BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0148.p (508 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773765.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- ... 1020 0.0 ref|YP_001354710.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-... 637 e-180 ref|YP_004754593.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-... 628 e-178 ref|YP_001101051.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-... 598 e-169 ref|ZP_08272723.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di... 558 e-157 ref|ZP_04579654.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di... 550 e-154 ref|ZP_04577501.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di... 545 e-153 ref|YP_727720.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia... 473 e-131 ref|YP_585274.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia... 473 e-131 ref|YP_004687007.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2... 466 e-129 >ref|YP_003773765.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase [Herbaspirillum seropedicae SmR1] gb|ADJ61857.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase [Herbaspirillum seropedicae SmR1] Length = 508 Score = 1020 bits (2638), Expect = 0.0, Method: Compositional matrix adjust. Identities = 506/508 (99%), Positives = 506/508 (99%) Query: 1 MPERALNLHDIQRTLRQAAPSAQLTSDSRRVAPGDVFFAYVGDADGRSYIADAVERGAAA 60 MPERALNLHDIQ LRQAAPSAQLTSDSRRVAPGDVFFAYVGDADGRSYIADAVERGAAA Sbjct: 1 MPERALNLHDIQAWLRQAAPSAQLTSDSRRVAPGDVFFAYVGDADGRSYIADAVERGAAA 60 Query: 61 VVYEAAGFTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYW 120 VVYEAAGFTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYW Sbjct: 61 VVYEAAGFTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYW 120 Query: 121 LGIALSRLAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGA 180 LGIALSRLAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGA Sbjct: 121 LGIALSRLAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGA 180 Query: 181 LAIEASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVV 240 LAIEASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVV Sbjct: 181 LAIEASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVV 240 Query: 241 NLDDDMGQRLLPLLAERKVPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPF 300 NLDDDMGQRLLPLLAERKVPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPF Sbjct: 241 NLDDDMGQRLLPLLAERKVPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPF 300 Query: 301 GSGQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLI 360 GSGQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLI Sbjct: 301 GSGQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLI 360 Query: 361 VIDYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLT 420 VIDYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLT Sbjct: 361 VIDYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLT 420 Query: 421 SDNPRSEDPQAIIDQIRAGMSRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQE 480 SDNPRSEDPQAIIDQIRAGMSRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQE Sbjct: 421 SDNPRSEDPQAIIDQIRAGMSRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQE 480 Query: 481 IAGKKLPFLDADHVALALAARSTMMGGA 508 IAGKKLPFLDADHVALALAARSTMMGGA Sbjct: 481 IAGKKLPFLDADHVALALAARSTMMGGA 508 >ref|YP_001354710.