BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0174.p (265 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_558147.1| putative alcohol dehydrogenase, zinc-independen... 466 e-129 ref|ZP_06841549.1| short-chain dehydrogenase/reductase SDR [Burk... 464 e-129 ref|YP_708529.1| short chain dehydrogenase [Rhodococcus jostii R... 402 e-110 ref|YP_003200081.1| short-chain dehydrogenase/reductase SDR [Nak... 344 7e-93 ref|ZP_06483182.1| short chain dehydrogenase [Xanthomonas campes... 248 7e-64 ref|ZP_06491423.1| short chain dehydrogenase [Xanthomonas campes... 243 2e-62 ref|ZP_06483183.1| putative oxidoreductase, short- chain dehydro... 211 1e-52 ref|ZP_06841550.1| short-chain dehydrogenase/reductase SDR [Burk... 207 2e-51 ref|YP_558148.1| putative oxidoreductase, short- chain dehydroge... 206 3e-51 ref|YP_002247838.1| 3-oxoacyl-(acyl-carrier-protein) reductase [... 203 2e-50 >ref|YP_558147.1| putative alcohol dehydrogenase, zinc-independent [Burkholderia xenovorans LB400] gb|ABE30095.1| Putative alcohol dehydrogenase, zinc-independent [Burkholderia xenovorans LB400] Length = 265 Score = 466 bits (1200), Expect = e-129, Method: Compositional matrix adjust. Identities = 224/265 (84%), Positives = 242/265 (91%) Query: 1 MTRLKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIR 60 M RLK KVAI+TGASSGFGRGI A+A +GA +VVSD+HEAPN+GGFEGNP+LTT AAI Sbjct: 1 MERLKGKVAIVTGASSGFGRGIAMAYATEGASVVVSDIHEAPNQGGFEGNPQLTTAAAIT 60 Query: 61 ETGGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDAC 120 GG+A YV CDVTR D VA LV TV YG LD++VNNAGIYRAGKLAHEF+VE+LDAC Sbjct: 61 GAGGKAQYVACDVTRLDQVANLVKETVRLYGGLDVMVNNAGIYRAGKLAHEFSVEDLDAC 120 Query: 121 FDVNVKGTWFGCQEAIKQFLKQGDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANLTRCL 180 FDVNVKGTWFGCQEAIK FLKQ GGNI+NIVSTAGLQGHPKQSVYNISKGAAANLTRCL Sbjct: 121 FDVNVKGTWFGCQEAIKVFLKQARGGNIINIVSTAGLQGHPKQSVYNISKGAAANLTRCL 180 Query: 181 AIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLAVFLA 240 AIEYG+++IRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEV+DIA+LAVFLA Sbjct: 181 AIEYGRDRIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVEDIANLAVFLA 240 Query: 241 SDESSYIHGDLIRIDGGETLCRFSV 265 SDESSYIHGDLIRIDGGETLCRFSV Sbjct: 241 SDESSYIHGDLIRIDGGETLCRFSV 265 >ref|ZP_06841549.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. Ch1-1] gb|EFG70714.