BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0008.p (332 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775750.1| non-ribosomal peptide synthetase [Herbaspiri... 536 e-150 ref|ZP_01127429.1| probable peptide synthetase protein [Nitrococ... 290 3e-76 ref|YP_002799713.1| peptide synthase [Azotobacter vinelandii DJ]... 227 2e-57 ref|ZP_08494735.1| amino acid adenylation domain protein [Microc... 221 2e-55 ref|YP_631823.1| non-ribosomal peptide synthetase [Myxococcus xa... 220 2e-55 gb|AAX16327.1| PvdI(3) [Pseudomonas aeruginosa] 218 1e-54 gb|AAX16314.1| PvdI(3) [Pseudomonas aeruginosa] 218 1e-54 ref|YP_002440486.1| PvdI(3) [Pseudomonas aeruginosa LESB58] >gi|... 218 1e-54 ref|ZP_05029367.1| amino acid adenylation domain protein [Microc... 218 2e-54 ref|YP_001520888.1| nonribosomal protein synthetase [Acaryochlor... 215 8e-54 >ref|YP_003775750.1| non-ribosomal peptide synthetase [Herbaspirillum seropedicae SmR1] gb|ADJ63842.1| non-ribosomal peptide synthetase protein [Herbaspirillum seropedicae SmR1] Length = 9160 Score = 536 bits (1380), Expect = e-150, Method: Compositional matrix adjust. Identities = 276/279 (98%), Positives = 277/279 (99%) Query: 1 MSRPPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHA 60 MSRPPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHA Sbjct: 5190 MSRPPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHA 5249 Query: 61 ILRTRFAETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAG 120 ILRTRFAETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAG Sbjct: 5250 ILRTRFAETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAG 5309 Query: 121 QLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYA 180 QLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYA Sbjct: 5310 QLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYA 5369 Query: 181 DYAHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSAL 240 DYAHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSAL Sbjct: 5370 DYAHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSAL 5429 Query: 241 AQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 AQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQ+DF G Sbjct: 5430 AQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQSDFLVG 5468 Score = 141 bits (356), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 98/267 (36%), Positives = 133/267 (49%), Gaps = 2/267 (0%) Query: 19 WFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE-TDGLPYQQA 77 W Q P ++ A L G +D L AL L ARH ILRT F E DG P Sbjct: 3270 WTACQARPMRPPTTMSAALMLEGVVDAVLLEQALRLLVARHDILRTGFGEDADGNPVA-T 3328 Query: 78 VPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIALGPQEHVLV 137 + PF L DL LPP QR+ +L ++ AA F L Q L L+ L Q+ VL+ Sbjct: 3329 LHPFDFSLEQHDLAALPPPQRDLQLDRLRRSHAAARFALRQPPLLRAALVRLASQQQVLL 3388 Query: 138 IGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQRVQGAWLAD 197 + +HHIV+D WS L++ ++A AY + P LP+QYADYA WQ L D Sbjct: 3389 LAIHHIVADGWSVALMMEEIAAAYSALQEGRSYAPPPLPLQYADYAAWQVAGAGSRMLED 3448 Query: 198 ELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCRAQHCTPFV 257 + +W D L V ++ LP+ RPRPAR ++ G L + L +QA R + T + Sbjct: 3449 SIAWWRDALAGVPATPYLPSTRPRPARATYAGQRLRMHLPAHLRSGVQALARREGVTAYA 3508 Query: 258 ALMAAWQVLLSRYSGQADFARGRGAVG 284 L+A++ LL + SG DF G G Sbjct: 3509 VLLASFAWLLHQRSGAGDFVVGTDVAG 3535 Score = 136 bits (343), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 104/275 (37%), Positives = 135/275 (49%), Gaps = 6/275 (2%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PL+ +QQ LW Q +P AYNL L G L AL AL L ARHA LRT F Sbjct: 692 PLTQAQQGLWLTWQLQPDSAAYNLAGVLDLRGELQVEALEDALCDLAARHAALRTLFPLR 751 Query: 70 DGLPYQQAVPPFPVQLAWL--DLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLI 127 DG P QQ + + L DLR+ P +R Q LQ A F L L L+ Sbjct: 752 DGTPVQQVLDIDEARPMLLRSDLRRQPADKRAQAAASALQRFHAQAFRLDSETPLRAMLV 811 Query: 128 ALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQA-QLPALPMQYADYAHWQ 186 L P L + +HHI +D WS +++ +L AY +AR G A PAL +Q DYA WQ Sbjct: 812 QLEPHHFRLGLCIHHIAADGWSLGIILDELTAAY-EARCAGAAPSWPALELQPGDYAVWQ 870 Query: 187 RQRVQ--GAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQM 244 RQR Q +L YW L + L LPTDRPR A H + L +AL+ + Sbjct: 871 RQRSQPGSPEFQRQLDYWRARLEGAPALLPLPTDRPRQAGAHGGEGQHRWRLSAALSTAL 930 Query: 245 QAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + +Q T + A++A + + L R SGQ+D G Sbjct: 931 RKLAASQGVTLYGAVLALFTLALQRLSGQSDLCVG 965 Score = 94.0 bits (232), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 92/287 (32%), Positives = 124/287 (43%), Gaps = 16/287 (5%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS Q + F +EPG +AY + G