BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0060.p (466 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776688.1| 3-isopropylmalate dehydratase large subunit ... 961 0.0 ref|YP_001353862.1| 3-isopropylmalate dehydratase large subunit ... 883 0.0 ref|YP_004752521.1| 3-isopropylmalate dehydratase large subunit ... 882 0.0 ref|YP_001099519.1| isopropylmalate isomerase large subunit [Her... 872 0.0 ref|ZP_08272573.1| 3-isopropylmalate dehydratase large subunit [... 847 0.0 emb|CCA84366.1| 3-isopropylmalate isomerase, subunit with leuD [... 786 0.0 ref|YP_002981775.1| isopropylmalate isomerase large subunit [Ral... 784 0.0 ref|ZP_03569999.1| 3-isopropylmalate dehydratase, large subunit ... 784 0.0 ref|NP_520111.1| isopropylmalate isomerase large subunit [Ralsto... 784 0.0 gb|AEG68748.1| 3-isopropylmalate dehydratase large subunit prote... 784 0.0 >ref|YP_003776688.1| 3-isopropylmalate dehydratase large subunit [Herbaspirillum seropedicae SmR1] gb|ADJ64780.1| 3-isopropylmalate dehydratase (large subunit) protein [Herbaspirillum seropedicae SmR1] Length = 466 Score = 961 bits (2485), Expect = 0.0, Method: Compositional matrix adjust. Identities = 465/466 (99%), Positives = 466/466 (100%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV Sbjct: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTTDRA+GIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRAHGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA Sbjct: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL Sbjct: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV Sbjct: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK Sbjct: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 >ref|YP_001353862.1| 3-isopropylmalate dehydratase large subunit [Janthinobacterium sp. Marseille] sp|A6T015.1|LEUC_JANMA RecName: Full=3-isopropylmalate dehydratase large subunit; AltName: Full=Alpha-IPM isomerase; Short=IPMI; AltName: Full=Isopropylmalate isomerase gb|ABR88947.1| 3-isopropylmalate dehydratase large subunit [Janthinobacterium sp. Marseille] Length = 468 Score = 883 bits (2281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/466 (90%), Positives = 439/466 (94%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M +TLYDKLW+SHVV T DDGT +LYIDRHLLHEVTSPQAFEGLKLAGR+PWR SANLMV Sbjct: 1 MAQTLYDKLWQSHVVETGDDGTTVLYIDRHLLHEVTSPQAFEGLKLAGRRPWRVSANLMV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTTDRANGIADP SRLQVETLDGNA EY LTYF M DKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRANGIADPTSRLQVETLDGNAHEYGLTYFSMRDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF LAHGIGTSEVEHVLATQTLLA+KSKAMLVQVDGALP GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLLAQKSKAMLVQVDGALPDGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMT+CNMAIEAGARAGMVA DD T+ Sbjct: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTICNMAIEAGARAGMVAVDDITI 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 Y+KGRP SP GPHW+RAV YWR+LHSD GAKFD+VVTLNAAEIKPQV+WGTSPEMVVAV Sbjct: 241 NYVKGRPLSPVGPHWDRAVEYWRTLHSDAGAKFDLVVTLNAAEIKPQVSWGTSPEMVVAV 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 D RVPDPDKEKDPTKRDGMEKAL YMALKPNTPI DIRIDKVFIGSCTNSRIEDLR AA Sbjct: 301 DGRVPDPDKEKDPTKRDGMEKALIYMALKPNTPITDIRIDKVFIGSCTNSRIEDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGK+RASNVKLAMVVPGSGLVKEQAEREGLDKIF+ AGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKYRASNVKLAMVVPGSGLVKEQAEREGLDKIFKAAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGI GHFVDVR+L Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIEGHFVDVRAL 466 >ref|YP_004752521.1| 3-isopropylmalate dehydratase large