW IWPDFSV+P A+QPF+R+ TIE G TV LG R I+ALP Sbjct: 78 LMVYGTQAVLDTLRQHIFNWSIWPDFSVLPRADQPFMRYQTIETGATVTLGDRGISALPV 137 Query: 122 AHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELAL 181 HTVPAVGY + + ASL FSGDT C WQ LNR+ LR+LIIE AF+N+E+ LA Sbjct: 138 DHTVPAVGYCL--DSGAASLVFSGDTGPCDAFWQGLNRLDNLRHLIIECAFSNQEQGLAE 195 Query: 182 LSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILEL 241 SKH CP LL EL+ L+ E+ +TH KP Q++ AEI + ML+ + E Sbjct: 196 ASKHYCPTLLAAELRKLERSCEIHITHLKPGQIETTMAEIGSCLGDFDLSMLQNDQVFEF 255 >ref|YP_003048045.1| beta-lactamase domain-containing protein [Methylotenera mobilis JLW8] gb|ACT47518.1| beta-lactamase domain protein [Methylotenera mobilis JLW8] Length = 260 Score = 274 bits (700), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 133/245 (54%), Positives = 172/245 (70%), Gaps = 7/245 (2%) Query: 2 RTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPTP 61 RTTSLL+D DILIDAG+GVGDL+++ L I H+F+TH+HLDHIA +PL++D+V +R P Sbjct: 18 RTTSLLLDHDILIDAGSGVGDLSMDELLKISHIFVTHSHLDHIAFIPLLLDTVMGIRSEP 77 Query: 62 ITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALPA 121 IT++AT TL I++ HIFNW IWPDF+ IP+A PFLR+ I+ GQ V LG R+ITALP Sbjct: 78 ITLYATQETLAILQAHIFNWKIWPDFNAIPNATAPFLRYQEIKLGQPVVLGGRTITALPV 137 Query: 122 AHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELAL 181 H VPAVGY +K + SL ++GDTT+C LW A+N I L+YLI+E AF+N E ELA+ Sbjct: 138 HHVVPAVGYHIKG--AAHSLVYTGDTTICDALWHAVNNINHLKYLIVETAFSNSELELAV 195 Query: 182 LSKHLCPALLLEEL-----QHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAG 236 LSKHLCP++LL+EL HL EV +TH KP + I EIAAG + L Sbjct: 196 LSKHLCPSMLLQELAKLNAAHLTGALEVYITHLKPGEDAHIMREIAAGNAGLSIKALNRD 255 Query: 237 TILEL 241 + EL Sbjct: 256 QVFEL 260 >ref|YP_004295182.1| cyclic-AMP phosphodiesterase [Nitrosomonas sp. AL212] gb|ADZ27020.1| cyclic-AMP phosphodiesterase [Nitrosomonas sp. AL212] Length = 254 Score = 269 bits (687), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 122/239 (51%), Positives = 171/239 (71%), Gaps = 2/239 (0%) Query: 3 TTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPTPI 62 TT++L+DDD+LIDAGTGVG+LT+E + IDHV +THAHLDH+A +P ++D+VG MR PI Sbjct: 18 TTAMLLDDDVLIDAGTGVGNLTIEEMVRIDHVLVTHAHLDHVAFIPFLVDTVGSMRAKPI 77 Query: 63 TMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALPAA 122 +HA ATL+I++KH+FNW++WPDF+ IP A P++R+ + QT+ L QR IT LPA Sbjct: 78 IIHAIPATLDILQKHLFNWYLWPDFTKIPVATMPYMRYEALALNQTLCLNQRKITPLPAH 137 Query: 123 HTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELALL 182 HT+PAVGYQ+ + ASL F+GDTT LW A+N+I L+YLIIE+AF NR+R++A Sbjct: 138 HTIPAVGYQL--DSGQASLVFTGDTTTNDALWIAVNKIENLKYLIIESAFCNRKRDIAQR 195 Query: 183 SKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILEL 241 S+H CP+LL E+L+ L+ E+ +TH KP + + EI ++ PR LE + E Sbjct: 196 SRHYCPSLLAEDLKKLERTAEIFITHLKPGEAEITMQEINQCMESYHPRPLENNQLFEF 254 >ref|YP_003050376.1| beta-lactamase domain-containing protein [Methylovorus glucosetrophus SIP3-4] gb|ACT49849.1| beta-lactamase domain protein [Methylovorus glucosetrophus SIP3-4] Length = 254 Score = 268 bits (685), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 127/241 (52%), Positives = 164/241 (68%), Gaps = 2/241 (0%) Query: 1 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT 60 +RTTSLL+DDDILIDAGTGVGDL++E++ IDHVF+TH+HLDHIACLPLM+D+V +R Sbjct: 16 LRTTSLLVDDDILIDAGTGVGDLSIEQMAKIDHVFLTHSHLDHIACLPLMLDTVAGLREA 75 Query: 61 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP 120 P+T+H TL ++ HIFNW IWPDFS +PS P LR+A + G+ V+L RSIT LP Sbjct: 76 PVTIHGLPETLHALKTHIFNWIIWPDFSAVPSETSPLLRYAEVAQGKAVSLSGRSITPLP 135 Query: 121 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELA 180 A HTV AVGY + + S+ F+GDTT C LW+ +N+I L+YL+IE AF N E LA Sbjct: 136 ANHTVAAVGYWL--DSGAGSMVFTGDTTTCDALWEQVNQIENLKYLLIETAFGNDELALA 193 Query: 181 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAGGTAHRPRMLEAGTILE 240 + SKHLCP+LL +EL L+ V +TH KP + EI I R L+ + E Sbjct: 194 VTSKHLCPSLLFDELGKLKKSAHVYITHLKPGEGAEIMYHIEQSSQHAGLRGLQNMQVFE 253 Query: 241 L 241 L Sbjct: 254 L 254 >ref|YP_003848317.1| cyclic-AMP phosphodiesterase class-II [Gallionella capsiferriformans ES-2] gb|ADL56553.1| cyclic-AMP phosphodiesterase class-II [Gallionella capsiferriformans ES-2] Length = 254 Score = 264 bits (674), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 123/231 (53%), Positives = 166/231 (71%), Gaps = 4/231 (1%) Query: 1 MRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHIACLPLMIDSVGDMRPT 60 + TTS LID DILIDAGTGVG+L+L+ + IDH+FITHAH+DHI LPL++DSVG MR Sbjct: 16 LHTTSFLIDRDILIDAGTGVGELSLKEMSEIDHIFITHAHMDHICSLPLLMDSVGGMRAR 75 Query: 61 PITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIEPGQTVALGQRSITALP 120 P+T++A ATLE++++HIFNW IWPDFS IP+ P +R+ +E G+ + L R I+++P Sbjct: 76 PVTVYAAQATLEMLQRHIFNWEIWPDFSEIPNVAHPVMRYQAMELGEVITLQGRKISSVP 135 Query: 121 AAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIAQLRYLIIEAAFANRERELA 180 A H VPAVGY + + ASL FSGDT LW+ +N+IA LRYLIIE AF+N E++LA Sbjct: 136 AVHAVPAVGYHIDSGE--ASLVFSGDTCSNDALWRVVNQIANLRYLIIETAFSNAEKQLA 193 Query: 181 LLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEI--AAGGTAHR 229 +LS+HLCP+LL EEL + E+ ++H KP + + I EI GG+ R Sbjct: 194 VLSQHLCPSLLSEELAKFTGQAEIFISHLKPDEAELIMREIEMCLGGSGAR 244