BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0022.p (706 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774281.1| transmembrane protein [Herbaspirillum serope... 1410 0.0 ref|YP_001889600.1| diguanylate cyclase/phosphodiesterase [Burkh... 582 e-164 ref|ZP_02883916.1| diguanylate cyclase/phosphodiesterase [Burkho... 575 e-162 ref|ZP_06840776.1| diguanylate cyclase/phosphodiesterase with MH... 573 e-161 ref|YP_553234.1| diguanylate cyclase/phosphodiesterase [Burkhold... 572 e-161 ref|YP_004231733.1| diguanylate cyclase/phosphodiesterase with M... 572 e-160 ref|YP_003909357.1| diguanylate cyclase/phosphodiesterase with M... 571 e-160 ref|YP_001860890.1| diguanylate cyclase/phosphodiesterase [Burkh... 570 e-160 ref|YP_003607041.1| diguanylate cyclase/phosphodiesterase with M... 566 e-159 ref|ZP_03265056.1| diguanylate cyclase/phosphodiesterase [Burkho... 565 e-158 >ref|YP_003774281.1| transmembrane protein [Herbaspirillum seropedicae SmR1] gb|ADJ62373.1| transmembrane protein [Herbaspirillum seropedicae SmR1] Length = 706 Score = 1410 bits (3651), Expect = 0.0, Method: Compositional matrix adjust. Identities = 705/706 (99%), Positives = 705/706 (99%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQHRRLWLSVGAVVLGLGVWATLFL 60 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQHRRLWLSVGAVVLGLGVWATLFL Sbjct: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQHRRLWLSVGAVVLGLGVWATLFL 60 Query: 61 TVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINAA 120 TVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINAA Sbjct: 61 TVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINAA 120 Query: 121 FHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRRV 180 FHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRRV Sbjct: 121 FHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRRV 180 Query: 181 LAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVISG 240 LAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVISG Sbjct: 181 LAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVISG 240 Query: 241 VQRNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLFMD 300 VQRNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLFMD Sbjct: 241 VQRNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLFMD 300 Query: 301 LDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVVEQ 360 LDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVVEQ Sbjct: 301 LDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVVEQ 360 Query: 361 LSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRNTY 420 LSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRNTY Sbjct: 361 LSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRNTY 420 Query: 421 RFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQLG 480 RFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQLG Sbjct: 421 RFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQLG 480 Query: 481 EMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQMRTDLVA 540 EMAP EFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQMRTDLVA Sbjct: 481 EMAPTEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQMRTDLVA 540 Query: 541 RIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSSLAY 600 RIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSSLAY Sbjct: 541 RIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSSLAY 600 Query: 601 LAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRELQL 660 LAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRELQL Sbjct: 601 LAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRELQL 660 Query: 661 LHCDQVQGFLLGRPAEAPSVPGLVQASNDDLFGAAAGASAVLKLER 706 LHCDQVQGFLLGRPAEAPSVPGLVQASNDDLFGAAAGASAVLKLER Sbjct: 661 LHCDQVQGFLLGRPAEAPSVPGLVQASNDDLFGAAAGASAVLKLER 706 >ref|YP_001889600.1| diguanylate cyclase/phosphodiesterase [Burkholderia phytofirmans PsJN] gb|ACD20229.1| diguanylate cyclase/phosphodiesterase [Burkholderia phytofirmans PsJN] Length = 689 Score = 582 bits (1501), Expect = e-164, Method: Compositional matrix adjust. Identities = 313/688 (45%), Positives = 442/688 (64%), Gaps = 8/688 (1%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQH-RRLWLSVGAVVLGLGVWATLF 59 M S++F L+ +++VA+L++Y AL+++ R+ + S R W GA LG+G+W+ F Sbjct: 1 MQSSYNFWLVTISLVVATLASYTALDLTGRIFLLASARLRHAWRLGGAAALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D T +L L +G+++ ++++ L+R P RL GG+ +G I Sbjct: 61 IAMLAFSLPIPLGYDFATTAASLGLAIGASYLALYVTTLQRLTPGRLLAGGVLMGFGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 + +AA+Q+ P + YQ +L + IG AL+ A R +R Sbjct: 121 MHYTGMAALQMAPGIRYQPGWFAASLAIA--IGASTAALWMA---RALSNDGARHVVRKR 175 Query: 180 VLAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVIS 239 + AAL++G+ + + A P A + L ++ L F + + L++S Sbjct: 176 LGAALVMGVAISGMHYTAMAAADFVPGAICGAAKGVNATWLATSVILLTFAILTVTLMLS 235 Query: 240 GVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLF 298 RN +L V R N +++ AT D LTGLPNR+ L DRI+ A+ ARR FA+LF Sbjct: 236 RFDARNALLIGAVSRLNGQIVRLATLDTLTGLPNRSTLTDRIERAILSARRQRTLFAILF 295 Query: 299 MDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVV 358 MDLDGFK INDSLGH+VGD +L A AQR+ QC+R D VAR+GGDEFVV+ NL S + Sbjct: 296 MDLDGFKTINDSLGHSVGDQVLTAFAQRLLQCVRETDTVARLGGDEFVVLAENLGSREDA 355 Query: 359 EQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRN 418 L+E +L +R D L+V SIGIA+YP+ GDSV+ L+K+ADAAMYEAK++GR+ Sbjct: 356 SALAEGVLERMRLGVWTDSQPLQVMPSIGIALYPHDGDSVETLLKHADAAMYEAKRAGRS 415 Query: 419 TYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQ 478 TYRFFE +M+ +A R LQ++ AL A+ F LHFQPK+ G L G EAL+R HPQ Sbjct: 416 TYRFFERSMNEAATRTLQIQNALHDALAAGHFSLHFQPKFHGNGNSLAGAEALIRLHHPQ 475 Query: 479 LGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ-MRTD 537 LG + P EFIPIAERSGQI+ IG WV++ C QI RW + G+ +KVA+NLSP Q ++ + Sbjct: 476 LGALTPLEFIPIAERSGQIVQIGYWVVRETCRQIRRWVSQGLPAMKVAINLSPRQLLQPN 535 Query: 538 LVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSS 597 LVA ++ +V A G+A +++MFEITET AM+D ++ +I E QA GF+IAIDDFGTGYSS Sbjct: 536 LVASMLAIVEAEGVACEQIMFEITETVAMQDAPKTIEMIREFQASGFEIAIDDFGTGYSS 595 Query: 598 LAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRE 657 LAYL +F +Q+KIDRFFT+ LD G AIV+AIIALAH+L+M+VVAEGVETE QL Sbjct: 596 LAYLQRFRVKQLKIDRFFTNGLDAHGPEGSAIVSAIIALAHSLEMDVVAEGVETESQLGM 655 Query: 658 LQLLHCDQVQGFLLGRPAEAPSVPGLVQ 685 L+ + CD++QGFLLG+P A L++ Sbjct: 656 LKTMRCDEMQGFLLGKPLGADDFANLLR 683 >ref|ZP_02883916.1| diguanylate cyclase/phosphodiesterase [Burkholderia graminis C4D1M] gb|EDT10576.1| diguanylate cyclase/phosphodiesterase [Burkholderia graminis C4D1M] Length = 692 Score = 575 bits (1483), Expect = e-162, Method: Compositional matrix adjust. Identities = 313/680 (46%), Positives = 442/680 (65%), Gaps = 14/680 (2%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERM-VMQESQHRRLWLSVGAVVLGLGVWATLF 59 M S++ L+A + +VA+LS+Y AL+++ R+ V+ + R +W GA LG+G+W+ F Sbjct: 1 