subunit [Collimonas fungivorans Ter331] gb|AEK61698.1| 3-isopropylmalate dehydratase large subunit [Collimonas fungivorans Ter331] Length = 466 Score = 882 bits (2280), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/466 (92%), Positives = 446/466 (95%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 MLKTLYDKLWESHVVHTE DGTAILYIDRHLLHEVTSPQAFEGLKLAGR+PWR +ANLMV Sbjct: 1 MLKTLYDKLWESHVVHTEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRKPWRQAANLMV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTT RANGIADPISRLQVETLD NAK Y LTYFGMND RQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTGRANGIADPISRLQVETLDANAKSYDLTYFGMNDHRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF LAHGIGTSEVEHVLATQTLL +KSK+MLVQVDGA+PAGVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLLTKKSKSMLVQVDGAIPAGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLAVIG+IGTAGGTGYAIEFAGS IR+LSMEGRMTVCNMAIEAGARAGM+A DDTTL Sbjct: 181 KDIVLAVIGRIGTAGGTGYAIEFAGSAIRALSMEGRMTVCNMAIEAGARAGMIAVDDTTL 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 Y+KGRPFSP+GPHWERAV+YWR+LHSD GAKFDMVVTL AAEIKPQVTWGTSPEMVVAV Sbjct: 241 NYVKGRPFSPAGPHWERAVTYWRTLHSDQGAKFDMVVTLGAAEIKPQVTWGTSPEMVVAV 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 D RVPDPDKEKD TKRDGMEKALAYMALKPNT IEDIRIDKVFIGSCTNSRIEDLR AA Sbjct: 301 DGRVPDPDKEKDATKRDGMEKALAYMALKPNTAIEDIRIDKVFIGSCTNSRIEDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIF+DAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFKDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVD+RSL Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDIRSL 466 >ref|YP_001099519.1| isopropylmalate isomerase large subunit [Herminiimonas arsenicoxydans] sp|A4G4F5.1|LEUC_HERAR RecName: Full=3-isopropylmalate dehydratase large subunit; AltName: Full=Alpha-IPM isomerase; Short=IPMI; AltName: Full=Isopropylmalate isomerase emb|CAL61392.1| 3-isopropylmalate dehydratase large subunit (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) [Herminiimonas arsenicoxydans] Length = 466 Score = 872 bits (2254), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/466 (89%), Positives = 437/466 (93%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M +TLYDKLW+SHVV T DDGT +LYIDRHLLHEVTSPQAFEGLKLAGR+PWR SANLMV Sbjct: 1 MAQTLYDKLWQSHVVDTGDDGTTVLYIDRHLLHEVTSPQAFEGLKLAGRRPWRVSANLMV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTTDR+ GIADP SRLQVETLD NA EY LTYF M DKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRSEGIADPTSRLQVETLDHNAHEYGLTYFSMRDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF ALAHGIGTSEVEHVLATQTLLA+KSKAMLVQVDGALP GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAQKSKAMLVQVDGALPVGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLA+IGKIGTAGGTGYAIEFAGSTIRSLSMEGRMT+CNMAIEAGARAGMVA D+TT+ Sbjct: 181 KDIVLAIIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTICNMAIEAGARAGMVAVDETTI 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 Y+KGRP SP GPHW+RAV YWR+LHSD GAKFD+VVTLNAAE+KPQV+WGTSPEMVV+V Sbjct: 241 NYVKGRPLSPVGPHWDRAVEYWRTLHSDVGAKFDLVVTLNAAEVKPQVSWGTSPEMVVSV 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 D RVPDPDKEKD TKRDGMEKAL YM LKPNTPI DIRIDKVFIGSCTNSRI+DLR AA Sbjct: 301 DGRVPDPDKEKDATKRDGMEKALVYMGLKPNTPITDIRIDKVFIGSCTNSRIQDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGK RASNVKLAMVVPGSGLVKEQAEREGLDKIF+DAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKHRASNVKLAMVVPGSGLVKEQAEREGLDKIFKDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGI GHFVDVR+L Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIEGHFVDVRAL 466 >ref|ZP_08272573.1| 3-isopropylmalate dehydratase large subunit [Oxalobacteraceae bacterium IMCC9480] gb|EGF33962.1| 3-isopropylmalate dehydratase large subunit [Oxalobacteraceae bacterium IMCC9480] Length = 466 Score = 847 bits (2187), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/466 (88%), Positives = 437/466 (93%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M +TLYDKLW+SHVV T DGT ILYIDRHL+HEVTSPQAF+GLKLAGRQPWR SANL V Sbjct: 1 MAQTLYDKLWDSHVVDTASDGTTILYIDRHLVHEVTSPQAFDGLKLAGRQPWRLSANLAV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTTDRA GIADP SRLQVETLD NAK Y LTYF M DKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRAQGIADPTSRLQVETLDANAKTYGLTYFNMADKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF LAHGIGTSEVEHVLATQTLL +KS++MLVQ+DGALP GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLLTKKSRSMLVQIDGALPRGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLAVIG+IGTAGG GYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGM+A DDTT+ Sbjct: 181 KDIVLAVIGQIGTAGGNGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 +Y+KGRPFSP GPHWERAVS+WR+LHSD GA+FD+VV L+A++++PQVTWGTSPEMVVA+ Sbjct: 241 DYVKGRPFSPVGPHWERAVSWWRTLHSDAGARFDLVVRLDASQVRPQVTWGTSPEMVVAI 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 D RVPDPDKEKDPTKRD MEKALAYMALKPNT I DIRIDKVFIGSCTNSRIEDLR AA Sbjct: 301 DDRVPDPDKEKDPTKRDSMEKALAYMALKPNTAIADIRIDKVFIGSCTNSRIEDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGKFRASNV+LAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKFRASNVRLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVR+L Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRTL 466 >emb|CCA84366.1| 3-isopropylmalate isomerase, subunit with leuD [Ralstonia syzygii R24] Length = 469 Score = 786 bits (2029), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/468 (81%), Positives = 417/468 (89%), Gaps = 2/468 (0%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M KTLYDKLW+ HVVHTE+DGT +LYIDR LLHEVTSPQAFEGL+LA R WR SANL V Sbjct: 1 MAKTLYDKLWDDHVVHTEEDGTTVLYIDRQLLHEVTSPQAFEGLRLAHRPVWRISANLAV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 +DHNVPTTDR++GIADP+S+LQV+TLD N Y +T F MNDKRQGIVHVIGPEQGATLP Sbjct: 61 SDHNVPTTDRSHGIADPVSKLQVDTLDANCDSYGITQFKMNDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF ALAHGIGTSEVEHVLATQTLLA+KSK MLV+V+G LP G TA Sbjct: 121 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAKKSKNMLVKVEGTLPRGCTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLA+IGKIGTAGGTGYA+EF GS IR+LSMEGRMTVCNMAIEAGARAGMV DD TL Sbjct: 181 KDIVLAIIGKIGTAGGTGYAMEFGGSAIRALSMEGRMTVCNMAIEAGARAGMVGVDDITL 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 EY+KGRPF+P G WE+AV+YWR+LHSD GA+FD VV L A EI+PQV+WGTSPEMVV++ Sbjct: 241 EYIKGRPFAPQGVEWEQAVAYWRTLHSDEGARFDHVVELRAEEIRPQVSWGTSPEMVVSI 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 + RVPDPDKEKDP KR+ ME+AL YMAL+PN I DIRIDKVFIGSCTNSRIED+R AA Sbjct: 301 EDRVPDPDKEKDPVKRNAMERALEYMALQPNVAISDIRIDKVFIGSCTNSRIEDMRAAAW 360 Query: 361 VVR--GKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADR 418 VV+ GK ASNVKLAMVVPGSGLVKEQAEREGLDKIF+ AGFEWREPGCSMCLAMNADR Sbjct: 361 VVQKLGKRIASNVKLAMVVPGSGLVKEQAEREGLDKIFKAAGFEWREPGCSMCLAMNADR 420 Query: 419 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAA + GHFVDVR L Sbjct: 421 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAALEGHFVDVRKL 468 >ref|YP_002981775.1| isopropylmalate isomerase large subunit [Ralstonia pickettii 12D] gb|ACS63103.1| 3-isopropylmalate dehydratase, large subunit [Ralstonia pickettii 12D] Length = 469 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/468 (81%), Positives = 414/468 (88%), Gaps = 2/468 (0%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M