BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0133.p (260 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08867755.1| short-chained dehydrogenase [Azospirillum ama... 292 4e-77 ref|YP_003487127.1| hypothetical protein SCAB_14061 [Streptomyce... 242 4e-62 ref|YP_003487110.1| short chain dehydrogenase/reductase [Strepto... 239 4e-61 ref|ZP_05227169.1| 3-oxoacyl-ACP reductase [Mycobacterium intrac... 237 1e-60 ref|YP_004522369.1| short-chain dehydrogenase [Mycobacterium sp.... 184 8e-45 ref|ZP_06847670.1| short chain dehydrogenase/reductase family ox... 178 8e-43 ref|ZP_06851023.1| 3-oxoacyl-[acyl-carrier-protein] reductase [M... 176 3e-42 ref|YP_119600.1| putative short chain dehydrogenase [Nocardia fa... 175 5e-42 ref|YP_003487120.1| hypothetical protein SCAB_13981 [Streptomyce... 174 8e-42 ref|YP_708185.1| short-chained dehydrogenase [Rhodococcus jostii... 171 7e-41 >ref|ZP_08867755.1| short-chained dehydrogenase [Azospirillum amazonense Y2] gb|EGY02659.1| short-chained dehydrogenase [Azospirillum amazonense Y2] Length = 311 Score = 292 bits (747), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 139/254 (54%), Positives = 184/254 (72%) Query: 4 ARADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFE 63 +RA+AV EIC GG AVADT++VAT EGA A+VQTALDA+G+VD LVNNAGV+E+ LFE Sbjct: 56 SRAEAVAAEICAAGGIAVADTNTVATREGAQAVVQTALDAFGRVDGLVNNAGVLEYTLFE 115 Query: 64 ELSATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGG 123 +L+ DI K++ +H+MGTIWMCR+VWPHM AG GRIVNTVSGS++GA+Y++VYGASK Sbjct: 116 KLTTADIEKMVASHVMGTIWMCRSVWPHMAAAGKGRIVNTVSGSVIGAKYSTVYGASKAA 175 Query: 124 IMGLTRNLAIEGADIGVKVNALAPGAATVAWTTMSAEQAKPSPEILAKLSPDFVSPTVGA 183 I GLTRNLAIE ++G+KVN++ P AATVAW T S ++ +P +L + SPD V+P + Sbjct: 176 IFGLTRNLAIEAEELGIKVNSILPSAATVAWLTFSDDETRPDKHVLQEHSPDHVAPALAF 235 Query: 184 LAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLDRAGQREIGDP 243 L H + P +G+CIG G NV+E+ R+ G T + + ++ RA +GDP Sbjct: 236 LMHETVPCNGRCIGMNGTNVYEVGLWRSRGVTGTDWTPEKIRERLAEISGRANVEILGDP 295 Query: 244 FDGCAGFKLTPRSY 257 FDG AG+ L PR Y Sbjct: 296 FDGQAGYTLRPRDY 309 >ref|YP_003487127.1| hypothetical protein SCAB_14061 [Streptomyces scabiei 87.22] emb|CBG68557.1| putative PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE [Streptomyces scabiei 87.22] Length = 282 Score = 242 bits (617), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 129/251 (51%), Positives = 168/251 (66%), Gaps = 4/251 (1%) Query: 4 ARADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFE 63 A + VV+EI +LGG AV DTHSVATE+GA A+V TALDAYG+VD L+NNAGV+ FA F Sbjct: 16 AHPETVVQEIRDLGGTAVVDTHSVATEDGALAVVATALDAYGRVDALINNAGVMRFAQFL 75 Query: 64 ELSATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGG 123 EL +I +++D HL GTIWMCRAVWPH+ + G GRI+NT SG++LGA Y SVYGA K G Sbjct: 76 ELQPDEITRMIDVHLYGTIWMCRAVWPHLLRNGGGRILNTTSGAMLGAGYGSVYGAVKSG 135 Query: 124 IMGLTRNLAIEGADIGVKVNALAPGAATVAWTTMSAEQAKPSPEILAKLSPDFVSPTVGA 183 I GLTR LA EGA G+ VN L+PGA T+ + A+ SPE++ + SPD V+P Sbjct: 136 IWGLTRTLAFEGAQDGIAVNTLSPGALTM--SARLADIPPLSPEVIERRSPDRVAPIAAY 193 Query: 184 LAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLDRAGQREIGDP 243 L H CPASGK + +E G++ E+ Y +T G V W+ V+DR +++ DP Sbjct: 194 LVHPDCPASGKNVVAEEGHLHEVLYRQTDGVRLTAPSVDEVADAWESVVDRTAAQDLADP 253 Query: 244 FDGCAGFKLTP 254 + +GF L P Sbjct: 254 PE--SGFWLGP 262 >ref|YP_003487110.1| short chain dehydrogenase/reductase [Streptomyces scabiei 87.22] emb|CBG68540.1| PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE [Streptomyces scabiei 87.22] Length = 315 Score = 239 bits (609), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 122/245 (49%), Positives = 163/245 (66%), Gaps = 7/245 (2%) Query: 4 ARADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFE 63 A A+ + EI GG+A+ADTHSVATE+GA +V TALDA+G+VD+L+NNAGV F+ Sbjct: 58 ASAETIAAEIRAEGGEAIADTHSVATEDGAKGVVGTALDAWGRVDVLINNAGVFRVGEFD 117 Query: 64 ELSATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGG 123 L + I ++D HLMGTIWMCRAVWPHM++AGYGRIVNT SG++ GA Y+SVYGA+K G Sbjct: 118 RLPSDAISALVDVHLMGTIWMCRAVWPHMREAGYGRIVNTTSGAMTGAGYSSVYGAAKAG 177 Query: 124 IMGLTRNLAIEGADIGVKVNALAPGAAT-----VAWTTMSAEQAKPSPEILAKLSPDFVS 178 + LTR LA+EG G+ VNALAPGAAT E P+P + +P+ V+ Sbjct: 178 VWSLTRTLALEGHRHGIVVNALAPGAATGSVRVAPGIPAPPETGHPAPPEIG--TPEMVA 235 Query: 179 PTVGALAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLDRAGQR 238 P LAH SCP SG I SE G V+E ++ +T G+ + + ++ +W +V+DR R Sbjct: 236 PAAAYLAHESCPCSGAGIHSESGRVWESYFAQTEGWGNPGMTVEDLAAHWHRVVDRKQSR 295 Query: 239 EIGDP 243 + GDP Sbjct: 296 DYGDP 300 >ref|ZP_05227169.1| 3-oxoacyl-ACP reductase [Mycobacterium intracellulare ATCC 13950] Length = 319 Score = 237 bits (605), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 129/271 (47%), Positives = 164/271 (60%), Gaps = 20/271 (7%) Query: 4 ARADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFE 63 A A+ V EIC GG+AVAD HSVA E+GA +VQTA+D +G+VDILVNNAGV A F+ Sbjct: 55 ANAEQVADEICAAGGEAVADLHSVADEDGARRVVQTAMDVWGRVDILVNNAGVCFMAHFD 114 Query: 64 ELSATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGG 123 E+S DI ++D HLMGT+WMCRA WPHM+ AGYGRIVNT SG++ G S+YGA+KGG Sbjct: 115 EISDADIRNVIDVHLMGTVWMCRAAWPHMRDAGYGRIVNTTSGAMFGLENLSIYGAAKGG 174 Query: 124 IMGLTRNLAIEGADIGVKVNALAPGAATVAWTTMSAEQAKPSPEILAKLSPD-----FVS 178 I GLTR LA+EGA +G+KVNAL P A T A + +P +L D VS Sbjct: 175 IFGLTRGLAVEGAPLGIKVNALGPAANTTAVRHFN------NPSAFTRLMEDHFPTGLVS 228 Query: 179 PTVGALAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLDRAGQR 238 P V L H SCP SG + + GGNV +G+T G D +L V + + D + R Sbjct: 229 PAVAFLVHESCPVSGANLEAGGGNVGIRVFGQTTGIYDADLTIEKVRDTFAAITDTSTAR 288 Query: 239 EIGDPFDG---------CAGFKLTPRSYRPS 260 I D D A ++ P+ Y+PS Sbjct: 289 LIPDLPDSGQLAPGEAISAPIEVLPKRYQPS 319 >ref|YP_004522369.1| short-chain dehydrogenase [Mycobacterium sp. JDM601] gb|AEF35115.1| short-chain type dehydrogenase/reductase [Mycobacterium sp. JDM601] Length = 303 Score = 184 bits (468), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 101/236 (42%), Positives = 143/236 (60%), Gaps = 8/236 (3%) Query: 6 ADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFEEL 65 AD VVREI E GG+AVA SVA E A I+ TA++ +G++D++VNNAG+ + LF EL