MQSSYNPWLVAMSFVVATLSSYTALDLTARIFVLASPRLRHVWRMGGAAALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D T +L L +G+++ + L+ R +RL GG +G I Sbjct: 61 VAMLAFSLPIPLGYDFAETAYSLALAIGASYLALCLTTRARLTVARLMGGGAFMGLGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQT-- 177 + +AA+++ PA+ Y+ V +L + IG AL+ A +A S + +Q Sbjct: 121 MHYSGMAALRMSPAISYRPVWFAASLAIA--IGASTAALWMA------RALSNDDEQYVL 172 Query: 178 -RRVLAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALAL 236 +R AA ++ + + A + A AP A A + L ++ F + + L Sbjct: 173 RKRCGAAFVMAIAISGMHYAAMAAADFAPGAICGAAAGVNAAWLATSVILFTFAILVVTL 232 Query: 237 VISGVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFA 295 ++S R L + + N +++ AT D LTGLPNRA L +RI+ A+ ARR FA Sbjct: 233 LLSRFDARTSFLVGALSKLNGQIVRLATLDTLTGLPNRATLTERIERAIYAARRQRSLFA 292 Query: 296 VLFMDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSP 355 +LFMDLDGFK INDSLGH+ GD +L A AQR+ C+R D VAR+GGDEFVV+ NL+S Sbjct: 293 ILFMDLDGFKTINDSLGHSAGDQVLSAFAQRLLVCVRAGDTVARLGGDEFVVLSENLASR 352 Query: 356 DVVEQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQS 415 D L+E +L +R D D L+V SIGIA++P GD+VD L+K+ADAAMYEAK++ Sbjct: 353 DDAATLAEGVLERMRHDTWTDSQPLQVMPSIGIALFPEDGDTVDTLLKHADAAMYEAKRA 412 Query: 416 GRNTYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWT 475 GR+TYRFFE +M+ +AMR LQ++ AL+ A+ E F LHFQPK+ G+S+ L G EAL+R Sbjct: 413 GRSTYRFFERSMNEAAMRTLQIQNALRDALAEHHFTLHFQPKFDGSSESLAGAEALIRLH 472 Query: 476 HPQLGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ-M 534 PQLG +AP EFIPIAERSGQI+ IG WVL+ C QI RW A G+ P+KVA+NLSP Q + Sbjct: 473 DPQLGTLAPLEFIPIAERSGQIVQIGYWVLREACRQIRRWIAQGLPPIKVAINLSPRQLL 532 Query: 535 RTDLVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTG 594 + DLV ++E+V G+ ++MFEITET AM+D R+ ++ E QA GF+IAIDDFGTG Sbjct: 533 QADLVPTMLEIVKTEGVKCDQIMFEITETVAMQDAPRTIDMLREFQASGFEIAIDDFGTG 592 Query: 595 YSSLAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQ 654 YSSLAYL +F +Q+KIDRFFT+ LD G AIV+AIIALAH+L+M+VVAEGVETE Q Sbjct: 593 YSSLAYLQRFRVKQLKIDRFFTNGLDAHGPEGSAIVSAIIALAHSLEMDVVAEGVETESQ 652 Query: 655 LRELQLLHCDQVQGFLLGRP 674 + L+ + CD++QGFLLG+P Sbjct: 653 MHMLKAMRCDEMQGFLLGKP 672 >ref|ZP_06840776.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. Ch1-1] gb|EFG71496.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. Ch1-1] Length = 689 Score = 573 bits (1477), Expect = e-161, Method: Compositional matrix adjust. Identities = 306/688 (44%), Positives = 441/688 (64%), Gaps = 8/688 (1%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQH-RRLWLSVGAVVLGLGVWATLF 59 M S++ L+A + +VA+L++Y AL+++ R+ + S R +W GA LG+G+W+ F Sbjct: 1 MQSSYNLWLVAISFVVATLASYTALDLTGRIFLLASPRLRHVWRLGGAAALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D T +L L + +++ +H++ + SRL GG+ +G I Sbjct: 61 IAMLAFSLPIPLGYDFATTAASLGLAVAASYLALHITTREQLTASRLLAGGVVMGCGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 ++ +AAMQ+ P ++YQ +L + + L A + + +R Sbjct: 121 MHYVGMAAMQMTPGIVYQPAWFAGSLAIAIGASSAALWLARALSDDDAR-----HVVRKR 175 Query: 180 VLAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVIS 239 + +AL +G+ + AG+ A P A + L ++ F + + L++S Sbjct: 176 LASALAMGIAISGMHYAGMAAAGFPPGVVCGAANGVSTTWLATSVILFTFAILIVTLMLS 235 Query: 240 GVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLF 298 R L V N +++ AT D LTGLPNR+ L +RI+HA+ A+R AVLF Sbjct: 236 RFDARTTFLVGAVSNLNGQIVRLATLDSLTGLPNRSTLTERIEHAIHRAQRQRSMCAVLF 295 Query: 299 MDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVV 358 MDLDGFK