KTLYDKLW+ HVVHTE+DGT +LYIDR LLHEVTSPQAFEGLKLA R WR SANL V Sbjct: 1 MAKTLYDKLWDDHVVHTEEDGTTVLYIDRQLLHEVTSPQAFEGLKLAQRPVWRISANLAV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 +DHNVPTTDR++GIADP+S+LQV+TLD N Y +T F MNDKRQGIVHVIGPEQGATLP Sbjct: 61 SDHNVPTTDRSHGIADPVSKLQVDTLDANCDSYGITQFKMNDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF ALAHGIGTSEVEHVLATQTLLA+KSK MLV+V+G LP G TA Sbjct: 121 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAKKSKNMLVKVEGTLPRGCTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLA+IGKIGTAGGTGYA+EF GS IR+LSMEGRMTVCNMAIEAGARAGMVA DD TL Sbjct: 181 KDIVLAIIGKIGTAGGTGYAMEFGGSAIRALSMEGRMTVCNMAIEAGARAGMVAVDDVTL 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 EY+KGRPF+P G WE+AV+YWR+LHSD GA FD VV L A EI+PQV+WGTSPEMVV++ Sbjct: 241 EYIKGRPFAPQGVEWEQAVAYWRTLHSDEGAHFDRVVELRAEEIRPQVSWGTSPEMVVSI 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 + RVPDPDKEKDP KR+ ME+AL YM L+PN I DI IDKVFIGSCTNSRIED+R AA Sbjct: 301 EDRVPDPDKEKDPNKRNAMERALEYMGLQPNVAISDINIDKVFIGSCTNSRIEDMRAAAW 360 Query: 361 VVR--GKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADR 418 VV+ GK A NVKLAMVVPGSGLVKEQAEREGLDKIF+ AGFEWREPGCSMCLAMNADR Sbjct: 361 VVQKLGKRIAPNVKLAMVVPGSGLVKEQAEREGLDKIFKSAGFEWREPGCSMCLAMNADR 420 Query: 419 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAA + GHFVDVR L Sbjct: 421 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAALEGHFVDVRKL 468 >ref|ZP_03569999.1| 3-isopropylmalate dehydratase, large subunit [Burkholderia multivorans CGD2M] ref|ZP_03576643.1| 3-isopropylmalate dehydratase, large subunit [Burkholderia multivorans CGD2] gb|EEE08220.1| 3-isopropylmalate dehydratase, large subunit [Burkholderia multivorans CGD2] gb|EEE15906.1| 3-isopropylmalate dehydratase, large subunit [Burkholderia multivorans CGD2M] Length = 469 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/468 (80%), Positives = 416/468 (88%), Gaps = 2/468 (0%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M +TLYDKLW SHVVHTE+DGTA+LYIDR LLHEVTSPQAFEGLK+A R WR SANL V Sbjct: 1 MAQTLYDKLWNSHVVHTEEDGTALLYIDRQLLHEVTSPQAFEGLKIAQRPVWRISANLAV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 +DHNVPTTDR++GIADP+S+LQV+TLD N + +T F MND RQGIVH+IGPEQGATLP Sbjct: 61 SDHNVPTTDRSHGIADPVSKLQVDTLDANCDAFGITQFKMNDVRQGIVHIIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMT+VCGDSHTSTHGAF ALAHGIGTSEVEHVLATQTLL +KSK MLV+V+GALP G TA Sbjct: 121 GMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLQKKSKNMLVKVEGALPRGCTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLA+IGKIGTAGGTGYAIEF GSTIR+LSMEGRMTVCNMAIEAGARAGMVA DDTT+ Sbjct: 181 KDIVLAIIGKIGTAGGTGYAIEFGGSTIRALSMEGRMTVCNMAIEAGARAGMVAVDDTTI 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 +YLKGRPF PSG W++AV YWR SD GA FD VV LNAAEI PQVTWGTSPEMV ++ Sbjct: 241 DYLKGRPFVPSGAEWDQAVEYWRQFKSDEGAHFDRVVELNAAEIVPQVTWGTSPEMVTSI 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 D RVPDP++EKDP KRD ME+ALAYMAL+PNTPIE I++DK+FIGSCTN+RIED+R AA Sbjct: 301 DGRVPDPEREKDPVKRDAMERALAYMALEPNTPIESIKVDKIFIGSCTNARIEDIRAAAY 360 Query: 361 VVRGKFR--ASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADR 418 VV+ R ASNV+LAMVVPGSGLVK QAEREGLDK+F DAGFEWREPGCSMCLAMNADR Sbjct: 361 VVKKLNRRVASNVRLAMVVPGSGLVKAQAEREGLDKVFTDAGFEWREPGCSMCLAMNADR 420 Query: 419 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAA I GHFVD+R L Sbjct: 421 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAIEGHFVDIRKL 468 >ref|NP_520111.1| isopropylmalate isomerase large subunit [Ralstonia solanacearum GMI1000] sp|Q8XXX3.1|LEUC_RALSO RecName: Full=3-isopropylmalate dehydratase large subunit; AltName: Full=Alpha-IPM