BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0017.p (319 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776725.1| D-3-phosphoglycerate dehydrogenase [Herbaspi... 647 0.0 ref|YP_003409482.1| NAD-binding D-isomer specific 2-hydroxyacid ... 313 2e-83 ref|YP_003322014.1| D-isomer specific 2-hydroxyacid dehydrogenas... 296 2e-78 ref|NP_693741.1| dehydrogenase [Oceanobacillus iheyensis HTE831]... 233 2e-59 ref|YP_003991614.1| d-isomer specific 2-hydroxyacid dehydrogenas... 229 5e-58 ref|ZP_07931609.1| D-isomer specific 2-hydroxyacid dehydrogenase... 229 6e-58 ref|ZP_08599488.1| D-3-phosphoglycerate dehydrogenase [Fusobacte... 228 7e-58 ref|ZP_07930558.1| D-isomer specific 2-hydroxyacid dehydrogenase... 228 7e-58 ref|ZP_02419587.1| hypothetical protein ANACAC_02181 [Anaerostip... 226 5e-57 ref|YP_004820408.1| NAD-binding D-isomer specific 2-hydroxyacid ... 225 6e-57 >ref|YP_003776725.1| D-3-phosphoglycerate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64817.1| D-3-phosphoglycerate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 319 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/319 (99%), Positives = 319/319 (100%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF Sbjct: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY Sbjct: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 DRAVKAG+WHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF Sbjct: 121 DRAVKAGEWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 Query: 181 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD 240 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD Sbjct: 181 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD 240 Query: 241 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQNL 300 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAA+NL Sbjct: 241 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAKNL 300 Query: 301 IDWDRTGRPSYVVVQGKNK 319 IDWDRTGRPSYVVVQGKNK Sbjct: 301 IDWDRTGRPSYVVVQGKNK 319 >ref|YP_003409482.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein [Geodermatophilus obscurus DSM 43160] gb|ADB75111.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Geodermatophilus obscurus DSM 43160] Length = 322 Score = 313 bits (802), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 155/317 (48%), Positives = 215/317 (67%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 ++VL+TD D+ +D+E + AG E+ TA+CRT EVI A+ +LVQYAP+ A+V Sbjct: 6 LRVLVTDADYGVLDIEEQVLAAAGHELRTARCRTPAEVIDAARDADAVLVQYAPITAEVL 65 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 A P +R+ SRYG G D ++T A A GVWV N PDYG EVA HA+A+ L L+RN+ + Sbjct: 66 DALPRLRLVSRYGVGVDVVDTDAARARGVWVCNVPDYGTTEVALHAVAVLLALLRNLPEH 125 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 DR V AG+W + G + R LT+G++GLGRIG+ + F V+ +DP++ D + Sbjct: 126 DRQVHAGRWDHRLGGRLRRPDGLTLGVVGLGRIGRTTMAGAAPWFGAVVGHDPHLPDDAW 