INDSLGH+VGD +L A AQR+ C+R D VAR+GGDEFVV+ +L S + Sbjct: 296 MDLDGFKTINDSLGHSVGDQVLTAFAQRLLLCVRASDTVARLGGDEFVVLAEDLGSREDA 355 Query: 359 EQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRN 418 L+E +L +R D L+V SIGIA++P+ GD+VD+L+KNADAAMYEAK++GR+ Sbjct: 356 GALAEGVLDRMRMGMWTDSQPLQVMPSIGIALFPHDGDTVDSLLKNADAAMYEAKRAGRS 415 Query: 419 TYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQ 478 TYRFFE +M+ +AMR LQ++ AL A+ QF LHFQPK+ G + L G EAL+R HPQ Sbjct: 416 TYRFFERSMNEAAMRTLQIQNALHDALAAGQFSLHFQPKFHGGGESLAGAEALIRLHHPQ 475 Query: 479 LGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQM-RTD 537 LG++AP EFIPIAERSGQI+ IG WV++ C QI RW + G+ +KVA+NLSP QM + + Sbjct: 476 LGDLAPLEFIPIAERSGQIVQIGYWVVRETCRQIRRWISQGLPSMKVAVNLSPRQMLQPN 535 Query: 538 LVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSS 597 LVA ++E+V A G+ +++MFEITET AM+D ++ +I + QA GF+IAIDDFGTGYSS Sbjct: 536 LVANMLEIVQAEGVQCEQIMFEITETVAMQDAPKTIEMIRQFQACGFEIAIDDFGTGYSS 595 Query: 598 LAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRE 657 LAYL +F +Q+KIDRFFT+ LD G AIV+AIIALAH+L+M+VVAEGVETE QL Sbjct: 596 LAYLQRFRVKQLKIDRFFTNGLDVHGPEGSAIVSAIIALAHSLEMDVVAEGVETESQLDM 655 Query: 658 LQLLHCDQVQGFLLGRPAEAPSVPGLVQ 685 L+ + CD++QGFLLG+P A L++ Sbjct: 656 LRTMMCDEMQGFLLGKPLNADDFGNLLR 683 >ref|YP_553234.1| diguanylate cyclase/phosphodiesterase [Burkholderia xenovorans LB400] gb|ABE33884.1| diguanylate cyclase/phosphodiesterase [Burkholderia xenovorans LB400] Length = 689 Score = 572 bits (1475), Expect = e-161, Method: Compositional matrix adjust. Identities = 305/688 (44%), Positives = 440/688 (63%), Gaps = 8/688 (1%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQH-RRLWLSVGAVVLGLGVWATLF 59 M S++ L+ + +VA+L++Y AL+++ R+ + S R +W GA LG+G+W+ F Sbjct: 1 MQSSYNLWLVVISFVVATLASYTALDLTGRIFLLASPRLRHVWRLGGAAALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D T +L L + +++ +H++ + +RL GG +G I Sbjct: 61 IAMLAFSLPIPLGYDFATTAASLGLAIAASYLALHITTREKLTATRLLAGGAVMGCGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 ++ +AAMQ+ P ++YQ +L + + L A + + +R Sbjct: 121 MHYVGMAAMQMTPGIVYQPAWFAGSLAIAIGASSAALWLARALSDDDAR-----HVVRKR 175 Query: 180 VLAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVIS 239 + AAL++G+ + AG+ A +P A + L ++ F + + L++S Sbjct: 176 LAAALVMGVAISGMHYAGMAAAGFSPGAVCGAANGVNTTWLATSVILFTFAILIVTLILS 235 Query: 240 GVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLF 298 R L V N +++ AT D LTGLPNRA L +RI+HA+ A+R AVLF Sbjct: 236 RFDARTTFLVGAVSNLNGQIVRLATLDSLTGLPNRATLTERIEHAIHRAQRQRSLCAVLF 295 Query: 299 MDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVV 358 MDLDGFK INDSLGH+ GD +L A AQR+ C+R D VAR+GGDEFVV+ +L S + Sbjct: 296 MDLDGFKTINDSLGHSAGDQVLTAFAQRLLLCVRASDTVARLGGDEFVVLAEDLGSREDA 355 Query: 359 EQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRN 418 L+E +L +R D L+V SIGIA++P+ GD+VD+L+KNADAAMYEAK++GR+ Sbjct: 356 GALAEGVLERMRMGMWTDSQPLQVMPSIGIALFPHDGDTVDSLLKNADAAMYEAKRAGRS 415 Query: 419 TYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQ 478 TYRFFE +M+ +AMR LQ++ AL A+ QF LHFQPK+ G + L G EAL+R HPQ Sbjct: 416 TYRFFERSMNEAAMRTLQIQNALHDALAAGQFSLHFQPKFHGGGESLAGAEALIRLHHPQ 475 Query: 479 LGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQM-RTD 537 LG++AP EFIPIAERSGQI+ IG WV++ C QI RW + G+ +KVA+NLSP QM + + Sbjct: 476 LGDLAPLEFIPIAERSGQIVQIGYWVVRETCRQIRRWISQGLPSMKVAVNLSPRQMLQPN 535 Query: 538 LVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSS 597 LVA ++E+V A G+ +++MFEITET AM+D ++ +I + QA GF+IAIDDFGTGYSS Sbjct: 536 LVASMLEIVQAEGVQCEQIMFEITETVAMQDAPKTIEMIRQFQACGFEIAIDDFGTGYSS 595 Query: 598 LAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRE 657 LAYL +F +Q+KIDRFFT+ LD G AIV+AIIALAH+L+M+VVAEGVETE QL Sbjct: 596 LAYLQRFRVKQLKIDRFFTNGLDVHGPEGSAIVSAIIALAHSLEMDVVAEGVETESQLDM 655 Query: 658 LQLLHCDQVQGFLLGRPAEAPSVPGLVQ 685 L+ + CD++QGFLLG+P A L++ Sbjct: 656 LRTMMCDEMQGFLLGKPLSADDFGNLLR 683 >ref|YP_004231733.