LD A A A H ILRT F Sbjct: 6743 PLSPMQAGMLFHSVFEPGGSAYINQLRVDIDG-LDAARFEQAWQDTVAAHDILRTGFLHQ 6801 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAA----AHVFDLGQAGQLDVR 125 P Q L+ LD R Q L EL A A A FDL + + Sbjct: 6802 P-RPLQWVARRVASPLSQLDWRD---AAAGQSLGGELDALAQRQLAQGFDLAAPPLMRLV 6857 Query: 126 LIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHW 185 L+ G Q H L+ +HH++ D WS +++ ++ Y QA GQA+ L ++Y DY W Sbjct: 6858 LVRTGAQRHHLIWTVHHLLLDGWSTSMLLGEVLRRYAQATAAGQAKPTKLALRYRDYIGW 6917 Query: 186 QRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQ 245 + R Q A R+W+ L + L PRP+ H LD+AL ++ Sbjct: 6918 LQGRDQEA----TRRFWEIQLARLQQPTRLADAMPRPSTPESGHGEHRELLDAALTARLN 6973 Query: 246 AFCRAQHCTPFVALMAAWQVLLSRYSGQADFARGRGAVGGAGCAAGP 292 RAQ T + AAW +LL RY+ A +G V GA A P Sbjct: 6974 EAARAQRITLNTLVQAAWALLLQRYTYA---AHDQGVVFGATVAGRP 7017 Score = 68.2 bits (165), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 84/285 (29%), Positives = 121/285 (42%), Gaps = 29/285 (10%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFA-E 68 PLS QQ + F PG Y + R+ G LD A + A ++ ARH ++RT F + Sbjct: 7815 PLSPMQQGMLFHTMESPGSGLYVNQLSVRVEG-LDEARFAQAWQSVLARHPVMRTGFLWQ 7873 Query: 69 TDGLPYQQAV---PPFPVQLA-WLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDV 124 D QAV F +++ W +P +R AA + Sbjct: 7874 ADYAQPLQAVWRTLAFGIEVQDWSARATMPSCRRRLPPLRRPILRAAST--CCNRPLVRA 7931 Query: 125 RLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAH 184 L+ LGP +H LV MHHI+ D WS ++++L AY G LPA YA Y Sbjct: 7932 TLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAY------GGQPLPAPGPDYAQYIG 7985 Query: 185 W----QRQRVQGAWLADELRYWDDYLGPVNS-SLDLPTDRPRPARQSFRGAVHAFTLDSA 239 W Q Q RYW L ++ SL RP PAR+ F G ++ D+A Sbjct: 7986 WLATLDPQAAQ--------RYWMGALQALDGPSLLAEGVRPDPARRGF-GKLYGHC-DAA 8035 Query: 240 LAQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARGRGAVG 284 ++++ F R+Q T + AW + L+R+ A G G Sbjct: 8036 ATRRLEQFARSQRVTLNTLVQGAWSLALARHKRSTAVAFGATVSG 8080 >ref|ZP_01127429.1| probable peptide synthetase protein [Nitrococcus mobilis Nb-231] gb|EAR21796.1| probable peptide synthetase protein [Nitrococcus mobilis Nb-231] Length = 2660 Score = 290 bits (741), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 156/272 (57%), Positives = 182/272 (66%), Gaps = 1/272 (0%) Query: 9 APLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE 68 APLS++QQ+LWFLQ Y P TAYNLTRA RL G LD L A AL ARHAILRT F + Sbjct: 32 APLSFAQQRLWFLQHYAPEATAYNLTRALRLRGVLDADGLECAFRALIARHAILRTYFED 91 Query: 69 TDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 DG P Q +P P L DL L REQ L++ +QA A H FDL A L L+ Sbjct: 92 CDGEPRQIVLPEVPFTLVREDLSPLSEAVREQALKDRIQAEADHPFDLRVAPLLRATLLR 151 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARR-DGQAQLPALPMQYADYAHWQR 187 LG +EHVL++G+HHIVSDAWSNP++ RDLA AYR A LP LP+QYADYA WQR Sbjct: 152 LGDEEHVLLLGLHHIVSDAWSNPVLTRDLAAAYRAALVGKADVNLPPLPVQYADYAIWQR 211 Query: 188 QRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAF 247 + +QGA L + YW DYLG L+LPTDR RPARQ+ RG F L S L Q +Q F Sbjct: 212 ECLQGAPLEAAIGYWRDYLGEHLPGLELPTDRSRPARQTSRGGSIRFLLPSTLIQLVQEF 271 Query: 248 CRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 CRA+ CTPFV L+AAWQ+LLSRYSGQ +FA G Sbjct: 272 CRAEGCTPFVVLLAAWQILLSRYSGQEEFAIG 303 Score = 204 bits (518), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 120/270 (44%), Positives = 159/270 (58%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLSY+Q +LWFL Q EP AYN+ A RL G LD AL +AL RH LRT F Sbjct: 2167 PLSYAQSRLWFLWQLEPQSAAYNMPGAMRLKGRLDTQALQHTFNALLKRHEGLRTTFRGE 2226 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 DG PYQ V++A DL P R+ + +A A FDL + V+L+ L Sbjct: 2227 DGQPYQIINEATSVEIALEDLGVYPEADRDAAARASAEAEAKAPFDLEAGPLVRVKLLRL 2286 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 Q+HVL++ MHHIVSD WS LVI + A Y + + +LP LP+QYADYA WQRQ Sbjct: 2287 AEQDHVLLVTMHHIVSDGWSMNLVIGEFAALYEAYSQGLEPRLPTLPIQYADYALWQRQW 2346 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 ++ +L YW LG + SL+LP+DRPR A S RGA H FT+DS L Q+++AF + Sbjct: 2347 MEAGERERQLAYWRAQLGEHHPSLELPSDRPRSALPSHRGANHRFTIDSELTQRLKAFAQ 2406 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 A T F+ L+AA+ ++L + S Q++F G Sbjct: 2407 AHDVTLFMLLLAAFSIVLKQNSRQSEFLVG 2436 Score = 191 bits (484), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 120/272 (44%), Positives = 162/272 (59%), Gaps = 2/272 (0%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLSY+Q +LWFL Q EP +AYN+ A RL G LD AL A D L RH +LRT F Sbjct: 1103 PLSYAQSRLWFLWQLEPQSSAYNVPGAIRLKGELDIGALGKAFDFLVKRHEVLRTTFHRA 1162 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPP--QQREQRLQEELQAAAAHVFDLGQAGQLDVRLI 127 G Q P P++L DL + ++RE+R+ E +A A FDL + L VRL+ Sbjct: 1163 SGEVIQTVQLPAPIELDREDLGEACARVEERERRVIELAEAEAGGAFDLERGPLLRVRLL 1222 Query: 128 ALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQR 187 LG +EHVL++ +HHIV DAWS +++ + A AY R+ +L ALP+QYADYA WQR Sbjct: 1223 RLGAREHVLLVTLHHIVCDAWSMEVLVEEFARAYAAYRQGEAPELAALPIQYADYALWQR 1282 Query: 188 QRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAF 247 Q ++ +L YW LG + L+LPTDR R A S RG + F L++ L Q+++A Sbjct: 1283 QWMEAGEGERQLAYWRAQLGEHHPVLELPTDRARRAVPSERGRRYDFALEAELVQRLRAL 1342 Query: 248 CRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 RA T + L+AA++VLL RY+GQ D G Sbjct: 1343 ARAHEVTLPMLLLAAFKVLLYRYTGQGDLRVG 1374 >ref|YP_002799713.1| peptide synthase [Azotobacter vinelandii DJ] gb|ACO78738.1| Non-ribosomal peptide synthase, PvdJ(2)-like protein [Azotobacter vinelandii DJ] Length = 4747 Score = 227 bits (578), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 120/268 (44%), Positives = 168/268 (62%) Query: 7 EHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRF 66 E LSY+QQ++WFL Q +P AYNL A RL G L+R AL A DAL RH LRTRF Sbjct: 48 ERQGLSYAQQRMWFLWQLDPQSPAYNLPMAVRLEGELERVALQDAFDALVTRHETLRTRF 107 Query: 67 AETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRL 126 + DG Q+ + P V + + DL L P ++++++ + Q A FDL +A L VRL Sbjct: 108 RQQDGGIRQEVLEPLSVTIGFEDLTALLPAKQDEQVSKLAQVEAMAPFDLAEAPLLRVRL 167 Query: 127 IALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQ 186 + L EHVL++ +HHIV+D WS L+I + Y A QA+LPALP+QY DYA WQ Sbjct: 168 LKLSDSEHVLLLTLHHIVADGWSLNLLIDEFIHLYDTACSGRQAELPALPIQYRDYALWQ 227 Query: 187 RQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQA 246 R ++ +L YW D LG ++SL+LPTDRPRPA S+RG H F ++ L+ Q++A Sbjct: 228 RSWLEAGERERQLIYWRDKLGGEHTSLELPTDRPRPAVPSYRGTRHEFRIEPLLSDQLRA 287 Query: 247 FCRAQHCTPFVALMAAWQVLLSRYSGQA 274 + + T F+ L+AA+++L+ RYSGQ+ Sbjct: 288 LAKRHNVTLFIVLLAAFKLLMQRYSGQS 315 Score = 196 bits (498), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 115/271 (42%), Positives = 158/271 (58%), Gaps = 6/271 (2%) Query: 12 SYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAETDG 71 SY+QQ+ WFL Q EPG AY++ A RL GALD AL + +AL RH LRT F + DG Sbjct: 3682 SYAQQRQWFLWQLEPGSAAYHIPAALRLKGALDIEALRRSFEALIRRHESLRTIFRQ-DG 3740 Query: 72 LPYQQAVPPFPVQLAWLDLRQLPPQQ---REQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 Q +PP W + LP ++R++ +++A +FDL Q L V+L+ Sbjct: 3741 ERTIQVIPPSGS--LWFEQEPLPADAAIGLDERIRVQVEAEVQRLFDLEQGPLLRVKLLR 3798 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQ 188 L +HVLV+ +HHIVSD WS PL++ +L Y + + +LP LP+QYADYA WQRQ Sbjct: 3799 LDEDDHVLVLTLHHIVSDGWSTPLMVDELVRLYEGYSQGHEVRLPELPVQYADYALWQRQ 3858 Query: 189 RVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 ++ +L YW LG L+LP DRPRPA Q++ GA A LD LA+ ++ Sbjct: 3859 WMEAGERDRQLAYWTAQLGGEQPVLELPGDRPRPAVQTYAGARLAVELDGELARSLRELA 3918 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 R + T F+ L+A++Q LL RYSGQ D G Sbjct: 3919 RREGVTLFMLLLASFQSLLHRYSGQDDIRVG 3949 Score = 193 bits (490), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 114/271 (42%), Positives = 155/271 (57%), Gaps = 6/271 (2%) Query: 12 SYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAETDG 71 SY+QQ+ WFL Q EPG AY++ A RL GALD AL + DAL RH LRT F + DG Sbjct: 1100 SYAQQRQWFLWQLEPGSAAYHIPAALRLKGALDIEALRRSFDALIRRHESLRTTFRQ-DG 1158 Query: 72 LPYQQAVPPFPVQLAWLDLRQLPPQQ---REQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 Q + P W + LP ++R++ +++A +FDL Q L V+L+ Sbjct: 1159 ERTLQVI--HPSGSLWFEQEPLPADAAIGLDERIRVQVEAEVQRLFDLEQGPLLRVKLLR 1216 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQ 188 L +HVL++ +HHIVSD WS P+++ +L Y + + LP LP+QYADYA WQRQ Sbjct: 1217 LDEDDHVLILSLHHIVSDGWSTPIMVDELVRLYEGYSQGHEVTLPELPVQYADYALWQRQ 1276 Query: 189 RVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 ++ +L YW LG L+LP DRPRPA QS GA A LD LA+ ++ Sbjct: 1277 WMEAGERDRQLAYWTAQLGGEQPVLELPGDRPRPAVQSHAGARLAVELDGELARSLRELA 1336 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 R + T F+ L+A++Q LL RYSGQ D G Sbjct: 1337 RREGVTLFMLLLASFQSLLHRYSGQDDIRVG 1367 Score = 75.5 bits (184), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 80/276 (28%), Positives = 111/276 (40%), Gaps = 14/276 (5%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS QQ + F E G + + + LD A AA A+ RH +LR F E Sbjct: 2625 PLSPMQQGMLFHSLLE-GEAGHYINQMRVDVEGLDVARFRAAWQAVVDRHEVLRASFVEV 2683 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 DG P Q + LD R P Q + L Q FDL + L + +I Sbjct: 2684 DGRPLQVIRRQVSMPCVELDWRSQP--QLQDSLDTWAQTDRQRGFDLEREPLLRLAVIRT 2741 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 G H L+ HHI+ D WS + ++ +AY + G L +Y DY W ++ Sbjct: 2742 