BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0051.p (548 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRP5.1 D8IRP5_HERSS Permease of the major facilitator superfam... 1052 0.0 B2SXM1.1 B2SXM1_BURPP Drug resistance transporter, EmrB/QacA sub... 770 0.0 E8YMG5.1 E8YMG5_9BURK Major facilitator superfamily MFS_1 765 0.0 E1T722.1 E1T722_BURSG Major facilitator superfamily MFS_1 753 0.0 D5WBD4.1 D5WBD4_BURSC Major facilitator superfamily MFS_1 753 0.0 D5NMN7.1 D5NMN7_9BURK Drug resistance transporter, EmrB/QacA sub... 751 0.0 Q145Q2.1 Q145Q2_BURXL Major facilitator superfamily (MFS) multid... 751 0.0 B5WUX9.1 B5WUX9_9BURK Major facilitator superfamily MFS_1 749 0.0 A2W7G3.1 A2W7G3_9BURK Major facilitator superfamily (MFS_1) tran... 745 0.0 B1FWS5.1 B1FWS5_9BURK Drug resistance transporter, EmrB/QacA sub... 743 0.0 >D8IRP5.1 D8IRP5_HERSS Permease of the major facilitator superfamily protein Length = 532 Score = 1052 bits (2720), Expect = 0.0, Method: Compositional matrix adjust. Identities = 531/532 (99%), Positives = 531/532 (99%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MALHTDSAHSSGQVLPFRES LATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW Sbjct: 1 MALHTDSAHSSGQVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG Sbjct: 61 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY Sbjct: 121 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS Sbjct: 181 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP Sbjct: 241 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI Sbjct: 301 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML Sbjct: 361 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS Sbjct: 421 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVMSE 548 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVMSE Sbjct: 481 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVMSE 532 >B2SXM1.1 B2SXM1_BURPP Drug resistance transporter, EmrB/QacA subfamily Length = 531 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/530 (70%), Positives = 445/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LGI FV MLVALDQT+VGTALPTIVAELKGFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSVITVPIFGRLGDY+GRKPFVIASI+VF AS LCGMAN+MLFLVLARGLQG Sbjct: 61 VATSYLLTSVITVPIFGRLGDYYGRKPFVIASIVVFTAASVLCGMANNMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGA+LI+++LGSLQL VELLPK GVT Sbjct: 181 VNLPVGLLSLFFVWRFLPHLRHVEHEGKMRLDWPGAVLIAVALGSLQLFVELLPKHGVTL 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 G + LL +SVA+ YALW+WE+R ILP +M R+R+LA+LF L+VL GF+MFS+L YAP Sbjct: 241 GAIALLVLSVASAYALWQWEKRCPTAILPVDMFRNRSLAALFTLAVLGGFSMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAGL+ITPLV IT+ SI NGRI++R+ NPNLM+ +GF L+A +CLG+ Sbjct: 301 LLFQGGFGMSPKEAGLVITPLVVFITIGSIANGRIVSRVRNPNLMLYIGFTLLALACLGV 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R + L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGM+ Sbjct: 361 VVATRAMPQWLLMSFMIVGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLVS MY +GV AL+ DHA+QWL D DP++L+N D Q+ LL QL AGH+G+ Sbjct: 421 GTALTGTLVSHMYASGVRSALDNDHASQWLADLGDPQILINRDAQATLLGQLTHAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE AREALV AIH+G+A+A + A V +W