BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0045.p (222 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRN9.1 D8IRN9_HERSS Carboxylesterase protein EC=3.1.1.1 454 e-126 C5CTR8.1 C5CTR8_VARPS Carboxylesterase EC=3.1.1.1 314 5e-84 E6V767.1 E6V767_VARPD Phospholipase/Carboxylesterase 304 6e-81 E7S035.1 E7S035_9BURK Carboxylesterase EC=3.1.1.1 303 1e-80 Q127I1.1 Q127I1_POLSJ Carboxylesterase EC=3.1.1.1 297 6e-79 E3HEA0.1 E3HEA0_ACHXA Carboxylesterase EC=3.1.1.1 294 5e-78 A6SX24.1 A6SX24_JANMA Phospholipase/carboxylesterase 294 8e-78 A2SBS7.1 A2SBS7_METPP Carboxylesterase 292 2e-77 B1Y0E9.1 B1Y0E9_LEPCP Phospholipase/Carboxylesterase 291 6e-77 A1VLU4.1 A1VLU4_POLNA Phospholipase/Carboxylesterase 290 7e-77 >D8IRN9.1 D8IRN9_HERSS Carboxylesterase protein EC=3.1.1.1 Length = 222 Score = 454 bits (1169), Expect = e-126, Method: Compositional matrix adjust. Identities = 222/222 (100%), Positives = 222/222 (100%) Query: 1 MAAPLDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPV 60 MAAPLDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPV Sbjct: 1 MAAPLDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPV 60 Query: 61 TINGGYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQG 120 TINGGYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQG Sbjct: 61 TINGGYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQG 120 Query: 121 CAMTLQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERA 180 CAMTLQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERA Sbjct: 121 CAMTLQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERA 180 Query: 181 VKSRELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 VKSRELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA Sbjct: 181 VKSRELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 >C5CTR8.1 C5CTR8_VARPS Carboxylesterase EC=3.1.1.1 Length = 223 Score = 314 bits (805), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 150/214 (70%), Positives = 175/214 (81%) Query: 8 IQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTINGGYV 67 I+I+TAPNPTA+VI +HGLGADG+DFVPI ELDLS+ P+RF+FP AP +PVTINGGY Sbjct: 6 IEIETAPNPTATVIVMHGLGADGNDFVPIANELDLSSVGPVRFVFPNAPVIPVTINGGYR 65 Query: 68 MRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMTLQT 127 M AWYDI DLV REDE GLR SQAAIEALIA EKARG+ ANRIV+AGFSQGCAM L T Sbjct: 66 MPAWYDIAVADLVAREDEAGLRRSQAAIEALIASEKARGIAANRIVVAGFSQGCAMALMT 125 Query: 128 GLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSRELL 187 GLRH ERLAG++ LSGYLP+AAT AERHAANHDTP+F+AHG DPVV LE A++SR+ L Sbjct: 126 GLRHTERLAGIVGLSGYLPIAATTAAERHAANHDTPVFLAHGRQDPVVPLEAALRSRDAL 185 Query: 188 TQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVL 221 LG+ VEWH+Y M HSVC +E+ D+ +L VL Sbjct: 186 AALGYAVEWHEYTMAHSVCMDEIADLNRFLLHVL 219 >E6V767.1 E6V767_VARPD Phospholipase/Carboxylesterase Length = 220 Score = 304 bits (779), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 147/215 (68%), Positives = 173/215 (80%) Query: 8 IQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTINGGYV 67 I+I+TAPNPTASVI +HGLGADG+DFVPI ELDLS+ P+RF+FP AP +PVT+N GY Sbjct: 6 IEIETAPNPTASVILMHGLGADGNDFVPIAGELDLSSVGPVRFVFPNAPVIPVTLNNGYQ 65 Query: 68 MRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMTLQT 127 M AW+DI PD +ED GLR SQAAIEALIA EKARG+PA+RIV+AGFSQGCAM L T Sbjct: 66 MPAWFDIAGPDFNVQEDATGLRRSQAAIEALIANEKARGIPAHRIVVAGFSQGCAMALLT 125 Query: 128 GLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSRELL 187 GLRH ERLAG++ LSG+LPLAA+ AERHAANHDTP+F+ HG DP+V L RA +SR+ L Sbjct: 126 