GENRHHLIYTNHHILLDGWSGSQLQGEVLQAY-TGKPIGHPGL-----RYRDYIAWLGRQ 2795 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLP-TDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 + A A +W + LG + L + A + H D + + F Sbjct: 2796 DRAASEA----FWREQLGALEEPTRLAQAIKIDEAEKRAGHGDHQQVFDPQQTRCLSEFA 2851 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARGRGAVG 284 RAQ T + AAW +LL RYSGQA G G Sbjct: 2852 RAQRVTVNTLVQAAWLLLLQRYSGQATVCFGATVAG 2887 >ref|ZP_08494735.1| amino acid adenylation domain protein [Microcoleus vaginatus FGP-2] gb|EGK84893.1| amino acid adenylation domain protein [Microcoleus vaginatus FGP-2] Length = 1919 Score = 221 bits (562), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 114/270 (42%), Positives = 162/270 (60%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWF +Q PG Y++ RLTG LD +L +L+ L RH +LRT F Sbjct: 46 PLSFAQQRLWFFEQLTPGNFTYHILAGVRLTGTLDARSLDRSLNELVKRHEVLRTAFKTI 105 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 +G P Q +++ +DLR LP +R + ++ + A A FDL QA L +L+ L Sbjct: 106 NGQPVQAIASKLELKILEIDLRSLPETERSREVERLIAAEAKLAFDLSQAPLLRAKLLQL 165 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 VL++ HHI+SDAWS + I++LA Y+ + LP L +QYAD+A WQRQ Sbjct: 166 SASNWVLLLSTHHIISDAWSMGIFIQELATFYQAFCTGKPSPLPELSVQYADFASWQRQW 225 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 +QG L +L YW LG S L+LPTDRPR A Q+FRGAVH FT+ A+A+++ + Sbjct: 226 LQGEVLETQLAYWKKQLGGNLSVLNLPTDRPRSAVQTFRGAVHKFTIPKAIAEEIAQLSQ 285 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + T F+ L+AA++ LL RY+GQ D G Sbjct: 286 REKATLFMTLLAAFKTLLYRYTGQEDILVG 315 Score = 166 bits (420), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 103/270 (38%), Positives = 145/270 (53%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL Q +PG AYN+ A RL GAL+ A L + RH LRT F Sbjct: 1128 PLSFAQQRLWFLDQLQPGNPAYNIPAAVRLKGALNVAVLEQTFQEIIKRHEALRTTFKSV 1187 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 +G P Q + F L ++LR+L +RE A FDL + L V L+ L Sbjct: 1188 EGRPAQVIISSFNFTLPIVNLRELSQAEREAEAMRLAAEEARQPFDLTKWPLLRVTLLHL 1247 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 E++L++ +HHIV+D WS +++R++A Y + LP L +QYADYA WQ Sbjct: 1248 DDTEYLLLLTVHHIVADGWSMGVLVREVAALYEAFGSGKPSPLPELSVQYADYAVWQTNW 1307 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 +QG L +L W LG + L LP +PR A S + + F LD +++ + A R Sbjct: 1308 LQGEVLEAKLADWKQQLGQILPPLQLPAKQPRSAVSSNQAEIQEFQLDWQVSEALNALSR 1367 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 Q+ T F+ L+AA Q LL RY+ Q D G Sbjct: 1368 QQNVTLFMTLLAALQTLLYRYTNQEDIVVG 1397 >ref|YP_631823.1| non-ribosomal peptide synthetase [Myxococcus xanthus DK 1622] gb|ABF87402.1| non-ribosomal peptide synthetase [Myxococcus xanthus DK 1622] Length = 11939 Score = 220 bits (561), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 127/270 (47%), Positives = 164/270 (60%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL Q EP T YN+ + RL+GAL+ AL + DAL RH LRT F Sbjct: 10637 PLSFAQQRLWFLAQLEPDSTVYNVPASVRLSGALNVPALKQSFDALVHRHEALRTTFRTE 10696 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 G P Q P +L +DLR LP QRE+ Q Q A+ FDL L + L+AL Sbjct: 10697 GGSPVQVIDPRGGARLDIVDLRSLPAAQREEEAQRIAQEASQRPFDLESGPLLRLALLAL 10756 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 Q+HVLV+ MHHIVSD WS L++R+L E Y + + LP LP+QYADYA WQR+ Sbjct: 10757 SEQDHVLVLVMHHIVSDGWSMGLLVRELTEFYASFSQGQPSHLPELPLQYADYAVWQREW 10816 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 +QG L +L YW L L+LPTDRPRPA QS GA F+L L++ + A R Sbjct: 10817 LQGDVLDAQLGYWKQRLDGAPRLLELPTDRPRPAVQSLEGAYVPFSLGRELSEAVHALAR 10876 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + TPF+ L+AA+Q +L+RYSGQ D + G Sbjct: 10877 REGVTPFMVLLAAFQAVLARYSGQDDVSVG 10906 Score = 214 bits (546), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 120/271 (44%), Positives = 161/271 (59%) Query: 9 APLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE 68 APLS++QQ+LWFL Q +P T+YNL R+TGALD AL+ + +AL RH LRT F Sbjct: 1098 APLSFAQQRLWFLAQLDPANTSYNLWAPVRVTGALDVGALARSFEALVRRHEALRTTFRA 1157 Query: 69 TDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 G P Q V L +DL LP +RE + +A F L Q L L+ Sbjct: 1158 EGGSPVQVISAETQVPLEVVDLSVLPEGEREASAKARTEAEVGRPFQLEQGPLLRTVLLK 1217 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQ 188 L QEHVLV+ MHHIVSD WS +++R++A Y + AQLP L +QYAD+A WQR Sbjct: 1218 LSEQEHVLVLVMHHIVSDYWSMGILVREVAALYEALSQGRPAQLPELSVQYADFAMWQRD 1277 Query: 189 RVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 ++G L +L YW L +L+LPTD+PRPA Q+FRGA AL +++++ Sbjct: 1278 WLKGQVLESQLAYWRKQLAGAPRALELPTDKPRPATQTFRGANLHVLWPKALWREVESLG 1337 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 R + TPF+ L+AA+Q +LSRYSGQ D + G