BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0035.p (260 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773945.1| two-component response regulator with GGDEF ... 506 e-142 ref|YP_003157981.1| diguanylate cyclase [Desulfomicrobium bacula... 169 3e-40 ref|YP_002947547.1| diguanylate cyclase [Variovorax paradoxus S1... 164 2e-38 ref|YP_004752514.1| putative GGDEF domain-containing protein [Co... 163 2e-38 ref|YP_001479297.1| diguanylate cyclase [Serratia proteamaculans... 157 1e-36 ref|YP_349529.1| diguanylate cyclase [Pseudomonas fluorescens Pf... 156 3e-36 ref|ZP_01620129.1| Putative diguanylate cyclase (GGDEF domain) [... 154 2e-35 ref|YP_340205.1| hypothetical protein PSHAa1689 [Pseudoalteromon... 152 4e-35 ref|YP_004353014.1| diguanylate cyclase [Pseudomonas brassicacea... 152 4e-35 ref|YP_001865185.1| diguanylate cyclase with PAS/PAC and GAF sen... 152 4e-35 >ref|YP_003773945.1| two-component response regulator with GGDEF domain [Herbaspirillum seropedicae SmR1] gb|ADJ62037.1| two-component response regulator with GGDEF domain (diguanylate cyclase) protein [Herbaspirillum seropedicae SmR1] Length = 277 Score = 506 bits (1304), Expect = e-142, Method: Compositional matrix adjust. Identities = 259/260 (99%), Positives = 260/260 (100%) Query: 1 MVLLTAAVLTVLATTAPASMVVAAIALVLAAALLSWLLLRQLLRPLSGLEANLQALQQER 60 MVLLTAAVLTVLATTAPASMVVAAIALVLAAALLSWLLLRQLLRPLSGLEANLQALQQER Sbjct: 18 MVLLTAAVLTVLATTAPASMVVAAIALVLAAALLSWLLLRQLLRPLSGLEANLQALQQER 77 Query: 61 VQLVEERDDARVHLEEMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVI 120 VQLVEERDDARVHLEEMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVI Sbjct: 78 VQLVEERDDARVHLEEMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVI 137 Query: 121 MIDIDLFDEYNESYGRMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEG 180 MIDIDLFDEYN+SYGRMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEG Sbjct: 138 MIDIDLFDEYNDSYGRMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEG 197 Query: 181 ALIVAERIRKSIELLDIPHSASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAK 240 ALIVAERIRKSIELLDIPHSASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAK Sbjct: 198 ALIVAERIRKSIELLDIPHSASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAK 257 Query: 241 SAGRDCIRTVEDLRRMRGQA 260 SAGRDCIRTVEDLRRMRGQA Sbjct: 258 SAGRDCIRTVEDLRRMRGQA 277 >ref|YP_003157981.1| diguanylate cyclase [Desulfomicrobium baculatum DSM 4028] gb|ACU89565.1| diguanylate cyclase [Desulfomicrobium baculatum DSM 4028] Length = 339 Score = 169 bits (429), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 89/213 (41%), Positives = 134/213 (62%), Gaps = 5/213 (2%) Query: 36 WLLLRQLLRPLSGLEANLQALQQERVQLVEERDDARVHLEEMEKTLARVGLEDALTGLAN 95 W + R L R L A + +Q ++++ + LEE L+ + L D LTG+AN Sbjct: 125 WGMARDLTRFLVSQNALVHLNEQLEAKILQRTRE----LEEANHRLSELSLTDGLTGIAN 180 Query: 96 RRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEYNESYGRMAGDKVLRRVGSAIRDTNV 