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Janthinobacterium sp. Marseille] sp|A6T2G3.1|MURE_JANMA RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=UDP-MurNAc-tripeptide synthetase; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase gb|ABR89221.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Janthinobacterium sp. Marseille] Length = 508 Score = 637 bits (1643), Expect = e-180, Method: Compositional matrix adjust. Identities = 320/495 (64%), Positives = 387/495 (78%), Gaps = 12/495 (2%) Query: 19 APSAQLTSDSRRVAPGDVFFAYVGD-ADGRSYIADAVERGAAAVVYEAAGFTWPAQIDVP 77 AP A+L SDSRR+A GDVF AY GD ADGRSYIA+A+ERGA AV+YEAAG TW A+ DV Sbjct: 20 APKAELASDSRRIAQGDVFVAYPGDEADGRSYIANAIERGAQAVIYEAAGCTWDAEWDVA 79 Query: 78 HLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIALSRLAGASTAGVI 137 HLA+ DLK HAGEIAA++Y PD+ M TVA+TGTNGKTSCA WLG ALSRL G TA VI Sbjct: 80 HLAIDDLKEHAGEIAAAYYAHPDRSMFTVAITGTNGKTSCAQWLGSALSRL-GQPTA-VI 137 Query: 138 GTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIEASSIGLAQGRMNG 197 GTLGVG F NG FDVTGYTTPDAVLLQRSL ++ ALAIEASSIGL QGR++G Sbjct: 138 GTLGVGIFTNGGHGSFDVTGYTTPDAVLLQRSLVNVSNLGATALAIEASSIGLHQGRLSG 197 Query: 198 MHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDDDMGQRLLPLLAER 257 MH D+AL TNFTRDHLD+HGDM YE+AK LF WPGL+HAV+NLDD MG RL+ L R Sbjct: 198 MHFDMALFTNFTRDHLDYHGDMAAYEEAKAMLFDWPGLQHAVINLDDAMGVRLVQRLQSR 257 Query: 258 K--VPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPFGSGQVKTQLVGRFNV 315 + V + GY ++D++ G+ LRA+ +RS+ +GTVF ++S G+ QVKTQLVG+FNV Sbjct: 258 QADVGITGYTLSDKK---IDGIAVLRATDIRSNQSGTVFQLESSAGNTQVKTQLVGQFNV 314 Query: 316 SNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLIVIDYAHTPDALDKTL 375 SNVLGI+G+LL +G+A V A AL+ PGRMQQ GG + PL+VIDYAHTPDAL+KTL Sbjct: 315 SNVLGIIGILLAKGIALQDAVNAVEALTAVPGRMQQLGGGEAPLVVIDYAHTPDALEKTL 374 Query: 376 STLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLTSDNPRSEDPQAIIDQ 435 +TLR +A RGG+LWCVFGCGGDRDPGKRPQMG+++ AD +V+T+DNPR+E+P II Sbjct: 375 ATLRSVANDRGGELWCVFGCGGDRDPGKRPQMGKVSMAADHIVVTTDNPRNEEPANIIGD 434 Query: 436 IRAGMS--RVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQEIAGKKLPFLDADH 493 I AG++ + P ++ DRA AILWA RHA + DV+LLAGKGHE+YQE+ G+KLPFLDADH Sbjct: 435 IVAGITAPKNAPQIIEDRASAILWAGRHAARQDVILLAGKGHEAYQEVKGRKLPFLDADH 494 Query: 494 VALALAARSTMMGGA 508 ALAL+ R +M GA Sbjct: 495 AALALSTR--VMQGA 507 >ref|YP_004754593.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Collimonas fungivorans Ter331] gb|AEK63770.