BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0144.p (423 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISB4.1 D8ISB4_HERSS 5-aminolevulinic acid synthase protein EC=... 866 0.0 B0JFT4.1 B0JFT4_MICAN Class I/II aminotransferase 467 e-129 E0U780.1 E0U780_CYAP2 Aminotransferase class I and II 466 e-129 E3J570.1 E3J570_FRASU Aminotransferase class I and II 382 e-104 Q2JBF2.1 Q2JBF2_FRASC Aminotransferase, class I and II 379 e-103 A4Z2A0.1 A4Z2A0_BRASO 5-aminolevulinic acid synthase (ALAS) EC=2... 176 8e-42 Q6RVB3.1 Q6RVB3_RHOPA 5-aminolevulinic acid synthase 175 1e-41 Q07H78.1 Q07H78_RHOP5 5-aminolevulinate synthase EC=2.3.1.37 174 2e-41 Q2IRB4.1 Q2IRB4_RHOP2 5-aminolevulinate synthase EC=2.3.1.37 172 8e-41 E6VBS5.1 E6VBS5_RHOPX 5-aminolevulinic acid synthase EC=2.3.1.37 172 1e-40 >D8ISB4.1 D8ISB4_HERSS 5-aminolevulinic acid synthase protein EC=2.3.1.37 Length = 423 Score = 866 bits (2237), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/423 (99%), Positives = 423/423 (100%) Query: 1 MSNSSKSARWGFQRFVASSVAEGFLHEPVIMQGMSGAEVSRNGRSYVNFSGINYLGWQQD 60 MSNSSKSARWGFQRFVASSVAEGFLHEPVIMQGMSGAEVSRNGRSYVNFSGINYLGWQQD Sbjct: 1 MSNSSKSARWGFQRFVASSVAEGFLHEPVIMQGMSGAEVSRNGRSYVNFSGINYLGWQQD 60 Query: 61 ARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANIGF 120 AR+LDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANIGF Sbjct: 61 ARVLDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANIGF 120 Query: 121 INAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLTAV 180 INAMTA+FGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLTAV Sbjct: 121 INAMTAKFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLTAV 180 Query: 181 LAKLGGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPFHE 240 LAKLGGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPFHE Sbjct: 181 LAKLGGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPFHE 240 Query: 241 QFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAVFI 300 QFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAVFI Sbjct: 241 QFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAVFI 300 Query: 301 IERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALEQQ 360 IERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALEQQ Sbjct: 301 IERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALEQQ 360 Query: 361 GFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLKDLLGQGASRDAIAGAEFVGH 420 GFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLKDLLGQGASRDAIAGAEFVGH Sbjct: 361 GFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLKDLLGQGASRDAIAGAEFVGH 420 Query: 421 RRR 423 R+R Sbjct: 421 RQR 423 >B0JFT4.1 B0JFT4_MICAN Class I/II aminotransferase Length = 440 Score = 467 bits (1202), Expect = e-129, Method: Compositional matrix adjust. Identities = 212/402 (52%), Positives = 294/402 (73%), Gaps = 2/402 (0%) Query: 1 MSNSSKSARWGFQRFVASSVAEGFL--HEPVIMQGMSGAEVSRNGRSYVNFSGINYLGWQ 58 MS S ++WG ++F+ + A GFL +M GMSG+ + R+GR +N SGIN+LG Q Sbjct: 31 MSPSKNPSQWGNEKFLDDAEAAGFLLGDGIPVMDGMSGSRIKRDGREMINLSGINFLGLQ 90 Query: 59 QDARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANI 118 Q+ + ++ F ++ R+YGL+TGGSR TQG+ PHL LE ++ + K+ TL+F +G LANI Sbjct: 91 QEEQFVEIFCKNTRQYGLATGGSRLTQGVSRPHLLLEQKMNEIWQKDYTLTFGTGALANI 150 Query: 119 GFINAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLT 178 GFINAMT+ FGF + IDN+D V + DR+CHWSLW ++ K G + AFKHND + L Sbjct: 151 GFINAMTSSFGFDATVTIDNQDVVFVLDRDCHWSLWNPLANRKLGSQVFAFKHNDPSSLE 210 Query: 179 AVLAKLGGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPF 238 VL K+ + IVVFE++YSSDGSVAP+GE++++C+R+ ALSY+DDANGFM+YG+P RPF Sbjct: 211 QVLKKIKSSRVIVVFETVYSSDGSVAPVGELIEICERYGALSYVDDANGFMIYGTPNRPF 270 Query: 239 HEQFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAV 298 +++++ +RRA FIMVS SK+VG+EGGAISG EF+ +FE+LSGTS+FTA +QPPTA + Sbjct: 271 YQEYKALRRATFIMVSFSKAVGIEGGAISGPKEFVKSFEILSGTSLFTATMQPPTAATNL 330 Query: 299 FIIERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALE 358 II+ L NP IM+DYL R R L G LND SYITS++IG+D+ AEQVR+ L Sbjct: 331 EIIQHLEKNPKIMDDYLKRCLQLRETLINLGFHLNDVPSYITSIIIGQDEVAEQVRRDLL 390 Query: 359 QQGFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLK 400 G+C+PIFRYPAV+ +AL+RL+++ HT+ I+ FV +LK Sbjct: 391 DMGYCIPIFRYPAVERGKALIRLMINNKHTDEDINLFVEALK 432 >E0U780.1 E0U780_CYAP2 Aminotransferase class I and II Length = 424 Score = 466 bits (1200), Expect = e-129, Method: Compositional matrix adjust. Identities = 216/398 (54%), Positives = 288/398 (72%), Gaps = 1/398 (0%) Query: 6 KSARWGFQRFVASSVAEGFLHEPV-IMQGMSGAEVSRNGRSYVNFSGINYLGWQQDARIL 64 K + W F+ S + G+L + + IM GMSG+ + RNGR +N +GIN LG Q++ + Sbjct: 21 KYSNWPNSAFLESCQSAGYLLDQINIMDGMSGSRIERNGRQLINLAGINILGLQENPEFI 80 Query: 65 DAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANIGFINAM 124 + F + R+YGL+TGGSR TQG+C PH LE ++ + GK TL+F +G LANIGFINAM Sbjct: 81 EIFCDKTRQYGLATGGSRLTQGVCVPHWLLEQKMNEIWGKNYTLTFGTGALANIGFINAM 140 Query: 125 TARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLTAVLAKL 184 TA + IDNRDAV + DR+CHWSLW S LK+GE L +FKHND DL VL K+ Sbjct: 141 TAALPVDGQIKIDNRDAVFVLDRDCHWSLWNPTSKLKYGEQLFSFKHNDPDDLEKVLKKI 200 Query: 185 GGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPFHEQFRH 244 K +VVFE++YSSDGSVAPIG++LDVC+++ ALSY+DDANGFM+YG RPF+E++ Sbjct: 201 NSPKVVVVFETVYSSDGSVAPIGQLLDVCEKYGALSYVDDANGFMIYGERNRPFYEEYLA 260 Query: 245 MRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAVFIIERL 304 + RA FIMVS SK++G+EGGAISG AEF+ FE LSGT++FTA +QPPTA + II L Sbjct: 261 LSRATFIMVSFSKAIGIEGGAISGPAEFVATFEFLSGTALFTATMQPPTAATNLEIINYL 320 Query: 305 RANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALEQQGFCV 364 +A+P IM++YL R + FR L SG LN+T SYI SV +G+D+ AEQVR+ L + G+C+ Sbjct: 321 QAHPEIMDNYLLRCSQFRQILLDSGFCLNNTPSYINSVYVGKDEVAEQVRRELLELGYCI 380 Query: 365 PIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLKDL 402 PIFRYPAVK NQA++RL+L+ HTE I++F+ LK + Sbjct: 381 PIFRYPAVKRNQAVIRLMLNNQHTESDIEKFIQDLKKV 418 >E3J570.1 E3J570_FRASU Aminotransferase class I and II Length = 411 Score = 382 bits (981), Expect = e-104, Method: Compositional matrix adjust. Identities = 183/394 (46%), Positives = 257/394 (65%) Query: 9 RWGFQRFVASSVAEGFLHEPVIMQGMSGAEVSRNGRSYVNFSGINYLGWQQDARILDAFV 68 RWGF ++ ++ G P + ++ A +S +GR +NF+GI LGWQ D + F Sbjct: 12 RWGFSAWLDATRRSGDFVMPPELDDVNDAVISVDGRKMINFAGIGILGWQHDPEVRRVFA 71 Query: 69 ESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANIGFINAMTARF 128 E+A YGL GGSR QG+ PHL LE +++ + GKE+ L+FA+G+LAN+GF+NAM+A F Sbjct: 72 ETAATYGLVVGGSRLVQGVSRPHLELERLVAEISGKEKALTFATGLLANVGFVNAMSAAF 131 Query: 129 GFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLTAVLAKLGGRK 188 F R +DN DAVL+ DR HWS+WK + G +L AF+HND L +L +L GR Sbjct: 132 SFDDRVGVDNADAVLVLDRRSHWSVWKGTEGFERGRNLFAFRHNDPAHLRELLEQLRGRP 191 Query: 189 AIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPFHEQFRHMRRA 248 IV FE++YS+DGS+APIG ILD+C F A+S+ DDANGFMVYG+ F ++ +RR Sbjct: 192 VIVGFETVYSADGSIAPIGAILDLCDEFGAVSFADDANGFMVYGNGGHRFAAEYEALRRV 251 Query: 249 DFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAVFIIERLRANP 308 F+MVS K VGL GGA++G A+ IDAF LSGTS+FT IQPPTA V ++ R+R +P Sbjct: 252 TFLMVSFGKGVGLSGGALAGPADAIDAFHYLSGTSMFTTNIQPPTAGAIVHVLRRMRQDP 311 Query: 309 WIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALEQQGFCVPIFR 368 +ME YLDR R +L G +N T +Y+TS+ IG D +VRQ +G+ VP+F Sbjct: 312 SVMERYLDRVDGLRARLLEIGCAINPTPTYVTSIAIGSRDVGLRVRQEFLDRGYLVPMFG 371 Query: 369 YPAVKPNQALMRLILHRLHTEPQIDRFVASLKDL 402 YPAVK + A++RL+++ + ++ FV +L +L Sbjct: 372 YPAVKKDAAVIRLLMNDRIADKDLNGFVDTLAEL 405 >Q2JBF2.1 Q2JBF2_FRASC Aminotransferase, class I and II Length = 410 Score = 379 bits (973), Expect = e-103, Method: Compositional matrix adjust. Identities = 185/402 (46%), Positives = 269/402 (66%), Gaps = 1/402 (0%) Query: 1 MSNSSKSARWGFQRFVASSVAEGFLHEPVIMQGMSGAEVSRNGRSYVNFSGINYLGWQQD 60 +S ARWGF +V S+ G L + + A +S NGR VNF+GI LGWQ D Sbjct: 4 LSAEPALARWGFSEWVESARRSGELIATPELDDRNDAVISINGRKVVNFAGIGILGWQHD 63 Query: 61 ARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHGKERTLSFASGMLANIGF 120 + + FVE+A YGL GGSR QG+ PHL LE +++ + G+++ L++A+G+LAN+GF Sbjct: 64 PDVRNVFVETAMNYGLVVGGSRVVQGVARPHLELEALVAEITGRQKALTYATGLLANVGF 123 Query: 121 INAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFGESLLAFKHNDVTDLTAV 180 ++AM+ARF F+ + +DN D V + DR+ HWS+WKA KFG +L+ F+HND+ DL V Sbjct: 124 VHAMSARFSFNDQPGVDNADTVFVLDRDSHWSMWKAVERFKFGRNLINFRHNDIADLRQV 183 Query: 181 LAKLGGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYIDDANGFMVYGSPQRPFHE 240 L L GR+ +V F ++YS DGS+AP+GEILD+C F A+S++DDANGFMVYG+ F Sbjct: 184 LENLRGRRVVVGFLTVYS-DGSMAPVGEILDLCDEFGAVSFVDDANGFMVYGNGGHRFAA 242 Query: 241 QFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGTSIFTAAIQPPTADLAVFI 300 ++ +RRA F+MVS KS+GL GGA++G A+ +DAF LSGTS+FT IQPPTA V + Sbjct: 243 EYEELRRATFLMVSFGKSIGLGGGALAGPADALDAFRFLSGTSVFTTNIQPPTAGAIVHV 302 Query: 301 IERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSVMIGRDDKAEQVRQALEQQ 360 + R+R +P +ME YLDR R +L G +N T +Y+TS+ +G + A +VRQ + Sbjct: 303 LRRMRQDPSVMERYLDRVDRLRERLLGIGCTINATPTYVTSISVGSNHTAVRVRQDFLDR 362 Query: 361 GFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLKDL 402 G+ VP+F YPAV NQ ++RL+++ ++ +D F+ +L +L Sbjct: 363 GYLVPMFGYPAVNKNQTVIRLMVNNRLSDEHLDGFLDTLAEL 404 >A4Z2A0.1 A4Z2A0_BRASO 5-aminolevulinic acid synthase (ALAS) EC=2.3.1.37 Length = 409 Score = 176 bits (445), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 113/363 (31%), Positives = 180/363 (49%), Gaps = 15/363 (4%) Query: 40 SRNG-RSYVNFSGINYLGWQQDARILDAFVESARRYGLSTGGSRATQGICEPHLRLENML 98 S NG R+ V + +YLG Q +++ A VE+A R G GG+R G P ++LE L Sbjct: 40 SPNGPRNVVIWCSNDYLGMGQHPKVVGAMVETATRVGTGAGGTRNIAGTHHPLVQLEAEL 99 Query: 99 STLHGKERTLSFASGMLANIGFINAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAAS 158 + LHGKE L F SG ++N I + D +++ D H S+ + Sbjct: 100 ADLHGKEAALLFTSGYVSNQTGIATLAKLI----------PDCLILSDALNHNSMIEGVR 149 Query: 159 HLKFGESLLAFKHNDVTDLTAVLAKLG-GRKAIVVFESLYSSDGSVAPIGEILDVCQRFD 217 + G ++HND+ L +L G R ++ ESLYS DG VAP+ I D+ +R++ Sbjct: 150 --QSGCERQIWRHNDLAHLEQLLIAAGPSRPKLIACESLYSMDGDVAPLAAICDLAERYN 207 Query: 218 ALSYIDDANGFMVYGSPQRPFHEQFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFE 277 A++Y+D+ + +YG+ E+ M R D + +L+K+ G GG I+ E IDA Sbjct: 208 AMTYVDEVHAVGMYGARGGGIAERDGVMHRIDILEGTLAKAFGCLGGYIAAKGEIIDAVR 267 Query: 278 VLSGTSIFTAAIQPPTADLAVFIIERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTAS 337 + IFT A+ PP A I+ L+++ W E + DR+A + L A+GL + D + Sbjct: 268 SYAPGFIFTTALPPPICSAATAAIKHLKSSSWERERHQDRAARVKAILNAAGLPVMDNDT 327 Query: 338 YITSVMIGRDDKAEQVRQ-ALEQQGFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFV 396 +I + +G +K +Q LE+ G + YP V +R+ H + IDR Sbjct: 328 HIVPLFVGDPEKCKQASDLLLEEHGIYIQPINYPTVAKGTERLRITPSPYHDDGLIDRLA 387 Query: 397 ASL 399 +L Sbjct: 388 EAL 390 >Q6RVB3.1 Q6RVB3_RHOPA 5-aminolevulinic acid synthase Length = 409 Score = 175 bits (444), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 114/364 (31%), Positives = 183/364 (50%), Gaps = 20/364 (5%) Query: 44 RSYVNFSGINYLGWQQDARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHG 103 R V + +YLG Q +++ A VE+A R G GG+R G P + LE L+ LHG Sbjct: 45 RDVVIWCSNDYLGMGQHPKVVGAMVETATRLGTGAGGTRNIAGTHHPLVMLERELADLHG 104 Query: 104 KERTLSFASGMLANIGFINAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFG 163 KE L F SG ++N + G S+ + + + +++ D H S+ + + G Sbjct: 105 KEAALLFTSGYVSN---------QTGISTLAKLIP-NCLILSDALNHNSMIEGIR--QSG 152 Query: 164 ESLLAFKHNDVTDLTAVL-AKLGGRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYI 222 + ++HND L +L A GR ++ FESLYS DG VAP+ +I D+ +++ A++Y Sbjct: 153 CERIVWRHNDTAHLEELLRAVEPGRPVLIAFESLYSMDGDVAPMAKICDLAEKYGAMTYC 212 Query: 223 DDANGFMVYGSPQRPFHEQFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGT 282 D+ + +YG+ E+ M R D I +L+K+ G GG ISG + IDA + Sbjct: 213 DEVHAVGMYGARGAGVAERDGVMHRIDIIEATLAKAFGCLGGYISGKKDVIDAVRSYAPG 272 Query: 283 SIFTAAIQPPTADLAVFIIERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSV 342 IFT A+ PP A I L+ + W E + DR+A + L +GL + T ++I V Sbjct: 273 FIFTTALPPPICAAATAAIRHLKTSTWERERHQDRAARLKAVLNTAGLPVMPTDTHIVPV 332 Query: 343 MIGRDDKAEQVRQA----LEQQGFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVAS 398 +G AE+ ++A LE+ G + YP V + +R+ H + +DR + Sbjct: 333 FVG---DAERCKKASDLLLEKHGIYIQPINYPTVAKGKERLRITPSPYHDDDLMDRLAEA 389 Query: 399 LKDL 402 L D+ Sbjct: 390 LVDV 393 >Q07H78.1 Q07H78_RHOP5 5-aminolevulinate synthase EC=2.3.1.37 Length = 409 Score = 174 bits (442), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 112/364 (30%), Positives = 181/364 (49%), Gaps = 20/364 (5%) Query: 44 RSYVNFSGINYLGWQQDARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHG 103 R V + +YLG Q +++ A VE+A R G GG+R G P + LE ++ LHG Sbjct: 45 RDVVIWCSNDYLGMGQHPKVVGAMVETATRIGTGAGGTRNIAGTHHPLVTLEREIADLHG 104 Query: 104 KERTLSFASGMLANIGFINAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFG 163 KE L F SG ++N + G S+ + + + +++ D H S+ + Sbjct: 105 KEAALLFTSGYVSN---------QTGISTLAKLIP-NCLILSDALNHNSMIEGIRQSSC- 153 Query: 164 ESLLAFKHNDVTDLTAVLAKLG-GRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYI 222 + ++HND L +L + GR ++ FESLYS DG VAP+ +I D+ +++ A++Y Sbjct: 154 -ERIVWRHNDTAHLEELLKAVAPGRPVLIAFESLYSMDGDVAPMAKICDLAEKYGAMTYC 212 Query: 223 DDANGFMVYGSPQRPFHEQFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGT 282 D+ + +YG+ E+ M R D + +L+K+ G GG I+G E IDA + Sbjct: 213 DEVHAVGMYGAHGAGIAERDNVMHRIDILEATLAKAFGCLGGYIAGKKEVIDAVRSYAPG 272 Query: 283 SIFTAAIQPPTADLAVFIIERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSV 342 IFT A+ PP A I L+ + W E + DR+A + L +GL + T ++I V Sbjct: 273 FIFTTALPPPICAAATAAIRHLKTSTWERERHQDRAARVKSVLNTAGLPVMPTDTHIVPV 332 Query: 343 MIGRDDKAEQVRQA----LEQQGFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVAS 398 +G AE+ ++A LE+ G + YP V +R+ HT+ ID A+ Sbjct: 333 FVG---DAERCKKASDLLLEKHGIYIQPINYPTVPKGAERLRVTPSPYHTDELIDTLAAA 389 Query: 399 LKDL 402 L D+ Sbjct: 390 LVDV 393 >Q2IRB4.1 Q2IRB4_RHOP2 5-aminolevulinate synthase EC=2.3.1.37 Length = 409 Score = 172 bits (436), Expect = 8e-41, Method: Compositional matrix adjust. Identities = 111/364 (30%), Positives = 178/364 (48%), Gaps = 14/364 (3%) Query: 44 RSYVNFSGINYLGWQQDARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHG 103 R V + +YLG Q +++ A VE+ R G GG+R G P ++LE ++ LHG Sbjct: 45 RDVVIWCSNDYLGMGQHPKVIGAMVETTTRIGTGAGGTRNIAGTHHPLVQLEREIADLHG 104 Query: 104 KERTLSFASGMLANIGFINAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFG 163 KE L F SG ++N + G S+ + + +++ D H S+ + + G Sbjct: 105 KEAALLFTSGYVSN---------QTGLSTLGKLIP-NCLILSDALNHNSMIEGIR--QSG 152 Query: 164 ESLLAFKHNDVTDLTAVLAKLG-GRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYI 222 + ++HND L +L G R ++ FESLYS DG AP+ +I D+ +++DA++Y Sbjct: 153 CERVVWRHNDTAHLEELLIAAGPDRPKLIAFESLYSMDGDTAPLAKICDLAEKYDAMTYC 212 Query: 223 DDANGFMVYGSPQRPFHEQFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGT 282 D+ + +YG E+ M R D I +L+K+ G GG I+G A+ IDA + Sbjct: 213 DEVHAVGMYGPRGAGVAERDGVMARIDIIEATLAKAFGCLGGYIAGKADVIDAVRSYAPG 272 Query: 283 SIFTAAIQPPTADLAVFIIERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSV 342 IFT A+ PP A I L+A+ W E + DR+A + L +G+ + T ++I V Sbjct: 273 FIFTTALPPPICAAATAAIRHLKASTWERERHQDRAARVKAVLNNAGIPVMPTDTHIVPV 332 Query: 343 MIGRDDKAEQVRQ-ALEQQGFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASLKD 401 +G +K + LEQ G + YP V +R+ H + ID +L Sbjct: 333 FVGDAEKCKMASDLLLEQHGIYIQPINYPTVARGLERLRITPSPYHDDKLIDALAEALVQ 392 Query: 402 LLGQ 405 + GQ Sbjct: 393 VWGQ 396 >E6VBS5.1 E6VBS5_RHOPX 5-aminolevulinic acid synthase EC=2.3.1.37 Length = 409 Score = 172 bits (435), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 109/358 (30%), Positives = 179/358 (50%), Gaps = 14/358 (3%) Query: 44 RSYVNFSGINYLGWQQDARILDAFVESARRYGLSTGGSRATQGICEPHLRLENMLSTLHG 103 R V + +YLG Q +++ A VE+A R G GG+R G P ++LE +++LHG Sbjct: 45 RDVVIWCSNDYLGMGQHPKVVGAMVETATRIGTGAGGTRNIAGTHHPLVQLEQEIASLHG 104 Query: 104 KERTLSFASGMLANIGFINAMTARFGFSSRSAIDNRDAVLIFDRECHWSLWKAASHLKFG 163 KE L F SG ++N + G S+ + + +++ D H S+ + + G Sbjct: 105 KEAALLFTSGYVSN---------QTGLSTLGKL-IPNCLILSDALNHNSMIEGIR--QSG 152 Query: 164 ESLLAFKHNDVTDLTAVLAKLG-GRKAIVVFESLYSSDGSVAPIGEILDVCQRFDALSYI 222 + ++HND L +L G R ++ FESLYS DG AP+ +I D+ ++++A++Y Sbjct: 153 CERVVWRHNDTAHLEELLIAAGPDRPKLIAFESLYSMDGDTAPLAKICDLAEKYNAMTYC 212 Query: 223 DDANGFMVYGSPQRPFHEQFRHMRRADFIMVSLSKSVGLEGGAISGSAEFIDAFEVLSGT 282 D+ + +YG+ E+ M R D I +L+K+ G GG I+G E IDA + Sbjct: 213 DEVHAVGMYGAHGAGVAERDGVMARIDIIEATLAKAFGCLGGYITGKTEVIDAVRSYAPG 272 Query: 283 SIFTAAIQPPTADLAVFIIERLRANPWIMEDYLDRSAMFRLKLQASGLRLNDTASYITSV 342 IFT A+ PP A I+ LRA+ W E + DR+A + L +G+ + T ++I V Sbjct: 273 FIFTTALPPPICAAATAAIKHLRASTWERERHQDRAARVKAVLNNAGIPVMPTDTHIVPV 332 Query: 343 MIGRDDKAEQVRQ-ALEQQGFCVPIFRYPAVKPNQALMRLILHRLHTEPQIDRFVASL 399 +G +K ++ L+Q G + YP V +R+ H + ID +L Sbjct: 333 FVGDAEKCKKASDLLLDQHGIYIQPINYPTVARGLERLRITPSPYHDDKLIDALAEAL 390