BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0026.p (771 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRL9.1 D8IRL9_HERSS DNA topoisomerase IV (Subunit A) protein E... 1566 0.0 A6SVU9.1 A6SVU9_JANMA Topoisomerase IV subunit A EC=5.99.1.- 1295 0.0 A4G394.1 A4G394_HERAR DNA topoisomerase 4 subunit A (Topoisomera... 1265 0.0 F1W2E6.1 F1W2E6_9BURK Topoisomerase IV subunit A 1238 0.0 E1TC50.1 E1TC50_BURSG DNA topoisomerase IV, A subunit EC=5.99.1.3 1136 0.0 E8YGW5.1 E8YGW5_9BURK DNA topoisomerase IV, A subunit EC=5.99.1.3 1111 0.0 D5NFP6.1 D5NFP6_9BURK DNA topoisomerase IV, A subunit EC=5.99.1.3 1110 0.0 Q142U4.1 Q142U4_BURXL DNA topoisomerase IV subunit A EC=5.99.1.3 1109 0.0 B1FXY5.1 B1FXY5_9BURK DNA topoisomerase IV, A subunit 1109 0.0 B2JE92.1 B2JE92_BURP8 DNA topoisomerase IV, A subunit 1107 0.0 >D8IRL9.1 D8IRL9_HERSS DNA topoisomerase IV (Subunit A) protein EC=5.99.1.- Length = 771 Score = 1566 bits (4056), Expect = 0.0, Method: Compositional matrix adjust. Identities = 771/771 (100%), Positives = 771/771 (100%) Query: 1 MTDQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 60 MTDQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA Sbjct: 1 MTDQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 60 Query: 61 MNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGS 120 MNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGS Sbjct: 61 MNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGS 120 Query: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGA 180 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGA Sbjct: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGA 180 Query: 181 SGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIA 240 SGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIA Sbjct: 181 SGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIA 240 Query: 241 EMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKS 300 EMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKS Sbjct: 241 EMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKS 300 Query: 301 LTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSAS 360 LTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSAS Sbjct: 301 LTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSAS 360 Query: 361 LNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNI 420 LNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNI Sbjct: 361 LNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNI 420 Query: 421 DKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKST 480 DKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKST Sbjct: 421 DKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKST 480 Query: 481 LQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGW 540 LQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGW Sbjct: 481 LQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGW 540 Query: 541 VRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVP 600 VRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVP Sbjct: 541 VRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVP 600 Query: 601 VTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGAL 660 VTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGAL Sbjct: 601 VTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGAL 660 Query: 661 PLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQ 720 PLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQ Sbjct: 661 PLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQ 720 Query: 721 KGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLRAQV 771 KGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLRAQV Sbjct: 721 KGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLRAQV 771 >A6SVU9.1 A6SVU9_JANMA Topoisomerase IV subunit A EC=5.99.1.