BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0006.p (238 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777068.1| GGDEF family protein [Herbaspirillum seroped... 482 e-134 ref|YP_260413.1| GAF domain/diguanylate cyclase domain-containin... 264 9e-69 ref|YP_347908.1| GAF sensor-containing diguanylate cyclase [Pseu... 257 1e-66 ref|ZP_02886580.1| diguanylate cyclase with GAF sensor [Burkhold... 248 6e-64 ref|YP_001896504.1| GAF sensor-containing diguanylate cyclase [B... 239 3e-61 ref|YP_004354614.1| Diguanylate cyclase [Pseudomonas brassicacea... 239 3e-61 gb|EDZ40375.1| Diguanylate cyclase with GAF sensor [Leptospirill... 237 1e-60 ref|YP_943086.1| bifunctional adenylate cyclase/hybrid sensor di... 236 2e-60 ref|YP_001858577.1| GAF sensor-containing diguanylate cyclase [B... 236 3e-60 ref|ZP_01736357.1| Putative diguanylate cyclase (GGDEF domain) w... 234 6e-60 >ref|YP_003777068.1| GGDEF family protein [Herbaspirillum seropedicae SmR1] gb|ADJ65160.1| GGDEF family protein [Herbaspirillum seropedicae SmR1] Length = 324 Score = 482 bits (1241), Expect = e-134, Method: Compositional matrix adjust. Identities = 236/238 (99%), Positives = 236/238 (99%) Query: 1 MTIVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERA 60 MTIVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERA Sbjct: 87 MTIVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERA 146 Query: 61 LLKDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQ 120 LLKDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQ Sbjct: 147 LLKDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQ 206 Query: 121 FKQINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAH 180 FKQINDRFGHAEGDAALVDFAALLSSSFRESDVI RLGGDEFAVFLTNADLAESDTVLAH Sbjct: 207 FKQINDRFGHAEGDAALVDFAALLSSSFRESDVIARLGGDEFAVFLTNADLAESDTVLAH 266 Query: 181 FAQSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKARRAQAG 238 FAQSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKK RRAQAG Sbjct: 267 FAQSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKTRRAQAG 324 >ref|YP_260413.1| GAF domain/diguanylate cyclase domain-containing protein [Pseudomonas fluorescens Pf-5] gb|AAY92577.1| GAF domain/diguanylate cyclase domain protein [Pseudomonas fluorescens Pf-5] Length = 322 Score = 264 bits (674), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 131/231 (56%), Positives = 163/231 (70%) Query: 4 VPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALLK 63 VPDA LD RF NP V G P IRFYAGCP+ +G LGTLCL+D PR D ++RALL+ Sbjct: 89 VPDAGLDERFHDNPLVVGAPGIRFYAGCPLTVTNGSKLGTLCLIDIKPRDLDDEDRALLR 148 Query: 64 DLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFKQ 123 DLA M EQEL AV+MA++DELT +SNRRGF+ALARHAL +R++ PA +L+FDL+ FKQ Sbjct: 149 DLARMAEQELAAVQMASMDELTLLSNRRGFEALARHALGVCKRLEKPATLLFFDLNDFKQ 208 Query: 124 INDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFAQ 183 IND +GHAEGD AL FA +L +FRESDVIGRLGGDEF LT AD E+ ++A + Sbjct: 209 INDTYGHAEGDGALKTFADVLRIAFRESDVIGRLGGDEFVALLTAADHVETSAIMARLRE 268 Query: 184 SVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKARR 234 + E N R Y + +SVG ++YDA RH D+ AL AD MY K+A + Sbjct: 269 ILDERNATLKRGYDIRFSVGQIEYDAERHPDIEALLADADKAMYLHKQASK 319 >ref|YP_347908.1| GAF sensor-containing diguanylate cyclase [Pseudomonas fluorescens Pf0-1] gb|ABA73919.1| putative GGDEF/GAF domain sensory box protein [Pseudomonas fluorescens Pf0-1] Length = 321 Score = 257 bits (657), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 127/232 (54%), Positives = 162/232 (69%) Query: 1 MTIVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERA 60 + +VPDA D RF NP VTGEP IRFYAG P+ SG +GTLCL+DT PR D +ERA Sbjct: 86 LMLVPDAREDERFHDNPLVTGEPNIRFYAGYPLTVPSGNKMGTLCLIDTKPRDLDEEERA 145 Query: 61 LLKDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQ 120 LL+DLA M EQEL AV+MA++DELT +SNRRGF LA+HAL R++ PA +L+FDL+ Sbjct: 146 LLRDLAGMAEQELMAVQMASMDELTLLSNRRGFKMLAQHALDACARLEKPATLLFFDLND 205 Query: 121 FKQINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAH 180 FKQIND +GHAEGD+AL FA +L +FRESDV+GRLGGDEF LT + E+ ++A Sbjct: 206 FKQINDLYGHAEGDSALKTFADVLRIAFRESDVVGRLGGDEFVALLTGSSHVETTAIMAR 265 Query: 181 FAQSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKA 232 + + E N R YA+ +SVG ++Y+ RH + L ADA MYE K+A Sbjct: 266 LKEILEERNATLHRGYAIRFSVGQIEYNPQRHESVDKLLADADAAMYEHKQA 317 >ref|ZP_02886580.1| diguanylate cyclase with GAF sensor [Burkholderia graminis C4D1M] gb|EDT07809.1| diguanylate cyclase with GAF sensor [Burkholderia graminis C4D1M] Length = 326 Score = 248 bits (633), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 131/235 (55%), Positives = 163/235 (69%) Query: 4 VPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALLK 63 VPD D RF NP VT P IRFYAGCP+ +G LGTLCL+D PR D +ER LL+ Sbjct: 89 VPDTLADERFHDNPLVTEAPNIRFYAGCPLTVPNGSRLGTLCLIDVKPRELDDEERELLR 148 Query: 64 DLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFKQ 123 DLA M EQEL AV++AT+D+LT +SNRRGF ALA+HAL +R+D PA +L+FDL+ FKQ Sbjct: 149 DLARMAEQELAAVQLATLDDLTLLSNRRGFSALAQHALNVCKRLDRPASLLFFDLNDFKQ 208 Query: 124 INDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFAQ 183 IND FGHAEGD AL FA +L + RESDVIGRLGGDEF V L++ D A + V Sbjct: 209 INDTFGHAEGDHALKTFADVLRGTLRESDVIGRLGGDEFVVLLSDTDAAATQEVTERLTH 268 Query: 184 SVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKARRAQAG 238 S+ E N R Y++ +SVG ++YDAARH +A L +ADA MY K+A +A+A Sbjct: 269 SLDERNAQAQRGYSIRFSVGQIEYDAARHGSIAELLSAADAAMYSHKQASKARAA 323 >ref|YP_001896504.1| GAF sensor-containing diguanylate cyclase [Burkholderia phytofirmans PsJN] gb|ACD17280.1| diguanylate cyclase with GAF sensor [Burkholderia phytofirmans PsJN] Length = 326 Score = 239 bits (610), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 132/238 (55%), Positives = 163/238 (68%) Query: 1 MTIVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERA 60 + +VPD D RF NP VT P IRFYAGCP+ +G LGTLCL+DT PR D +ER Sbjct: 86 ILMVPDTLADERFHDNPLVTDNPSIRFYAGCPLTVPNGSKLGTLCLIDTKPRGLDEEERQ 145 Query: 61 LLKDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQ 120 LL+DLA M EQEL AV++AT+D+LT +SNRRGF+ALA+HAL +RM PA +L+FDL+ Sbjct: 146 LLRDLARMAEQELAAVQLATLDDLTLLSNRRGFEALAQHALNVCKRMHKPASLLFFDLND 205 Query: 121 FKQINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAH 180 FKQIND GHAEGD AL FA +L ++ RESDVIGRLGGDEF V LT++D + V Sbjct: 206 FKQINDTLGHAEGDRALKTFADVLRTALRESDVIGRLGGDEFVVLLTDSDSGATQEVTQR 265 Query: 181 FAQSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKARRAQAG 238 Q + N R Y + YSVG VQYD ARH +A L +ADA MY K+A +A+A Sbjct: 266 LTQMLDARNAEAQRGYHIRYSVGQVQYDCARHQSIAELLAAADAAMYSHKQASKARAA 323 >ref|YP_004354614.1| Diguanylate cyclase [Pseudomonas brassicacearum subsp. brassicacearum NFM421] gb|AEA69610.1| putative Diguanylate cyclase [Pseudomonas brassicacearum subsp. brassicacearum NFM421] Length = 324 Score = 239 bits (609), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 122/232 (52%), Positives = 156/232 (67%) Query: 4 VPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALLK 63 + DA D RF NP VT +P IRFYAG P+ E G LGTLCL+DT PR + +ER LL+ Sbjct: 93 ICDAEQDERFHDNPLVTDKPGIRFYAGHPLGMEDGSKLGTLCLLDTKPRKLNDEERELLR 152 Query: 64 DLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFKQ 123 DLA M EQE+ AV+MA++DELT +SNRRGF LA+HAL R+ PA +L+FDL+ FK Sbjct: 153 DLARMAEQEMVAVQMASMDELTLLSNRRGFRTLAQHALNVCDRLSRPATLLFFDLNDFKP 212 Query: 124 INDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFAQ 183 INDR+GHAEGD AL FA +L +FRESDVIGRLGGDEF LT + E ++A + Sbjct: 213 INDRYGHAEGDNALKTFADVLRIAFRESDVIGRLGGDEFVALLTGSSHVEIAAIMARLQE 272 Query: 184 SVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKARRA 235 + E N + R Y + +SVG ++YD RH + L ADA MY +K+A R+ Sbjct: 273 ILDERNAMLQRGYDIRFSVGQIEYDPQRHQSIDMLLADADAAMYAQKQALRS 324 >gb|EDZ40375.1| Diguanylate cyclase with GAF sensor [Leptospirillum sp. Group II '5-way CG'] Length = 322 Score = 237 bits (604), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 113/231 (48%), Positives = 157/231 (67%) Query: 3 IVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALL 62 I+PDA DPRFS NP V G+P IRFYAGC ++++ +GTLCL+D PR+ + + +L Sbjct: 88 IIPDARSDPRFSDNPLVLGDPRIRFYAGCVLRTQDNQKIGTLCLIDHEPRAMEPQDLLVL 147 Query: 63 KDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFK 122 +DL ++ EQEL+A++MAT+DELTG+SNRRGF +LARH+LA S R D P + + DLD+FK Sbjct: 148 EDLTSLAEQELSALKMATMDELTGLSNRRGFLSLARHSLALSERHDLPMSLAFLDLDKFK 207 Query: 123 QINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFA 182 IND FGHAEGD AL FA L+ +FR SD+I RLGGDEF V L ++ S ++ Sbjct: 208 PINDSFGHAEGDRALRSFADLMKRTFRTSDLIARLGGDEFVVLLIGSNRETSGELMVRLG 267 Query: 183 QSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKAR 233 + E + L R Y +A+S G+V++D RH + + DALMY+ K+ + Sbjct: 268 TAAEEASRLENRGYDIAFSHGIVEFDPVRHRSIEEMLAEGDALMYQIKQKK 318 >ref|YP_943086.1| bifunctional adenylate cyclase/hybrid sensor diguanylate cyclase/response regulator [Psychromonas ingrahamii 37] gb|ABM03487.1| diguanylate cyclase with GAF sensor [Psychromonas ingrahamii 37] Length = 316 Score = 236 bits (603), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 113/228 (49%), Positives = 156/228 (68%) Query: 3 IVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALL 62 I+PD D RFS NP V EP+IRFYAGCP++ G TLGTLC++DT PR D ++ L Sbjct: 88 IIPDTIKDERFSDNPLVLNEPYIRFYAGCPLRYLDGSTLGTLCIIDTQPRVLDEEDLDAL 147 Query: 63 KDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFK 122 KDLA + E EL AV++AT DELT +SNRRGF LA+H L R + A +++FDL++FK Sbjct: 148 KDLAELAEHELMAVQLATQDELTKLSNRRGFIKLAQHGLDICARHNISASLVFFDLNKFK 207 Query: 123 QINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFA 182 IND FGHAEGDAAL+ F+ + ++FR+SD+IGRLGGDEFAV LT+ L ++ ++ F Sbjct: 208 SINDTFGHAEGDAALLAFSDHMKNTFRDSDIIGRLGGDEFAVLLTDTSLEPAEKTISRFR 267 Query: 183 QSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERK 230 S+ +N Y +++S G+V+ D ++ L +L AD+LMY+ K Sbjct: 268 SSIEHYNKESNLGYEISFSEGIVEIDHEKNISLESLLGQADSLMYDNK 315 >ref|YP_001858577.1| GAF sensor-containing diguanylate cyclase [Burkholderia phymatum STM815] gb|ACC71531.1| diguanylate cyclase with GAF sensor [Burkholderia phymatum STM815] Length = 319 Score = 236 bits (601), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 121/232 (52%), Positives = 156/232 (67%) Query: 3 IVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALL 62 +V DA+LD RF+ NP VTG+P IRFYAG P+ +G LGTLCL+D PR+ D +ER LL Sbjct: 88 LVNDASLDVRFADNPLVTGDPNIRFYAGYPLTVSNGSRLGTLCLIDVKPRALDDEERVLL 147 Query: 63 KDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFK 122 +DLA M EQE+ AV++AT DELTG+SNRRGF+ALA+HA+ + +R PA +L+FDL+ FK Sbjct: 148 RDLARMAEQEIAAVQLATTDELTGLSNRRGFEALAQHAIKHCKRAQKPASLLFFDLNGFK 207 Query: 123 QINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFA 182 QIND FGHAEGD AL+ FAA+L ++ R+SDVIGRLGGDEF V LT++D + + Sbjct: 208 QINDVFGHAEGDRALIAFAAVLRTALRDSDVIGRLGGDEFVVLLTDSDQQGTLQTIERLR 267 Query: 183 QSVREFNVLRPRPYALAYSVGVVQYDAARHADLAALQHSADALMYERKKARR 234 + N PY L SVG Y + L AD MY K+A+R Sbjct: 268 HQLDLQNQSAQAPYQLHCSVGTATYTPDSPRSIDDLLAQADVAMYANKRAQR 319 >ref|ZP_01736357.1| Putative diguanylate cyclase (GGDEF domain) with GAF sensor domain [Marinobacter sp. ELB17] gb|EBA00619.1| Putative diguanylate cyclase (GGDEF domain) with GAF sensor domain [Marinobacter sp. ELB17] Length = 319 Score = 234 bits (598), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 117/232 (50%), Positives = 155/232 (66%), Gaps = 4/232 (1%) Query: 3 IVPDATLDPRFSGNPQVTGEPFIRFYAGCPIKSESGFTLGTLCLVDTVPRSFDADERALL 62 I+PDA D RF+ NP VT P IRFYAG P++ G +GTLCL+D PR D +++ L Sbjct: 88 IIPDAIEDVRFADNPLVTDAPNIRFYAGYPLEIREGLKIGTLCLIDQKPRVMDEEDQQLF 147 Query: 63 KDLAAMVEQELTAVRMATIDELTGISNRRGFDALARHALANSRRMDWPACMLYFDLDQFK 122 KDL AMVEQE+ ++++AT+DELT ISNRRGF LA + L RR L FDL++FK Sbjct: 148 KDLGAMVEQEIKSIQLATLDELTLISNRRGFLNLADYGLKMCRRNRVSMSFLLFDLNKFK 207 Query: 123 QINDRFGHAEGDAALVDFAALLSSSFRESDVIGRLGGDEFAVFLTNADLAESDTVLAHFA 182 IND++GH EGD L FA +L +FR+SDVIGRLGGDEF LT++D SD +LA FA Sbjct: 208 AINDQYGHHEGDFVLTKFARILLDTFRDSDVIGRLGGDEFVAMLTDSDKKNSDEILARFA 267 Query: 183 QSVREFNVLRPRPYALAYSVGV--VQYDAARHADLAALQHSADALMYERKKA 232 ++V+E N +PY + YSVG+ Q+D + A+ + ADA MY+ KK+ Sbjct: 268 EAVKETNATMNKPYKIEYSVGIEHFQHDTTKTAE--EMIQEADAAMYKHKKS 317