Sbjct: 1338 RREGVTPFMVLLAAFQTVLSRYSGQDDVSVG 1368 Score = 214 bits (544), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 117/270 (43%), Positives = 157/270 (58%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL Q EPG ++YN+ A LTG + AL A AL RH LRT F + Sbjct: 4275 PLSFAQQRLWFLDQLEPGSSSYNIPIAVTLTGTVQVDALEQAFKALVLRHESLRTTFQSS 4334 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 G P Q VQL +DLR L R +Q + AAH F+L + L L+ L Sbjct: 4335 GGEPAQVIAEESEVQLRVVDLRDLSEADRAPEVQRLISQEAAHPFNLARGPLLRTVLLKL 4394 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 QEHVLV+ MHHIVSD WS +++R++A Y + + LP LP+QYADYA WQR+ Sbjct: 4395 SEQEHVLVLVMHHIVSDGWSMGVLVREVAALYEACSQGLSSPLPELPLQYADYAVWQREW 4454 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 +QG L +L +W L + +L+LPTD+PRPA Q+F GA L + ++ Sbjct: 4455 LQGEVLESQLAWWKGQLQGASQALELPTDKPRPAVQTFHGASRDVQWPRDLWESVKVLAH 4514 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + TPF+ L+AA+Q +LSRYSGQ D G Sbjct: 4515 REGATPFMVLLAAFQTVLSRYSGQDDLCVG 4544 Score = 194 bits (492), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 111/270 (41%), Positives = 153/270 (56%), Gaps = 2/270 (0%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL+Q PG YN+ +++G LD AAL + DAL RH LRT F Sbjct: 5341 PLSFAQQRLWFLEQLAPGSVFYNVPAVVKVSGPLDVAALERSFDALVRRHESLRTTFHAD 5400 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 G P Q P V DL LP EQ Q A FDL + L L+ L Sbjct: 5401 GGTPVQVIAPVGQVVFTVEDLSGLP--DAEQEAQRRADVEALRPFDLAKGPLLRTMLLRL 5458 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 G +EH+LV+ MHHIVSD WS +++R++A Y + + LP L +QY DYA WQR+ Sbjct: 5459 GEREHLLVLMMHHIVSDGWSMGVLVREVAALYEAFSQGRPSPLPELAVQYPDYAVWQREW 5518 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 ++G L +L YW L ++L+LPTD+ RPA Q++ G + AL + M+A R Sbjct: 5519 LKGEVLEAQLGYWKQRLEGAPAALELPTDKARPAVQTYGGVLRHEVWPKALWRDMEALGR 5578 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + TPF+ L+AA+Q +LS+Y+GQ D G Sbjct: 5579 REGATPFMVLLAAYQWVLSKYAGQEDVCVG 5608 Score = 192 bits (487), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 117/280 (41%), Positives = 156/280 (55%), Gaps = 10/280 (3%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL+Q EPG YN+ A RL+GAL AL AL L RH +LRT F Sbjct: 2157 PLSFAQQRLWFLEQLEPGSPVYNIPLAIRLSGALRVDALERALRELVRRHEVLRTTFRSE 2216 Query: 70 DGLPYQ----QAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVR 125 G P Q QA PV +DL L + E + L+ + FDL L R Sbjct: 2217 GGTPVQIVSHQAENALPV----VDLSSLSSEAAEAEVDRLLREESLRGFDLPSGPLLRTR 2272 Query: 126 LIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQ-AQLPALPMQYADYAH 184 L+ EHVL+ MHHIVSD WS +++R+LA Y A R+GQ + LP L +QY D++ Sbjct: 2273 LLKRSEAEHVLLANMHHIVSDGWSMGVIVRELAALY-GAFREGQPSPLPELDVQYGDFSA 2331 Query: 185 WQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQM 244 WQR ++ L +L +W L L +PTDRP PA Q+FRGA ++ AL+ + Sbjct: 2332 WQRAWLESGALQRQLDWWRQQLEGAPHVLSIPTDRPLPAVQTFRGANLPVSIPPALSSGV 2391 Query: 245 QAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARGRGAVG 284 +A + TPF+ L+A +QVLL+RYSGQ D G G Sbjct: 2392 KALAQRHGATPFMVLLAGFQVLLARYSGQDDLVVGTPVAG 2431 Score = 189 bits (480), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 114/284 (40%), Positives = 158/284 (55%), Gaps = 16/284 (5%) Query: 4 PPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILR 63 P PLS++QQ+LWFL Q +PG YN++ +LTG LD AL + + L RH LR Sbjct: 3211 PRARELPLSFAQQRLWFLDQLQPGSAFYNVSAVVKLTGPLDPIALEWSFEELVRRHESLR 3270 Query: 64 TRFAETDGLPYQQAVPPFPVQLAWLDLRQLPPQQRE---QRLQEELQAAAAHVFDLGQAG 120 T F DG P Q + A + L L +R+ +RL EE A FDL + Sbjct: 3271 TTFRAKDGTPVQVISAEPTLAFAVVSLEALDDTERDAAAKRLAEE---EAQRPFDLKKGP 3327 Query: 121 QLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYA 180 L L+ L +EHVLV+ MHHIVSD WS +++R+++ Y + ++ LP LP+QY Sbjct: 3328 LLRATLLQLREREHVLVLVMHHIVSDEWSMGILVREVSALYEPLSQGQRSSLPDLPLQYG 3387 Query: 181 DYAHWQRQRVQGAWLADE-----LRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFT 235 DYA WQ + WLAD+ L YW L S+L LPTD+PRP Q+FRG++ Sbjct: 3388 DYAVWQHE-----WLADDVLEAQLGYWRQQLAGSPSALALPTDKPRPVMQTFRGSMQEAL 3442 Query: 236 LDSALAQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 S L ++A + + TPF+ L+AA+Q +LSRYS Q D + G Sbjct: 3443 WPSELWAAVKALGQREGATPFMVLLAAFQTVLSRYSDQDDVSVG 3486 Score = 187 bits (475), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 107/273 (39%), Positives = 156/273 (57%), Gaps = 6/273 (2%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL Q +P YN+ A +L+GALD AAL + +L RH LRT F Sbjct: 9578 PLSFAQQRLWFLHQLDPDSAFYNVPVAVKLSGALDVAALERSFHSLVLRHEALRTTFRSE 9637 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 G+P Q P L ++DL L ++ +Q + F+L L L+ Sbjct: 9638 