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Collimonas fungivorans Ter331] Length = 511 Score = 628 bits (1619), Expect = e-178, Method: Compositional matrix adjust. Identities = 335/507 (66%), Positives = 386/507 (76%), Gaps = 9/507 (1%) Query: 7 NLHDIQRTLRQAAPS-AQLTSDSRRVAPGDVFFAYVGDA-DGRSYIADAVERGAAAVVYE 64 L +IQ+ L AP+ A+L SDSR+V GDVFFAY GDA DGR+YIA A+E GA+AV+YE Sbjct: 8 QLPEIQQWLDSVAPAGAELVSDSRKVKAGDVFFAYPGDAADGRAYIAQALENGASAVLYE 67 Query: 65 AAGFTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIA 124 F W V H AV+ LK +GEIA +Y Q D+ ML VAVTGTNGKTSC WLG A Sbjct: 68 KEKFAWDTAWRVAHRAVSGLKLLSGEIAHGYYDQADKDMLVVAVTGTNGKTSCTQWLGHA 127 Query: 125 LSRLAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIE 184 LS L A+ GVIGTLG G ++ G+ F+ TG TTPDA+LLQ++L + + V ALAIE Sbjct: 128 LSHLGQAT--GVIGTLGTGIYMQGERGEFEETGNTTPDALLLQQALSNMRRQGVAALAIE 185 Query: 185 ASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDD 244 ASSIGL QGR+NGMHVD+AL TNFTRDHLD+HGD Q YE AKR LF WPGL+ AV+NLDD Sbjct: 186 ASSIGLEQGRLNGMHVDIALFTNFTRDHLDYHGDEQHYEAAKRMLFDWPGLQQAVINLDD 245 Query: 245 DMGQRLLPLLAERK--VPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPFGS 302 MG RL+ L +++ +PVIGY + Q GV LRAS +R++ GT FHVDSPFGS Sbjct: 246 AMGLRLIDHLRQKQPAIPVIGYTCEELQA--VPGVQVLRASAIRTNANGTAFHVDSPFGS 303 Query: 303 GQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLIVI 362 QVKTQLVG+FNVSN LGI+GVLL +GVAWDA + A L PGRMQQFGG D PLIVI Sbjct: 304 AQVKTQLVGQFNVSNALGILGVLLAKGVAWDAALNAIELLVAVPGRMQQFGGHDAPLIVI 363 Query: 363 DYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLTSD 422 DYAHTPDALDKTL+TLRQ+A QR GQLWCVFGCGGDRDPGKRPQMG +AE AD V++TSD Sbjct: 364 DYAHTPDALDKTLNTLRQVAQQRNGQLWCVFGCGGDRDPGKRPQMGAVAELADHVIVTSD 423 Query: 423 NPRSEDPQAIIDQIRAGMSRVEPV-VLPDRAGAILWAIRHATKADVVLLAGKGHESYQEI 481 NPRSE+P II QI AGM + L DRA AILWA+RHA KADVVLLAGKGHE+YQEI Sbjct: 424 NPRSEEPSLIIGQILAGMKAPQAAQALEDRAAAILWAVRHAAKADVVLLAGKGHETYQEI 483 Query: 482 AGKKLPFLDADHVALALAARSTMMGGA 508 GKKLPFLDADH ALALAAR+TM GGA Sbjct: 484 KGKKLPFLDADHTALALAARATMKGGA 510 >ref|YP_001101051.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Herminiimonas arsenicoxydans] emb|CAL62930.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-tripeptide synthetase) [Herminiimonas arsenicoxydans] Length = 508 Score = 598 bits (1543), Expect = e-169, Method: Compositional matrix adjust. Identities = 302/481 (62%), Positives = 366/481 (76%), Gaps = 10/481 (2%) Query: 26 SDSRRVAPGDVFFAYVGD-ADGRSYIADAVERGAAAVVYEAAGFTWPAQIDVPHLAVTDL 84 SDSR + GDVF AY GD ADGR+YI+DA+ERGA A++Y+AAG W + +VPHLA+ +L Sbjct: 27 SDSRSIGKGDVFLAYPGDEADGRTYISDAIERGAQAILYDAAGCNWDEEWNVPHLAIDNL 86 Query: 85 KSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIALSRLAGASTAGVIGTLGVGS 144 ++ AG IAA++YG PD M TVAVTGTNGKTSC+ WLG ALSRL G TA VIGTLGVG Sbjct: 87 RACAGFIAAAYYGHPDHTMFTVAVTGTNGKTSCSQWLGNALSRL-GQPTA-VIGTLGVGI 