185 Query: 181 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD 240 PA VER+G ELF ++ V+LH PL +TR ++ A LL + A SYLVN+ARGGLV++D Sbjct: 186 PAGVERLGLAELFARSDAVTLHLPLTADTRGLVGADLLGRMPAGSYLVNTARGGLVQLDA 245 Query: 241 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQNL 300 +L ALE+G+L G LDV P EPP S ++ HPR LL+PH A++S+ A ELRRKAA N+ Sbjct: 246 VLQALEDGRLAGVGLDVFPTEPPPAGSPLLAHPRALLTPHVAWYSEEAEVELRRKAAGNV 305 Query: 301 IDWDRTGRPSYVVVQGK 317 + W RTGRP +VVV+G+ Sbjct: 306 VSWARTGRPDHVVVEGR 322 >ref|YP_003322014.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobaculum terrenum ATCC BAA-798] gb|ACZ41192.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobaculum terrenum ATCC BAA-798] Length = 324 Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 152/314 (48%), Positives = 212/314 (67%) Query: 2 KVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVFA 61 KVLITD ++PD+ E L +EAG +V AQCR EEVI A+ L+VQYAP+ + V Sbjct: 5 KVLITDAEYPDLSDEQRLLEEAGCQVSIAQCRLPEEVILAARDAFALMVQYAPITSDVIH 64 Query: 62 ARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVYD 121 A P +++ SR G G D+++ A GVWVAN PDYGV EVA+HA AM L L+R++ D Sbjct: 65 ALPNLKLISRAGVGVDSVDLDAAKEKGVWVANVPDYGVHEVASHAAAMILSLLRHVCFLD 124 Query: 122 RAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDFP 181 R V+ G WHY + G I R S LT+G++GLGRIG+ +A + ++F RVI YDPY+ +P Sbjct: 125 RKVREGVWHYLSTGEIHRISSLTLGVVGLGRIGRTLASMMLHVFGRVIGYDPYLPANAWP 184 Query: 182 AYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDDL 241 V+RV +LF +++VVSLH PL ET NM++ L L+ SYLVN+ARGGLV ++DL Sbjct: 185 EGVDRVDLRDLFMKSNVVSLHLPLTKETSNMVNREFLALMPVGSYLVNTARGGLVNMEDL 244 Query: 242 LAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQNLI 301 + L++G L GAALDVLP EPP I+ HP+++++PH A++S+ + +ELR K A N++ Sbjct: 245 IYFLDSGHLAGAALDVLPKEPPVAGDPIIHHPKIIITPHVAWYSEESEKELRYKWAMNVV 304 Query: 302 DWDRTGRPSYVVVQ 315 + + G P Y VV Sbjct: 305 AFLKNGSPLYPVVM 318 >ref|NP_693741.1| dehydrogenase [Oceanobacillus iheyensis HTE831] dbj|BAC14775.1| dehydrogenase [Oceanobacillus iheyensis HTE831] Length = 329 Score = 233 bits (595), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 125/304 (41%), Positives = 183/304 (60%), Gaps = 5/304 (1%) Query: 2 KVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVFA 61 KVLITD D +VD+E +K+A + QC+TEE++I+ G + + QYAPV V Sbjct: 5 KVLITDCDHGNVDVESETFKKAEISFDLEQCKTEEDLISKGKGFEVFINQYAPVTRSVIE 64 Query: 62 ARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVYD 121 P++++ RYG G D ++ A A HGV V N PDYG+ EVA ALAM L+ R+I+ + Sbjct: 65 NLPDLKLVVRYGVGVDNVDIAAATEHGVQVCNVPDYGMNEVADQALAMMLNFTRSISRMN 124 Query: 122 RAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIID---G 178 V+ G W Y + + R S+ T+G+IG+GRIG A ++L RV+AYDP +D Sbjct: 125 SFVRKGVWDYQKSMPLYRHSEQTVGVIGVGRIGSSFAKKVKSLGCRVVAYDPKYLDEKAK 184 Query: 179 DFPAYV-ERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVK 237 P ++ E + EL QA VVS+H PL D+ RN+ID L ++ +YL+N +RGG++ Sbjct: 185 KSPDFIDEFLPLNELLEQADVVSIHCPL-DKARNLIDEKELQKMKPTAYLINVSRGGIIN 243 Query: 238 IDDLLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAA 297 L AL N + GAA+DV EP Q SA+++H + +PH ++S+ AA EL+RK A Sbjct: 244 EQALNKALTNQWIAGAAVDVAENEPLQPESALLEHDNFICTPHMGWYSEQAALELKRKVA 303 Query: 298 QNLI 301 + I Sbjct: 304 EESI 307 >ref|YP_003991614.1| d-isomer specific 2-hydroxyacid dehydrogenase nad-binding protein [Caldicellulosiruptor hydrothermalis 108] gb|ADQ06245.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Caldicellulosiruptor hydrothermalis 108] Length = 332 Score = 229 bits (583), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 116/314 (36%), Positives = 188/314 (59%), Gaps = 1/314 (0%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 +KV++TD+++ D+ E ++ AG+ ++ AQCRTE+E+I GLL QYA + +V Sbjct: 4 LKVVVTDFEYSDLRYEEEVFNSAGITLIPAQCRTEDELITVCKEADGLLSQYAQITRRVI 63 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 + P+ ++ RYG G +TI+ A G+ V N PDY + EV+ HALA+ L L R I + Sbjct: 64 ESLPKCKVIGRYGVGVNTIDIEAATEKGICVVNVPDYCMDEVSDHALALILTLARKIVLL 123 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 + +VK G W Y + I R +G++G GRI + +A ++++ ++ YDPYI D Sbjct: 124 NNSVKKGIWDYKISKPIYRLRGKVLGLVGFGRIPRTLAQKAKSIGFNILVYDPYISPNDA 183 Query: 181 PAY-VERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKID 239 AY + V +EL Q+ +S+H PLN ET ++I L L++ ++L+N+ARG ++ Sbjct: 184 EAYGAKLVSLDELMTQSDFISIHVPLNKETYHLIGPQELKLMKPTAFLINTARGPVIDEK 243 Query: 240 DLLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQN 299 L+ L ++ GAALDV VEP Q+ + +++ V+++PH A++S+ A ELR KAAQ Sbjct: 244 ALIEVLLEKRIAGAALDVTEVEPIQSDNPLLKMDNVIITPHVAWYSEEAEAELRTKAAQG 303 Query: 300 LIDWDRTGRPSYVV 313 + D P Y+V Sbjct: 304 IADVLLGYWPRYLV 317 >ref|ZP_07931609.1| D-isomer specific 2-hydroxyacid dehydrogenase [Anaerostipes sp. 3_2_56FAA] gb|EFV22224.1| D-isomer specific 2-hydroxyacid dehydrogenase [Anaerostipes sp. 3_2_56FAA] Length = 317 Score = 229 bits (583), Expect = 6e-58, Method: Compositional matrix adjust. Identities = 120/304 (39%), Positives = 182/304 (59%), Gaps = 2/304 (0%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 MKV+ITD D ++D+E ++ +AG+++ Q TE EVIA + +VQYA + KV Sbjct: 1 MKVIITDCDHENIDIETKIFADAGIDMELKQAVTENEVIAQCQNAEIFIVQYAKITEKVM 60 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 P+++ RYG G DTI+ A A HGV V N PDYG+ EVA HA+++AL +IR I Sbjct: 61 EHCPKLKYVVRYGVGVDTIDLAAAQKHGVQVGNVPDYGMNEVADHAISLALAMIRKIVKM 120 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYI-IDGD 179 + K W YT A + R S+LT+G+IGLGRIG+ A L VI DPY + Sbjct: 121 NAVTKNEGWDYTNAIPVHRFSELTVGVIGLGRIGRNFAKKMHALGFSVIGTDPYYKAASE 180 Query: 180 FPAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKID 239 YV+ V EE+ +++ ++SLH P D ++ + ++ + L+N ARGG++ Sbjct: 181 