RRVPPI+ +K+EPV+ Sbjct: 481 MLLETAREALVSAIHLGLAMAAIIAAVSVWQSRRVPPIKL--QRKLEPVI 528 >E8YMG5.1 E8YMG5_9BURK Major facilitator superfamily MFS_1 Length = 531 Score = 765 bits (1975), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/530 (69%), Positives = 442/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LGI FV MLVALDQT+VGTALPTIVAELKGFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSVITVPIFGRLGDY+GRKPFVIASI+VF GAS LCG+AN+MLFLVLARGLQG Sbjct: 61 VATSYLLTSVITVPIFGRLGDYYGRKPFVIASIVVFTGASVLCGVANNMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGA LI+++LGSLQL VELLPK G+T Sbjct: 181 VNLPVGILSLFFVWRFLPHLRHVEHKGKMRLDWPGAALIAVALGSLQLFVELLPKHGLTL 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 G LL +SVA+ YALW+WE+R ILP +M R+++LA+LF L+VL GF MFS+L YAP Sbjct: 241 GACALLVLSVASAYALWQWEKRCPTAILPVDMFRNQSLAALFTLAVLGGFTMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAG++ITPLV IT+ SI NGR+++R+ NPNLM+ +GFAL+A SCLG+ Sbjct: 301 LLFQGGFGMSPKEAGVVITPLVVFITIGSIANGRVVSRVRNPNLMLYVGFALVALSCLGV 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGM+ Sbjct: 361 VVATRSMPHWLLMSFMVLGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLVS MY +GV LE DHA+QW D DP++L+NH+ Q+ LL QL QAGH+G+ Sbjct: 421 GTALTGTLVSHMYASGVRSTLESDHASQWFGDLGDPQILINHEAQASLLGQLAQAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE ARE LV AIH G+A+A + A+V +W RRVPPI+ +K+EPV+ Sbjct: 481 MLLETARETLVAAIHFGLAMAAIVAVVSVWQSRRVPPIKL--QRKLEPVI 528 >E1T722.1 E1T722_BURSG Major facilitator superfamily MFS_1 Length = 531 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/530 (68%), Positives = 440/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES L+ LGI FV MLVALDQT+VGTALPTIVAELKGFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLSMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSVITVPIFGRLGDY+GRKPFVIASI+VF GAS LCG+A++MLFLVLARGLQG Sbjct: 61 VATSYLLTSVITVPIFGRLGDYYGRKPFVIASIVVFTGASVLCGVADNMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGA LI+++LGSLQL VELLPK G++ Sbjct: 181 VNLPVGMLSLFFVWRFLPHLRHVEHEGKMRLDWPGAALIAVALGSLQLFVELLPKHGLSW 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 G LL +SVA+ YALW+WE+R ILP +M R+R+LA+LF L+VL GF MFS+L YAP Sbjct: 241 GACALLVLSVASAYALWQWEKRCPTAILPVDMFRNRSLAALFTLAVLGGFTMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAG++ITPLV IT+ SI NGR+++R+ NPNLM+ +GF L+A +C+G Sbjct: 301 LLFQGGFGMSPKEAGVVITPLVVFITIGSIANGRVVSRVRNPNLMLYVGFTLLALACVGA 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGM+ Sbjct: 361 VIATRSMPHWLLMSFMVLGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLVS MY +GV ALE D A+QW D SDP++L+NH+ Q+ LL QL AGH+G+ Sbjct: 421 GTALTGTLVSHMYASGVRSALERDRASQWFGDLSDPQILINHEAQASLLGQLAHAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE ARE LV AIH G+A+A + A+V +W RRVPPI+ +K+EPV+ Sbjct: 481 MLLETARETLVAAIHFGLAMAAIIAVVSVWQSRRVPPIKL--QRKLEPVI 528 >D5WBD4.1 D5WBD4_BURSC Major facilitator superfamily MFS_1 Length = 531 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/530 (68%), Positives = 441/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LGI FV MLVALDQT+VGTALPTIV+EL+GFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVSELRGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLL+SVITVPIFGRLGDY+GRKPFVIASI+VF