AGVPTQVISPAGRGALEFVDLSALQGSEKTLEVQRRTELQTLRPFNLETGPLLRATLLKE 9697 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLA---EAYRQARRDGQAQLPALPMQYADYAHWQ 186 G + HVLV+ MHHIVSD WS +++R+L EAY Q R ++ L L +QYADYA WQ Sbjct: 9698 GEEAHVLVLVMHHIVSDGWSMGVLVRELVALYEAYSQGR---ESPLAELEVQYADYAVWQ 9754 Query: 187 RQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQA 246 R ++G L ++L YW L ++L+LPTD+ RPA Q++RG L + ++ Sbjct: 9755 RGWLKGEVLEEQLGYWRKQLAGAPAALELPTDKARPAVQTYRGDTRGLEWPKELWEGVKG 9814 Query: 247 FCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + ++ TPF+ L+AA+QV+LSRY+ Q D + G Sbjct: 9815 LGQRENATPFMVLLAAFQVVLSRYARQDDVSVG 9847 Score = 184 bits (466), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 114/277 (41%), Positives = 154/277 (55%), Gaps = 14/277 (5%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL Q EPG YN+ A RLTG LD AAL + D L RH LRT F Sbjct: 8519 PLSFAQQRLWFLDQLEPGSAFYNVPVAVRLTGVLDVAALRRSFDELVRRHESLRTTFRAQ 8578 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQR----EQRLQEELQAAAAHVFDLGQAGQLDVR 125 DG+P Q +L L R P +RL E+ A F+L L Sbjct: 8579 DGMPVQIVSDTASNRLEVLA-RGTPDDGEGGLETKRLAEQ---EALRPFNLETGPLLRAT 8634 Query: 126 LIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLA---EAYRQARRDGQAQLPALPMQYADY 182 L+ G + HVLV+ MHHIVSD WS +++R+L EAY Q R ++ L L +QYADY Sbjct: 8635 LLKEGEEAHVLVLVMHHIVSDGWSMGVLVRELVALYEAYSQGR---ESPLAELEVQYADY 8691 Query: 183 AHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQ 242 A WQR ++G L ++L YW L ++L+LPTD+ RPA Q++RG L + Sbjct: 8692 AVWQRGWLKGEVLEEQLGYWRKQLAGAPAALELPTDKARPAVQTYRGDTRGLEWPKGLWE 8751 Query: 243 QMQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 ++ + + TPF+ L+AA+QV+LSRY+ Q D G Sbjct: 8752 GVKGLAQRESATPFMVLLAAFQVVLSRYARQEDVCVG 8788 Score = 183 bits (465), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 109/274 (39%), Positives = 155/274 (56%), Gaps = 9/274 (3%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 PLS++QQ+LWFL Q EPG YN+ +LTG L AL A+ L RH LRT F + Sbjct: 6399 PLSFAQQRLWFLDQLEPGSPFYNVPSVVKLTGRLQTTALEASFSELVRRHESLRTTFRVS 6458 Query: 70 DGLPYQQAVPPFPVQ-LAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 G P Q + P+Q LD +L +RE R++ ++ F+L L L+ Sbjct: 6459 GGEPVQ-VIATDPLQPFQQLDFSELE-TERESRVRIWIEEEIQRPFNLETGPLLRATLLK 6516 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLA---EAYRQARRDGQAQLPALPMQYADYAHW 185 G + HVLV+ MHHIVSD WS +++R+L EAY Q R ++ L L +QYADYA W Sbjct: 6517 EGEEAHVLVLVMHHIVSDGWSMGVLVRELVALYEAYSQGR---ESPLAELEVQYADYAVW 6573 Query: 186 QRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQ 245 QR ++G L ++L YW L ++L+LPTD+ RPA Q++RG L + ++ Sbjct: 6574 QRGWLKGEVLEEQLGYWRKQLAGAPAALELPTDKARPAVQTYRGDTRGLEWPKGLWEGVK 6633 Query: 246 AFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + + TPF+ L+AA+QV+LSRY+ Q D G Sbjct: 6634 GLAQRESATPFMVLLAAFQVVLSRYARQEDVCVG 6667 Score = 176 bits (446), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 103/270 (38%), Positives = 146/270 (54%) Query: 10 PLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAET 69 P S++QQ+LW L Q E G +YN+ R+ G L L + L RH LRT F+ Sbjct: 7460 PPSFAQQRLWLLDQMEQGSASYNVPAVLRVEGPLQAEVLERSFVELVRRHESLRTTFSTR 7519 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 DG P Q + + L R + ++ A FDL + L V L+ L Sbjct: 7520 DGKPVQIIAAEPVLAFRSMGLESSAEAVRTAEVARLVEQEAHQRFDLERGPLLRVTLLKL 7579 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 QEHVL++ HHIVSD WS +++RD+ Y + + LP LP+QY DYA WQR+ Sbjct: 7580 AEQEHVLILVTHHIVSDGWSMGVLVRDVTALYEAFLQGRPSLLPELPVQYPDYAVWQREW 7639 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 ++G L +L YW L SL+LPTD+PRPA QSFRG + AL ++++A + Sbjct: 7640 LKGEVLESQLAYWKRQLKGAPQSLELPTDKPRPAAQSFRGGHLDQSWPLALWERVKALAQ 7699 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + TPF+ L+AA+QV+L+RY+ Q D G Sbjct: 7700 REGATPFMVLLAAFQVVLARYARQDDVCVG 7729 Score = 144 bits (362), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 99/283 (34%), Positives = 150/283 (53%), Gaps = 9/283 (3%) Query: 1 MSRPPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHA 60 + + P PL++SQQ++WFL Q PGL AY+L L+G LD A L + + RH Sbjct: 24 LEKKPRPALPLTFSQQRVWFLVQRAPGLPAYHLPLVLELSGRLDEAVLERSFQEVARRHE 83 Query: 61 ILRTRFAETDGLPYQ----QAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDL 116 LRT F E G P Q QA PF V+ L +P RE +++ +Q FDL Sbjct: 84 SLRTHFGEVSGTPVQFVDPQARLPFTVE----GLEDVPEAAREAAVRQRIQLELETPFDL 139 Query: 117 GQAGQLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALP 176 + L+ + P+ HVL++ +HH++SD S ++ ++ Y + + LP LP Sbjct: 140 SRGPLARGVLLRVAPERHVLLVVVHHLISDHESMGVLTHEMVALYDAFAQGQPSPLPVLP 199 Query: 177 MQYADYAHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTL 236 +QY DYA WQR +++G L L +W L L+L