TDRYVQTVSMEEVIKRSDIISLHCPA-DGNVDLFNKETFRKMKKSAILINVARGGIINEP 239 Query: 240 DLLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQN 299 DL AL+NG++ GAALD + EP AS + +H ++++PH A++S+ AA EL+RK A+ Sbjct: 240 DLNQALKNGEIAGAALDCMLGEPVSKASVLFKHENLIVTPHMAWYSEEAADELKRKVAEE 299 Query: 300 LIDW 303 + + Sbjct: 300 AVRF 303 >ref|ZP_08599488.1| D-3-phosphoglycerate dehydrogenase [Fusobacterium sp. 11_3_2] gb|EGN66827.1| D-3-phosphoglycerate dehydrogenase [Fusobacterium sp. 11_3_2] Length = 316 Score = 228 bits (582), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 108/313 (34%), Positives = 181/313 (57%), Gaps = 1/313 (0%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 MKV+ITD D +D+E ++ EA +E QC+TEE++I + QYAP+ KV Sbjct: 1 MKVIITDCDHTSIDIEKKIFNEANLEFELKQCKTEEDLINQCKDGDIFINQYAPITRKVM 60 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 P +++ RYG G + ++ A G+ + N PDYG EVA A+AM + L+R + + Sbjct: 61 EKLPNLKMVVRYGVGVNNVDIGGATDLGIQICNVPDYGTNEVADQAIAMMMALVRKVVIM 120 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 D+ K +W YT + I R S++T+G++GLGRIG A + L +I YDPY + + Sbjct: 121 DKYTKEVKWDYTHSIPIKRNSEMTVGVVGLGRIGCNFAQKAHYLGFNIIGYDPYYKENEE 180 Query: 181 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD 240 ++ +E+ +++ ++S+H PL D +N+ DA+ ++ +Y++N +RGG++ D Sbjct: 181 TKFIIPATIDEIIKRSDIISIHCPL-DGNKNLFDATAFKCMKKTAYIINVSRGGIINEKD 239 Query: 241 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQNL 300 L AL N ++ GAALD + EP S +++H +++SPH ++S+ AA EL+ K A+ Sbjct: 240 LDEALTNKEIAGAALDCVEFEPMMPTSPLLKHENLIISPHMGWYSEEAALELKHKVAEEA 299 Query: 301 IDWDRTGRPSYVV 313 + + R Y V Sbjct: 300 VRFASGERVHYPV 312 >ref|ZP_07930558.1| D-isomer specific 2-hydroxyacid dehydrogenase [Anaerostipes sp. 3_2_56FAA] gb|EFV23279.1| D-isomer specific 2-hydroxyacid dehydrogenase [Anaerostipes sp. 3_2_56FAA] Length = 322 Score = 228 bits (582), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 124/301 (41%), Positives = 184/301 (61%), Gaps = 1/301 (0%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 MKV+ITD D ++D+E + +AG+E RTE+EVI AG +VQYA ++ KV Sbjct: 1 MKVIITDCDHENIDIETKVLSDAGIEFKLTCARTEDEVIEQCAGADIFIVQYANISEKVM 60 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 A PE++ RYG G DT++ AA +G+ V N PDYG+ EVA HALA+ L ++R Sbjct: 61 KALPELKYVVRYGVGVDTVDLKAAAEYGIQVGNVPDYGMNEVADHALALLLMMLRKTDQM 120 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 +R K W YT + I R S+ T+G++GLGRIG+ A + L RVI YDP + G+ Sbjct: 121 NRFTKTTGWDYTQSIPIRRFSEQTVGVVGLGRIGRNFAEKAAALGFRVIGYDPMVNQGER 180 Query: 181 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD 240 E V EEL +Q+ VSLH P D +N+ D +++ + +VN+ARGG++ +D Sbjct: 181 IGNAEAVSFEELLKQSDAVSLHCPA-DGNQNLFDMEAFRVMKDSAVIVNAARGGIINEED 239 Query: 241 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQNL 300 L AL+ + GAALD + EP T S+I ++ ++++PH A++S+ AA EL+RKAA+ Sbjct: 240 