- Length = 771 Score = 1295 bits (3350), Expect = 0.0, Method: Compositional matrix adjust. Identities = 623/770 (80%), Positives = 691/770 (89%) Query: 1 MTDQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 60 MTDQ LFDQ A GE+LTL+TFAERAYLDYAISVVKGRALPDV DGQKPVQRRIL+A Sbjct: 1 MTDQANLFDQEAPADGGEALTLTTFAERAYLDYAISVVKGRALPDVCDGQKPVQRRILFA 60 Query: 61 MNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGS 120 MNEL LNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDG GNFGS Sbjct: 61 MNELGLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 120 Query: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGA 180 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTV+FQPNYDGSTEEP+LLP+RLPF+LLNGA Sbjct: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVDFQPNYDGSTEEPKLLPSRLPFVLLNGA 180 Query: 181 SGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIA 240 SGIAVGMATEIPSHNL EVAKAAVA+IRNPK++H ELM ++PGPDFPGGGQIIT I+ Sbjct: 181 SGIAVGMATEIPSHNLHEVAKAAVALIRNPKLTHEELMAIVPGPDFPGGGQIITSPTAIS 240 Query: 241 EMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKS 300 ++Y SGRGS+KVRA WKIED+ARGQWQAV+TELP G SSQ+VLEEIEELTNPK+KLGKKS Sbjct: 241 DIYSSGRGSVKVRATWKIEDMARGQWQAVVTELPHGTSSQKVLEEIEELTNPKIKLGKKS 300 Query: 301 LTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSAS 360 L+PEQ A K +L +LD VRDESGRDAPVRLVFEPKSKNQDQTEF N LLA TSLETS S Sbjct: 301 LSPEQLALKQTVLSMLDTVRDESGRDAPVRLVFEPKSKNQDQTEFTNLLLAHTSLETSVS 360 Query: 361 LNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNI 420 +NLVMIGGDGRPRQK+L DIL EWI FRF T+TRR+QF++QKV+DRIHILEGREA+LLNI Sbjct: 361 INLVMIGGDGRPRQKSLGDILREWIEFRFTTITRRSQFKLQKVDDRIHILEGREAILLNI 420 Query: 421 DKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKST 480 DKVI+IIRESDEPKPAL++AFRLS+RQA+DILEIRLRQLARLE IKIQQELAELRNEK+T Sbjct: 421 DKVIKIIRESDEPKPALMDAFRLSERQADDILEIRLRQLARLETIKIQQELAELRNEKTT 480 Query: 481 LQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGW 540 LQDLLDNPSSMK+LVIKEIE D K +GDARRT+IE AE+A+ E KVIDEPVTV+ISQKGW Sbjct: 481 LQDLLDNPSSMKRLVIKEIEADEKQFGDARRTLIEVAEKASVETKVIDEPVTVVISQKGW 540 Query: 541 VRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVP 600 VRARTGHGHDA QFTFKAGD+LY FECRTVD+LL FGSNGR+Y++ V+ALP ARGDGVP Sbjct: 541 VRARTGHGHDAAQFTFKAGDTLYNTFECRTVDSLLVFGSNGRIYSVPVSALPGARGDGVP 600 Query: 601 VTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGAL 660 +TTL+ELASGS ILHYFAGPAD TLLLAS A GF AK+ DM R +GGKSF TLD+G Sbjct: 601 ITTLVELASGSRILHYFAGPADVTLLLASTAGYGFTAKSGDMVSRTRGGKSFITLDDGDE 660 Query: 661 PLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQ 720 PLAP PV ASA+AC+S GRLLVFG+DE+K+L++GGRGV LM+LEKNEKL+AAQAISQ Sbjct: 661 PLAPCPVTAGASAIACLSEKGRLLVFGIDEIKSLTAGGRGVILMDLEKNEKLLAAQAISQ 720 Query: 721 KGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLRAQ 770 +GV+V G G GKA+E+ LSA LA HIGKRARKGKALES+IK T L AQ Sbjct: 721 RGVIVSGAGRGGKAQEVLLSASGLAPHIGKRARKGKALESKIKATTLTAQ 770 >A4G394.1 A4G394_HERAR DNA topoisomerase 4 subunit A (Topoisomerase IV subunit A) EC=5.99.1.- Length = 776 Score = 1265 bits (3273), Expect = 0.0, Method: Compositional matrix adjust. Identities = 606/767 (79%), Positives = 680/767 (88%) Query: 1 MTDQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYA 60 MTDQ LFD A GESLTL+TFAERAYLDYAISVVKGRALPDV DGQKPVQRRIL+A Sbjct: 1 MTDQANLFDTAAPADGGESLTLATFAERAYLDYAISVVKGRALPDVCDGQKPVQRRILFA 60 Query: 61 MNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGS 120 MNEL LNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDG GNFGS Sbjct: 61 MNELGLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGQGNFGS 120 Query: 121 RDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGA 180 RDGDGAAAMRYTEARLTPI+KLL++EIDMGTV+FQPNYDGSTEEP+LLP+RLPF+LLNGA Sbjct: 121 RDGDGAAAMRYTEARLTPIAKLLMEEIDMGTVDFQPNYDGSTEEPKLLPSRLPFVLLNGA 180 Query: 181 SGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIA 240 SGIAVGMATEIPSHNL EVA+AAVA+IRNPK++H EL+ ++PGPDFPGGGQIIT I+ Sbjct: 181 SGIAVGMATEIPSHNLREVAQAAVALIRNPKLTHEELVAIVPGPDFPGGGQIITSPTAIS 240 Query: 241 EMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKS 300 ++Y+SGRGS+KVRA WKIED+ARGQWQAV+TELP G SSQRVLEEIEELTNPK++LGKKS Sbjct: 241 DIYRSGRGSVKVRATWKIEDMARGQWQAVVTELPHGTSSQRVLEEIEELTNPKIRLGKKS 300 Query: 301 LTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSAS 360 L+PEQ A K +L +LD VRDESGRDAPVRLVFEPKSKNQDQTEF N LLA TSLETS S Sbjct: 301 LSPEQLALKQTVLAMLDTVRDESGRDAPVRLVFEPKSKNQDQTEFTNMLLAHTSLETSVS 360 Query: 361 LNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNI 420 +NLVMIGGDG+PRQK L DIL EW+ FRF T+TRR+QF++QKVNDRIHILEGREA+LLNI Sbjct: 361 INLVMIGGDGKPRQKALGDILREWVDFRFTTITRRSQFKLQKVNDRIHILEGREAILLNI 420 Query: 421 DKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKST 480 DKVI+IIRESDEPKPAL++AFRLS+RQA+DILEIRLRQLARLE IKIQQELAELR+EKST Sbjct: 421 DKVIKIIRESDEPKPALMDAFRLSERQADDILEIRLRQLARLETIKIQQELAELRSEKST 480 Query: 481 LQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGW 540 LQDLLDNPSSMK+LVIKEIE D K +GD RRT+IE AE+A E +VIDEPVTV+ISQKGW Sbjct: 481 LQDLLDNPSSMKRLVIKEIEADEKQFGDKRRTLIEVAEKAVVETRVIDEPVTVVISQKGW 540 Query: 541 VRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVP 600 VRARTGHGHDA QFTFKA D+LY FECRTVD LL FGSNGR+Y++AV ALP ARGDGVP Sbjct: 541 VRARTGHGHDAAQFTFKASDALYDTFECRTVDTLLVFGSNGRIYSVAVAALPGARGDGVP 600 Query: 601 VTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGAL 660 +TTL+ELASG+ +LHYFAGPAD TLLLAS A GF AK+ DM R + GK+F TLDEG Sbjct: 601 ITTLVELASGTRVLHYFAGPADVTLLLASTAGYGFTAKSGDMVSRTRSGKAFITLDEGDE 660 Query: 661 PLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQ 720 PL P P+ ASA+AC+S GR+LVFG+DE+K+L++GGRGV LM+LEKNEKL+AAQ ISQ Sbjct: 661 PLTPRPIFAGASAIACLSEKGRVLVFGIDEIKSLTAGGRGVILMDLEKNEKLLAAQPISQ 720 Query: 721 KGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGL 767 +GVVV G G KA+EI LSA LA+HIGKRARKGK LES+IK T L Sbjct: 721 RGVVVSGIGRGAKAQEILLSASGLAVHIGKRARKGKGLESKIKATTL 767 >F1W2E6.1 F1W2E6_9BURK Topoisomerase IV subunit A Length = 772 Score = 1238 bits (3202), Expect = 0.0, Method: Compositional matrix adjust. Identities = 602/771 (78%), Positives = 682/771 (88%), Gaps = 3/771 (0%) Query: 1 MTDQPTLFD-QVPSAPDG-ESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRIL 58 MT+Q TLFD P PDG E+LTL+TFAERAYLDYAISVVKGRALPDV+DGQKPVQRRIL Sbjct: 1 MTEQATLFDGDTPEPPDGAETLTLATFAERAYLDYAISVVKGRALPDVSDGQKPVQRRIL 60 Query: 59 YAMNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNF 118 +AMN+L LN+AAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQ FSLRYPLIDG GNF Sbjct: 61 FAMNQLGLNAAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQGFSLRYPLIDGQGNF 120 Query: 119 GSRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLN 178 GSRDGDGAAAMRYTEARLTPIS LLLDEID+GTV+FQPNYDGSTEEP LLP RLPF+LLN Sbjct: 121 GSRDGDGAAAMRYTEARLTPISSLLLDEIDLGTVDFQPNYDGSTEEPSLLPGRLPFVLLN 180 Query: 179 GASGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQAT 238 GASGIAVGMATEIPSHNL EVA+AAVA+IRNP ++HAELM +IPGPDFP GGQIIT A Sbjct: 181 GASGIAVGMATEIPSHNLREVAQAAVALIRNPALTHAELMAIIPGPDFPSGGQIITSAAA 240 Query: 239 IAEMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGK 298 ++EMY +GRGSLKVRA WKIE++ARGQWQAV+TELP G S+Q+VLEEIEELTNPK+KLGK Sbjct: 241 LSEMYANGRGSLKVRALWKIEEMARGQWQAVVTELPHGTSAQKVLEEIEELTNPKIKLGK 300 Query: 299 KSLTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETS 358 K+L+P+Q AQK +L LLDAVRDESGR+APVRLVFEPKSKNQDQTEF N LLAQTSLETS Sbjct: 301 KALSPDQLAQKQLMLSLLDAVRDESGREAPVRLVFEPKSKNQDQTEFTNMLLAQTSLETS 360 Query: 359 ASLNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLL 418 AS+NLVMIGGDGRPRQK L DIL EWI+FRF+TVTRR+ FR++KV DRIHILEGRE +LL Sbjct: 361 ASINLVMIGGDGRPRQKGLGDILREWIAFRFDTVTRRSHFRLKKVEDRIHILEGRETILL 