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. Ch1-1] Length = 265 Score = 464 bits (1193), Expect = e-129, Method: Compositional matrix adjust. Identities = 223/265 (84%), Positives = 241/265 (90%) Query: 1 MTRLKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIR 60 M RLK KVAI+TGASSGFGRGI A+A +GA +VVSD+HEAPN+GGFEGNP+LTT AAI Sbjct: 1 MERLKGKVAIVTGASSGFGRGIAMAYAAEGASVVVSDIHEAPNQGGFEGNPQLTTVAAIT 60 Query: 61 ETGGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDAC 120 GG+A YV CDVTR D VA LV TV YG LD++VNNAGIYRAGKLAHEFAVE+LD C Sbjct: 61 GAGGKAQYVACDVTRLDQVANLVKETVRLYGGLDVMVNNAGIYRAGKLAHEFAVEDLDVC 120 Query: 121 FDVNVKGTWFGCQEAIKQFLKQGDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANLTRCL 180 FDVNVKGTWFGCQEAIK FLKQ GGNI+NIVSTAGLQGHPKQSVYNISKGAAANLTRCL Sbjct: 121 FDVNVKGTWFGCQEAIKVFLKQARGGNIINIVSTAGLQGHPKQSVYNISKGAAANLTRCL 180 Query: 181 AIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLAVFLA 240 AIEYG+++IRVNGICPTYAKTSLTRALFDDKDFDKVFT+AIPLKRWGEV+DIA+LAVFLA Sbjct: 181 AIEYGRDRIRVNGICPTYAKTSLTRALFDDKDFDKVFTDAIPLKRWGEVEDIANLAVFLA 240 Query: 241 SDESSYIHGDLIRIDGGETLCRFSV 265 SDESSYIHGDLIRIDGGETLCRFSV Sbjct: 241 SDESSYIHGDLIRIDGGETLCRFSV 265 >ref|YP_708529.1| short chain dehydrogenase [Rhodococcus jostii RHA1] gb|ABH00371.1| probable short chain dehydrogenase [Rhodococcus jostii RHA1] Length = 265 Score = 402 bits (1034), Expect = e-110, Method: Compositional matrix adjust. Identities = 187/265 (70%), Positives = 225/265 (84%) Query: 1 MTRLKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIR 60 M RL++KV ++TG+SSG GRGI A A +GAK+V+SD+HE P GGFE + TT +I+ Sbjct: 1 MNRLQNKVIVVTGSSSGLGRGIAKACATEGAKLVISDIHEQPTTGGFEDDAAPTTAESIQ 60 Query: 61 ETGGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDAC 120 ++GG+A +V DVT++ +VA LV TV +GRLD+ +NNAGI+RAGK HEF+ +LD C Sbjct: 61 KSGGEAIFVQADVTKSTEVAALVKQTVAEFGRLDVFINNAGIFRAGKRLHEFSEADLDVC 120 Query: 121 FDVNVKGTWFGCQEAIKQFLKQGDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANLTRCL 180 FDVN KGT+FG QEAIKQFL QGDGGNIVNIVSTAGLQGHP QSVYNISKGA ANLTRCL Sbjct: 121 FDVNAKGTFFGAQEAIKQFLTQGDGGNIVNIVSTAGLQGHPNQSVYNISKGAQANLTRCL 180 Query: 181 AIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLAVFLA 240 AIEYG+++IRVNGICPTYAKT+LTR LFDD DFD FT++IPLKRWGE++D+A+LAVFLA Sbjct: 181 AIEYGKDQIRVNGICPTYAKTALTRELFDDTDFDTSFTDSIPLKRWGEIEDVANLAVFLA 240 Query: 241 SDESSYIHGDLIRIDGGETLCRFSV 265 SDESSYIHGDLI+IDGGETLCR+SV Sbjct: 241 SDESSYIHGDLIKIDGGETLCRYSV 265 >ref|YP_003200081.1| short-chain dehydrogenase/reductase SDR [Nakamurella multipartita DSM 44233] gb|ACV77092.1| short-chain dehydrogenase/reductase SDR [Nakamurella multipartita DSM 44233] Length = 270 Score = 344 bits (883), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 172/269 (63%), Positives = 206/269 (76%), Gaps = 6/269 (2%) Query: 3 RLKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIRET 62 RL+DKVA+ITGASSGFGR FA +GA +VV+D+ + P GFE + E T IR Sbjct: 2 RLRDKVAVITGASSGFGRAAALLFAAEGASVVVADIIDKPLPKGFEDDLEHPTDELIRSK 61 Query: 63 GGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDACFD 122 GGQA +V CDVTR D VAA VE +GRLD++ NNAGIYR GKL EF E+LDACF+ Sbjct: 62 GGQAVFVRCDVTRKADTDAAVAAAVESFGRLDVMFNNAGIYRGGKLFDEFTEEDLDACFN 121 Query: 123 VNVKGTWFGCQEAIKQFLKQ------GDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANL 176 VN KGT+FG Q A+ QF +Q G G IVN+VSTAGLQGHP+QSVYNISKGA ANL Sbjct: 122 VNAKGTFFGTQSAVVQFRRQDPNPATGQRGTIVNLVSTAGLQGHPRQSVYNISKGAQANL 181 Query: 177 TRCLAIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLA 236 TRC AIEYG IRVNGICPTYAKT+LTR L++D F + F +++PLKRWGE+ D+A+LA Sbjct: 182 TRCAAIEYGPEGIRVNGICPTYAKTALTRDLYEDMAFMQTFADSVPLKRWGEMADVANLA 241 Query: 237 VFLASDESSYIHGDLIRIDGGETLCRFSV 265 ++LASDESSY+HGDL+RIDGGETLCR+SV Sbjct: 242 LYLASDESSYVHGDLVRIDGGETLCRYSV 270 >ref|ZP_06483182.1| short chain dehydrogenase [Xanthomonas campestris pv. vasculorum NCPPB702] Length = 269 Score = 248 bits (633), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 125/255 (49%), Positives = 168/255 (65%), Gaps = 1/255 (0%) Query: 4 LKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIRETG 63 L KVAI+TGA++G GRGI AFA GA++VV D+ P G F+ P+L+T I E G Sbjct: 5 LDGKVAIVTGATTGIGRGIAVAFARAGAQVVVGDIIRMPRPGSFDERPDLSTADLIAEIG 64 Query: 64 GQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDACFDV 123 G A +V+ DVTR + + A + +GRLDI+VNNAGI GK HEF+ + D DV Sbjct: 65 GSAIFVDYDVTRREAAQAAIEAALASFGRLDIMVNNAGIGIVGKRFHEFSDADFDRTIDV 124 Query: 124 NVKGTWFGCQEAIKQFLKQGDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANLTRCLAIE 183 N+KG WFG QEA K F+ G GG+I+N++STA ++ P Q++YN+SK AAA +TR A+E Sbjct: 125 NIKGMWFGMQEASKHFISAG-GGSIINMLSTAAIRQPPMQAIYNMSKAAAAQMTRSAALE 183 Query: 184 YGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLAVFLASDE 243 YG+ IRVNGICPT KTSLTR L D+ I L R+ EV D+A++A F ASD Sbjct: 184 YGRYNIRVNGICPTMVKTSLTRELTDNAPLMNYIVGTIALGRFAEVSDVANVATFFASDA 243 Query: 244 SSYIHGDLIRIDGGE 258 ++++ G L+ +DG E Sbjct: 244 AAFLSGVLLPVDGAE 258 >ref|ZP_06491423.1| short chain dehydrogenase [Xanthomonas campestris pv. musacearum NCPPB4381] Length = 269 Score = 243 bits (621), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 124/255 (48%), Positives = 166/255 (65%), Gaps = 1/255 (0%) Query: 4 LKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIRETG 63 L KVAI+TGA++G GRGI AFA GA++VV D+ P F+ P+L+T I E G Sbjct: 5 LDGKVAIVTGATTGIGRGIAVAFARAGAQVVVGDIIRMPRPESFDERPDLSTADLIAEIG 64 Query: 64 GQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDACFDV 123 G A +V+ DVTR + + A + +GRLDI+VNNAGI GK HEF+ + D DV Sbjct: 65 GSAIFVDYDVTRREAAQAAIEAALAFFGRLDIMVNNAGIGIVGKRFHEFSDADFDRTIDV 124 Query: 124 NVKGTWFGCQEAIKQFLKQGDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANLTRCLAIE 183 N+KG WFG QEA