155 RR+F+ L EE++R+ART +LA+IM+DID F +YN+ YG GD LRRV +R + Sbjct: 181 RRRFDAALAEEWSRSARTGSTLALIMLDIDHFKKYNDHYGHQQGDDCLRRVAEVLRSSAR 240 Query: 156 RPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRKSIELLDIPHSASPTGRVTISIGISS 215 R DL+SR+G +E ++LP + L GA +AER+R+ +E +D+PH S GRVT S+G+++ Sbjct: 241 RQGDLVSRYGGEEFCMILPDTALPGAFEIAERLRREVENMDMPHVLSDVGRVTASMGVAA 300 Query: 216 VAPQRQVDEPETVLREAEESLALAKSAGRDCIR 248 P + + P +LR A+ESL AKS GR+C+R Sbjct: 301 SMPCKAM-SPAELLRRADESLYQAKSEGRNCVR 332 >ref|YP_002947547.1| diguanylate cyclase [Variovorax paradoxus S110] gb|ACS22281.1| diguanylate cyclase [Variovorax paradoxus S110] Length = 512 Score = 164 bits (414), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 92/233 (39%), Positives = 142/233 (60%), Gaps = 19/233 (8%) Query: 25 IALVLAAALLSWLLLRQLLRPLSGLEANLQALQQERVQLVEERDDARVHLEEMEKTLARV 84 + L L + W L+RQ Q + + E AR LE + KTL + Sbjct: 293 VLLSLIVGFIGWRLVRQF---------------QLQTRTEAELRQARDALETLNKTLNTL 337 Query: 85 GLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEYNESYGRMAGDKVLR 144 +ED LTGLANRRQF+ L E++RAAR + +LA+IM+D+D F +YN+ YG AGD+ L+ Sbjct: 338 AMEDGLTGLANRRQFDVALDSEYSRAARNASTLALIMMDVDCFKQYNDIYGHAAGDECLQ 397 Query: 145 RVGSAI-RDTNVRPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRKSIELLDIPHSASP 203 +G I R + RP DL +R+G +E+AVLLP + + GA+++AERIR ++ L I H+ + Sbjct: 398 TIGRTIARVASRRPGDLAARYGGEELAVLLPNTDVAGAVMLAERIRSAVRELKIEHAGTA 457 Query: 204 TGRVTISIGISSVAPQRQV-DEPETVLREAEESLALAKSAGRD--CIRTVEDL 253 G VT+S G+ +++PQ + +P+ ++R A+++L AKS GR+ C T + L Sbjct: 458 DGFVTLSAGVDALSPQAGIGGQPKELIRSADKALYAAKSGGRNRVCASTGQPL 510 >ref|YP_004752514.1| putative GGDEF domain-containing protein [Collimonas fungivorans Ter331] gb|AEK61691.1| putative GGDEF domain protein [Collimonas fungivorans Ter331] Length = 521 Score = 163 bits (413), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 86/201 (42%), Positives = 132/201 (65%), Gaps = 2/201 (0%) Query: 56 LQQERVQLVEERDDARVH--LEEMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAART 113 + Q R++L+ E D V L + + L ++ L+D+LTGLANRRQF+ L +EF+RA RT Sbjct: 321 IHQIRLRLLAENDLLCVQESLRMLNRHLEQLALQDSLTGLANRRQFDNALRDEFSRAMRT 380 Query: 114 SLSLAVIMIDIDLFDEYNESYGRMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLL 173 SLA++MID+D F +YN+ YG +AGD+ LR++ ++ + RP DL +R+G +E+ VLL Sbjct: 381 ENSLALVMIDVDYFKQYNDIYGHLAGDECLRQISEIVKASKNRPGDLAARYGGEELVVLL 440 Query: 174 PGSRLEGALIVAERIRKSIELLDIPHSASPTGRVTISIGISSVAPQRQVDEPETVLREAE 233 P + L GA+ VAE+IR +I L I H +S G VT+S G+ + P R + P +++ A+ Sbjct: 441 PDTNLAGAVAVAEKIRVAICNLHIEHPSSTFGLVTVSAGVDAFVPVRDDNIPFELIQAAD 500 Query: 234 ESLALAKSAGRDCIRTVEDLR 254 +L AKSAGR+ + + D R Sbjct: 501 RALYAAKSAGRNRVCSSADPR 521 >ref|YP_001479297.1| diguanylate cyclase [Serratia proteamaculans 568] gb|ABV42169.1| diguanylate cyclase [Serratia proteamaculans 568] Length = 516 Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 73/179 (40%), Positives = 117/179 (65%) Query: 71 RVHLEEMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEY 130 R L + +TL + L D LTGLANRRQF+ L E RA+R S+A++M+DID F +Y Sbjct: 337 RDQLTSINRTLEELALLDGLTGLANRRQFDIALKNELMRASRNYRSVALLMLDIDYFKQY 396 Query: 131 NESYGRMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRK 190 N+ YG +AGD+ L+++G ++ R D+++R+G +E+A++LP + +GALI AER+ + Sbjct: 397 NDIYGHVAGDQCLQQIGQMLKGMASRSNDIMARYGGEEMAIILPDTDAQGALIFAERVIE 456 Query: 191 SIELLDIPHSASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAKSAGRDCIRT 249 ++ L IPH +P G +TISIGI + P D P + + +A+ +L AK+ G++ I + Sbjct: 457 AVRELKIPHDGNPHGVITISIGIYAKVPHMYNDTPMSFINQADSALYQAKAQGKNRIYS 515 >ref|YP_349529.1| diguanylate cyclase [Pseudomonas fluorescens Pf0-1] gb|ABA75538.1| putative GGDEF domain protein [Pseudomonas fluorescens Pf0-1] Length = 553 Score = 156 bits (394), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 86/230 (37%), Positives = 131/230 (56%), Gaps = 29/230 (12%) Query: 18 ASMVVAAIALVLAAALLSWLLLRQLLRPLSGLEANLQALQQERVQLVEERDDARV--HLE 75 +S++VA + +L AL W+ + Q+ RD R+ +L Sbjct: 332 SSVIVALV--MLGVALFGWVFIHQV------------------------RDGERIEKNLR 365 Query: 76 EMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEYNESYG 135 + ++ L ++ D+LTGLANRR FER L EF R AR S +++IM+DID F YN++YG Sbjct: 366 KAQQALEQIATHDSLTGLANRRLFERSLEVEFARGARQSSPVSLIMLDIDFFKRYNDAYG 425 Query: 136 RMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRKSIELL 195 +AGD L +V +++ R DL R+G +E AVLLP + + GAL +A +IR+S+ Sbjct: 426 HVAGDHCLTQVAQVVKNCCQRKSDLAVRYGGEEFAVLLPDTDINGALAIAGQIRRSVMDK 485 Query: 196 DIPHSASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAKSAGRD 245 I HS SPTG +T+S+G + P D PE ++ A+ +L AK+AGR+ Sbjct: 486 HITHSGSPTGYLTVSLGCYAFIPTGN-DSPELFIQRADAALYQAKNAGRN 534 >ref|ZP_01620129.1| Putative diguanylate cyclase (GGDEF domain) [Lyngbya sp. PCC 8106] gb|EAW37970.1| Putative diguanylate cyclase (GGDEF domain) [Lyngbya sp. PCC 8106] Length = 346 Score = 154 bits (388), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 82/196 (41%), Positives = 119/196 (60%), Gaps = 9/196 (4%) Query: 53 LQALQQERVQLVEERDDARVHLEEMEKTLARVGLEDALTGLANRRQFERGLLEEFNRAAR 112 LQ + QE +L E L++ + L R+ + D+LT LANRRQF+ L+ E+ R R Sbjct: 144 LQQMNQELQRLAGE-------LQQANRELQRLAVTDSLTQLANRRQFDEYLIHEWLRMLR 196 Query: 113 TSLSLAVIMIDIDLFDEYNESYGRMAGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVL 172 L+VI+ D+D F YN+ YG AGD LR+V AI RP DL +R+G +E ++ Sbjct: 197 EQQFLSVILCDVDFFKNYNDKYGHPAGDNCLRKVAKAICQQVQRPGDLAARYGGEEFVII 256 Query: 173 LPGSRLEGALIVAERIRKSIELLDIPHSASPTGR-VTISIGISSVAPQRQVDEPETVLRE 231 LP ++ EGA+ VAE IR++I+ L+IPHS S +T+S G++SV PQ D P ++ Sbjct: 257 LPNTQAEGAINVAEGIRQAIKSLNIPHSQSKIADCITVSSGVASVVPQAN-DSPSNLIAT 315 Query: 232 AEESLALAKSAGRDCI 247 A+ +L AK GRDC+ Sbjct: 316 ADTALYEAKKKGRDCV 331 >ref|YP_340205.1| hypothetical protein PSHAa1689 [Pseudoalteromonas