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. CCGE1001] gb|ADX58673.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. CCGE1001] Length = 692 Score = 572 bits (1473), Expect = e-160, Method: Compositional matrix adjust. Identities = 309/693 (44%), Positives = 444/693 (64%), Gaps = 18/693 (2%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERM-VMQESQHRRLWLSVGAVVLGLGVWATLF 59 M S++ L+A + +VA+L++Y AL+++ R+ V+ + R +W GA+ LG+G+W+ F Sbjct: 1 MQSSYNPWLVAMSFVVATLASYTALDLTGRIYVLASRRLRHVWRMGGALALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D T +L L +G+++ + L+ + +RL GG +G I Sbjct: 61 VAMLAFSLPIPLGYDFADTAYSLALAIGASYLALCLTTHTQLTAARLVGGGAFMGLGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 + +AA+++ P + Y+ +L + + + A +L++ R Sbjct: 121 MHYSGMAALRMSPGISYRPAWFAASLAIAIGASSAALWM----------ARALSNDDARH 170 Query: 180 VL-----AALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMAL 234 VL AAL++ + + + A AP A A + L ++ F + + Sbjct: 171 VLRKRFGAALVMAIAISGMHYVAMAAAEFAPGAICGAAAGVNAAWLATSVILFTFAILIV 230 Query: 235 ALVISGVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKT 293 L++S R L V + N +++ AT D LTGLPNRA L +RI+ A+ ARR Sbjct: 231 TLLLSRFDARTSFLVGAVSKLNGQIVRLATLDTLTGLPNRATLTERIERAIHAARRQRSL 290 Query: 294 FAVLFMDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLS 353 FA+LFMDLDGFK INDSLGH+ GD +L A AQR+ C+R D VAR+GGDEFVV+ NL+ Sbjct: 291 FAILFMDLDGFKTINDSLGHSAGDQVLAAFAQRLLICVRAGDTVARLGGDEFVVLSENLA 350 Query: 354 SPDVVEQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAK 413 S L+E +L +R+D D L+V SIGIA++P GDSVD L+K+ADAAMYEAK Sbjct: 351 SRMDAAALAEGVLERMRRDTWADSQPLQVMPSIGIALFPEDGDSVDTLLKHADAAMYEAK 410 Query: 414 QSGRNTYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLR 473 ++GR+TYRFFE M+ +A R LQ++ AL++A+ E+ F LHFQPK+ G S+ L G EAL+R Sbjct: 411 RAGRSTYRFFERRMNEAATRTLQIQNALREALAERHFTLHFQPKFDGKSETLAGAEALIR 470 Query: 474 WTHPQLGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ 533 HPQLG +AP EFIPIAERSGQI+ IG WVL+ C QI RW A G+ P+KVA+NLSP Q Sbjct: 471 LHHPQLGTLAPLEFIPIAERSGQIVQIGYWVLRETCRQIRRWIAQGLPPIKVAINLSPRQ 530 Query: 534 -MRTDLVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFG 592 ++ DLV ++++V A G+ +++MFEITET AM+D R+ ++ E QA GF+IAIDDFG Sbjct: 531 LLQADLVPTMLDIVNAEGVRCEQIMFEITETVAMQDAARTIEMLREFQASGFEIAIDDFG 590 Query: 593 TGYSSLAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETE 652 TGYSSLAYL +F +Q+KIDRFFT+ LD G AIV+AIIALAH+L+M+VVAEGVETE Sbjct: 591 TGYSSLAYLQRFRVKQLKIDRFFTNGLDAHGEEGSAIVSAIIALAHSLEMDVVAEGVETE 650 Query: 653 GQLRELQLLHCDQVQGFLLGRPAEAPSVPGLVQ 685 QL L+ + CD++QGFLLG+P A + L++ Sbjct: 651 SQLHMLKAMRCDEMQGFLLGKPLTAEAFGDLLR 683 >ref|YP_003909357.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. CCGE1003] gb|ADN60066.