K F+ G GG+I+N++STA ++ P Q++YN+SK AAA +TR A+E Sbjct: 125 NIKGMWFGMQEAAKHFISAG-GGSIINMLSTAAIRQPPMQAIYNMSKAAAAQMTRSAALE 183 Query: 184 YGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLAVFLASDE 243 YG+ IRVNGICPT KTSLTR L D+ I L R+ EV D+A +A F ASD Sbjct: 184 YGRYNIRVNGICPTMVKTSLTRELTDNAPLMNYIVGTIALGRFAEVSDVAHVATFFASDA 243 Query: 244 SSYIHGDLIRIDGGE 258 ++++ G L+ +DG E Sbjct: 244 AAFLSGVLLPVDGAE 258 >ref|ZP_06483183.1| putative oxidoreductase, short- chain dehydrogenase/reductase [Xanthomonas campestris pv. vasculorum NCPPB702] Length = 266 Score = 211 bits (536), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 114/264 (43%), Positives = 155/264 (58%), Gaps = 5/264 (1%) Query: 1 MTRLKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIR 60 M L KVAI+TGA++G GRGI A A GAKIV+ D+ P G ++ P+LTT I Sbjct: 1 MRALDGKVAIVTGATTGIGRGIAVALAQAGAKIVIGDIIRLPREGSYDERPDLTTAELIA 60 Query: 61 ETGGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDAC 120 E GG A + CDVTR+ V+ V A V +GRLDI+VNNAGI+ + E + E+ + Sbjct: 61 EIGGSATFAECDVTRSTAVSGAVDAAVSLFGRLDIMVNNAGIFTRLETIIEQSEEDYELT 120 Query: 121 FDVNVKGTWFGCQEAIKQFLKQG-----DGGNIVNIVSTAGLQGHPKQSVYNISKGAAAN 175 VN K W GC+ A++Q ++Q G ++NI S AG+ G P + Y SKGA Sbjct: 121 MAVNAKSVWLGCKFALRQMMRQQPLPGRSRGRVINIASAAGVSGLPLEPAYCASKGAVLA 180 Query: 176 LTRCLAIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASL 235 LTR LA+++G + I VN I P +T +TR+ +D + F +A P R G DIA+ Sbjct: 181 LTRQLAVDFGPHGIGVNAIMPGPIQTVMTRSALEDPETAARFRQATPFSRLGTAGDIAAA 240 Query: 236 AVFLASDESSYIHGDLIRIDGGET 259 A FLA DE+ +I+G I IDGG T Sbjct: 241 AAFLAGDEAEFINGAAIAIDGGAT 264 >ref|ZP_06841550.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. Ch1-1] gb|EFG70715.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. Ch1-1] Length = 271 Score = 207 bits (526), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 108/269 (40%), Positives = 159/269 (59%), Gaps = 10/269 (3%) Query: 1 MTR-LKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAI 59 MTR L+ +VA++TG+SSG GR I A A +GA +V SD+ ++ +GG+E + E T A I Sbjct: 1 MTRKLESRVAVVTGSSSGNGRAIALALAREGAHVVCSDLKKSALQGGYEKDIETDTDAVI 60 Query: 60 RETGGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDA 119 GG+ ++ D ++A DV K++ V +GRLDIIVNNAG++ + E+ D Sbjct: 61 TREGGKTTFIAADASKAADVQKIIGHAVSTFGRLDIIVNNAGVFTGLHSIIDETEEQYDF 120 Query: 120 CFDVNVKGTWFGCQEAIKQFLKQGD---------GGNIVNIVSTAGLQGHPKQSVYNISK 170 +VN KG W GC+ AI QF+KQ G IVNI S GL G + Y SK Sbjct: 121 TMNVNAKGVWLGCKYAITQFMKQEPLTTSTGAQVRGRIVNIASIGGLVGLALEPAYCASK 180 Query: 171 GAAANLTRCLAIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVD 230 GA NLTR LA+++ +I VN ICP + T++ R+ ++ D +K+ + P R G D Sbjct: 181 