TDRPR + + R A L Sbjct: 200 LQYGDYASWQRGKLRGDALDAHLEFWRKRLEGAPHELELLTDRPRRS-ATGRAAQRRALL 258 Query: 237 DSALAQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + +++++ +A+ T F+A++A QVLLSRY+GQ D G Sbjct: 259 PVSWVERLESLAQAEGATLFMAVLAGLQVLLSRYTGQKDLLIG 301 >gb|AAX16327.1| PvdI(3) [Pseudomonas aeruginosa] Length = 3680 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 121/270 (44%), Positives = 168/270 (62%), Gaps = 2/270 (0%) Query: 11 LSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE-T 69 LSY+Q+++WFL Q +P AYNL A RL+G LDRAA AA +L RH LRT F + Sbjct: 52 LSYAQRRMWFLWQLDPQGAAYNLPMAVRLSGPLDRAAFEAAFASLVQRHETLRTVFPQRA 111 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 DG P Q A+ PV + + DL LP +RE L+E QA + FDL + L VRLI L Sbjct: 112 DGTPRQAALER-PVPIDFEDLSLLPEAERETCLRETAQAESLRPFDLCEGPLLRVRLIRL 170 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 G ++HVL++ +HHIVSD WS ++I + + Y+ + +A LP LP+QY+DYA WQR Sbjct: 171 GEEQHVLLLTLHHIVSDGWSMNVLIEEFSRFYKACMDNSEAGLPPLPIQYSDYALWQRSW 230 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 ++ +L YW + LG + L+LPTD PRPA+ S+RG + F +D AL Q ++A R Sbjct: 231 MEAGEQERQLAYWRERLGDQHPLLELPTDHPRPAQASYRGTRYEFEIDPALVQALRASAR 290 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 +Q T F+ L+ + +LL RYSGQ+D G Sbjct: 291 SQGLTLFMLLLGGFNILLQRYSGQSDLRVG 320 Score = 164 bits (416), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 105/271 (38%), Positives = 145/271 (53%), Gaps = 4/271 (1%) Query: 9 APLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE 68 +PLSY+QQ+ WFL Q EP AY++ A RL G LD AL + AL RH LRT F + Sbjct: 2615 SPLSYAQQRQWFLWQLEPDSAAYHIPAALRLCGELDVEALKRSFAALVERHEGLRTTFRQ 2674 Query: 69 TDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 G Q P+++ L R++EE++ FDL + L V L+ Sbjct: 2675 EGGETLQVVHDRLPLEIREQSLGVADEAALMARIEEEVRVP----FDLERGPLLRVLLLR 2730 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQ 188 L +E VLV+ +HHIVSD WS P+++ +L + Y R +L LP+QYADYA WQR Sbjct: 2731 LSAEEQVLVVTLHHIVSDGWSTPIMVEELMQFYAGYREGRAVELEPLPIQYADYALWQRS 2790 Query: 189 RVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 ++ +L YW LG L+LPTDRPRP+ QS G L L + ++ Sbjct: 2791 WMEAGERERQLAYWRQQLGGEQPVLELPTDRPRPSVQSPVGDSLQVELGEDLGRSLKQLA 2850 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + Q T F+ L+A++Q LL RYSGQ + G Sbjct: 2851 QQQGVTLFMLLLASFQTLLHRYSGQPEIRVG 2881 >gb|AAX16314.1| PvdI(3) [Pseudomonas aeruginosa] Length = 3680 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 121/270 (44%), Positives = 168/270 (62%), Gaps = 2/270 (0%) Query: 11 LSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE-T 69 LSY+Q+++WFL Q +P AYNL A RL+G LDRAA AA +L RH LRT F + Sbjct: 52 LSYAQRRMWFLWQLDPQGAAYNLPMAVRLSGPLDRAAFEAAFASLVQRHETLRTVFPQRA 111 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 DG P Q A+ PV + + DL LP +RE L+E QA + FDL + L VRLI L Sbjct: 112 DGTPRQAALER-PVPIDFEDLSLLPEAERETCLRETAQAESLRPFDLCEGPLLRVRLIRL 170 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 G ++HVL++ +HHIVSD WS ++I + + Y+ + +A LP LP+QY+DYA WQR Sbjct: 171 GEEQHVLLLTLHHIVSDGWSMNVLIEEFSRFYKACMDNSEAGLPPLPIQYSDYALWQRSW 230 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 ++ +L YW + LG + L+LPTD PRPA+ S+RG + F +D AL Q ++A R Sbjct: 231 MEAGEQERQLAYWRERLGDQHPLLELPTDHPRPAQASYRGTRYEFEIDPALVQALRASAR 290 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 +Q T F+ L+ + +LL RYSGQ+D G Sbjct: 291 SQGLTLFMLLLGGFNILLQRYSGQSDLRVG 320 Score = 164 bits (415), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 105/271 (38%), Positives = 145/271 (53%), Gaps = 4/271 (1%) Query: 9 APLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE 68 +PLSY+QQ+ WFL Q EP AY++ A RL G LD AL + AL RH LRT F + Sbjct: 2615 SPLSYAQQRQWFLWQLEPDSAAYHIPAALRLCGELDVEALKRSFAALVERHEGLRTTFRQ 2674 Query: 69 TDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 G Q P+++ L R++EE++ FDL + L V L+ Sbjct: 2675 EGGETLQVVHDRLPLEIREQSLGVADEAALMARIEEEVRVP----FDLERGPLLRVLLLR 2730 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQ 188 L +E VLV+ +HHIVSD WS P+++ +L + Y R +L LP+QYADYA WQR Sbjct: 2731 LSAEEQVLVVTLHHIVSDGWSTPIMVEELMQFYAGYREGRAVELEPLPIQYADYALWQRS 2790 Query: 189 RVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 ++ +L YW LG L+LPTDRPRP+ QS G L L + ++ Sbjct: 2791 WMEAGERERQLVYWRQQLGGEQPVLELPTDRPRPSVQSPAGDSLQVELGEDLGRSLKQLA 2850 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + Q T F+ L+A++Q LL RYSGQ + G Sbjct: 2851 QQQGVTLFMLLLASFQTLLHRYSGQPEIRVG 2881 >ref|YP_002440486.1| PvdI(3) [Pseudomonas aeruginosa LESB58] emb|CAW27622.1| PvdI(3) [Pseudomonas aeruginosa LESB58] Length = 3680 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 121/270 (44%), Positives = 168/270 (62%), Gaps = 2/270 (0%) Query: 11 LSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE-T 69 LSY+Q+++WFL Q +P AYNL A RL+G LDRAA AA +L RH LRT F + Sbjct: 52 LSYAQRRMWFLWQLDPQGAAYNLPMAVRLSGPLDRAAFEAAFASLVQRHETLRTVFPQRA 111 Query: 70 DGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIAL 129 DG P Q A+ PV + + DL LP +RE L+E QA + FDL + L VRLI L Sbjct: 112 DGTPRQAALER-PVPIDFEDLSLLPEAERETCLRETAQAESLRPFDLCEGPLLRVRLIRL 170 Query: 130 GPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQR 189 G ++HVL++ +HHIVSD WS ++I + + Y+ + +A LP LP+QY+DYA WQR Sbjct: 171 GEEQHVLLLTLHHIVSDGWSMNVLIEEFSRFYKACMDNSEAGLPPLPIQYSDYALWQRSW 230 Query: 190 VQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFCR 249 ++ +L YW + LG + L+LPTD PRPA+ S+RG + F +D AL Q ++A R Sbjct: 231 MEAGEQERQLAYWRERLGDQHPLLELPTDHPRPAQASYRGTRYEFEIDPALVQALRASAR 290 Query: 250 AQHCTPFVALMAAWQVLLSRYSGQADFARG 279 +Q T F+ L+ + +LL RYSGQ+D G Sbjct: 291 SQGLTLFMLLLGGFNILLQRYSGQSDLRVG 320 Score = 164 bits (415), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 105/271 (38%), Positives = 145/271 (53%), Gaps = 4/271 (1%) Query: 9 APLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILRTRFAE 68 +PLSY+QQ+ WFL Q EP AY++ A RL G LD AL + AL RH LRT F + Sbjct: 2615 SPLSYAQQRQWFLWQLEPDSAAYHIPAALRLCGELDVEALKRSFAALVERHEGLRTTFRQ 2674 Query: 69 TDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLDVRLIA 128 G Q P+++ L R++EE++ FDL + L V L+ Sbjct: 2675 EGGETLQVVHDRLPLEIREQSLGVADEAALMARIEEEVRVP----FDLERGPLLRVLLLR 2730 Query: 129 LGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYAHWQRQ 188 L +E VLV+ +HHIVSD WS P+++ +L + Y R +L LP+QYADYA WQR Sbjct: 2731 LSAEEQVLVVTLHHIVSDGWSTPIMVEELMQFYAGYREGRAVELEPLPIQYADYALWQRS 2790 Query: 189 RVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQMQAFC 248 ++ +L YW LG L+LPTDRPRP+ QS G L L + ++ Sbjct: 2791 WMEAGERERQLVYWRQQLGGEQPVLELPTDRPRPSVQSPAGDSLQVELGEDLGRSLKQLA 2850 Query: 249 RAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 + Q T F+ L+A++Q LL RYSGQ + G Sbjct: 2851 QQQGVTLFMLLLASFQTLLHRYSGQPEIRVG 2881 >ref|ZP_05029367.1| amino acid adenylation domain protein [Microcoleus chthonoplastes PCC 7420] gb|EDX72563.1| amino acid adenylation domain protein [Microcoleus chthonoplastes PCC 7420] Length = 1604 Score = 218 bits (554), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 120/276 (43%), Positives = 157/276 (56%), Gaps = 1/276 (0%) Query: 4 PPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHAILR 63 P ++ PLS+ Q++LWFL Q E G TAYN R+TGALD +A+ A + RH +LR Sbjct: 73 PRNQPLPLSFGQERLWFLDQLE-GSTAYNEHGGIRITGALDVSAIQRAFAEVLRRHEVLR 131 Query: 64 TRFAETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAGQLD 123 T F DG+P Q P +L LD + L +RE RL + Q A DL + Sbjct: 132 TTFPLVDGMPQQAIAPEATAELTQLDWQHLSASERESRLSDYAQQQAQMRVDLAAGPLVY 191 Query: 124 VRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYADYA 183 LI L P E VL+I MHHI+ D WS + I++L+ Y+ + +QLP L +QYADYA Sbjct: 192 ATLIHLAPDEWVLLIVMHHIICDYWSIGIFIQELSALYQSFSQQKPSQLPELVIQYADYA 251 Query: 184 HWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSALAQQ 243 HWQR R+ G WL +L YW + L V S L LPTDRPRP+ Q +RG F +D L QQ Sbjct: 252 HWQRHRLNGEWLESQLSYWKEQLANVPSLLKLPTDRPRPSVQRYRGEAQTFIIDPWLTQQ 311 Query: 244 MQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 +Q + T F+ L+AA+ LL RYS Q D G Sbjct: 312 LQELSQRCGTTLFMTLLAAFSTLLYRYSAQEDILIG 347 >ref|YP_001520888.1| nonribosomal protein synthetase [Acaryochloris marina MBIC11017] gb|ABW31356.1| nonribosomal protein synthetase [Acaryochloris marina MBIC11017] Length = 1573 Score = 215 bits (547), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 125/279 (44%), Positives = 162/279 (58%), Gaps = 2/279 (0%) Query: 1 MSRPPHEHAPLSYSQQQLWFLQQYEPGLTAYNLTRAFRLTGALDRAALSAALDALQARHA 60 ++RP EH LS++QQ+LWFL Q EP YN+ A RLTG LD AL + +A+ RH Sbjct: 81 IARP--EHVSLSFAQQRLWFLDQMEPNSPLYNIPAAARLTGTLDAIALDQSFNAIVQRHE 138 Query: 61 ILRTRFAETDGLPYQQAVPPFPVQLAWLDLRQLPPQQREQRLQEELQAAAAHVFDLGQAG 120 LRT F DG P Q VP V L +DL L ++E R+ + Q A FDL QA Sbjct: 139 SLRTAFQAVDGQPVQMIVPELTVPLQRVDLSTLDKAEQEVRVLQLAQQEAQQPFDLTQAP 198 Query: 121 QLDVRLIALGPQEHVLVIGMHHIVSDAWSNPLVIRDLAEAYRQARRDGQAQLPALPMQYA 180 L V LI L EHV+++ MHHI+SDAWS +++++L Y + L L +QYA Sbjct: 199 LLRVTLIRLTDTEHVVLLTMHHIISDAWSMDILLQELTALYGAFSAGQPSPLSELSIQYA 258 Query: 181 DYAHWQRQRVQGAWLADELRYWDDYLGPVNSSLDLPTDRPRPARQSFRGAVHAFTLDSAL 240 D A WQRQ +QG L L YW LG L LP+DRPRP QSFRGA H FTL + L Sbjct: 259 DLAVWQRQWLQGEVLERHLSYWHQQLGGNLPILQLPSDRPRPRVQSFRGAKHTFTLSAEL 318 Query: 241 AQQMQAFCRAQHCTPFVALMAAWQVLLSRYSGQADFARG 279 ++A + T F+ L+A+++VLL RY+GQAD G Sbjct: 319 TAALKALSQQAGVTLFMTLLASFKVLLHRYTGQADLLVG 357