BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0102.p (459 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774878.1| dihydrolipoamide acetyltransferase component... 150 4e-34 ref|YP_001099068.1| dihydrolipoyllysine-residue acetyltransferas... 140 7e-31 ref|YP_001352364.1| pyruvate dehydrogenase E2 component (dihydro... 139 1e-30 ref|YP_004754203.1| dihydrolipoamide dehydrogenase of pyruvate d... 137 3e-30 ref|YP_001099069.1| dihydrolipoyl dehydrogenase (E3 component of... 135 1e-29 ref|YP_001352366.1| dihydrolipoamide dehydrogenase [Janthinobact... 133 6e-29 ref|YP_004754205.1| dihydrolipoamide acetyltransferase component... 131 3e-28 ref|ZP_07045622.1| pyruvate dehydrogenase complex dihydrolipoami... 127 5e-27 ref|YP_003278290.1| pyruvate dehydrogenase complex dihydrolipoam... 127 5e-27 ref|ZP_03543298.1| pyruvate dehydrogenase complex dihydrolipoami... 127 6e-27 >ref|YP_003774878.1| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex [Herbaspirillum seropedicae SmR1] gb|ADJ62970.1| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2) protein [Herbaspirillum seropedicae SmR1] Length = 554 Score = 150 bits (380), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 69/70 (98%), Positives = 69/70 (98%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK Sbjct: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 Query: 61 VKVGDKVAEA 70 VKVGDKVAE Sbjct: 61 VKVGDKVAEG 70 Score = 125 bits (313), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 54/67 (80%), Positives = 64/67 (95%) Query: 4 VEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIKVKV 63 VE++VPDIGDFKEVEVIEVMVKVGDT+K +QSL+TVESDKASMEIPSS AGV+KE+KVK+ Sbjct: 120 VEIEVPDIGDFKEVEVIEVMVKVGDTVKAEQSLLTVESDKASMEIPSSHAGVIKELKVKL 179 Query: 64 GDKVAEA 70 GDKV++ Sbjct: 180 GDKVSKG 186 >ref|YP_001099068.1| dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2) (dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) [Herminiimonas arsenicoxydans] emb|CAL60941.1| Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) [Herminiimonas arsenicoxydans] Length = 455 Score = 140 bits (352), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 62/70 (88%), Positives = 67/70 (95%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 MS VEVKVPDIGDFKEVE+IE++VKVGDTIK+DQSLITVESDKASMEIPSS AGVVKEIK Sbjct: 1 MSTVEVKVPDIGDFKEVEIIELLVKVGDTIKIDQSLITVESDKASMEIPSSHAGVVKEIK 60 Query: 61 VKVGDKVAEA 70 VK+GDKVAE Sbjct: 61 VKLGDKVAEG 70 >ref|YP_001352364.1| pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Janthinobacterium sp. Marseille] gb|ABR88599.1| pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Janthinobacterium sp. Marseille] Length = 458 Score = 139 bits (349), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 62/70 (88%), Positives = 66/70 (94%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 MS VEVKVPDIGDFKEVEVIE++VK GDTIKVDQSLITVESDKASMEIPSS AGVVKEIK Sbjct: 1 MSMVEVKVPDIGDFKEVEVIELLVKAGDTIKVDQSLITVESDKASMEIPSSHAGVVKEIK 60 Query: 61 VKVGDKVAEA 70 VK+GDK+AE Sbjct: 61 VKLGDKIAEG 70 >ref|YP_004754203.1| dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [Collimonas fungivorans Ter331] gb|AEK63380.1| Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex [Collimonas fungivorans Ter331] Length = 698 Score = 137 bits (346), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 63/70 (90%), Positives = 67/70 (95%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 MS VEVKVPDIGD KEVEVIE+MVKVGDT+KVDQSLITVESDKASMEIPSSQAGV+KEIK Sbjct: 1 MSMVEVKVPDIGDVKEVEVIELMVKVGDTVKVDQSLITVESDKASMEIPSSQAGVIKEIK 60 Query: 61 VKVGDKVAEA 70 VKVGDKV+E Sbjct: 61 VKVGDKVSEG 70 Score = 129 bits (323), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 57/69 (82%), Positives = 66/69 (95%) Query: 2 SQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIKV 61 S +E+KVPDIGD KEV+VIE+MVKVGD++KVDQSLITVESDKASMEIPSSQAGV+KE+KV Sbjct: 112 STIEIKVPDIGDVKEVDVIELMVKVGDSVKVDQSLITVESDKASMEIPSSQAGVIKEVKV 171 Query: 62 KVGDKVAEA 70 KVGDKV+E Sbjct: 172 KVGDKVSEG 180 >ref|YP_001099069.1| dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (dihydrolipoamide dehydrogenase) [Herminiimonas arsenicoxydans] emb|CAL60942.1| Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) [Herminiimonas arsenicoxydans] Length = 611 Score = 135 bits (341), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 