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. CCGE1003] Length = 692 Score = 571 bits (1472), Expect = e-160, Method: Compositional matrix adjust. Identities = 307/693 (44%), Positives = 444/693 (64%), Gaps = 18/693 (2%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERM-VMQESQHRRLWLSVGAVVLGLGVWATLF 59 M S++ L+ + VA+L++Y AL+++ R+ V+ + R++W GA LG+G+W+ F Sbjct: 1 MQSSYNPWLVVMSFFVATLASYTALDLTGRIFVLASPRLRQVWRMGGAAALGIGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D T +L L +G+++ + L+ R +RL GG +G I Sbjct: 61 VAMLAFSLPIPLGYDFADTAYSLALAIGASYLALCLTTHARLTATRLVAGGAFMGLGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 + +AA+++ P + YQ +L + + + A +L++ R Sbjct: 121 MHYSGMAALRMSPGISYQPTWFAASLAIAVAAATAALWM----------ARALSNDDARH 170 Query: 180 VL-----AALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMAL 234 VL AAL++ + + AG+ A AP A A + L ++ +++ Sbjct: 171 VLKKRFGAALVMAVAISGMHYAGMAAAEFAPGAICGAAAGVHAGWLATSVILFTLAILSV 230 Query: 235 ALVISGVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKT 293 L++S R L V + N ++L AT D LTGLPNRA L +RI+HA+ RR Sbjct: 231 TLLLSRFDARTSFLVGAVSKLNGQILQLATLDTLTGLPNRATLTERIEHAIHARRRQRSL 290 Query: 294 FAVLFMDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLS 353 FAVLFMD+DGFK INDSLGH+ GD +L A AQR+ QC+R D VAR+GGDEFVV+ L+ Sbjct: 291 FAVLFMDIDGFKTINDSLGHSAGDQVLSAFAQRLLQCVRAGDTVARLGGDEFVVLAEQLA 350 Query: 354 SPDVVEQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAK 413 S + L+E++L +R+D D L+V SIGIA++P GD+V+ L+K+ADAAMYEAK Sbjct: 351 SRNDAGALAEDVLERMRRDTWADSQPLQVMPSIGIALFPEDGDTVETLLKHADAAMYEAK 410 Query: 414 QSGRNTYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLR 473 ++GR+TYRFFE M+ +A+R LQ++ AL++A+ EQ F LHFQPK+ G S+ L G EAL+R Sbjct: 411 RAGRSTYRFFERRMNEAAVRTLQIQNALREALAEQHFTLHFQPKFHGKSESLAGAEALIR 470 Query: 474 WTHPQLGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ 533 HPQLG +AP EFIPIAERSGQI+ IG WVL+ C QI RW A G+ +KVA+NLSP Q Sbjct: 471 LHHPQLGTLAPLEFIPIAERSGQIVQIGYWVLREACRQIRRWTAQGLPAIKVAINLSPRQ 530 Query: 534 -MRTDLVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFG 592 ++ DLV ++E+V G++ +++MFEITET AM+D R+ ++ E A GF++AIDDFG Sbjct: 531 LLQADLVPTMLEIVNDEGVSCEQIMFEITETVAMQDAARTIEMLREFHASGFEVAIDDFG 590 Query: 593 TGYSSLAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETE 652 TGYSSLAYL +F +Q+KIDRFFT+ LD G AIV+AII LAH+L+M+VVAEGVETE Sbjct: 591 TGYSSLAYLQRFRVKQLKIDRFFTNGLDAHGPEGSAIVSAIIGLAHSLEMDVVAEGVETE 650 Query: 653 GQLRELQLLHCDQVQGFLLGRPAEAPSVPGLVQ 685 QL L+ + CD++QGFLLG+P A + L++ Sbjct: 651 SQLHMLKAMRCDEMQGFLLGKPLTAEAFGDLLR 683 >ref|YP_001860890.1| diguanylate cyclase/phosphodiesterase [Burkholderia phymatum STM815] gb|ACC73844.1| diguanylate cyclase/phosphodiesterase [Burkholderia phymatum STM815] Length = 689 Score = 570 bits (1468), Expect = e-160, Method: Compositional matrix adjust. Identities = 305/694 (43%), Positives = 448/694 (64%), Gaps = 18/694 (2%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERM-VMQESQHRRLWLSVGAVVLGLGVWATLF 59 M +++ L+ ++ VA+L++Y AL+++ R+ M ++ R LWL+ GA +G GVW+ F Sbjct: 1 MQSTYNLGLVVVSLAVATLASYTALDLAGRISTMASARLRHLWLAGGAAAMGTGVWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D+ +T +L + + +++ +H RL GG+ +G I Sbjct: 61 IGMLAFSLPIPLGYDLAITGCSLGIAMIVSYFALHQVARPTLPIKRLVTGGVLMGFGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 + +AAM++ P + Y+ L ++ + + + + A +L R Sbjct: 121 MHYTGMAAMRMEPGIRYRPGLFAASIAIAIAASIAALWI----------AHTLRDSNQHR 170 Query: 180 VL-----AALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMAL 234 VL AA ++GL + G+ A P + A + + L I+ F + + Sbjct: 171 VLLKRLGAACVMGLAITGMHYTGMAAADFQPGSICGAARGVNAQWLATTILLFTFAILIV 230 Query: 235 ALVISGVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKT 293 L++S R L V N++++ AT+D LT LPNR L +RI+HA+ ++ NG+ Sbjct: 231 TLILSRFDARTTFLAGSVSLLNNQIVRLATYDTLTNLPNRVTLTERIEHAIRTSKLNGRG 290 Query: 294 FAVLFMDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLS 353 FA+LFMDLDGFK INDSLGHA GD +L + + +RQC+R D VAR+GGDEFVV+ +L Sbjct: 291 FAILFMDLDGFKTINDSLGHAFGDEVLKSFSHSLRQCVRNVDTVARLGGDEFVVLAESLG 350 Query: 354 SPDVVEQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAK 413 +P ++++E +L +R+ + TL+V SIGIA+YP G SVD L+K+ADAAMYEAK Sbjct: 351 APQDAQKMAEAVLDRMRKGIETQSQTLQVMPSIGIALYPQDGHSVDELLKHADAAMYEAK 410 Query: 414 QSGRNTYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLR 473 + GR+TYRFFE M+ +AMR L+++ AL +A+ + F LHFQPK+RG S E+ G EAL+R Sbjct: 411 RGGRSTYRFFEAHMNEAAMRTLKIQSALHEALGKGYFSLHFQPKFRGDSGEVAGAEALIR 470 Query: 474 WTHPQLGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ 533 HP++G +AP +FIPIAERSGQI+ IG WV++ C QI RW+A+G+ +KVA+NLSP Q Sbjct: 471 LNHPEIGALAPMDFIPIAERSGQIVQIGYWVVRETCRQIRRWEASGLPSMKVAINLSPRQ 530 Query: 534 M-RTDLVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFG 592 M + DLVA+ +E+V A G+ ++MFEITET AM+D ++ +I E QA GF+I+IDDFG Sbjct: 531 MTQPDLVAKTLEIVHAEGVDCSQVMFEITETVAMQDAAKTTEMIREFQASGFEISIDDFG 590 Query: 593 TGYSSLAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETE 652 TGYSSLAYL +F +Q+KIDRFFT+ LD D H G AIV AIIALAH+L+M+VVAEGVET Sbjct: 591 TGYSSLAYLQRFRVKQLKIDRFFTNGLDADGHEGSAIVQAIIALAHSLEMDVVAEGVETA 650 Query: 653 GQLRELQLLHCDQVQGFLLGRPAEAPSVPGLVQA 686 QL +L+ L CD++QGFLLGRP A + L+QA Sbjct: 651 SQLDKLKDLQCDEMQGFLLGRPLTADAFSELLQA 684 >ref|YP_003607041.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. CCGE1002] gb|ADG17530.1| diguanylate cyclase/phosphodiesterase with MHYT sensor [Burkholderia sp. CCGE1002] Length = 694 Score = 566 bits (1459), Expect = e-159, Method: Compositional matrix adjust. Identities = 300/689 (43%), Positives = 444/689 (64%), Gaps = 8/689 (1%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERMVMQESQHRR-LWLSVGAVVLGLGVWATLF 59 M S++ L+A + VA+L++Y AL+++ R+ + S RR W GA+ LG+G+W+ F Sbjct: 1 MHSSYNLWLVAISFAVATLASYTALDLTGRIFLLASARRRQAWRLGGALALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D+ LT +L L +G+++ + L+ +R P+RL GG +G I Sbjct: 61 VAMLAFSLPIPLGYDLGLTAYSLALAIGASYLALFLTTQQRLTPARLLAGGAVMGIGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 + +AA+++ PA+ YQ V ++ + + + A + + +R Sbjct: 121 MHYTGMAALRMAPAIHYQPVWFAASVAIAIGASSAALWMARALSNEHER-----HIARKR 175 Query: 180 VLAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVIS 239 + AAL++G+ + + A AP A + + + L ++ L F + + L++S Sbjct: 176 LAAALVMGVAISGMHYTAMAAADFAPGAICGAASDMDAQWLATAVILLTFAVLIVTLMLS 235 Query: 240 GVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLF 298 R L V + N +++ AT D LTGLPNRA L +RI+ A+ ARR +FAVLF Sbjct: 236 RFDVRTTFLLGAVSKLNGQIVRLATLDALTGLPNRATLTERIERAISGARRQRTSFAVLF 295 Query: 299 MDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVV 358 MDLDGFK INDSLGH+ GD +L A AQR++QC+R D VAR+GGDEFVV+ +L+S D Sbjct: 296 MDLDGFKTINDSLGHSAGDAVLSAFAQRLQQCVRSSDTVARLGGDEFVVLAEHLTSGDDA 355 Query: 359 EQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRN 418 L++ +L +RQ D+ L+V SIGIA+YP GDSV+ L+++ADAAMYEAK++GR Sbjct: 356 AALADGVLERMRQGTWSDEQPLQVMPSIGIALYPRDGDSVETLLQHADAAMYEAKRAGRG 415 Query: 419 TYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQ 478 TYRFFE +M+ +A R LQ++Q L A ++F L FQPK++ L G EAL+R P+ Sbjct: 416 TYRFFERSMNEAATRTLQIQQVLHDAFANERFSLVFQPKFQRGGDALAGAEALIRLHDPE 