LDRALKEKVIAGAALDCMKSEPMMTDSSIFENENLIVTPHMAWYSEEAAMELKRKAAEEA 299 Query: 301 I 301 + Sbjct: 300 V 300 >ref|ZP_02419587.1| hypothetical protein ANACAC_02181 [Anaerostipes caccae DSM 14662] gb|EDR96951.1| hypothetical protein ANACAC_02181 [Anaerostipes caccae DSM 14662] Length = 322 Score = 226 bits (575), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 123/301 (40%), Positives = 183/301 (60%), Gaps = 1/301 (0%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 MKV+ITD D ++D+E + +AG+E RTE+EVI AG +VQYA ++ KV Sbjct: 1 MKVIITDCDHENIDIETKVLSDAGIEFKLTCARTEDEVIEQCAGADIFIVQYANISEKVM 60 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 A PE++ RYG G DT++ AA +G+ V N PDYG+ EVA HALA+ L ++R Sbjct: 61 KALPELKYVVRYGVGVDTVDLKAAAEYGIQVGNVPDYGMNEVADHALALLLMMLRKTDQM 120 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 +R K W YT A I R S+ T+G++GLGRIG+ A + L RVI YDP + G+ Sbjct: 121 NRFTKTTGWDYTQAIPIRRFSEQTVGVVGLGRIGRNFAEKAAALGFRVIGYDPMVNQGER 180 Query: 181 PAYVERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKIDD 240 E V +EL +Q+ VSLH P D +N+ D +++ + +VN+ARGG++ +D Sbjct: 181 IGNAEAVSFQELLKQSDAVSLHCPA-DGNQNLFDMEAFRVMKDSAVIVNAARGGIINEED 239 Query: 241 LLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQNL 300 L AL+ + GAALD + EP S+I ++ ++++PH A++S+ AA EL+RKAA+ Sbjct: 240 LDRALKEKVIAGAALDCMKSEPMMPDSSIFENENLIVTPHMAWYSEEAAMELKRKAAEEA 299 Query: 301 I 301 + Sbjct: 300 V 300 >ref|YP_004820408.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Thermoanaerobacter wiegelii Rt8.B1] gb|AEM79124.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Thermoanaerobacter wiegelii Rt8.B1] Length = 331 Score = 225 bits (574), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 115/314 (36%), Positives = 188/314 (59%), Gaps = 1/314 (0%) Query: 1 MKVLITDYDFPDVDLELALYKEAGVEVVTAQCRTEEEVIAASAGCQGLLVQYAPVNAKVF 60 +KV++TD++F D+ E + KEAG+ ++ AQC++EEE+I+ GL+ QYA + +V Sbjct: 4 LKVVVTDFEFGDLRYEERVLKEAGITLIPAQCKSEEELISVCKDADGLINQYAKITRRVI 63 Query: 61 AARPEIRIASRYGAGFDTINTADAAAHGVWVANSPDYGVGEVATHALAMALDLIRNITVY 120 A ++ +RYG G DTI+ A A G+ V N PDY + EV+ HALA+ L R + + Sbjct: 64 EALDNCKVIARYGVGVDTIDIKAATARGICVVNVPDYCMDEVSDHALALLLGCARKVVLM 123 Query: 121 DRAVKAGQWHYTTAGIIPRASDLTIGIIGLGRIGKRMAHISRNLFKRVIAYDPYIIDGDF 180 + AVKAG W + + I R +G++G GRI + +A +R ++ YDPYI D Sbjct: 124 NNAVKAGTWDFKISKPIYRLRGKVLGLVGFGRIPRTLAEKARPFGFDILVYDPYITQADV 183 Query: 181 PAY-VERVGREELFRQAHVVSLHTPLNDETRNMIDASLLDLLQAQSYLVNSARGGLVKID 239 Y VG EEL ++ VS+H PL ++T ++I + + L++ ++++N+ARG ++ Sbjct: 184 EPYGATLVGLEELMAKSDFVSVHAPLTEKTYHLIGETEIGLMKPSAFIINTARGPVIDEK 243 Query: 240 DLLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVLLSPHAAFFSDVAARELRRKAAQN 299 L+ AL+ ++ GA LDVL EP + + +++ V+++PH A++S+ A ELR KAAQ Sbjct: 244 ALIKALQEKRIAGAGLDVLEQEPTPSDNPLLKMDNVIITPHVAWYSEEAEAELRTKAAQG 303 Query: 300 LIDWDRTGRPSYVV 313 + D P Y+V Sbjct: 304 VADVLLGYWPKYLV 317