60/70 (85%), Positives = 66/70 (94%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 MS +EVKVPDIGDFKEVE+IE++V VGDTIKVDQSLITVESDKASMEIPSS AGVVKE+K Sbjct: 1 MSTIEVKVPDIGDFKEVEIIEMLVNVGDTIKVDQSLITVESDKASMEIPSSHAGVVKELK 60 Query: 61 VKVGDKVAEA 70 VK+GDKVAE Sbjct: 61 VKLGDKVAEG 70 >ref|YP_001352366.1| dihydrolipoamide dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR88378.1| dihydrolipoamide dehydrogenase [Janthinobacterium sp. Marseille] Length = 603 Score = 133 bits (335), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 56/67 (83%), Positives = 65/67 (97%) Query: 4 VEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIKVKV 63 +EVKVPDIGDFKEVE+IE++VKVGDTIK+DQSLITVESDKASMEIPSS AGV+KE+K+K+ Sbjct: 2 IEVKVPDIGDFKEVEIIELLVKVGDTIKIDQSLITVESDKASMEIPSSHAGVIKELKIKL 61 Query: 64 GDKVAEA 70 GDKVAE Sbjct: 62 GDKVAEG 68 >ref|YP_004754205.1| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex [Collimonas fungivorans Ter331] gb|AEK63382.1| Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex [Collimonas fungivorans Ter331] Length = 442 Score = 131 bits (329), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 59/70 (84%), Positives = 64/70 (91%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 MS VEVKVPDIGD EVEVIE+MVKVGDT+KVDQSLITVESDKASMEIPSS AGV+KE+K Sbjct: 1 MSMVEVKVPDIGDVSEVEVIELMVKVGDTVKVDQSLITVESDKASMEIPSSHAGVIKELK 60 Query: 61 VKVGDKVAEA 70 VK+GDKV E Sbjct: 61 VKLGDKVKEG 70 >ref|ZP_07045622.1| pyruvate dehydrogenase complex dihydrolipoamide [Comamonas testosteroni S44] gb|EFI60853.1| pyruvate dehydrogenase complex dihydrolipoamide [Comamonas testosteroni S44] Length = 563 Score = 127 bits (318), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 58/70 (82%), Positives = 63/70 (90%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 M+ E+KVPDIGDF EV VIEV+VKVGDTIKV+QSLITVESDKASMEIPSSQAGVVKEIK Sbjct: 1 MALTEIKVPDIGDFSEVGVIEVLVKVGDTIKVEQSLITVESDKASMEIPSSQAGVVKEIK 60 Query: 61 VKVGDKVAEA 70 V +GDKV E Sbjct: 61 VALGDKVKEG 70 Score = 93.6 bits (231), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 42/66 (63%), Positives = 54/66 (81%) Query: 2 SQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIKV 61 S V++K+PDIGDFK+V VIE++VKVGDT+ +QSL TVESDKASMEIPS AG + + + Sbjct: 117 STVDLKIPDIGDFKDVAVIEMLVKVGDTVTAEQSLFTVESDKASMEIPSPSAGTITALTI 176 Query: 62 KVGDKV 67 K+GD V Sbjct: 177 KLGDTV 182 >ref|YP_003278290.1| pyruvate dehydrogenase complex dihydrolipoamide [Comamonas testosteroni CNB-2] gb|ACY32994.1| pyruvate dehydrogenase complex dihydrolipoamide [Comamonas testosteroni CNB-2] Length = 563 Score = 127 bits (318), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 58/70 (82%), Positives = 63/70 (90%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 M+ E+KVPDIGDF EV VIEV+VKVGDTIKV+QSLITVESDKASMEIPSSQAGVVKEIK Sbjct: 1 MALTEIKVPDIGDFSEVGVIEVLVKVGDTIKVEQSLITVESDKASMEIPSSQAGVVKEIK 60 Query: 61 VKVGDKVAEA 70 V +GDKV E Sbjct: 61 VALGDKVKEG 70 Score = 93.6 bits (231), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 42/66 (63%), Positives = 54/66 (81%) Query: 2 SQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIKV 61 S V++K+PDIGDFK+V VIE++VKVGDT+ +QSL TVESDKASMEIPS AG + + + Sbjct: 117 STVDLKIPDIGDFKDVAVIEMLVKVGDTVTAEQSLFTVESDKASMEIPSPSAGTITALTI 176 Query: 62 KVGDKV 67 K+GD V Sbjct: 177 KLGDTV 182 >ref|ZP_03543298.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase [Comamonas testosteroni KF-1] gb|EED67584.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase [Comamonas testosteroni KF-1] Length = 561 Score = 127 bits (318), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 58/70 (82%), Positives = 63/70 (90%) Query: 1 MSQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIK 60 M+ E+KVPDIGDF EV VIEV+VKVGDTIKV+QSLITVESDKASMEIPSSQAGVVKEIK Sbjct: 1 MALTEIKVPDIGDFSEVGVIEVLVKVGDTIKVEQSLITVESDKASMEIPSSQAGVVKEIK 60 Query: 61 VKVGDKVAEA 70 V +GDKV E Sbjct: 61 VALGDKVKEG 70 Score = 96.3 bits (238), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 43/66 (65%), Positives = 55/66 (83%) Query: 2 SQVEVKVPDIGDFKEVEVIEVMVKVGDTIKVDQSLITVESDKASMEIPSSQAGVVKEIKV 61 S V++K+PDIGDFK+V VIE++VKVGDT+ V+QSL TVESDKASMEIPS AG + + + Sbjct: 118 STVDLKIPDIGDFKDVAVIEMLVKVGDTVAVEQSLFTVESDKASMEIPSPSAGTITALTI 177 Query: 62 KVGDKV 67 K+GD V Sbjct: 178 KLGDTV 183