420 Query: 419 NIDKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEK 478 NID+VIRIIRESDEPKPAL+ AF+LSDRQAEDILEIRLRQLARLEAIKIQQELA LR EK Sbjct: 421 NIDEVIRIIRESDEPKPALMGAFKLSDRQAEDILEIRLRQLARLEAIKIQQELAGLRTEK 480 Query: 479 STLQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQK 538 STL++LL+NP +MKKL+IKEI+ D K +GDARRT+IE AERAT EQKVIDEPVTV+ISQK Sbjct: 481 STLEELLNNPGAMKKLIIKEIDADEKRFGDARRTLIEAAERATVEQKVIDEPVTVVISQK 540 Query: 539 GWVRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDG 598 GW+RARTGHGHD QF FKAGD LY FECRT+D+LLAFGSNGR+Y+IAV++LP ARGDG Sbjct: 541 GWLRARTGHGHDPAQFAFKAGDDLYRTFECRTLDSLLAFGSNGRIYSIAVSSLPGARGDG 600 Query: 599 VPVTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEG 658 P++ L+ELASGS++LHYFAG AD+T+LLAS A GFIA+A+DM GR K GK+F TLD G Sbjct: 601 APISALVELASGSTVLHYFAGSADSTMLLASTAGYGFIARAADMIGRNKAGKAFITLDAG 660 Query: 659 ALPLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAI 718 LPL P + AS+VAC+SG GRLLVFGLDE+KT+ SGGRG+ LM LE EKL+AAQ + Sbjct: 661 DLPLPPQMLIPSASSVACLSGEGRLLVFGLDELKTM-SGGRGMILMALEDGEKLLAAQPV 719 Query: 719 SQKGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLRA 769 SQ+GV+V G G GK +E++LSA LALH GKRARKGKALES++K L A Sbjct: 720 SQRGVLVSGIGRGGKTQEVSLSATGLALHTGKRARKGKALESKLKPHTLTA 770 >E1TC50.1 E1TC50_BURSG DNA topoisomerase IV, A subunit EC=5.99.1.3 Length = 774 Score = 1136 bits (2939), Expect = 0.0, Method: Compositional matrix adjust. Identities = 557/770 (72%), Positives = 642/770 (83%), Gaps = 3/770 (0%) Query: 1 MTDQPTL--FDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRIL 58 M D TL F + P AP+G+ LTL +AE AYL YA+SVVKGRALPDV DGQKPVQRRIL Sbjct: 1 MDDDNTLDLFTE-PPAPEGDFLTLGNYAEGAYLQYAVSVVKGRALPDVCDGQKPVQRRIL 59 Query: 59 YAMNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNF 118 YAMNEL L+ AKP KSA VVGDV+GK HPHGDQS YDALVR+AQDF++RYPLIDG GNF Sbjct: 60 YAMNELGLSDNAKPVKSARVVGDVIGKYHPHGDQSAYDALVRLAQDFAMRYPLIDGQGNF 119 Query: 119 GSRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLN 178 GSRDGDGAAAMRYTEARLTPISKLLLDEID GTV+F PNYDG EEPR LPARLPFLLLN Sbjct: 120 GSRDGDGAAAMRYTEARLTPISKLLLDEIDQGTVDFMPNYDGVEEEPRQLPARLPFLLLN 179 Query: 179 GASGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQAT 238 GASGIAVG+ATEIPSHNL EVA A VAMIRNPKI+HAELM+ +PGPDFPGGGQII+ +A Sbjct: 180 GASGIAVGLATEIPSHNLREVAAATVAMIRNPKIAHAELMQHLPGPDFPGGGQIISSEAE 239 Query: 239 IAEMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGK 298 IA Y++GRGSLKVRARWKIEDLARGQWQ VITELPP ++Q+VLEEIEE TNPK+KLGK Sbjct: 240 IAAAYETGRGSLKVRARWKIEDLARGQWQLVITELPPNTAAQKVLEEIEEQTNPKIKLGK 299 Query: 299 KSLTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETS 358 K+LTPEQ K +LGLLDAVRDESG+DAPVRLVFEPKS DQTEF+NTLLA TSLE++ Sbjct: 300 KALTPEQLQAKQTMLGLLDAVRDESGKDAPVRLVFEPKSSRIDQTEFVNTLLAHTSLESN 359 Query: 359 ASLNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLL 418 ASLNLVM+GGDGRPRQK L++IL EWI+FRF TVTRRT+ R+ KV+DRIHILEGR V L Sbjct: 360 ASLNLVMVGGDGRPRQKGLSEILHEWIAFRFATVTRRTRHRLTKVDDRIHILEGRMIVYL 419 Query: 419 NIDKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEK 478 NID+VIRIIRESDEPK AL+ AF LSDRQA+DILEIRLRQLARLE IKI++ELAELR+EK Sbjct: 420 NIDEVIRIIRESDEPKVALMAAFGLSDRQADDILEIRLRQLARLEKIKIEKELAELRDEK 479 Query: 479 STLQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQK 538 + L++LL + S+MK+L+IKEIE DAK YGD RRT+I++ +RAT+E +VIDEPVTV++SQK Sbjct: 480 AKLEELLGSESAMKRLLIKEIEADAKQYGDERRTLIQQEKRATYEARVIDEPVTVVVSQK 539 Query: 539 GWVRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDG 598 GWVRA GHG D FTFKAGD LY AF+CRT D L+A+GSNGRVY++AV +LP RGDG Sbjct: 540 GWVRALKGHGLDTAGFTFKAGDGLYAAFQCRTPDTLVAWGSNGRVYSVAVASLPGGRGDG 599 Query: 599 VPVTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEG 658 VPVT+L+EL SGS ++HY+A AD LLLAS GFIAK DM RVK GKSF T+D G Sbjct: 600 