haloplanktis TAC125] emb|CAI86762.1| conserved protein of unknown function [Pseudoalteromonas haloplanktis TAC125] Length = 423 Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 71/167 (42%), Positives = 115/167 (68%), Gaps = 1/167 (0%) Query: 81 LARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEYNESYGRMAGD 140 L+ + D+LT +ANRR+F+ +++EF+R + L++I+IDID F ++N+ +G +AGD Sbjct: 252 LSEMAFLDSLTKIANRRRFDEKIVDEFSRVKLANCQLSLIIIDIDNFKKFNDRHGHIAGD 311 Query: 141 KVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRKSIELLDIPHS 200 K L V + DT RPED ++R+G +E VLLP + +GAL VAE+I+K+IE+L I H Sbjct: 312 KCLYAVAQKLADTVSRPEDFVARYGGEEFVVLLPQTDKQGALFVAEQIQKAIEMLAIVHE 371 Query: 201 ASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAKSAGRDCI 247 S TG +++S+GI++V Q D+ T ++ A+++L AK+ GR+CI Sbjct: 372 DSFTGYLSVSMGINTVN-HHQCDDHLTFIQAADDALYYAKNQGRNCI 417 >ref|YP_004353014.1| diguanylate cyclase [Pseudomonas brassicacearum subsp. brassicacearum NFM421] gb|AEA68010.1| Putative diguanylate cyclase [Pseudomonas brassicacearum subsp. brassicacearum NFM421] Length = 523 Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 88/228 (38%), Positives = 126/228 (55%), Gaps = 25/228 (10%) Query: 18 ASMVVAAIALVLAAALLSWLLLRQLLRPLSGLEANLQALQQERVQLVEERDDARVHLEEM 77 +S++V + VL L W+ +RQ+ R +EA+L+ QQ Sbjct: 302 SSLIVGLV--VLGICLFGWVFVRQV-RNSERIEADLRKAQQ------------------- 339 Query: 78 EKTLARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEYNESYGRM 137 L + D+LTGLANRR FER L EF R AR L++IM+DID F YN++YG + Sbjct: 340 --ALELIATHDSLTGLANRRLFERALDIEFGRGARQRSPLSLIMLDIDFFKRYNDAYGHV 397 Query: 138 AGDKVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRKSIELLDI 197 AGD L V ++D R DL R+G +E AVLLP + L GA+ +AE+IR+S+ I Sbjct: 398 AGDHCLAEVAKVLKDCCHRKADLAVRYGGEEFAVLLPDTNLSGAMALAEQIRRSVIDKHI 457 Query: 198 PHSASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAKSAGRD 245 HS SPTG +T+S+G + P +D E ++ A+ +L AK GR+ Sbjct: 458 THSGSPTGHLTVSLGCYAFVPS-GLDSIEVFIQRADAALYQAKHGGRN 504 >ref|YP_001865185.1| diguanylate cyclase with PAS/PAC and GAF sensors [Nostoc punctiforme PCC 73102] gb|ACC80242.1| diguanylate cyclase with PAS/PAC and GAF sensors [Nostoc punctiforme PCC 73102] Length = 888 Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 72/171 (42%), Positives = 118/171 (69%), Gaps = 2/171 (1%) Query: 81 LARVGLEDALTGLANRRQFERGLLEEFNRAARTSLSLAVIMIDIDLFDEYNESYGRMAGD 140 L R+ D LT +ANRR+F++ L E++R R + L++I+ D+D F YN++YG +AGD Sbjct: 713 LQRLATLDGLTQIANRRRFDQYLENEWHRLKREQMPLSLILFDVDFFKRYNDTYGHLAGD 772 Query: 141 KVLRRVGSAIRDTNVRPEDLLSRFGAQEIAVLLPGSRLEGALIVAERIRKSIELLDIPHS 200 LR++GSA++ RP DL++R+G +E AV+LP + +EGA+ VA+ IR+++ L IPH+ Sbjct: 773 DCLRQLGSALKSVIKRPADLVARYGGEEFAVILPNTEIEGAISVAQTIRQAVYDLIIPHA 832 Query: 201 -ASPTGRVTISIGISSVAPQRQVDEPETVLREAEESLALAKSAGRDCIRTV 250 +S RVT+S+G++S+ P + P+ ++ A++SL +AK GRD + TV Sbjct: 833 QSSVCDRVTVSLGVASIVPNCETS-PQDLINAADKSLYIAKQQGRDRVHTV 882