144 Query: 145 FVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIEASSIGLAQGRMNGMHVDVAL 204 F +G+ F+VTGYTTPDAVLLQR L + ALAIEASSIGL QGR+ G+H D+AL Sbjct: 145 FKHGEHGTFNVTGYTTPDAVLLQRELVNMHHAGATALAIEASSIGLHQGRLYGVHFDMAL 204 Query: 205 LTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDDDMGQRLLPLLAERK--VPVI 262 TNFTRDHLD+HGDM YE AK LF WPGL+HAVVNLDD +G RL+ L R+ + + Sbjct: 205 FTNFTRDHLDYHGDMAAYEAAKTMLFDWPGLRHAVVNLDDALGVRLVERLKRRQSGIGIT 264 Query: 263 GYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPFGSGQVKTQLVGRFNVSNVLGIM 322 GY + ++ D + L AS +RS+H GT F + S FG VKTQLVG FNVSNVLGI+ Sbjct: 265 GYTLTNQGVAD---IDLLSASDIRSTHAGTSFQLTSKFGVTLVKTQLVGEFNVSNVLGII 321 Query: 323 GVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLIVIDYAHTPDALDKTLSTLRQLA 382 G+LL +G+A VVAA AL+ PGRMQQ GG + PL+VIDYAHTPDAL+KTL+TLR++A Sbjct: 322 GILLAKGIALSNVVAAIEALTSVPGRMQQLGGAEAPLVVIDYAHTPDALEKTLATLREVA 381 Query: 383 TQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLTSDNPRSEDPQAIIDQIRAGM-- 440 +RGG LWCVFGCGGDRD GKRPQMG+ A AD +++TSDNPR E+P +II QI AGM Sbjct: 382 NERGGALWCVFGCGGDRDAGKRPQMGKAAMAADHIIVTSDNPRHEEPASIIAQIVAGMDV 441 Query: 441 SRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQEIAGKKLPFLDADHVALALAA 500 ++ P ++ DRA AIL+A RHA K DV+LLAGKGHE+YQEI G+K PFLDADH ALAL+A Sbjct: 442 AKNAPHIMEDRAKAILYAGRHAAKQDVILLAGKGHEAYQEIKGRKQPFLDADHAALALSA 501 Query: 501 R 501 R Sbjct: 502 R 502 >ref|ZP_08272723.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Oxalobacteraceae bacterium IMCC9480] gb|EGF33794.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Oxalobacteraceae bacterium IMCC9480] Length = 509 Score = 558 bits (1439), Expect = e-157, Method: Compositional matrix adjust. Identities = 303/492 (61%), Positives = 349/492 (70%), Gaps = 15/492 (3%) Query: 6 LNLHDIQRTLRQAAPSAQLTSDSRRVAPGDVFFAYVGDA-DGRSYIADAVERGAAAVVYE 64 +N I LR AP+A+L+SDSR + GDVFFAY GDA DGR +I DA+ERGA AVV E Sbjct: 3 MNPEHIVDWLRATAPAAELSSDSRSIVAGDVFFAYPGDAADGRRFIDDAIERGAVAVVCE 62 Query: 65 AAGFTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIA 124 A G W D P LAVT LK+HAG +AA WYGQ D G+ TVA+TGTNGKTSC+ WL A Sbjct: 63 ADGLVWHGAADFPLLAVTGLKAHAGRVAALWYGQADAGLFTVAITGTNGKTSCSQWLAAA 122 Query: 125 LSRLAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIE 184 LSRL G VIGTLG G F G TGYTTPDA+LLQR L L + ALAIE Sbjct: 123 LSRLTG--PCAVIGTLGTGLFRRGSVDRLAETGYTTPDAILLQRRLRDLRRAGASALAIE 180 Query: 185 ASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDD 244 ASSIGL QGR+NG+ V VAL TNFTRDHLD+HGDM TYE AK LF PGL+HAV+NLDD Sbjct: 181 ASSIGLDQGRLNGLPVQVALFTNFTRDHLDYHGDMATYEAAKTALFDQPGLQHAVLNLDD 240 Query: 245 DMGQRLLPLLAERKVP---VIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPFG 301 MG RLL L +R P + GY + D Q P G+ LRA +RSSH GT F + + G Sbjct: 241 AMGLRLLAHL-QRTAPQLALTGYTLTDLQ---PAGITVLRAGDIRSSHAGTSFQLMTAAG 296 Query: 302 SGQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLIV 361 + V+T+LVG FNVSNVLGI+GVLL Q A+V A L+ PGRMQQFGG D PL+V Sbjct: 297 TMLVRTRLVGSFNVSNVLGIIGVLLAQDCPLRAIVDAIETLTAVPGRMQQFGGQDAPLVV 356 Query: 362 IDYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLTS 421 IDYAHTPDALDKTL+ L+Q+A QR G+LWCVFGCGGDRDPGKRPQMG A AD++++TS Sbjct: 357 IDYAHTPDALDKTLAALQQVAAQRHGKLWCVFGCGGDRDPGKRPQMGLAALAADEIIITS 416 Query: 422 DNPRSEDPQAIIDQIRAGM-----SRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHE 476 DNPRSE AII Q G S P+V+ DRA AILWA+RHA ADV+LLAGKGHE Sbjct: 417 DNPRSEVAAAIIAQTLQGTDERADSHAVPLVIEDRAAAILWAVRHAANADVILLAGKGHE 476 Query: 477 SYQEIAGKKLPF 488 +YQEI GKKLPF Sbjct: 477 NYQEIRGKKLPF 488 >ref|ZP_04579654.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Oxalobacter formigenes OXCC13] gb|EEO30627.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Oxalobacter formigenes OXCC13] Length = 503 Score = 550 bits (1416), Expect = e-154, Method: Compositional matrix adjust. Identities = 280/504 (55%), Positives = 361/504 (71%), Gaps = 11/504 (2%) Query: 3 ERALNLHDIQRTLRQAAPSAQLTSDSRRVA--PGDVFFAYVGD-ADGRSYIADAVERGAA 59 ++AL L I + ++ P+ QL SDSR + VFFAY GD ADGR+YIA A+E GA Sbjct: 2 DKALQLMPIVQWIKGICPNGQLFSDSREIKYETDAVFFAYEGDSADGRNYIARAIESGAK 61 Query: 60 AVVYEAAGFTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAY 119 AVVYE++ F W V HL V LK++AG IA ++YG P + M +AVTGTNGKTS Sbjct: 62 AVVYESSDFEWNPDWKVDHLGVVGLKANAGPIADAFYGSPARSMSIIAVTGTNGKTSTTQ 121 Query: 120 WLGIALSRLAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVG 179 W+ ALSRL G TA VIGTLGV F NG+ + TGYTTPD V LQR L L V Sbjct: 122 WIAQALSRL-GRKTA-VIGTLGVSIFENGESGASEETGYTTPDQVQLQRILADLHSREVK 179 Query: 180 ALAIEASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAV 239 +AIEASSIG+ QGR+NG+ +D+AL TNFTRDHLD+H DM +Y+ AKR+LF W GLKHAV Sbjct: 180 CVAIEASSIGIDQGRLNGLTIDIALFTNFTRDHLDYHHDMASYKAAKRRLFGWKGLKHAV 239 Query: 240 VNLDDDMGQRLLPLLAERKVPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSP 299 VNLDD MG L L + K+ + GY+I G +P L A +R+ G F ++SP Sbjct: 240 VNLDDAMGIELASEL-KSKMALTGYSI----NGARADIPVLNAVDIRNRTHGDEFRIESP 294 Query: 300 FGSGQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPL 359 +G +++TQL+GRFNVSNVLG++GVLL G+ WD+ V + +L+ PGRMQQ GG + PL Sbjct: 295 YGDSKIRTQLIGRFNVSNVLGVLGVLLANGIDWDSAVQSLTSLAAPPGRMQQMGGKEAPL 354 Query: 360 IVIDYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVL 419 +VID+AHTPDAL+K LSTLR +A R G+LWC+FGCGGDRD GKRP+MG+ AE AD +++ Sbjct: 355 VVIDFAHTPDALEKGLSTLRHVADDRNGKLWCIFGCGGDRDHGKRPEMGEKAESADVIIV 414 Query: 420 TSDNPRSEDPQAIIDQIRAGMSRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQ 479 TSDNPRSEDP+ I+++I +GM++ +P+ + DRA AIL A++ A+K DV+ +AGKGHE+YQ Sbjct: 415 TSDNPRSEDPKKIMEEIVSGMTK-DPIQVEDRATAILTAVKQASKNDVIFVAGKGHEAYQ 473 Query: 480 EIAGKKLPFLDADHVALALAARST 503 E+ G K PF DADHVALALA+R T Sbjct: 474 EVKGVKRPFADADHVALALASRLT 497 >ref|ZP_04577501.