VPVTSLIELESGSHLMHYYAASADQALLLASSNGFGFIAKVGDMVSRVKAGKSFMTIDAG 659 Query: 659 ALPLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAI 718 A+PLAP P+ DAS VAC+S GRLLVFG+DEMKTLS GGRGV LM L+ E LV A AI Sbjct: 660 AVPLAPMPLLPDASQVACLSSTGRLLVFGIDEMKTLSGGGRGVTLMALDDKETLVQALAI 719 Query: 719 SQKGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLR 768 + GV++ G G+ E LS +LA H+GKRARKG+A ES++K+ G+R Sbjct: 720 NGAGVMLIGARRGGRLDEEKLSGAALAAHVGKRARKGRAPESKLKLEGMR 769 >E8YGW5.1 E8YGW5_9BURK DNA topoisomerase IV, A subunit EC=5.99.1.3 Length = 774 Score = 1111 bits (2873), Expect = 0.0, Method: Compositional matrix adjust. Identities = 553/770 (71%), Positives = 638/770 (82%), Gaps = 3/770 (0%) Query: 1 MTDQPTL--FDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRIL 58 M D TL F + P P+G+ LTL +AE AYL YA+SVVKGRALPDV DGQKPVQRRIL Sbjct: 1 MDDDNTLDLFTE-PPPPEGDFLTLGNYAEGAYLQYAVSVVKGRALPDVCDGQKPVQRRIL 59 Query: 59 YAMNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNF 118 YAMNEL L+ AKP KSA VVGDV+GK HPHGDQS YDALVR+AQDF++RYPLIDG GNF Sbjct: 60 YAMNELGLSDNAKPVKSARVVGDVIGKYHPHGDQSAYDALVRLAQDFAMRYPLIDGQGNF 119 Query: 119 GSRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLN 178 GSRDGDGAAAMRYTEARLTPISKLLLDEID GTV+F PNYDG +EPR LPARLPFLLLN Sbjct: 120 GSRDGDGAAAMRYTEARLTPISKLLLDEIDQGTVDFMPNYDGVEQEPRQLPARLPFLLLN 179 Query: 179 GASGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQAT 238 GASGIAVG+ATEIPSHNL EVA A VAMIRNPKI+HA+LM+ +PGPDFPGGGQII+ +A Sbjct: 180 GASGIAVGLATEIPSHNLREVAAATVAMIRNPKIAHADLMQHMPGPDFPGGGQIISSEAE 239 Query: 239 IAEMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGK 298 IA Y+SGRGSLKVRARWKIEDLARGQWQ VITELPP ++Q+VLEEIEE TNPK+KLGK Sbjct: 240 IAAAYESGRGSLKVRARWKIEDLARGQWQLVITELPPNTAAQKVLEEIEEQTNPKIKLGK 299 Query: 299 KSLTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETS 358 K+LTPEQ K +L LLDAVRDESG+DAPVRLVFEPKS DQTEF+NTLLA TSLE++ Sbjct: 300 KALTPEQLQAKQTMLSLLDAVRDESGKDAPVRLVFEPKSSRIDQTEFVNTLLAHTSLESN 359 Query: 359 ASLNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLL 418 ASLNLVM+GGDGRPRQK L++IL EWI+FRF TVTRRT+ R+ KV+DRIHILEGR V L Sbjct: 360 ASLNLVMVGGDGRPRQKGLSEILHEWIAFRFATVTRRTRHRLTKVDDRIHILEGRMIVYL 419 Query: 419 NIDKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEK 478 NID+VIRIIRESDEPK AL+ AF LSDRQA+DILEIRLRQLARLE IKI++ELA+LR+EK Sbjct: 420 NIDEVIRIIRESDEPKVALMAAFGLSDRQADDILEIRLRQLARLEKIKIEKELADLRDEK 479 Query: 479 STLQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQK 538 + L++LL + S+MK+L+IKEIE DAK YGD RRT+I++ +RAT+E +VIDEPVTV++SQK Sbjct: 480 AKLEELLASESAMKRLLIKEIEADAKQYGDERRTLIQQEKRATYEARVIDEPVTVVVSQK 539 Query: 539 GWVRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDG 598 GWVRA GHG D FTFKAGD LY AF CRT D L+A+GSNGRVY++AV +LP RGDG Sbjct: 540 GWVRALKGHGLDTAGFTFKAGDGLYAAFPCRTPDTLIAWGSNGRVYSVAVASLPGGRGDG 599 Query: 599 VPVTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEG 658 VPVT+L+EL SGS ++HY+A AD LLLAS GFIAK DM RVK GKSF T+D G Sbjct: 600 VPVTSLIELESGSHLMHYYAAAADQALLLASSNGFGFIAKVGDMVSRVKAGKSFMTIDAG 659 Query: 659 ALPLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAI 718 A PLAP P+ DAS VAC+S GRLLVFG+DEMKTLS GGRGV LM L+ E LV A AI Sbjct: 660 AAPLAPMPMLPDASQVACLSSTGRLLVFGIDEMKTLSGGGRGVTLMALDDKETLVQALAI 719 Query: 719 SQKGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLR 768 + GV++ G G+ E LS +LA H+GKRARKG+A ES++K+ G+R Sbjct: 720 NGAGVMLIGARRGGRLDEEKLSGAALAAHVGKRARKGRAPESKLKLEGMR 769 >D5NFP6.1 D5NFP6_9BURK DNA topoisomerase IV, A subunit EC=5.99.1.3 Length = 774 Score = 1110 bits (2870), Expect = 0.0, Method: Compositional matrix adjust. Identities = 552/769 (71%), Positives = 640/769 (83%), Gaps = 1/769 (0%) Query: 1 MTDQPTL-FDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILY 59 M D TL P P+G+ LTL +AERAYLDYA+SVVKGRALPDV DGQKPVQRRIL+ Sbjct: 1 