GAVVNLTRELALDFAPERINVNAICPGFLATAMVRSFLENDDTNKLLHDLTPWPRVGTAD 240 Query: 231 DIASLAVFLASDESSYIHGDLIRIDGGET 259 D+A A+FLASD++ ++ G ++ +DG T Sbjct: 241 DVARAALFLASDDAEWMTGSMLTVDGAFT 269 >ref|YP_558148.1| putative oxidoreductase, short- chain dehydrogenase/reductase [Burkholderia xenovorans LB400] gb|ABE30096.1| Putative oxidoreductase, short- chain dehydrogenase/reductase [Burkholderia xenovorans LB400] Length = 271 Score = 206 bits (524), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 109/269 (40%), Positives = 160/269 (59%), Gaps = 10/269 (3%) Query: 1 MTR-LKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAI 59 MTR L+ +VAI+TG+SSG GR I A A +GA +V SD+ ++ +GG+E + E T A I Sbjct: 1 MTRKLEGRVAIVTGSSSGNGRAIALALAREGAHVVCSDLKKSALKGGYEKDIETDTDAVI 60 Query: 60 RETGGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDA 119 + GG+ ++ D ++A DV K+V V +GRLDIIVNNAG++ + E+ D Sbjct: 61 AQQGGKTAFIAADASKAADVQKIVDHAVSTFGRLDIIVNNAGVFTGLHSIIDETEEQYDF 120 Query: 120 CFDVNVKGTWFGCQEAIKQFLKQGD---------GGNIVNIVSTAGLQGHPKQSVYNISK 170 +VN KG W GC+ AI QF+KQ G IVNI S GL G + Y SK Sbjct: 121 TMNVNAKGVWLGCKYAITQFMKQEPLTTSTGVQVRGRIVNIASIGGLVGLALEPAYCASK 180 Query: 171 GAAANLTRCLAIEYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVD 230 GA NLTR LA+++ +I VN ICP + T++ R+ ++ D +K+ + P R G + Sbjct: 181 GAVVNLTRELALDFAPERINVNAICPGFLATAMVRSFLENDDTNKLLHDLTPWPRVGTAE 240 Query: 231 DIASLAVFLASDESSYIHGDLIRIDGGET 259 D+A A+FLASD++ ++ G ++ +DG T Sbjct: 241 DVAKAALFLASDDAEWMTGSMLTVDGAFT 269 >ref|YP_002247838.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Coprothermobacter proteolyticus DSM 5265] gb|ACI17588.1| 3-oxoacyl-(acyl-carrier-protein) reductase [Coprothermobacter proteolyticus DSM 5265] Length = 253 Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 110/255 (43%), Positives = 145/255 (56%), Gaps = 9/255 (3%) Query: 3 RLKDKVAIITGASSGFGRGIGFAFANQGAKIVVSDVHEAPNRGGFEGNPELTTTAAIRET 62 +L KV +ITGA SG GR FA +GAK+V D + G T + E Sbjct: 4 KLYGKVVVITGAGSGMGRAASIIFAQEGAKVVAVD---------YVGETAEETVRMVNEK 54 Query: 63 GGQAYYVNCDVTRADDVAKLVAATVERYGRLDIIVNNAGIYRAGKLAHEFAVEELDACFD 122 GG+A V DV+ DDV K V A VE YG+LDI+VNNAG++ K E + + Sbjct: 55 GGEAIAVKADVSHWDDVNKAVEAAVEHYGKLDIMVNNAGVFDGFKPCLESDEALWERIIN 114 Query: 123 VNVKGTWFGCQEAIKQFLKQGDGGNIVNIVSTAGLQGHPKQSVYNISKGAAANLTRCLAI 182 +N+KG ++GC+ AI+QFL QG+GG IVN S AGL + Y SK LT+ +A Sbjct: 115 INLKGVFYGCKRAIQQFLSQGNGGVIVNTASVAGLGAMAGGTAYTASKHGVVGLTKQIAC 174 Query: 183 EYGQNKIRVNGICPTYAKTSLTRALFDDKDFDKVFTEAIPLKRWGEVDDIASLAVFLASD 242 EY IRVN +CP T +TR L D D++ + PL RWGE ++IA +FLASD Sbjct: 175 EYASQGIRVNAVCPGGIVTGMTRDLMSDPQTDQLIKQTTPLGRWGEPEEIAEAILFLASD 234 Query: 243 ESSYIHGDLIRIDGG 257 SSYI G+ +R+DGG Sbjct: 235 ASSYITGEALRVDGG 249