475 Query: 479 LGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ-MRTD 537 LG + PAEFIP+AERSGQI+ IG WV++ C +I W G+ +KVA+NLSP Q ++ D Sbjct: 476 LGTLTPAEFIPVAERSGQIVQIGYWVVRETCRRIRGWIEQGLPAMKVAINLSPRQLLQPD 535 Query: 538 LVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSS 597 LV I+E+V G+A +++MFEITE+ AM+D R+ VI QA GFDI+IDDFGTGYSS Sbjct: 536 LVETILEIVRTEGVACEQIMFEITESVAMQDAARTVDVIRAFQASGFDISIDDFGTGYSS 595 Query: 598 LAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRE 657 LAYL +F +Q+KIDRFFT LD + +G AIV+AIIALAH+L+M+VVAEGVET+ QL + Sbjct: 596 LAYLQRFQVKQLKIDRFFTHGLDANGAAGSAIVSAIIALAHSLEMDVVAEGVETQSQLDK 655 Query: 658 LQLLHCDQVQGFLLGRPAEAPSVPGLVQA 686 L+ + CD++QG+LLG+P A ++++ Sbjct: 656 LRSMMCDEMQGYLLGKPVSAEDFGAMLRS 684 >ref|ZP_03265056.1| diguanylate cyclase/phosphodiesterase [Burkholderia sp. H160] gb|EEA03307.1| diguanylate cyclase/phosphodiesterase [Burkholderia sp. H160] Length = 696 Score = 565 bits (1455), Expect = e-158, Method: Compositional matrix adjust. Identities = 300/689 (43%), Positives = 447/689 (64%), Gaps = 8/689 (1%) Query: 1 MSGSFHFLLLAFAVLVASLSAYAALEVSERM-VMQESQHRRLWLSVGAVVLGLGVWATLF 59 M S++ L+A + VA+L++Y AL+++ R+ ++ ++ R W GA+ LG+G+W+ F Sbjct: 1 MHSSYNLWLVAISFAVATLASYTALDLTGRIFLLASARGRHAWRLGGALALGVGIWSMHF 60 Query: 60 LTVAALGLSMPVGFDIRLTVLALLLCLGSAFYLMHLSGLRRPHPSRLAIGGLSIGAAINA 119 + + A L +P+G+D+ LT +L L +G+++ + ++ R P RL GG+ +G I Sbjct: 61 VAMLAFSLPIPLGYDLTLTACSLALAIGASYLALCMTTRARLTPGRLLAGGVLMGIGIAG 120 Query: 120 AFHMALAAMQLLPALLYQQVLLGLALLLTELIGVFIVALFSASNGRKPKAGSLNSQQTRR 179 + +AA+++ PA+ YQ ++ + + + A + + +L +R Sbjct: 121 MHYTGMAALRMAPAIEYQPAWFVASIAIAIGASSAALWMARALSNEDERHIAL-----KR 175 Query: 180 VLAALLVGLGLVAAATAGLRALVIAPHTQSLAVASLLREHLVNGIVFLAFLAMALALVIS 239 + AAL++G+ + AG+ A AP A + L ++ L + + L++S Sbjct: 176 LAAALVMGVAISGMHYAGMAAARFAPDAICGAANDINSTWLATSVILLTLAVLTVTLMLS 235 Query: 240 GVQ-RNQVLKRIVGRTNDKLLHFATHDVLTGLPNRALLADRIQHAVEVARRNGKTFAVLF 298 R L + + N +++ AT D LTGLPNRA L +RI+ A+ VARR +FAVLF Sbjct: 236 RFDVRTTFLLGAMSKLNGQVVRLATLDALTGLPNRATLTERIERAISVARRQHSSFAVLF 295 Query: 299 MDLDGFKAINDSLGHAVGDGLLVAVAQRIRQCLRGEDMVARIGGDEFVVVVGNLSSPDVV 358 MDLDGFK INDSLGH+ GD +L A A+R+ QC+R D VAR+GGDEFVV+ +L+S + Sbjct: 296 MDLDGFKTINDSLGHSTGDAVLSAFARRLLQCVRSTDTVARLGGDEFVVLAEHLASGNDA 355 Query: 359 EQLSENILAALRQDFQIDDATLRVTSSIGIAVYPNSGDSVDALMKNADAAMYEAKQSGRN 418 +L++ +L +RQ D+ L+V SIGIA++P GD+VD L+K+ADAAMYEAK++GR Sbjct: 356 AELADGVLDRMRQGTWSDEQPLQVMPSIGIALFPRDGDTVDTLLKHADAAMYEAKRAGRG 415 Query: 419 TYRFFEPAMHASAMRHLQVRQALQQAIDEQQFRLHFQPKYRGASKELTGLEALLRWTHPQ 478 TYRFFE +M+ +AMR LQ++QAL +A+ +F L FQPK+ G LTG EAL+R P+ Sbjct: 416 TYRFFERSMNEAAMRTLQIQQALHEALLNDRFSLQFQPKFHGDGDALTGAEALIRLYDPK 475 Query: 479 LGEMAPAEFIPIAERSGQILCIGDWVLQAVCEQIARWDAAGMKPVKVALNLSPLQ-MRTD 537 +G +AP EFIP+AERSGQI+ IG WV+ C +I W G+ +KVA+NLSP Q ++ D Sbjct: 476 MGTLAPLEFIPVAERSGQIVQIGYWVVGETCRRIRGWIEQGLPAMKVAINLSPRQLLQPD 535 Query: 538 LVARIVELVGAAGIAPQRLMFEITETAAMKDVERSQRVIGELQALGFDIAIDDFGTGYSS 597 LV ++++V + G+A +++MFEITE+ AM D R+ VI QA GFDI+IDDFGTGYSS Sbjct: 536 LVETMLDIVRSEGVACEQIMFEITESVAMHDAARTVEVIRAFQASGFDISIDDFGTGYSS 595 Query: 598 LAYLAQFHCRQIKIDRFFTSRLDGDDHSGRAIVAAIIALAHALQMEVVAEGVETEGQLRE 657 LAYL +F +Q+KIDRFFTS LD +G AIV+AIIALAH+L+M+VVAEGVET+ Q + Sbjct: 596 LAYLQRFKAKQLKIDRFFTSGLDTHGAAGSAIVSAIIALAHSLEMDVVAEGVETQSQFDK 655 Query: 658 LQLLHCDQVQGFLLGRPAEAPSVPGLVQA 686 L+ + CD++QGFLLG+P A L++A Sbjct: 656 LRSMMCDEMQGFLLGKPINADDFGELLRA 684