GLRHTERLAGIVGLSGWLPLAASTAAERHAANHDTPVFLGHGRQDPMVPLARATQSRDAL 185 Query: 188 TQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 LG+ VEWHDY M HSVC EEV D+ +L RVLA Sbjct: 186 IALGYTVEWHDYAMAHSVCMEEVADLNDFLLRVLA 220 >E7S035.1 E7S035_9BURK Carboxylesterase EC=3.1.1.1 Length = 221 Score = 303 bits (776), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 149/221 (67%), Positives = 172/221 (77%), Gaps = 2/221 (0%) Query: 1 MAAPLDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPV 60 M+ L+ ++ T P PTAS+I LHGLGADG+DFVP+ + LDL P+RFIFP AP MPV Sbjct: 1 MSQTLEALEFVTGPEPTASIIVLHGLGADGNDFVPVAQMLDLGV--PVRFIFPHAPQMPV 58 Query: 61 TINGGYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQG 120 TIN GYVMRAWYDI DL RREDE GLR SQAAIEALIA+E RG+PA RIVL GFSQG Sbjct: 59 TINNGYVMRAWYDILGTDLARREDEAGLRRSQAAIEALIAREVERGIPAERIVLMGFSQG 118 Query: 121 CAMTLQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERA 180 CAMTL TGLRH +RLA L+ LSGYLPLA + +ER A N +TPIFMAHG DPVVV+ERA Sbjct: 119 CAMTLMTGLRHKQRLAALVGLSGYLPLADSTASERSADNQNTPIFMAHGQDDPVVVIERA 178 Query: 181 VKSRELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVL 221 SR+LL LG+ V+WH+YPM HSVC EE+ DI A+L RVL Sbjct: 179 TASRDLLQSLGYTVDWHEYPMPHSVCPEEIGDIAAFLRRVL 219 >Q127I1.1 Q127I1_POLSJ Carboxylesterase EC=3.1.1.1 Length = 220 Score = 297 bits (761), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 142/218 (65%), Positives = 170/218 (77%) Query: 5 LDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTING 64 L+ ++ T NP A+++ +HGLGADG DFVPI +LDLS+ P+RF+FP+AP MPVTING Sbjct: 3 LEVLEAQTGNNPVATIVIMHGLGADGRDFVPIAEQLDLSSVGPVRFLFPSAPVMPVTING 62 Query: 65 GYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMT 124 GYVM AWYDI DL +REDE GLR SQA+IEAL+A EK+RG+PANRIV+AGFSQGCA+ Sbjct: 63 GYVMPAWYDILGADLAKREDEAGLRQSQASIEALLAHEKSRGIPANRIVVAGFSQGCALA 122 Query: 125 LQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSR 184 L TGLRH ERLAG+ LSGYLPLA AER AA+ PIF+AHG+ D VV L RA SR Sbjct: 123 LMTGLRHGERLAGIAGLSGYLPLADKTAAERSAASQGLPIFLAHGSHDGVVPLPRATASR 182 Query: 185 ELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 + LT LG+PVEWH+Y M+HSVC EEV D+ WL RVLA Sbjct: 183 DALTALGYPVEWHEYRMEHSVCPEEVVDLERWLRRVLA 220 >E3HEA0.1 E3HEA0_ACHXA Carboxylesterase EC=3.1.1.1 Length = 225 Score = 294 bits (753), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 147/224 (65%), Positives = 169/224 (75%), Gaps = 3/224 (1%) Query: 1 MAAP---LDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPT 57 M AP LD I+I+TAPNPT +VIWLHGLGADG+DF PIV ELDL A +RF+FP AP Sbjct: 1 MNAPTDLLDCIEIETAPNPTHAVIWLHGLGADGNDFAPIVPELDLPAGASVRFVFPNAPV 60 Query: 58 MPVTINGGYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGF 117 VTIN G MR+WYDI DLVR ED G+RAS+AAI LIA+E ARG+P +RIVLAGF Sbjct: 61 QRVTINNGMAMRSWYDILVMDLVRVEDAHGIRASEAAIHKLIARENARGIPTSRIVLAGF 120 Query: 118 SQGCAMTLQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVL 177 SQGCAMTL TG+R PE+LAG+M LSGYLPL T EAERH AN DTPIF+AHG DPVV L Sbjct: 121 SQGCAMTLHTGIRLPEKLAGMMGLSGYLPLLDTAEAERHGANQDTPIFLAHGQYDPVVSL 180 Query: 178 ERAVKSRELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVL 221 RA S L +LG+ V+WH YPM HSVC EEV D+ +L +VL Sbjct: 181 PRAQASLAELQRLGYDVQWHTYPMPHSVCAEEVADVSKFLNQVL 224 >A6SX24.1 A6SX24_JANMA Phospholipase/carboxylesterase Length = 220 Score = 294 bits (752), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 135/217 (62%), Positives = 169/217 (77%) Query: 5 LDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTING 64 L+T++I+TAPNPT S+IW+HGLGADG+DFVPIVRELDLS CP IRF+FP AP +PVT+NG Sbjct: 3 LETVEIETAPNPTVSIIWMHGLGADGNDFVPIVRELDLSGCPGIRFVFPHAPEIPVTVNG 62 Query: 65 GYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMT 124 M AWYD+ + R EDE GLRASQ +I LI +EKARG+ AN+I++AGFSQGCAMT Sbjct: 63 FREMPAWYDVVVTEFGREEDEAGLRASQVSINELIEREKARGIAANKILIAGFSQGCAMT 122 Query: 125 LQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSR 184 Q GLR+PERL GL+CLSGY+P+ +T+EAE AAN D PI+ HG D V+ + RA +S Sbjct: 123 FQVGLRYPERLGGLLCLSGYVPIDSTLEAEASAANKDIPIYYGHGRGDQVIPITRAQRSL 182 Query: 185 ELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVL 221 LL LG+ VEWH+Y M HSVCG +++DI +L RVL Sbjct: 183 SLLQALGYQVEWHEYNMPHSVCGPQLDDISNFLKRVL 219 >A2SBS7.1 A2SBS7_METPP Carboxylesterase Length = 248 Score = 292 bits (748), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 147/218 (67%), Positives = 164/218 (75%) Query: 5 LDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTING 64 LD I+I T +P AS+I LHGLGADG+DFVPI ELDL A RF+FP APT PVTING Sbjct: 31 LDCIEIQTTEHPAASIIVLHGLGADGNDFVPICEELDLDAVGGARFVFPHAPTRPVTING 90 Query: 65 GYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMT 124 GYVMRAWYDI PD RREDE GLRAS + ALI +E ARG+P++RIVLAGFSQGCAMT Sbjct: 91 GYVMRAWYDILGPDGPRREDEAGLRASLELVRALIERENARGIPSSRIVLAGFSQGCAMT 150 Query: 125 LQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSR 184 L TGLRH ERLAGL LSGYLPLA ER AAN D PIF+AHG DPV+ L RA SR Sbjct: 151 LLTGLRHGERLAGLAGLSGYLPLAPVTADERSAANADVPIFLAHGRADPVIPLARATASR 210 Query: 185 ELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 + L LG+ VEWH+YPM HSVC EE+ D+ WL RVLA Sbjct: 211 DALQALGYVVEWHEYPMPHSVCPEEIVDLNRWLLRVLA 248 >B1Y0E9.1 B1Y0E9_LEPCP Phospholipase/Carboxylesterase Length = 233 Score = 291 bits (744), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 135/218 (61%), Positives = 165/218 (75%) Query: 5 LDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTING 64 L+T+++ + PNP AS++ LHGLGADGSDFVPI +LDLSA +RF+FP AP PVT+NG Sbjct: 16 LETLELQSGPNPVASIVVLHGLGADGSDFVPIAEQLDLSAIGDVRFVFPDAPVRPVTVNG 75 Query: 65 GYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMT 124 GY MRAWYDIF DLVRREDE GLRAS A ++AL+ +E A G+ R VL GFSQGCAMT Sbjct: 76 GYQMRAWYDIFNADLVRREDEAGLRASLADVQALLDREAALGIAPQRTVLMGFSQGCAMT 135 Query: 125 LQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSR 184 L GLR P+RLAGL CLSGYLPLAA AER AAN D IFMAHG DP+V ++R + S Sbjct: 136 LLAGLRAPQRLAGLACLSGYLPLAARTAAERSAANQDVQIFMAHGRFDPIVTIDRGLASC 195 Query: 185 ELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 L LG+ ++W +YPM+HSVC EE++D+ WL +VLA Sbjct: 196 ATLAALGYAIDWREYPMEHSVCEEEIDDLNRWLLKVLA 233 >A1VLU4.1 A1VLU4_POLNA Phospholipase/Carboxylesterase Length = 220 Score = 290 bits (743), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 137/218 (62%), Positives = 167/218 (76%) Query: 5 LDTIQIDTAPNPTASVIWLHGLGADGSDFVPIVRELDLSACPPIRFIFPTAPTMPVTING 64 L I+ T NP A+++ +HGLGADG DFVPI +LDLS+ P+RF+FP+AP MPVTING Sbjct: 3 LQIIEAQTGENPVATILIMHGLGADGRDFVPIAEQLDLSSIGPVRFLFPSAPHMPVTING 62 Query: 65 GYVMRAWYDIFAPDLVRREDEPGLRASQAAIEALIAQEKARGVPANRIVLAGFSQGCAMT 124 GY M AWYDI DLV R+DE G+R +QA++EA+IA EKARG+ A+RIV+AGFSQGCAM Sbjct: 63 GYSMPAWYDILGADLVSRQDEAGMRQTQASMEAIIANEKARGIAASRIVVAGFSQGCAMA 122 Query: 125 LQTGLRHPERLAGLMCLSGYLPLAATIEAERHAANHDTPIFMAHGTMDPVVVLERAVKSR 184 L GLRH ERLAG+ LSGYLPLA AE AAN D PIF+AHG+ D VV L RAV +R Sbjct: 123 LMAGLRHKERLAGIAGLSGYLPLAEKTLAEGSAANKDVPIFLAHGSRDGVVALPRAVATR 182 Query: 185 ELLTQLGHPVEWHDYPMQHSVCGEEVEDIGAWLTRVLA 222 + LT +G+PVEWH+Y M+HSVC +EV D+ WL RVLA Sbjct: 183 DALTAMGYPVEWHEYLMEHSVCPQEVADLEKWLLRVLA 220