MDDDNTLDLFTAPPPPEGDFLTLGNYAERAYLDYAVSVVKGRALPDVCDGQKPVQRRILF 60 Query: 60 AMNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFG 119 AMN++ L+ AKP KSA VVGDVLGK HPHGDQS YDALVR+AQDFS+RYPLIDG GNFG Sbjct: 61 AMNDMGLSDNAKPVKSARVVGDVLGKYHPHGDQSAYDALVRLAQDFSMRYPLIDGQGNFG 120 Query: 120 SRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNG 179 SRDGDGAAAMRYTEARLTPI+KLLLDEI+ GTV+F NYDG +EPRLLPARLPF+LLNG Sbjct: 121 SRDGDGAAAMRYTEARLTPIAKLLLDEINQGTVDFMKNYDGEFDEPRLLPARLPFVLLNG 180 Query: 180 ASGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATI 239 ASGIAVG+ATEIPSHNL EVA AAVAMIRNPK+ HAELM+ IPGPDFPGGGQII+ +A I Sbjct: 181 ASGIAVGLATEIPSHNLREVAAAAVAMIRNPKLQHAELMQYIPGPDFPGGGQIISSEAEI 240 Query: 240 AEMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKK 299 + Y+SGRGSLKVRARWKIE+LARGQWQ VITELPP ++Q+VLEEIEE TNPK+KLGKK Sbjct: 241 SAAYESGRGSLKVRARWKIEELARGQWQLVITELPPSTAAQKVLEEIEEQTNPKIKLGKK 300 Query: 300 SLTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSA 359 +LTPEQ K +L LLDAVRDESG+DAPVRLVFEPKS DQT+F+NTLLA TSLE++A Sbjct: 301 TLTPEQLQTKQTMLALLDAVRDESGKDAPVRLVFEPKSSRIDQTDFVNTLLAHTSLESNA 360 Query: 360 SLNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLN 419 SLNLVM+GGDGRPRQK L++IL EWI+FRF TVTRRT+ R+ KV+DRIHILEGR V LN Sbjct: 361 SLNLVMVGGDGRPRQKGLSEILHEWIAFRFATVTRRTRHRLSKVDDRIHILEGRMIVFLN 420 Query: 420 IDKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKS 479 ID+VIRIIRESDEPK AL+ AF LSDRQAEDILEIRLRQLARLE IKI++ELAEL++EK+ Sbjct: 421 IDEVIRIIRESDEPKVALMAAFGLSDRQAEDILEIRLRQLARLEKIKIEKELAELKDEKA 480 Query: 480 TLQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKG 539 L++LL + S+MK+L+IKEIEGDAK YGD RRT+I++ +RATFE +V+DEPVTV++SQKG Sbjct: 481 RLEELLGSESAMKRLLIKEIEGDAKQYGDERRTLIQQEKRATFEARVVDEPVTVVVSQKG 540 Query: 540 WVRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGV 599 WVRA GHG DA FTFKAGD LY AF+CRT D L+A+GSNGRVY++AV LP RGDGV Sbjct: 541 WVRALKGHGLDAAGFTFKAGDGLYAAFQCRTPDTLVAWGSNGRVYSVAVAMLPGGRGDGV 600 Query: 600 PVTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGA 659 PVT+L+EL SGS ++HY+A AD LLLAS GFIAK DM RVK GKSF T+D GA Sbjct: 601 PVTSLIELESGSHLMHYYAASADQALLLASSNGFGFIAKVGDMVSRVKAGKSFMTIDAGA 660 Query: 660 LPLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAIS 719 PLAP P+ DA+ +AC+S NGRLLVFGLDEMKTLS GGRGV LM L+ E LV A +I+ Sbjct: 661 QPLAPMPMLPDATHIACLSSNGRLLVFGLDEMKTLSGGGRGVTLMALDDEETLVQALSIN 720 Query: 720 QKGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLR 768 GVV+ GT G+ E +S LA HIGKRARKG+A ES++K+ +R Sbjct: 721 NAGVVLIGTRRGGRVDEEKVSGAVLAPHIGKRARKGRAPESKMKLESMR 769 >Q142U4.1 Q142U4_BURXL DNA topoisomerase IV subunit A EC=5.99.1.3 Length = 774 Score = 1109 bits (2869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 552/770 (71%), Positives = 644/770 (83%), Gaps = 3/770 (0%) Query: 1 MTDQPTL--FDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRIL 58 M D TL F + P P+G+ LTL +AERAYLDYA+SVVKGRALPDV DGQKPVQRRIL Sbjct: 1 MDDDNTLDLFTE-PPPPEGDFLTLGNYAERAYLDYAVSVVKGRALPDVCDGQKPVQRRIL 59 Query: 59 YAMNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNF 118 +AMN++ L+ AKP KSA VVGDVLGK HPHGDQS YDALVR+AQDFS+RYPLIDG GNF Sbjct: 60 FAMNDMGLSDNAKPVKSARVVGDVLGKYHPHGDQSAYDALVRLAQDFSMRYPLIDGQGNF 119 Query: 119 GSRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLN 178 GSRDGDGAAAMRYTEARLTPI+KLLLDEI+ GTV+F NYDG +EPRLLPARLPF+LLN Sbjct: 120 GSRDGDGAAAMRYTEARLTPIAKLLLDEINQGTVDFMKNYDGEFDEPRLLPARLPFVLLN 179 Query: 179 GASGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQAT 238 GASGIAVG+ATEIPSHNL EVA AAVAMIRNPK+ HAELM+ IPGPDFPGGGQII+ +A Sbjct: 180 GASGIAVGLATEIPSHNLREVAAAAVAMIRNPKLQHAELMQYIPGPDFPGGGQIISSEAE 239 Query: 239 IAEMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGK 298 I+ Y+SGRGSLKVRARWKIE+LARGQWQ VITELPP ++Q+VLEEIEE TNPK+KLGK Sbjct: 240 ISAAYESGRGSLKVRARWKIEELARGQWQLVITELPPSTAAQKVLEEIEEQTNPKIKLGK 