Sbjct: 54 ADEVVREISESGGRAVACYASVAEPEDAQTIIDTAIETFGRIDVVVNNAGIHDPGLFTEL 113 Query: 66 SATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGA-RYASVYGASKGGI 124 S ++LD H +GT+ +CRA WPH AGYGR+VNTVS ++LG + YGA+KG + Sbjct: 114 SVEQFRRMLDVHYLGTVAVCRAAWPHFVAAGYGRVVNTVSEAMLGGISELTSYGAAKGAV 173 Query: 125 MGLTRNLAIEGADIGVKVNALAPGAATVAWTTMS---AEQAKPSPEIL----AKLSPDFV 177 GLTRNLA EG G++VNA+AP A T + S A Q +++ A + P+ Sbjct: 174 FGLTRNLATEGIRHGIRVNAVAPRANTRMSASHSDSVAAQLSIPKDVMNTINASMPPELC 233 Query: 178 SPTVGALAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLD 233 +P LAH CP +G+ + G V L RTAG T L + ++ N +Q+++ Sbjct: 234 APAAAFLAHEDCPLNGEVLQIGMGGVARLAVVRTAGITKSPLSAEDIAENLEQIMN 289 >ref|ZP_06847670.1| short chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] gb|EFG78986.1| short chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length = 319 Score = 178 bits (451), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 106/253 (41%), Positives = 145/253 (57%), Gaps = 13/253 (5%) Query: 6 ADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFEEL 65 A+AV EI GG+AVAD HSVA+ +G AI+ TAL +G+VDIL+NNAG+V A FE++ Sbjct: 55 ANAVSEEIRGQGGEAVADMHSVASPQGGEAIIDTALRTWGRVDILINNAGIVGDAPFEDM 114 Query: 66 SATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGS-LLGARYASVYGASKGGI 124 + +LD HL G + R W M++ YGR++NT S + +LGA S YGA+K G+ Sbjct: 115 TPERFEPLLDVHLRGAFHVMRPAWRIMREQRYGRVLNTCSAAGILGAERMSNYGAAKTGL 174 Query: 125 MGLTRNLAIEGADIGVKVNALAPGAAT-VAWTTMSAEQAKPSP-----------EILAKL 172 +GLTR LA EGA+ GVKVNA+AP A T + +++A + P + L KL Sbjct: 175 LGLTRVLAAEGAERGVKVNAIAPIAHTRMLAQSLAAAGRRDDPAEQAVLDGLVGQYLQKL 234 Query: 173 SPDFVSPTVGALAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVL 232 P V+P L H CP SG+ G+V + GRT G+ D L V + D++ Sbjct: 235 DPARVAPVAAFLTHRDCPVSGEVYTVGAGHVARFFVGRTRGFYDPLLSIEKVRDHLDEIR 294 Query: 233 DRAGQREIGDPFD 245 D AG G P D Sbjct: 295 DEAGYTVPGGPAD 307 >ref|ZP_06851023.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Mycobacterium parascrofulaceum ATCC BAA-614] gb|EFG75642.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length = 297 Score = 176 bits (446), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 102/232 (43%), Positives = 137/232 (59%), Gaps = 8/232 (3%) Query: 6 ADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFEEL 65 A+AV +EI GG AVAD HSVAT EG AIVQ ALDA+G+VDI+VNNAG++ F L Sbjct: 54 AEAVAQEIEAAGGIAVADGHSVATREGGAAIVQAALDAFGRVDIVVNNAGILRDKSFHNL 113 Query: 66 SATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGS-LLGARYASVYGASKGGI 124 + + ++D HL GTIW+ + + M++ GYGRIVNT S + + G + YGA+K G+ Sbjct: 114 TPELLDPVIDVHLYGTIWVTQPAFLRMREQGYGRIVNTSSAAGIFGNFGQTNYGAAKMGV 173 Query: 125 MGLTRNLAIEGADIGVKVNALAPGAATVAWTTMSAEQAKPSPEILAKLSPDFVSPTVGAL 184 +G TR LA EGA +KVNA+AP +A T M+ E P I KL P V+P V L Sbjct: 174 IGFTRVLAQEGAKYNIKVNAIAP----MARTRMTEELLGP---IAKKLDPALVAPVVAYL 226 Query: 185 AHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLDRAG 236 H SC + + GG V E++ T G++ L V N + + DR G Sbjct: 227 CHESCDLTSRIFSVGGGRVAEIFISVTKGFSSPTLDIEAVQDNLEAICDREG 278 >ref|YP_119600.