GAS LCG AN MLFLVLARGLQG Sbjct: 61 VATSYLLSSVITVPIFGRLGDYYGRKPFVIASIVVFTGASVLCGAANDMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGALLI+++LGSLQL VELLPK G+T Sbjct: 181 VNLPVGLLSLFFVWRFLPHLRHVEHEGKMRLDWPGALLIAIALGSLQLFVELLPKHGITL 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 + LL +SVA+ ALW WE+R ILP +M +R+LA+LF L+VL GF MFS+L YAP Sbjct: 241 SVFALLGLSVASAIALWNWEKRCPTAILPVDMFHNRSLAALFTLAVLGGFTMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAGL+ITPLV IT+ SI NGR+++RI NPNLM+ +GFA++A SCLGI Sbjct: 301 LLFQGGFGMSPKEAGLVITPLVVFITIGSIANGRVVSRIKNPNLMLYIGFAMLALSCLGI 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R + L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGM+ Sbjct: 361 VVATRSMQQWVLMSFMVVGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLV+ MY +GV +ALEG A+ W D DP++L+N D Q+ L+ QL AGH+G+ Sbjct: 421 GTALTGTLVTHMYKSGVRRALEGAGASHWFGDLGDPQILINRDAQTTLVDQLTHAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE+ARE+LVGAIH+G+A+A + A+V +W RRVPP++ +K+EPV+ Sbjct: 481 MLLESARESLVGAIHLGLAMAALIAVVSVWQSRRVPPVKL--QRKLEPVI 528 >D5NMN7.1 D5NMN7_9BURK Drug resistance transporter, EmrB/QacA subfamily Length = 531 Score = 751 bits (1940), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/530 (70%), Positives = 443/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LGI FV MLVALDQT+VGTALPTIVAELKGFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSVITVPIFGRLGDY+GRKPFVIASIIVF GAS LCG AN+MLFLVLARGLQG Sbjct: 61 VATSYLLTSVITVPIFGRLGDYYGRKPFVIASIIVFTGASVLCGAANNMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGA+LI+++LGSLQL VELLPK GVT Sbjct: 181 VNLPVGLLSLFFVWRFLPHLRHVEHEGKMRLDWPGAVLIAVALGSLQLFVELLPKHGVTL 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 + LLA+S A+ YALW+WE+R ILP +M R+R+LA+LF L+VL GF MFS+L YAP Sbjct: 241 SVAALLALSAASAYALWQWEKRCPTAILPVDMFRNRSLAALFTLAVLGGFTMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAGL+ITPLV IT+ SI NGRI++R+ NPNLM+ +GF L+A +CLG+ Sbjct: 301 LLFQGGFGMSPKEAGLVITPLVVFITIGSIANGRIVSRVRNPNLMLYVGFTLLALACLGV 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R + L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGML Sbjct: 361 VVATRAMPQWLLMSFMVVGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGML 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLVS MY +GV ALE DHA+ W D DP++L+N D Q+ LL QL AGH+G+ Sbjct: 421 GTALTGTLVSHMYASGVRSALENDHASHWFADLGDPQILINRDAQTTLLGQLAHAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE+AREALV AIH+G+A+A + A+V +W RRVPPI+ +K+EPV+ Sbjct: 481 MLLESAREALVSAIHLGLAMAAIIAVVSVWQSRRVPPIKL--QRKLEPVI 528 >Q145Q2.1 Q145Q2_BURXL Major facilitator superfamily (MFS) multidrug efflux pump, EmrB/QacA subfamily Length = 531 Score = 751 bits (1940), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/530 (70%), Positives = 443/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LGI FV MLVALDQT+VGTALPTIVAELKGFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSVITVPIFGRLGDY+GRKPFVIASI+VF GAS LCG AN+MLFLVLARGLQG Sbjct: 61 VATSYLLTSVITVPIFGRLGDYYGRKPFVIASIVVFTGASVLCGAANNMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVVMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGA+LI+++LGSLQL VELLPK GVT Sbjct: 181 VNLPVGLLSLFFVWRFLPHLRHVEHEGKMRLDWPGAVLIAVALGSLQLFVELLPKHGVTL 