299 Query: 299 KSLTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETS 358 K+LTPEQ K +L LLDAVRDESG+DAPVRLVFEPKS DQT+F+NTLLA TSLE++ Sbjct: 300 KTLTPEQLQTKQTMLALLDAVRDESGKDAPVRLVFEPKSSRIDQTDFVNTLLAHTSLESN 359 Query: 359 ASLNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLL 418 ASLNLVM+GGDGRPRQK L++IL EWI+FRF TVTRRT+ R+ KV+DRIHILEGR V L Sbjct: 360 ASLNLVMVGGDGRPRQKGLSEILHEWIAFRFATVTRRTRHRLSKVDDRIHILEGRMIVFL 419 Query: 419 NIDKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEK 478 NID+VIRIIRESDEPK AL+ AF LSDRQAEDILEIRLRQLARLE IKI++ELAEL++EK Sbjct: 420 NIDEVIRIIRESDEPKVALMAAFGLSDRQAEDILEIRLRQLARLEKIKIEKELAELKDEK 479 Query: 479 STLQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQK 538 + L++LL + S+MK+L+IKEIEGDAK YGD RRT+I++ +RATFE +V+DEPVTV++SQK Sbjct: 480 ARLEELLGSESAMKRLLIKEIEGDAKQYGDERRTLIQQEKRATFEARVVDEPVTVVVSQK 539 Query: 539 GWVRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDG 598 GWVRA GHG DA FTFKAGD LY AF+CRT D L+A+GSNGRVY++AV LP RGDG Sbjct: 540 GWVRALKGHGLDAAGFTFKAGDGLYAAFQCRTPDTLVAWGSNGRVYSVAVAMLPGGRGDG 599 Query: 599 VPVTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEG 658 VPVT+L+EL SGS ++HY+A AD LLLAS GFIA+ DM RVK GKSF T+D G Sbjct: 600 VPVTSLIELESGSHLMHYYAASADQALLLASSNGFGFIARVGDMVSRVKAGKSFMTIDAG 659 Query: 659 ALPLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAI 718 A PLAP P+ DA+ +AC+S NGRLLVFGLDEMKTLS GGRGV LM L++ E LV A +I Sbjct: 660 AQPLAPMPMLPDATHIACLSSNGRLLVFGLDEMKTLSGGGRGVTLMALDEKETLVQALSI 719 Query: 719 SQKGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLR 768 + GVV+ GT G+ E +S +LA HIGKRARKG+A ES++K+ +R Sbjct: 720 NNAGVVLIGTRRGGRVDEEKVSGAALAPHIGKRARKGRAPESKMKLESMR 769 >B1FXY5.1 B1FXY5_9BURK DNA topoisomerase IV, A subunit Length = 774 Score = 1109 bits (2868), Expect = 0.0, Method: Compositional matrix adjust. Identities = 550/770 (71%), Positives = 642/770 (83%), Gaps = 3/770 (0%) Query: 1 MTDQPTL--FDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRIL 58 M D TL F + P P+G+ LTL +AERAYLDYA+SVVKGRALPDV DGQKPVQRRIL Sbjct: 1 MDDDNTLDLFTE-PPPPEGDFLTLGNYAERAYLDYAVSVVKGRALPDVCDGQKPVQRRIL 59 Query: 59 YAMNELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNF 118 +AMN++ L+ AKP KSA VVGDVLGK HPHGDQS YDALVR+AQDFS+RYPLIDG GNF Sbjct: 60 FAMNDMGLSDNAKPVKSARVVGDVLGKYHPHGDQSAYDALVRLAQDFSMRYPLIDGQGNF 119 Query: 119 GSRDGDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLN 178 GSRDGDGAAAMRYTEARLTPI+KLLL EID GTV+F NYDG +EPRLLPARLPF+LLN Sbjct: 120 GSRDGDGAAAMRYTEARLTPIAKLLLAEIDQGTVDFMKNYDGEFDEPRLLPARLPFVLLN 179 Query: 179 GASGIAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQAT 238 GASGIAVG+ATEIPSHNL EVA A VAMIRNPKI+HAELME +PGPDFPGGGQII+ +A Sbjct: 180 GASGIAVGLATEIPSHNLREVAAATVAMIRNPKITHAELMEHVPGPDFPGGGQIISSEAE 239 Query: 239 IAEMYQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGK 298 I+ Y++GRGSLKVRARWKIEDLARGQWQ VITELPP ++Q+VLEEIEE TNPK+KLGK Sbjct: 240 ISAAYETGRGSLKVRARWKIEDLARGQWQLVITELPPNTAAQKVLEEIEEQTNPKIKLGK 299 Query: 299 KSLTPEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETS 358 K+LTPEQ K +LGLLDAVRDESG+DAPVRLVFEPKS DQTEF+NTLLA TSLE++ Sbjct: 300 KALTPEQLQGKQTMLGLLDAVRDESGKDAPVRLVFEPKSSRIDQTEFVNTLLAHTSLESN 359 Query: 359 ASLNLVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLL 418 ASLN+VM+GGDGRPRQK L++IL EWI+FRF TVTRRT+ R+ KV+DRIHILEGR V L Sbjct: 360 ASLNMVMVGGDGRPRQKGLSEILHEWIAFRFATVTRRTRHRLTKVDDRIHILEGRMIVFL 419 Query: 419 NIDKVIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEK 478 NID+VIRIIRESDEPK AL+ AF LSDRQAEDILEIRLRQLARLE IKI++ELAELR+EK Sbjct: 420 NIDEVIRIIRESDEPKVALMAAFGLSDRQAEDILEIRLRQLARLEKIKIEKELAELRDEK 479 Query: 479 STLQDLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQK 538 + L++LL + S+MK+L+IKE+E DAK YGD RRT+I++ +RAT+E +V+DEPVTV++SQK Sbjct: 480 