isomerase; Short=IPMI; AltName: Full=Isopropylmalate isomerase emb|CAD15692.1| probable 3-isopropylmalate dehydratase large subunit (isopropylmalate isomerase) (alpha-ipm isomerase) (ipmi) protein [Ralstonia solanacearum GMI1000] Length = 469 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/468 (81%), Positives = 416/468 (88%), Gaps = 2/468 (0%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M KTLYDKLW+ HVVHTE+DGT +LYIDR LLHEVTSPQAFEGLKLA R WR SANL V Sbjct: 1 MAKTLYDKLWDDHVVHTEEDGTTVLYIDRQLLHEVTSPQAFEGLKLANRPVWRISANLAV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 +DHNVPTTDR++GIADP+S+LQV+TLD N + +T F M DKRQGIVHVIGPEQGATLP Sbjct: 61 SDHNVPTTDRSHGIADPVSKLQVDTLDANCDSFGITQFKMTDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF ALAHGIGTSEVEHVLATQTLLA+KSK MLV+V+G LP G TA Sbjct: 121 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAKKSKNMLVKVEGTLPRGCTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLA+IGKIGTAGGTGYA+EF GS IR+LSMEGRMTVCNMAIEAGARAGMV DD TL Sbjct: 181 KDIVLAIIGKIGTAGGTGYAMEFGGSAIRALSMEGRMTVCNMAIEAGARAGMVGVDDITL 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 EY+KGRPF+P G WE+AV+YWRSLHSD GA+FD VV L A EI+PQV+WGTSPEMVV++ Sbjct: 241 EYIKGRPFAPQGVEWEQAVAYWRSLHSDEGARFDHVVELRAEEIRPQVSWGTSPEMVVSI 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 + RVPDPDKEKDP KR+ ME+AL YMAL+PN I DIRIDKVFIGSCTNSRIED+R AA Sbjct: 301 EDRVPDPDKEKDPVKRNAMERALEYMALQPNVAIGDIRIDKVFIGSCTNSRIEDMRAAAW 360 Query: 361 VVR--GKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADR 418 VV+ GK ASNVKLAMVVPGSGLVKEQAEREGLDKIF+ AGFEWREPGCSMCLAMNADR Sbjct: 361 VVQKLGKRIASNVKLAMVVPGSGLVKEQAEREGLDKIFKAAGFEWREPGCSMCLAMNADR 420 Query: 419 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAA + GHFVDVR L Sbjct: 421 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAALEGHFVDVRKL 468 >gb|AEG68748.1| 3-isopropylmalate dehydratase large subunit protein [Ralstonia solanacearum Po82] Length = 469 Score = 784 bits (2024), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/468 (81%), Positives = 415/468 (88%), Gaps = 2/468 (0%) Query: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 M KTLYDKLW+ HVVHTE+DGT +LYIDR LLHEVTSPQAFEGLKLA R WR SANL V Sbjct: 1 MAKTLYDKLWDDHVVHTEEDGTTVLYIDRQLLHEVTSPQAFEGLKLAHRPVWRISANLAV 60 Query: 61 ADHNVPTTDRANGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 +DHNVPTTDR++GIADP+S+LQV+TLD N Y +T F M DKRQGIVHVIGPEQGATLP Sbjct: 61 SDHNVPTTDRSHGIADPVSKLQVDTLDANCDSYGITQFKMTDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 GMTVVCGDSHTSTHGAF ALAHGIGTSEVEHVLATQTLLA+KSK MLV+V+G LP G TA Sbjct: 121 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAKKSKNMLVKVEGTLPRGCTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 KDIVLA+IGKIGTAGGTGYA+EF GS IR+LSMEGRMTVCNMAIEAGARAGMV DD TL Sbjct: 181 KDIVLAIIGKIGTAGGTGYAMEFGGSAIRALSMEGRMTVCNMAIEAGARAGMVGVDDITL 240 Query: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 EY+KGRPF+P G WE+AV+YWRSLHSD GA FD VV L A EI+PQV+WGTSPEMVV++ Sbjct: 241 EYIKGRPFAPQGVEWEQAVAYWRSLHSDEGAHFDHVVELRAEEIRPQVSWGTSPEMVVSI 300 Query: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 + RVPDPDKEKDP KR+ ME+AL YMAL+PN I DIRIDKVFIGSCTNSRIED+R AA Sbjct: 301 EDRVPDPDKEKDPVKRNAMERALEYMALQPNVAISDIRIDKVFIGSCTNSRIEDMRAAAW 360 Query: 361 VVR--GKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADR 418 VV+ GK ASNVKLAMVVPGSGLVKEQAEREGLD+IF+ AGFEWREPGCSMCLAMNADR Sbjct: 361 VVQKLGKRIASNVKLAMVVPGSGLVKEQAEREGLDQIFKAAGFEWREPGCSMCLAMNADR 420 Query: 419 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAA + GHFVDVR L Sbjct: 421 LEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAALEGHFVDVRKL 468