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Oxalobacter formigenes HOxBLS] gb|EEO28463.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Oxalobacter formigenes HOxBLS] Length = 504 Score = 545 bits (1404), Expect = e-153, Method: Compositional matrix adjust. Identities = 285/496 (57%), Positives = 354/496 (71%), Gaps = 11/496 (2%) Query: 11 IQRTLRQAAPSAQLTSDSRRV-APGD-VFFAYVGD-ADGRSYIADAVERGAAAVVYEAAG 67 + R LR P+ QL SDSR + A G+ VFFAY GD ADGR YI+ A+ GA AVV+E G Sbjct: 11 VVRWLRAVCPNGQLFSDSREIGADGNAVFFAYEGDSADGRDYISKAIGNGAKAVVFEKEG 70 Query: 68 FTWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIALSR 127 F W + +VPHL V LK+ A +AA++Y P Q M +AVTGTNGKTSC WLG +LS Sbjct: 71 FDWNPEWNVPHLGVMGLKACAASVAAAYYDYPAQAMFVIAVTGTNGKTSCTQWLGQSLSA 130 Query: 128 LAGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIEASS 187 L G TA VIGTLGV FVNG+ + TGYTTPD V LQR L KL + V +A+EASS Sbjct: 131 L-GKKTA-VIGTLGVTVFVNGQGGVPEETGYTTPDQVQLQRILAKLRKESVQCVAMEASS 188 Query: 188 IGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDDDMG 247 IG+ QGR+NG+ +DV L TNFTRDHLD+H DM +Y+ AKRKLF WPGLKHAV+NLDD MG Sbjct: 189 IGIDQGRLNGIPIDVGLFTNFTRDHLDYHHDMASYKAAKRKLFDWPGLKHAVLNLDDPMG 248 Query: 248 QRLLPLLAERKVPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPFGSGQVKT 307 + L L R + + GY + + +P L+A +R +G F +DS GS +++T Sbjct: 249 RELATALKTR-ISLTGYTLENAD----TAIPVLKACDIRHRTSGIEFSIDSFSGSARIRT 303 Query: 308 QLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLIVIDYAHT 367 +L+GRFN SNVLG++GVLL G+ WD V L P GRMQQ GG + PL+VID+AHT Sbjct: 304 RLIGRFNASNVLGVLGVLLAAGIHWDDAVRTLGDLLPPAGRMQQMGGKNAPLVVIDFAHT 363 Query: 368 PDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQADQVVLTSDNPRSE 427 PDA++K L+TLR +A +R G+LWCVFGCGGDRD GKRPQMG ++E AD V++TSDNPRSE Sbjct: 364 PDAMEKGLATLRHVANERNGKLWCVFGCGGDRDQGKRPQMGSVSETADFVIVTSDNPRSE 423 Query: 428 DPQAIIDQIRAGMSRVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQEIAGKKLP 487 DP+ I+ QI +GM + EP V DRA AIL A+R A++ DV+ LAGKGHE+YQEI G KLP Sbjct: 424 DPKEIMKQIISGMEK-EPQVYEDRAMAILQAVRQASQNDVIFLAGKGHETYQEIKGVKLP 482 Query: 488 FLDADHVALALAARST 503 F DADHVALALA+R T Sbjct: 483 FADADHVALALASRVT 498 >ref|YP_727720.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Ralstonia eutropha H16] emb|CAJ94352.1| UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase [Ralstonia eutropha H16] Length = 520 Score = 473 bits (1216), Expect = e-131, Method: Compositional matrix adjust. Identities = 277/498 (55%), Positives = 332/498 (66%), Gaps = 23/498 (4%) Query: 19 APSAQLTSDSRRVAPGDVFFAYV-GDA----DGRSYIADAVERGAAAVVYEAAGFTWPAQ 73 A +AQLT D+RR+A GDVFFAYV G+A DGR YIA A+ GA A+VYEA GF WP Sbjct: 27 AAAAQLTGDTRRLARGDVFFAYVLGNARLATDGRLYIAQAIAAGAGAIVYEADGFDWPFS 86 Query: 74 IDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIALSRLAGAST 133 VPHLAV+ L AG IAA W+G P +G+ +TGTNGKTSC+ WL L A + Sbjct: 87 