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152] dbj|BAD58236.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152] Length = 301 Score = 175 bits (444), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 98/231 (42%), Positives = 136/231 (58%), Gaps = 7/231 (3%) Query: 6 ADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFEEL 65 A AVV EI GG AVA VATEEGA ++V A+ ++G++D LVNNAG+V A F E+ Sbjct: 55 AAAVVAEITAAGGTAVACHADVATEEGARSLVDAAVSSFGRIDALVNNAGIVRAAPFREV 114 Query: 66 SATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGGIM 125 + + LD H +G + +CRA WPH+ +A R+VNT+S ++LG S YG SKG + Sbjct: 115 PDEEYQRHLDVHYLGPMRLCRAAWPHLLEAEAPRVVNTISQAMLGNPGMSHYGGSKGALF 174 Query: 126 GLTRNLAIEGADIGVKVNALAPGAATVAWTTMSAEQAKPSPEILAKLS----PDFVSPTV 181 GLTRNLA+EG + G+KVNA+APGA+T + A +PEI+A + P+ ++P V Sbjct: 175 GLTRNLALEGLEAGIKVNAIAPGAST---RMLEAAADTLTPEIMAYMRSSMLPEHIAPVV 231 Query: 182 GALAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVL 232 L H C +G+ GG V L T G D L V +DQ++ Sbjct: 232 AYLVHPDCQVTGEVFNVAGGIVNRLALVNTVGIHDPALTVEAVAEQFDQIM 282 >ref|YP_003487120.1| hypothetical protein SCAB_13981 [Streptomyces scabiei 87.22] emb|CBG68550.1| putative PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE [Streptomyces scabiei 87.22] Length = 193 Score = 174 bits (442), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 89/173 (51%), Positives = 116/173 (67%), Gaps = 3/173 (1%) Query: 73 ILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGGIMGLTRNLA 132 ++D HL+GTIWMCRAVWPHM+ AGYGRIVNT S +LG+ Y SVYGA K G GLTR+LA Sbjct: 1 MVDVHLLGTIWMCRAVWPHMRDAGYGRIVNTTSPGMLGSGYGSVYGAVKAGSYGLTRSLA 60 Query: 133 IEGADIGVKVNALAPGAATVAWTTMSA--EQAKPSPEILAKLSPDFVSPTVGALAHVSCP 190 IEG G++ NALAP AAT+AW + A ++A P + +SPD ++PT LAH CP Sbjct: 61 IEGDPFGIRANALAPLAATIAWDVVQAPGKEAMDGP-VAQDMSPDLIAPTAALLAHRVCP 119 Query: 191 ASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVLDRAGQREIGDP 243 SGK I ++ G V E +Y +TAGY ++ + QV+DR+ +IGDP Sbjct: 120 FSGKNITADPGRVSETYYRQTAGYAKVAPTIEELNDSLRQVVDRSDAHDIGDP 172 >ref|YP_708185.1| short-chained dehydrogenase [Rhodococcus jostii RHA1] gb|ABH00027.1| probable short-chained dehydrogenase [Rhodococcus jostii RHA1] Length = 301 Score = 171 bits (434), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 96/231 (41%), Positives = 134/231 (58%), Gaps = 7/231 (3%) Query: 6 ADAVVREICELGGQAVADTHSVATEEGANAIVQTALDAYGKVDILVNNAGVVEFALFEEL 65 A AVV EI GG+A+A V+TE GA ++V+ A+D +G +D +VNNAG+V A F E+ Sbjct: 55 AAAVVAEITAAGGRAIACGADVSTEAGAQSLVEAAVDGFGHLDAVVNNAGIVRTARFLEV 114 Query: 66 SATDIHKILDTHLMGTIWMCRAVWPHMKQAGYGRIVNTVSGSLLGARYASVYGASKGGIM 125 + + +D H GT+ +CRA WPH+ +G GR+VNT+S ++LG + YG+SKG + Sbjct: 115 PDDEYQRHIDVHYFGTLRVCRAAWPHLAASGSGRVVNTLSAAMLGNPMMTHYGSSKGAVF 174 Query: 126 GLTRNLAIEGADIGVKVNALAPGAATVAWTTMSAEQAKPSPEIL----AKLSPDFVSPTV 181 GLTRNLAIEG + G+KVNA+APGA T A SPEI+ L + V+P Sbjct: 175 GLTRNLAIEGLEAGIKVNAVAPGAGT---RMAEASSEGLSPEIMDYIRTSLRAELVAPVA 231 Query: 182 GALAHVSCPASGKCIGSEGGNVFELWYGRTAGYTDHELQSHNVHLNWDQVL 232 L H S +G+ GG V L T G TD L +V D+++ Sbjct: 232 TYLVHPSATMTGEVFNVAGGTVNRLALLNTVGITDPNLSVESVASRIDEIM 282