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 + LLA+S A+ YALW+WE+R ILP +M R+R+LA+LF L+VL GF MFS+L YAP Sbjct: 241 SVAALLALSAASAYALWQWEKRCPTAILPVDMFRNRSLAALFTLAVLGGFTMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAGL+ITPLV IT+ SI NGRI++R+ NPNLM+ +GF L+A +CLG+ Sbjct: 301 LLFQGGFGMSPKEAGLVITPLVVFITIGSIANGRIVSRVRNPNLMLYVGFTLLALACLGV 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R + L+A M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGML Sbjct: 361 VVATRAMPQWLLMAFMVVGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGML 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLVS MY +GV ALE DHA+ W D DP++L+N D Q+ LL QL AGH+G+ Sbjct: 421 GTALTGTLVSHMYASGVRSALENDHASHWFADLGDPQILINRDAQTTLLGQLAHAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE+AREALV AIH+G+A+A + A+V +W RRVPPI+ +K+EPV+ Sbjct: 481 MLLESAREALVSAIHLGLAMAAIIAVVSVWQSRRVPPIKL--QRKLEPVI 528 >B5WUX9.1 B5WUX9_9BURK Major facilitator superfamily MFS_1 Length = 531 Score = 749 bits (1933), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/530 (68%), Positives = 442/530 (83%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LG+ FV MLVALDQT+VGTALPTIV+EL+GFELYAW Sbjct: 1 MAVHTTAHHSSGQVLPFRESLLAMLGVSFVAMLVALDQTVVGTALPTIVSELRGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLL+SVITVPIFGRLGDY+GRKPFVIASI+VF GAS LCG ANSMLFLVLARGLQG Sbjct: 61 VATSYLLSSVITVPIFGRLGDYYGRKPFVIASIVVFTGASVLCGAANSMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA A+GPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAIGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWR++PH+RH++H GKMRLDWPGALLI+++LGSLQL VELLPK G+T Sbjct: 181 VNLPVGLLSLFFVWRYLPHLRHVEHTGKMRLDWPGALLIAIALGSLQLFVELLPKHGITP 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 L LL +SVA+ +LWKWE+R ILP +M R+R+L +LF L+VL GF+MFS+L YAP Sbjct: 241 SALALLGLSVASAISLWKWEKRCPTAILPVDMFRNRSLTALFTLAVLGGFSMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAG++ITPLV IT+ SI NGRI++R+ NPNLM+ +GFA++A SCLGI Sbjct: 301 LLFQGGFGMSPKEAGIVITPLVVFITIGSITNGRIVSRVKNPNLMLYIGFAMVALSCLGI 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R + L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGM+ Sbjct: 361 VVATRSMQQWVLMSFMIVGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLV+ +Y +GV ALEG A+ W D DP++L+N D Q+ L+ QL AGH+G+ Sbjct: 421 GTALTGTLVTHLYKSGVRNALEGAGASHWFPDLGDPQILINRDAQTTLVDQLTHAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE+AREALVGAIH+GIA+A A+V +W RRVPPI+ +KVEPV+ Sbjct: 481 MLLESAREALVGAIHLGIAMAAAIAVVSVWQTRRVPPIKL--RRKVEPVV 528 >A2W7G3.1 A2W7G3_9BURK Major facilitator superfamily (MFS_1) transporter Length = 531 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/528 (68%), Positives = 441/528 (83%), Gaps = 2/528 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA +GI FV MLVALDQT+VGTALPTIVAEL+GF+LYAW Sbjct: 1 MAVHTAAPHSSGQVLPFRESLLAMIGISFVTMLVALDQTVVGTALPTIVAELRGFDLYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLL+SVITVPIFGRLGDY+GRKPFVI SI+VF GAS LCGMAN ML+LVLARGLQG Sbjct: 61 VATSYLLSSVITVPIFGRLGDYYGRKPFVIVSIVVFTGASVLCGMANDMLYLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA A+GPSLGG LTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAIGPSLGGVLTQSFGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWR++PH+R ++H GKMRLDWPGALLI+LSLG+LQL VE LPK G+ S Sbjct: 181 VNLPVGLLSLFFVWRYLPHLRQVEHGGKMRLDWPGALLIALSLGALQLFVEWLPKYGIAS 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 +LL V+VAA LW+WE+R AQPILPF+M +RAL++LF+L++LAGFAMFS+L YAP Sbjct: 241 WASLLLVVAVAAGVGLWQWEKRCAQPILPFDMFGNRALSTLFVLAILAGFAMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SPREAGL+ITPLV IT+ SI+NGR+ITRI NPN M+++GF L A +C GI Sbjct: 301 LLFQGGFGMSPREAGLVITPLVVFITIGSIMNGRVITRIRNPNAMLHVGFVLFAIACAGI 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ T L+A+M+AGG GLG VLPNLTVFAQQ A REHLGIATALLQSLRM+GGM+ Sbjct: 361 VVSTHATPIWMLMALMVAGGIGLGFVLPNLTVFAQQTAGREHLGIATALLQSLRMVGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTLV+QMY +GV AL +HAAQW +DP++L++ Q L+A+L +AGH+G+ Sbjct: 421 GTALTGTLVNQMYSSGVRDALSANHAAQWHARLADPQILIDRTAQGDLVAELTRAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEP 544 LLEAARE+LVGAIH+G+A+A + A+ +W RRVPPI +K+EP Sbjct: 481 LLLEAARESLVGAIHLGVAMAALVAVYSVWQCRRVPPIAL--RRKIEP 526 >B1FWS5.1 B1FWS5_9BURK Drug resistance transporter, EmrB/QacA subfamily Length = 531 Score = 743 bits (1918), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/530 (68%), Positives = 436/530 (82%), Gaps = 2/530 (0%) Query: 17 MALHTDSAHSSGQVLPFRESFLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 76 MA+HT + HSSGQVLPFRES LA LGI FV MLVALDQT+VGTALPTIVAELKGFELYAW Sbjct: 1 MAVHTAAHHSSGQVLPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAW 60 Query: 77 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 136 VAT+YLLTSVITVPIFGRLGDY+GRKPFVIASI+VF AS LCGMAN+MLFLVLARGLQG Sbjct: 61 VATSYLLTSVITVPIFGRLGDYYGRKPFVIASIVVFTAASVLCGMANNMLFLVLARGLQG 120 Query: 137 IGGGMLVGTCFASVADLFPDPRVRLRWQIILSVSFGIATAVGPSLGGFLTQGLGWRWVFY 196 IGGGMLVGT FA + DLFPD VRLRWQ+++S +FGIA AVGPSLGGFLTQ GWR VFY Sbjct: 121 IGGGMLVGTAFACIPDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFY 180 Query: 197 CNLPIGVISLFFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGVTS 256 NLP+G++SLFFVWRF+PH+RH++H GKMRLDWPGA LI+++LGSLQL VELLPK G+T Sbjct: 181 VNLPVGLLSLFFVWRFLPHLRHVEHEGKMRLDWPGAALIAVALGSLQLFVELLPKHGLTL 240 Query: 257 GMLVLLAVSVAAFYALWKWEQRAAQPILPFEMLRDRALASLFLLSVLAGFAMFSMLMYAP 316 LL +S A+ YALW+WE+R ILP +M R+ +LA+LF L+VL GF MFS+L YAP Sbjct: 241 SACALLVLSAASAYALWQWEKRCPTAILPVDMFRNPSLAALFTLAVLGGFTMFSLLFYAP 300 Query: 317 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGI 376 LLFQGGFG+SP+EAG++ITPLV IT+ SI NGR+++R+ NPNLM+ +GFALIA +C G+ Sbjct: 301 LLFQGGFGMSPKEAGVVITPLVVFITIGSIANGRVVSRVRNPNLMLYVGFALIALACFGV 360 Query: 377 VLCDRVTGKGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 436 V+ R L++ M+ GG GLG V+PNLT+FAQQ A REHLGIATALLQSLRMIGGM+ Sbjct: 361 VVATRSMPHWLLMSFMVLGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMI 420 Query: 437 GTAITGTLVSQMYGAGVEKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 496 GTA+TGTL+S MY +GV LE D A+QW D DP++L+NH+ Q+ LL +L QAGH+G+ Sbjct: 421 GTALTGTLISHMYASGVRSTLESDRASQWFSDLGDPQILINHEAQTTLLGELAQAGHNGA 480 Query: 497 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVRRVPPIRFDQDKKVEPVM 546 LLE ARE LV AIH G+A+A V A+V +W RRVPPI+ +K+EPV+ Sbjct: 481 MLLETARETLVSAIHFGLAMAAVVAVVSVWQSRRVPPIKL--QRKLEPVV 528