DVVPHLAVSHLHQLAGPIAAGWHGNPVRGLAVTGITGTNGKTSCSQWLARVLQ--AAGTP 144 Query: 134 AGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIEASSIGLAQG 193 IGTLG G P TG+TTPDAV LQ SL L A+A+E SS GL Q Sbjct: 145 CATIGTLGTGF-----PGALQATGFTTPDAVQLQASLASLHDAGARAVAMEVSSHGLEQE 199 Query: 194 RMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDDDMGQRLLPL 253 R+ G H VA+LTN T+DHLD+HG M YE AK LF+W GL+ AVVN DD MGQRLL Sbjct: 200 RVAGTHFSVAVLTNLTQDHLDYHGSMAEYEAAKESLFRWDGLRTAVVNRDDAMGQRLLAA 259 Query: 254 LAERKVP--VIGYAIADEQGGDPHGVPT---LRASQLRSSHTGTVFHVDSPFGSGQVKTQ 308 A VI Y I D G P LRA+ +R++ TGT FH+D FGS ++ T Sbjct: 260 DAAAIGAPHVIEYGI-DGPGAATVRRPRGEWLRATNVRATPTGTAFHIDGSFGSAEMATP 318 Query: 309 LVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQF---GGPDVPLIVIDYA 365 ++G FNVSN+L ++G L GVAWDA +AA AL+P GRM+ F GGPD PL V+DYA Sbjct: 319 MIGAFNVSNLLAVLGAALANGVAWDAAIAALRALTPVEGRMELFGAAGGPDAPLAVVDYA 378 Query: 366 HTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAE-QADQVVLTSDNP 424 HTPDAL +TL+ LR +A R G+LWCVFGCGGDRDP KRP MG +AE +AD+V+LTSDNP Sbjct: 379 HTPDALAQTLAALRPVAQARNGRLWCVFGCGGDRDPIKRPLMGAVAEREADEVILTSDNP 438 Query: 425 RSEDPQAIIDQIRAGMS-RVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQEIAG 483 RSEDPQ I+D I GM+ R + DRA AIL+A+RHA ADVVL+AGKGHE+ QEI G Sbjct: 439 RSEDPQDILDAIADGMAVRARARQIEDRAAAILYAVRHAAPADVVLVAGKGHEATQEIQG 498 Query: 484 KKLPFLDADHVALALAAR 501 +K PF D +HV LALA R Sbjct: 499 RKRPFSDREHVRLALATR 516 >ref|YP_585274.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Cupriavidus metallidurans CH34] gb|ABF10005.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-diaminopimelate ligase [Cupriavidus metallidurans CH34] Length = 515 Score = 473 bits (1216), Expect = e-131, Method: Compositional matrix adjust. Identities = 271/497 (54%), Positives = 330/497 (66%), Gaps = 17/497 (3%) Query: 15 LRQAAP-SAQLTSDSRRVAPGDVFFAYV-GD----ADGRSYIADAVERGAAAVVYEAAGF 68 LR AP +AQLT D+RR+ PGDVFFAYV G+ DGR +I A+ GA+A+VYEA F Sbjct: 22 LRTHAPENAQLTGDTRRLQPGDVFFAYVLGNERLATDGRPHIDKAIAAGASAIVYEADNF 81 Query: 69 TWPAQIDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIALSRL 128 WP VPHLAV+ L AG IAA WYG + VTGTNGKTSC+ WL L ++ Sbjct: 82 AWPHDDRVPHLAVSHLHELAGPIAAGWYGIAACNLTIAGVTGTNGKTSCSQWLA-RLLQM 140 Query: 129 AGASTAGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIEASSI 188 AG A IGTLG +G P +TG+TTPDAV LQ SL +L A+A+E SS Sbjct: 141 AGTRCA-TIGTLG-----SGFPDALKLTGFTTPDAVQLQASLAELHDAGARAVAMEVSSH 194 Query: 189 GLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDDDMGQ 248 GL QGR+ G VA+LTN T+DHLD+HG M YE AK +LF W GLK AV+N DD MGQ Sbjct: 195 GLEQGRVAGTGFAVAVLTNLTQDHLDYHGTMAEYEAAKARLFAWDGLKAAVINRDDGMGQ 254 Query: 249 RLLP--LLAERKVPVIGYAIADEQGGDPHGVPTLRASQLRSSHTGTVFHVDSPFGSGQVK 306 RLL +A VI Y I + G LRA+ +R++ GT FHVD FG+ V Sbjct: 255 RLLASNAVAVSAPQVIEYGIDGKAGASVARGQWLRATGVRATGAGTAFHVDGSFGTADVT 314 Query: 307 TQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQFGGPDVPLIVIDYAH 366 T ++G FNVSN+L ++G L QGV WDA + A L+P GRM+ FGG D PL V+DYAH Sbjct: 315 TPMIGAFNVSNLLAVLGAALAQGVTWDAAIDALRRLTPVDGRMELFGGHDAPLAVVDYAH 374 Query: 367 TPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAEQ-ADQVVLTSDNPR 425 TPDAL +TL+ LR +A R G+LWCVFGCGGDRD KRP MG +AE+ AD+VVLTSDNPR Sbjct: 375 TPDALVQTLTALRPVAQARQGKLWCVFGCGGDRDATKRPLMGGVAERLADEVVLTSDNPR 434 Query: 426 SEDPQAIIDQIRAGMS-RVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQEIAGK 484 SEDP+ I++ I GMS R ++ DRA AIL+AI+HA ADVVL+AGKGHE+ QEI G+ Sbjct: 435 SEDPREILEAIADGMSDRARAALIEDRAAAILYAIKHAAPADVVLVAGKGHEATQEIQGR 494 Query: 485 KLPFLDADHVALALAAR 501 K PF D +HV L L AR Sbjct: 495 KRPFSDREHVRLTLGAR 511 >ref|YP_004687007.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE [Cupriavidus necator N-1] gb|AEI78526.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE [Cupriavidus necator N-1] Length = 520 Score = 466 bits (1199), Expect = e-129, Method: Compositional matrix adjust. Identities = 272/498 (54%), Positives = 330/498 (66%), Gaps = 23/498 (4%) Query: 19 APSAQLTSDSRRVAPGDVFFAYV-GD----ADGRSYIADAVERGAAAVVYEAAGFTWPAQ 73 A +AQLT D+RR+A GDVFFAYV G+ DGR YIA A+ GA A+V+EA GF WP Sbjct: 27 AAAAQLTGDTRRLARGDVFFAYVLGNERLATDGRPYIAQAIAAGAGAIVHEADGFDWPFG 86 Query: 74 IDVPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSCAYWLGIALSRLAGAST 133 VPHLAV+ L AG IAA W+G P +G+ +TGTNGKTSC+ WL L A + Sbjct: 87 DVVPHLAVSRLHQLAGPIAAGWHGNPVRGLAVTGITGTNGKTSCSQWLARVLQ--AAGTP 144 Query: 134 AGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKLAQGRVGALAIEASSIGLAQG 193 IGTLG G P TG+TTPDAV LQ SL L A+A+E SS GL Q Sbjct: 145 CATIGTLGTGF-----PGALQATGFTTPDAVQLQASLASLHDAGARAVAMEVSSHGLEQE 199 Query: 194 RMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWPGLKHAVVNLDDDMGQRLLPL 253 R+ G H VA+LTN T+DHLD+HG M YE AK LF+W GL+ AV+N DD MGQRLL Sbjct: 200 RVAGTHFSVAVLTNLTQDHLDYHGSMAEYEAAKESLFRWDGLRTAVINRDDAMGQRLLAA 259 Query: 254 LAERKVP--VIGYAIADEQGGD---PHGVPTLRASQLRSSHTGTVFHVDSPFGSGQVKTQ 308 A VI Y I P G LRA+ +R++ TGT FH+D FGS ++ T Sbjct: 260 DAAAIGAPHVIEYGIDGPDAATVRRPRG-EWLRATNVRATPTGTAFHIDGSFGSAEMATP 318 Query: 309 LVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQF---GGPDVPLIVIDYA 365 ++G FNVSN+L ++G L GVAWDA +AA AL+P GRM+ F GGPD PL V+DYA Sbjct: 319 MIGAFNVSNLLAVLGAALANGVAWDAAIAALRALTPVEGRMELFGAAGGPDAPLAVVDYA 378 Query: 366 HTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAE-QADQVVLTSDNP 424 HTPDAL +TL+ LR +A R G+LWCVFGCGGDRDP KRP MG +AE +AD+V+LTSDNP Sbjct: 379 HTPDALAQTLAALRPVAQARNGRLWCVFGCGGDRDPIKRPLMGAVAEREADEVILTSDNP 438 Query: 425 RSEDPQAIIDQIRAGMS-RVEPVVLPDRAGAILWAIRHATKADVVLLAGKGHESYQEIAG 483 RSEDPQ I+D I GM+ R + DRA AIL+A++HA ADVVL+AGKGHE+ QEI G Sbjct: 439 RSEDPQDILDAIADGMAERARARQIEDRAAAILYAVKHAAPADVVLVAGKGHEATQEIQG 498 Query: 484 KKLPFLDADHVALALAAR 501 +K PF D +HV LALA R Sbjct: 499 RKRPFSDREHVRLALATR 516