AKLEELLGSESAMKRLLIKEVEADAKQYGDERRTLIQQEKRATYEARVVDEPVTVVVSQK 539 Query: 539 GWVRARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDG 598 GWVRA GHG D FTFKAGDSLY AF+CRT D L+A+GSNGRVY++AV +LP RGDG Sbjct: 540 GWVRALKGHGLDTAGFTFKAGDSLYAAFQCRTPDTLIAWGSNGRVYSVAVASLPGGRGDG 599 Query: 599 VPVTTLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEG 658 VPVT+L+E+ SGS ++HY+A AD LLLAS GFIAK DM RVK GKSF T+D G Sbjct: 600 VPVTSLIEMESGSHLMHYYAASADQALLLASSNGFGFIAKVGDMVSRVKAGKSFMTIDAG 659 Query: 659 ALPLAPTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAI 718 A PLAP P+ DA+ VAC+S GRLLVFG+DEMKTLS GGRGV LM L+ E LV A AI Sbjct: 660 AAPLAPMPMLPDATQVACLSSAGRLLVFGIDEMKTLSGGGRGVTLMALDDKETLVQALAI 719 Query: 719 SQKGVVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIKVTGLR 768 + GV++ G G+ E LS +LA H+GKRARKG+A ES++K+ G+R Sbjct: 720 NAAGVMLIGARRGGRLDEEKLSGAALAAHVGKRARKGRAPESKLKLEGMR 769 >B2JE92.1 B2JE92_BURP8 DNA topoisomerase IV, A subunit Length = 773 Score = 1107 bits (2864), Expect = 0.0, Method: Compositional matrix adjust. Identities = 553/767 (72%), Positives = 643/767 (83%), Gaps = 3/767 (0%) Query: 3 DQPTLFDQVPSAPDGESLTLSTFAERAYLDYAISVVKGRALPDVADGQKPVQRRILYAMN 62 + P LF + P+AP+G+ LTL +AERAYLDYA+SVVKGRALPDV DGQKPVQRRILYAMN Sbjct: 4 NTPDLFTE-PAAPEGDVLTLGNYAERAYLDYAVSVVKGRALPDVCDGQKPVQRRILYAMN 62 Query: 63 ELSLNSAAKPRKSAAVVGDVLGKLHPHGDQSVYDALVRMAQDFSLRYPLIDGHGNFGSRD 122 E+ L AKP KSA VVGDVLGK HPHGDQS YDALVR+AQDFS+RYPLIDG GNFGSRD Sbjct: 63 EMGLGDNAKPVKSARVVGDVLGKYHPHGDQSAYDALVRLAQDFSMRYPLIDGQGNFGSRD 122 Query: 123 GDGAAAMRYTEARLTPISKLLLDEIDMGTVEFQPNYDGSTEEPRLLPARLPFLLLNGASG 182 GDGAAAMRYTEARLTPI+KLLLDEID GTV+F PNYDGS EEP+LLPARLPF+LLNGASG Sbjct: 123 GDGAAAMRYTEARLTPIAKLLLDEIDQGTVDFMPNYDGSFEEPKLLPARLPFVLLNGASG 182 Query: 183 IAVGMATEIPSHNLTEVAKAAVAMIRNPKISHAELMELIPGPDFPGGGQIITPQATIAEM 242 IAVG+ATEIPSHNL EVA AAVAMIR+PKI+HAELM+L+PGPDFPGGGQII+ +A I++ Sbjct: 183 IAVGLATEIPSHNLREVAAAAVAMIRHPKITHAELMQLVPGPDFPGGGQIISSEAEISQA 242 Query: 243 YQSGRGSLKVRARWKIEDLARGQWQAVITELPPGVSSQRVLEEIEELTNPKVKLGKKSLT 302 Y++GRGSLKVRARWKIEDLARGQWQ VITELPP S Q+VLEEIEE TNPK+KLGKKSLT Sbjct: 243 YETGRGSLKVRARWKIEDLARGQWQLVITELPPNTSGQKVLEEIEEQTNPKIKLGKKSLT 302 Query: 303 PEQQAQKAAILGLLDAVRDESGRDAPVRLVFEPKSKNQDQTEFMNTLLAQTSLETSASLN 362 PEQ K +LGLLDAVRDESG+DAPVRLVFEPKS DQTEF+NTLLA TSLE++A+LN Sbjct: 303 PEQLQTKQTLLGLLDAVRDESGKDAPVRLVFEPKSSRIDQTEFVNTLLAHTSLESNATLN 362 Query: 363 LVMIGGDGRPRQKNLTDILSEWISFRFETVTRRTQFRMQKVNDRIHILEGREAVLLNIDK 422 LVM+G DGRPRQK + ++L EWI FRF TVTRR+Q R+ KVN+RIHILEGR V LNID+ Sbjct: 363 LVMVGADGRPRQKGIGEMLHEWIGFRFTTVTRRSQHRLNKVNERIHILEGRMIVFLNIDE 422 Query: 423 VIRIIRESDEPKPALIEAFRLSDRQAEDILEIRLRQLARLEAIKIQQELAELRNEKSTLQ 482 VIRIIRES+EPK ALIEAF+LSDRQAEDILEIRLRQLARLEAIKI++EL+ELR+EK+ L+ Sbjct: 423 VIRIIRESEEPKAALIEAFKLSDRQAEDILEIRLRQLARLEAIKIEKELSELRDEKAKLE 482 Query: 483 DLLDNPSSMKKLVIKEIEGDAKTYGDARRTIIEEAERATFEQKVIDEPVTVIISQKGWVR 542 +LL + +MK+L+IKEIE DAK YGD RRT+I++ +RATFE +V+DEPVTV++SQKGWVR Sbjct: 483 ELLGSEPAMKRLLIKEIEADAKQYGDDRRTLIQQEKRATFEARVVDEPVTVVVSQKGWVR 542 Query: 543 ARTGHGHDATQFTFKAGDSLYGAFECRTVDNLLAFGSNGRVYTIAVNALPNARGDGVPVT 602 A GHG D FTFKAGD LY AF+CRT D L+A+GS GRVY++AV+ LP RGDGVPVT Sbjct: 543 ALKGHGLDPAGFTFKAGDGLYAAFQCRTPDMLIAWGSKGRVYSVAVSQLPGGRGDGVPVT 602 Query: 603 TLLELASGSSILHYFAGPADTTLLLASDAAAGFIAKASDMFGRVKGGKSFFTLDEGALPL 662 +L+EL SG+ ++HY+A A+ LLLAS GFIAK DM RVK GK+F T+DEGA PL Sbjct: 603 SLIELESGTHLMHYYAASAEQALLLASSNGFGFIAKVGDMVSRVKAGKAFMTIDEGATPL 662 Query: 663 APTPVPTDASAVACVSGNGRLLVFGLDEMKTLSSGGRGVNLMELEKNEKLVAAQAISQKG 722 AP P+ DA+ VAC+SG GRLLVFGLDEMKTLS GGRGV LM L+ NE L A AIS G Sbjct: 663 APMPMLPDATQVACLSGGGRLLVFGLDEMKTLSGGGRGVILMALDPNEVLKQALAISNAG 722 Query: 723 VVVYGTGNVGKAKEIALSAVSLALHIGKRARKGKALESRIK-VTGLR 768 VV+ G K E LS +L ++GKRARKG+ ++++K VT LR Sbjct: 723 VVLQGVYR-NKPMEEELSGKALEPNVGKRARKGRVPDTKLKEVTSLR 768